TreeWAS – Variant ID: rs2517456

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter II Neoplasms	1.000	0.000
# Top node	1.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	1.000	0.000
C44 Other malignant neoplasms of skin	1.000	0.000
E00-E07 Disorders of thyroid gland	0.999	0.001
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.999	0.001
D10-D36 Benign neoplasms	0.998	0.002
E03 Other hypothyroidism	0.998	0.002
E03.9 Hypothyroidism, unspecified	0.998	0.002
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.997	0.003
C44.3 Skin of other and unspecified parts of face	0.996	0.004
Chapter XIV Diseases of the genitourinary system	0.996	0.004
Chapter XXI Factors influencing health status and contact with health services	0.996	0.004
Chapter XI Diseases of the digestive system	0.994	0.006
K20-K31 Diseases of oesophagus, stomach and duodenum	0.993	0.007
Chapter XII Diseases of the skin and subcutaneous tissue	0.991	0.009
N20-N23 Urolithiasis	0.990	0.010
K20 Oesophagitis	0.984	0.016
N20 Calculus of kidney and ureter	0.981	0.019
S60-S69 Injuries to the wrist and hand	0.979	0.021
Chapter IX Diseases of the circulatory system	0.975	0.025
N17-N19 Renal failure	0.974	0.026
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.974	0.026
M15-M19 Arthrosis	0.972	0.028
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.968	0.032
M19 Other arthrosis	0.968	0.032
I20-I25 Ischaemic heart diseases	0.966	0.034
Z95 Presence of cardiac and vascular implants and grafts	0.963	0.037
L80-L99 Other disorders of the skin and subcutaneous tissue	0.962	0.038
K26 Duodenal ulcer	0.961	0.039
M05-M14 Inflammatory polyarthropathies	0.958	0.042
Z00-Z13 Persons encountering health services for examination and investigation	0.955	0.045
M19.9 Arthrosis, unspecified	0.954	0.046
N19 Unspecified renal failure	0.952	0.048
C44.4 Skin of scalp and neck	0.950	0.050
N20.0 Calculus of kidney	0.949	0.051
Z88 Personal history of allergy to drugs, medicaments and biologocal substances	0.947	0.053
S61 Open wound of wrist and hand	0.946	0.054
E70-E90 Metabolic disorders	0.943	0.057
E20-E35 Disorders of other endocrine glands	0.942	0.058
D22 Melanocytic naevi	0.941	0.059
Z08 Follow-up examination after treatment for malignant neoplasm	0.937	0.063
Z88.0 Personal history of allergy to penicillin	0.936	0.064
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.935	0.065
D23 Other benign neoplasms of skin	0.931	0.069
Chapter XX External causes of morbidity and mortality	0.928	0.072
I25 Chronic ischaemic heart disease	0.926	0.074
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.922	0.078
Z95.2 Presence of prosthetic heart valve	0.921	0.079
Z85 Personal history of malignant neoplasm	0.921	0.079
D37-D48 Neoplasms of uncertain or unknown behaviour	0.919	0.081
L00-L08 Infections of the skin and subcutaneous tissue	0.919	0.081
Chapter VII Diseases of the eye and adnexa	0.917	0.083
I24 Other acute ischaemic heart diseases	0.914	0.086
Z95.1 Presence of aortocoronary bypass graft	0.911	0.089
S61.0 Open wound of finger(s) without damage to nail	0.910	0.090
I25.9 Chronic ischaemic heart disease, unspecified	0.904	0.096
K22 Other diseases of oesophagus	0.903	0.097
Z85.8 Personal history of malignant neoplasms of other organs and systems	0.903	0.097
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified	0.902	0.098
H40-H42 Glaucoma	0.900	0.100
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.899	0.101
M13 Other arthritis	0.898	0.102
M19.99 Arthrosis, unspecified (Site unspecified)	0.898	0.102
Chapter V Mental and behavioural disorders	0.896	0.104
K04 Diseases of pulp and periapical tissues	0.894	0.106
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.894	0.106
L40-L45 Papulosquamous disorders	0.888	0.112
H40 Glaucoma	0.888	0.112
D18 Haemangioma and lymphangioma, any site	0.886	0.114
M45-M49 Spondylopathies	0.886	0.114
L03 Cellulitis	0.882	0.118
C44.1 Skin of eyelid, including canthus	0.882	0.118
N23 Unspecified renal colic	0.881	0.119
L82 Seborrhoeic keratosis	0.872	0.128
Z88.5 Personal history of allergy to narcotic agent	0.872	0.128
M19.0 Primary arthrosis of other joints	0.868	0.132
D12.4 Descending colon	0.865	0.135
Z08.0 Follow-up examination after surgery for malignant neoplasm	0.865	0.135
S00-S09 Injuries to the head	0.863	0.137
D22.3 Melanocytic naevi of other and unspecified parts of face	0.861	0.139
K30 Dyspepsia	0.860	0.140
Z08.7 Follow-up examination after combined treatment for malignant neoplasm	0.859	0.141
D23.1 Skin of eyelid, including canthus	0.857	0.143
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.857	0.143
K07 Dentofacial anomalies [including malocclusion]	0.856	0.144
Z95.5 Presence of coronary angioplasty implant and graft	0.854	0.146
K50-K52 Noninfective enteritis and colitis	0.852	0.148
Z13 Special screening examination for other diseases and disorders	0.852	0.148
I70-I79 Diseases of arteries, arterioles and capillaries	0.851	0.149
N20.2 Calculus of kidney with calculus of ureter	0.848	0.152
Z93 Artificial opening status	0.846	0.154
S20-S29 Injuries to the thorax	0.845	0.155
S50-S59 Injuries to the elbow and forearm	0.843	0.157
M19.90 Arthrosis, unspecified (Multiple sites)	0.843	0.157
D27 Benign neoplasm of ovary	0.842	0.158
H40.0 Glaucoma suspect	0.842	0.158
Z85.5 Personal history of malignant neoplasm of urinary tract	0.840	0.160
M13.9 Arthritis, unspecified	0.840	0.160
M70-M79 Other soft tissue disorders	0.840	0.160
C64-C68 Malignant neoplasms of urinary tract	0.834	0.166
E05 Thyrotoxicosis [hyperthyroidism]	0.834	0.166
K22.1 Ulcer of oesophagus	0.830	0.170
D32 Benign neoplasm of meninges	0.829	0.171
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.829	0.171
E78.0 Pure hypercholesterolaemia	0.828	0.172
I20 Angina pectoris	0.828	0.172
K22.7 Barrett's oesophagus	0.827	0.173
K05 Gingivitis and periodontal diseases	0.827	0.173
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.825	0.175
I24.9 Acute ischaemic heart disease, unspecified	0.822	0.178
Z11 Special screening examination for infectious and parasitic diseases	0.821	0.179
N20.1 Calculus of ureter	0.821	0.179
N10-N16 Renal tubulo-interstitial diseases	0.819	0.181
E50-E64 Other nutritional deficiencies	0.816	0.184
C43 Malignant melanoma of skin	0.813	0.187
L92 Granulomatous disorders of skin and subcutaneous tissue	0.811	0.189
I24.8 Other forms of acute ischaemic heart disease	0.810	0.190
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms	0.810	0.190
E87 Other disorders of fluid, electrolyte and acid-base balance	0.809	0.191
L98.9 Disorder of skin and subcutaneous tissue, unspecified	0.806	0.194
D18.0 Haemangioma, any site	0.805	0.195
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.805	0.195
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.804	0.196
Z94 Transplanted organ and tissue status	0.803	0.197
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.801	0.199
C92 Myeloid leukaemia	0.801	0.199
H40.1 Primary open-angle glaucoma	0.798	0.202
K26.5 Chronic or unspecified with perforation	0.798	0.202
N18 Chronic renal failure	0.798	0.202
M18 Arthrosis of first carpometacarpal joint	0.797	0.203
L98.8 Other specified disorders of skin and subcutaneous tissue	0.795	0.205
K06 Other disorders of gingiva and edentulous alveolar ridge	0.794	0.206
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.793	0.207
S90-S99 Injuries to the ankle and foot	0.793	0.207
Chapter XXII Codes for special purposes	0.792	0.208
Z40-Z54 Persons encountering health services for specific procedures and health care	0.790	0.210
L03.3 Cellulitis of trunk	0.789	0.211
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.789	0.211
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.788	0.212
F30-F39 Mood [affective] disorders	0.788	0.212
M19.1 Posttraumatic arthrosis of other joints	0.787	0.213
N70-N77 Inflammatory diseases of female pelvic organs	0.787	0.213
D35 Benign neoplasm of other and unspecified endocrine glands	0.787	0.213
E21.3 Hyperparathyroidism, unspecified	0.785	0.215
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.785	0.215
E78.5 Hyperlipidaemia, unspecified	0.785	0.215
N25-N29 Other disorders of kidney and ureter	0.783	0.217
Z89 Acquired absence of limb	0.782	0.218
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.781	0.218
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.781	0.219
K51 Ulcerative colitis	0.779	0.221
C44.6 Skin of upper limb, including shoulder	0.778	0.221
S66 Injury of muscle and tendon at wrist and hand level	0.777	0.223
S61.8 Open wound of other parts of wrist and hand	0.777	0.223
I71 Aortic aneurysm and dissection	0.775	0.225
M47 Spondylosis	0.775	0.225
K04.8 Radicular cyst	0.774	0.226
W00-W19 Falls	0.772	0.228
N00-N08 Glomerular diseases	0.772	0.228
L03.1 Cellulitis of other parts of limb	0.771	0.229
D10 Benign neoplasm of mouth and pharynx	0.770	0.230
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.770	0.230
M19.91 Arthrosis, unspecified (Shoulder region)	0.769	0.231
M19.96 Arthrosis, unspecified-Lower leg	0.768	0.232
M10 Gout	0.767	0.233
W20-W49 Exposure to inanimate mechanical forces	0.767	0.233
N20.9 Urinary calculus, unspecified	0.766	0.234
M19.98 Arthrosis, unspecified (Other)	0.766	0.234
T66-T78 Other and unspecified effects of external causes	0.766	0.234
L40 Psoriasis	0.762	0.238
D11 Benign neoplasm of major salivary glands	0.761	0.239
D24 Benign neoplasm of breast	0.761	0.239
D23.4 Skin of scalp and neck	0.760	0.239
C44.5 Skin of trunk	0.760	0.240
I25.8 Other forms of chronic ischaemic heart disease	0.760	0.240
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances	0.755	0.245
Z95.8 Presence of other cardiac and vascular implants and grafts	0.754	0.246
M80-M85 Disorders of bone density and structure	0.754	0.246
M75 Shoulder lesions	0.753	0.247
K07.3 Anomalies of tooth position	0.753	0.247
C67 Malignant neoplasm of bladder	0.753	0.247
M13.97 Arthritis, unspecified (Ankle and foot)	0.752	0.248
E29 Testicular dysfunction	0.751	0.249
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.750	0.250
D22.5 Melanocytic naevi of trunk	0.750	0.250
E06 Thyroiditis	0.748	0.252
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm	0.748	0.252
K11 Diseases of salivary glands	0.747	0.253
L90 Atrophic disorders of skin	0.747	0.253
Z91 Personal history of risk-factors, not elsewhere classified	0.746	0.254
D12.7 Rectosigmoid junction	0.746	0.254
M19.07 Primary arthrosis of other joints (Ankle and foot)	0.746	0.254
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.746	0.254
Z13.9 Special screening examination, unspecified	0.745	0.255
H40.9 Glaucoma, unspecified	0.745	0.255
L89 Decubitus ulcer	0.744	0.255
K14 Diseases of tongue	0.744	0.256
M07 Psoriatic and enteropathic arthropathies	0.744	0.256
M75.1 Rotator cuff syndrome	0.743	0.257
K04.7 Periapical abscess without sinus	0.743	0.257
L43 Lichen planus	0.742	0.258
S70-S79 Injuries to the hip and thigh	0.742	0.258
M00-M03 Infectious arthropathies	0.741	0.258
M11 Other crystal arthropathies	0.739	0.261
E28 Ovarian dysfunction	0.738	0.262
M86-M90 Other osteopathies	0.738	0.262
C15-C26 Malignant neoplasms of digestive organs	0.738	0.262
Z93.2 Ileostomy status	0.736	0.264
S01 Open wound of head	0.736	0.264
Z47 Other orthopaedic follow-up care	0.735	0.265
M19.09 Primary arthrosis of other joints (Site unspecified)	0.735	0.265
F40-F48 Neurotic, stress-related and somatoform disorders	0.735	0.265
M05 Seropositive rheumatoid arthritis	0.735	0.265
K27 Peptic ulcer, site unspecified	0.734	0.266
Y57 Other and unspecified drugs and medicaments	0.733	0.267
S68 Traumatic amputation of wrist and hand	0.732	0.268
Z42 Follow-up care involving plastic surgery	0.731	0.269
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.730	0.270
S40-S49 Injuries to the shoulder and upper arm	0.730	0.270
H10-H13 Disorders of conjunctiva	0.729	0.271
D22.4 Melanocytic naevi of scalp and neck	0.728	0.272
Z85.6 Personal history of leukaemia	0.727	0.272
C44.2 Skin of ear and external auricular canal	0.727	0.273
D22.1 Melanocytic naevi of eyelid, including canthus	0.726	0.273
C44.0 Skin of lip	0.725	0.274
I95-I99 Other and unspecified disorders of the circulatory system	0.722	0.278
E05.9 Thyrotoxicosis, unspecified	0.721	0.279
Z93.3 Colostomy status	0.720	0.280
L03.2 Cellulitis of face	0.719	0.281
H46-H48 Disorders of optic nerve and visual pathways	0.719	0.281
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.718	0.282
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm	0.718	0.282
I10-I15 Hypertensive diseases	0.718	0.282
S67 Crushing injury of wrist and hand	0.717	0.283
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.717	0.283
C40-C41 Malignant neoplasms of bone and articular cartilage	0.717	0.283
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
E40-E46 Malnutrition	0.717	0.283
C44.9 Malignant neoplasm of skin, unspecified	0.717	0.283
C44.8 Overlapping lesion of skin	0.717	0.283
D21 Other benign neoplasms of connective and other soft tissue	0.716	0.283
D12.8 Rectum	0.716	0.284
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.716	0.284
E00 Congenital iodine-deficiency syndrome	0.716	0.284
E02 Subclinical iodine-deficiency hypothyroidism	0.716	0.284
Chapter VI Diseases of the nervous system	0.716	0.284
Z31 Procreative management	0.716	0.284
T79-T79 Certain early complications of trauma	0.716	0.284
T33-T35 Frostbite	0.716	0.284
T26-T28 Burns and corrosions confined to eye and internal organs	0.716	0.284
T20-T25 Burns and corrosions of external body surface, specified by site	0.716	0.284
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.716	0.284
T00-T07 Injuries involving multiple body regions	0.716	0.284
S10-S19 Injuries to the neck	0.716	0.284
E03.8 Other specified hypothyroidism	0.716	0.284
E03.5 Myxoedema coma	0.716	0.284
E03.4 Atrophy of thyroid (acquired)	0.716	0.284
E03.3 Postinfectious hypothyroidism	0.716	0.284
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.716	0.284
E03.1 Congenital hypothyroidism without goitre	0.716	0.284
E03.0 Congenital hypothyroidism with diffuse goitre	0.716	0.284
D31 Benign neoplasm of eye and adnexa	0.716	0.284
D30 Benign neoplasm of urinary organs	0.716	0.284
D29 Benign neoplasm of male genital organs	0.716	0.284
D28 Benign neoplasm of other and unspecified female genital organs	0.716	0.284
D26 Other benign neoplasms of uterus	0.716	0.284
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.716	0.284
D19 Benign neoplasm of mesothelial tissue	0.716	0.284
D16 Benign neoplasm of bone and articular cartilage	0.716	0.284
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.716	0.284
D14 Benign neoplasm of middle ear and respiratory system	0.716	0.284
M46 Other inflammatory spondylopathies	0.716	0.284
S22 Fracture of rib(s), sternum and thoracic spine	0.715	0.285
M91-M94 Chondropathies	0.715	0.285
M60-M63 Disorders of muscles	0.715	0.285
D22.7 Melanocytic naevi of lower limb, including hip	0.714	0.286
X20-X29 Contact with venomous animals and plants	0.712	0.288
K28 Gastrojejunal ulcer	0.712	0.288
K23 Disorders of oesophagus in diseases classified elsewhere	0.712	0.288
I60-I69 Cerebrovascular diseases	0.712	0.288
F99-F99 Unspecified mental disorder	0.711	0.289
L10-L14 Bullous disorders	0.711	0.289
D41.4 Bladder	0.711	0.289
E27 Other disorders of adrenal gland	0.710	0.289
I05-I09 Chronic rheumatic heart diseases	0.710	0.290
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.710	0.290
L50-L54 Urticaria and erythema	0.710	0.290
N22 Calculus of urinary tract in diseases classified elsewhere	0.710	0.290
S52 Fracture of forearm	0.708	0.292
D32.0 Cerebral meninges	0.708	0.292
M13.0 Polyarthritis, unspecified	0.708	0.292
H53-H54 Visual disturbances and blindness	0.707	0.293
I20.0 Unstable angina	0.707	0.293
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.706	0.293
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.705	0.295
Z30 Contraceptive management	0.702	0.298
S69 Other and unspecified injuries of wrist and hand	0.702	0.298
S65 Injury of blood vessels at wrist and hand level	0.702	0.298
S60 Superficial injury of wrist and hand	0.702	0.298
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.701	0.299
M13.96 Arthritis, unspecified (Lower leg)	0.701	0.299
T15-T19 Effects of foreign body entering through natural orifice	0.700	0.300
M19.94 Arthrosis, unspecified (Hand)	0.700	0.300
K12 Stomatitis and related lesions	0.700	0.300
F80-F89 Disorders of psychological development	0.700	0.300
D33 Benign neoplasm of brain and other parts of central nervous system	0.699	0.300
I00-I02 Acute rheumatic fever	0.699	0.301
Z84 Family history of other conditions	0.699	0.301
Z81 Family history of mental and behavioural disorders	0.699	0.301
C43.7 Malignant melanoma of lower limb, including hip	0.699	0.301
Z92 Personal history of medical treatment	0.698	0.302
K04.6 Periapical abscess with sinus	0.697	0.303
M15 Polyarthrosis	0.697	0.303
Chapter X Diseases of the respiratory system	0.695	0.305
L03.8 Cellulitis of other sites	0.695	0.305
I22 Subsequent myocardial infarction	0.695	0.305
T85 Complications of other internal prosthetic devices, implants and grafts	0.694	0.306
K10 Other diseases of jaws	0.694	0.306
K09 Cysts of oral region, not elsewhere classified	0.694	0.306
K03 Other diseases of hard tissues of teeth	0.694	0.306
K00 Disorders of tooth development and eruption	0.694	0.306
I25.5 Ischaemic cardiomyopathy	0.694	0.306
M19.8 Other specified arthrosis	0.694	0.306
M19.2 Other secondary arthrosis	0.694	0.306
V80-V89 Other land transport accidents	0.693	0.307
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.693	0.307
I23 Certain current complications following acute myocardial infarction	0.693	0.307
S05 Injury of eye and orbit	0.693	0.307
D23.6 Skin of upper limb, including shoulder	0.692	0.308
S64 Injury of nerves at wrist and hand level	0.692	0.308
Z13.3 Special screening examination for mental and behavioural disorders	0.692	0.308
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device	0.692	0.308
Z41 Procedures for purposes other than remedying health state	0.691	0.309
S62 Fracture at wrist and hand level	0.690	0.309
Z11.2 Special screening examination for other bacterial diseases	0.690	0.310
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere	0.689	0.310
L95 Vasculitis limited to skin, not elsewhere classified	0.689	0.310
L94 Other localised connective tissue disorders	0.689	0.310
L93 Lupus erythematosus	0.689	0.310
L87 Transepidermal elimination disorders	0.689	0.310
L88 Pyoderma gangrenosum	0.689	0.310
L86 Keratoderma in diseases classified elsewhere	0.689	0.310
L83 Acanthosis nigricans	0.689	0.310
L80 Vitiligo	0.689	0.310
K26.6 Chronic or unspecified with both haemorrhage and perforation	0.689	0.311
K26.2 Acute with both haemorrhage and perforation	0.689	0.311
K26.1 Acute with perforation	0.689	0.311
K26.0 Acute with haemorrhage	0.689	0.311
Z09.0 Follow-up examination after surgery for other conditions	0.689	0.311
D36 Benign neoplasm of other and unspecified sites	0.689	0.311
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.689	0.311
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.688	0.312
E87.2 Acidosis	0.688	0.312
K04.9 Other and unspecified diseases of pulp and periapical tissues	0.688	0.312
K22.2 Oesophageal obstruction	0.688	0.312
D23.7 Skin of lower limb, including hip	0.688	0.312
M14 Arthropathies in other diseases classified elsewhere	0.687	0.313
M12 Other specific arthropathies	0.687	0.313
M09 Juvenile arthritis in diseases classified elsewhere	0.687	0.313
M08 Juvenile arthritis	0.687	0.313
M13.99 Arthritis, unspecified (Site unspecified)	0.687	0.313
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.686	0.314
N99-N99 Other disorders of the genitourinary system	0.685	0.315
Z10 Routine general health check-up of defined subpopulation	0.685	0.315
M19.95 Arthrosis, unspecified (Pelvic region and thigh)	0.684	0.316
M19.92 Arthrosis, unspecified (Upper arm)	0.684	0.316
E88 Other metabolic disorders	0.683	0.317
K05.1 Chronic gingivitis	0.683	0.317
N17 Acute renal failure	0.683	0.317
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.682	0.318
S61.1 Open wound of finger(s) with damage to nail	0.681	0.318
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.681	0.318
I77 Other disorders of arteries and arterioles	0.680	0.320
C44.7 Skin of lower limb, including hip	0.680	0.320
K51.8 Other ulcerative colitis	0.680	0.320
C92.0 Acute myeloid leukaemia	0.679	0.321
D23.5 Skin of trunk	0.679	0.321
Z88.7 Personal history of allergy to serum and vaccine	0.679	0.321
Z94.0 Kidney transplant status	0.679	0.321
J30-J39 Other diseases of upper respiratory tract	0.678	0.322
S61.7 Multiple open wounds of wrist and hand	0.678	0.322
C92.1 Chronic myeloid leukaemia	0.677	0.323
E86 Volume depletion	0.677	0.323
H55-H59 Other disorders of eye and adnexa	0.677	0.323
S02 Fracture of skull and facial bones	0.676	0.324
E85 Amyloidosis	0.676	0.324
E84 Cystic fibrosis	0.676	0.324
E79 Disorders of purine and pyrimidine metabolism	0.676	0.324
E77 Disorders of glycoprotein metabolism	0.676	0.324
E76 Disorders of glycosaminoglycan metabolism	0.676	0.324
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.676	0.324
E74 Other disorders of carbohydrate metabolism	0.676	0.324
E73 Lactose intolerance	0.676	0.324
E72 Other disorders of amino-acid metabolism	0.676	0.324
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.676	0.324
E70 Disorders of aromatic amino-acid metabolism	0.676	0.324
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.676	0.324
D12.5 Sigmoid colon	0.676	0.324
E35 Disorders of endocrine glands in diseases classified elsewhere	0.675	0.325
E34 Other endocrine disorders	0.675	0.325
E32 Diseases of thymus	0.675	0.325
E31 Polyglandular dysfunction	0.675	0.325
E30 Disorders of puberty, not elsewhere classified	0.675	0.325
E26 Hyperaldosteronism	0.675	0.325
E25 Adrenogenital disorders	0.675	0.325
E24 Cushing's syndrome	0.675	0.325
E22 Hyperfunction of pituitary gland	0.675	0.325
E20 Hypoparathyroidism	0.675	0.325
N21 Calculus of lower urinary tract	0.675	0.325
D22.9 Melanocytic naevi, unspecified	0.675	0.325
D22.2 Melanocytic naevi of ear and external auricular canal	0.675	0.325
D22.0 Melanocytic naevi of lip	0.675	0.325
I20.9 Angina pectoris, unspecified	0.674	0.326
Z09.8 Follow-up examination after other treatment for other conditions	0.673	0.327
M13.90 Arthritis, unspecified (Multiple sites)	0.673	0.327
K26.3 Acute without haemorrhage or perforation	0.673	0.327
Z30.5 Surveillance of (intra-uterine) contraceptive device	0.673	0.327
Z08.1 Follow-up examination after radiotherapy for malignant neoplasm	0.672	0.328
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.671	0.329
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified	0.671	0.329
D34 Benign neoplasm of thyroid gland	0.669	0.331
E23 Hypofunction and other disorders of pituitary gland	0.669	0.331
K06.8 Other specified disorders of gingiva and edentulous alveolar ridge	0.669	0.331
K26.4 Chronic or unspecified with haemorrhage	0.669	0.331
K07.6 Temporomandibular joint disorders	0.668	0.332
D23.9 Skin, unspecified	0.668	0.332
D23.2 Skin of ear and external auricular canal	0.668	0.332
D23.0 Skin of lip	0.668	0.332
V10-V19 Pedal cyclist injured in transport accident	0.668	0.332
Z97 Presence of other devices	0.666	0.333
L81 Other disorders of pigmentation	0.666	0.333
C85.1 B-cell lymphoma, unspecified	0.666	0.334
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.666	0.334
Y35-Y36 Legal intervention and operations of war	0.666	0.334
Y10-Y34 Event of undetermined intent	0.666	0.334
Y00-Y09 Assault	0.666	0.334
X85-X99 Assault	0.666	0.334
X58-X59 Accidental exposure to other and unspecified factors	0.666	0.334
X50-X57 Overexertion, travel and privation	0.666	0.334
X40-X49 Accidental poisoning by and exposure to noxious substances	0.666	0.334
X30-X39 Exposure to forces of nature	0.666	0.334
X10-X19 Contact with heat and hot substances	0.666	0.334
X00-X09 Exposure to smoke, fire and flames	0.666	0.334
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.666	0.334
W75-W84 Other accidental threats to breathing	0.666	0.334
W65-W74 Accidental drowning and submersion	0.666	0.334
W50-W64 Exposure to animate mechanical forces	0.666	0.334
V98-V99 Other and unspecified transport accidents	0.666	0.334
V95-V97 Air and space transport accidents	0.666	0.334
V90-V94 Water transport accidents	0.666	0.334
V70-V79 Bus occupant injured in transport accident	0.666	0.334
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.666	0.334
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.666	0.334
V40-V49 Car occupant injured in transport accident	0.666	0.334
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.666	0.334
V01-V09 Pedestrian injured in transport accident	0.666	0.334
D12.0 Caecum	0.665	0.335
Z95.3 Presence of xenogenic heart valve	0.664	0.335
I25.6 Silent myocardial ischaemia	0.664	0.336
I25.4 Coronary artery aneurysm	0.664	0.336
I25.3 Aneurysm of heart	0.664	0.336
I25.0 Atherosclerotic cardiovascular disease, so described	0.664	0.336
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.664	0.336
Z88.4 Personal history of allergy to anaesthetic agent	0.663	0.337
D48.1 Connective and other soft tissue	0.663	0.337
K05.3 Chronic periodontitis	0.662	0.338
D12.9 Anus and anal canal	0.661	0.339
D12.1 Appendix	0.661	0.339
Z32 Pregnancy examination and test	0.661	0.339
E83 Disorders of mineral metabolism	0.661	0.339
M13.91 Arthritis, unspecified (Shoulder region)	0.660	0.340
Z85.0 Personal history of malignant neoplasm of digestive organs	0.660	0.340
Z85.9 Personal history of malignant neoplasm, unspecified	0.660	0.340
E87.6 Hypokalaemia	0.660	0.340
C67.9 Bladder, unspecified	0.660	0.340
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.659	0.341
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.659	0.341
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.659	0.341
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.659	0.341
L04 Acute lymphadenitis	0.659	0.341
L01 Impetigo	0.659	0.341
L00 Staphylococcal scalded skin syndrome	0.659	0.341
Z08.8 Follow-up examination after other treatment for malignant neoplasm	0.659	0.341
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.658	0.342
K01 Embedded and impacted teeth	0.658	0.342
M19.17 Post-traumatic arthrosis of other joints (Ankle and foot)	0.658	0.342
D12.2 Ascending colon	0.658	0.342
F60-F69 Disorders of adult personality and behaviour	0.657	0.343
S61.9 Open wound of wrist and hand, part unspecified	0.657	0.343
T92 Sequelae of injuries of upper limb	0.657	0.343
L90.5 Scar conditions and fibrosis of skin	0.657	0.343
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.656	0.344
I24.1 Dressler's syndrome	0.655	0.344
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.655	0.344
F41 Other anxiety disorders	0.655	0.345
I72 Other aneurysm	0.654	0.345
S80-S89 Injuries to the knee and lower leg	0.654	0.346

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations