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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2429722
log Bayes Factor = 43.8626
Chromosome 6   position 31,064,305  (GRCh37) Explore rs2429722 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
I25.1 Atherosclerotic heart disease
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.001 0.999
L40 Psoriasis
0.000 0.002 0.998
E78.0 Pure hypercholesterolaemia
0.000 0.002 0.998
E11 Non-insulin-dependent diabetes mellitus
0.000 0.002 0.998
M06.9 Rheumatoid arthritis, unspecified
0.000 0.003 0.997
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.003 0.997
I21 Acute myocardial infarction
0.000 0.003 0.997
E11.9 Without complications
0.000 0.006 0.994
L40.5 Arthropathic psoriasis
0.000 0.006 0.994
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.008 0.992
I21.9 Acute myocardial infarction, unspecified
0.000 0.011 0.989
E10.3 With ophthalmic complications
0.000 0.011 0.989
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.012 0.988
I20 Angina pectoris
0.000 0.026 0.974
I24 Other acute ischaemic heart diseases
0.000 0.029 0.971
E14 Unspecified diabetes mellitus
0.000 0.050 0.950
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.052 0.948
I20.9 Angina pectoris, unspecified
0.000 0.053 0.947
I25.2 Old myocardial infarction
0.000 0.054 0.946
J45.9 Asthma, unspecified
0.000 0.072 0.928
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.085 0.915
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.091 0.909
E70-E90 Metabolic disorders
0.000 0.093 0.906
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.093 0.907
I20.0 Unstable angina
0.000 0.099 0.901
I24.8 Other forms of acute ischaemic heart disease
0.000 0.101 0.899
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.109 0.891
I25.5 Ischaemic cardiomyopathy
0.000 0.109 0.891
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.112 0.888
E14.9 Without complications
0.000 0.119 0.881
E10.4 With neurological complications
0.000 0.122 0.878
K90 Intestinal malabsorption
0.000 0.128 0.872
E11.0 With coma
0.000 0.133 0.867
I22 Subsequent myocardial infarction
0.000 0.134 0.866
E78.2 Mixed hyperlipidaemia
0.000 0.135 0.865
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.139 0.861
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.143 0.857
L40-L45 Papulosquamous disorders
0.000 0.146 0.854
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.154 0.846
E10.2 With renal complications
0.000 0.167 0.833
M06 Other rheumatoid arthritis
0.000 0.167 0.833
L40.0 Psoriasis vulgaris
0.000 0.175 0.825
E13 Other specified diabetes mellitus
0.000 0.178 0.822
E14.3 With ophthalmic complications
0.000 0.182 0.818
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.187 0.813
L43 Lichen planus
0.000 0.187 0.813
K90.9 Intestinal malabsorption, unspecified
0.000 0.188 0.812
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.190 0.810
E10.1 With ketoacidosis
0.000 0.192 0.808
E11.1 With ketoacidosis
0.000 0.202 0.798
L43.9 Lichen planus, unspecified
0.000 0.216 0.784
E85 Amyloidosis
0.000 0.230 0.770
E11.6 With other specified complications
0.000 0.230 0.770
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.235 0.765
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.253 0.747
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.254 0.746
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.256 0.744
E11.4 With neurological complications
0.000 0.278 0.722
E10.8 With unspecified complications
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E10.6 With other specified complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
I23 Certain current complications following acute myocardial infarction
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
L40.8 Other psoriasis
0.000 0.284 0.715
L40.4 Guttate psoriasis
0.000 0.284 0.715
L40.3 Pustulosis palmaris et plantaris
0.000 0.284 0.715
L40.2 Acrodermatitis continua
0.000 0.284 0.715
L40.1 Generalised pustular psoriasis
0.000 0.284 0.715
E11.7 With multiple complications
0.000 0.285 0.715
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.285 0.715
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.285 0.715
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.285 0.715
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.286 0.714
E11.8 With unspecified complications
0.000 0.292 0.708
E74 Other disorders of carbohydrate metabolism
0.000 0.297 0.703
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.297 0.703
E13.9 Without complications
0.000 0.305 0.695
E11.2 With renal complications
0.000 0.305 0.695
E11.5 With peripheral circulatory complications
0.000 0.306 0.694
E10.5 With peripheral circulatory complications
0.000 0.306 0.694
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.308 0.692
E78.5 Hyperlipidaemia, unspecified
0.000 0.313 0.687
I25.3 Aneurysm of heart
0.000 0.314 0.686
E83 Disorders of mineral metabolism
0.467 0.316 0.217
E14.8 With unspecified complications
0.000 0.319 0.681
E14.7 With multiple complications
0.000 0.319 0.681
E14.6 With other specified complications
0.000 0.319 0.681
E14.5 With peripheral circulatory complications
0.000 0.319 0.681
E14.2 Withrenal complications
0.000 0.319 0.681
E14.1 With ketoacidosis
0.000 0.319 0.681
E14.0 With coma
0.000 0.319 0.681
E78.6 Lipoprotein deficiency
0.000 0.320 0.680
E78.3 Hyperchylomicronaemia
0.000 0.320 0.680
E78.8 Other disorders of lipoprotein metabolism
0.000 0.324 0.676
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.324 0.676
M06.0 Seronegative rheumatoid arthritis
0.000 0.338 0.662
E14.4 With neurological complications
0.000 0.338 0.661
E84 Cystic fibrosis
0.000 0.350 0.650
E79 Disorders of purine and pyrimidine metabolism
0.000 0.350 0.650
E77 Disorders of glycoprotein metabolism
0.000 0.350 0.650
E76 Disorders of glycosaminoglycan metabolism
0.000 0.350 0.650
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.350 0.650
E72 Other disorders of amino-acid metabolism
0.000 0.350 0.650
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.350 0.650
E70 Disorders of aromatic amino-acid metabolism
0.000 0.350 0.650
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.350 0.650
M06.3 Rheumatoid nodule
0.000 0.352 0.648
I20.1 Angina pectoris with documented spasm
0.000 0.356 0.644
M05-M14 Inflammatory polyarthropathies
0.000 0.357 0.643
E85.9 Amyloidosis, unspecified
0.000 0.360 0.640
E40-E46 Malnutrition
0.000 0.361 0.639
I24.1 Dressler's syndrome
0.000 0.369 0.630
E78.1 Pure hyperglyceridaemia
0.000 0.371 0.629
E78.4 Other hyperlipidaemia
0.000 0.373 0.626
K90.8 Other intestinal malabsorption
0.000 0.375 0.625
K90.3 Pancreatic steatorrhoea
0.000 0.375 0.625
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.375 0.625
K90.1 Tropical sprue
0.000 0.375 0.625
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.386 0.614
L44 Other papulosquamous disorders
0.000 0.387 0.612
L41 Parapsoriasis
0.000 0.387 0.612
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.387 0.612
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.389 0.611
L42 Pityriasis rosea
0.000 0.391 0.609
E85.4 Organ-limited amyloidosis
0.000 0.394 0.606
M06.8 Other specified rheumatoid arthritis
0.000 0.403 0.597
M06.2 Rheumatoid bursitis
0.000 0.403 0.597
M06.1 Adult-onset Still's disease
0.000 0.403 0.597
E13.8 With unspecified complications
0.000 0.410 0.590
E13.7 With multiple complications
0.000 0.410 0.590
E13.6 With other specified complications
0.000 0.410 0.590
E13.5 With peripheral circulatory complications
0.000 0.410 0.590
E13.4 With neurological complications
0.000 0.410 0.590
E13.3 With ophthalmic complications
0.000 0.410 0.590
E13.2 With renal complications
0.000 0.410 0.590
E13.1 With ketoacidosis
0.000 0.410 0.590
E13.0 With coma
0.000 0.410 0.590
E73 Lactose intolerance
0.001 0.411 0.589
E00-E07 Disorders of thyroid gland
0.000 0.417 0.583
L43.8 Other lichen planus
0.000 0.417 0.583
L43.3 Subacute (active) lichen planus
0.000 0.417 0.583
L43.2 Lichenoid drug reaction
0.000 0.417 0.583
L43.1 Bullous lichen planus
0.000 0.417 0.583
L43.0 Hypertrophic lichen planus
0.000 0.417 0.583
M06.4 Inflammatory polyarthropathy
0.000 0.424 0.576
E16 Other disorders of pancreatic internal secretion
0.000 0.426 0.574
M07 Psoriatic and enteropathic arthropathies
0.000 0.427 0.573
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.443 0.557
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.444 0.556
E85.8 Other amyloidosis
0.000 0.448 0.552
E85.3 Secondary systemic amyloidosis
0.000 0.448 0.552
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.448 0.552
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.448 0.552
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.448 0.552
E03 Other hypothyroidism
0.000 0.449 0.551
I25.4 Coronary artery aneurysm
0.000 0.449 0.550
E88 Other metabolic disorders
0.000 0.450 0.550
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.457 0.543
I21.4 Acute subendocardial myocardial infarction
0.000 0.458 0.542
E50-E64 Other nutritional deficiencies
0.000 0.458 0.542
M05 Seropositive rheumatoid arthritis
0.000 0.463 0.537
I22.8 Subsequent myocardial infarction of other sites
0.000 0.472 0.528
M07.3 Other psoriatic arthropathies
0.000 0.476 0.523
G35-G37 Demyelinating diseases of the central nervous system
0.518 0.482 0.000
M06.34 Rheumatoid nodule (Hand)
0.000 0.485 0.515
I23.8 Other current complications following acute myocardial infarction
0.000 0.486 0.514
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.486 0.514
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E03.9 Hypothyroidism, unspecified
0.000 0.486 0.514
E15 Nondiabetic hypoglycaemic coma
0.000 0.488 0.512
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.496 0.504
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.496 0.504
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.496 0.504
E74.2 Disorders of galactose metabolism
0.000 0.496 0.504
E74.1 Disorders of fructose metabolism
0.000 0.496 0.504
E74.0 Glycogen storage disease
0.000 0.496 0.504
E11.3 With ophthalmic complications
0.000 0.504 0.496
M11 Other crystal arthropathies
0.000 0.508 0.492
E83.9 Disorder of mineral metabolism, unspecified
0.335 0.509 0.156
E83.8 Other disorders of mineral metabolism
0.335 0.509 0.156
E83.2 Disorders of zinc metabolism
0.335 0.509 0.156
E83.0 Disorders of copper metabolism
0.335 0.509 0.156
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.512 0.488
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.525 0.475
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.525 0.475
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.525 0.475
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.525 0.475
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.525 0.475
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.525 0.475
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.525 0.475
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.525 0.475
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.528 0.472
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.531 0.469
E16.2 Hypoglycaemia, unspecified
0.000 0.533 0.467
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.534 0.466
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.534 0.466
E70.3 Albinism
0.000 0.534 0.466
E70.2 Disorders of tyrosine metabolism
0.000 0.534 0.466
E70.1 Other hyperphenylalaninaemias
0.000 0.534 0.466
E70.0 Classical phenylketonuria
0.000 0.534 0.466
E71.3 Disorders of fatty-acid metabolism
0.000 0.534 0.466
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.534 0.466
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.534 0.466
E71.0 Maple-syrup-urine disease
0.000 0.534 0.466
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.534 0.466
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.534 0.466
E72.5 Disorders of glycine metabolism
0.000 0.534 0.466
E72.4 Disorders of ornithine metabolism
0.000 0.534 0.466
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.534 0.466
E72.2 Disorders of urea cycle metabolism
0.000 0.534 0.466
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.534 0.466
E72.0 Disorders of amino-acid transport
0.000 0.534 0.466
E75.6 Lipid storage disorder, unspecified
0.000 0.534 0.466
E75.5 Other lipid storage disorders
0.000 0.534 0.466
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.534 0.466
E75.3 Sphingolipidosis, unspecified
0.000 0.534 0.466
E75.2 Other sphingolipidosis
0.000 0.534 0.466
E75.1 Other gangliosidosis
0.000 0.534 0.466
E75.0 GM2 gangliosidosis
0.000 0.534 0.466
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.534 0.466
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.534 0.466
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.534 0.466
E76.2 Other mucopolysaccharidoses
0.000 0.534 0.466
E76.1 Mucopolysaccharidosis, type II
0.000 0.534 0.466
E76.0 Mucopolysaccharidosis, type I
0.000 0.534 0.466
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.534 0.466
E77.8 Other disorders of glycoprotein metabolism
0.000 0.534 0.466
E77.1 Defects in glycoprotein degradation
0.000 0.534 0.466
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.534 0.466
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.534 0.466
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.534 0.466
E79.1 Lesch-Nyhan syndrome
0.000 0.534 0.466
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.534 0.466
E84.9 Cystic fibrosis, unspecified
0.000 0.534 0.466
E84.8 Cystic fibrosis with other manifestations
0.000 0.534 0.466
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.534 0.466
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.534 0.466
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.536 0.464
M06.38 Rheumatoid nodule (Other)
0.000 0.536 0.464
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.536 0.464
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.536 0.464
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.536 0.464
M06.33 Rheumatoid nodule (Forearm)
0.000 0.536 0.464
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.536 0.464
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.536 0.464
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.536 0.464
I10 Essential (primary) hypertension
0.000 0.536 0.464
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.538 0.462
M12 Other specific arthropathies
0.000 0.539 0.461
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.539 0.461
M08 Juvenile arthritis
0.000 0.539 0.461
M14 Arthropathies in other diseases classified elsewhere
0.000 0.540 0.460
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.542 0.458
E45 Retarded development following protein-energy malnutrition
0.000 0.542 0.458
E43 Unspecified severe protein-energy malnutrition
0.000 0.542 0.458
E42 Marasmic kwashiorkor
0.000 0.542 0.458
E41 Nutritional marasmus
0.000 0.542 0.458
E40 Kwashiorkor
0.000 0.542 0.458
E83.3 Disorders of phosphorus metabolism
0.322 0.551 0.127
E46 Unspecified protein-energy malnutrition
0.000 0.555 0.445
I10-I15 Hypertensive diseases
0.000 0.556 0.444
L41.9 Parapsoriasis, unspecified
0.000 0.561 0.439
L41.8 Other parapsoriasis
0.000 0.561 0.439
L41.5 Retiform parapsoriasis
0.000 0.561 0.439
L41.4 Large plaque parapsoriasis
0.000 0.561 0.439
L41.3 Small plaque parapsoriasis
0.000 0.561 0.439
L41.2 Lymphomatoid papulosis
0.000 0.561 0.439
L41.1 Pityriasis lichenoides chronica
0.000 0.561 0.439
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.561 0.439
L44.9 Papulosquamous disorder, unspecified
0.000 0.561 0.439
L44.8 Other specified papulosquamous disorders
0.000 0.561 0.439
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.561 0.439
L44.3 Lichen ruber moniliformis
0.000 0.561 0.439
L44.2 Lichen striatus
0.000 0.561 0.439
L44.1 Lichen nitidus
0.000 0.561 0.439
L44.0 Pityriasis rubra pilaris
0.000 0.561 0.439
E03.8 Other specified hypothyroidism
0.000 0.563 0.437
E07 Other disorders of thyroid
0.000 0.568 0.432
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.572 0.428
M06.18 Adult-onset Still's disease (Other)
0.000 0.572 0.428
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.572 0.428
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.572 0.428
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.572 0.428
M06.14 Adult-onset Still's disease (Hand)
0.000 0.572 0.428
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.572 0.428
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.572 0.428
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.572 0.428
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.572 0.428
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.572 0.428
M06.28 Rheumatoid bursitis (Other)
0.000 0.572 0.428
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.572 0.428
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.572 0.428
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.572 0.428
M06.24 Rheumatoid bursitis (Hand)
0.000 0.572 0.428
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.572 0.428
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.572 0.428
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.572 0.428
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.572 0.428
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.572 0.428
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.572 0.428
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.572 0.428
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.572 0.428
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.572 0.428
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.572 0.428
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.572 0.428
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.572 0.428
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.572 0.428
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.572 0.428
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.573 0.427
E73.8 Other lactose intolerance
0.001 0.577 0.422
E73.1 Secondary lactase deficiency
0.001 0.577 0.422
E73.0 Congenital lactase deficiency
0.001 0.577 0.422
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.578 0.422
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.578 0.422
M10 Gout
0.000 0.579 0.421
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.580 0.419
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.582 0.418
E00 Congenital iodine-deficiency syndrome
0.000 0.582 0.418
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.582 0.418
E83.5 Disorders of calcium metabolism
0.395 0.583 0.023
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.587 0.413
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.587 0.413
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.587 0.413
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.587 0.413
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.587 0.413
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.587 0.413
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.587 0.413
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.587 0.413
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.587 0.413
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.588 0.411
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.588 0.411
E16.4 Abnormal secretion of gastrin
0.000 0.588 0.411
E16.3 Increased secretion of glucagon
0.000 0.588 0.411
E16.1 Other hypoglycaemia
0.000 0.588 0.411
M07.6 Other enteropathic arthropathies
0.000 0.589 0.411
M07.5 Arthropathy in ulcerative colitis
0.000 0.589 0.411
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.589 0.411
M07.2 Psoriatic spondylitis
0.000 0.589 0.411
M07.1 Arthritis mutilans
0.000 0.589 0.411
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.589 0.411
E89.3 Postprocedural hypopituitarism
0.000 0.589 0.411
E55 Vitamin D deficiency
0.000 0.592 0.408
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.593 0.407
G37 Other demyelinating diseases of central nervous system
0.400 0.599 0.000
E20-E35 Disorders of other endocrine glands
0.000 0.601 0.399
I12 Hypertensive renal disease
0.000 0.601 0.399
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.601 0.399
E80.6 Other disorders of bilirubin metabolism
0.000 0.601 0.399
E80.5 Crigler-Najjar syndrome
0.000 0.601 0.399
E80.3 Defects of catalase and peroxydase
0.000 0.601 0.399
E80.2 Other porphyria
0.000 0.601 0.399
E80.1 Porphyria cutanea tarda
0.000 0.601 0.399
E80.0 Hereditary erythropoietic porphyria
0.000 0.601 0.399
E61 Deficiency of other nutrient elements
0.000 0.602 0.398
E03.5 Myxoedema coma
0.000 0.605 0.395
E03.4 Atrophy of thyroid (acquired)
0.000 0.605 0.395
E03.3 Postinfectious hypothyroidism
0.000 0.605 0.395
E03.1 Congenital hypothyroidism without goitre
0.000 0.605 0.395
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.605 0.395
E88.9 Metabolic disorder, unspecified
0.000 0.605 0.394
E88.8 Other specified metabolic disorders
0.000 0.605 0.394
E88.3 Tumour lysis syndrome
0.000 0.605 0.394
E88.2 Lipomatosis, not elsewhere classified
0.000 0.605 0.394
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.607 0.393
Chapter IX Diseases of the circulatory system
0.000 0.608 0.392
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.611 0.389
E63 Other nutritional deficiencies
0.000 0.611 0.389
E56 Other vitamin deficiencies
0.000 0.611 0.389
E51 Thiamine deficiency
0.000 0.611 0.389
E50 Vitamin A deficiency
0.000 0.611 0.389
E60 Dietary zinc deficiency
0.000 0.611 0.389
E59 Dietary selenium deficiency
0.000 0.611 0.389
E58 Dietary calcium deficiency
0.000 0.611 0.389
E54 Ascorbic acid deficiency
0.000 0.611 0.389
E52 Niacin deficiency [pellagra]
0.000 0.611 0.389
M05.8 Other seropositive rheumatoid arthritis
0.000 0.615 0.385
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.615 0.385
M05.2 Rheumatoid vasculitis
0.000 0.615 0.385
M05.1 Rheumatoid lung disease
0.000 0.615 0.385
M05.0 Felty's syndrome
0.000 0.615 0.385
M11.2 Other chondrocalcinosis
0.000 0.616 0.384
M07.38 Other psoriatic arthropathies (Other)
0.000 0.624 0.375
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.624 0.375
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.624 0.375
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.624 0.375
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.624 0.375
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.624 0.375
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.624 0.375
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.624 0.375
G36 Other acute disseminated demyelination
0.371 0.628 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.634 0.366
I20.8 Other forms of angina pectoris
0.000 0.634 0.366
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.636 0.364
E73.9 Lactose intolerance, unspecified
0.001 0.638 0.361
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.639 0.361
M70-M79 Other soft tissue disorders
0.000 0.640 0.360
M45 Ankylosing spondylitis
0.000 0.642 0.358
M45-M49 Spondylopathies
0.000 0.642 0.358
I12.0 Hypertensive renal disease with renal failure
0.000 0.643 0.357
M75 Shoulder lesions
0.000 0.643 0.357
M11.9 Crystal arthropathy, unspecified
0.000 0.647 0.353
M11.8 Other specified crystal arthropathies
0.000 0.647 0.353
M11.1 Familial chondrocalcinosis
0.000 0.647 0.353
M11.0 Hydroxyapatite deposition disease
0.000 0.647 0.353
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.650 0.350
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.650 0.350
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.650 0.350
E89.5 Postprocedural testicular hypofunction
0.000 0.650 0.350
E89.4 Postprocedural ovarian failure
0.000 0.650 0.350
E89.1 Postprocedural hypoinsulinaemia
0.000 0.650 0.350
M75.0 Adhesive capsulitis of shoulder
0.000 0.651 0.349
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.656 0.344
M79 Other soft tissue disorders, not elsewhere classified
0.000 0.657 0.343
I11 Hypertensive heart disease
0.000 0.660 0.340
M75.1 Rotator cuff syndrome
0.000 0.663 0.337
M79.65 Pain in limb (Pelvic region and thigh)
0.000 0.664 0.336
M79.6 Pain in limb
0.000 0.665 0.335
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.666 0.334
E88.1 Lipodystrophy, not elsewhere classified
0.001 0.667 0.333
I15 Secondary hypertension
0.000 0.668 0.331
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.669 0.331
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.669 0.331
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.669 0.331
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.669 0.331
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.669 0.331
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.669 0.331
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.669 0.331
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.669 0.331
M08.9 Juvenile arthritis, unspecified
0.000 0.669 0.330
M08.8 Other juvenile arthritis
0.000 0.669 0.330
M08.4 Pauciarticular juvenile arthritis
0.000 0.669 0.330
M08.3 Juvenile polyarthritis (seronegative)
0.000 0.669 0.330
M08.2 Juvenile arthritis with systemic onset
0.000 0.669 0.330
M08.1 Juvenile ankylosing spondylitis
0.000 0.669 0.330
M08.0 Juvenile rheumatoid arthritis
0.000 0.669 0.330
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.000 0.669 0.330
M09.2 Juvenile arthritis in ulcerative colitis
0.000 0.669 0.330
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.000 0.669 0.330
M09.0 Juvenile arthritis in psoriasis
0.000 0.669 0.330
M12.8 Other specific arthropathies, not elsewhere classified
0.000 0.669 0.330
M12.5 Traumatic arthropathy
0.000 0.669 0.330
M12.4 Intermittent hydrarthrosis
0.000 0.669 0.330
M12.3 Palindromic rheumatism
0.000 0.669 0.330
M12.2 Villonodular synovitis (pigmented)
0.000 0.669 0.330
M12.1 Kaschin-Beck disease
0.000 0.669 0.330
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.000 0.669 0.330
M14.8 Arthropathies in other specified diseases classified elsewhere
0.000 0.670 0.330
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.000 0.670 0.330
M14.4 Arthropathy in amyloidosis
0.000 0.670 0.330
M14.3 Lipoid dermatoarthritis
0.000 0.670 0.330
M14.2 Diabetic arthropathy
0.000 0.670 0.330
M14.1 Crystal arthropathy in other metabolic disorders
0.000 0.670 0.330
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.000 0.670 0.330
G37.9 Demyelinating disease of central nervous system, unspecified
0.329 0.671 0.000
M14.6 Neuropathic arthropathy
0.000 0.671 0.329
E44.1 Mild protein-energy malnutrition
0.000 0.671 0.328
E44.0 Moderate protein-energy malnutrition
0.000 0.671 0.328
M46 Other inflammatory spondylopathies
0.000 0.675 0.325
E83.4 Disorders of magnesium metabolism
0.144 0.678 0.178
E07.9 Disorder of thyroid, unspecified
0.000 0.679 0.321
E24 Cushing's syndrome
0.000 0.679 0.321
E28 Ovarian dysfunction
0.000 0.681 0.319
I13 Hypertensive heart and renal disease
0.000 0.681 0.319
E22 Hyperfunction of pituitary gland
0.000 0.683 0.317
E65-E68 Obesity and other hyperalimentation
0.000 0.684 0.316
E61.1 Iron deficiency
0.000 0.685 0.315
M79.7 Fibromyalgia
0.000 0.685 0.315
E07.8 Other specified disorders of thyroid
0.000 0.687 0.313
E55.9 Vitamin D deficiency, unspecified
0.000 0.689 0.311
I12.9 Hypertensive renal disease without renal failure
0.000 0.689 0.311
G37.8 Other specified demyelinating diseases of central nervous system
0.310 0.690 0.000
E07.1 Dyshormogenetic goitre
0.000 0.690 0.310
E07.0 Hypersecretion of calcitonin
0.000 0.690 0.310
M75.4 Impingement syndrome of shoulder
0.000 0.692 0.308

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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