TreeWAS – Variant ID: rs2278702

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.655	0.345	0.000
I80 Phlebitis and thrombophlebitis	0.601	0.399	0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.592	0.408	0.000
I80.8 Phlebitis and thrombophlebitis of other sites	0.471	0.529	0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.455	0.545	0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.439	0.561	0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.309	0.691	0.000
C16.9 Stomach, unspecified	0.202	0.798	0.000
C16 Malignant neoplasm of stomach	0.199	0.801	0.000
C16.0 Cardia	0.194	0.806	0.000
C16.3 Pyloric antrum	0.161	0.839	0.000
C16.4 Pylorus	0.159	0.841	0.000
C16.5 Lesser curvature of stomach, unspecified	0.158	0.842	0.000
C16.1 Fundus of stomach	0.150	0.850	0.000
C16.8 Overlapping lesion of stomach	0.143	0.857	0.000
C15-C26 Malignant neoplasms of digestive organs	0.143	0.857	0.000
C16.6 Greater curvature of stomach, unspecified	0.137	0.863	0.000
C15 Malignant neoplasm of oesophagus	0.133	0.867	0.000
C25 Malignant neoplasm of pancreas	0.133	0.867	0.000
C16.2 Body of stomach	0.132	0.868	0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.124	0.876	0.000
C17 Malignant neoplasm of small intestine	0.120	0.880	0.000
C25.9 Pancreas, unspecified	0.118	0.882	0.000
C25.0 Head of pancreas	0.116	0.884	0.000
C15.9 Oesophagus, unspecified	0.113	0.887	0.000
C15.4 Middle third of oesophagus	0.113	0.887	0.000
C19 Malignant neoplasm of rectosigmoid junction	0.112	0.888	0.000
C25.7 Other parts of pancreas	0.108	0.892	0.000
C15.3 Upper third of oesophagus	0.107	0.893	0.000
C24.0 Extrahepatic bile duct	0.102	0.897	0.000
R35 Polyuria	0.101	0.899	0.000
C24.9 Biliary tract, unspecified	0.101	0.899	0.000
C15.5 Lower third of oesophagus	0.101	0.899	0.000
C17.1 Jejunum	0.099	0.901	0.000
C21 Malignant neoplasm of anus and anal canal	0.097	0.903	0.000
C15.8 Overlapping lesion of oesophagus	0.096	0.904	0.000
C15.2 Abdominal part of oesophagus	0.096	0.904	0.000
C15.1 Thoracic part of oesophagus	0.096	0.904	0.000
C15.0 Cervical part of oesophagus	0.096	0.904	0.000
C17.0 Duodenum	0.096	0.904	0.000
C23 Malignant neoplasm of gallbladder	0.096	0.904	0.000
C25.8 Overlapping lesion of pancreas	0.095	0.904	0.000
C25.4 Endocrine pancreas	0.095	0.904	0.000
C25.3 Pancreatic duct	0.094	0.906	0.000
C24.1 Ampulla of Vater	0.093	0.907	0.000
C26 Malignant neoplasm of other and ill-defined digestive organs	0.092	0.908	0.000
C17.9 Small intestine, unspecified	0.090	0.910	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.090	0.910	0.000
C24.8 Overlapping lesion of biliary tract	0.089	0.911	0.000
C25.1 Body of pancreas	0.088	0.912	0.000
C25.2 Tail of pancreas	0.086	0.913	0.000
C17.8 Overlapping lesion of small intestine	0.086	0.914	0.000
C17.3 Meckel's diverticulum	0.086	0.914	0.000
C17.2 Ileum	0.079	0.921	0.000
C22.9 Liver, unspecified	0.072	0.928	0.000
C21.1 Anal canal	0.070	0.930	0.000
C21.2 Cloacogenic zone	0.069	0.930	0.000
C26.9 Ill-defined sites within the digestive system	0.069	0.931	0.000
C21.8 Overlapping lesion of rectum, anus and anal canal	0.067	0.933	0.000
C21.0 Anus, unspecified	0.066	0.934	0.000
C26.8 Overlapping lesion of digestive system	0.066	0.934	0.000
C26.1 Spleen	0.066	0.934	0.000
C22.1 Intrahepatic bile duct carcinoma	0.065	0.935	0.000
C22.7 Other specified carcinomas of liver	0.065	0.935	0.000
C22.4 Other sarcomas of liver	0.065	0.935	0.000
C22.3 Angiosarcoma of liver	0.065	0.935	0.000
C22.2 Hepatoblastoma	0.065	0.935	0.000
C26.0 Intestinal tract, part unspecified	0.051	0.949	0.000
C22.0 Liver cell carcinoma	0.038	0.962	0.000
S02.60 Fracture of mandible (closed)	0.035	0.965	0.000
S02.40 Fracture of malar and maxillary bones (closed)	0.034	0.966	0.000
S02.6 Fracture of mandible	0.034	0.966	0.000
S02.4 Fracture of malar and maxillary bones	0.033	0.967	0.000
S02 Fracture of skull and facial bones	0.033	0.967	0.000
S02.8 Fractures of other skull and facial bones	0.029	0.971	0.000
S02.1 Fracture of base of skull	0.028	0.972	0.000
S02.0 Fracture of vault of skull	0.026	0.974	0.000
S02.80 Fractures of other skull and facial bones (closed)	0.026	0.974	0.000
S02.10 Fracture of base of skull (closed)	0.025	0.975	0.000
S02.61 Fracture of mandible (open)	0.024	0.976	0.000
S02.7 Multiple fractures involving skull and facial bones	0.024	0.976	0.000
S02.41 Fracture of malar and maxillary bones (open)	0.024	0.976	0.000
C20 Malignant neoplasm of rectum	0.023	0.977	0.000
S02.3 Fracture of orbital floor	0.023	0.977	0.000
S02.5 Fracture of tooth	0.022	0.978	0.000
S02.9 Fracture of skull and facial bones, part unspecified	0.022	0.978	0.000
S02.00 Fracture of vault of skull (closed)	0.022	0.978	0.000
S02.81 Fractures of other skull and facial bones (open)	0.021	0.979	0.000
S02.2 Fracture of nasal bones	0.021	0.979	0.000
Z88.1 Personal history of allergy to other antibiotic agents	0.020	0.980	0.000
S02.11 Fracture of base of skull (open)	0.020	0.980	0.000
S02.01 Fracture of vault of skull (open)	0.019	0.981	0.000
S02.70 Multiple fractures involving skull and facial bones (closed)	0.018	0.982	0.000
S02.71 Multiple fractures involving skull and facial bones (open)	0.017	0.982	0.000
S02.31 Fracture of orbital floor (open)	0.016	0.983	0.000
H65.3 Chronic mucoid otitis media	0.000	0.984	0.016
S02.51 Fracture of tooth (open)	0.016	0.984	0.000
S02.91 Fracture of skull and facial bones, part unspecified (open)	0.016	0.984	0.000
S02.30 Fracture of orbital floor (closed)	0.015	0.985	0.000
S02.21 Fracture of nasal bones (open)	0.015	0.985	0.000
H65 Nonsuppurative otitis media	0.000	0.985	0.015
S02.50 Fracture of tooth (closed)	0.014	0.985	0.000
S02.90 Fracture of skull and facial bones, part unspecified (closed)	0.014	0.986	0.000
H65.4 Other chronic nonsuppurative otitis media	0.000	0.986	0.014
H65.9 Nonsuppurative otitis media, unspecified	0.000	0.987	0.013
S02.20 Fracture of nasal bones (closed)	0.012	0.988	0.000
J32.9 Chronic sinusitis, unspecified	0.012	0.988	0.000
H65.1 Other acute nonsuppurative otitis media	0.000	0.989	0.011
H65-H75 Diseases of middle ear and mastoid	0.000	0.989	0.011
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.010	0.990	0.000
H71 Cholesteatoma of middle ear	0.000	0.990	0.010
H65.0 Acute serous otitis media	0.000	0.990	0.009
I82 Other venous embolism and thrombosis	0.009	0.991	0.000
H69 Other disorders of Eustachian tube	0.000	0.991	0.009
H74 Other disorders of middle ear and mastoid	0.000	0.991	0.009
H73 Other disorders of tympanic membrane	0.000	0.991	0.009
H65.2 Chronic serous otitis media	0.000	0.991	0.009
R03.1 Nonspecific low blood-pressure reading	0.009	0.991	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.000	0.992	0.008
I82.2 Embolism and thrombosis of vena cava	0.008	0.992	0.000
H70 Mastoiditis and related conditions	0.000	0.992	0.008
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.000	0.992	0.008
H68 Eustachian salpingitis and obstruction	0.000	0.992	0.008
H67 Otitis media in diseases classified elsewhere	0.000	0.992	0.008
I89.0 Lymphoedema, not elsewhere classified	0.008	0.992	0.000
H69.8 Other specified disorders of Eustachian tube	0.000	0.992	0.007
I82.3 Embolism and thrombosis of renal vein	0.007	0.992	0.000
I81 Portal vein thrombosis	0.007	0.993	0.000
H73.8 Other specified disorders of tympanic membrane	0.000	0.993	0.007
H69.9 Eustachian tube disorder, unspecified	0.000	0.993	0.007
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.007	0.993	0.000
I88 Nonspecific lymphadenitis	0.007	0.993	0.000
I82.9 Embolism and thrombosis of unspecified vein	0.007	0.993	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.000	0.993	0.007
H74.4 Polyp of middle ear	0.000	0.993	0.007
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.007	0.993	0.000
I82.1 Thrombophlebitis migrans	0.007	0.993	0.000
I82.0 Budd-Chiari syndrome	0.007	0.993	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.000	0.993	0.007
H74.1 Adhesive middle ear disease	0.000	0.993	0.007
H69.0 Patulous Eustachian tube	0.000	0.993	0.007
H74.2 Discontinuity and dislocation of ear ossicles	0.000	0.993	0.007
H73.1 Chronic myringitis	0.000	0.993	0.006
H73.0 Acute myringitis	0.000	0.993	0.006
I82.8 Embolism and thrombosis of other specified veins	0.006	0.994	0.000
H70.9 Mastoiditis, unspecified	0.000	0.994	0.006
H72 Perforation of tympanic membrane	0.000	0.994	0.006
R30.0 Dysuria	0.006	0.994	0.000
A08.4 Viral intestinal infection, unspecified	0.006	0.994	0.000
H74.0 Tympanosclerosis	0.000	0.994	0.006
H70.8 Other mastoiditis and related conditions	0.000	0.994	0.006
H70.2 Petrositis	0.000	0.994	0.006
H70.1 Chronic mastoiditis	0.000	0.994	0.006
H70.0 Acute mastoiditis	0.000	0.994	0.006
G35 Multiple sclerosis	0.006	0.994	0.000
I86 Varicose veins of other sites	0.006	0.994	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.000	0.994	0.006
H67.1 Otitis media in viral diseases classified elsewhere	0.000	0.994	0.006
H67.0 Otitis media in bacterial diseases classified elsewhere	0.000	0.994	0.006
H68.1 Obstruction of Eustachian tube	0.000	0.994	0.006
H68.0 Eustachian salpingitis	0.000	0.994	0.006
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.000	0.994	0.006
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.000	0.994	0.006
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems	0.006	0.994	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.994	0.006
H74.9 Disorder of middle ear and mastoid, unspecified	0.000	0.994	0.005
I88.8 Other nonspecific lymphadenitis	0.005	0.994	0.000
I88.1 Chronic lymphadenitis, except mesenteric	0.005	0.994	0.000
I88.0 Nonspecific mesenteric lymphadenitis	0.005	0.994	0.000
I88.9 Nonspecific lymphadenitis, unspecified	0.005	0.995	0.000
H72.0 Central perforation of tympanic membrane	0.000	0.995	0.005
H72.8 Other perforations of tympanic membrane	0.000	0.995	0.005
I86.1 Scrotal varices	0.005	0.995	0.000
H72.1 Attic perforation of tympanic membrane	0.000	0.995	0.005
S00-S09 Injuries to the head	0.005	0.995	0.000
R30 Pain associated with micturition	0.005	0.995	0.000
I86.3 Vulval varices	0.004	0.995	0.000
I86.2 Pelvic varices	0.004	0.995	0.000
I86.0 Sublingual varices	0.004	0.995	0.000
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified	0.004	0.995	0.000
N87.0 Mild cervical dysplasia	0.004	0.996	0.000
C18 Malignant neoplasm of colon	0.004	0.996	0.000
M89.9 Disorder of bone, unspecified	0.004	0.996	0.000
H66 Suppurative and unspecified otitis media	0.000	0.996	0.004
Z13.9 Special screening examination, unspecified	0.004	0.996	0.000
I85 Oesophageal varices	0.003	0.996	0.001
S06 Intracranial injury	0.004	0.996	0.000
I86.8 Varicose veins of other specified sites	0.004	0.996	0.000
R30-R39 Symptoms and signs involving the urinary system	0.004	0.996	0.000
O46.9 Antepartum haemorrhage, unspecified	0.000	0.996	0.004
S05 Injury of eye and orbit	0.004	0.996	0.000
S05.8 Other injuries of eye and orbit	0.004	0.996	0.000
H72.2 Other marginal perforations of tympanic membrane	0.000	0.996	0.004
S06.0 Concussion	0.004	0.996	0.000
N87.1 Moderate cervical dysplasia	0.004	0.996	0.000
I87 Other disorders of veins	0.004	0.996	0.000
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes	0.004	0.996	0.000
S06.2 Diffuse brain injury	0.004	0.996	0.000
S06.00 Concussion (without open intracranial wound)	0.004	0.996	0.000
S03 Dislocation, sprain and strain of joints and ligaments of head	0.004	0.996	0.000
C18.8 Overlapping lesion of colon	0.004	0.996	0.000
E87.5 Hyperkalaemia	0.000	0.996	0.004
S06.5 Traumatic subdural haemorrhage	0.004	0.996	0.000
Z96.1 Presence of intraocular lens	0.000	0.996	0.004
C18.0 Caecum	0.004	0.996	0.000
S08 Traumatic amputation of part of head	0.003	0.996	0.000
S07 Crushing injury of head	0.003	0.996	0.000
S04 Injury of cranial nerves	0.003	0.996	0.000
M89.98 Disorder of bone, unspecified (Other)	0.003	0.996	0.000
S06.20 Diffuse brain injury (without open intracranial wound)	0.004	0.996	0.000
M89.8 Other specified disorders of bone	0.004	0.996	0.000
M89.91 Disorder of bone, unspecified (Shoulder region)	0.003	0.996	0.000
R30.1 Vesical tenesmus	0.003	0.996	0.000
S06.1 Traumatic cerebral oedema	0.003	0.996	0.000
S05.1 Contusion of eyeball and orbital tissues	0.003	0.996	0.000
H66.4 Suppurative otitis media, unspecified	0.000	0.996	0.003
M89.96 Disorder of bone, unspecified (Lower leg)	0.003	0.996	0.000
I89.1 Lymphangitis	0.003	0.997	0.001
S06.8 Other intracranial injuries	0.003	0.997	0.000
M89.99 Disorder of bone, unspecified (Site unspecified)	0.003	0.997	0.000
M89.93 Disorder of bone, unspecified (Forearm)	0.003	0.997	0.000
M89.92 Disorder of bone, unspecified (Upper arm)	0.003	0.997	0.000
M89.90 Disorder of bone, unspecified (Multiple sites)	0.003	0.997	0.000
C18.1 Appendix	0.003	0.997	0.000
M89.88 Other specified disorders of bone (Other)	0.003	0.997	0.000
M89.87 Other specified disorders of bone (Ankle and foot)	0.003	0.997	0.000
U80.1 Methicillin resistant agent	0.000	0.997	0.003
R32 Unspecified urinary incontinence	0.003	0.997	0.000
S06.7 Intracranial injury with prolonged coma	0.003	0.997	0.000
C18.5 Splenic flexure	0.003	0.997	0.000
H66.0 Acute suppurative otitis media	0.000	0.997	0.003
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.003	0.997	0.000
M89 Other disorders of bone	0.003	0.997	0.000
S03.2 Dislocation of tooth	0.003	0.997	0.000
S06.9 Intracranial injury, unspecified	0.003	0.997	0.000
N87 Dysplasia of cervix uteri	0.003	0.997	0.000
S05.7 Avulsion of eye	0.003	0.997	0.000
S05.6 Penetrating wound of eyeball without foreign body	0.003	0.997	0.000
S05.5 Penetrating wound of eyeball with foreign body	0.003	0.997	0.000
S05.4 Penetrating wound of orbit with or without foreign body	0.003	0.997	0.000
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue	0.003	0.997	0.000
M25.46 Effusion of joint (Lower leg)	0.000	0.997	0.003
S06.4 Epidural haemorrhage	0.003	0.997	0.000
Z74.8 Other problems related to care-provider dependency	0.003	0.997	0.000
S06.01 Concussion (with open intracranial wound)	0.003	0.997	0.000
I87.9 Disorder of vein, unspecified	0.003	0.997	0.000
I87.0 Postphlebitic syndrome	0.003	0.997	0.000
M89.85 Other specified disorders of bone (Pelvic region and thigh)	0.003	0.997	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.000	0.997	0.003
N87.2 Severe cervical dysplasia, not elsewhere classified	0.003	0.997	0.000
K63.3 Ulcer of intestine	0.000	0.997	0.003
Z74 Problems related to care-provider dependency	0.003	0.997	0.000
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.003	0.997	0.000
S06.21 Diffuse brain injury (with open intracranial wound)	0.003	0.997	0.000
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body	0.003	0.997	0.000
S03.5 Sprain and strain of joints and ligaments of other and unspecified parts of head	0.003	0.997	0.000
S03.4 Sprain and strain of jaw	0.003	0.997	0.000
S03.3 Dislocation of other and unspecified parts of head	0.003	0.997	0.000
S03.1 Dislocation of septal cartilage of nose	0.003	0.997	0.000
S03.0 Dislocation of jaw	0.003	0.997	0.000
Z74.2 Need for assistance at home and no other household member able to render care	0.003	0.997	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.000	0.997	0.003
H72.9 Perforation of tympanic membrane, unspecified	0.000	0.997	0.003
Z74.0 Reduced mobility	0.003	0.997	0.000
M89.81 Other specified disorders of bone (Shoulder region)	0.003	0.997	0.000
J32.4 Chronic pansinusitis	0.003	0.997	0.000
A08 Viral and other specified intestinal infections	0.003	0.997	0.000
S05.3 Ocular laceration without prolapse or loss of intraocular tissue	0.003	0.997	0.000
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.003	0.997	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.003	0.997	0.000
Z74.9 Problem related to care-provider dependency, unspecified	0.003	0.997	0.000
J32 Chronic sinusitis	0.003	0.997	0.000
I87.2 Venous insufficiency (chronic) (peripheral)	0.003	0.997	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.003	0.997	0.000
M89.84 Other specified disorders of bone (Hand)	0.003	0.997	0.000
M89.89 Other specified disorders of bone (Site unspecified)	0.003	0.997	0.000
M89.83 Other specified disorders of bone (Forearm)	0.003	0.997	0.000
M89.82 Other specified disorders of bone (Upper arm)	0.003	0.997	0.000
M89.80 Other specified disorders of bone (Multiple sites)	0.003	0.997	0.000
S04.9 Injury of unspecified cranial nerve	0.003	0.997	0.000
S04.8 Injury of other cranial nerves	0.003	0.997	0.000
S04.7 Injury of accessory nerve	0.003	0.997	0.000
S04.6 Injury of acoustic nerve	0.003	0.997	0.000
S04.5 Injury of facial nerve	0.003	0.997	0.000
S04.4 Injury of abducent nerve	0.003	0.997	0.000
S04.3 Injury of trigeminal nerve	0.003	0.997	0.000
S04.2 Injury of trochlear nerve	0.003	0.997	0.000
S04.1 Injury of oculomotor nerve	0.003	0.997	0.000
S04.0 Injury of optic nerve and pathways	0.003	0.997	0.000
S07.9 Crushing injury of head, part unspecified	0.003	0.997	0.000
S07.8 Crushing injury of other parts of head	0.003	0.997	0.000
S07.1 Crushing injury of skull	0.003	0.997	0.000
S07.0 Crushing injury of face	0.003	0.997	0.000
S08.9 Traumatic amputation of unspecified part of head	0.003	0.997	0.000
S08.8 Traumatic amputation of other parts of head	0.003	0.997	0.000
S08.1 Traumatic amputation of ear	0.003	0.997	0.000
S08.0 Avulsion of scalp	0.003	0.997	0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.003	0.997	0.000
I85.0 Oesophageal varices with bleeding	0.002	0.997	0.001
S06.80 Other intracranial injuries (without open intracranial wound)	0.003	0.997	0.000
S06.3 Focal brain injury	0.002	0.997	0.000
S06.81 Other intracranial injuries (with open intracranial wound)	0.003	0.997	0.000
J93.8 Other pneumothorax	0.000	0.997	0.003
K74.6 Other and unspecified cirrhosis of liver	0.000	0.997	0.003
R36 Urethral discharge	0.003	0.997	0.000
J93.9 Pneumothorax, unspecified	0.000	0.997	0.003
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)	0.002	0.997	0.000
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)	0.002	0.997	0.000
H66.3 Other chronic suppurative otitis media	0.000	0.997	0.003
S05.9 Injury of eye and orbit, part unspecified	0.002	0.997	0.000
M13.91 Arthritis, unspecified (Shoulder region)	0.003	0.997	0.000
M89.86 Other specified disorders of bone (Lower leg)	0.003	0.997	0.000
U80 Agent resistant to penicillin and related antibiotics	0.000	0.997	0.003
M89.6 Osteopathy after poliomyelitis	0.002	0.997	0.000
M89.4 Other hypertrophic osteo-arthropathy	0.002	0.997	0.000
M89.2 Other disorders of bone development and growth	0.002	0.997	0.000
M89.1 Epiphyseal arrest	0.002	0.997	0.000
S06.91 Intracranial injury, unspecified (with open intracranial wound)	0.002	0.997	0.000
I86.4 Gastric varices	0.002	0.997	0.001
J32.1 Chronic frontal sinusitis	0.003	0.997	0.000
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)	0.003	0.997	0.000
D48.1 Connective and other soft tissue	0.003	0.997	0.000
Z74.1 Need for assistance with personal care	0.002	0.997	0.000
S06.41 Epidural haemorrhage (with open intracranial wound)	0.002	0.997	0.000
A08.3 Other viral enteritis	0.002	0.997	0.000
O46 Antepartum haemorrhage, not elsewhere classified	0.000	0.997	0.002
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.000	0.997	0.002
S09 Other and unspecified injuries of head	0.002	0.997	0.000
Z74.3 Need for continuous supervision	0.002	0.998	0.000
S06.90 Intracranial injury, unspecified (without open intracranial wound)	0.002	0.998	0.000
M89.0 Algoneurodystrophy	0.002	0.998	0.000
M89.94 Disorder of bone, unspecified (Hand)	0.002	0.998	0.000
H66.9 Otitis media, unspecified	0.000	0.998	0.002
G37 Other demyelinating diseases of central nervous system	0.002	0.998	0.000
C77.0 Lymph nodes of head, face and neck	0.002	0.998	0.000
U80.8 Agent resistant to other penicillin-related antibiotic	0.000	0.998	0.002
A08.5 Other specified intestinal infections	0.002	0.998	0.000
A08.2 Adenoviral enteritis	0.002	0.998	0.000
A08.0 Rotaviral enteritis	0.002	0.998	0.000
M89.3 Hypertrophy of bone	0.002	0.998	0.000
M90.7 Fracture of bone in neoplastic disease	0.002	0.998	0.000
C02.1 Border of tongue	0.002	0.998	0.000
C18.4 Transverse colon	0.002	0.998	0.000
M90.78 Fracture of bone in neoplastic disease (Other)	0.002	0.998	0.000
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.002	0.998	0.000
J32.3 Chronic sphenoidal sinusitis	0.002	0.998	0.000
C18.3 Hepatic flexure	0.002	0.998	0.000
G36 Other acute disseminated demyelination	0.002	0.998	0.000
S06.40 Epidural haemorrhage (without open intracranial wound)	0.002	0.998	0.000
I85.9 Oesophageal varices without bleeding	0.000	0.998	0.002
H35.3 Degeneration of macula and posterior pole	0.000	0.998	0.002
I98.2 Oesophageal varices in diseases classified elsewhere	0.000	0.998	0.002
Z03.5 Observation for other suspected cardiovascular diseases	0.002	0.998	0.000
J93 Pneumothorax	0.000	0.998	0.002
S22.20 Fracture of sternum (closed)	0.002	0.998	0.000
M89.5 Osteolysis	0.002	0.998	0.000
S42.00 Fracture of clavicle (closed)	0.000	0.998	0.002
S06.31 Focal brain injury (with open intracranial wound)	0.002	0.998	0.000
O41.0 Oligohydramnios	0.000	0.998	0.002
R34 Anuria and oliguria	0.002	0.998	0.000
A08.1 Acute gastro-enteropathy due to Norwalk agent	0.002	0.998	0.000
O43.1 Malformation of placenta	0.000	0.998	0.002
R30.9 Painful micturition, unspecified	0.002	0.998	0.001
M89.19 Epiphyseal arrest (Site unspecified)	0.002	0.998	0.000
M89.18 Epiphyseal arrest (Other)	0.002	0.998	0.000
M89.17 Epiphyseal arrest (Ankle and foot)	0.002	0.998	0.000
M89.16 Epiphyseal arrest (Lower leg)	0.002	0.998	0.000
M89.15 Epiphyseal arrest (Pelvic region and thigh)	0.002	0.998	0.000
M89.14 Epiphyseal arrest (Hand)	0.002	0.998	0.000
M89.13 Epiphyseal arrest (Forearm)	0.002	0.998	0.000
M89.12 Epiphyseal arrest (Upper arm)	0.002	0.998	0.000
M89.11 Epiphyseal arrest (Shoulder region)	0.002	0.998	0.000
M89.10 Epiphyseal arrest (Multiple sites)	0.002	0.998	0.000
M89.29 Other disorders of bone development and growth (Site unspecified)	0.002	0.998	0.000
M89.28 Other disorders of bone development and growth (Other)	0.002	0.998	0.000
M89.27 Other disorders of bone development and growth (Ankle and foot)	0.002	0.998	0.000
M89.26 Other disorders of bone development and growth (Lower leg)	0.002	0.998	0.000
M89.25 Other disorders of bone development and growth (Pelvic region and thigh)	0.002	0.998	0.000
M89.24 Other disorders of bone development and growth (Hand)	0.002	0.998	0.000
M89.23 Other disorders of bone development and growth (Forearm)	0.002	0.998	0.000
M89.22 Other disorders of bone development and growth (Upper arm)	0.002	0.998	0.000
M89.21 Other disorders of bone development and growth (Shoulder region)	0.002	0.998	0.000
M89.20 Other disorders of bone development and growth (Multiple sites)	0.002	0.998	0.000
M89.49 Other hypertrophic osteoarthropathy (Site unspecified)	0.002	0.998	0.000
M89.48 Other hypertrophic osteoarthropathy (Other)	0.002	0.998	0.000
M89.47 Other hypertrophic osteoarthropathy (Ankle and foot)	0.002	0.998	0.000
M89.46 Other hypertrophic osteoarthropathy (Lower leg)	0.002	0.998	0.000
M89.45 Other hypertrophic osteoarthropathy (Pelvic region and thigh)	0.002	0.998	0.000
M89.44 Other hypertrophic osteoarthropathy (Hand)	0.002	0.998	0.000
M89.43 Other hypertrophic osteoarthropathy (Forearm)	0.002	0.998	0.000
M89.42 Other hypertrophic osteoarthropathy (Upper arm)	0.002	0.998	0.000
M89.41 Other hypertrophic osteoarthropathy (Shoulder region)	0.002	0.998	0.000
M89.40 Other hypertrophic osteoarthropathy (Multiple sites)	0.002	0.998	0.000
M89.69 Osteopathy after poliomyelitis (Site unspecified)	0.002	0.998	0.000
M89.68 Osteopathy after poliomyelitis (Other)	0.002	0.998	0.000
M89.67 Osteopathy after poliomyelitis (Ankle and foot)	0.002	0.998	0.000
M89.66 Osteopathy after poliomyelitis (Lower leg)	0.002	0.998	0.000
M89.65 Osteopathy after poliomyelitis (Pelvic region and thigh)	0.002	0.998	0.000
M89.64 Osteopathy after poliomyelitis (Hand)	0.002	0.998	0.000
M89.63 Osteopathy after poliomyelitis (Forearm)	0.002	0.998	0.000
M89.62 Osteopathy after poliomyelitis (Upper arm)	0.002	0.998	0.000
M89.61 Osteopathy after poliomyelitis (Shoulder region)	0.002	0.998	0.000
M89.60 Osteopathy after poliomyelitis (Multiple sites)	0.002	0.998	0.000
R03 Abnormal blood-pressure reading, without diagnosis	0.002	0.998	0.000
M70.65 Trochanteric bursitis-Pelvic/Thigh	0.000	0.998	0.002
O47.0 False labour before 37 completed weeks of gestation	0.000	0.998	0.002
S09.8 Other specified injuries of head	0.002	0.998	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.002	0.998	0.000
J32.2 Chronic ethmoidal sinusitis	0.002	0.998	0.000
J93.1 Other spontaneous pneumothorax	0.000	0.998	0.002
K04.6 Periapical abscess with sinus	0.002	0.998	0.000
U80.0 Penicillin resistant agent	0.000	0.998	0.002
S09.0 Injury of blood vessels of head, not elsewhere classified	0.002	0.998	0.000
G37.8 Other specified demyelinating diseases of central nervous system	0.002	0.998	0.000
I87.1 Compression of vein	0.002	0.998	0.001
O46.0 Antepartum haemorrhage with coagulation defect	0.000	0.998	0.002
I87.8 Other specified disorders of veins	0.002	0.998	0.000
S09.7 Multiple injuries of head	0.002	0.998	0.000
S09.2 Traumatic rupture of ear drum	0.002	0.998	0.000
S09.1 Injury of muscle and tendon of head	0.002	0.998	0.000
M11.26 Other chondrocalcinosis (Lower leg)	0.000	0.998	0.002
M89.09 Algoneurodystrophy (Site unspecified)	0.002	0.998	0.000
M89.08 Algoneurodystrophy (Other)	0.002	0.998	0.000
M89.07 Algoneurodystrophy (Ankle and foot)	0.002	0.998	0.000
M89.05 Algoneurodystrophy (Pelvic region and thigh)	0.002	0.998	0.000
M89.04 Algoneurodystrophy (Hand)	0.002	0.998	0.000
M89.02 Algoneurodystrophy (Upper arm)	0.002	0.998	0.000
M89.01 Algoneurodystrophy (Shoulder region)	0.002	0.998	0.000
M89.00 Algoneurodystrophy (Multiple sites)	0.002	0.998	0.000
J30.1 Allergic rhinitis due to pollen	0.002	0.998	0.000
G37.5 Concentric sclerosis [Balo]	0.002	0.998	0.000
G37.4 Subacute necrotising myelitis	0.002	0.998	0.000
G37.2 Central pontine myelinolysis	0.002	0.998	0.000
G37.1 Central demyelination of corpus callosum	0.002	0.998	0.000
G37.0 Diffuse sclerosis	0.002	0.998	0.000
G82.2 Paraplegia, unspecified	0.002	0.998	0.000
M47.12 Other spondylosis with myelopathy (Cervical region)	0.000	0.998	0.002
M89.39 Hypertrophy of bone (Site unspecified)	0.002	0.998	0.000
M89.38 Hypertrophy of bone (Other)	0.002	0.998	0.000
M89.36 Hypertrophy of bone (Lower leg)	0.002	0.998	0.000
M89.35 Hypertrophy of bone (Pelvic region and thigh)	0.002	0.998	0.000
M89.34 Hypertrophy of bone (Hand)	0.002	0.998	0.000
M89.33 Hypertrophy of bone (Forearm)	0.002	0.998	0.000
M89.32 Hypertrophy of bone (Upper arm)	0.002	0.998	0.000
M89.31 Hypertrophy of bone (Shoulder region)	0.002	0.998	0.000
M89.30 Hypertrophy of bone (Multiple sites)	0.002	0.998	0.000
M90.79 Fracture of bone in neoplastic disease (Site unspecified)	0.002	0.998	0.000
M90.77 Fracture of bone in neoplastic disease (Ankle and foot)	0.002	0.998	0.000
M90.76 Fracture of bone in neoplastic disease (Lower leg)	0.002	0.998	0.000
M90.74 Fracture of bone in neoplastic disease (Hand)	0.002	0.998	0.000
M90.73 Fracture of bone in neoplastic disease (Forearm)	0.002	0.998	0.000
M90.71 Fracture of bone in neoplastic disease (Shoulder region)	0.002	0.998	0.000
M90.70 Fracture of bone in neoplastic disease (Multiple sites)	0.002	0.998	0.000
G36.9 Acute disseminated demyelination, unspecified	0.002	0.998	0.000
G36.8 Other specified acute disseminated demyelination	0.002	0.998	0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]	0.002	0.998	0.000
G36.0 Neuromyelitis optica [Devic]	0.002	0.998	0.000
O41.8 Other specified disorders of amniotic fluid and membranes	0.000	0.998	0.002
I83 Varicose veins of lower extremities	0.002	0.998	0.000
M90.72 Fracture of bone in neoplastic disease (Upper arm)	0.002	0.998	0.000
C18.6 Descending colon	0.002	0.998	0.000
Q54.0 Hypospadias, balanic	0.002	0.998	0.000
O41 Other disorders of amniotic fluid and membranes	0.000	0.998	0.002
M89.06 Algoneurodystrophy (Lower leg)	0.002	0.998	0.000
M89.03 Algoneurodystrophy (Forearm)	0.002	0.998	0.000
M90 Osteopathies in diseases classified elsewhere	0.002	0.998	0.000
O46.8 Other antepartum haemorrhage	0.000	0.998	0.002
M89.59 Osteolysis (Site unspecified)	0.002	0.998	0.000
M89.58 Osteolysis (Other)	0.002	0.998	0.000
M89.57 Osteolysis (Ankle and foot)	0.002	0.998	0.000
M89.56 Osteolysis (Lower leg)	0.002	0.998	0.000
M89.54 Osteolysis (Hand)	0.002	0.998	0.000
M89.53 Osteolysis (Forearm)	0.002	0.998	0.000
M89.52 Osteolysis (Upper arm)	0.002	0.998	0.000
M89.51 Osteolysis (Shoulder region)	0.002	0.998	0.000
M89.50 Osteolysis (Multiple sites)	0.002	0.998	0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.002	0.998	0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.002	0.998	0.000
E21.0 Primary hyperparathyroidism	0.000	0.998	0.002
O42 Premature rupture of membranes	0.000	0.998	0.002
G95.9 Disease of spinal cord, unspecified	0.002	0.998	0.000
C18.2 Ascending colon	0.002	0.998	0.000
M89.37 Hypertrophy of bone (Ankle and foot)	0.001	0.998	0.000
J93.0 Spontaneous tension pneumothorax	0.000	0.998	0.002
K60.1 Chronic anal fissure	0.002	0.998	0.000
S63.6 Sprain and strain of finger(s)	0.002	0.998	0.000
H81.0 Meniere's disease	0.000	0.998	0.002
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm	0.002	0.998	0.000
O41.9 Disorder of amniotic fluid and membranes, unspecified	0.000	0.998	0.002
O41.1 Infection of amniotic sac and membranes	0.000	0.998	0.002
M90.8 Osteopathy in other diseases classified elsewhere	0.001	0.998	0.000
M90.6 Osteitis deformans in neoplastic disease	0.001	0.998	0.000
M90.5 Osteonecrosis in other diseases classified elsewhere	0.001	0.998	0.000
M90.4 Osteonecrosis due to heamoglobinopathy	0.001	0.998	0.000
M90.3 Osteonecrosis in caisson disease	0.001	0.998	0.000
M90.2 Osteopathy in other infectious diseases classified elsewhere	0.001	0.998	0.000
M90.1 Periostitis in other infectious diseases classified elsewhere	0.001	0.998	0.000
M90.0 Tuberculosis of bone	0.001	0.998	0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations