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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2242656
log Bayes Factor = 103.123
Chromosome 6   position 31,614,102  (GRCh37) Explore rs2242656 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E14.9 Without complications
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.001 0.999
E78.0 Pure hypercholesterolaemia
0.000 0.001 0.999
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.001 0.999
L40.5 Arthropathic psoriasis
0.000 0.001 0.999
I10 Essential (primary) hypertension
0.000 0.001 0.999
J45.9 Asthma, unspecified
0.000 0.002 0.998
E10.4 With neurological complications
0.000 0.003 0.997
H36.0 Diabetic retinopathy
0.000 0.003 0.997
E70-E90 Metabolic disorders
0.000 0.005 0.995
M06 Other rheumatoid arthritis
0.000 0.005 0.995
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.007 0.993
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.008 0.992
E07 Other disorders of thyroid
0.000 0.008 0.992
E83.1 Disorders of iron metabolism
0.991 0.009 0.000
E16 Other disorders of pancreatic internal secretion
0.000 0.011 0.989
E11.3 With ophthalmic complications
0.000 0.012 0.988
I10-I15 Hypertensive diseases
0.000 0.013 0.987
E07.9 Disorder of thyroid, unspecified
0.000 0.013 0.987
E16.2 Hypoglycaemia, unspecified
0.000 0.017 0.983
G35-G37 Demyelinating diseases of the central nervous system
0.981 0.019 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.022 0.978
L40-L45 Papulosquamous disorders
0.000 0.023 0.977
G37 Other demyelinating diseases of central nervous system
0.976 0.024 0.000
M05-M14 Inflammatory polyarthropathies
0.000 0.030 0.970
G37.9 Demyelinating disease of central nervous system, unspecified
0.965 0.035 0.000
E14.3 With ophthalmic complications
0.000 0.035 0.965
H36 Retinal disorders in diseases classified elsewhere
0.000 0.042 0.958
L43 Lichen planus
0.000 0.053 0.947
M06.3 Rheumatoid nodule
0.000 0.057 0.943
E78.2 Mixed hyperlipidaemia
0.000 0.064 0.936
M07 Psoriatic and enteropathic arthropathies
0.000 0.066 0.934
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.067 0.933
H30-H36 Disorders of choroid and retina
0.000 0.070 0.930
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.080 0.920
I20-I25 Ischaemic heart diseases
0.000 0.084 0.916
E78.8 Other disorders of lipoprotein metabolism
0.000 0.088 0.912
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.091 0.909
I15 Secondary hypertension
0.000 0.091 0.909
Chapter IX Diseases of the circulatory system
0.000 0.092 0.908
L43.9 Lichen planus, unspecified
0.000 0.092 0.908
M07.3 Other psoriatic arthropathies
0.000 0.092 0.908
M70-M79 Other soft tissue disorders
0.000 0.095 0.905
I25 Chronic ischaemic heart disease
0.000 0.096 0.904
I22 Subsequent myocardial infarction
0.000 0.096 0.904
M75 Shoulder lesions
0.000 0.099 0.901
E10.2 With renal complications
0.000 0.100 0.899
E10.8 With unspecified complications
0.000 0.102 0.898
E11.1 With ketoacidosis
0.000 0.108 0.892
M05 Seropositive rheumatoid arthritis
0.000 0.111 0.889
G37.8 Other specified demyelinating diseases of central nervous system
0.889 0.111 0.000
I25.5 Ischaemic cardiomyopathy
0.000 0.117 0.883
# Top node
0.000 0.118 0.882
E10.5 With peripheral circulatory complications
0.000 0.120 0.880
E10.0 With coma
0.000 0.121 0.879
M45-M49 Spondylopathies
0.000 0.121 0.879
M45 Ankylosing spondylitis
0.000 0.122 0.878
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.125 0.875
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.128 0.872
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.130 0.870
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.134 0.866
H35 Other retinal disorders
0.000 0.135 0.865
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.135 0.864
Chapter VII Diseases of the eye and adnexa
0.000 0.139 0.861
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.140 0.860
M06.34 Rheumatoid nodule (Hand)
0.000 0.140 0.860
M75.4 Impingement syndrome of shoulder
0.000 0.141 0.859
E10.6 With other specified complications
0.000 0.144 0.856
M75.0 Adhesive capsulitis of shoulder
0.000 0.145 0.855
I12 Hypertensive renal disease
0.000 0.149 0.851
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.159 0.841
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.162 0.838
M75.2 Bicipital tendinitis
0.000 0.164 0.836
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.165 0.835
M06.4 Inflammatory polyarthropathy
0.000 0.165 0.835
E11.5 With peripheral circulatory complications
0.000 0.166 0.834
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.169 0.831
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.172 0.828
E16.1 Other hypoglycaemia
0.000 0.175 0.825
I15.1 Hypertension secondary to other renal disorders
0.000 0.176 0.824
H35.8 Other specified retinal disorders
0.000 0.181 0.819
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.181 0.819
H34 Retinal vascular occlusions
0.000 0.182 0.818
I12.9 Hypertensive renal disease without renal failure
0.000 0.187 0.813
M75.3 Calcific tendinitis of shoulder
0.000 0.190 0.810
L43.8 Other lichen planus
0.000 0.197 0.803
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.201 0.799
E83 Disorders of mineral metabolism
0.745 0.201 0.054
E74 Other disorders of carbohydrate metabolism
0.000 0.205 0.795
E06 Thyroiditis
0.000 0.206 0.794
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.207 0.793
E78.4 Other hyperlipidaemia
0.000 0.214 0.786
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.216 0.784
E78.1 Pure hyperglyceridaemia
0.000 0.219 0.781
I11 Hypertensive heart disease
0.000 0.222 0.777
H43-H45 Disorders of vitreous body and globe
0.000 0.223 0.777
I25.1 Atherosclerotic heart disease
0.000 0.224 0.776
M79 Other soft tissue disorders, not elsewhere classified
0.000 0.225 0.775
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.226 0.774
L40.8 Other psoriasis
0.000 0.226 0.773
E11.2 With renal complications
0.000 0.227 0.773
I20 Angina pectoris
0.000 0.233 0.767
E05.9 Thyrotoxicosis, unspecified
0.000 0.238 0.762
M79.6 Pain in limb
0.000 0.241 0.759
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.243 0.756
H35.6 Retinal haemorrhage
0.000 0.245 0.755
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.248 0.752
H43 Disorders of vitreous body
0.000 0.249 0.751
M79.65 Pain in limb (Pelvic region and thigh)
0.000 0.254 0.746
E03.8 Other specified hypothyroidism
0.000 0.258 0.742
E14.1 With ketoacidosis
0.000 0.258 0.742
E11.0 With coma
0.000 0.259 0.741
L40.1 Generalised pustular psoriasis
0.000 0.259 0.741
E07.8 Other specified disorders of thyroid
0.000 0.263 0.737
I15.9 Seconday hypertension, unspecified
0.000 0.264 0.736
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.264 0.736
H30 Chorioretinal inflammation
0.000 0.264 0.736
E79 Disorders of purine and pyrimidine metabolism
0.000 0.265 0.735
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.267 0.733
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.268 0.732
M75.9 Shoulder lesion, unspecified
0.000 0.271 0.729
M70 Soft tissue disorders related to use, overuse and pressure
0.000 0.271 0.729
M65-M68 Disorders of synovium and tendon
0.000 0.271 0.729
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.729 0.271 0.000
H35.2 Other proliferative retinopathy
0.000 0.276 0.724
H34.8 Other retinal vascular occlusions
0.000 0.279 0.721
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E14.8 With unspecified complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.2 Withrenal complications
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
E78.6 Lipoprotein deficiency
0.000 0.284 0.716
E78.3 Hyperchylomicronaemia
0.000 0.284 0.716
E77 Disorders of glycoprotein metabolism
0.000 0.287 0.713
E76 Disorders of glycosaminoglycan metabolism
0.000 0.287 0.713
E72 Other disorders of amino-acid metabolism
0.000 0.287 0.713
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.287 0.713
E70 Disorders of aromatic amino-acid metabolism
0.000 0.287 0.713
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.287 0.713
H35.4 Peripheral retinal degeneration
0.000 0.287 0.713
M06.8 Other specified rheumatoid arthritis
0.000 0.287 0.713
M06.2 Rheumatoid bursitis
0.000 0.287 0.713
M06.1 Adult-onset Still's disease
0.000 0.287 0.713
E15 Nondiabetic hypoglycaemic coma
0.000 0.288 0.712
E07.1 Dyshormogenetic goitre
0.000 0.288 0.712
E07.0 Hypersecretion of calcitonin
0.000 0.288 0.712
E11.8 With unspecified complications
0.000 0.288 0.711
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.291 0.709
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.291 0.709
E16.4 Abnormal secretion of gastrin
0.000 0.291 0.709
E16.3 Increased secretion of glucagon
0.000 0.291 0.709
I13 Hypertensive heart and renal disease
0.000 0.292 0.708
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.293 0.707
E14.5 With peripheral circulatory complications
0.000 0.294 0.706
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.295 0.705
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.297 0.703
G36 Other acute disseminated demyelination
0.703 0.297 0.000
I25.3 Aneurysm of heart
0.000 0.297 0.703
I24 Other acute ischaemic heart diseases
0.000 0.298 0.702
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.299 0.701
L44 Other papulosquamous disorders
0.000 0.299 0.700
L41 Parapsoriasis
0.000 0.299 0.700
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.299 0.700
G37.5 Concentric sclerosis [Balo]
0.700 0.300 0.000
G37.4 Subacute necrotising myelitis
0.700 0.300 0.000
G37.2 Central pontine myelinolysis
0.700 0.300 0.000
G37.1 Central demyelination of corpus callosum
0.700 0.300 0.000
G37.0 Diffuse sclerosis
0.700 0.300 0.000
E40-E46 Malnutrition
0.000 0.300 0.700
I20.0 Unstable angina
0.000 0.302 0.698
M46 Other inflammatory spondylopathies
0.000 0.302 0.698
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.303 0.697
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.304 0.696
M08 Juvenile arthritis
0.000 0.304 0.696
H43.3 Other vitreous opacities
0.000 0.306 0.694
H43.8 Other disorders of vitreous body
0.000 0.310 0.690
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.311 0.689
M77 Other enthesopathies
0.000 0.312 0.688
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.313 0.687
E11.6 With other specified complications
0.000 0.314 0.686
E14.4 With neurological complications
0.000 0.318 0.682
E85 Amyloidosis
0.000 0.319 0.681
L42 Pityriasis rosea
0.000 0.320 0.680
L43.3 Subacute (active) lichen planus
0.000 0.321 0.679
L43.2 Lichenoid drug reaction
0.000 0.321 0.679
L43.1 Bullous lichen planus
0.000 0.321 0.679
L43.0 Hypertrophic lichen planus
0.000 0.321 0.679
M70.4 Prepatellar bursitis
0.000 0.323 0.677
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.323 0.676
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.324 0.676
M06.38 Rheumatoid nodule (Other)
0.000 0.324 0.676
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.324 0.676
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.324 0.676
M06.33 Rheumatoid nodule (Forearm)
0.000 0.324 0.676
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.324 0.676
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.324 0.676
H35.7 Separation of retinal layers
0.000 0.324 0.676
M07.6 Other enteropathic arthropathies
0.000 0.330 0.669
M07.5 Arthropathy in ulcerative colitis
0.000 0.330 0.669
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.330 0.669
M07.2 Psoriatic spondylitis
0.000 0.330 0.669
M07.1 Arthritis mutilans
0.000 0.330 0.669
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.330 0.669
E05.5 Thyroid crisis or storm
0.000 0.331 0.669
E05.4 Thyrotoxicosis factitia
0.000 0.331 0.669
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.331 0.669
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.333 0.667
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.336 0.664
E14.6 With other specified complications
0.000 0.336 0.664
M79.63 Pain in limb (Forearm)
0.000 0.336 0.663
M79.7 Fibromyalgia
0.000 0.338 0.662
E06.3 Autoimmune thyroiditis
0.000 0.338 0.662
E05.8 Other thyrotoxicosis
0.000 0.339 0.661
H46-H48 Disorders of optic nerve and visual pathways
0.000 0.339 0.660
E83.3 Disorders of phosphorus metabolism
0.643 0.340 0.017
M14 Arthropathies in other diseases classified elsewhere
0.000 0.341 0.659
E13 Other specified diabetes mellitus
0.000 0.347 0.653
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.347 0.653
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.347 0.652
I15.8 Other secondary hypertension
0.000 0.348 0.651
I15.2 Hypertension secondary to endocrine disorders
0.000 0.348 0.651
I15.0 Renovascular hypertension
0.000 0.348 0.651
I00-I02 Acute rheumatic fever
0.000 0.349 0.651
M07.38 Other psoriatic arthropathies (Other)
0.000 0.349 0.651
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.349 0.651
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.349 0.651
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.349 0.651
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.349 0.651
M73 Soft tissue disorders in diseases classified elsewhere
0.000 0.351 0.649
M65 Synovitis and tenosynovitis
0.000 0.351 0.649
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.351 0.649
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.352 0.648
I25.6 Silent myocardial ischaemia
0.000 0.352 0.648
M12 Other specific arthropathies
0.000 0.353 0.647
M75.8 Other shoulder lesions
0.000 0.354 0.646
E78.5 Hyperlipidaemia, unspecified
0.000 0.354 0.646
M70.46 Prepatellar bursitis-Lower Leg
0.000 0.360 0.640
M05.8 Other seropositive rheumatoid arthritis
0.000 0.362 0.637
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.362 0.637
M05.2 Rheumatoid vasculitis
0.000 0.362 0.637
M05.1 Rheumatoid lung disease
0.000 0.362 0.637
M05.0 Felty's syndrome
0.000 0.362 0.637
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.363 0.637
M79.62 Pain in limb (Upper arm)
0.000 0.364 0.636
I22.8 Subsequent myocardial infarction of other sites
0.000 0.365 0.635
I23 Certain current complications following acute myocardial infarction
0.000 0.365 0.635
H35.5 Hereditary retinal dystrophy
0.000 0.366 0.634
E83.5 Disorders of calcium metabolism
0.631 0.366 0.003
L40.3 Pustulosis palmaris et plantaris
0.000 0.367 0.633
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.368 0.632
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.371 0.629
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.371 0.629
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.371 0.629
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.371 0.629
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.371 0.629
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.371 0.629
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.371 0.629
L40.0 Psoriasis vulgaris
0.000 0.379 0.621
H35.1 Retinopathy of prematurity
0.000 0.379 0.620
M71 Other bursopathies
0.000 0.380 0.620
E03.1 Congenital hypothyroidism without goitre
0.000 0.382 0.618
I20.1 Angina pectoris with documented spasm
0.000 0.383 0.617
M65.4 Radial styloid tenosynovitis [de Quervain]
0.000 0.384 0.616
M91-M94 Chondropathies
0.000 0.389 0.611
H34.1 Central retinal artery occlusion
0.000 0.390 0.609
M79.69 Pain in limb (Site unspecified)
0.000 0.391 0.609
I25.4 Coronary artery aneurysm
0.000 0.391 0.609
M46.9 Inflammatory spondylopathy, unspecified
0.000 0.395 0.605
M49 Spondylopathies in diseases classified elsewhere
0.000 0.395 0.605
M77.1 Lateral epicondylitis
0.000 0.398 0.602
M11 Other crystal arthropathies
0.000 0.399 0.600
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.400 0.600
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.401 0.598
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.401 0.598
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.401 0.598
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.401 0.598
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.401 0.598
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.401 0.598
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.401 0.598
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.401 0.598
H34.9 Retinal vascular occlusion, unspecified
0.000 0.402 0.598
H30.9 Chorioretinal inflammation, unspecified
0.000 0.403 0.597
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.404 0.596
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.404 0.596
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.404 0.596
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.404 0.596
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.404 0.596
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.404 0.596
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.404 0.596
H34.2 Other retinal artery occlusions
0.000 0.409 0.591
I21 Acute myocardial infarction
0.000 0.413 0.587
H34.0 Transient retinal artery occlusion
0.000 0.414 0.586
E89.3 Postprocedural hypopituitarism
0.000 0.414 0.586
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.416 0.583
E84 Cystic fibrosis
0.000 0.416 0.583
H43.9 Disorder of vitreous body, unspecified
0.000 0.417 0.583
I20.9 Angina pectoris, unspecified
0.000 0.418 0.582
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.421 0.579
E88 Other metabolic disorders
0.000 0.423 0.577
H31 Other disorders of choroid
0.000 0.424 0.576
M79.79 Fibromyalgia (Site unspecified)
0.000 0.424 0.576
H47 Other disorders of optic [2nd] nerve and visual pathways
0.000 0.425 0.575
E83.9 Disorder of mineral metabolism, unspecified
0.534 0.427 0.039
E83.8 Other disorders of mineral metabolism
0.534 0.427 0.039
E83.2 Disorders of zinc metabolism
0.534 0.427 0.039
E83.0 Disorders of copper metabolism
0.534 0.427 0.039
M06.0 Seronegative rheumatoid arthritis
0.000 0.428 0.572
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.430 0.570
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.430 0.570
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.430 0.570
E74.2 Disorders of galactose metabolism
0.000 0.430 0.570
E74.1 Disorders of fructose metabolism
0.000 0.430 0.570
E74.0 Glycogen storage disease
0.000 0.430 0.570
M79.67 Pain in limb (Ankle and foot)
0.000 0.430 0.570
E06.5 Other chronic thyroiditis
0.000 0.431 0.569
E06.4 Drug-induced thyroiditis
0.000 0.431 0.569
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.431 0.569
E06.1 Subacute thyroiditis
0.000 0.431 0.569
E06.0 Acute thyroiditis
0.000 0.431 0.569
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.432 0.568
M79.60 Pain in limb (Multiple sites)
0.000 0.433 0.567
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.000 0.436 0.563
E73 Lactose intolerance
0.000 0.437 0.562
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.439 0.560
L10-L14 Bullous disorders
0.000 0.442 0.558
M46.4 Discitis, unspecified
0.000 0.442 0.558
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.000 0.443 0.557
H43.2 Crystalline deposits in vitreous body
0.000 0.443 0.557
M79.3 Panniculitis, unspecified
0.000 0.444 0.556
M77.5 Other enthesopathy of foot
0.000 0.447 0.553
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.451 0.548
M79.64 Pain in limb (Hand)
0.000 0.457 0.543
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.458 0.542
E06.9 Thyroiditis, unspecified
0.000 0.458 0.542
M77.12 Lateral epicondylitis (Upper arm)
0.000 0.459 0.541
M71.2 Synovial cyst of popliteal space [Baker]
0.000 0.461 0.539
H43.0 Vitreous prolapse
0.000 0.461 0.538
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.000 0.464 0.536
M79.5 Residual foreign body in soft tissue
0.000 0.466 0.534
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.467 0.533
M67 Other disorders of synovium and tendon
0.000 0.469 0.531
H30.8 Other chorioretinal inflammations
0.000 0.472 0.528
H30.2 Posterior cyclitis
0.000 0.472 0.528
H30.1 Disseminated chorioretinal inflammation
0.000 0.472 0.528
H30.0 Focal chorioretinal inflammation
0.000 0.472 0.528
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.473 0.527
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.473 0.527
E79.1 Lesch-Nyhan syndrome
0.000 0.473 0.527
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)
0.000 0.473 0.527
M70.7 Other bursitis of hip
0.000 0.474 0.525
K90 Intestinal malabsorption
0.000 0.476 0.524
M70.5 Other bursitis of knee
0.000 0.477 0.523
M70.9 Unspecified soft tissue disorder related to use, overuse and pressure
0.000 0.477 0.523
M70.8 Other soft tissue disorders related to use, overuse and pressure
0.000 0.477 0.523
M70.1 Bursitis of hand
0.000 0.477 0.523
M70.0 Chronic crepitant synovitis of hand and wrist
0.000 0.477 0.523
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.000 0.477 0.523
E65-E68 Obesity and other hyperalimentation
0.000 0.480 0.520
E89.0 Postprocedural hypothyroidism
0.000 0.482 0.518
E89.2 Postprocedural hypoparathyroidism
0.000 0.484 0.516
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.485 0.514
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.485 0.514
E89.5 Postprocedural testicular hypofunction
0.000 0.485 0.514
E89.1 Postprocedural hypoinsulinaemia
0.000 0.485 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.488 0.512
M79.2 Neuralgia and neuritis, unspecified
0.000 0.488 0.512
E85.9 Amyloidosis, unspecified
0.000 0.488 0.512
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.488 0.511
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.488 0.511
E70.3 Albinism
0.000 0.488 0.511
E70.2 Disorders of tyrosine metabolism
0.000 0.488 0.511
E70.1 Other hyperphenylalaninaemias
0.000 0.488 0.511
E70.0 Classical phenylketonuria
0.000 0.488 0.511
E71.3 Disorders of fatty-acid metabolism
0.000 0.488 0.511
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.488 0.511
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.488 0.511
E71.0 Maple-syrup-urine disease
0.000 0.488 0.511
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.488 0.511
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.488 0.511
E72.5 Disorders of glycine metabolism
0.000 0.488 0.511
E72.4 Disorders of ornithine metabolism
0.000 0.488 0.511
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.488 0.511
E72.2 Disorders of urea cycle metabolism
0.000 0.488 0.511
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.488 0.511
E72.0 Disorders of amino-acid transport
0.000 0.488 0.511
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.488 0.511
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.488 0.511
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.488 0.511
E76.2 Other mucopolysaccharidoses
0.000 0.488 0.511
E76.1 Mucopolysaccharidosis, type II
0.000 0.488 0.511
E76.0 Mucopolysaccharidosis, type I
0.000 0.488 0.511
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.488 0.511
E77.8 Other disorders of glycoprotein metabolism
0.000 0.488 0.511
E77.1 Defects in glycoprotein degradation
0.000 0.488 0.511
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.488 0.511
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.489 0.511
M06.18 Adult-onset Still's disease (Other)
0.000 0.489 0.511
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.489 0.511
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.489 0.511
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.489 0.511
M06.14 Adult-onset Still's disease (Hand)
0.000 0.489 0.511
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.489 0.511
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.489 0.511
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.489 0.511
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.489 0.511
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.489 0.511
M06.28 Rheumatoid bursitis (Other)
0.000 0.489 0.511
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.489 0.511
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.489 0.511
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.489 0.511
M06.24 Rheumatoid bursitis (Hand)
0.000 0.489 0.511
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.489 0.511
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.489 0.511
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.489 0.511
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.489 0.511
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.489 0.511
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.489 0.511
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.489 0.511
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.489 0.511
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.489 0.511
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.489 0.511
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.489 0.511
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.489 0.511
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.489 0.511
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.489 0.511
H47.2 Optic atrophy
0.000 0.490 0.510
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.001 0.491 0.509
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.492 0.508
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.492 0.508
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.492 0.508
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.492 0.508
I21.4 Acute subendocardial myocardial infarction
0.000 0.493 0.507
G36.9 Acute disseminated demyelination, unspecified
0.504 0.496 0.000
G36.8 Other specified acute disseminated demyelination
0.504 0.496 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.504 0.496 0.000
G36.0 Neuromyelitis optica [Devic]
0.504 0.496 0.000
M10 Gout
0.000 0.496 0.504
M72 Fibroblastic disorders
0.000 0.497 0.503
L41.9 Parapsoriasis, unspecified
0.000 0.498 0.502
L41.8 Other parapsoriasis
0.000 0.498 0.502
L41.5 Retiform parapsoriasis
0.000 0.498 0.502
L41.4 Large plaque parapsoriasis
0.000 0.498 0.502
L41.3 Small plaque parapsoriasis
0.000 0.498 0.502
L41.2 Lymphomatoid papulosis
0.000 0.498 0.502
L41.1 Pityriasis lichenoides chronica
0.000 0.498 0.502
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.498 0.502
L44.9 Papulosquamous disorder, unspecified
0.000 0.498 0.502
L44.8 Other specified papulosquamous disorders
0.000 0.498 0.502
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.498 0.502
L44.3 Lichen ruber moniliformis
0.000 0.498 0.502
L44.2 Lichen striatus
0.000 0.498 0.502
L44.1 Lichen nitidus
0.000 0.498 0.502
L44.0 Pityriasis rubra pilaris
0.000 0.498 0.502

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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