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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1988564
log Bayes Factor = 48.348
Chromosome 6   position 32,753,682  (GRCh37) Explore rs1988564 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
M07.3 Other psoriatic arthropathies
0.000 0.000 1.000
M07 Psoriatic and enteropathic arthropathies
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
C44 Other malignant neoplasms of skin
0.000 0.000 1.000
L40 Psoriasis
0.000 0.001 0.999
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.001 0.999
C44.7 Skin of lower limb, including hip
0.000 0.001 0.999
M05 Seropositive rheumatoid arthritis
0.000 0.001 0.999
L57.0 Actinic keratosis
0.000 0.001 0.999
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.001 0.999
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.003 0.997
L40.9 Psoriasis, unspecified
0.000 0.003 0.997
C44.6 Skin of upper limb, including shoulder
0.000 0.003 0.997
E20-E35 Disorders of other endocrine glands
0.000 0.004 0.996
E10.3 With ophthalmic complications
0.000 0.004 0.996
E05.9 Thyrotoxicosis, unspecified
0.000 0.006 0.994
C44.3 Skin of other and unspecified parts of face
0.000 0.006 0.994
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.008 0.992
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.009 0.991
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.010 0.990
E23 Hypofunction and other disorders of pituitary gland
0.000 0.011 0.989
G35-G37 Demyelinating diseases of the central nervous system
0.988 0.012 0.000
E83.1 Disorders of iron metabolism
0.986 0.014 0.000
E10.9 Without complications
0.000 0.015 0.985
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.015 0.985
G37 Other demyelinating diseases of central nervous system
0.983 0.017 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.020 0.980
G37.9 Demyelinating disease of central nervous system, unspecified
0.976 0.024 0.000
E70-E90 Metabolic disorders
0.000 0.036 0.964
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.037 0.963
E11 Non-insulin-dependent diabetes mellitus
0.000 0.047 0.953
L40-L45 Papulosquamous disorders
0.000 0.053 0.947
E78.0 Pure hypercholesterolaemia
0.000 0.058 0.942
E23.6 Other disorders of pituitary gland
0.000 0.069 0.931
E27 Other disorders of adrenal gland
0.000 0.070 0.930
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.072 0.928
E23.7 Disorder of pituitary gland, unspecified
0.000 0.074 0.926
E11.3 With ophthalmic complications
0.000 0.082 0.918
C44.4 Skin of scalp and neck
0.000 0.082 0.918
C44.2 Skin of ear and external auricular canal
0.000 0.087 0.913
C43-C44 Melanoma and other malignant neoplasms of skin
0.000 0.092 0.908
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.113 0.887
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.117 0.883
E10.5 With peripheral circulatory complications
0.000 0.118 0.882
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.118 0.882
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.120 0.880
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.121 0.879
G37.8 Other specified demyelinating diseases of central nervous system
0.877 0.123 0.000
E06 Thyroiditis
0.000 0.127 0.873
E27.1 Primary adrenocortical insufficiency
0.000 0.134 0.866
E10.1 With ketoacidosis
0.000 0.137 0.863
E78.5 Hyperlipidaemia, unspecified
0.000 0.149 0.851
C44.0 Skin of lip
0.000 0.152 0.848
D00-D09 In situ neoplasms
0.000 0.157 0.843
E23.2 Diabetes insipidus
0.000 0.157 0.843
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.000 0.158 0.842
Chapter II Neoplasms
0.000 0.158 0.842
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.159 0.841
L43 Lichen planus
0.000 0.160 0.840
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.161 0.839
E10.0 With coma
0.000 0.161 0.839
E11.9 Without complications
0.000 0.162 0.838
E78.2 Mixed hyperlipidaemia
0.000 0.167 0.833
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.168 0.832
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.000 0.168 0.832
D04 Carcinoma in situ of skin
0.000 0.169 0.831
D06 Carcinoma in situ of cervix uteri
0.000 0.171 0.829
L40.1 Generalised pustular psoriasis
0.000 0.175 0.825
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.000 0.181 0.819
C83 Diffuse non-Hodgkin's lymphoma
0.000 0.181 0.819
D06.9 Cervix, unspecified
0.000 0.182 0.818
M10 Gout
0.000 0.182 0.818
E06.3 Autoimmune thyroiditis
0.000 0.182 0.818
E78.6 Lipoprotein deficiency
0.000 0.186 0.814
E04 Other non-toxic goitre
0.000 0.187 0.813
E89.0 Postprocedural hypothyroidism
0.000 0.189 0.811
C83.3 Large cell (diffuse)
0.000 0.191 0.809
E28 Ovarian dysfunction
0.000 0.193 0.807
M06.0 Seronegative rheumatoid arthritis
0.000 0.195 0.805
L40.0 Psoriasis vulgaris
0.000 0.196 0.804
M06.3 Rheumatoid nodule
0.000 0.196 0.804
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.197 0.803
G36 Other acute disseminated demyelination
0.800 0.200 0.000
E78.1 Pure hyperglyceridaemia
0.000 0.207 0.793
E10.2 With renal complications
0.000 0.212 0.788
E23.0 Hypopituitarism
0.000 0.213 0.787
E29 Testicular dysfunction
0.000 0.213 0.787
E11.2 With renal complications
0.000 0.215 0.785
E88 Other metabolic disorders
0.000 0.223 0.777
D37-D48 Neoplasms of uncertain or unknown behaviour
0.000 0.224 0.776
E13 Other specified diabetes mellitus
0.000 0.225 0.775
E24 Cushing's syndrome
0.000 0.226 0.774
M06.4 Inflammatory polyarthropathy
0.000 0.230 0.770
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.231 0.769
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.000 0.235 0.765
D04.5 Skin of trunk
0.000 0.237 0.763
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.249 0.751
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.251 0.749
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.000 0.255 0.745
E26 Hyperaldosteronism
0.000 0.259 0.741
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.000 0.260 0.740
D04.3 Skin of other and unspecified parts of face
0.000 0.261 0.739
C85.1 B-cell lymphoma, unspecified
0.000 0.263 0.737
E10.8 With unspecified complications
0.000 0.264 0.736
E11.1 With ketoacidosis
0.000 0.265 0.735
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.266 0.734
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.267 0.733
L40.4 Guttate psoriasis
0.000 0.270 0.730
E04.0 Non-toxic diffuse goitre
0.000 0.271 0.729
E84 Cystic fibrosis
0.000 0.271 0.729
C73 Malignant neoplasm of thyroid gland
0.000 0.272 0.728
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.272 0.728
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
M07.38 Other psoriatic arthropathies (Other)
0.000 0.283 0.717
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.283 0.717
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.283 0.717
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
M07.6 Other enteropathic arthropathies
0.000 0.283 0.717
M07.5 Arthropathy in ulcerative colitis
0.000 0.283 0.717
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.283 0.717
M07.2 Psoriatic spondylitis
0.000 0.283 0.717
M07.1 Arthritis mutilans
0.000 0.283 0.717
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.283 0.717
C44.8 Overlapping lesion of skin
0.000 0.283 0.717
L40.3 Pustulosis palmaris et plantaris
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.716
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.716
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.716
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.716
M05.8 Other seropositive rheumatoid arthritis
0.000 0.283 0.716
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.283 0.716
M05.1 Rheumatoid lung disease
0.000 0.283 0.716
M05.0 Felty's syndrome
0.000 0.283 0.716
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.284 0.716
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.284 0.716
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.284 0.716
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.284 0.716
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.284 0.716
D43.0 Brain, supratentorial
0.000 0.284 0.716
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.285 0.715
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.286 0.714
E32 Diseases of thymus
0.000 0.286 0.714
E31 Polyglandular dysfunction
0.000 0.286 0.714
E30 Disorders of puberty, not elsewhere classified
0.000 0.286 0.714
E10.6 With other specified complications
0.000 0.286 0.714
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.000 0.287 0.713
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.287 0.713
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.000 0.288 0.712
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.291 0.709
E23.1 Drug-induced hypopituitarism
0.000 0.291 0.709
E05.8 Other thyrotoxicosis
0.000 0.291 0.709
L43.8 Other lichen planus
0.000 0.294 0.706
L42 Pityriasis rosea
0.000 0.294 0.705
G37.5 Concentric sclerosis [Balo]
0.705 0.295 0.000
G37.4 Subacute necrotising myelitis
0.705 0.295 0.000
G37.2 Central pontine myelinolysis
0.705 0.295 0.000
G37.1 Central demyelination of corpus callosum
0.705 0.295 0.000
G37.0 Diffuse sclerosis
0.705 0.295 0.000
L43.9 Lichen planus, unspecified
0.000 0.295 0.705
E79 Disorders of purine and pyrimidine metabolism
0.000 0.296 0.704
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.296 0.704
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.300 0.700
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.302 0.698
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.302 0.698
E11.0 With coma
0.000 0.303 0.697
D09 Carcinoma in situ of other and unspecified sites
0.000 0.305 0.695
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.000 0.308 0.692
E77 Disorders of glycoprotein metabolism
0.000 0.309 0.691
E76 Disorders of glycosaminoglycan metabolism
0.000 0.309 0.691
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.309 0.691
E70 Disorders of aromatic amino-acid metabolism
0.000 0.309 0.691
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.309 0.691
M06.8 Other specified rheumatoid arthritis
0.000 0.309 0.691
D04.7 Skin of lower limb, including hip
0.000 0.309 0.691
E03.8 Other specified hypothyroidism
0.000 0.310 0.690
C91 Lymphoid leukaemia
0.000 0.312 0.688
E27.9 Disorder of adrenal gland, unspecified
0.000 0.314 0.686
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.317 0.683
E11.7 With multiple complications
0.000 0.317 0.683
E03.1 Congenital hypothyroidism without goitre
0.000 0.317 0.683
E28.2 Polycystic ovarian syndrome
0.000 0.318 0.682
E89.3 Postprocedural hypopituitarism
0.000 0.318 0.682
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.319 0.681
E20 Hypoparathyroidism
0.000 0.321 0.679
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.321 0.679
L44 Other papulosquamous disorders
0.000 0.321 0.679
L41 Parapsoriasis
0.000 0.321 0.679
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.321 0.679
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.321 0.679
E11.8 With unspecified complications
0.000 0.323 0.677
D46 Myelodysplastic syndromes
0.000 0.328 0.672
D01 Carcinoma in situ of other and unspecified digestive organs
0.000 0.331 0.669
D04.2 Skin of ear and external auricular canal
0.000 0.331 0.669
D04.4 Skin of scalp and neck
0.000 0.331 0.669
E10.4 With neurological complications
0.000 0.332 0.668
M12 Other specific arthropathies
0.000 0.332 0.667
E27.5 Adrenomedullary hyperfunction
0.000 0.333 0.666
E27.0 Other adrenocortical overactivity
0.000 0.333 0.666
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.000 0.334 0.666
G36.0 Neuromyelitis optica [Devic]
0.665 0.334 0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.335 0.665
L57.5 Actinic granuloma
0.000 0.335 0.665
L57.3 Poikiloderma of Civatte
0.000 0.335 0.665
L57.2 Cutis rhomboidalis nuchae
0.000 0.335 0.665
L57.1 Actinic reticuloid
0.000 0.335 0.665
E78.4 Other hyperlipidaemia
0.000 0.340 0.660
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.000 0.341 0.659
E25 Adrenogenital disorders
0.000 0.343 0.657
E89.4 Postprocedural ovarian failure
0.000 0.345 0.655
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.346 0.654
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.000 0.349 0.651
M10.0 Idiopathic gout
0.000 0.350 0.650
M10.9 Gout, unspecified
0.000 0.350 0.650
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.648 0.352 0.000
D04.9 Skin, unspecified
0.000 0.352 0.648
C43 Malignant melanoma of skin
0.000 0.353 0.647
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.000 0.355 0.645
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.356 0.644
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.358 0.642
C83.1 Small cleaved cell (diffuse)
0.000 0.359 0.640
C83.7 Burkitt's tumour
0.000 0.363 0.637
E29.1 Testicular hypofunction
0.000 0.363 0.637
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.364 0.636
E88.8 Other specified metabolic disorders
0.000 0.366 0.634
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.368 0.632
E89.5 Postprocedural testicular hypofunction
0.000 0.368 0.632
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.368 0.632
E04.9 Non-toxic goitre, unspecified
0.000 0.369 0.631
L55 Sunburn
0.000 0.370 0.630
M05.2 Rheumatoid vasculitis
0.000 0.370 0.630
C82.0 Small cleaved cell, follicular
0.000 0.370 0.630
E06.5 Other chronic thyroiditis
0.000 0.374 0.626
E06.4 Drug-induced thyroiditis
0.000 0.374 0.626
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.374 0.626
E06.0 Acute thyroiditis
0.000 0.374 0.626
E04.2 Non-toxic multinodular goitre
0.000 0.375 0.625
E06.9 Thyroiditis, unspecified
0.000 0.376 0.623
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.378 0.622
E27.8 Other specified disorders of adrenal gland
0.000 0.380 0.620
C84 Peripheral and cutaneous T-cell lymphomas
0.000 0.380 0.620
D47.1 Chronic myeloproliferative disease
0.000 0.382 0.618
D47.2 Monoclonal gammopathy
0.000 0.383 0.617
E11.6 With other specified complications
0.000 0.383 0.617
C02 Malignant neoplasm of other and unspecified parts of tongue
0.000 0.385 0.615
E78.3 Hyperchylomicronaemia
0.000 0.386 0.614
E13.9 Without complications
0.000 0.386 0.614
D03 Melanoma in situ
0.000 0.386 0.614
M06.34 Rheumatoid nodule (Hand)
0.000 0.387 0.613
C43.3 Malignant melanoma of other and unspecified parts of face
0.000 0.389 0.611
E89.1 Postprocedural hypoinsulinaemia
0.000 0.389 0.610
E80.4 Gilbert's syndrome
0.000 0.390 0.610
M11 Other crystal arthropathies
0.000 0.390 0.609
E89.2 Postprocedural hypoparathyroidism
0.000 0.391 0.609
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.000 0.391 0.609
D02 Carcinoma in situ of middle ear and respiratory system
0.000 0.393 0.606
C91.9 Lymphoid leukaemia, unspecified
0.000 0.395 0.605
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.396 0.604
C94 Other leukaemias of specified cell type
0.000 0.396 0.604
E72 Other disorders of amino-acid metabolism
0.000 0.396 0.604
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.397 0.603
L43.3 Subacute (active) lichen planus
0.000 0.397 0.602
L43.2 Lichenoid drug reaction
0.000 0.397 0.602
L43.1 Bullous lichen planus
0.000 0.397 0.602
L43.0 Hypertrophic lichen planus
0.000 0.397 0.602
E74 Other disorders of carbohydrate metabolism
0.000 0.400 0.600
D06.0 Endocervix
0.000 0.400 0.600
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.401 0.599
E73 Lactose intolerance
0.000 0.404 0.596
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.000 0.404 0.596
C85.0 Lymphosarcoma
0.000 0.404 0.596
D04.8 Skin of other sites
0.000 0.404 0.595
D04.0 Skin of lip
0.000 0.404 0.595
E88.2 Lipomatosis, not elsewhere classified
0.000 0.406 0.594
D06.7 Other parts of cervix
0.000 0.406 0.594
D06.1 Exocervix
0.000 0.406 0.594
E24.0 Pituitary-dependent Cushing's disease
0.000 0.406 0.594
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.409 0.591
E88.9 Metabolic disorder, unspecified
0.000 0.409 0.591
C86 Other specified types of T/NK-cell lymphoma
0.000 0.411 0.589
L56.9 Acute skin change due to ultraviolet radiation, unspecified
0.000 0.411 0.589
C93 Monocytic leukaemia
0.000 0.411 0.588
C83.6 Undifferentiated (diffuse)
0.000 0.413 0.587
C83.5 Lymphoblastic (diffuse)
0.000 0.413 0.587
C83.4 Immunoblastic (diffuse)
0.000 0.413 0.587
C83.2 Mixed small and large cell (diffuse)
0.000 0.413 0.587
M10.4 Other secondary gout
0.000 0.414 0.586
M10.2 Drug-induced gout
0.000 0.414 0.586
M10.1 Lead-induced gout
0.000 0.414 0.586
C12 Malignant neoplasm of pyriform sinus
0.000 0.414 0.586
C88 Malignant immunoproliferative diseases
0.000 0.417 0.583
E04.8 Other specified non-toxic goitre
0.000 0.417 0.583
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.417 0.583
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.418 0.582
E85 Amyloidosis
0.000 0.419 0.581
E28.9 Ovarian dysfunction, unspecified
0.000 0.422 0.578
E28.8 Other ovarian dysfunction
0.000 0.422 0.578
E28.1 Androgen excess
0.000 0.422 0.578
E28.0 Oestrogen excess
0.000 0.422 0.578
L58 Radiodermatitis
0.000 0.422 0.578
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.423 0.577
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.423 0.577
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.423 0.577
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.423 0.577
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.423 0.577
E24.9 Cushing's syndrome, unspecified
0.000 0.423 0.577
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.000 0.423 0.576
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.424 0.576
M06.38 Rheumatoid nodule (Other)
0.000 0.424 0.576
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.424 0.576
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.424 0.576
M06.33 Rheumatoid nodule (Forearm)
0.000 0.424 0.576
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.424 0.576
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.424 0.576
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.000 0.424 0.576
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.425 0.575
G36.9 Acute disseminated demyelination, unspecified
0.574 0.426 0.000
G36.8 Other specified acute disseminated demyelination
0.574 0.426 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.574 0.426 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.000 0.426 0.573
D43.2 Brain, unspecified
0.000 0.427 0.573
C07 Malignant neoplasm of parotid gland
0.000 0.430 0.570
M10.3 Gout due to impairment of renal function
0.000 0.430 0.570
M10.90 Gout, unspecified (Multiple sites)
0.000 0.431 0.569
D09.0 Bladder
0.000 0.432 0.568
M14 Arthropathies in other diseases classified elsewhere
0.000 0.432 0.567
E29.9 Testicular dysfunction, unspecified
0.000 0.436 0.564
E29.8 Other testicular dysfunction
0.000 0.436 0.564
E29.0 Testicular hyperfunction
0.000 0.436 0.564
D43.4 Spinal cord
0.000 0.439 0.561
D48.5 Skin
0.000 0.439 0.561
E84.9 Cystic fibrosis, unspecified
0.000 0.440 0.560
E24.2 Drug-induced Cushing's syndrome
0.000 0.441 0.558
E26.0 Primary hyperaldosteronism
0.000 0.442 0.558
D01.0 Colon
0.000 0.442 0.558
E88.3 Tumour lysis syndrome
0.000 0.442 0.557
E28.3 Primary ovarian failure
0.000 0.443 0.557
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.000 0.443 0.557
E13.8 With unspecified complications
0.000 0.444 0.556
E13.7 With multiple complications
0.000 0.444 0.556
E13.6 With other specified complications
0.000 0.444 0.556
E13.5 With peripheral circulatory complications
0.000 0.444 0.556
E13.4 With neurological complications
0.000 0.444 0.556
E13.3 With ophthalmic complications
0.000 0.444 0.556
E13.2 With renal complications
0.000 0.444 0.556
E13.1 With ketoacidosis
0.000 0.444 0.556
E13.0 With coma
0.000 0.444 0.556
E24.8 Other Cushing's syndrome
0.000 0.445 0.555
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.445 0.555
E24.3 Ectopic ACTH syndrome
0.000 0.445 0.555
E24.1 Nelson's syndrome
0.000 0.445 0.555
C82.2 Large cell, follicular
0.000 0.446 0.554
D46.2 Refractory anaemia with excess of blasts
0.000 0.446 0.554
C03 Malignant neoplasm of gum
0.000 0.447 0.552
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.448 0.552
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.448 0.552
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.448 0.552
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.448 0.552
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.448 0.552
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.448 0.552
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.448 0.552
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.448 0.552
E78.8 Other disorders of lipoprotein metabolism
0.000 0.448 0.552
L57.4 Cutis laxa senilis
0.000 0.450 0.550
C02.9 Tongue, unspecified
0.000 0.452 0.548
C95 Leukaemia of unspecified cell type
0.000 0.452 0.547
D46.9 Myelodysplastic syndrome, unspecified
0.000 0.456 0.544
E11.5 With peripheral circulatory complications
0.000 0.457 0.543
E27.2 Addisonian crisis
0.000 0.458 0.542
E80.1 Porphyria cutanea tarda
0.000 0.458 0.542
C90 Multiple myeloma and malignant plasma cell neoplasms
0.000 0.460 0.540
C91.5 Adult T-cell leukaemia
0.000 0.461 0.539
C08 Malignant neoplasm of other and unspecified major salivary glands
0.000 0.461 0.538
E80.6 Other disorders of bilirubin metabolism
0.000 0.463 0.537
D40.0 Prostate
0.000 0.463 0.537
L10-L14 Bullous disorders
0.000 0.464 0.536
D43.9 Central nervous system, unspecified
0.000 0.465 0.534
D43.7 Other parts of central nervous system
0.000 0.465 0.534
D43.3 Cranial nerves
0.000 0.465 0.534
E26.9 Hyperaldosteronism, unspecified
0.000 0.469 0.531
E26.8 Other hyperaldosteronism
0.000 0.469 0.531
E26.1 Secondary hyperaldosteronism
0.000 0.469 0.531
M13 Other arthritis
0.000 0.469 0.531
D09.1 Other and unspecified urinary organs
0.000 0.470 0.530
C91.4 Hairy-cell leukaemia
0.000 0.471 0.529
M10.09 Idiopathic gout (Site unspecified)
0.000 0.471 0.528
D04.6 Skin of upper limb, including shoulder
0.000 0.472 0.528
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.474 0.526
E80.5 Crigler-Najjar syndrome
0.000 0.474 0.526
E80.3 Defects of catalase and peroxydase
0.000 0.474 0.526
E80.0 Hereditary erythropoietic porphyria
0.000 0.474 0.526
C81 Hodgkin's disease
0.000 0.474 0.526
E21.4 Other specified disorders of parathyroid gland
0.000 0.475 0.525
C02.1 Border of tongue
0.000 0.475 0.525
D43.1 Brain, infratentorial
0.000 0.476 0.524
E21.3 Hyperparathyroidism, unspecified
0.000 0.477 0.523
D04.1 Skin of eyelid, including canthus
0.000 0.477 0.523
E84.8 Cystic fibrosis with other manifestations
0.000 0.477 0.522
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.477 0.522
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.477 0.522
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified
0.000 0.478 0.522
D47.3 Essential (haemorrhagic) thrombocythaemia
0.000 0.478 0.522
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.000 0.479 0.521
C11 Malignant neoplasm of nasopharynx
0.000 0.479 0.520
D00.1 Oesophagus
0.000 0.481 0.519
C75 Malignant neoplasm of other endocrine glands and related structures
0.000 0.482 0.518
E40-E46 Malnutrition
0.000 0.482 0.517
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.483 0.517
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.483 0.517
D03.5 Melanoma in situ of trunk
0.000 0.483 0.517
L56.8 Other specified acute skin changes due to ultraviolet radiation
0.000 0.485 0.515
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
M08.9 Juvenile arthritis, unspecified
0.000 0.486 0.514
M08.8 Other juvenile arthritis
0.000 0.486 0.514
M08.4 Pauciarticular juvenile arthritis
0.000 0.486 0.514
M08.3 Juvenile polyarthritis (seronegative)
0.000 0.486 0.514
M08.2 Juvenile arthritis with systemic onset
0.000 0.486 0.514
M08.1 Juvenile ankylosing spondylitis
0.000 0.486 0.514
M08.0 Juvenile rheumatoid arthritis
0.000 0.486 0.514
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.000 0.486 0.514
M09.2 Juvenile arthritis in ulcerative colitis
0.000 0.486 0.514
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.000 0.486 0.514
M09.0 Juvenile arthritis in psoriasis
0.000 0.486 0.514
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.486 0.514
M06.18 Adult-onset Still's disease (Other)
0.000 0.486 0.514
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.486 0.514
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.486 0.514
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.486 0.514
M06.14 Adult-onset Still's disease (Hand)
0.000 0.486 0.514
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.486 0.514
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.486 0.514
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.486 0.514
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.486 0.514
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.486 0.514
M06.28 Rheumatoid bursitis (Other)
0.000 0.486 0.514
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.486 0.514
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.486 0.514
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.486 0.514
M06.24 Rheumatoid bursitis (Hand)
0.000 0.486 0.514
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.486 0.514
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.486 0.514
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.486 0.514
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)
0.000 0.486 0.514
M07.08 Distal interphalangeal proriatic arthropathy-Other
0.000 0.486 0.514
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)
0.000 0.486 0.514
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg
0.000 0.486 0.514
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh
0.000 0.486 0.514
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)
0.000 0.486 0.514
M07.03 Distal interphalangeal proriatic arthropathy-Forearm
0.000 0.486 0.514
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm
0.000 0.486 0.514
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region
0.000 0.486 0.514
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)
0.000 0.486 0.514
M07.19 Arthritis mutilans (Site unspecified)
0.000 0.486 0.514
M07.18 Arthritis mutilans (Other)
0.000 0.486 0.514
M07.17 Arthritis mutilans (Ankle and foot)
0.000 0.486 0.514
M07.16 Arthritis mutilans (Lower leg)
0.000 0.486 0.514
M07.15 Arthritis mutilans (Pelvic region and thigh)
0.000 0.486 0.514
M07.14 Arthritis mutilans (Hand)
0.000 0.486 0.514
M07.13 Arthritis mutilans (Forearm)
0.000 0.486 0.514
M07.12 Arthritis mutilans (Upper arm)
0.000 0.486 0.514

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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