TreeWAS – Variant ID: rs201958930

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Chapter IX Diseases of the circulatory system	0.976	0.024	0.000
I20-I25 Ischaemic heart diseases	0.976	0.024	0.000
I30-I52 Other forms of heart disease	0.976	0.024	0.000
I20 Angina pectoris	0.957	0.043	0.000
I51 Complications and ill-defined descriptions of heart disease	0.954	0.046	0.000
I25 Chronic ischaemic heart disease	0.948	0.052	0.000
I51.7 Cardiomegaly	0.925	0.075	0.000
I34 Nonrheumatic mitral valve disorders	0.918	0.082	0.000
I20.9 Angina pectoris, unspecified	0.910	0.090	0.000
I25.1 Atherosclerotic heart disease	0.900	0.100	0.000
# Top node	0.872	0.128	0.000
I20.0 Unstable angina	0.866	0.134	0.000
Chapter XIV Diseases of the genitourinary system	0.860	0.140	0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.851	0.149	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.849	0.151	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.839	0.161	0.000
Chapter V Mental and behavioural disorders	0.838	0.162	0.000
N10-N16 Renal tubulo-interstitial diseases	0.832	0.168	0.000
I49 Other cardiac arrhythmias	0.818	0.182	0.000
I34.1 Mitral (valve) prolapse	0.818	0.182	0.000
I34.0 Mitral (valve) insufficiency	0.813	0.187	0.000
N80-N98 Noninflammatory disorders of female genital tract	0.810	0.190	0.000
I80 Phlebitis and thrombophlebitis	0.809	0.191	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.805	0.195	0.000
S80-S89 Injuries to the knee and lower leg	0.803	0.197	0.000
I21 Acute myocardial infarction	0.796	0.204	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.791	0.209	0.000
I31 Other diseases of pericardium	0.786	0.214	0.000
I25.5 Ischaemic cardiomyopathy	0.773	0.227	0.000
N13 Obstructive and reflux uropathy	0.773	0.227	0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.773	0.227	0.000
M50-M54 Other dorsopathies	0.772	0.228	0.000
I51.9 Heart disease, unspecified	0.772	0.228	0.000
N85 Other noninflammatory disorders of uterus, except cervix	0.770	0.230	0.000
I45 Other conduction disorders	0.768	0.232	0.000
N60-N64 Disorders of breast	0.764	0.236	0.000
I24 Other acute ischaemic heart diseases	0.759	0.241	0.000
M51 Other intervertebral disk disorders	0.752	0.248	0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.752	0.248	0.000
I35 Nonrheumatic aortic valve disorders	0.749	0.251	0.000
I22 Subsequent myocardial infarction	0.748	0.252	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.746	0.254	0.000
I51.8 Other ill-defined heart diseases	0.743	0.257	0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.737	0.263	0.000
I25.2 Old myocardial infarction	0.737	0.263	0.000
M51.2 Other specified intervertebral disk displacement	0.733	0.267	0.000
N85.8 Other specified noninflammatory disorders of uterus	0.731	0.269	0.000
I42 Cardiomyopathy	0.729	0.270	0.000
S60-S69 Injuries to the wrist and hand	0.723	0.277	0.000
N84 Polyp of female genital tract	0.721	0.279	0.000
N95 Menopausal and other perimenopausal disorders	0.721	0.279	0.000
I20.8 Other forms of angina pectoris	0.720	0.280	0.000
I95 Hypotension	0.719	0.281	0.000
Chapter XXI Factors influencing health status and contact with health services	0.716	0.284	0.000
Chapter XX External causes of morbidity and mortality	0.714	0.286	0.000
I33 Acute and subacute endocarditis	0.714	0.286	0.000
Z00-Z13 Persons encountering health services for examination and investigation	0.713	0.287	0.000
I44 Atrioventricular and left bundle-branch block	0.710	0.290	0.000
N17-N19 Renal failure	0.709	0.291	0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms	0.708	0.292	0.000
I47 Paroxysmal tachycardia	0.707	0.292	0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.705	0.295	0.000
N85.4 Malposition of uterus	0.704	0.296	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.702	0.298	0.000
I00-I02 Acute rheumatic fever	0.700	0.300	0.000
I23 Certain current complications following acute myocardial infarction	0.700	0.300	0.000
I52 Other heart disorders in diseases classified elsewhere	0.699	0.300	0.000
I48 Atrial fibrillation and flutter	0.699	0.300	0.000
I43 Cardiomyopathy in diseases classified elsewhere	0.699	0.300	0.000
I41 Myocarditis in diseases classified elsewhere	0.699	0.300	0.000
I40 Acute myocarditis	0.699	0.300	0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.699	0.300	0.000
I37 Pulmonary valve disorders	0.699	0.300	0.000
I36 Nonrheumatic tricuspid valve disorders	0.699	0.300	0.000
I32 Pericarditis in diseases classified elsewhere	0.699	0.300	0.000
I30 Acute pericarditis	0.699	0.300	0.000
N93 Other abnormal uterine and vaginal bleeding	0.697	0.303	0.000
F10 Mental and behavioural disorders due to use of alcohol	0.697	0.303	0.000
I38 Endocarditis, valve unspecified	0.695	0.305	0.000
I46 Cardiac arrest	0.692	0.308	0.000
S81 Open wound of lower leg	0.688	0.312	0.000
I20.1 Angina pectoris with documented spasm	0.686	0.314	0.000
I51.6 Cardiovascular disease, unspecified	0.684	0.316	0.000
I51.5 Myocardial degeneration	0.684	0.316	0.000
I51.4 Myocarditis, unspecified	0.684	0.316	0.000
I51.3 Intracardiac thrombosis, not elsewhere classified	0.684	0.316	0.000
I51.2 Rupture of papillary muscle, not elsewhere classified	0.684	0.316	0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.684	0.316	0.000
I51.0 Cardiac septal defect, acquired	0.684	0.316	0.000
I25.6 Silent myocardial ischaemia	0.680	0.320	0.000
I25.4 Coronary artery aneurysm	0.680	0.320	0.000
I25.3 Aneurysm of heart	0.680	0.320	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.680	0.320	0.000
Z09.0 Follow-up examination after surgery for other conditions	0.678	0.322	0.000
M54 Dorsalgia	0.677	0.323	0.000
T66-T78 Other and unspecified effects of external causes	0.676	0.324	0.000
S40-S49 Injuries to the shoulder and upper arm	0.674	0.326	0.000
I49.8 Other specified cardiac arrhythmias	0.673	0.326	0.000
S82 Fracture of lower leg, including ankle	0.673	0.327	0.000
N13.3 Other and unspecified hydronephrosis	0.668	0.332	0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle	0.667	0.333	0.000
I87 Other disorders of veins	0.667	0.333	0.000
N64 Other disorders of breast	0.667	0.333	0.000
I05-I09 Chronic rheumatic heart diseases	0.665	0.335	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.665	0.335	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.664	0.336	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.664	0.336	0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.661	0.339	0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.658	0.341	0.000
I34.8 Other nonrheumatic mitral valve disorders	0.658	0.341	0.000
I34.2 Nonrheumatic mitral (valve) stenosis	0.658	0.341	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.656	0.344	0.000
I31.3 Pericardial effusion (noninflammatory)	0.656	0.344	0.000
I99 Other and unspecified disorders of circulatory system	0.653	0.347	0.000
I45.6 Preexcitation syndrome	0.649	0.351	0.000
N95.2 Postmenopausal atrophic vaginitis	0.647	0.353	0.000
N88 Other noninflammatory disorders of cervix uteri	0.645	0.355	0.000
I21.9 Acute myocardial infarction, unspecified	0.644	0.356	0.000
Z03 Medical observation and evaluation for suspected diseases and conditions	0.644	0.356	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.642	0.358	0.000
Chapter XXII Codes for special purposes	0.642	0.358	0.000
F60-F69 Disorders of adult personality and behaviour	0.641	0.359	0.000
S90-S99 Injuries to the ankle and foot	0.640	0.360	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.640	0.360	0.000
Z09.9 Follow-up examination after unspecified treatment for other conditions	0.637	0.363	0.000
F40 Phobic anxiety disorders	0.636	0.364	0.000
N84.1 Polyp of cervix uteri	0.634	0.366	0.000
S70-S79 Injuries to the hip and thigh	0.632	0.368	0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.629	0.371	0.000
I49.3 Ventricular premature depolarisation	0.628	0.371	0.000
I80.8 Phlebitis and thrombophlebitis of other sites	0.627	0.373	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.626	0.373	0.000
F10.1 Harmful use	0.626	0.374	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.626	0.374	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.625	0.375	0.000
I95.9 Hypotension, unspecified	0.624	0.376	0.000
N81 Female genital prolapse	0.624	0.376	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.624	0.376	0.000
I49.5 Sick sinus syndrome	0.624	0.376	0.000
M45-M49 Spondylopathies	0.624	0.376	0.000
F30-F39 Mood [affective] disorders	0.623	0.377	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.621	0.379	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.619	0.381	0.000
I50 Heart failure	0.618	0.382	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.617	0.383	0.000
N70-N77 Inflammatory diseases of female pelvic organs	0.615	0.385	0.001
I95.8 Other hypotension	0.615	0.385	0.000
I22.8 Subsequent myocardial infarction of other sites	0.614	0.386	0.000
N60 Benign mammary dysplasia	0.614	0.386	0.000
N84.8 Polyp of other parts of female genital tract	0.613	0.387	0.000
Chapter VIII Diseases of the ear and mastoid process	0.612	0.387	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.612	0.388	0.000
I88 Nonspecific lymphadenitis	0.610	0.390	0.000
I86 Varicose veins of other sites	0.610	0.390	0.000
I82 Other venous embolism and thrombosis	0.610	0.390	0.000
I81 Portal vein thrombosis	0.610	0.390	0.000
N94.6 Dysmenorrhoea, unspecified	0.609	0.391	0.000
T79-T79 Certain early complications of trauma	0.608	0.391	0.000
T33-T35 Frostbite	0.608	0.391	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.608	0.391	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.608	0.391	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.608	0.391	0.000
T00-T07 Injuries involving multiple body regions	0.608	0.391	0.000
S10-S19 Injuries to the neck	0.608	0.391	0.000
Z09.2 Follow-up examination after chemotherapy for other conditions	0.608	0.392	0.000
N90 Other noninflammatory disorders of vulva and perineum	0.607	0.393	0.000
F10.2 Dependence syndrome	0.606	0.394	0.000
S61 Open wound of wrist and hand	0.605	0.395	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.605	0.395	0.000
N40-N51 Diseases of male genital organs	0.604	0.396	0.000
N89 Other noninflammatory disorders of vagina	0.603	0.397	0.000
F41 Other anxiety disorders	0.602	0.398	0.000
N13.5 Kinking and stricture of ureter without hydronephrosis	0.602	0.398	0.000
S82.8 Fractures of other parts of lower leg	0.602	0.398	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.601	0.399	0.000
F99-F99 Unspecified mental disorder	0.601	0.399	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.601	0.399	0.000
F80-F89 Disorders of psychological development	0.601	0.399	0.000
F70-F79 Mental retardation	0.601	0.399	0.000
S80 Superficial injury of lower leg	0.600	0.400	0.000
M51.9 Intervertebral disk disorder, unspecified	0.600	0.400	0.000
W00-W19 Falls	0.599	0.401	0.000
I44.2 Atrioventricular block, complete	0.598	0.402	0.000
I35.0 Aortic (valve) stenosis	0.598	0.402	0.000
T51 Toxic effect of alcohol	0.597	0.403	0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.596	0.403	0.000
N15 Other renal tubulo-interstitial diseases	0.596	0.403	0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.596	0.403	0.000
N11 Chronic tubulo-interstitial nephritis	0.596	0.403	0.000
N10 Acute tubulo-interstitial nephritis	0.596	0.403	0.000
S89 Other and unspecified injuries of lower leg	0.595	0.405	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.593	0.407	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.592	0.408	0.000
S81.8 Open wound of other parts of lower leg	0.591	0.409	0.000
I45.9 Conduction disorder, unspecified	0.589	0.411	0.000
N93.8 Other specified abnormal uterine and vaginal bleeding	0.589	0.411	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.588	0.411	0.000
N95.8 Other specified menopausal and perimenopausal disorders	0.588	0.412	0.000
N17 Acute renal failure	0.588	0.412	0.000
I49.4 Other and unspecified premature depolarisation	0.587	0.413	0.000
I49.2 Junctional premature depolarisation	0.587	0.413	0.000
I49.1 Atrial premature depolarisation	0.587	0.413	0.000
I49.0 Ventricular fibrillation and flutter	0.587	0.413	0.000
I89.1 Lymphangitis	0.585	0.415	0.000
N18 Chronic renal failure	0.583	0.417	0.000
S62 Fracture at wrist and hand level	0.582	0.418	0.000
N98 Complications associated with artificial fertilisation	0.581	0.419	0.000
N91 Absent, scanty and rare menstruation	0.581	0.419	0.000
N82 Fistulae involving female genital tract	0.581	0.419	0.000
N96 Habitual aborter	0.581	0.419	0.000
N61 Inflammatory disorders of breast	0.580	0.420	0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.580	0.420	0.000
Z03.8 Observation for other suspected diseases and conditions	0.580	0.420	0.000
M65-M68 Disorders of synovium and tendon	0.580	0.420	0.000
Z03.4 Observation for suspected myocardial infarction	0.580	0.420	0.000
N99-N99 Other disorders of the genitourinary system	0.579	0.421	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.578	0.422	0.000
S20-S29 Injuries to the thorax	0.577	0.423	0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.577	0.423	0.000
M86-M90 Other osteopathies	0.576	0.423	0.000
S88 Traumatic amputation of lower leg	0.576	0.424	0.000
S87 Crushing injury of lower leg	0.576	0.424	0.000
S86 Injury of muscle and tendon at lower leg level	0.576	0.424	0.000
S85 Injury of blood vessels at lower leg level	0.576	0.424	0.000
S84 Injury of nerves at lower leg level	0.576	0.424	0.000
N64.5 Other signs and symptoms in breast	0.574	0.426	0.000
S42 Fracture of shoulder and upper arm	0.571	0.429	0.000
F41.2 Mixed anxiety and depressive disorder	0.571	0.429	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.571	0.429	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.571	0.429	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.571	0.429	0.000
I35.2 Aortic (valve) stenosis with insufficiency	0.571	0.429	0.000
Z13 Special screening examination for other diseases and disorders	0.570	0.430	0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis	0.569	0.431	0.000
M91-M94 Chondropathies	0.567	0.433	0.000
M60-M63 Disorders of muscles	0.567	0.433	0.000
M00-M03 Infectious arthropathies	0.567	0.433	0.000
M54.5 Low back pain	0.566	0.434	0.000
S83.2 Tear of meniscus, current	0.566	0.434	0.000
N62 Hypertrophy of breast	0.565	0.435	0.000
I31.8 Other specified diseases of pericardium	0.564	0.436	0.000
I31.2 Haemopericardium, not elsewhere classified	0.564	0.436	0.000
I31.1 Chronic constrictive pericarditis	0.564	0.436	0.000
I31.0 Chronic adhesive pericarditis	0.564	0.436	0.000
W20-W49 Exposure to inanimate mechanical forces	0.563	0.437	0.000
F43 Reaction to severe stress, and adjustment disorders	0.562	0.438	0.000
M40-M43 Deforming dorsopathies	0.560	0.440	0.000
I83 Varicose veins of lower extremities	0.560	0.440	0.000
X60-X84 Intentional self-harm	0.560	0.440	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.559	0.441	0.000
F10.4 Withdrawal state with delirium	0.557	0.443	0.000
N88.2 Stricture and stenosis of cervix uteri	0.557	0.443	0.000
F40.2 Specific (isolated) phobias	0.556	0.444	0.000
I49.9 Cardiac arrhythmia, unspecified	0.556	0.444	0.000
S60 Superficial injury of wrist and hand	0.556	0.444	0.000
I31.9 Disease of pericardium, unspecified	0.555	0.444	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.554	0.445	0.000
N13.9 Obstructive and reflux uropathy, unspecified	0.554	0.446	0.000
N13.8 Other obstructive and reflux uropathy	0.554	0.446	0.000
N13.7 Vesicoureteral-reflux-associated uropathy	0.554	0.446	0.000
N13.6 Pyonephrosis	0.554	0.446	0.000
N13.4 Hydroureter	0.554	0.446	0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.554	0.446	0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.554	0.446	0.000
M53 Other dorsopathies, not elsewhere classified	0.553	0.447	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.553	0.447	0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.553	0.447	0.000
N81.8 Other female genital prolapse	0.553	0.447	0.000
T78 Adverse effects, not elsewhere classified	0.552	0.447	0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.552	0.448	0.000
N85.9 Noninflammatory disorder of uterus, unspecified	0.552	0.448	0.000
N85.7 Haematometra	0.552	0.448	0.000
N85.6 Intra-uterine synechiae	0.552	0.448	0.000
N85.5 Inversion of uterus	0.552	0.448	0.000
N85.3 Subinvolution of uterus	0.552	0.448	0.000
N85.1 Endometrial adenomatous hyperplasia	0.552	0.448	0.000
I45.8 Other specified conduction disorders	0.551	0.449	0.000
I45.5 Other specified heart block	0.551	0.449	0.000
I45.4 Nonspecific intraventricular block	0.551	0.449	0.000
I45.3 Trifascicular block	0.551	0.449	0.000
I45.2 Bifascicular block	0.551	0.449	0.000
I45.0 Right fascicular block	0.551	0.449	0.000
M20-M25 Other joint disorders	0.551	0.449	0.000
S82.80 Fractures of other parts of lower leg (closed)	0.551	0.449	0.000
M54.9 Dorsalgia, unspecified	0.549	0.451	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.547	0.453	0.000
I42.9 Cardiomyopathy, unspecified	0.547	0.453	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.546	0.454	0.000
M80-M85 Disorders of bone density and structure	0.546	0.454	0.000
I24.1 Dressler's syndrome	0.544	0.455	0.000
N42 Other disorders of prostate	0.544	0.456	0.000
N00-N08 Glomerular diseases	0.542	0.458	0.000
N97 Female infertility	0.542	0.458	0.000
Z09.8 Follow-up examination after other treatment for other conditions	0.540	0.460	0.000
F20 Schizophrenia	0.540	0.460	0.000
S50-S59 Injuries to the elbow and forearm	0.540	0.460	0.000
M51.3 Other specified intervertebral disk degeneration	0.539	0.461	0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy	0.539	0.461	0.000
M51.8 Other specified intervertebral disk disorders	0.539	0.461	0.000
M51.4 Schmorl's nodes	0.539	0.461	0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy	0.539	0.461	0.000
N93.9 Abnormal uterine and vaginal bleeding, unspecified	0.537	0.463	0.000
I35.9 Aortic valve disorder, unspecified	0.537	0.463	0.000
I35.8 Other aortic valve disorders	0.537	0.463	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.537	0.463	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.536	0.464	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.536	0.464	0.000
I85 Oesophageal varices	0.536	0.464	0.000
S00-S09 Injuries to the head	0.536	0.464	0.000
F48 Other neurotic disorders	0.535	0.465	0.000
F45 Somatoform disorders	0.535	0.465	0.000
F44 Dissociative [conversion] disorders	0.535	0.465	0.000
F42 Obsessive-compulsive disorder	0.535	0.465	0.000
I87.2 Venous insufficiency (chronic) (peripheral)	0.534	0.465	0.000
I47.1 Supraventricular tachycardia	0.534	0.466	0.000
I42.0 Dilated cardiomyopathy	0.530	0.470	0.000
I89.0 Lymphoedema, not elsewhere classified	0.530	0.470	0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.528	0.471	0.000
F18 Mental and behavioural disorders due to use of volatile solvents	0.528	0.471	0.000
F16 Mental and behavioural disorders due to use of hallucinogens	0.528	0.471	0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.528	0.471	0.000
F14 Mental and behavioural disorders due to use of cocaine	0.528	0.471	0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.528	0.471	0.000
F12 Mental and behavioural disorders due to use of cannabinoids	0.528	0.471	0.000
F11 Mental and behavioural disorders due to use of opioids	0.528	0.471	0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis	0.527	0.473	0.000
I33.0 Acute and subacute infective endocarditis	0.526	0.473	0.000
N64.8 Other specified disorders of breast	0.525	0.475	0.000
I50.0 Congestive heart failure	0.523	0.477	0.000
I42.8 Other cardiomyopathies	0.523	0.477	0.000
I42.7 Cardiomyopathy due to drugs and other external agents	0.523	0.477	0.000
I42.6 Alcoholic cardiomyopathy	0.523	0.477	0.000
I42.5 Other restrictive cardiomyopathy	0.523	0.477	0.000
I42.4 Endocardial fibroelastosis	0.523	0.477	0.000
I42.3 Endomyocardial (eosinophilic) disease	0.523	0.477	0.000
I42.2 Other hypertrophic cardiomyopathy	0.523	0.477	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.523	0.477	0.000
S81.0 Open wound of knee	0.522	0.478	0.000
T51.0 Ethanol	0.522	0.478	0.000
N30-N39 Other diseases of urinary system	0.520	0.480	0.000
N18.9 Chronic renal failure, unspecified	0.519	0.481	0.000
S69 Other and unspecified injuries of wrist and hand	0.519	0.481	0.000
S67 Crushing injury of wrist and hand	0.519	0.481	0.000
S65 Injury of blood vessels at wrist and hand level	0.519	0.481	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.519	0.481	0.000
M54.2 Cervicalgia	0.518	0.482	0.000
I44.1 Atrioventricular block, second degree	0.518	0.482	0.000
N25-N29 Other disorders of kidney and ureter	0.518	0.482	0.000
N84.9 Polyp of female genital tract, unspecified	0.517	0.483	0.000
N84.3 Polyp of vulva	0.517	0.483	0.000
N84.2 Polyp of vagina	0.517	0.483	0.000
N95.9 Menopausal and perimenopausal disorder, unspecified	0.517	0.483	0.000
N95.3 States associated with artificial menopause	0.517	0.483	0.000
N95.1 Menopausal and female climacteric states	0.517	0.483	0.000
V20-V29 Motorcycle rider injured in transport accident	0.517	0.483	0.000
I95.2 Hypotension due to drugs	0.515	0.485	0.000
I95.0 Idiopathic hypotension	0.515	0.485	0.000
N93.0 Postcoital and contact bleeding	0.515	0.485	0.000
Z08 Follow-up examination after treatment for malignant neoplasm	0.514	0.486	0.000
I74 Arterial embolism and thrombosis	0.513	0.486	0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.512	0.487	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.512	0.488	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.512	0.488	0.000
Y35-Y36 Legal intervention and operations of war	0.512	0.488	0.000
Y10-Y34 Event of undetermined intent	0.512	0.488	0.000
Y00-Y09 Assault	0.512	0.488	0.000
X85-X99 Assault	0.512	0.488	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.512	0.488	0.000
X50-X57 Overexertion, travel and privation	0.512	0.488	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.512	0.488	0.000
X30-X39 Exposure to forces of nature	0.512	0.488	0.000
X20-X29 Contact with venomous animals and plants	0.512	0.488	0.000
X10-X19 Contact with heat and hot substances	0.512	0.488	0.000
X00-X09 Exposure to smoke, fire and flames	0.512	0.488	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.512	0.488	0.000
W75-W84 Other accidental threats to breathing	0.512	0.488	0.000
W65-W74 Accidental drowning and submersion	0.512	0.488	0.000
W50-W64 Exposure to animate mechanical forces	0.512	0.488	0.000
V98-V99 Other and unspecified transport accidents	0.512	0.488	0.000
V95-V97 Air and space transport accidents	0.512	0.488	0.000
V90-V94 Water transport accidents	0.512	0.488	0.000
V80-V89 Other land transport accidents	0.512	0.488	0.000
V70-V79 Bus occupant injured in transport accident	0.512	0.488	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.512	0.488	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.512	0.488	0.000
V40-V49 Car occupant injured in transport accident	0.512	0.488	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.512	0.488	0.000
V01-V09 Pedestrian injured in transport accident	0.512	0.488	0.000
I33.9 Acute endocarditis, unspecified	0.512	0.488	0.000
Z10 Routine general health check-up of defined subpopulation	0.511	0.489	0.000
I60-I69 Cerebrovascular diseases	0.510	0.490	0.000
I21.4 Acute subendocardial myocardial infarction	0.510	0.490	0.000
I44.6 Other and unspecified fascicular block	0.509	0.491	0.000
I44.5 Left posterior fascicular block	0.509	0.491	0.000
I44.4 Left anterior fascicular block	0.509	0.491	0.000
I44.3 Other and unspecified atrioventricular block	0.509	0.491	0.000
Z09.7 Follow-up examination after combined treatment for other conditions	0.508	0.492	0.000
Z09.4 Follow-up examination after treatment of fracture	0.508	0.492	0.000
Z09.3 Follow-up examination after psychotherapy	0.508	0.492	0.000
Z09.1 Follow-up examination after radiotherapy for other conditions	0.508	0.492	0.000
I47.9 Paroxysmal tachycardia, unspecified	0.507	0.493	0.000
I47.0 Reentry ventricular arrhythmia	0.507	0.493	0.000
I24.8 Other forms of acute ischaemic heart disease	0.506	0.493	0.000
I46.9 Cardiac arrest, unspecified	0.506	0.494	0.000
F32 Depressive episode	0.506	0.494	0.000
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified	0.505	0.495	0.000
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes	0.505	0.495	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.505	0.495	0.000
S61.8 Open wound of other parts of wrist and hand	0.504	0.496	0.000
T65 Toxic effect of other and unspecified substances	0.503	0.497	0.000
T63 Toxic effect of contact with venomous animals	0.503	0.497	0.000
T62 Toxic effect of other noxious substances eaten as food	0.503	0.497	0.000
T61 Toxic effect of noxious substances eaten as seafood	0.503	0.497	0.000
T60 Toxic effect of pesticides	0.503	0.497	0.000
T59 Toxic effect of other gases, fumes and vapours	0.503	0.497	0.000
T57 Toxic effect of other inorganic substances	0.503	0.497	0.000
T56 Toxic effect of metals	0.503	0.497	0.000
T54 Toxic effect of corrosive substances	0.503	0.497	0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.503	0.497	0.000
T52 Toxic effect of organic solvents	0.503	0.497	0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.503	0.497	0.000
T58 Toxic effect of carbon monoxide	0.503	0.497	0.000
T55 Toxic effect of soaps and detergents	0.503	0.497	0.000
I02 Rheumatic chorea	0.502	0.498	0.000
I01 Rheumatic fever with heart involvement	0.502	0.498	0.000
I00 Rheumatic fever without mention of heart involvement	0.502	0.498	0.000
I23.8 Other current complications following acute myocardial infarction	0.502	0.498	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.502	0.498	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.502	0.498	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.502	0.498	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.502	0.498	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.502	0.498	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.502	0.498	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.502	0.498	0.000
M54.4 Lumbago with sciatica	0.502	0.498	0.000
I30.9 Acute pericarditis, unspecified	0.501	0.498	0.000
I30.8 Other forms of acute pericarditis	0.501	0.498	0.000
I30.1 Infective pericarditis	0.501	0.498	0.000
I30.0 Acute nonspecific idiopathic pericarditis	0.501	0.498	0.000
I32.8 Pericarditis in other diseases classified elsewhere	0.501	0.498	0.000
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.501	0.498	0.000
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.501	0.498	0.000
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.501	0.498	0.000
I36.8 Other nonrheumatic tricuspid valve disorders	0.501	0.498	0.000
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.501	0.498	0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.501	0.498	0.000
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.501	0.498	0.000
I37.9 Pulmonary valve disorder, unspecified	0.501	0.498	0.000
I37.8 Other pulmonary valve disorders	0.501	0.498	0.000
I37.2 Pulmonary valve stenosis with insufficiency	0.501	0.498	0.000
I37.1 Pulmonary valve insufficiency	0.501	0.498	0.000
I37.0 Pulmonary valve stenosis	0.501	0.498	0.000
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.501	0.498	0.000
I39.4 Multiple valve disorders in diseases classified elsewhere	0.501	0.498	0.000
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.501	0.498	0.000
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.501	0.498	0.000
I39.1 Aortic valve disorders in diseases classified elsewhere	0.501	0.498	0.000
I39.0 Mitral valve disorders in diseases classified elsewhere	0.501	0.498	0.000
I40.9 Acute myocarditis, unspecified	0.501	0.498	0.000
I40.8 Other acute myocarditis	0.501	0.498	0.000
I40.1 Isolated myocarditis	0.501	0.498	0.000
I40.0 Infective myocarditis	0.501	0.498	0.000
I41.8 Myocarditis in other diseases classified elsewhere	0.501	0.498	0.000
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.501	0.498	0.000
I41.1 Myocarditis in viral diseases classified elsewhere	0.501	0.498	0.000
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.501	0.498	0.000
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.501	0.498	0.000
I43.2 Cardiomyopathy in nutritional diseases	0.501	0.498	0.000
I43.1 Cardiomyopathy in metabolic diseases	0.501	0.498	0.000
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere	0.501	0.498	0.000
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.501	0.498	0.000
I48.4 Atypical atrial flutter	0.501	0.498	0.000
I48.3 Typical atrial flutter	0.501	0.498	0.000
I48.2 Chronic atrial fibrillation	0.501	0.498	0.000
I48.1 Persistent atrial fibrillation	0.501	0.498	0.000
I48.0 Paroxysmal atrial fibrillation	0.501	0.498	0.000
I52.8 Other heart disorders in other diseases classified elsewhere	0.501	0.498	0.000
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere	0.501	0.498	0.000
I52.0 Other heart disorders in bacterial diseases classified elsewhere	0.501	0.498	0.000
N17.9 Acute renal failure, unspecified	0.502	0.498	0.000
F60 Specific personality disorders	0.501	0.499	0.000
I77 Other disorders of arteries and arterioles	0.501	0.499	0.000
Z11 Special screening examination for infectious and parasitic diseases	0.500	0.500	0.000
F10.9 Unspecified mental and behavioural disorder	0.499	0.500	0.000
F10.8 Other mental and behavioural disorders	0.499	0.500	0.000
F10.7 Residual and late-onset psychotic disorder	0.499	0.500	0.000
F10.6 Amnesic syndrome	0.499	0.500	0.000
F10.5 Psychotic disorder	0.499	0.500	0.000
I46.1 Sudden cardiac death, so described	0.496	0.504	0.000
M70-M79 Other soft tissue disorders	0.496	0.504	0.000
N70 Salpingitis and oophoritis	0.496	0.504	0.000
N60.0 Solitary cyst of breast	0.495	0.505	0.000
Y52 Agents primarily affecting the cardiovascular system	0.495	0.505	0.000
T14 Injury of unspecified body region	0.494	0.506	0.000
S81.9 Open wound of lower leg, part unspecified	0.493	0.507	0.000
S81.7 Multiple open wounds of lower leg	0.493	0.507	0.000
S82.5 Fracture of medial malleolus	0.493	0.507	0.000
S64 Injury of nerves at wrist and hand level	0.492	0.508	0.000
N41 Inflammatory diseases of prostate	0.491	0.509	0.000
V10-V19 Pedal cyclist injured in transport accident	0.490	0.509	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations