TreeWAS – Variant ID: rs2071288

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
# Top node	0.985	0.015	0.000
Chapter IX Diseases of the circulatory system	0.985	0.015	0.000
I20-I25 Ischaemic heart diseases	0.981	0.019	0.000
I25 Chronic ischaemic heart disease	0.969	0.031	0.000
I30-I52 Other forms of heart disease	0.952	0.048	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.944	0.056	0.000
I20 Angina pectoris	0.938	0.062	0.000
Chapter V Mental and behavioural disorders	0.923	0.077	0.000
Chapter II Neoplasms	0.922	0.078	0.000
Chapter X Diseases of the respiratory system	0.913	0.087	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.902	0.098	0.000
Chapter XXI Factors influencing health status and contact with health services	0.889	0.111	0.000
M20-M25 Other joint disorders	0.877	0.123	0.000
Z40-Z54 Persons encountering health services for specific procedures and health care	0.871	0.129	0.000
I20.0 Unstable angina	0.869	0.131	0.000
I25.2 Old myocardial infarction	0.850	0.150	0.000
I35 Nonrheumatic aortic valve disorders	0.846	0.154	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.839	0.161	0.000
Z51 Other medical care	0.831	0.169	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.823	0.177	0.000
Chapter VII Diseases of the eye and adnexa	0.819	0.181	0.000
C50-C50 Malignant neoplasm of breast	0.819	0.181	0.000
C15-C26 Malignant neoplasms of digestive organs	0.812	0.188	0.000
I25.1 Atherosclerotic heart disease	0.811	0.189	0.000
M25 Other joint disorders, not elsewhere classified	0.809	0.191	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.804	0.196	0.000
Chapter XIV Diseases of the genitourinary system	0.794	0.206	0.000
I20.9 Angina pectoris, unspecified	0.794	0.206	0.000
Z51.1 Chemotherapy session for neoplasm	0.794	0.206	0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.793	0.207	0.000
I49 Other cardiac arrhythmias	0.792	0.208	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.792	0.208	0.000
J20-J22 Other acute lower respiratory infections	0.790	0.210	0.000
M05-M14 Inflammatory polyarthropathies	0.786	0.214	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.785	0.215	0.000
I50 Heart failure	0.785	0.215	0.000
J40-J47 Chronic lower respiratory diseases	0.770	0.230	0.000
J00-J06 Acute upper respiratory infections	0.769	0.231	0.000
E70-E90 Metabolic disorders	0.768	0.232	0.000
M15-M19 Arthrosis	0.768	0.232	0.000
M20 Acquired deformities of fingers and toes	0.763	0.237	0.000
I44 Atrioventricular and left bundle-branch block	0.761	0.239	0.000
Z45 Adjustment and management of implanted device	0.760	0.240	0.000
I35.0 Aortic (valve) stenosis	0.754	0.246	0.000
F30-F39 Mood [affective] disorders	0.753	0.247	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.748	0.252	0.000
Z51.4 Preparatory care for treatment, not elsewhere classified	0.747	0.253	0.000
C50 Malignant neoplasm of breast	0.744	0.256	0.000
J80-J84 Other respiratory diseases principally affecting the interstitium	0.737	0.263	0.000
M25.7 Osteophyte	0.732	0.268	0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.731	0.269	0.000
I05-I09 Chronic rheumatic heart diseases	0.730	0.270	0.000
M50-M54 Other dorsopathies	0.725	0.275	0.000
M86-M90 Other osteopathies	0.723	0.277	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.723	0.277	0.000
I42 Cardiomyopathy	0.722	0.278	0.000
I20.8 Other forms of angina pectoris	0.718	0.282	0.000
Z50 Care involving use of rehabilitation procedures	0.717	0.283	0.000
Chapter VIII Diseases of the ear and mastoid process	0.709	0.291	0.000
N17-N19 Renal failure	0.707	0.293	0.000
Chapter XXII Codes for special purposes	0.706	0.293	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.706	0.293	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.706	0.293	0.000
I00-I02 Acute rheumatic fever	0.706	0.294	0.000
J09-J18 Influenza and pneumonia	0.706	0.294	0.000
I24 Other acute ischaemic heart diseases	0.704	0.296	0.000
I23 Certain current complications following acute myocardial infarction	0.704	0.296	0.000
I22 Subsequent myocardial infarction	0.704	0.296	0.000
J22 Unspecified acute lower respiratory infection	0.703	0.297	0.000
I45 Other conduction disorders	0.697	0.302	0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.697	0.303	0.000
I47 Paroxysmal tachycardia	0.696	0.304	0.000
I25.6 Silent myocardial ischaemia	0.695	0.305	0.000
I25.5 Ischaemic cardiomyopathy	0.695	0.305	0.000
I25.4 Coronary artery aneurysm	0.695	0.305	0.000
I25.3 Aneurysm of heart	0.695	0.305	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.695	0.305	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.694	0.306	0.000
F17 Mental and behavioural disorders due to use of tobacco	0.693	0.307	0.000
C18 Malignant neoplasm of colon	0.693	0.307	0.000
N60-N64 Disorders of breast	0.692	0.308	0.000
C60-C63 Malignant neoplasms of male genital organs	0.689	0.311	0.000
J44 Other chronic obstructive pulmonary disease	0.689	0.311	0.000
F41 Other anxiety disorders	0.686	0.314	0.000
I34 Nonrheumatic mitral valve disorders	0.686	0.314	0.000
I52 Other heart disorders in diseases classified elsewhere	0.683	0.317	0.000
I48 Atrial fibrillation and flutter	0.683	0.317	0.000
I46 Cardiac arrest	0.683	0.317	0.000
I43 Cardiomyopathy in diseases classified elsewhere	0.683	0.317	0.000
I41 Myocarditis in diseases classified elsewhere	0.683	0.317	0.000
I40 Acute myocarditis	0.683	0.317	0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.683	0.317	0.000
I37 Pulmonary valve disorders	0.683	0.317	0.000
I36 Nonrheumatic tricuspid valve disorders	0.683	0.317	0.000
I33 Acute and subacute endocarditis	0.683	0.317	0.000
I32 Pericarditis in diseases classified elsewhere	0.683	0.317	0.000
I31 Other diseases of pericardium	0.683	0.317	0.000
I30 Acute pericarditis	0.683	0.317	0.000
I38 Endocarditis, valve unspecified	0.683	0.317	0.000
Chapter VI Diseases of the nervous system	0.682	0.318	0.000
Z40 Prophylactic surgery	0.681	0.319	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.679	0.321	0.000
I49.5 Sick sinus syndrome	0.678	0.322	0.000
M25.77 Osteophyte (Ankle and foot)	0.677	0.323	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.677	0.323	0.000
M91-M94 Chondropathies	0.677	0.323	0.000
M60-M63 Disorders of muscles	0.677	0.323	0.000
M40-M43 Deforming dorsopathies	0.677	0.323	0.000
M00-M03 Infectious arthropathies	0.677	0.323	0.000
M65-M68 Disorders of synovium and tendon	0.673	0.326	0.000
I20.1 Angina pectoris with documented spasm	0.672	0.327	0.000
Chapter XX External causes of morbidity and mortality	0.671	0.329	0.000
M13 Other arthritis	0.669	0.331	0.000
C51-C58 Malignant neoplasms of female genital organs	0.669	0.331	0.000
Z45.2 Adjustment and management of vascular access device	0.669	0.331	0.000
D00-D09 In situ neoplasms	0.667	0.333	0.000
N70-N77 Inflammatory diseases of female pelvic organs	0.666	0.334	0.000
I73 Other peripheral vascular diseases	0.666	0.334	0.000
M25.5 Pain in joint	0.666	0.334	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.663	0.337	0.000
F99-F99 Unspecified mental disorder	0.662	0.338	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.662	0.338	0.000
F80-F89 Disorders of psychological development	0.662	0.338	0.000
F70-F79 Mental retardation	0.662	0.338	0.000
F60-F69 Disorders of adult personality and behaviour	0.662	0.338	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.662	0.338	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.662	0.338	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.662	0.338	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.661	0.339	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.661	0.339	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.661	0.339	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.661	0.339	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.661	0.339	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.661	0.339	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.661	0.339	0.000
E86 Volume depletion	0.659	0.341	0.000
I51 Complications and ill-defined descriptions of heart disease	0.655	0.345	0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.654	0.346	0.000
J60-J70 Lung diseases due to external agents	0.654	0.346	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.654	0.346	0.000
I60-I69 Cerebrovascular diseases	0.652	0.348	0.000
C64-C68 Malignant neoplasms of urinary tract	0.652	0.348	0.000
Chapter I Certain infectious and parasitic diseases	0.651	0.348	0.000
M20.2 Hallux rigidus	0.651	0.348	0.000
M19 Other arthrosis	0.650	0.350	0.000
M20.1 Hallux valgus (acquired)	0.649	0.351	0.000
I35.1 Aortic (valve) insufficiency	0.649	0.351	0.000
J06 Acute upper respiratory infections of multiple and unspecified sites	0.649	0.351	0.000
E00-E07 Disorders of thyroid gland	0.649	0.351	0.000
M80-M85 Disorders of bone density and structure	0.648	0.352	0.000
Z51.2 Other chemotherapy	0.646	0.354	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.644	0.356	0.000
C19 Malignant neoplasm of rectosigmoid junction	0.642	0.358	0.000
Z47 Other orthopaedic follow-up care	0.641	0.359	0.000
J47 Bronchiectasis	0.641	0.359	0.000
J95-J99 Other diseases of the respiratory system	0.640	0.360	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.639	0.361	0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.638	0.362	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.633	0.367	0.000
M18 Arthrosis of first carpometacarpal joint	0.631	0.369	0.000
F32 Depressive episode	0.631	0.369	0.000
I50.1 Left ventricular failure	0.631	0.369	0.000
I21 Acute myocardial infarction	0.629	0.370	0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.629	0.371	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.629	0.371	0.000
M35 Other systemic involvement of connective tissue	0.629	0.371	0.000
M34 Systemic sclerosis	0.629	0.371	0.000
M33 Dermatopolymyositis	0.629	0.371	0.000
M32 Systemic lupus erythematosus	0.629	0.371	0.000
M31 Other necrotising vasculopathies	0.629	0.371	0.000
M30 Polyarteritis nodosa and related conditions	0.629	0.371	0.000
M24 Other specific joint derangements	0.629	0.371	0.000
M22 Disorders of patella	0.629	0.371	0.000
M21 Other acquired deformities of limbs	0.629	0.371	0.000
M45-M49 Spondylopathies	0.627	0.372	0.000
Z54 Convalescence	0.624	0.375	0.000
Z52 Donors of organs and tissues	0.624	0.375	0.000
Z49 Care involving dialysis	0.624	0.375	0.000
Z48 Other surgical follow-up care	0.624	0.375	0.000
Z44 Fitting and adjustment of external prosthetic device	0.624	0.375	0.000
Z43 Attention to artificial openings	0.624	0.375	0.000
Z41 Procedures for purposes other than remedying health state	0.624	0.375	0.000
H53-H54 Visual disturbances and blindness	0.624	0.376	0.000
C50.4 Upper-outer quadrant of breast	0.623	0.377	0.000
S50-S59 Injuries to the elbow and forearm	0.622	0.378	0.000
F17.1 Harmful use	0.622	0.378	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.621	0.379	0.001
L60-L75 Disorders of skin appendages	0.621	0.379	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.620	0.379	0.000
J44.9 Chronic obstructive pulmonary disease, unspecified	0.620	0.380	0.000
N63 Unspecified lump in breast	0.620	0.380	0.000
Z46 Fitting and adjustment of other devices	0.618	0.382	0.000
C50.2 Upper-inner quadrant of breast	0.617	0.383	0.000
M10 Gout	0.613	0.387	0.000
I44.7 Left bundle-branch block, unspecified	0.611	0.389	0.000
J81 Pulmonary oedema	0.610	0.389	0.000
Z00-Z13 Persons encountering health services for examination and investigation	0.610	0.390	0.000
E83 Disorders of mineral metabolism	0.609	0.391	0.000
Z70-Z76 Persons encountering health services in other circumstances	0.607	0.393	0.000
I35.9 Aortic valve disorder, unspecified	0.607	0.393	0.000
I35.8 Other aortic valve disorders	0.607	0.393	0.000
I35.2 Aortic (valve) stenosis with insufficiency	0.607	0.393	0.000
C20 Malignant neoplasm of rectum	0.605	0.395	0.000
S40-S49 Injuries to the shoulder and upper arm	0.602	0.398	0.000
E50-E64 Other nutritional deficiencies	0.602	0.398	0.000
E40-E46 Malnutrition	0.602	0.398	0.000
E20-E35 Disorders of other endocrine glands	0.602	0.398	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.602	0.398	0.000
M70-M79 Other soft tissue disorders	0.601	0.399	0.000
M54 Dorsalgia	0.599	0.401	0.000
S80-S89 Injuries to the knee and lower leg	0.596	0.404	0.000
Z51.9 Medical care, unspecified	0.596	0.404	0.000
Z51.8 Other specified medical care	0.596	0.404	0.000
Z51.6 Desensitisation to allergens	0.596	0.404	0.000
Z51.3 Blood transfusion without reported diagnosis	0.596	0.404	0.000
I50.0 Congestive heart failure	0.593	0.407	0.000
C50.9 Breast, unspecified	0.592	0.408	0.000
E65-E68 Obesity and other hyperalimentation	0.591	0.409	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	0.591	0.409	0.000
N10-N16 Renal tubulo-interstitial diseases	0.590	0.410	0.000
I71 Aortic aneurysm and dissection	0.589	0.410	0.000
N17 Acute renal failure	0.589	0.411	0.000
H55-H59 Other disorders of eye and adnexa	0.587	0.412	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.587	0.412	0.000
H43-H45 Disorders of vitreous body and globe	0.587	0.412	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.587	0.412	0.000
H10-H13 Disorders of conjunctiva	0.587	0.412	0.000
M13.9 Arthritis, unspecified	0.586	0.414	0.000
I50.9 Heart failure, unspecified	0.584	0.416	0.000
J02 Acute pharyngitis	0.584	0.416	0.000
F10 Mental and behavioural disorders due to use of alcohol	0.583	0.417	0.000
Z53 Persons encountering health services for specifie procedures, not carried out	0.583	0.417	0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.582	0.417	0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.582	0.418	0.000
C26 Malignant neoplasm of other and ill-defined digestive organs	0.582	0.418	0.000
C25 Malignant neoplasm of pancreas	0.582	0.418	0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.582	0.418	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.582	0.418	0.000
C21 Malignant neoplasm of anus and anal canal	0.582	0.418	0.000
C17 Malignant neoplasm of small intestine	0.582	0.418	0.000
C16 Malignant neoplasm of stomach	0.582	0.418	0.000
C15 Malignant neoplasm of oesophagus	0.582	0.418	0.000
C23 Malignant neoplasm of gallbladder	0.582	0.418	0.000
H02 Other disorders of eyelid	0.581	0.419	0.000
M25.9 Joint disorder, unspecified	0.580	0.420	0.000
M25.8 Other specified joint disorders	0.580	0.420	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.580	0.420	0.000
M25.4 Effusion of joint	0.580	0.420	0.000
M25.3 Other instability of joint	0.580	0.420	0.000
M25.2 Flail joint	0.580	0.420	0.000
M25.1 Fistula of joint	0.580	0.420	0.000
M25.0 Haemarthrosis	0.580	0.420	0.000
C18.9 Colon, unspecified	0.578	0.422	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.576	0.424	0.000
I78 Diseases of capillaries	0.576	0.424	0.000
I77 Other disorders of arteries and arterioles	0.576	0.424	0.000
I74 Arterial embolism and thrombosis	0.576	0.424	0.000
I72 Other aneurysm	0.576	0.424	0.000
I70 Atherosclerosis	0.576	0.424	0.000
F41.9 Anxiety disorder, unspecified	0.576	0.424	0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified	0.576	0.424	0.000
J90-J94 Other diseases of pleura	0.575	0.425	0.000
Z45.0 Adjustment and management of cardiac pacemaker	0.573	0.427	0.000
N99-N99 Other disorders of the genitourinary system	0.569	0.431	0.000
N00-N08 Glomerular diseases	0.569	0.431	0.000
S00-S09 Injuries to the head	0.569	0.431	0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.568	0.431	0.000
F18 Mental and behavioural disorders due to use of volatile solvents	0.568	0.431	0.000
F16 Mental and behavioural disorders due to use of hallucinogens	0.568	0.431	0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.568	0.431	0.000
F14 Mental and behavioural disorders due to use of cocaine	0.568	0.431	0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.568	0.431	0.000
F12 Mental and behavioural disorders due to use of cannabinoids	0.568	0.431	0.000
F11 Mental and behavioural disorders due to use of opioids	0.568	0.431	0.000
I49.9 Cardiac arrhythmia, unspecified	0.568	0.432	0.000
I49.8 Other specified cardiac arrhythmias	0.568	0.432	0.000
I49.4 Other and unspecified premature depolarisation	0.568	0.432	0.000
I49.3 Ventricular premature depolarisation	0.568	0.432	0.000
I49.2 Junctional premature depolarisation	0.568	0.432	0.000
I49.1 Atrial premature depolarisation	0.568	0.432	0.000
I49.0 Ventricular fibrillation and flutter	0.568	0.432	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.568	0.432	0.000
T79-T79 Certain early complications of trauma	0.568	0.432	0.000
T66-T78 Other and unspecified effects of external causes	0.568	0.432	0.000
T33-T35 Frostbite	0.568	0.432	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.568	0.432	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.568	0.432	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.568	0.432	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.568	0.432	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.568	0.432	0.000
T00-T07 Injuries involving multiple body regions	0.568	0.432	0.000
S90-S99 Injuries to the ankle and foot	0.568	0.432	0.000
S70-S79 Injuries to the hip and thigh	0.568	0.432	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.568	0.432	0.000
S20-S29 Injuries to the thorax	0.568	0.432	0.000
S10-S19 Injuries to the neck	0.568	0.432	0.000
N18 Chronic renal failure	0.568	0.432	0.000
I73.9 Peripheral vascular disease, unspecified	0.567	0.433	0.000
J21 Acute bronchiolitis	0.567	0.433	0.000
J20 Acute bronchitis	0.567	0.433	0.000
M19.9 Arthrosis, unspecified	0.566	0.434	0.000
M89 Other disorders of bone	0.565	0.434	0.000
I44.0 Atrioventricular block, first degree	0.565	0.435	0.000
E78.0 Pure hypercholesterolaemia	0.564	0.436	0.000
M14 Arthropathies in other diseases classified elsewhere	0.563	0.437	0.000
M12 Other specific arthropathies	0.563	0.437	0.000
M11 Other crystal arthropathies	0.563	0.437	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.563	0.437	0.000
M08 Juvenile arthritis	0.563	0.437	0.000
M07 Psoriatic and enteropathic arthropathies	0.563	0.437	0.000
M05 Seropositive rheumatoid arthritis	0.563	0.437	0.000
F48 Other neurotic disorders	0.563	0.437	0.000
F45 Somatoform disorders	0.563	0.437	0.000
F44 Dissociative [conversion] disorders	0.563	0.437	0.000
F43 Reaction to severe stress, and adjustment disorders	0.563	0.437	0.000
F42 Obsessive-compulsive disorder	0.563	0.437	0.000
F40 Phobic anxiety disorders	0.563	0.437	0.000
J06.9 Acute upper respiratory infection, unspecified	0.562	0.438	0.000
M16 Coxarthrosis [arthrosis of hip]	0.562	0.438	0.000
F41.2 Mixed anxiety and depressive disorder	0.562	0.438	0.000
H30-H36 Disorders of choroid and retina	0.560	0.440	0.000
Z50.1 Other physical therapy	0.559	0.440	0.000
J18 Pneumonia, organism unspecified	0.558	0.442	0.000
I42.0 Dilated cardiomyopathy	0.558	0.442	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.557	0.443	0.000
H65-H75 Diseases of middle ear and mastoid	0.557	0.443	0.000
N19 Unspecified renal failure	0.553	0.447	0.000
H25-H28 Disorders of lens	0.552	0.448	0.000
J41 Simple and mucopurulent chronic bronchitis	0.552	0.448	0.000
J46 Status asthmaticus	0.552	0.448	0.000
J42 Unspecified chronic bronchitis	0.552	0.448	0.000
J40 Bronchitis, not specified as acute or chronic	0.552	0.448	0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis	0.552	0.448	0.000
J04 Acute laryngitis and tracheitis	0.552	0.448	0.000
J03 Acute tonsillitis	0.552	0.448	0.000
J01 Acute sinusitis	0.552	0.448	0.000
J00 Acute nasopharyngitis [common cold]	0.552	0.448	0.000
E88 Other metabolic disorders	0.551	0.449	0.000
E85 Amyloidosis	0.551	0.449	0.000
E84 Cystic fibrosis	0.551	0.449	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.551	0.449	0.000
E79 Disorders of purine and pyrimidine metabolism	0.551	0.449	0.000
E77 Disorders of glycoprotein metabolism	0.551	0.449	0.000
E76 Disorders of glycosaminoglycan metabolism	0.551	0.449	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.551	0.449	0.000
E74 Other disorders of carbohydrate metabolism	0.551	0.449	0.000
E73 Lactose intolerance	0.551	0.449	0.000
E72 Other disorders of amino-acid metabolism	0.551	0.449	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.551	0.449	0.000
E70 Disorders of aromatic amino-acid metabolism	0.551	0.449	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.551	0.449	0.000
M15 Polyarthrosis	0.551	0.449	0.000
N25-N29 Other disorders of kidney and ureter	0.550	0.450	0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.549	0.451	0.000
C18.7 Sigmoid colon	0.548	0.452	0.000
I08 Multiple valve diseases	0.548	0.452	0.000
M20.6 Acquired deformity of toe(s), unspecified	0.547	0.453	0.000
M20.3 Other deformity of hallux (acquired)	0.547	0.453	0.000
M20.0 Deformity of finger(s)	0.547	0.453	0.000
H04 Disorders of lachrymal system	0.547	0.453	0.000
Z45.8 Adjustment and management of other implanted devices	0.546	0.454	0.000
I44.6 Other and unspecified fascicular block	0.546	0.454	0.000
I44.5 Left posterior fascicular block	0.546	0.454	0.000
I44.4 Left anterior fascicular block	0.546	0.454	0.000
I44.3 Other and unspecified atrioventricular block	0.546	0.454	0.000
I44.2 Atrioventricular block, complete	0.546	0.454	0.000
I44.1 Atrioventricular block, second degree	0.546	0.454	0.000
H40-H42 Glaucoma	0.545	0.455	0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms	0.545	0.455	0.000
Z45.9 Adjustment and management of unspecified implanted device	0.545	0.455	0.000
Z45.3 Adjustment and management of implanted hearing device	0.545	0.455	0.000
Z45.1 Adjustment and management of infusion pump	0.545	0.455	0.000
N72 Inflammatory disease of cervix uteri	0.545	0.455	0.000
F32.9 Depressive episode, unspecified	0.543	0.457	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.543	0.457	0.000
F38 Other mood [affective] disorders	0.540	0.460	0.000
F34 Persistent mood [affective] disorders	0.540	0.460	0.000
F33 Recurrent depressive disorder	0.540	0.460	0.000
F31 Bipolar affective disorder	0.540	0.460	0.000
F30 Manic episode	0.540	0.460	0.000
F39 Unspecified mood [affective] disorder	0.540	0.460	0.000
O00-O08 Pregnancy with abortive outcome	0.538	0.462	0.000
Z42 Follow-up care involving plastic surgery	0.537	0.463	0.000
L50-L54 Urticaria and erythema	0.537	0.463	0.000
L20-L30 Dermatitis and eczema	0.537	0.463	0.000
L10-L14 Bullous disorders	0.537	0.463	0.000
L00-L08 Infections of the skin and subcutaneous tissue	0.536	0.464	0.000
M25.55 Pain in joint (Pelvic region and thigh)	0.535	0.465	0.000
C50.8 Overlapping lesion of breast	0.534	0.466	0.000
C50.6 Axillary tail of breast	0.534	0.466	0.000
C50.5 Lower-outer quadrant of breast	0.534	0.466	0.000
C50.3 Lower-inner quadrant of breast	0.534	0.466	0.000
C50.1 Central portion of breast	0.534	0.466	0.000
C50.0 Nipple and areola	0.534	0.466	0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.533	0.467	0.000
J43 Emphysema	0.533	0.467	0.000
C77.2 Intra-abdominal lymph nodes	0.532	0.468	0.000
E87 Other disorders of fluid, electrolyte and acid-base balance	0.531	0.469	0.000
C34 Malignant neoplasm of bronchus and lung	0.530	0.470	0.000
L72 Follicular cysts of skin and subcutaneous tissue	0.530	0.470	0.000
M20.4 Other hammer toe(s) (acquired)	0.529	0.471	0.000
J84 Other interstitial pulmonary diseases	0.528	0.472	0.000
J82 Pulmonary eosinophilia, not elsewhere classified	0.528	0.472	0.000
J80 Adult respiratory distress syndrome	0.528	0.472	0.000
I10-I15 Hypertensive diseases	0.527	0.473	0.000
L80-L99 Other disorders of the skin and subcutaneous tissue	0.525	0.474	0.000
S60-S69 Injuries to the wrist and hand	0.525	0.474	0.000
M25.79 Osteophyte (Site unspecified)	0.525	0.475	0.000
M25.78 Osteophyte (Other)	0.525	0.475	0.000
M25.76 Osteophyte (Lower leg)	0.525	0.475	0.000
M25.75 Osteophyte (Pelvic region and thigh)	0.525	0.475	0.000
M25.74 Osteophyte (Hand)	0.525	0.475	0.000
M25.73 Osteophyte (Forearm)	0.525	0.475	0.000
M25.72 Osteophyte (Upper arm)	0.525	0.475	0.000
M25.71 Osteophyte (Shoulder region)	0.525	0.475	0.000
M25.70 Osteophyte (Multiple sites)	0.525	0.475	0.000
N73 Other female pelvic inflammatory diseases	0.524	0.476	0.000
C80 Malignant neoplasm without specification of site	0.524	0.476	0.000
C76 Malignant neoplasm of other and ill-defined sites	0.524	0.476	0.000
I09 Other rheumatic heart diseases	0.523	0.476	0.000
I07 Rheumatic tricuspid valve diseases	0.523	0.476	0.000
I06 Rheumatic aortic valve diseases	0.523	0.476	0.000
I05 Rheumatic mitral valve diseases	0.523	0.476	0.000
C61 Malignant neoplasm of prostate	0.522	0.478	0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.521	0.478	0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.520	0.479	0.000
M53 Other dorsopathies, not elsewhere classified	0.520	0.480	0.000
M50 Cervical disk disorders	0.520	0.480	0.000
M90 Osteopathies in diseases classified elsewhere	0.519	0.481	0.000
M88 Paget's disease of bone [osteitis deformans]	0.519	0.481	0.000
M87 Osteonecrosis	0.519	0.481	0.000
M86 Osteomyelitis	0.519	0.481	0.000
D10-D36 Benign neoplasms	0.519	0.481	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.518	0.481	0.000
O85-O92 Complications predominantly related to the puerperium	0.518	0.481	0.000
O80-O84 Delivery	0.518	0.481	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.518	0.481	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.518	0.481	0.000
H52 Disorders of refraction and accommodation	0.518	0.482	0.000
I42.9 Cardiomyopathy, unspecified	0.518	0.482	0.000
I42.8 Other cardiomyopathies	0.518	0.482	0.000
I42.7 Cardiomyopathy due to drugs and other external agents	0.518	0.482	0.000
I42.6 Alcoholic cardiomyopathy	0.518	0.482	0.000
I42.5 Other restrictive cardiomyopathy	0.518	0.482	0.000
I42.4 Endocardial fibroelastosis	0.518	0.482	0.000
I42.3 Endomyocardial (eosinophilic) disease	0.518	0.482	0.000
I42.2 Other hypertrophic cardiomyopathy	0.518	0.482	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.518	0.482	0.000
M25.56 Pain in joint (Lower leg)	0.517	0.482	0.000
N20-N23 Urolithiasis	0.516	0.484	0.000
I45.1 Other and unspecified right bundle-branch block	0.515	0.485	0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified	0.514	0.486	0.000
Z50.8 Care involving use of rehabilitation procedures	0.514	0.486	0.000
Z50.6 Orthoptic training	0.514	0.486	0.000
Z50.5 Speech therapy	0.514	0.486	0.000
Z50.4 Psychotherapy, not elsewhere classified	0.514	0.486	0.000
Z50.3 Drug rehabilitation	0.514	0.486	0.000
Z50.2 Alcohol rehabilitation	0.514	0.486	0.000
Z50.0 Cardiac rehabilitation	0.514	0.486	0.000
L40-L45 Papulosquamous disorders	0.513	0.487	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.512	0.487	0.000
I51.8 Other ill-defined heart diseases	0.512	0.488	0.000
I47.1 Supraventricular tachycardia	0.512	0.488	0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.511	0.489	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.510	0.489	0.000
H80-H83 Diseases of inner ear	0.508	0.492	0.000
H60-H62 Diseases of external ear	0.508	0.492	0.000
M13.90 Arthritis, unspecified (Multiple sites)	0.508	0.492	0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.508	0.492	0.000
M06 Other rheumatoid arthritis	0.507	0.492	0.000
P90-P96 Other disorders originating in the perinatal period	0.506	0.493	0.000
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn	0.506	0.493	0.000
P75-P78 Digestive system disorders of fetus and newborn	0.506	0.493	0.000
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn	0.506	0.493	0.000
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn	0.506	0.493	0.000
P35-P39 Infections specific to the perinatal period	0.506	0.493	0.000
P20-P29 Respiratory and cardiovascular disorders specific to the perinatal period	0.506	0.493	0.000
P10-P15 Birth trauma	0.506	0.493	0.000
P05-P08 Disorders related to length of gestation and fetal growth	0.506	0.493	0.000
P00-P04 Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery	0.506	0.493	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.506	0.493	0.000
Q80-Q89 Other congenital malformations	0.506	0.493	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.506	0.493	0.000
Q60-Q64 Congenital malformations of the urinary system	0.506	0.493	0.000
Q50-Q56 Congenital malformations of genital organs	0.506	0.493	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.506	0.493	0.000
Q35-Q37 Cleft lip and cleft palate	0.506	0.493	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.506	0.493	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.506	0.493	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.506	0.493	0.000
Q00-Q07 Congenital malformations of the nervous system	0.506	0.493	0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.506	0.493	0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.506	0.493	0.000
I02 Rheumatic chorea	0.506	0.494	0.000
I01 Rheumatic fever with heart involvement	0.506	0.494	0.000
I00 Rheumatic fever without mention of heart involvement	0.506	0.494	0.000
J17 Pneumonia in diseases classified elsewhere	0.506	0.494	0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified	0.506	0.494	0.000
J15 Bacterial pneumonia, not elsewhere classified	0.506	0.494	0.000
J12 Viral pneumonia, not elsewhere classified	0.506	0.494	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations