TreeWAS – Variant ID: rs2255280

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	No effect posterior probability	Protective posterior probability
Chapter XXI Factors influencing health status and contact with health services	0.088	0.912
# Top node	0.091	0.909
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.097	0.903
Chapter VII Diseases of the eye and adnexa	0.117	0.883
Z95 Presence of cardiac and vascular implants and grafts	0.127	0.873
Z86 Personal history of certain other diseases	0.129	0.871
Chapter IV Endocrine, nutritional and metabolic diseases	0.138	0.862
Z00-Z13 Persons encountering health services for examination and investigation	0.139	0.861
H30-H36 Disorders of choroid and retina	0.143	0.857
Chapter XX External causes of morbidity and mortality	0.161	0.839
Z88 Personal history of allergy to drugs, medicaments and biologocal substances	0.169	0.831
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms	0.172	0.828
Z95.5 Presence of coronary angioplasty implant and graft	0.173	0.827
Chapter V Mental and behavioural disorders	0.188	0.812
E10-E14 Diabetes mellitus	0.198	0.802
Z70-Z76 Persons encountering health services in other circumstances	0.198	0.802
Z85 Personal history of malignant neoplasm	0.209	0.791
Z86.7 Personal history of diseases of the circulatory system	0.213	0.787
Z88.0 Personal history of allergy to penicillin	0.214	0.786
H33 Retinal detachments and breaks	0.219	0.781
Chapter XXII Codes for special purposes	0.221	0.779
H35 Other retinal disorders	0.225	0.775
Z09.2 Follow-up examination after chemotherapy for other conditions	0.225	0.775
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.226	0.774
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.231	0.769
Chapter X Diseases of the respiratory system	0.231	0.769
F40-F48 Neurotic, stress-related and somatoform disorders	0.269	0.731
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.270	0.730
Chapter XII Diseases of the skin and subcutaneous tissue	0.271	0.729
Z86.4 Personal history of psychoactive substance abuse	0.271	0.728
Z72 Problems related to lifestyle	0.278	0.722
E20-E35 Disorders of other endocrine glands	0.279	0.721
Chapter XV Pregnancy, childbirth and the puerperium	0.283	0.717
H25-H28 Disorders of lens	0.287	0.713
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.297	0.703
E10 Insulin-dependent diabetes mellitus	0.300	0.700
Z13 Special screening examination for other diseases and disorders	0.300	0.700
Z89 Acquired absence of limb	0.303	0.697
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.303	0.697
E11 Non-insulin-dependent diabetes mellitus	0.304	0.696
Z86.1 Personal history of infectious and parasitic diseases	0.304	0.696
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.304	0.696
Z86.6 Personal history of diseases of the nervous system and sense organs	0.305	0.695
Chapter I Certain infectious and parasitic diseases	0.307	0.693
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.309	0.691
Z95.8 Presence of other cardiac and vascular implants and grafts	0.310	0.690
T36-T50 Poisoning by drugs, medicaments and biological substances	0.311	0.689
Z09.8 Follow-up examination after other treatment for other conditions	0.312	0.688
Chapter VIII Diseases of the ear and mastoid process	0.312	0.687
Z72.0 Tobacco use	0.314	0.686
Z95.4 Presence of other heart-valve replacement	0.315	0.685
Z94 Transplanted organ and tissue status	0.318	0.682
Z83 Family history of other specific disorders	0.318	0.682
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system	0.318	0.682
Z97 Presence of other devices	0.318	0.682
H33.0 Retinal detachment with retinal break	0.319	0.681
E65-E68 Obesity and other hyperalimentation	0.320	0.680
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.321	0.679
Z95.1 Presence of aortocoronary bypass graft	0.322	0.678
H35.3 Degeneration of macula and posterior pole	0.323	0.677
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.324	0.676
W00-W19 Falls	0.328	0.672
H31 Other disorders of choroid	0.330	0.670
F41 Other anxiety disorders	0.330	0.670
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.336	0.664
H33.3 Retinal breaks without detachment	0.338	0.662
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.340	0.660
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.340	0.660
Z95.2 Presence of prosthetic heart valve	0.343	0.657
J40-J47 Chronic lower respiratory diseases	0.343	0.657
Z86.0 Personal history of other neoplasms	0.344	0.655
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances	0.345	0.655
Z85.3 Personal history of malignant neoplasm of breast	0.347	0.653
Chapter XVI Certain conditions originating in the perinatal period	0.348	0.652
Z09.0 Follow-up examination after surgery for other conditions	0.349	0.651
Z85.8 Personal history of malignant neoplasms of other organs and systems	0.356	0.644
H55-H59 Other disorders of eye and adnexa	0.356	0.644
Z93 Artificial opening status	0.358	0.642
H36 Retinal disorders in diseases classified elsewhere	0.359	0.640
Z03 Medical observation and evaluation for suspected diseases and conditions	0.360	0.639
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.363	0.637
Z81 Family history of mental and behavioural disorders	0.364	0.636
Z84 Family history of other conditions	0.365	0.635
Z00 General examination and investigation of persons without complaint or reported diagnosis	0.365	0.634
H43-H45 Disorders of vitreous body and globe	0.366	0.634
V40-V49 Car occupant injured in transport accident	0.368	0.632
L80-L99 Other disorders of the skin and subcutaneous tissue	0.368	0.632
H46-H48 Disorders of optic nerve and visual pathways	0.371	0.629
H53-H54 Visual disturbances and blindness	0.371	0.629
E70-E90 Metabolic disorders	0.371	0.629
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.372	0.628
Z88.3 Personal history of allergy to other anti-infective agents	0.374	0.626
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.375	0.625
E40-E46 Malnutrition	0.377	0.623
E50-E64 Other nutritional deficiencies	0.377	0.622
Z95.0 Presence of cardiac pacemaker	0.378	0.622
X60-X84 Intentional self-harm	0.378	0.622
S50-S59 Injuries to the elbow and forearm	0.379	0.621
F60-F69 Disorders of adult personality and behaviour	0.381	0.619
H35.8 Other specified retinal disorders	0.382	0.618
V10-V19 Pedal cyclist injured in transport accident	0.382	0.618
J30-J39 Other diseases of upper respiratory tract	0.382	0.618
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.382	0.618
F41.2 Mixed anxiety and depressive disorder	0.383	0.617
Z10 Routine general health check-up of defined subpopulation	0.383	0.617
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.385	0.615
H32 Chorioretinal disorders in diseases classified elsewhere	0.386	0.614
H40-H42 Glaucoma	0.386	0.614
Y00-Y09 Assault	0.386	0.614
V90-V94 Water transport accidents	0.388	0.612
H30 Chorioretinal inflammation	0.389	0.611
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.389	0.611
Z88.5 Personal history of allergy to narcotic agent	0.389	0.611
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.390	0.610
Z85.4 Personal history of malignant neoplasm of genital organs	0.390	0.610
Z11 Special screening examination for infectious and parasitic diseases	0.390	0.609
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.391	0.609
Z09.7 Follow-up examination after combined treatment for other conditions	0.393	0.607
H10-H13 Disorders of conjunctiva	0.393	0.607
Y60-Y69 Misadventures to patients during surgical and medical care	0.394	0.606
Z08 Follow-up examination after treatment for malignant neoplasm	0.394	0.606
Z98 Other postsurgical states	0.395	0.605
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.396	0.604
X50-X57 Overexertion, travel and privation	0.397	0.603
Z02 Examination and encounter for administrative purposes	0.397	0.603
V01-V09 Pedestrian injured in transport accident	0.398	0.602
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified	0.398	0.602
Y35-Y36 Legal intervention and operations of war	0.398	0.602
X85-X99 Assault	0.398	0.602
W65-W74 Accidental drowning and submersion	0.398	0.602
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.398	0.602
W50-W64 Exposure to animate mechanical forces	0.398	0.602
F80-F89 Disorders of psychological development	0.399	0.601
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.400	0.600
X30-X39 Exposure to forces of nature	0.400	0.600
V95-V97 Air and space transport accidents	0.400	0.600
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.400	0.600
Z04 Examination and observation for other reasons	0.400	0.600
H34 Retinal vascular occlusions	0.400	0.600
V70-V79 Bus occupant injured in transport accident	0.401	0.599
V98-V99 Other and unspecified transport accidents	0.401	0.599
Z86.3 Personal history of endocrine, nutritional and metabolic diseases	0.401	0.599
Z95.3 Presence of xenogenic heart valve	0.401	0.599
Y10-Y34 Event of undetermined intent	0.401	0.599
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.401	0.598
X00-X09 Exposure to smoke, fire and flames	0.402	0.598
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances	0.402	0.598
Z88.7 Personal history of allergy to serum and vaccine	0.403	0.597
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.403	0.597
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.404	0.596
E10.9 Without complications	0.405	0.595
W75-W84 Other accidental threats to breathing	0.405	0.595
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.405	0.595
J44 Other chronic obstructive pulmonary disease	0.405	0.595
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.405	0.594
F00-F09 Organic, including symptomatic, mental disorders	0.406	0.594
X20-X29 Contact with venomous animals and plants	0.406	0.594
Z09.3 Follow-up examination after psychotherapy	0.406	0.594
E14 Unspecified diabetes mellitus	0.406	0.594
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis	0.406	0.593
X10-X19 Contact with heat and hot substances	0.407	0.593
Z88.1 Personal history of allergy to other antibiotic agents	0.407	0.593
E24 Cushing's syndrome	0.409	0.591
H25 Senile cataract	0.409	0.591
V20-V29 Motorcycle rider injured in transport accident	0.409	0.591
Z86.5 Personal history of other mental and behavioural disorders	0.410	0.590
Z09.9 Follow-up examination after unspecified treatment for other conditions	0.410	0.590
Z09.4 Follow-up examination after treatment of fracture	0.410	0.590
Z09.1 Follow-up examination after radiotherapy for other conditions	0.410	0.590
S80-S89 Injuries to the knee and lower leg	0.410	0.590
X58-X59 Accidental exposure to other and unspecified factors	0.410	0.590
Z88.4 Personal history of allergy to anaesthetic agent	0.411	0.589
J95-J99 Other diseases of the respiratory system	0.411	0.589
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung	0.412	0.588
Y40 Systemic antibiotics	0.412	0.588
V80-V89 Other land transport accidents	0.413	0.587
H33.2 Serous retinal detachment	0.413	0.587
Z75 Problems related to medical facilities and other health care	0.414	0.586
J20-J22 Other acute lower respiratory infections	0.417	0.583
F99-F99 Unspecified mental disorder	0.417	0.583
U80 Agent resistant to penicillin and related antibiotics	0.417	0.583
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.419	0.581
Z91 Personal history of risk-factors, not elsewhere classified	0.420	0.580
F70-F79 Mental retardation	0.420	0.580
E13 Other specified diabetes mellitus	0.421	0.579
T15-T19 Effects of foreign body entering through natural orifice	0.422	0.578
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.422	0.577
Z73 Problems related to life-management difficulty	0.423	0.577
Z89.4 Acquired absence of foot and ankle	0.423	0.577
Z85.9 Personal history of malignant neoplasm, unspecified	0.423	0.577
X40-X49 Accidental poisoning by and exposure to noxious substances	0.424	0.576
W20-W49 Exposure to inanimate mechanical forces	0.424	0.575
E12 Malnutrition-related diabetes mellitus	0.425	0.575
Z85.6 Personal history of leukaemia	0.425	0.574
Z70 Counselling related to sexual attitude, behaviour and orientation	0.426	0.574
H35.2 Other proliferative retinopathy	0.429	0.571
S10-S19 Injuries to the neck	0.430	0.570
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.430	0.569
H35.5 Hereditary retinal dystrophy	0.431	0.569
T66-T78 Other and unspecified effects of external causes	0.431	0.569
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.432	0.568
H35.7 Separation of retinal layers	0.432	0.567
L20-L30 Dermatitis and eczema	0.433	0.567
Z85.0 Personal history of malignant neoplasm of digestive organs	0.433	0.567
E11.9 Without complications	0.434	0.566
Z82.5 Family history of asthma and other chronic lower respiratory diseases	0.435	0.565
H35.9 Retinal disorder, unspecified	0.435	0.565
O00-O08 Pregnancy with abortive outcome	0.435	0.565
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.436	0.564
Z85.5 Personal history of malignant neoplasm of urinary tract	0.437	0.563
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.439	0.561
Y86 Sequelae of other accidents	0.440	0.560
J80-J84 Other respiratory diseases principally affecting the interstitium	0.440	0.560
H60-H62 Diseases of external ear	0.440	0.560
H35.4 Peripheral retinal degeneration	0.441	0.559
Z76 Persons encountering health services in other circumstances	0.441	0.559
J60-J70 Lung diseases due to external agents	0.443	0.557
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified	0.443	0.557
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.443	0.557
H35.1 Retinopathy of prematurity	0.444	0.556
Z82.3 Family history of stroke	0.445	0.555
E66 Obesity	0.445	0.555
D50-D53 Nutritional anaemias	0.445	0.555
T00-T07 Injuries involving multiple body regions	0.445	0.555
T33-T35 Frostbite	0.445	0.555
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.445	0.555
T26-T28 Burns and corrosions confined to eye and internal organs	0.445	0.554
H33.4 Traction detachment of retina	0.446	0.554
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs	0.446	0.554
E10.3 With ophthalmic complications	0.447	0.553
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.447	0.553
H33.1 Retinoschisis and retinal cysts	0.447	0.553
H35.0 Background retinopathy and retinal vascular changes	0.448	0.552
Z37 Outcome of delivery	0.449	0.551
W19 Unspecified fall	0.449	0.551
Chapter VI Diseases of the nervous system	0.449	0.551
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified	0.449	0.551
Z13.5 Special screening examination for eye and ear disorders	0.449	0.551
Z74 Problems related to care-provider dependency	0.449	0.551
E11.4 With neurological complications	0.449	0.551
O60-O75 Complications of labour and delivery	0.449	0.550
E29 Testicular dysfunction	0.450	0.550
Z82.2 Family history of deafness and hearing loss	0.451	0.549
Z82.1 Family history of blindness and visual loss	0.451	0.549
A00-A09 Intestinal infectious diseases	0.451	0.548
F43 Reaction to severe stress, and adjustment disorders	0.452	0.548
Y52 Agents primarily affecting the cardiovascular system	0.452	0.548
H80-H83 Diseases of inner ear	0.452	0.548
Z60 Problems related to social environment	0.452	0.548
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.455	0.545
F42 Obsessive-compulsive disorder	0.456	0.544
Z94.8 Other transplanted organ and tissue status	0.456	0.544
H33.5 Other retinal detachments	0.457	0.543
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities	0.457	0.543
H35.6 Retinal haemorrhage	0.457	0.543
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue	0.457	0.543
J00-J06 Acute upper respiratory infections	0.458	0.542
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.459	0.541
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.460	0.540
E11.3 With ophthalmic complications	0.460	0.540
Z22 Carrier of infectious disease	0.460	0.540
E22 Hyperfunction of pituitary gland	0.460	0.540
T79-T79 Certain early complications of trauma	0.460	0.539
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.461	0.539
S90-S99 Injuries to the ankle and foot	0.461	0.539
A30-A49 Other bacterial diseases	0.462	0.538
J90-J94 Other diseases of pleura	0.463	0.537
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.463	0.537
S70-S79 Injuries to the hip and thigh	0.463	0.536
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.464	0.536
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.464	0.536
E27 Other disorders of adrenal gland	0.464	0.536
Z57 Occupational exposure to risk-factors	0.464	0.535
Z82.0 Family history of epilepsy and other diseases of the nervous system	0.465	0.535
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.466	0.534
S00-S09 Injuries to the head	0.468	0.532
D55-D59 Haemolytic anaemias	0.469	0.531
L40-L45 Papulosquamous disorders	0.469	0.531
E23 Hypofunction and other disorders of pituitary gland	0.470	0.530
S20-S29 Injuries to the thorax	0.470	0.530
L60-L75 Disorders of skin appendages	0.470	0.530
E00-E07 Disorders of thyroid gland	0.470	0.530
E11.5 With peripheral circulatory complications	0.470	0.530
T20-T25 Burns and corrosions of external body surface, specified by site	0.472	0.528
E10.4 With neurological complications	0.474	0.526
Z72.2 Drug use	0.474	0.526
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.476	0.524
Z83.5 Family history of eye and ear disorders	0.476	0.524
B25-B34 Other viral diseases	0.477	0.523
D80-D89 Certain disorders involving the immune mechanism	0.477	0.523
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.477	0.522
L50-L54 Urticaria and erythema	0.477	0.522
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.478	0.522
D70-D77 Other diseases of blood and blood-forming organs	0.478	0.521
H02 Other disorders of eyelid	0.479	0.521
E34 Other endocrine disorders	0.479	0.521
E78.0 Pure hypercholesterolaemia	0.479	0.521
B15-B19 Viral hepatitis	0.479	0.520
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent	0.480	0.520
F48 Other neurotic disorders	0.480	0.520
Z88.2 Personal history of allergy to sulphonamides	0.480	0.519
T46 Poisoning by agents primarily affecting the cardiovascular system	0.482	0.518
D69 Purpura and other haemorrhagic conditions	0.482	0.518
Y43 Primarily systemic agents	0.482	0.518
Z72.3 Lack of physical exercise	0.482	0.518
Z72.5 High-risk sexual behaviour	0.483	0.517
Z72.6 Gambling and betting	0.483	0.517
E35 Disorders of endocrine glands in diseases classified elsewhere	0.483	0.517
E30 Disorders of puberty, not elsewhere classified	0.483	0.517
F44 Dissociative [conversion] disorders	0.483	0.517
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.483	0.517
Z72.9 Problem related to lifestyle, unspecified	0.483	0.516
H31.3 Choroidal haemorrhage and rupture	0.483	0.516
A50-A64 Infections with a predominantly sexual mode of transmission	0.483	0.516
E31 Polyglandular dysfunction	0.484	0.516
J44.9 Chronic obstructive pulmonary disease, unspecified	0.484	0.516
E32 Diseases of thymus	0.484	0.516
E25 Adrenogenital disorders	0.484	0.516
Z63 Other problems related to primary support group, including family circumstances	0.484	0.516
H26 Other cataract	0.484	0.515
Z72.4 Inappropriate diet and eating habits	0.484	0.515
T85 Complications of other internal prosthetic devices, implants and grafts	0.485	0.515
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues	0.485	0.515
Z72.8 Other problems related to lifestyle	0.485	0.514
L10-L14 Bullous disorders	0.486	0.514
Z21 Asymptomatic human immunodeficiency virus [HIV] infection status	0.486	0.514
F40 Phobic anxiety disorders	0.487	0.513
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.487	0.512
E28 Ovarian dysfunction	0.487	0.513
E20 Hypoparathyroidism	0.487	0.512
E10.5 With peripheral circulatory complications	0.488	0.512
Z88.6 Personal history of allergy to analgesic agent	0.488	0.512
Y41 Other systemic anti-infectives and antiparasitics	0.488	0.512
O80-O84 Delivery	0.488	0.512
F30-F39 Mood [affective] disorders	0.488	0.512
E26 Hyperaldosteronism	0.489	0.511
H28 Cataract and other disorders of lens in diseases classified elsewhere	0.490	0.510
W06 Fall involving bed	0.490	0.510
F45 Somatoform disorders	0.490	0.510
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.491	0.509
H27 Other disorders of lens	0.491	0.509
U80.1 Methicillin resistant agent	0.491	0.509
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.492	0.508
S40-S49 Injuries to the shoulder and upper arm	0.492	0.508
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.493	0.507
H04 Disorders of lachrymal system	0.493	0.506
Z97.3 Presence of spectacles and contact lenses	0.494	0.505
Z97.2 Presence of dental prosthetic device (complete)(partial)	0.495	0.505
Z83.2 Family history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.495	0.505
Z62 Other problems related to upbringing	0.495	0.504
Z55 Problems related to education and literacy	0.495	0.504
B20-B24 Human immunodeficiency virus [HIV] disease	0.496	0.504
Z13.6 Special screening examination for cardiovascular disorders	0.496	0.504
Z97.8 Presence of other specified devices	0.496	0.503
J32 Chronic sinusitis	0.497	0.503
O94-O99 Other obstetric conditions, not elsewhere classified	0.498	0.502
Z65 Problems related to other psychosocial circumstances	0.498	0.502
O85-O92 Complications predominantly related to the puerperium	0.498	0.502
Z13.4 Special screening examination for certain developmental disorders in childhood	0.498	0.502
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.498	0.501
Z13.8 Special screening examination for other specified diseases and disorders	0.499	0.501
Z61 Problems related to negative life events in childhood	0.499	0.501
E10.7 With multiple complications	0.499	0.501
B90-B94 Sequelae of infectious and parasitic diseases	0.499	0.501
Z64 Problems related to certain psychosocial circumstances	0.499	0.501
Z13.7 Special screening examination for congenital malformations, deformations and chromosomal abnormalities	0.499	0.501
Y49 Psychotropic drugs, not elsewhere classified	0.500	0.500
Z83.3 Family history of diabetes mellitus	0.500	0.500
Z12 Special screening examination for neoplasms	0.500	0.500
Z89.3 Acquired absence of both upper limbs [any level]	0.500	0.500
Z89.1 Acquired absence of hand and wrist	0.500	0.500
Z13.2 Special screening examination for nutritional disorders	0.500	0.500
Z93.5 Cystostomy status	0.500	0.500
F10 Mental and behavioural disorders due to use of alcohol	0.500	0.500
Z28 Immunisation not carried out	0.500	0.499
Z25 Need for immunisation against other single viral diseases	0.500	0.499
Z23 Need for immunisation against single bacterial diseases	0.500	0.499
E11.2 With renal complications	0.500	0.499
Z27 Need for immunisation against combinations of infectious diseases	0.501	0.499
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.501	0.499
H00 Hordeolum and chalazion	0.501	0.499
Z26 Need for immunisation against other single infectious diseases	0.501	0.499
Z89.8 Acquired absence of upper and lower limbs [any level]	0.501	0.499
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.501	0.499
E11.7 With multiple complications	0.501	0.499
E10.6 With other specified complications	0.501	0.499
E10.1 With ketoacidosis	0.501	0.499
Z24 Need for immunisation against certain single viral diseases	0.501	0.498
E10.0 With coma	0.502	0.498
E10.8 With unspecified complications	0.502	0.498
H31.1 Choroidal degeneration	0.502	0.498
Z93.6 Other artificial openings of urinary tract status	0.502	0.498
Z89.9 Acquired absence of limb, unspecified	0.502	0.498
W13 Fall from, out of or through building or structure	0.502	0.497
Z89.7 Acquired absence of both lower limbs [any level, except toes alone]	0.502	0.497
F41.9 Anxiety disorder, unspecified	0.503	0.497
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.503	0.497
A75-A79 Rickettsioses	0.503	0.497
A70-A74 Other diseases caused by chlamydiae	0.503	0.497
Z89.2 Acquired absence of upper limb above wrist	0.503	0.497
Z20 Contact with and exposure to communicable diseases	0.503	0.497
Z96 Presence of other functional implants	0.503	0.497
L90 Atrophic disorders of skin	0.503	0.497
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.503	0.497
A20-A28 Certain zoonotic bacterial diseases	0.504	0.496
B85-B89 Pediculosis, acariasis and other infestations	0.504	0.496
Z59 Problems related to housing and economic circumstances	0.504	0.495
Z58 Problems related to physical environment	0.505	0.495
Y50 Central nervous system stimulants, not elsewhere classified	0.505	0.495
Z89.0 Acquired absence of finger(s) [including thumb], unilateral	0.505	0.495
Z13.3 Special screening examination for mental and behavioural disorders	0.505	0.495
F41.0 Panic disorder [episodic paroxysmal anxiety]	0.505	0.495
Y58 Bacterial vaccines	0.505	0.495
A65-A69 Other spirochaetal diseases	0.506	0.494
E10.2 With renal complications	0.506	0.494
H05 Disorders of orbit	0.506	0.494
Z56 Problems related to employment and unemployment	0.506	0.494
T41 Poisoning by anaesthetics and therapeutic gases	0.506	0.494
Y47 Sedatives, hypnotics and antianxiety drugs	0.506	0.494
Z03.4 Observation for suspected myocardial infarction	0.506	0.494
E11.8 With unspecified complications	0.506	0.494
Y59 Other and unspecified vaccines and biological substances	0.506	0.493
H31.0 Chorioretinal scars	0.507	0.493
Z94.0 Kidney transplant status	0.507	0.493
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.507	0.493
W15 Fall from cliff	0.507	0.493
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.507	0.493
Z29 Need for other prophylactic measures	0.508	0.492
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.508	0.492
E11.0 With coma	0.508	0.492
Z97.5 Presence of (intra-uterine) contraceptive device	0.508	0.491
B99-B99 Other infectious diseases	0.509	0.491
A15-A19 Tuberculosis	0.509	0.491
B50-B64 Protozoal diseases	0.509	0.491
E11.6 With other specified complications	0.509	0.490
B65-B83 Helminthiases	0.510	0.490
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.510	0.490
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.511	0.489
Z83.0 Family history of human immunodeficiency virus [HIV]	0.511	0.489
T36 Poisoning by systemic antibiotics	0.511	0.489
S50 Superficial injury of forearm	0.511	0.489
E11.1 With ketoacidosis	0.511	0.489
Z89.6 Acquired absence of leg above knee	0.511	0.489
Z37.0 Single live birth	0.511	0.489
T87 Complications peculiar to reattachment and amputation	0.511	0.489
Z94.3 Heart and lungs transplant status	0.511	0.488
Z94.9 Transplanted organ and tissue status, unspecified	0.511	0.488
Z94.6 Bone transplant status	0.511	0.488
W02 Fall involving ice-skates, skis, roller-skates or skateboards	0.511	0.488
Z03.9 Observation for suspected disease or condition, unspecified	0.511	0.488
Y53 Agents primarily affecting the gastro-intestinal system	0.512	0.488
Z94.5 Skin transplant status	0.512	0.488
E67 Other hyperalimentation	0.512	0.488
E68 Sequelae of hyperalimentation	0.512	0.488
Z03.2 Observation for suspected mental and behavioural disorders	0.512	0.488
Y48 Anaesthetics and therapeutic gases	0.513	0.487
V48 Car occupant injured in noncollision transport accident	0.513	0.487
Y46 Antiepileptics and anti-Parkinsonism drugs	0.513	0.486
J47 Bronchiectasis	0.513	0.486
Z97.1 Presence of artificial limb (complete)(partial)	0.514	0.486
Z94.2 Lung transplant status	0.514	0.486
Y57 Other and unspecified drugs and medicaments	0.514	0.486
Z83.6 Family history of diseases of the respiratory system	0.514	0.486
L98.8 Other specified disorders of skin and subcutaneous tissue	0.514	0.486
F41.1 Generalised anxiety disorder	0.514	0.486
Z83.1 Family history of other infectious and parasitic diseases	0.514	0.486
H36.0 Diabetic retinopathy	0.514	0.485
J46 Status asthmaticus	0.515	0.485
J42 Unspecified chronic bronchitis	0.515	0.485
Z97.4 Presence of external hearing-aid	0.515	0.485
W17 Other fall from one level to another	0.515	0.485
Z94.1 Heart transplant status	0.515	0.485
Z89.5 Acquired absence of leg at or below knee	0.515	0.484
A80-A89 Viral infections of the central nervous system	0.516	0.484
H03 Disorders of eyelid in diseases classified elsewhere	0.516	0.484
J33 Nasal polyp	0.516	0.484
J41 Simple and mucopurulent chronic bronchitis	0.516	0.484
L81 Other disorders of pigmentation	0.516	0.483
T80 Complications following infusion, transfusion and therapeutic injection	0.517	0.482
W04 Fall while being carried or supported by other persons	0.518	0.482
Z97.0 Presence of artificial eye	0.518	0.482
W16 Diving or jumping into water causing injury other than drowning or submersion	0.519	0.481
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.519	0.481
W12 Fall on and from scaffolding	0.519	0.481
Z00.5 Examination of potential donor of organ and tissue	0.519	0.481
Y89 Sequelae of other external causes	0.519	0.481
W09 Fall involving playground equipment	0.519	0.480
H31.4 Choroidal detachment	0.519	0.480
H31.2 Hereditary choroidal dystrophy	0.519	0.480
Z13.1 Special screening examination for diabetes mellitus	0.520	0.480
W00 Fall on same level involving ice and snow	0.520	0.480
W10 Fall on and from stairs and steps	0.520	0.480
Z94.4 Liver transplant status	0.520	0.480
E65 Localised adiposity	0.520	0.480
Z94.7 Corneal transplant status	0.520	0.480
H31.9 Disorder of choroid, unspecified	0.520	0.479
W14 Fall from tree	0.521	0.479
F41.3 Other mixed anxiety disorders	0.521	0.479
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.521	0.478
F41.8 Other specified anxiety disorders	0.522	0.478

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations