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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2236602
log Bayes Factor = 12.1767
Chromosome 1   position 156,627,069  (GRCh37) Explore rs2236602 on Ensembl!
Variant rs2236602 is part of Cluster X0117

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter II Neoplasms
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.999 0.001 0.000
Z51 Other medical care
0.999 0.001 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
Chapter XX External causes of morbidity and mortality
0.998 0.002 0.000
Chapter XXI Factors influencing health status and contact with health services
0.997 0.003 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.997 0.003 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.996 0.004 0.000
Z51.0 Radiotherapy session
0.994 0.006 0.000
C34 Malignant neoplasm of bronchus and lung
0.994 0.006 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.984 0.016 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.984 0.016 0.000
Chapter I Certain infectious and parasitic diseases
0.982 0.018 0.000
M20-M25 Other joint disorders
0.978 0.022 0.000
C15-C26 Malignant neoplasms of digestive organs
0.978 0.022 0.000
M65-M68 Disorders of synovium and tendon
0.972 0.028 0.000
M23 Internal derangement of knee
0.971 0.029 0.000
M23.3 Other meniscus derangements
0.963 0.037 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.960 0.040 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.960 0.040 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.956 0.044 0.000
C34.9 Bronchus or lung, unspecified
0.956 0.044 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.955 0.045 0.000
C80 Malignant neoplasm without specification of site
0.954 0.046 0.000
C34.1 Upper lobe, bronchus or lung
0.953 0.047 0.000
S40-S49 Injuries to the shoulder and upper arm
0.942 0.058 0.000
C79 Secondary malignant neoplasm of other sites
0.940 0.060 0.000
M80-M85 Disorders of bone density and structure
0.937 0.063 0.000
C50-C50 Malignant neoplasm of breast
0.935 0.065 0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.933 0.067 0.000
Z41 Procedures for purposes other than remedying health state
0.928 0.072 0.000
Y95 Nosocomial condition
0.924 0.076 0.000
Z51.2 Other chemotherapy
0.922 0.078 0.000
A30-A49 Other bacterial diseases
0.922 0.078 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.921 0.079 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.920 0.080 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.919 0.081 0.000
Chapter V Mental and behavioural disorders
0.917 0.083 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.916 0.084 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.914 0.086 0.000
M65 Synovitis and tenosynovitis
0.910 0.089 0.000
C20 Malignant neoplasm of rectum
0.909 0.091 0.000
Chapter VIII Diseases of the ear and mastoid process
0.908 0.092 0.000
M31 Other necrotising vasculopathies
0.907 0.093 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.906 0.094 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.905 0.095 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.904 0.096 0.000
S60-S69 Injuries to the wrist and hand
0.904 0.096 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.904 0.096 0.000
Z43 Attention to artificial openings
0.902 0.098 0.000
Z50 Care involving use of rehabilitation procedures
0.896 0.104 0.000
C18 Malignant neoplasm of colon
0.893 0.107 0.000
Y43 Primarily systemic agents
0.892 0.108 0.000
M23.8 Other internal derangements of knee
0.889 0.111 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.888 0.112 0.000
C50 Malignant neoplasm of breast
0.888 0.112 0.000
Z42 Follow-up care involving plastic surgery
0.888 0.112 0.000
M67 Other disorders of synovium and tendon
0.882 0.118 0.000
C50.4 Upper-outer quadrant of breast
0.882 0.118 0.000
S90-S99 Injuries to the ankle and foot
0.881 0.119 0.000
Z41.1 Other plastic surgery for unacceptable cosmetic appearance
0.878 0.122 0.000
D50-D53 Nutritional anaemias
0.874 0.126 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.869 0.131 0.000
C77.3 Axillary and upper limb lymph nodes
0.868 0.132 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.867 0.133 0.000
C80.0 Malignant neoplasm, primary site unknown, so stated
0.866 0.134 0.000
Z50.1 Other physical therapy
0.865 0.135 0.000
C73 Malignant neoplasm of thyroid gland
0.864 0.136 0.000
B25-B34 Other viral diseases
0.864 0.136 0.000
C34.3 Lower lobe, bronchus or lung
0.863 0.137 0.000
Z52 Donors of organs and tissues
0.862 0.138 0.000
T39.0 Salicylates
0.856 0.144 0.000
S42 Fracture of shoulder and upper arm
0.855 0.145 0.000
M91-M94 Chondropathies
0.854 0.146 0.000
C80.9 Malignant neoplasm, unspecified
0.853 0.147 0.000
Z51.5 Palliative care
0.852 0.148 0.000
F30-F39 Mood [affective] disorders
0.846 0.153 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.846 0.154 0.000
T42.4 Benzodiazepines
0.844 0.156 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.844 0.156 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.843 0.157 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.838 0.162 0.000
M81 Osteoporosis without pathological fracture
0.838 0.162 0.000
C18.0 Caecum
0.837 0.163 0.000
T79-T79 Certain early complications of trauma
0.835 0.165 0.000
H90-H95 Other disorders of ear
0.835 0.165 0.000
C45 Mesothelioma
0.834 0.166 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.831 0.169 0.000
C32 Malignant neoplasm of larynx
0.827 0.173 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.826 0.174 0.000
T39.1 4-Aminophenol derivatives
0.825 0.174 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.825 0.175 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.824 0.176 0.000
Z57 Occupational exposure to risk-factors
0.824 0.176 0.000
S42.2 Fracture of upper end of humerus
0.823 0.177 0.000
Z43.6 Attention to other artificial openings of urinary tract
0.822 0.178 0.000
D60-D64 Aplastic and other anaemias
0.821 0.179 0.000
S60 Superficial injury of wrist and hand
0.821 0.179 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.821 0.179 0.000
S70-S79 Injuries to the hip and thigh
0.819 0.181 0.000
Chapter VI Diseases of the nervous system
0.814 0.186 0.000
A49 Bacterial infection of unspecified site
0.814 0.186 0.000
C78.7 Secondary malignant neoplasm of liver
0.813 0.187 0.000
V40-V49 Car occupant injured in transport accident
0.813 0.187 0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)
0.812 0.188 0.000
Z51.1 Chemotherapy session for neoplasm
0.811 0.189 0.000
F32 Depressive episode
0.810 0.190 0.000
Z54 Convalescence
0.806 0.194 0.000
M67.8 Other specified disorders of synovium and tendon
0.804 0.196 0.000
Y43.3 Other antineoplastic drugs
0.802 0.198 0.000
S42.20 Fracture of upper end of humerus (closed)
0.800 0.200 0.000
Z42.1 Follow-up care involving plastic surgery of breast
0.798 0.202 0.000
W20-W49 Exposure to inanimate mechanical forces
0.796 0.204 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.795 0.205 0.000
B99-B99 Other infectious diseases
0.795 0.205 0.000
Z51.3 Blood transfusion without reported diagnosis
0.794 0.206 0.000
F32.9 Depressive episode, unspecified
0.792 0.208 0.000
T92 Sequelae of injuries of upper limb
0.791 0.209 0.000
A15-A19 Tuberculosis
0.791 0.209 0.000
C25 Malignant neoplasm of pancreas
0.791 0.209 0.000
D51 Vitamin B12 deficiency anaemia
0.789 0.211 0.000
M31.3 Wegener's granulomatosis
0.787 0.213 0.000
S62 Fracture at wrist and hand level
0.787 0.213 0.000
Y48 Anaesthetics and therapeutic gases
0.782 0.218 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.781 0.219 0.000
B34 Viral infection of unspecified site
0.780 0.220 0.000
T66-T78 Other and unspecified effects of external causes
0.779 0.221 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.778 0.222 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.778 0.222 0.000
C78.0 Secondary malignant neoplasm of lung
0.777 0.223 0.000
B65-B83 Helminthiases
0.775 0.225 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.775 0.225 0.000
Z50.5 Speech therapy
0.774 0.226 0.000
M85 Other disorders of bone density and structure
0.771 0.229 0.000
C77.2 Intra-abdominal lymph nodes
0.770 0.230 0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.769 0.231 0.000
Z46 Fitting and adjustment of other devices
0.769 0.231 0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.768 0.232 0.000
T90 Sequelae of injuries of head
0.768 0.232 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.766 0.234 0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)
0.765 0.235 0.000
B35-B49 Mycoses
0.765 0.235 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.764 0.236 0.000
S41 Open wound of shoulder and upper arm
0.764 0.236 0.000
Z52.4 Kidney donor
0.764 0.236 0.000
Z43.0 Attention to tracheostomy
0.763 0.237 0.000
C50.8 Overlapping lesion of breast
0.763 0.237 0.000
X20-X29 Contact with venomous animals and plants
0.762 0.237 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.762 0.238 0.000
M30 Polyarteritis nodosa and related conditions
0.762 0.238 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.761 0.239 0.000
M40-M43 Deforming dorsopathies
0.760 0.240 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.759 0.241 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.757 0.243 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.756 0.244 0.000
A41 Other septicaemia
0.755 0.245 0.000
Y57 Other and unspecified drugs and medicaments
0.754 0.246 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.753 0.247 0.000
C18.1 Appendix
0.751 0.249 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.750 0.250 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.749 0.251 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.749 0.251 0.000
Y45.0 Opioids and related analgesics
0.749 0.251 0.000
A46 Erysipelas
0.748 0.252 0.000
V80-V89 Other land transport accidents
0.748 0.252 0.000
M84 Disorders of continuity of bone
0.748 0.252 0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)
0.747 0.253 0.000
S40 Superficial injury of shoulder and upper arm
0.746 0.254 0.000
C45.0 Mesothelioma of pleura
0.746 0.254 0.000
Z57.2 Occupational exposure to dust
0.745 0.255 0.000
D50 Iron deficiency anaemia
0.744 0.256 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.744 0.256 0.000
C51-C58 Malignant neoplasms of female genital organs
0.743 0.257 0.000
Y52 Agents primarily affecting the cardiovascular system
0.743 0.257 0.000
Q50-Q56 Congenital malformations of genital organs
0.742 0.258 0.000
S99 Other and unspecified injuries of ankle and foot
0.741 0.259 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.740 0.260 0.000
D37.4 Colon
0.740 0.260 0.000
M50-M54 Other dorsopathies
0.739 0.261 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.738 0.262 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.737 0.263 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.736 0.264 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.734 0.266 0.000
C79.2 Secondary malignant neoplasm of skin
0.734 0.266 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.733 0.267 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.733 0.267 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.733 0.267 0.000
M94 Other disorders of cartilage
0.732 0.267 0.000
X60-X84 Intentional self-harm
0.732 0.268 0.000
S91 Open wound of ankle and foot
0.732 0.268 0.000
V20-V29 Motorcycle rider injured in transport accident
0.731 0.269 0.000
M86-M90 Other osteopathies
0.730 0.269 0.000
C34.2 Middle lobe, bronchus or lung
0.729 0.271 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.729 0.271 0.000
M66 Spontaneous rupture of synovium and tendon
0.729 0.271 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.728 0.272 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.728 0.272 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.726 0.274 0.000
B15-B19 Viral hepatitis
0.726 0.274 0.000
M23.9 Internal derangement of knee, unspecified
0.725 0.275 0.000
Z43.5 Attention to cyctostomy
0.724 0.276 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.724 0.276 0.000
Y40 Systemic antibiotics
0.722 0.278 0.000
S10-S19 Injuries to the neck
0.722 0.278 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.722 0.278 0.000
T42.1 Iminostilbenes
0.721 0.279 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.721 0.279 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.720 0.280 0.000
B34.9 Viral infection, unspecified
0.719 0.281 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.719 0.281 0.000
H91 Other hearing loss
0.719 0.281 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.718 0.282 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M81.4 Drug-induced osteoporosis
0.717 0.283 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.716 0.283 0.000
Z51.9 Medical care, unspecified
0.716 0.284 0.000
Z51.6 Desensitisation to allergens
0.716 0.284 0.000
Z44 Fitting and adjustment of external prosthetic device
0.716 0.284 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
Y35-Y36 Legal intervention and operations of war
0.716 0.284 0.000
Y10-Y34 Event of undetermined intent
0.716 0.284 0.000
Y00-Y09 Assault
0.716 0.284 0.000
X85-X99 Assault
0.716 0.284 0.000
X30-X39 Exposure to forces of nature
0.716 0.284 0.000
X10-X19 Contact with heat and hot substances
0.716 0.284 0.000
X00-X09 Exposure to smoke, fire and flames
0.716 0.284 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.716 0.284 0.000
W75-W84 Other accidental threats to breathing
0.716 0.284 0.000
W65-W74 Accidental drowning and submersion
0.716 0.284 0.000
V98-V99 Other and unspecified transport accidents
0.716 0.284 0.000
V95-V97 Air and space transport accidents
0.716 0.284 0.000
V90-V94 Water transport accidents
0.716 0.284 0.000
V70-V79 Bus occupant injured in transport accident
0.716 0.284 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.716 0.284 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.716 0.284 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.716 0.284 0.000
V01-V09 Pedestrian injured in transport accident
0.716 0.284 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.715 0.285 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.715 0.285 0.000
C31 Malignant neoplasm of accessory sinuses
0.715 0.285 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.715 0.285 0.000
C37 Malignant neoplasm of thymus
0.715 0.285 0.000
C33 Malignant neoplasm of trachea
0.715 0.285 0.000
H65-H75 Diseases of middle ear and mastoid
0.715 0.285 0.000
M60-M63 Disorders of muscles
0.714 0.286 0.000
W50-W64 Exposure to animate mechanical forces
0.714 0.286 0.000
Z42.2 Follow-up care involving plastic surgery of other parts of trunk
0.714 0.286 0.000
X50-X57 Overexertion, travel and privation
0.713 0.287 0.000
C34.8 Overlapping lesion of bronchus and lung
0.712 0.288 0.000
C18.5 Splenic flexure
0.711 0.289 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.710 0.289 0.000
T91 Sequelae of injuries of neck and trunk
0.710 0.290 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.710 0.290 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.710 0.290 0.000
M35 Other systemic involvement of connective tissue
0.708 0.292 0.000
S60.9 Superficial injury of wrist and hand, unspecified
0.708 0.292 0.000
M23.5 Chronic instability of knee
0.707 0.293 0.000
Y59 Other and unspecified vaccines and biological substances
0.706 0.294 0.000
Y58 Bacterial vaccines
0.706 0.294 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.706 0.294 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.706 0.294 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.706 0.294 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.706 0.294 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.706 0.294 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.705 0.295 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.705 0.295 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.705 0.295 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.705 0.295 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.705 0.295 0.000
T36 Poisoning by systemic antibiotics
0.705 0.295 0.000
C78.2 Secondary malignant neoplasm of pleura
0.705 0.295 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.704 0.296 0.000
B50-B64 Protozoal diseases
0.704 0.296 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.704 0.296 0.000
A75-A79 Rickettsioses
0.704 0.296 0.000
A70-A74 Other diseases caused by chlamydiae
0.704 0.296 0.000
A65-A69 Other spirochaetal diseases
0.704 0.296 0.000
A20-A28 Certain zoonotic bacterial diseases
0.704 0.296 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.704 0.296 0.000
D37.7 Other digestive organs
0.704 0.296 0.000
Y43.0 Antiallergic and antiemetic drugs
0.704 0.296 0.000
M65.3 Trigger finger
0.704 0.296 0.000
C18.2 Ascending colon
0.702 0.298 0.000
D70 Agranulocytosis
0.702 0.298 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.701 0.298 0.000
C34.0 Main bronchus
0.701 0.299 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.701 0.299 0.000
M33 Dermatopolymyositis
0.701 0.299 0.000
M32 Systemic lupus erythematosus
0.701 0.299 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.701 0.299 0.000
C32.0 Glottis
0.701 0.299 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.701 0.299 0.000
C17 Malignant neoplasm of small intestine
0.701 0.299 0.000
C23 Malignant neoplasm of gallbladder
0.701 0.299 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.700 0.299 0.000
C71 Malignant neoplasm of brain
0.700 0.300 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.700 0.300 0.000
M34 Systemic sclerosis
0.699 0.300 0.000
Z63 Other problems related to primary support group, including family circumstances
0.699 0.300 0.000
M81.9 Osteoporosis, unspecified
0.699 0.300 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.699 0.301 0.000
C16 Malignant neoplasm of stomach
0.698 0.302 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.697 0.303 0.000
D80-D89 Certain disorders involving the immune mechanism
0.697 0.303 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.697 0.303 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.696 0.304 0.000
M23.1 Discoid meniscus (congenital)
0.696 0.304 0.000
M23.0 Cystic meniscus
0.696 0.304 0.000
A49.1 Streptococcal infection, unspecified
0.696 0.304 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.696 0.304 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.696 0.304 0.000
T98 Sequelae of other and unspecified effects of external causes
0.695 0.305 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.694 0.306 0.000
D37.5 Rectum
0.694 0.306 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.694 0.306 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.694 0.306 0.000
S61 Open wound of wrist and hand
0.694 0.306 0.000
M31.6 Other giant cell arteritis
0.694 0.306 0.000
D61 Other aplastic anaemias
0.692 0.308 0.000
M23.37 Other meniscus derangements-Capsular lig
0.691 0.309 0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.691 0.309 0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.691 0.309 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.690 0.310 0.000
Z47 Other orthopaedic follow-up care
0.690 0.310 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.688 0.311 0.000
Y98 Lifestyle-related condition
0.688 0.311 0.000
Y97 Environmental-pollution-related condition
0.688 0.311 0.000
Y96 Work-related condition
0.688 0.311 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.688 0.312 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.688 0.312 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.688 0.312 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.688 0.312 0.000
Z57.5 Occupational exposure to toxic agents in other industries
0.687 0.313 0.000
Q00-Q07 Congenital malformations of the nervous system
0.687 0.313 0.000
M24 Other specific joint derangements
0.687 0.313 0.000
M00-M03 Infectious arthropathies
0.686 0.314 0.000
Z51.8 Other specified medical care
0.686 0.314 0.000
C21 Malignant neoplasm of anus and anal canal
0.686 0.314 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.685 0.314 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.685 0.314 0.000
T39.4 Antirheumatics, not elsewhere classified
0.685 0.314 0.000
T39.2 Pyrazolone derivatives
0.685 0.314 0.000
D55-D59 Haemolytic anaemias
0.684 0.315 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.683 0.317 0.000
T68 Hypothermia
0.683 0.317 0.000
C77.1 Intrathoracic lymph nodes
0.681 0.319 0.000
A40 Streptococcal septicaemia
0.681 0.319 0.000
H90 Conductive and sensorineural hearing loss
0.681 0.319 0.000
B35 Dermatophytosis
0.681 0.319 0.000
H60-H62 Diseases of external ear
0.681 0.319 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.681 0.319 0.000
V49 Car occupant injured in other and unspecified transport accidents
0.681 0.319 0.000
C50.0 Nipple and areola
0.680 0.320 0.000
Z58 Problems related to physical environment
0.679 0.320 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.679 0.321 0.000
M67.4 Ganglion
0.677 0.323 0.000
M82 Osteoporosis in diseases classified elsewhere
0.677 0.323 0.000
C45.9 Mesothelioma, unspecified
0.676 0.324 0.000
Z42.3 Follow-up care involving plastic surgery of upper extremity
0.676 0.324 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.675 0.325 0.000
S48 Traumatic amputation of shoulder and upper arm
0.675 0.325 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.675 0.325 0.000
S44 Injury of nerves at shoulder and upper arm level
0.675 0.325 0.000
S47 Crushing injury of shoulder and upper arm
0.675 0.325 0.000
C25.0 Head of pancreas
0.675 0.325 0.000
Q76 Congenital malformations of spine and bony thorax
0.675 0.325 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.675 0.325 0.000
M80 Osteoporosis with pathological fracture
0.675 0.325 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.674 0.326 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.674 0.326 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.673 0.327 0.000
M83 Adult osteomalacia
0.671 0.328 0.000
M21 Other acquired deformities of limbs
0.671 0.329 0.000
A80-A89 Viral infections of the central nervous system
0.670 0.330 0.000
C50.5 Lower-outer quadrant of breast
0.669 0.331 0.000
S70 Superficial injury of hip and thigh
0.669 0.331 0.000
M54 Dorsalgia
0.667 0.333 0.000
Z54.0 Convalescence following surgery
0.667 0.333 0.000
Z41.9 Procedures for purposes other than remedying health state, unspecified
0.666 0.334 0.000
Z41.8 Other procedures for purposes other than remedying health state
0.666 0.334 0.000
Z41.3 Ear piercing
0.666 0.334 0.000
Z41.2 Routine and ritual circumcision
0.666 0.334 0.000
Z41.0 Hair transplant
0.666 0.334 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.665 0.335 0.000
S69 Other and unspecified injuries of wrist and hand
0.662 0.338 0.000
S60.2 Contusion of other parts of wrist and hand
0.662 0.338 0.000
A48 Other bacterial diseases, not elsewhere classified
0.661 0.339 0.000
A44 Bartonellosis
0.661 0.339 0.000
A43 Nocardiosis
0.661 0.339 0.000
A42 Actinomycosis
0.661 0.339 0.000
A39 Meningococcal infection
0.661 0.339 0.000
A37 Whooping cough
0.661 0.339 0.000
A36 Diphtheria
0.661 0.339 0.000
A32 Listeriosis
0.661 0.339 0.000
A31 Infection due to other mycobacteria
0.661 0.339 0.000
A30 Leprosy [Hansen's disease]
0.661 0.339 0.000
A38 Scarlet fever
0.661 0.339 0.000
A35 Other tetanus
0.661 0.339 0.000
A34 Obstetrical tetanus
0.661 0.339 0.000
A33 Tetanus neonatorum
0.661 0.339 0.000
B99 Other and unspecified infectious diseases
0.661 0.339 0.000
C75 Malignant neoplasm of other endocrine glands and related structures
0.660 0.340 0.000
C74 Malignant neoplasm of adrenal gland
0.660 0.340 0.000
Y76 Obstetric and gynaecological devices associated with adverse incidents
0.660 0.340 0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.660 0.340 0.000
T92.1 Sequelae of fracture of arm
0.660 0.340 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.659 0.341 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.659 0.341 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.659 0.341 0.000
T42.3 Barbiturates
0.659 0.341 0.000
T42.2 Succinimides and oxazolidinediones
0.659 0.341 0.000
T42.0 Hydantoin derivatives
0.659 0.341 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.659 0.341 0.000
T95 Sequelae of burns, corrosions and frostbite
0.659 0.341 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.659 0.341 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.659 0.341 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.659 0.341 0.000
M85.8 Other specified disorders of bone density and structure
0.659 0.341 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.658 0.342 0.000
F70-F79 Mental retardation
0.658 0.342 0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.657 0.342 0.000
Y45.2 Propionic acid derivatives
0.657 0.343 0.000
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system
0.657 0.343 0.000
C46 Kaposi's sarcoma
0.657 0.343 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.655 0.344 0.000
Q35-Q37 Cleft lip and cleft palate
0.655 0.344 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.655 0.344 0.000
H93 Other disorders of ear, not elsewhere classified
0.654 0.345 0.000
A16 Respiratory tuberculosis, not confirmed bacteriologically or histologically
0.654 0.346 0.000
Q80-Q89 Other congenital malformations
0.653 0.347 0.000
D38.1 Trachea, bronchus and lung
0.653 0.347 0.000
Z43.4 Attention to other artificial openings of digestive tract
0.653 0.347 0.000
M65.8 Other synovitis and tenosynovitis
0.653 0.347 0.000
M65.2 Calcific tendinitis
0.653 0.347 0.000
M65.1 Other infective (teno)synovitis
0.653 0.347 0.000
M65.0 Abscess of tendon sheath
0.653 0.347 0.000
C77.5 Intrapelvic lymph nodes
0.653 0.347 0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.652 0.347 0.000
Y79 Orthopaedic devices associated with adverse incidents
0.652 0.348 0.000
F80-F89 Disorders of psychological development
0.652 0.348 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.651 0.349 0.000
M93 Other osteochondropathies
0.651 0.349 0.000
M31.9 Necrotising vasculopathy, unspecified
0.650 0.350 0.000
M31.8 Other specified necrotising vasculopathies
0.650 0.350 0.000
M31.7 Microscopic polyangiitis
0.650 0.350 0.000
M31.4 Aortic arch syndrome [Takayasu]
0.650 0.350 0.000
M31.2 Lethal midline granuloma
0.650 0.350 0.000
M31.1 Thrombotic microangiopathy
0.650 0.350 0.000
M31.0 Hypersensitivity angiitis
0.650 0.350 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.649 0.351 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.649 0.351 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.649 0.351 0.000
S65 Injury of blood vessels at wrist and hand level
0.648 0.352 0.000
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)
0.648 0.352 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.646 0.353 0.000
A41.9 Septicaemia, unspecified
0.647 0.353 0.000
Z43.9 Attention to unspecified artificial opening
0.646 0.354 0.000
Z43.8 Attention to other artificial openings
0.646 0.354 0.000
Z43.7 Attention to artificial vagina
0.646 0.354 0.000
T90.9 Sequelae of unspecified injury of head
0.646 0.354 0.000
W25 Contact with sharp glass
0.646 0.354 0.000
G70-G73 Diseases of myoneural junction and muscle
0.644 0.356 0.000
G90-G99 Other disorders of the nervous system
0.644 0.356 0.000
D72 Other disorders of white blood cells
0.644 0.356 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.643 0.357 0.000
Z50.6 Orthoptic training
0.643 0.357 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.643 0.357 0.000
Z50.3 Drug rehabilitation
0.643 0.357 0.000
Y43.4 Immunosuppressive agents
0.642 0.357 0.000
C77.0 Lymph nodes of head, face and neck
0.642 0.358 0.000
M25 Other joint disorders, not elsewhere classified
0.642 0.358 0.000
S60.8 Other superficial injuries of wrist and hand
0.642 0.358 0.000
S99.9 Unspecified injury of ankle and foot
0.641 0.359 0.000
Y43.1 Antineoplastic antimetabolites
0.641 0.359 0.000
C18.8 Overlapping lesion of colon
0.640 0.360 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.640 0.360 0.000
S90 Superficial injury of ankle and foot
0.640 0.360 0.000
Y43.9 Primarily systemic agent, unspecified
0.640 0.360 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.640 0.360 0.000
Y43.6 Enzymes, not elsewhere classified
0.640 0.360 0.000
Y43.5 Acidifying and alkalising agents
0.640 0.360 0.000
Y43.2 Antineoplastic natural products
0.640 0.360 0.000
D00-D09 In situ neoplasms
0.639 0.361 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.638 0.362 0.000
A49.9 Bacterial infection, unspecified
0.638 0.362 0.000
M23.87 Other internal derangements of knee (Capsular ligament)
0.637 0.363 0.000
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)
0.637 0.363 0.000
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)
0.637 0.363 0.000
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.637 0.363 0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)
0.637 0.363 0.000
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.637 0.363 0.000
M23.80 Other internal derangements of knee (Multiple sites)
0.637 0.363 0.000
Z49 Care involving dialysis
0.637 0.363 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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