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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2430193
log Bayes Factor = 14.5977
Chromosome 5   position 141,788,679  (GRCh37) Explore rs2430193 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter II Neoplasms
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
D10-D36 Benign neoplasms
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E11 Non-insulin-dependent diabetes mellitus
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.998 0.002 0.000
E11.9 Without complications
0.995 0.005 0.000
Chapter VII Diseases of the eye and adnexa
0.989 0.011 0.000
Chapter XXI Factors influencing health status and contact with health services
0.989 0.011 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.988 0.012 0.000
Z51 Other medical care
0.985 0.015 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.982 0.018 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.980 0.020 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.977 0.023 0.000
Z51.1 Chemotherapy session for neoplasm
0.974 0.026 0.000
Chapter XIV Diseases of the genitourinary system
0.969 0.031 0.000
E70-E90 Metabolic disorders
0.967 0.033 0.000
Chapter I Certain infectious and parasitic diseases
0.965 0.035 0.000
N17-N19 Renal failure
0.964 0.036 0.000
Chapter IX Diseases of the circulatory system
0.962 0.038 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.959 0.041 0.000
N18 Chronic renal failure
0.953 0.047 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.946 0.054 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.942 0.058 0.000
H25-H28 Disorders of lens
0.940 0.060 0.000
M20-M25 Other joint disorders
0.928 0.072 0.000
D12.6 Colon, unspecified
0.923 0.077 0.000
E87.6 Hypokalaemia
0.922 0.078 0.000
D27 Benign neoplasm of ovary
0.920 0.080 0.000
D00-D09 In situ neoplasms
0.917 0.083 0.000
N60-N64 Disorders of breast
0.913 0.087 0.000
E50-E64 Other nutritional deficiencies
0.909 0.091 0.000
H25 Senile cataract
0.906 0.094 0.000
N18.3 Chronic kidney disease, stage 3
0.906 0.094 0.000
H30-H36 Disorders of choroid and retina
0.903 0.097 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.901 0.098 0.000
Chapter XX External causes of morbidity and mortality
0.901 0.099 0.000
D22 Melanocytic naevi
0.899 0.101 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.894 0.106 0.000
E11.3 With ophthalmic complications
0.891 0.109 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.890 0.110 0.000
E11.2 With renal complications
0.888 0.112 0.000
D17 Benign lipomatous neoplasm
0.887 0.113 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.880 0.120 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.879 0.121 0.000
Z51.0 Radiotherapy session
0.876 0.124 0.000
C64-C68 Malignant neoplasms of urinary tract
0.871 0.129 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.871 0.129 0.000
M20 Acquired deformities of fingers and toes
0.866 0.134 0.000
D23 Other benign neoplasms of skin
0.864 0.136 0.000
E83 Disorders of mineral metabolism
0.864 0.136 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.862 0.138 0.000
Z40 Prophylactic surgery
0.859 0.141 0.000
N19 Unspecified renal failure
0.859 0.141 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.859 0.141 0.000
E11.4 With neurological complications
0.858 0.142 0.000
D18 Haemangioma and lymphangioma, any site
0.858 0.142 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.852 0.148 0.000
Z51.5 Palliative care
0.847 0.153 0.000
B25-B34 Other viral diseases
0.846 0.154 0.000
E10 Insulin-dependent diabetes mellitus
0.846 0.154 0.000
H25.0 Senile incipient cataract
0.843 0.157 0.000
B35-B49 Mycoses
0.842 0.158 0.000
D12.2 Ascending colon
0.838 0.162 0.000
N18.5 Chronic kidney disease, stage 5
0.838 0.162 0.000
M45-M49 Spondylopathies
0.837 0.163 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.837 0.163 0.000
N00-N08 Glomerular diseases
0.835 0.165 0.000
H33 Retinal detachments and breaks
0.832 0.168 0.000
Chapter XI Diseases of the digestive system
0.832 0.168 0.000
M40-M43 Deforming dorsopathies
0.831 0.169 0.000
D30 Benign neoplasm of urinary organs
0.827 0.173 0.000
Z41 Procedures for purposes other than remedying health state
0.826 0.174 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.824 0.176 0.000
Z49 Care involving dialysis
0.821 0.179 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.821 0.179 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.820 0.180 0.000
S40-S49 Injuries to the shoulder and upper arm
0.819 0.181 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.819 0.181 0.000
D12.4 Descending colon
0.818 0.182 0.000
I73 Other peripheral vascular diseases
0.816 0.184 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.815 0.185 0.000
D05 Carcinoma in situ of breast
0.814 0.186 0.000
B15-B19 Viral hepatitis
0.812 0.188 0.000
E11.5 With peripheral circulatory complications
0.812 0.188 0.000
Z54 Convalescence
0.811 0.189 0.000
D12.8 Rectum
0.811 0.189 0.000
C15-C26 Malignant neoplasms of digestive organs
0.810 0.190 0.000
M86-M90 Other osteopathies
0.810 0.190 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.809 0.191 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.809 0.191 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.807 0.193 0.000
M91-M94 Chondropathies
0.807 0.193 0.000
N62 Hypertrophy of breast
0.807 0.193 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.807 0.193 0.000
E55 Vitamin D deficiency
0.802 0.197 0.000
M20.2 Hallux rigidus
0.802 0.198 0.000
I26 Pulmonary embolism
0.800 0.200 0.000
S70-S79 Injuries to the hip and thigh
0.800 0.200 0.000
H25.8 Other senile cataract
0.796 0.204 0.000
C43 Malignant melanoma of skin
0.796 0.204 0.000
H55-H59 Other disorders of eye and adnexa
0.795 0.205 0.000
M22 Disorders of patella
0.794 0.206 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.794 0.206 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.794 0.206 0.000
I10-I15 Hypertensive diseases
0.793 0.207 0.000
T86 Failure and rejection of transplanted organs and tissues
0.791 0.209 0.000
A00-A09 Intestinal infectious diseases
0.790 0.210 0.000
I95 Hypotension
0.790 0.210 0.000
Chapter XXII Codes for special purposes
0.789 0.211 0.000
C51-C58 Malignant neoplasms of female genital organs
0.789 0.211 0.000
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk
0.788 0.212 0.000
Z51.3 Blood transfusion without reported diagnosis
0.787 0.213 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.783 0.217 0.000
D23.1 Skin of eyelid, including canthus
0.782 0.218 0.000
M21 Other acquired deformities of limbs
0.781 0.219 0.000
M80-M85 Disorders of bone density and structure
0.780 0.220 0.000
W20-W49 Exposure to inanimate mechanical forces
0.780 0.220 0.000
E83.4 Disorders of magnesium metabolism
0.779 0.221 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.778 0.222 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.778 0.222 0.000
Z42 Follow-up care involving plastic surgery
0.776 0.224 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.775 0.225 0.000
E13 Other specified diabetes mellitus
0.774 0.226 0.000
D26 Other benign neoplasms of uterus
0.772 0.228 0.000
I95.1 Orthostatic hypotension
0.771 0.229 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.770 0.230 0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms
0.767 0.233 0.000
N60 Benign mammary dysplasia
0.765 0.235 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.764 0.236 0.000
B34 Viral infection of unspecified site
0.761 0.239 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.761 0.239 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.759 0.241 0.000
I60-I69 Cerebrovascular diseases
0.758 0.242 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.757 0.243 0.000
I12 Hypertensive renal disease
0.757 0.243 0.000
C25 Malignant neoplasm of pancreas
0.757 0.243 0.000
E14 Unspecified diabetes mellitus
0.756 0.244 0.000
D18.0 Haemangioma, any site
0.756 0.244 0.000
D22.5 Melanocytic naevi of trunk
0.755 0.245 0.000
Z48 Other surgical follow-up care
0.754 0.246 0.000
B37 Candidiasis
0.753 0.247 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.752 0.248 0.000
Z43 Attention to artificial openings
0.750 0.250 0.000
D32 Benign neoplasm of meninges
0.749 0.251 0.000
E53 Deficiency of other B group vitamins
0.749 0.251 0.000
I73.9 Peripheral vascular disease, unspecified
0.749 0.251 0.000
N64 Other disorders of breast
0.748 0.252 0.000
N18.9 Chronic renal failure, unspecified
0.748 0.252 0.000
Z45 Adjustment and management of implanted device
0.748 0.252 0.000
T18 Foreign body in alimentary tract
0.747 0.253 0.000
H33.2 Serous retinal detachment
0.746 0.254 0.000
N18.4 Chronic kidney disease, stage 4
0.746 0.254 0.000
Chapter V Mental and behavioural disorders
0.745 0.255 0.000
M35 Other systemic involvement of connective tissue
0.744 0.256 0.000
S90-S99 Injuries to the ankle and foot
0.744 0.256 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.743 0.257 0.000
K04 Diseases of pulp and periapical tissues
0.743 0.257 0.000
H34 Retinal vascular occlusions
0.742 0.258 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.740 0.259 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.740 0.260 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.740 0.260 0.000
H40-H42 Glaucoma
0.738 0.262 0.000
K02 Dental caries
0.737 0.263 0.000
D22.3 Melanocytic naevi of other and unspecified parts of face
0.737 0.263 0.000
D36 Benign neoplasm of other and unspecified sites
0.735 0.265 0.000
D12.3 Transverse colon
0.735 0.265 0.000
D22.4 Melanocytic naevi of scalp and neck
0.734 0.266 0.000
E20-E35 Disorders of other endocrine glands
0.731 0.269 0.000
T51 Toxic effect of alcohol
0.731 0.269 0.000
A04 Other bacterial intestinal infections
0.730 0.270 0.000
N18.0 End-stage renal disease
0.730 0.270 0.000
H53-H54 Visual disturbances and blindness
0.729 0.271 0.000
N18.2 Chronic kidney disease, stage 2
0.727 0.273 0.000
E55.9 Vitamin D deficiency, unspecified
0.726 0.274 0.000
S50-S59 Injuries to the elbow and forearm
0.726 0.274 0.000
D05.1 Intraductal carcinoma in situ
0.726 0.274 0.000
D03 Melanoma in situ
0.725 0.275 0.000
E10.9 Without complications
0.724 0.276 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.723 0.277 0.000
Z47 Other orthopaedic follow-up care
0.723 0.277 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.721 0.279 0.000
A80-A89 Viral infections of the central nervous system
0.720 0.280 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.720 0.280 0.000
I12.0 Hypertensive renal disease with renal failure
0.720 0.280 0.000
D13.1 Stomach
0.720 0.280 0.000
D09 Carcinoma in situ of other and unspecified sites
0.719 0.281 0.000
S80-S89 Injuries to the knee and lower leg
0.719 0.281 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.718 0.282 0.000
D17.0 Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck
0.718 0.282 0.000
Y95 Nosocomial condition
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.717 0.283 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E40-E46 Malnutrition
0.717 0.283 0.000
D31 Benign neoplasm of eye and adnexa
0.717 0.283 0.000
D29 Benign neoplasm of male genital organs
0.717 0.283 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.717 0.283 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.717 0.283 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.717 0.283 0.000
D19 Benign neoplasm of mesothelial tissue
0.717 0.283 0.000
D16 Benign neoplasm of bone and articular cartilage
0.717 0.283 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.717 0.283 0.000
D10 Benign neoplasm of mouth and pharynx
0.717 0.283 0.000
D34 Benign neoplasm of thyroid gland
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
E11.8 With unspecified complications
0.717 0.283 0.000
E11.7 With multiple complications
0.717 0.283 0.000
E11.6 With other specified complications
0.717 0.283 0.000
E11.1 With ketoacidosis
0.717 0.283 0.000
E11.0 With coma
0.717 0.283 0.000
K13 Other diseases of lip and oral mucosa
0.716 0.284 0.000
T33-T35 Frostbite
0.715 0.285 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.715 0.285 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.715 0.285 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.715 0.285 0.000
T00-T07 Injuries involving multiple body regions
0.715 0.285 0.000
S10-S19 Injuries to the neck
0.715 0.285 0.000
M65-M68 Disorders of synovium and tendon
0.715 0.285 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.714 0.285 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.714 0.286 0.000
T79-T79 Certain early complications of trauma
0.714 0.286 0.000
I05-I09 Chronic rheumatic heart diseases
0.714 0.286 0.000
C60-C63 Malignant neoplasms of male genital organs
0.713 0.287 0.000
T66-T78 Other and unspecified effects of external causes
0.713 0.287 0.000
M70-M79 Other soft tissue disorders
0.713 0.287 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.712 0.288 0.000
I71 Aortic aneurysm and dissection
0.711 0.289 0.000
Z93 Artificial opening status
0.710 0.290 0.000
Z41.1 Other plastic surgery for unacceptable cosmetic appearance
0.710 0.290 0.000
E87.7 Fluid overload
0.710 0.290 0.000
N17 Acute renal failure
0.710 0.290 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.709 0.291 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.709 0.291 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.709 0.291 0.000
Z52 Donors of organs and tissues
0.708 0.292 0.000
Z44 Fitting and adjustment of external prosthetic device
0.708 0.292 0.000
B95-B98 Bacterial, viral and other infectious agents
0.707 0.293 0.000
Z51.9 Medical care, unspecified
0.706 0.294 0.000
Z51.6 Desensitisation to allergens
0.706 0.294 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.706 0.294 0.000
H10-H13 Disorders of conjunctiva
0.706 0.294 0.000
M43 Other deforming dorsopathies
0.705 0.295 0.000
T87 Complications peculiar to reattachment and amputation
0.704 0.296 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.704 0.296 0.000
D30.3 Bladder
0.703 0.297 0.000
M60-M63 Disorders of muscles
0.703 0.297 0.000
M00-M03 Infectious arthropathies
0.703 0.297 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.702 0.298 0.000
N99-N99 Other disorders of the genitourinary system
0.702 0.298 0.000
H43-H45 Disorders of vitreous body and globe
0.701 0.299 0.000
D12.9 Anus and anal canal
0.700 0.299 0.000
D12.1 Appendix
0.700 0.299 0.000
B34.9 Viral infection, unspecified
0.700 0.300 0.000
E88 Other metabolic disorders
0.699 0.301 0.000
I27 Other pulmonary heart diseases
0.697 0.303 0.000
C44 Other malignant neoplasms of skin
0.697 0.303 0.000
D22.1 Melanocytic naevi of eyelid, including canthus
0.695 0.305 0.000
M20.5 Other deformities of toe(s) (acquired)
0.694 0.306 0.000
D04 Carcinoma in situ of skin
0.693 0.307 0.000
E85 Amyloidosis
0.693 0.307 0.000
E84 Cystic fibrosis
0.693 0.307 0.000
E79 Disorders of purine and pyrimidine metabolism
0.693 0.307 0.000
E77 Disorders of glycoprotein metabolism
0.693 0.307 0.000
E76 Disorders of glycosaminoglycan metabolism
0.693 0.307 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.693 0.307 0.000
E74 Other disorders of carbohydrate metabolism
0.693 0.307 0.000
E73 Lactose intolerance
0.693 0.307 0.000
E72 Other disorders of amino-acid metabolism
0.693 0.307 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.693 0.307 0.000
E70 Disorders of aromatic amino-acid metabolism
0.693 0.307 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.693 0.307 0.000
S20-S29 Injuries to the thorax
0.692 0.308 0.000
B99-B99 Other infectious diseases
0.692 0.308 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.692 0.308 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.692 0.308 0.000
B65-B83 Helminthiases
0.692 0.308 0.000
B50-B64 Protozoal diseases
0.692 0.308 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.692 0.308 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.692 0.308 0.000
A75-A79 Rickettsioses
0.692 0.308 0.000
A70-A74 Other diseases caused by chlamydiae
0.692 0.308 0.000
A65-A69 Other spirochaetal diseases
0.692 0.308 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.692 0.308 0.000
A20-A28 Certain zoonotic bacterial diseases
0.692 0.308 0.000
A15-A19 Tuberculosis
0.692 0.308 0.000
D23.4 Skin of scalp and neck
0.692 0.308 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.690 0.310 0.000
I00-I02 Acute rheumatic fever
0.690 0.310 0.000
H36 Retinal disorders in diseases classified elsewhere
0.689 0.311 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.687 0.313 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.687 0.313 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.687 0.313 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.687 0.313 0.000
Z22 Carrier of infectious disease
0.686 0.314 0.000
Z54.0 Convalescence following surgery
0.685 0.315 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.684 0.316 0.000
T43.2 Other and unspecified antidepressants
0.684 0.316 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.683 0.317 0.000
N18.8 Other chronic renal failure
0.683 0.317 0.000
N18.1 Chronic kidney disease, stage 1
0.683 0.317 0.000
K12 Stomatitis and related lesions
0.683 0.317 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.682 0.318 0.000
H25.9 Senile cataract, unspecified
0.682 0.318 0.000
E87.4 Mixed disorder of acid-base balance
0.678 0.322 0.000
E87.3 Alkalosis
0.678 0.322 0.000
K02.9 Dental caries, unspecified
0.677 0.323 0.000
C25.9 Pancreas, unspecified
0.677 0.323 0.000
D12.0 Caecum
0.677 0.323 0.000
D22.6 Melanocytic naevi of upper limb, including shoulder
0.676 0.323 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.674 0.326 0.000
H27 Other disorders of lens
0.674 0.326 0.000
Chapter VIII Diseases of the ear and mastoid process
0.674 0.326 0.000
D11 Benign neoplasm of major salivary glands
0.674 0.326 0.000
N61 Inflammatory disorders of breast
0.674 0.326 0.000
L20-L30 Dermatitis and eczema
0.673 0.327 0.000
D14.0 Middle ear, nasal cavity and accessory sinuses
0.673 0.327 0.000
D12.7 Rectosigmoid junction
0.672 0.328 0.000
T18.1 Foreign body in oesophagus
0.672 0.328 0.000
E83.3 Disorders of phosphorus metabolism
0.669 0.331 0.000
T63 Toxic effect of contact with venomous animals
0.669 0.331 0.000
C43.5 Malignant melanoma of trunk
0.668 0.332 0.000
Z49.1 Extracorporeal dialysis
0.668 0.332 0.000
N20-N23 Urolithiasis
0.667 0.333 0.000
Z89 Acquired absence of limb
0.667 0.333 0.000
M48 Other spondylopathies
0.667 0.333 0.000
I30-I52 Other forms of heart disease
0.667 0.333 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.666 0.334 0.000
M34 Systemic sclerosis
0.666 0.334 0.000
M33 Dermatopolymyositis
0.666 0.334 0.000
M32 Systemic lupus erythematosus
0.666 0.334 0.000
M30 Polyarteritis nodosa and related conditions
0.666 0.334 0.000
H33.0 Retinal detachment with retinal break
0.665 0.335 0.000
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs
0.664 0.335 0.000
I73.0 Raynaud's syndrome
0.664 0.336 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.663 0.337 0.000
H26 Other cataract
0.663 0.337 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.663 0.337 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.663 0.337 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.662 0.338 0.000
E00-E07 Disorders of thyroid gland
0.662 0.338 0.000
K20 Oesophagitis
0.661 0.339 0.000
B18 Chronic viral hepatitis
0.661 0.339 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.660 0.340 0.000
M93 Other osteochondropathies
0.660 0.340 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.659 0.341 0.000
M87 Osteonecrosis
0.658 0.341 0.000
N76 Other inflammation of vagina and vulva
0.658 0.342 0.000
D37.4 Colon
0.658 0.342 0.000
E87.0 Hyperosmolality and hypernatraemia
0.657 0.342 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.657 0.343 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.657 0.343 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.657 0.343 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.657 0.343 0.000
E61 Deficiency of other nutrient elements
0.655 0.345 0.000
T86.1 Kidney transplant failure and rejection
0.654 0.346 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.654 0.346 0.000
C25.0 Head of pancreas
0.654 0.346 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.653 0.347 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.652 0.348 0.000
E63 Other nutritional deficiencies
0.652 0.348 0.000
E56 Other vitamin deficiencies
0.652 0.348 0.000
E51 Thiamine deficiency
0.652 0.348 0.000
E50 Vitamin A deficiency
0.652 0.348 0.000
E60 Dietary zinc deficiency
0.652 0.348 0.000
E59 Dietary selenium deficiency
0.652 0.348 0.000
E58 Dietary calcium deficiency
0.652 0.348 0.000
E54 Ascorbic acid deficiency
0.652 0.348 0.000
E52 Niacin deficiency [pellagra]
0.652 0.348 0.000
M22.8 Other disorders of patella
0.651 0.348 0.000
S42 Fracture of shoulder and upper arm
0.651 0.349 0.000
M47 Spondylosis
0.651 0.349 0.000
Z51.8 Other specified medical care
0.651 0.349 0.000
H25.2 Senile cataract, morgagnian type
0.650 0.350 0.000
L90 Atrophic disorders of skin
0.648 0.352 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.648 0.352 0.000
H31 Other disorders of choroid
0.648 0.352 0.000
H30 Chorioretinal inflammation
0.648 0.352 0.000
B17 Other acute viral hepatitis
0.646 0.353 0.000
D46 Myelodysplastic syndromes
0.646 0.354 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.646 0.354 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.646 0.354 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.646 0.354 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.646 0.354 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.646 0.354 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.646 0.354 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.646 0.354 0.000
Y35-Y36 Legal intervention and operations of war
0.646 0.354 0.000
Y10-Y34 Event of undetermined intent
0.646 0.354 0.000
Y00-Y09 Assault
0.646 0.354 0.000
X85-X99 Assault
0.646 0.354 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.646 0.354 0.000
X50-X57 Overexertion, travel and privation
0.646 0.354 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.646 0.354 0.000
X30-X39 Exposure to forces of nature
0.646 0.354 0.000
X20-X29 Contact with venomous animals and plants
0.646 0.354 0.000
X10-X19 Contact with heat and hot substances
0.646 0.354 0.000
X00-X09 Exposure to smoke, fire and flames
0.646 0.354 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.646 0.354 0.000
W75-W84 Other accidental threats to breathing
0.646 0.354 0.000
W65-W74 Accidental drowning and submersion
0.646 0.354 0.000
W50-W64 Exposure to animate mechanical forces
0.646 0.354 0.000
V98-V99 Other and unspecified transport accidents
0.646 0.354 0.000
V95-V97 Air and space transport accidents
0.646 0.354 0.000
V90-V94 Water transport accidents
0.646 0.354 0.000
V80-V89 Other land transport accidents
0.646 0.354 0.000
V70-V79 Bus occupant injured in transport accident
0.646 0.354 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.646 0.354 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.646 0.354 0.000
V40-V49 Car occupant injured in transport accident
0.646 0.354 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.646 0.354 0.000
V01-V09 Pedestrian injured in transport accident
0.646 0.354 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.645 0.355 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.645 0.355 0.000
D22.9 Melanocytic naevi, unspecified
0.644 0.355 0.000
D22.2 Melanocytic naevi of ear and external auricular canal
0.644 0.355 0.000
D22.0 Melanocytic naevi of lip
0.644 0.355 0.000
H25.1 Senile nuclear cataract
0.644 0.356 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.644 0.356 0.000
V20-V29 Motorcycle rider injured in transport accident
0.644 0.356 0.000
K08 Other disorders of teeth and supporting structures
0.644 0.356 0.000
S72 Fracture of femur
0.643 0.357 0.000
V10-V19 Pedal cyclist injured in transport accident
0.643 0.357 0.000
Chapter VI Diseases of the nervous system
0.642 0.358 0.000
D17.9 Benign lipomatous neoplasm, unspecified
0.642 0.358 0.000
C43.7 Malignant melanoma of lower limb, including hip
0.641 0.359 0.000
Z49.0 Preparatory care for dialysis
0.641 0.359 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.641 0.359 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.639 0.361 0.000
T90 Sequelae of injuries of head
0.639 0.361 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.638 0.361 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.638 0.361 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.638 0.361 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.638 0.361 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.638 0.361 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.638 0.361 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.638 0.361 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.638 0.361 0.000
T36 Poisoning by systemic antibiotics
0.638 0.361 0.000
X60-X84 Intentional self-harm
0.638 0.362 0.000
M35.0 Sicca syndrome [Sjogren]
0.638 0.362 0.000
E10.1 With ketoacidosis
0.638 0.362 0.000
M45 Ankylosing spondylitis
0.637 0.363 0.000
M22.2 Patellofemoral disorders
0.637 0.363 0.000
B37.3 Candidiasis of vulva and vagina
0.637 0.363 0.000
D17.7 Benign lipomatous neoplasm of other sites
0.636 0.364 0.000
D17.5 Benign lipomatous neoplasm of intra-abdominal organs
0.636 0.364 0.000
D17.4 Benign lipomatous neoplasm of intrathoracic organs
0.636 0.364 0.000
Z93.6 Other artificial openings of urinary tract status
0.636 0.364 0.000
K04.7 Periapical abscess without sinus
0.636 0.364 0.000
B37.0 Candidal stomatitis
0.635 0.365 0.000
E53.8 Deficiency of other specified B group vitamins
0.635 0.365 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.635 0.365 0.000
H33.3 Retinal breaks without detachment
0.635 0.365 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.634 0.365 0.000
W44 Foreign body entering into or through eye or natural orifice
0.634 0.366 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.634 0.366 0.000
M41 Scoliosis
0.633 0.367 0.000
M24 Other specific joint derangements
0.633 0.367 0.000
M20.1 Hallux valgus (acquired)
0.633 0.367 0.000
N73 Other female pelvic inflammatory diseases
0.632 0.368 0.000
E87.5 Hyperkalaemia
0.632 0.368 0.000
M21.2 Flexion deformity
0.631 0.368 0.000
I28 Other diseases of pulmonary vessels
0.631 0.369 0.000
M20.3 Other deformity of hallux (acquired)
0.631 0.369 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.630 0.370 0.000
I72 Other aneurysm
0.630 0.370 0.000
I70 Atherosclerosis
0.630 0.370 0.000
M80 Osteoporosis with pathological fracture
0.630 0.370 0.000
N60.0 Solitary cyst of breast
0.630 0.370 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.629 0.370 0.000
N04 Nephrotic syndrome
0.629 0.371 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.628 0.372 0.000
D23.7 Skin of lower limb, including hip
0.627 0.373 0.000
M20.4 Other hammer toe(s) (acquired)
0.626 0.374 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.626 0.374 0.000
A04.8 Other specified bacterial intestinal infections
0.626 0.374 0.000
Z93.2 Ileostomy status
0.626 0.374 0.000
M89 Other disorders of bone
0.626 0.374 0.000
E87.2 Acidosis
0.625 0.374 0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.625 0.375 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.625 0.375 0.000
C66 Malignant neoplasm of ureter
0.625 0.375 0.000
C65 Malignant neoplasm of renal pelvis
0.625 0.375 0.000
D41.0 Kidney
0.625 0.375 0.000
Z42.1 Follow-up care involving plastic surgery of breast
0.625 0.375 0.000
Z94 Transplanted organ and tissue status
0.624 0.376 0.000
M31 Other necrotising vasculopathies
0.624 0.376 0.000
Z83 Family history of other specific disorders
0.624 0.376 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.624 0.376 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.623 0.376 0.000
D05.9 Carcinoma in situ of breast, unspecified
0.623 0.377 0.000
M46 Other inflammatory spondylopathies
0.623 0.377 0.000
A04.7 Enterocolitis due to Clostridium difficile
0.623 0.377 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.622 0.378 0.000
I78 Diseases of capillaries
0.622 0.378 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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