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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs196586
log Bayes Factor = 13.7618
Chromosome 7   position 36,320,821  (GRCh37) Explore rs196586 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
K55-K64 Other diseases of intestines
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
0.998 0.002 0.000
I20 Angina pectoris
0.998 0.002 0.000
K63 Other diseases of intestine
0.997 0.003 0.000
I20.9 Angina pectoris, unspecified
0.997 0.003 0.000
M20-M25 Other joint disorders
0.997 0.003 0.000
K63.5 Polyp of colon
0.994 0.006 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.991 0.009 0.000
I10-I15 Hypertensive diseases
0.985 0.015 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.985 0.015 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.982 0.018 0.000
M25 Other joint disorders, not elsewhere classified
0.979 0.021 0.000
Chapter VI Diseases of the nervous system
0.977 0.023 0.000
I10 Essential (primary) hypertension
0.974 0.026 0.000
I25.2 Old myocardial infarction
0.973 0.027 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.971 0.029 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.970 0.030 0.000
M50-M54 Other dorsopathies
0.970 0.030 0.000
K90-K93 Other diseases of the digestive system
0.967 0.033 0.000
E10-E14 Diabetes mellitus
0.962 0.038 0.000
Chapter XXI Factors influencing health status and contact with health services
0.954 0.046 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.951 0.049 0.000
Z60 Problems related to social environment
0.946 0.054 0.000
E11 Non-insulin-dependent diabetes mellitus
0.945 0.055 0.000
K70-K77 Diseases of liver
0.944 0.056 0.000
Z60.2 Living alone
0.942 0.058 0.000
K61 Abscess of anal and rectal regions
0.941 0.059 0.000
K56.6 Other and unspecified intestinal obstruction
0.939 0.061 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.936 0.064 0.000
M25.5 Pain in joint
0.935 0.065 0.000
E11.9 Without complications
0.934 0.066 0.000
M54 Dorsalgia
0.930 0.070 0.000
Chapter V Mental and behavioural disorders
0.929 0.071 0.000
M20 Acquired deformities of fingers and toes
0.928 0.072 0.000
G90-G99 Other disorders of the nervous system
0.925 0.075 0.000
I25.1 Atherosclerotic heart disease
0.923 0.077 0.000
I77 Other disorders of arteries and arterioles
0.912 0.088 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.912 0.088 0.000
Z13 Special screening examination for other diseases and disorders
0.904 0.096 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.903 0.097 0.000
O60-O75 Complications of labour and delivery
0.902 0.098 0.000
K61.0 Anal abscess
0.901 0.099 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.901 0.099 0.000
S00-S09 Injuries to the head
0.898 0.102 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.894 0.106 0.000
K50-K52 Noninfective enteritis and colitis
0.892 0.108 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.890 0.110 0.000
K60 Fissure and fistula of anal and rectal regions
0.889 0.111 0.000
G30-G32 Other degenerative diseases of the nervous system
0.882 0.118 0.000
I74 Arterial embolism and thrombosis
0.882 0.118 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.881 0.119 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.878 0.122 0.000
K55 Vascular disorders of intestine
0.874 0.126 0.000
K92 Other diseases of digestive system
0.873 0.127 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.872 0.128 0.000
I22 Subsequent myocardial infarction
0.869 0.131 0.000
I73 Other peripheral vascular diseases
0.869 0.131 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.863 0.137 0.000
K65-K67 Diseases of peritoneum
0.861 0.139 0.000
M25.4 Effusion of joint
0.861 0.139 0.000
M20.4 Other hammer toe(s) (acquired)
0.858 0.142 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.853 0.147 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.851 0.149 0.000
K74 Fibrosis and cirrhosis of liver
0.850 0.150 0.000
K63.9 Disease of intestine, unspecified
0.850 0.150 0.000
K92.2 Gastro-intestinal haemorrhage, unspecified
0.849 0.151 0.000
K04 Diseases of pulp and periapical tissues
0.849 0.151 0.000
S01 Open wound of head
0.845 0.155 0.000
K56.7 Ileus, unspecified
0.843 0.157 0.000
M54.3 Sciatica
0.840 0.160 0.000
Z13.6 Special screening examination for cardiovascular disorders
0.840 0.160 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.838 0.162 0.000
M40-M43 Deforming dorsopathies
0.838 0.162 0.000
Chapter VIII Diseases of the ear and mastoid process
0.837 0.163 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.836 0.164 0.000
K63.1 Perforation of intestine (nontraumatic)
0.834 0.166 0.000
I77.1 Stricture of artery
0.832 0.168 0.000
I20.0 Unstable angina
0.828 0.172 0.000
K59 Other functional intestinal disorders
0.828 0.172 0.000
K35-K38 Diseases of appendix
0.826 0.174 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.826 0.174 0.000
I72 Other aneurysm
0.823 0.177 0.000
O72 Postpartum haemorrhage
0.822 0.178 0.000
E20-E35 Disorders of other endocrine glands
0.821 0.179 0.000
K63.4 Enteroptosis
0.818 0.181 0.000
G95 Other diseases of spinal cord
0.818 0.182 0.000
K04.5 Chronic apical periodontitis
0.818 0.182 0.000
K76 Other diseases of liver
0.817 0.183 0.000
M24 Other specific joint derangements
0.817 0.183 0.000
M20.3 Other deformity of hallux (acquired)
0.813 0.187 0.000
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.812 0.188 0.000
M54.1 Radiculopathy
0.811 0.189 0.000
O14.9 Preeclampsia, unspecified
0.811 0.189 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.811 0.189 0.000
K51 Ulcerative colitis
0.809 0.191 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.809 0.191 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.805 0.195 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.803 0.197 0.000
K60.3 Anal fistula
0.802 0.198 0.000
S01.8 Open wound of other parts of head
0.800 0.200 0.000
Z13.1 Special screening examination for diabetes mellitus
0.797 0.203 0.000
E50-E64 Other nutritional deficiencies
0.796 0.204 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.796 0.204 0.000
F60-F69 Disorders of adult personality and behaviour
0.793 0.207 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.793 0.207 0.000
M22 Disorders of patella
0.791 0.209 0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.790 0.210 0.000
I73.9 Peripheral vascular disease, unspecified
0.789 0.211 0.000
M05-M14 Inflammatory polyarthropathies
0.789 0.211 0.000
I71 Aortic aneurysm and dissection
0.786 0.214 0.000
M25.46 Effusion of joint (Lower leg)
0.783 0.217 0.000
M20.2 Hallux rigidus
0.783 0.217 0.000
K65 Peritonitis
0.782 0.218 0.000
Z63 Other problems related to primary support group, including family circumstances
0.780 0.220 0.000
G54 Nerve root and plexus disorders
0.779 0.221 0.000
M25.50 Pain in joint (Multiple sites)
0.779 0.221 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.779 0.221 0.000
Z57 Occupational exposure to risk-factors
0.779 0.221 0.000
F99-F99 Unspecified mental disorder
0.777 0.223 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.777 0.223 0.000
M80-M85 Disorders of bone density and structure
0.777 0.223 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.775 0.225 0.000
K90 Intestinal malabsorption
0.774 0.226 0.000
K74.6 Other and unspecified cirrhosis of liver
0.774 0.226 0.000
K11 Diseases of salivary glands
0.770 0.230 0.000
M53 Other dorsopathies, not elsewhere classified
0.769 0.231 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.769 0.231 0.000
K51.9 Ulcerative colitis, unspecified
0.767 0.233 0.000
O36 Maternal care for other known or suspected foetal problems
0.765 0.235 0.000
S60-S69 Injuries to the wrist and hand
0.765 0.235 0.000
M54.5 Low back pain
0.764 0.236 0.000
M25.59 Pain in joint (Site unspecified)
0.763 0.237 0.000
K55.9 Vascular disorder of intestine, unspecified
0.763 0.237 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.762 0.238 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.761 0.239 0.000
I70 Atherosclerosis
0.757 0.243 0.000
E00-E07 Disorders of thyroid gland
0.755 0.245 0.000
M51 Other intervertebral disk disorders
0.752 0.248 0.000
G95.2 Cord compression, unspecified
0.748 0.252 0.000
M21 Other acquired deformities of limbs
0.747 0.253 0.000
M65-M68 Disorders of synovium and tendon
0.747 0.253 0.000
E11.5 With peripheral circulatory complications
0.744 0.256 0.000
E13 Other specified diabetes mellitus
0.744 0.256 0.000
Z13.5 Special screening examination for eye and ear disorders
0.741 0.259 0.000
O72.1 Other immediate postpartum haemorrhage
0.741 0.259 0.000
K63.2 Fistula of intestine
0.741 0.259 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.740 0.260 0.000
M45-M49 Spondylopathies
0.739 0.261 0.000
M54.39 Sciatica (Site unspecified)
0.739 0.261 0.000
M23 Internal derangement of knee
0.738 0.262 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.738 0.262 0.000
S06 Intracranial injury
0.735 0.265 0.000
M70-M79 Other soft tissue disorders
0.732 0.268 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.731 0.269 0.000
O61 Failed induction of labour
0.730 0.270 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.730 0.270 0.000
T40.2 Other opioids
0.730 0.270 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.728 0.272 0.000
T51 Toxic effect of alcohol
0.726 0.274 0.000
K56.5 Intestinal adhesions [bands] with obstruction
0.726 0.274 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.725 0.275 0.000
O42 Premature rupture of membranes
0.725 0.275 0.000
M25.57 Pain in joint (Ankle and foot)
0.724 0.276 0.000
I20.1 Angina pectoris with documented spasm
0.723 0.277 0.000
I25.5 Ischaemic cardiomyopathy
0.722 0.277 0.000
G30 Alzheimer's disease
0.722 0.278 0.000
E11.1 With ketoacidosis
0.720 0.280 0.000
I60-I69 Cerebrovascular diseases
0.720 0.280 0.000
K72 Hepatic failure, not elsewhere classified
0.719 0.281 0.000
H65-H75 Diseases of middle ear and mastoid
0.719 0.281 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.719 0.281 0.000
M50 Cervical disk disorders
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
S40-S49 Injuries to the shoulder and upper arm
0.717 0.283 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.717 0.283 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
M43 Other deforming dorsopathies
0.716 0.284 0.000
I25.6 Silent myocardial ischaemia
0.716 0.284 0.000
I25.4 Coronary artery aneurysm
0.716 0.284 0.000
I25.3 Aneurysm of heart
0.716 0.284 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.716 0.284 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.715 0.285 0.000
K75 Other inflammatory liver diseases
0.715 0.285 0.000
K63.0 Abscess of intestine
0.715 0.285 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.714 0.285 0.000
M34 Systemic sclerosis
0.714 0.285 0.000
M33 Dermatopolymyositis
0.714 0.285 0.000
M32 Systemic lupus erythematosus
0.714 0.285 0.000
M30 Polyarteritis nodosa and related conditions
0.714 0.285 0.000
Chapter XXII Codes for special purposes
0.714 0.285 0.000
O30 Multiple gestation
0.714 0.286 0.000
G58 Other mononeuropathies
0.714 0.286 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.713 0.287 0.000
E27 Other disorders of adrenal gland
0.713 0.287 0.000
I11 Hypertensive heart disease
0.712 0.288 0.000
E14 Unspecified diabetes mellitus
0.712 0.288 0.000
K65.9 Peritonitis, unspecified
0.712 0.288 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.711 0.289 0.000
I77.6 Arteritis, unspecified
0.710 0.290 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.710 0.290 0.000
T79-T79 Certain early complications of trauma
0.710 0.290 0.000
Z03.8 Observation for other suspected diseases and conditions
0.709 0.291 0.000
S50-S59 Injuries to the elbow and forearm
0.709 0.291 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.709 0.291 0.000
I15 Secondary hypertension
0.706 0.294 0.000
I13 Hypertensive heart and renal disease
0.706 0.294 0.000
E40-E46 Malnutrition
0.706 0.294 0.000
Chapter I Certain infectious and parasitic diseases
0.705 0.295 0.000
K09 Cysts of oral region, not elsewhere classified
0.704 0.296 0.000
O85-O92 Complications predominantly related to the puerperium
0.704 0.296 0.000
T66-T78 Other and unspecified effects of external causes
0.704 0.296 0.000
K59.1 Functional diarrhoea
0.704 0.296 0.000
S02 Fracture of skull and facial bones
0.703 0.297 0.000
O73 Retained placenta and membranes, without haemorrhage
0.702 0.298 0.000
M25.9 Joint disorder, unspecified
0.702 0.298 0.000
M25.8 Other specified joint disorders
0.702 0.298 0.000
M25.3 Other instability of joint
0.702 0.298 0.000
M25.2 Flail joint
0.702 0.298 0.000
M25.1 Fistula of joint
0.702 0.298 0.000
M25.0 Haemarthrosis
0.702 0.298 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.701 0.299 0.000
G70-G73 Diseases of myoneural junction and muscle
0.700 0.300 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.700 0.300 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.698 0.302 0.000
M31 Other necrotising vasculopathies
0.698 0.302 0.000
M54.6 Pain in thoracic spine
0.698 0.302 0.000
S80-S89 Injuries to the knee and lower leg
0.698 0.302 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.697 0.303 0.000
T33-T35 Frostbite
0.696 0.303 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.696 0.303 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.696 0.303 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.696 0.303 0.000
T00-T07 Injuries involving multiple body regions
0.696 0.303 0.000
S10-S19 Injuries to the neck
0.696 0.303 0.000
K56.3 Gallstone ileus
0.696 0.304 0.000
K56.1 Intussusception
0.696 0.304 0.000
K56.0 Paralytic ileus
0.696 0.304 0.000
F60 Specific personality disorders
0.696 0.304 0.000
I77.8 Other specified disorders of arteries and arterioles
0.694 0.306 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.694 0.306 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.694 0.306 0.000
E65-E68 Obesity and other hyperalimentation
0.693 0.307 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.692 0.308 0.000
K91.4 Colostomy and enterostomy malfunction
0.692 0.308 0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)
0.692 0.308 0.000
K76.9 Liver disease, unspecified
0.692 0.308 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.691 0.309 0.000
K55.2 Angiodysplasia of colon
0.690 0.310 0.000
E12 Malnutrition-related diabetes mellitus
0.690 0.310 0.000
K59.4 Anal spasm
0.689 0.310 0.000
I12 Hypertensive renal disease
0.689 0.311 0.000
M54.36 Sciatica (Lumbar region)
0.688 0.312 0.000
M24.1 Other articular cartilage disorders
0.688 0.312 0.000
G91 Hydrocephalus
0.688 0.312 0.000
O66 Other obstructed labour
0.686 0.313 0.000
S70-S79 Injuries to the hip and thigh
0.686 0.314 0.000
K04.9 Other and unspecified diseases of pulp and periapical tissues
0.685 0.315 0.000
Z65 Problems related to other psychosocial circumstances
0.682 0.318 0.000
Z64 Problems related to certain psychosocial circumstances
0.682 0.318 0.000
Z62 Other problems related to upbringing
0.682 0.318 0.000
Z61 Problems related to negative life events in childhood
0.682 0.318 0.000
Z59 Problems related to housing and economic circumstances
0.682 0.318 0.000
Z58 Problems related to physical environment
0.682 0.318 0.000
Z56 Problems related to employment and unemployment
0.682 0.318 0.000
Z55 Problems related to education and literacy
0.682 0.318 0.000
M54.2 Cervicalgia
0.681 0.319 0.000
K37 Unspecified appendicitis
0.681 0.319 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.680 0.320 0.000
Z60.9 Problem related to social environment, unspecified
0.678 0.322 0.000
Z60.8 Other problems related to social environment
0.678 0.322 0.000
Z60.5 Target of perceived adverse discrimination and persecution
0.678 0.322 0.000
Z60.4 Social exclusion and rejection
0.678 0.322 0.000
Z60.3 Acculturation difficulty
0.678 0.322 0.000
Z60.1 Atypical parenting situation
0.678 0.322 0.000
Z60.0 Problems of adjustment to life-cycle transitions
0.678 0.322 0.000
E11.8 With unspecified complications
0.678 0.322 0.000
E11.7 With multiple complications
0.678 0.322 0.000
E11.6 With other specified complications
0.678 0.322 0.000
E11.2 With renal complications
0.678 0.322 0.000
E11.0 With coma
0.678 0.322 0.000
M54.4 Lumbago with sciatica
0.677 0.322 0.000
M13 Other arthritis
0.677 0.323 0.000
K77 Liver disorders in diseases classified elsewhere
0.677 0.323 0.000
K73 Chronic hepatitis, not elsewhere classified
0.677 0.323 0.000
K71 Toxic liver disease
0.677 0.323 0.000
K56.2 Volvulus
0.677 0.323 0.000
K63.3 Ulcer of intestine
0.676 0.324 0.000
S01.0 Open wound of scalp
0.676 0.324 0.000
I72.4 Aneurysm of artery of lower extremity
0.675 0.325 0.000
K61.4 Intrasphincteric abscess
0.675 0.325 0.000
K61.2 Anorectal abscess
0.675 0.325 0.000
K61.1 Rectal abscess
0.675 0.325 0.000
H80-H83 Diseases of inner ear
0.675 0.325 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.674 0.326 0.000
Z13.9 Special screening examination, unspecified
0.674 0.326 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.673 0.327 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.673 0.327 0.000
G93 Other disorders of brain
0.672 0.327 0.000
O15 Eclampsia
0.671 0.329 0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.671 0.329 0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria
0.671 0.329 0.000
M25.58 Pain in joint (Other)
0.670 0.330 0.000
M25.52 Pain in joint (Upper arm)
0.670 0.330 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.670 0.330 0.000
Z03.2 Observation for suspected mental and behavioural disorders
0.670 0.330 0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)
0.669 0.331 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.668 0.332 0.000
M54.16 Radiculopathy (Lumbar region)
0.668 0.332 0.000
F99 Mental disorder, not otherwise specified
0.668 0.332 0.000
K50 Crohn's disease [regional enteritis]
0.668 0.332 0.000
M54.8 Other dorsalgia
0.667 0.333 0.000
M54.0 Panniculitis affecting regions of neck and back
0.667 0.333 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.666 0.334 0.000
F80-F89 Disorders of psychological development
0.666 0.334 0.000
F70-F79 Mental retardation
0.666 0.334 0.000
K61.3 Ischiorectal abscess
0.665 0.335 0.000
K76.8 Other specified diseases of liver
0.665 0.335 0.000
O48 Prolonged pregnancy
0.664 0.335 0.000
T59 Toxic effect of other gases, fumes and vapours
0.664 0.336 0.000
K74.0 Hepatic fibrosis
0.664 0.336 0.000
O43 Placental disorders
0.664 0.336 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.663 0.336 0.000
G90 Disorders of autonomic nervous system
0.663 0.336 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.663 0.336 0.000
G92 Toxic encephalopathy
0.663 0.336 0.000
M20.0 Deformity of finger(s)
0.663 0.337 0.000
G54.4 Lumbosacral root disorders, not elsewhere classified
0.663 0.337 0.000
K04.6 Periapical abscess with sinus
0.662 0.338 0.000
S01.4 Open wound of cheek and temporomandibular area
0.662 0.338 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.661 0.339 0.000
K12 Stomatitis and related lesions
0.660 0.340 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.657 0.341 0.002
M54.57 Low back pain (Lumbosacral region)
0.659 0.341 0.000
E11.3 With ophthalmic complications
0.657 0.343 0.000
S20-S29 Injuries to the thorax
0.656 0.343 0.000
O63 Long labour
0.656 0.344 0.000
M54.17 Radiculopathy (Lumbosacral region)
0.656 0.344 0.000
S90-S99 Injuries to the ankle and foot
0.656 0.344 0.000
K60.2 Anal fissure, unspecified
0.655 0.345 0.000
I77.5 Necrosis of artery
0.654 0.346 0.000
I77.4 Coeliac artery compression syndrome
0.654 0.346 0.000
I77.3 Arterial fibromuscular dysplasia
0.654 0.346 0.000
I77.2 Rupture of artery
0.654 0.346 0.000
I77.0 Arteriovenous fistula, acquired
0.654 0.346 0.000
Z10 Routine general health check-up of defined subpopulation
0.654 0.346 0.000
I69 Sequelae of cerebrovascular disease
0.649 0.351 0.000
Z13.8 Special screening examination for other specified diseases and disorders
0.648 0.352 0.000
Z13.7 Special screening examination for congenital malformations, deformations and chromosomal abnormalities
0.648 0.352 0.000
Z13.4 Special screening examination for certain developmental disorders in childhood
0.648 0.352 0.000
Z13.3 Special screening examination for mental and behavioural disorders
0.648 0.352 0.000
Z13.2 Special screening examination for nutritional disorders
0.648 0.352 0.000
G96 Other disorders of central nervous system
0.648 0.352 0.000
M86-M90 Other osteopathies
0.647 0.353 0.000
O74 Complications of anaesthesia during labour and delivery
0.647 0.353 0.000
O71 Other obstetric trauma
0.647 0.353 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.647 0.353 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.647 0.353 0.000
O62 Abnormalities of forces of labour
0.647 0.353 0.000
O60 Preterm delivery
0.647 0.353 0.000
O41 Other disorders of amniotic fluid and membranes
0.647 0.353 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.646 0.354 0.000
G52 Disorders of other cranial nerves
0.646 0.354 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.645 0.355 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.644 0.356 0.000
S08 Traumatic amputation of part of head
0.644 0.356 0.000
S07 Crushing injury of head
0.644 0.356 0.000
S05 Injury of eye and orbit
0.644 0.356 0.000
S04 Injury of cranial nerves
0.644 0.356 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.644 0.356 0.000
M25.54 Pain in joint (Hand)
0.643 0.356 0.000
K11.2 Sialoadenitis
0.643 0.357 0.000
Q60-Q64 Congenital malformations of the urinary system
0.643 0.357 0.000
O45 Premature separation of placenta [abruptio placentae]
0.641 0.359 0.000
O44 Placenta praevia
0.641 0.359 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.641 0.359 0.000
O33 Maternal care for known or suspected disproportion
0.641 0.359 0.000
O31 Complications specific to multiple gestation
0.641 0.359 0.000
O40 Polyhydramnios
0.641 0.359 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.640 0.360 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.639 0.361 0.000
K60.1 Chronic anal fissure
0.639 0.361 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.639 0.361 0.000
O72.0 Third-stage haemorrhage
0.638 0.362 0.000
Z03.4 Observation for suspected myocardial infarction
0.638 0.362 0.000
K60.5 Anorectal fistula
0.637 0.363 0.000
K60.4 Rectal fistula
0.637 0.363 0.000
K60.0 Acute anal fissure
0.637 0.363 0.000
T51.0 Ethanol
0.637 0.363 0.000
O12.1 Gestational proteinuria
0.637 0.363 0.000
E27.1 Primary adrenocortical insufficiency
0.636 0.364 0.000
T63 Toxic effect of contact with venomous animals
0.636 0.364 0.000
Z63.0 Problems in relationship with spouse or partner
0.635 0.365 0.000
S09 Other and unspecified injuries of head
0.635 0.365 0.000
Q50-Q56 Congenital malformations of genital organs
0.634 0.366 0.000
G83 Other paralytic syndromes
0.634 0.366 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.633 0.367 0.000
I72.3 Aneurysm of iliac artery
0.633 0.367 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.633 0.367 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.632 0.367 0.000
I74.8 Embolism and thrombosis of other arteries
0.632 0.367 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.632 0.367 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.632 0.367 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.632 0.367 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.632 0.367 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.632 0.368 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.632 0.368 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.632 0.368 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.632 0.368 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.632 0.368 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.632 0.368 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.632 0.368 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.632 0.368 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.632 0.368 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.632 0.368 0.000
T36 Poisoning by systemic antibiotics
0.632 0.368 0.000
G20-G26 Extrapyramidal and movement disorders
0.631 0.369 0.000
K07 Dentofacial anomalies [including malocclusion]
0.630 0.370 0.000
K10 Other diseases of jaws
0.630 0.370 0.000
K03 Other diseases of hard tissues of teeth
0.630 0.370 0.000
K00 Disorders of tooth development and eruption
0.630 0.370 0.000
M43.1 Spondylolisthesis
0.629 0.371 0.000
I78 Diseases of capillaries
0.628 0.371 0.000
M23.3 Other meniscus derangements
0.629 0.371 0.000
Z57.2 Occupational exposure to dust
0.628 0.372 0.000
E61 Deficiency of other nutrient elements
0.627 0.373 0.000
K52 Other non-infective gastro-enteritis and colitis
0.627 0.373 0.000
K35 Acute appendicitis
0.627 0.373 0.000
K55.8 Other vascular disorders of intestine
0.626 0.373 0.000
K55.1 Chronic vascular disorders of intestine
0.626 0.373 0.000
K92.8 Other specified diseases of digestive system
0.626 0.374 0.000
G82 Paraplegia and tetraplegia
0.625 0.375 0.000
K91.9 Postprocedural disorder of digestive system, unspecified
0.625 0.375 0.000
K91.5 Postcholecystectomy syndrome
0.625 0.375 0.000
K91.2 Postsurgical malabsorption, not elsewhere classified
0.625 0.375 0.000
K91.1 Postgastric surgery syndromes
0.625 0.375 0.000
K91.0 Vomiting following gastro-intestinal surgery
0.625 0.375 0.000
O36.5 Maternal care for poor foetal growth
0.625 0.375 0.000
M53.3 Sacrococcygeal disorders, not elsewhere classified
0.624 0.376 0.000
H65 Nonsuppurative otitis media
0.624 0.376 0.000
I22.8 Subsequent myocardial infarction of other sites
0.623 0.377 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.623 0.377 0.000
M85 Other disorders of bone density and structure
0.623 0.377 0.000
I73.8 Other specified peripheral vascular diseases
0.623 0.377 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.623 0.377 0.000
G50 Disorders of trigeminal nerve
0.623 0.377 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.622 0.378 0.000
M22.4 Chondromalacia patellae
0.622 0.378 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.620 0.379 0.000
M25.7 Osteophyte
0.620 0.380 0.000
Z00.5 Examination of potential donor of organ and tissue
0.620 0.380 0.000
G55.3 Nerve root and plexus compressions in other dorsopathies
0.619 0.381 0.000
Z00.0 General medical examination
0.619 0.381 0.000
O14.2 HELLP syndrome
0.619 0.381 0.000
O14.1 Severe preeclampsia
0.619 0.381 0.000
O14.0 Moderate preeclampsia
0.619 0.381 0.000
M25.51 Pain in joint (Shoulder region)
0.618 0.382 0.000
M20.1 Hallux valgus (acquired)
0.618 0.382 0.000
K67 Disorders of peritoneum in infectious diseases classified elsewhere
0.617 0.383 0.000
M25.49 Effusion of joint (Site unspecified)
0.617 0.383 0.000
M25.48 Effusion of joint (Other)
0.617 0.383 0.000
M25.45 Effusion of joint (Pelvic region and thigh)
0.617 0.383 0.000
M25.44 Effusion of joint (Hand)
0.617 0.383 0.000
M25.43 Effusion of joint (Forearm)
0.617 0.383 0.000
M25.42 Effusion of joint (Upper arm)
0.617 0.383 0.000
M25.41 Effusion of joint (Shoulder region)
0.617 0.383 0.000
M25.40 Effusion of joint (Multiple sites)
0.617 0.383 0.000
S62 Fracture at wrist and hand level
0.617 0.383 0.000
I74.5 Embolism and thrombosis of iliac artery
0.616 0.383 0.000
M35 Other systemic involvement of connective tissue
0.616 0.384 0.000
I86 Varicose veins of other sites
0.616 0.384 0.000
I24 Other acute ischaemic heart diseases
0.615 0.385 0.000
O70 Perineal laceration during delivery
0.615 0.385 0.000
G54.9 Nerve root and plexus disorder, unspecified
0.615 0.385 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.613 0.387 0.000
S64 Injury of nerves at wrist and hand level
0.612 0.387 0.000
M41 Scoliosis
0.612 0.388 0.000
E10 Insulin-dependent diabetes mellitus
0.611 0.389 0.000
T39.1 4-Aminophenol derivatives
0.610 0.390 0.000
T65 Toxic effect of other and unspecified substances
0.610 0.390 0.000
T62 Toxic effect of other noxious substances eaten as food
0.610 0.390 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.610 0.390 0.000
T60 Toxic effect of pesticides
0.610 0.390 0.000
T57 Toxic effect of other inorganic substances
0.610 0.390 0.000
T56 Toxic effect of metals
0.610 0.390 0.000
T54 Toxic effect of corrosive substances
0.610 0.390 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.610 0.390 0.000
T52 Toxic effect of organic solvents
0.610 0.390 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.610 0.390 0.000
T58 Toxic effect of carbon monoxide
0.610 0.390 0.000
T55 Toxic effect of soaps and detergents
0.610 0.390 0.000
O72.2 Delayed and secondary postpartum haemorrhage
0.610 0.390 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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