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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2301601
log Bayes Factor = 7.06119
Chromosome 16   position 23,366,528  (GRCh37) Explore rs2301601 on Ensembl!
Variant rs2301601 is part of Cluster X0061

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.999 0.001 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.999 0.001 0.000
Chapter VI Diseases of the nervous system
0.999 0.001 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.998 0.002 0.000
Chapter XX External causes of morbidity and mortality
0.998 0.002 0.000
G40-G47 Episodic and paroxysmal disorders
0.997 0.003 0.000
G40 Epilepsy
0.997 0.003 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.988 0.012 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.986 0.014 0.000
D60-D64 Aplastic and other anaemias
0.981 0.019 0.000
O26.8 Other specified pregnancy-related conditions
0.973 0.027 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.972 0.028 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.970 0.030 0.000
Chapter I Certain infectious and parasitic diseases
0.970 0.030 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.967 0.033 0.000
D63.0 Anaemia in neoplastic disease
0.961 0.039 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.957 0.043 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.952 0.048 0.000
W00-W19 Falls
0.942 0.058 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.937 0.063 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.932 0.068 0.000
G40.9 Epilepsy, unspecified
0.932 0.068 0.000
S00-S09 Injuries to the head
0.925 0.075 0.000
O23 Infections of genito-urinary tract in pregnancy
0.924 0.076 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.923 0.077 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.922 0.078 0.000
B95-B98 Bacterial, viral and other infectious agents
0.915 0.085 0.000
O20 Haemorrhage in early pregnancy
0.913 0.087 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.913 0.087 0.000
O16 Unspecified maternal hypertension
0.908 0.092 0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis
0.904 0.096 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.901 0.099 0.000
D62 Acute posthaemorrhagic anaemia
0.899 0.101 0.000
Y52 Agents primarily affecting the cardiovascular system
0.899 0.101 0.000
T14 Injury of unspecified body region
0.897 0.103 0.000
Q80-Q89 Other congenital malformations
0.892 0.108 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.892 0.108 0.000
O20.9 Haemorrhage in early pregnancy, unspecified
0.891 0.109 0.000
A30-A49 Other bacterial diseases
0.889 0.111 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.887 0.113 0.000
W50-W64 Exposure to animate mechanical forces
0.887 0.113 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.884 0.116 0.000
Chapter II Neoplasms
0.883 0.117 0.000
Q60-Q64 Congenital malformations of the urinary system
0.881 0.119 0.000
Q00-Q07 Congenital malformations of the nervous system
0.878 0.122 0.000
Y40 Systemic antibiotics
0.873 0.127 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.872 0.128 0.000
W19 Unspecified fall
0.871 0.129 0.000
O23.4 Unspecified infection of urinary tract in pregnancy
0.869 0.131 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.863 0.137 0.000
S50-S59 Injuries to the elbow and forearm
0.860 0.140 0.000
X20-X29 Contact with venomous animals and plants
0.854 0.146 0.000
S00 Superficial injury of head
0.853 0.147 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.851 0.149 0.000
O24 Diabetes mellitus in pregnancy
0.851 0.149 0.000
M20-M25 Other joint disorders
0.850 0.150 0.000
O26.9 Pregnancy-related condition, unspecified
0.850 0.150 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.849 0.151 0.000
B25-B34 Other viral diseases
0.848 0.152 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.848 0.152 0.000
T14.0 Superficial injury of unspecified body region
0.848 0.152 0.000
M25 Other joint disorders, not elsewhere classified
0.846 0.154 0.000
G70-G73 Diseases of myoneural junction and muscle
0.846 0.154 0.000
M25.5 Pain in joint
0.845 0.155 0.000
D61 Other aplastic anaemias
0.844 0.156 0.000
G83 Other paralytic syndromes
0.843 0.157 0.000
M65-M68 Disorders of synovium and tendon
0.842 0.158 0.000
G30-G32 Other degenerative diseases of the nervous system
0.842 0.158 0.000
D55-D59 Haemolytic anaemias
0.839 0.161 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.838 0.162 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.835 0.165 0.000
S32 Fracture of lumbar spine and pelvis
0.833 0.167 0.000
D80-D89 Certain disorders involving the immune mechanism
0.831 0.169 0.000
S40-S49 Injuries to the shoulder and upper arm
0.825 0.175 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.822 0.178 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.819 0.181 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.816 0.184 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.813 0.187 0.000
M25.57 Pain in joint (Ankle and foot)
0.811 0.189 0.000
S80-S89 Injuries to the knee and lower leg
0.811 0.189 0.000
T66-T78 Other and unspecified effects of external causes
0.808 0.192 0.000
G20-G26 Extrapyramidal and movement disorders
0.807 0.193 0.000
S70-S79 Injuries to the hip and thigh
0.805 0.195 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.803 0.197 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.802 0.198 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.800 0.200 0.000
V80-V89 Other land transport accidents
0.800 0.200 0.000
V20-V29 Motorcycle rider injured in transport accident
0.799 0.201 0.000
W20-W49 Exposure to inanimate mechanical forces
0.798 0.202 0.000
S06 Intracranial injury
0.798 0.202 0.000
W55 Bitten or struck by other mammals
0.795 0.205 0.000
W19.4 Street and highway
0.793 0.207 0.000
G44 Other headache syndromes
0.793 0.207 0.000
Q82 Other congenital malformations of skin
0.791 0.209 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.787 0.213 0.000
A41 Other septicaemia
0.784 0.216 0.000
V98-V99 Other and unspecified transport accidents
0.783 0.217 0.000
S00.9 Superficial injury of head, part unspecified
0.782 0.218 0.000
M45-M49 Spondylopathies
0.781 0.218 0.000
X10-X19 Contact with heat and hot substances
0.781 0.219 0.000
T00-T07 Injuries involving multiple body regions
0.781 0.219 0.000
T23 Burn and corrosion of wrist and hand
0.780 0.220 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.778 0.222 0.000
M31 Other necrotising vasculopathies
0.777 0.223 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.776 0.224 0.000
W07 Fall involving chair
0.775 0.225 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.773 0.227 0.000
G41 Status epilepticus
0.771 0.229 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.770 0.230 0.000
Q61 Cystic kidney disease
0.770 0.230 0.000
M67 Other disorders of synovium and tendon
0.769 0.231 0.000
Y40.9 Systemic antibiotic, unspecified
0.768 0.232 0.000
S00.0 Superficial injury of scalp
0.768 0.232 0.000
D47.3 Essential (haemorrhagic) thrombocythaemia
0.763 0.237 0.000
O40 Polyhydramnios
0.763 0.237 0.000
G40.5 Special epileptic syndromes
0.763 0.237 0.000
O85-O92 Complications predominantly related to the puerperium
0.762 0.237 0.000
W19.2 School, other institution and public administrative area
0.762 0.238 0.000
M66 Spontaneous rupture of synovium and tendon
0.760 0.240 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.760 0.240 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.760 0.240 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.759 0.241 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.757 0.243 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.755 0.244 0.000
T09 Other injuries of spine and trunk, level unspecified
0.755 0.245 0.000
Chapter V Mental and behavioural disorders
0.755 0.245 0.000
Q07 Other congenital malformations of nervous system
0.754 0.246 0.000
B99-B99 Other infectious diseases
0.753 0.247 0.000
G82 Paraplegia and tetraplegia
0.752 0.248 0.000
O21 Excessive vomiting in pregnancy
0.752 0.248 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.752 0.248 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.751 0.248 0.000
X23 Contact with hornets, wasps and bees
0.751 0.249 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.750 0.250 0.000
T21 Burn and corrosion of trunk
0.749 0.251 0.000
D46 Myelodysplastic syndromes
0.748 0.252 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.748 0.252 0.000
M60-M63 Disorders of muscles
0.748 0.252 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.747 0.253 0.000
W00 Fall on same level involving ice and snow
0.746 0.254 0.000
B34 Viral infection of unspecified site
0.746 0.254 0.000
A40 Streptococcal septicaemia
0.745 0.255 0.000
S31 Open wound of abdomen, lower back and pelvis
0.744 0.256 0.000
Q76 Congenital malformations of spine and bony thorax
0.743 0.257 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.743 0.257 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.742 0.258 0.000
A41.9 Septicaemia, unspecified
0.741 0.259 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.741 0.259 0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest
0.741 0.259 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.741 0.259 0.000
Q50-Q56 Congenital malformations of genital organs
0.738 0.262 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.738 0.262 0.000
V40-V49 Car occupant injured in transport accident
0.737 0.263 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.736 0.264 0.000
D86 Sarcoidosis
0.736 0.264 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.734 0.265 0.000
C34 Malignant neoplasm of bronchus and lung
0.734 0.266 0.000
G72 Other myopathies
0.733 0.267 0.000
D47.4 Osteomyelofibrosis
0.733 0.267 0.000
G25 Other extrapyramidal and movement disorders
0.732 0.268 0.000
A80-A89 Viral infections of the central nervous system
0.732 0.268 0.000
O28 Abnormal findings on antenatal screening of mother
0.730 0.270 0.000
O41 Other disorders of amniotic fluid and membranes
0.730 0.270 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.729 0.271 0.000
D58 Other hereditary haemolytic anaemias
0.729 0.271 0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified
0.728 0.272 0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems
0.726 0.274 0.000
S42 Fracture of shoulder and upper arm
0.726 0.274 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.726 0.274 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.725 0.275 0.000
M86-M90 Other osteopathies
0.725 0.275 0.000
G40.8 Other epilepsy
0.725 0.275 0.000
Y43 Primarily systemic agents
0.725 0.275 0.000
D47.1 Chronic myeloproliferative disease
0.724 0.275 0.000
T11 Other injuries of upper limb, level unspecified
0.722 0.278 0.000
Q28 Other congenital malformations of circulatory system
0.721 0.279 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.719 0.281 0.000
S36 Injury of intra-abdominal organs
0.718 0.282 0.000
M25.56 Pain in joint (Lower leg)
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
Q82.5 Congenital nonneoplastic naevus
0.716 0.284 0.000
A39 Meningococcal infection
0.716 0.284 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.716 0.284 0.000
O29 Complications of anaesthesia during pregnancy
0.716 0.284 0.000
O22 Venous complications in pregnancy
0.716 0.284 0.000
O25 Malnutrition in pregnancy
0.716 0.284 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.716 0.284 0.000
Q61.3 Polycystic kidney, unspecified
0.716 0.284 0.000
Y40.3 Macrolides
0.716 0.284 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.716 0.284 0.000
Q35-Q37 Cleft lip and cleft palate
0.716 0.284 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.716 0.284 0.000
Y35-Y36 Legal intervention and operations of war
0.715 0.285 0.000
Y10-Y34 Event of undetermined intent
0.715 0.285 0.000
X85-X99 Assault
0.715 0.285 0.000
X30-X39 Exposure to forces of nature
0.715 0.285 0.000
X00-X09 Exposure to smoke, fire and flames
0.715 0.285 0.000
W75-W84 Other accidental threats to breathing
0.715 0.285 0.000
W65-W74 Accidental drowning and submersion
0.715 0.285 0.000
V95-V97 Air and space transport accidents
0.715 0.285 0.000
V90-V94 Water transport accidents
0.715 0.285 0.000
V70-V79 Bus occupant injured in transport accident
0.715 0.285 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.715 0.285 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.715 0.285 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.715 0.285 0.000
V01-V09 Pedestrian injured in transport accident
0.715 0.285 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.715 0.285 0.000
V10-V19 Pedal cyclist injured in transport accident
0.715 0.285 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.715 0.285 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.715 0.285 0.000
G83.9 Paralytic syndrome, unspecified
0.715 0.285 0.000
S10-S19 Injuries to the neck
0.713 0.287 0.000
W18 Other fall on same level
0.713 0.287 0.000
S32.5 Fracture of pubis
0.712 0.288 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.712 0.288 0.000
W55.0 Home
0.711 0.289 0.000
A15-A19 Tuberculosis
0.710 0.290 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.710 0.290 0.000
W08 Fall involving other furniture
0.709 0.291 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.709 0.291 0.000
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium
0.709 0.291 0.000
O26.6 Liver disorders in pregnancy, childbirth and the puerperium
0.709 0.291 0.000
O26.5 Maternal hypotension syndrome
0.709 0.291 0.000
O26.4 Herpes gestationis
0.709 0.291 0.000
O26.3 Retained intra-uterine contraceptive device in pregnancy
0.709 0.291 0.000
O26.1 Low weight gain in pregnancy
0.709 0.291 0.000
O26.0 Excessive weight gain in pregnancy
0.709 0.291 0.000
S81 Open wound of lower leg
0.708 0.292 0.000
M25.59 Pain in joint (Site unspecified)
0.708 0.292 0.000
D61.9 Aplastic anaemia, unspecified
0.708 0.292 0.000
S00.5 Superficial injury of lip and oral cavity
0.706 0.294 0.000
Y00-Y09 Assault
0.705 0.295 0.000
T79-T79 Certain early complications of trauma
0.705 0.295 0.000
T20 Burn and corrosion of head and neck
0.705 0.295 0.000
Q05 Spina bifida
0.705 0.295 0.000
B27 Infectious mononucleosis
0.704 0.296 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.704 0.296 0.000
S90-S99 Injuries to the ankle and foot
0.704 0.296 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.704 0.296 0.000
O26.2 Pregnancy care of habitual aborter
0.703 0.297 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.703 0.297 0.000
W06 Fall involving bed
0.702 0.298 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.700 0.300 0.000
Q43 Other congenital malformations of intestine
0.699 0.301 0.000
O24.4 Diabetes mellitus arising in pregnancy
0.699 0.301 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.699 0.301 0.000
Y57 Other and unspecified drugs and medicaments
0.698 0.302 0.000
O32.8 Maternal care for other malpresentation of foetus
0.697 0.303 0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified
0.697 0.303 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.696 0.303 0.000
S37 Injury of urinary and pelvic organs
0.696 0.303 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.696 0.303 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.696 0.303 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.696 0.303 0.000
S50 Superficial injury of forearm
0.696 0.304 0.000
Y59 Other and unspecified vaccines and biological substances
0.695 0.304 0.000
Y58 Bacterial vaccines
0.695 0.304 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.695 0.304 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.695 0.304 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.695 0.304 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.695 0.305 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.695 0.305 0.000
A75-A79 Rickettsioses
0.695 0.305 0.000
A70-A74 Other diseases caused by chlamydiae
0.695 0.305 0.000
A65-A69 Other spirochaetal diseases
0.695 0.305 0.000
A20-A28 Certain zoonotic bacterial diseases
0.695 0.305 0.000
G71 Primary disorders of muscles
0.695 0.305 0.000
Q66 Congenital deformities of feet
0.694 0.306 0.000
D63.1 Anaemia in other chronic diseases classified elsewhere
0.693 0.306 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.693 0.306 0.000
T14.1 Open wound of unspecified body region
0.692 0.308 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.692 0.308 0.000
C15-C26 Malignant neoplasms of digestive organs
0.692 0.308 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.691 0.309 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.691 0.309 0.000
W60 Contact with plant thorns and spines and sharp leaves
0.690 0.310 0.000
D00-D09 In situ neoplasms
0.690 0.310 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.687 0.313 0.000
Y40.8 Other systemic antibiotics
0.685 0.315 0.000
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified
0.685 0.315 0.000
Q64 Other congenital malformations of urinary system
0.685 0.315 0.000
Y48 Anaesthetics and therapeutic gases
0.684 0.315 0.000
O32.1 Maternal care for breech presentation
0.684 0.316 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.683 0.317 0.000
C34.9 Bronchus or lung, unspecified
0.683 0.317 0.000
G81 Hemiplegia
0.682 0.318 0.000
T13 Other injuries of lower limb, level unspecified
0.682 0.318 0.000
T12.X1 Fracture of lower limb, level unspecified (open)
0.682 0.318 0.000
T12.X0 Fracture of lower limb, level unspecified (closed)
0.682 0.318 0.000
T12 Fracture of lower limb, level unspecified
0.682 0.318 0.000
T10.X1 Fracture of upper limb, level unspecified (open)
0.682 0.318 0.000
T10.X0 Fracture of upper limb, level unspecified (closed)
0.682 0.318 0.000
T10 Fracture of upper limb, level unspecified
0.682 0.318 0.000
T08.X1 Fracture of spine, level unspecified (open)
0.682 0.318 0.000
T08.X0 Fracture of spine, level unspecified (closed)
0.682 0.318 0.000
T08 Fracture of spine, level unspecified
0.682 0.318 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.682 0.318 0.000
G83.1 Monoplegia of lower limb
0.682 0.318 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.681 0.319 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.680 0.319 0.000
X60-X84 Intentional self-harm
0.680 0.320 0.000
M47 Spondylosis
0.680 0.320 0.000
S02 Fracture of skull and facial bones
0.680 0.320 0.000
S06.9 Intracranial injury, unspecified
0.678 0.322 0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics
0.678 0.322 0.000
O23.9 Other and unspecified genito-urinary tract infection in pregnancy
0.677 0.322 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.677 0.323 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.676 0.324 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.675 0.324 0.000
W14 Fall from tree
0.675 0.324 0.000
W12 Fall on and from scaffolding
0.675 0.324 0.000
W11 Fall on and from ladder
0.675 0.324 0.000
W09 Fall involving playground equipment
0.675 0.324 0.000
W05 Fall involving wheelchair
0.675 0.324 0.000
W04 Fall while being carried or supported by other persons
0.675 0.324 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.675 0.324 0.000
W15 Fall from cliff
0.674 0.326 0.000
D37.7 Other digestive organs
0.674 0.326 0.000
B50-B64 Protozoal diseases
0.673 0.326 0.000
Q23 Congenital malformations of aortic and mitral valves
0.673 0.327 0.000
D61.0 Constitutional aplastic anaemia
0.672 0.328 0.000
O15 Eclampsia
0.672 0.328 0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria
0.672 0.328 0.000
W19.6 Industrial and construction area
0.671 0.328 0.000
X23.9 Unspecified place
0.671 0.329 0.000
Q21 Congenital malformations of cardiac septa
0.669 0.331 0.000
G83.8 Other specified paralytic syndromes
0.669 0.331 0.000
O41.8 Other specified disorders of amniotic fluid and membranes
0.669 0.331 0.000
M25.3 Other instability of joint
0.669 0.331 0.000
S39.8 Other specified injuries of abdomen, lower back and pelvis
0.668 0.332 0.000
S39.7 Other multiple injuries of abdomen, lower back and pelvis
0.668 0.332 0.000
S39.6 Injury of intra-abdominal organ(s) with pelvic organ(s)
0.668 0.332 0.000
S39.0 Injury of muscle and tendon of abdomen, lower back and pelvis
0.668 0.332 0.000
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified
0.667 0.333 0.000
A49 Bacterial infection of unspecified site
0.667 0.333 0.000
G44.8 Other specified headache syndromes
0.667 0.333 0.000
Q89 Other congenital malformations, not elsewhere classified
0.667 0.333 0.000
M25.9 Joint disorder, unspecified
0.666 0.334 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.666 0.334 0.000
Q07.0 Arnold-Chiari syndrome
0.665 0.335 0.000
M70-M79 Other soft tissue disorders
0.664 0.336 0.000
W19.1 Residential institution
0.664 0.336 0.000
M46 Other inflammatory spondylopathies
0.663 0.337 0.000
S20-S29 Injuries to the thorax
0.663 0.337 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.663 0.337 0.000
S08 Traumatic amputation of part of head
0.663 0.337 0.000
S07 Crushing injury of head
0.663 0.337 0.000
S04 Injury of cranial nerves
0.663 0.337 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.663 0.337 0.000
D86.9 Sarcoidosis, unspecified
0.663 0.337 0.000
O23.3 Infections of other parts of urinary tract in pregnancy
0.663 0.337 0.000
O23.2 Infections of urethra in pregnancy
0.663 0.337 0.000
O23.1 Infections of bladder in pregnancy
0.663 0.337 0.000
O23.0 Infections of kidney in pregnancy
0.663 0.337 0.000
T25 Burn and corrosion of ankle and foot
0.661 0.338 0.000
S80 Superficial injury of lower leg
0.661 0.339 0.000
S32.0 Fracture of lumbar vertebra
0.661 0.339 0.000
M31.0 Hypersensitivity angiitis
0.661 0.339 0.000
S81.8 Open wound of other parts of lower leg
0.660 0.340 0.000
M66.2 Spontaneous rupture of extensor tendons
0.660 0.340 0.000
D46.9 Myelodysplastic syndrome, unspecified
0.659 0.340 0.000
M33 Dermatopolymyositis
0.659 0.341 0.000
O23.5 Infections of the genital tract in pregnancy
0.658 0.341 0.000
Q39 Congenital malformations of oesophagus
0.658 0.342 0.000
T90 Sequelae of injuries of head
0.658 0.342 0.000
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified
0.658 0.342 0.000
W51 Striking against or bumped into by another person
0.658 0.342 0.000
S56 Injury of muscle and tendon at forearm level
0.657 0.343 0.000
M67.8 Other specified disorders of synovium and tendon
0.657 0.343 0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)
0.657 0.343 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.656 0.343 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.656 0.344 0.000
V23 Motorcycle rider injured in collision with car, pick-up truck or van
0.656 0.344 0.000
Y44 Agents primarily affecting blood constituents
0.655 0.345 0.000
S52 Fracture of forearm
0.655 0.345 0.000
O24.0 Pre-existing diabetes mellitus, insulin-dependent
0.654 0.345 0.000
C43 Malignant melanoma of skin
0.653 0.347 0.000
O47 False labour
0.653 0.347 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.652 0.347 0.000
W17 Other fall from one level to another
0.652 0.348 0.000
S71 Open wound of hip and thigh
0.652 0.348 0.000
Y40.1 Cefalosporins and other -lactam antibiotics
0.651 0.349 0.000
M30 Polyarteritis nodosa and related conditions
0.650 0.350 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.649 0.351 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.649 0.351 0.000
S01 Open wound of head
0.649 0.351 0.000
S06.5 Traumatic subdural haemorrhage
0.648 0.352 0.000
M62 Other disorders of muscle
0.648 0.352 0.000
F41 Other anxiety disorders
0.648 0.352 0.000
M45 Ankylosing spondylitis
0.648 0.352 0.000
T91 Sequelae of injuries of neck and trunk
0.647 0.353 0.000
W22 Striking against or struck by other objects
0.647 0.353 0.000
Q78 Other osteochondrodysplasias
0.646 0.354 0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine
0.646 0.354 0.000
Q75 Other congenital malformations of skull and face bones
0.646 0.354 0.000
Q74 Other congenital malformations of limb(s)
0.646 0.354 0.000
Q73 Reduction defects of unspecified limb
0.646 0.354 0.000
Q72 Reduction defects of lower limb
0.646 0.354 0.000
Q71 Reduction defects of upper limb
0.646 0.354 0.000
Q70 Syndactyly
0.646 0.354 0.000
Q69 Polydactyly
0.646 0.354 0.000
Q68 Other congenital musculoskeletal deformities
0.646 0.354 0.000
O24.9 Diabetes mellitus in pregnancy, unspecified
0.646 0.354 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.646 0.354 0.000
M86 Osteomyelitis
0.645 0.354 0.000
C04 Malignant neoplasm of floor of mouth
0.645 0.355 0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system
0.644 0.356 0.000
Y52.8 Antivaricose drugs, including sclerosing agents
0.644 0.356 0.000
Y52.7 Peripheral vasodilators
0.644 0.356 0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.644 0.356 0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action
0.644 0.356 0.000
B15-B19 Viral hepatitis
0.644 0.356 0.000
T14.2 Fracture of unspecified body region
0.643 0.357 0.000
T14.9 Injury, unspecified
0.643 0.357 0.000
T14.8 Other injuries of unspecified body region
0.643 0.357 0.000
T14.7 Crushing injury and traumatic amputation of unspecified body region
0.643 0.357 0.000
T14.6 Injury of tendons and muscles of unspecified body region
0.643 0.357 0.000
T14.5 Injury of blood vessel(s) of unspecified body region
0.643 0.357 0.000
T14.4 Injury of nerve(s) of unspecified body region
0.643 0.357 0.000
T14.3 Dislocation, sprain and strain of unspecified body region
0.643 0.357 0.000
G25.8 Other specified extrapyramidal and movement disorders
0.643 0.357 0.000
S70 Superficial injury of hip and thigh
0.642 0.358 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.641 0.359 0.000
T23.2 Burn of second degree of wrist and hand
0.640 0.360 0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified
0.640 0.360 0.000
Q84 Other congenital malformations of integument
0.640 0.360 0.000
Q83 Congenital malformations of breast
0.640 0.360 0.000
Q81 Epidermolysis bullosa
0.640 0.360 0.000
Q80 Congenital ichthyosis
0.640 0.360 0.000
S06.3 Focal brain injury
0.640 0.360 0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.638 0.361 0.000
G30 Alzheimer's disease
0.638 0.361 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.638 0.362 0.000
M00-M03 Infectious arthropathies
0.638 0.362 0.000
S00.4 Superficial injury of ear
0.638 0.362 0.000
A44 Bartonellosis
0.637 0.363 0.000
A43 Nocardiosis
0.637 0.363 0.000
A42 Actinomycosis
0.637 0.363 0.000
A37 Whooping cough
0.637 0.363 0.000
A36 Diphtheria
0.637 0.363 0.000
A32 Listeriosis
0.637 0.363 0.000
A31 Infection due to other mycobacteria
0.637 0.363 0.000
A30 Leprosy [Hansen's disease]
0.637 0.363 0.000
A38 Scarlet fever
0.637 0.363 0.000
A35 Other tetanus
0.637 0.363 0.000
A34 Obstetrical tetanus
0.637 0.363 0.000
A33 Tetanus neonatorum
0.637 0.363 0.000
G83.2 Monoplegia of upper limb
0.637 0.363 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.636 0.364 0.000
W64 Exposure to other and unspecified animate mechanical forces
0.636 0.364 0.000
W59 Bitten or crushed by other reptiles
0.636 0.364 0.000
W58 Bitten or struck by crocodile or alligator
0.636 0.364 0.000
W56 Contact with marine animal
0.636 0.364 0.000
W54 Bitten or struck by dog
0.636 0.364 0.000
W53 Bitten by rat
0.636 0.364 0.000
W52 Crushed, pushed and stepped on by crowd or human stampede
0.636 0.364 0.000
B65-B83 Helminthiases
0.635 0.364 0.000
T31 Burns classified according to extent of body surface involved
0.635 0.364 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.633 0.366 0.000
T66 Unspecified effects of radiation
0.633 0.367 0.000
S32.1 Fracture of sacrum
0.633 0.367 0.000
Q25 Congenital malformations of great arteries
0.632 0.368 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.632 0.368 0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.631 0.369 0.000
C34.3 Lower lobe, bronchus or lung
0.630 0.370 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.629 0.370 0.000
Q06 Other congenital malformations of spinal cord
0.629 0.371 0.000
Q04 Other congenital malformations of brain
0.629 0.371 0.000
Q03 Congenital hydrocephalus
0.629 0.371 0.000
Q01 Encephalocele
0.629 0.371 0.000
Q00 Anencephaly and similar malformations
0.629 0.371 0.000
Q02 Microcephaly
0.629 0.371 0.000
Q65 Congenital deformities of hip
0.629 0.371 0.000
V99 Unspecified transport accident
0.629 0.371 0.000
O32.9 Maternal care for malpresentation of foetus, unspecified
0.629 0.371 0.000
A40.9 Streptococcal septicaemia, unspecified
0.628 0.372 0.000
Chapter XXII Codes for special purposes
0.628 0.372 0.000
T68 Hypothermia
0.627 0.373 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.627 0.373 0.000
X50-X57 Overexertion, travel and privation
0.626 0.373 0.000
M67.4 Ganglion
0.626 0.374 0.000
M67.1 Other contracture of tendon (sheath)
0.626 0.374 0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis
0.626 0.374 0.000
Y40.7 Antifungal antibiotics, systemically used
0.626 0.374 0.000
Y40.6 Rifamycins
0.626 0.374 0.000
Y40.5 Aminoglycosides
0.626 0.374 0.000
Y40.4 Tetracyclines
0.626 0.374 0.000
Y40.2 Chloramphenicol group
0.626 0.374 0.000
X19 Contact with other and unspecified heat and hot substances
0.625 0.375 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.625 0.375 0.000
Q67.5 Congenital deformity of spine
0.625 0.375 0.000
S32.50 Fracture of pubis (closed)
0.625 0.375 0.000
M21 Other acquired deformities of limbs
0.625 0.375 0.000
W19.8 Other specified place
0.624 0.375 0.000
W19.5 Trade and service area
0.624 0.375 0.000
W19.0 Home
0.624 0.375 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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