TreeWAS – Variant ID: rs2523733

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
L40.9 Psoriasis, unspecified	1.000	0.000	0.000
L40.5 Arthropathic psoriasis	1.000	0.000	0.000
L40 Psoriasis	1.000	0.000	0.000
M06.9 Rheumatoid arthritis, unspecified	0.000	0.003	0.997
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.004	0.996
E03.9 Hypothyroidism, unspecified	0.000	0.004	0.996
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.008	0.992
E10 Insulin-dependent diabetes mellitus	0.000	0.009	0.991
E10.9 Without complications	0.000	0.010	0.990
E03 Other hypothyroidism	0.000	0.020	0.980
E00-E07 Disorders of thyroid gland	0.000	0.029	0.971
E10.3 With ophthalmic complications	0.000	0.040	0.960
E10-E14 Diabetes mellitus	0.000	0.042	0.958
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.044	0.956
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.062	0.938
E10.1 With ketoacidosis	0.000	0.084	0.916
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.000	0.084	0.916
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.089	0.911
L40.8 Other psoriasis	0.893	0.107	0.000
E04 Other non-toxic goitre	0.000	0.119	0.881
E10.4 With neurological complications	0.000	0.161	0.839
E04.2 Non-toxic multinodular goitre	0.000	0.170	0.830
E06 Thyroiditis	0.000	0.171	0.829
E50-E64 Other nutritional deficiencies	0.000	0.176	0.824
L40.0 Psoriasis vulgaris	0.822	0.178	0.000
E10.2 With renal complications	0.000	0.183	0.817
M07.3 Other psoriatic arthropathies	0.802	0.197	0.001
M07.30 Other psoriatic arthropathies (Multiple sites)	0.796	0.204	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.793	0.207	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.214	0.785
E10.8 With unspecified complications	0.000	0.224	0.776
E53 Deficiency of other B group vitamins	0.000	0.230	0.769
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.000	0.232	0.768
E10.5 With peripheral circulatory complications	0.000	0.238	0.762
M07 Psoriatic and enteropathic arthropathies	0.738	0.241	0.022
E06.3 Autoimmune thyroiditis	0.000	0.249	0.751
M05-M14 Inflammatory polyarthropathies	0.692	0.258	0.050
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.263	0.737
E53.8 Deficiency of other specified B group vitamins	0.000	0.269	0.731
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.000	0.281	0.719
L40.4 Guttate psoriasis	0.717	0.283	0.000
L40.3 Pustulosis palmaris et plantaris	0.717	0.283	0.000
L40.2 Acrodermatitis continua	0.717	0.283	0.000
L40.1 Generalised pustular psoriasis	0.717	0.283	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.000	0.285	0.715
E10.7 With multiple complications	0.000	0.289	0.711
E10.0 With coma	0.000	0.291	0.709
E03.5 Myxoedema coma	0.000	0.297	0.703
E03.4 Atrophy of thyroid (acquired)	0.000	0.297	0.703
E03.3 Postinfectious hypothyroidism	0.000	0.297	0.703
E03.1 Congenital hypothyroidism without goitre	0.000	0.297	0.703
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.297	0.703
E04.0 Non-toxic diffuse goitre	0.000	0.298	0.702
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.304	0.696
E00 Congenital iodine-deficiency syndrome	0.000	0.304	0.696
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.304	0.696
E03.8 Other specified hypothyroidism	0.000	0.310	0.690
E12 Malnutrition-related diabetes mellitus	0.000	0.313	0.687
E40-E46 Malnutrition	0.000	0.314	0.686
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.682	0.317	0.000
E10.6 With other specified complications	0.000	0.322	0.678
M47.8 Other spondylosis	0.671	0.329	0.000
M45-M49 Spondylopathies	0.669	0.331	0.000
M47 Spondylosis	0.668	0.332	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.666	0.333	0.001
M47.82 Other spondylosis (Cervical region)	0.662	0.338	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.345	0.654
E07 Other disorders of thyroid	0.000	0.348	0.652
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.644	0.356	0.001
M47.80 Other spondylosis (Multiple sites in spine)	0.644	0.356	0.000
M10 Gout	0.623	0.358	0.020
E04.8 Other specified non-toxic goitre	0.000	0.368	0.632
E65-E68 Obesity and other hyperalimentation	0.000	0.371	0.629
M07.36 Other psoriatic arthropathies (Lower leg)	0.627	0.372	0.001
M06 Other rheumatoid arthritis	0.272	0.373	0.355
M86-M90 Other osteopathies	0.618	0.382	0.000
E20-E35 Disorders of other endocrine glands	0.000	0.387	0.613
M91-M94 Chondropathies	0.610	0.390	0.000
M40-M43 Deforming dorsopathies	0.606	0.394	0.000
E13 Other specified diabetes mellitus	0.000	0.403	0.597
E06.5 Other chronic thyroiditis	0.000	0.406	0.594
E06.4 Drug-induced thyroiditis	0.000	0.406	0.594
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.406	0.594
E06.1 Subacute thyroiditis	0.000	0.406	0.594
E06.0 Acute thyroiditis	0.000	0.406	0.594
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.409	0.591
E63 Other nutritional deficiencies	0.000	0.409	0.591
E56 Other vitamin deficiencies	0.000	0.409	0.591
E51 Thiamine deficiency	0.000	0.409	0.591
E50 Vitamin A deficiency	0.000	0.409	0.591
E60 Dietary zinc deficiency	0.000	0.409	0.591
E59 Dietary selenium deficiency	0.000	0.409	0.591
E58 Dietary calcium deficiency	0.000	0.409	0.591
E54 Ascorbic acid deficiency	0.000	0.409	0.591
E52 Niacin deficiency [pellagra]	0.000	0.409	0.591
M80-M85 Disorders of bone density and structure	0.588	0.412	0.000
M50-M54 Other dorsopathies	0.587	0.413	0.000
E27 Other disorders of adrenal gland	0.000	0.421	0.579
M47.89 Other spondylosis (Site unspecified)	0.577	0.423	0.000
M07.38 Other psoriatic arthropathies (Other)	0.575	0.424	0.001
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.575	0.424	0.001
M07.33 Other psoriatic arthropathies (Forearm)	0.575	0.424	0.001
M07.32 Other psoriatic arthropathies (Upper arm)	0.575	0.424	0.001
M07.31 Other psoriatic arthropathies (Shoulder region)	0.575	0.424	0.001
M47.9 Spondylosis, unspecified	0.575	0.425	0.000
E27.1 Primary adrenocortical insufficiency	0.000	0.432	0.568
M70-M79 Other soft tissue disorders	0.564	0.436	0.000
M10.9 Gout, unspecified	0.561	0.437	0.002
E04.9 Non-toxic goitre, unspecified	0.000	0.446	0.554
E04.1 Non-toxic single thyroid nodule	0.000	0.447	0.553
E53.9 Vitamin B deficiency, unspecified	0.000	0.448	0.552
E53.1 Pyridoxine deficiency	0.000	0.448	0.552
E53.0 Riboflavin deficiency	0.000	0.448	0.552
M87 Osteonecrosis	0.551	0.449	0.000
M50 Cervical disk disorders	0.548	0.452	0.000
E61 Deficiency of other nutrient elements	0.000	0.452	0.548
M07.6 Other enteropathic arthropathies	0.529	0.456	0.016
M07.5 Arthropathy in ulcerative colitis	0.529	0.456	0.016
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.529	0.456	0.016
M07.2 Psoriatic spondylitis	0.529	0.456	0.016
M07.1 Arthritis mutilans	0.529	0.456	0.016
M07.0 Distal interphalangeal psoriatic arthropathy	0.529	0.456	0.016
M49 Spondylopathies in diseases classified elsewhere	0.543	0.457	0.000
M50.3 Other cervical disk degeneration	0.540	0.460	0.000
M89 Other disorders of bone	0.538	0.462	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.468	0.532
M12 Other specific arthropathies	0.496	0.468	0.036
M09 Juvenile arthritis in diseases classified elsewhere	0.496	0.468	0.036
M08 Juvenile arthritis	0.496	0.468	0.036
M94 Other disorders of cartilage	0.532	0.468	0.000
M43 Other deforming dorsopathies	0.530	0.470	0.000
M47.83 Other spondylosis (Cervicothoracic region)	0.525	0.475	0.000
M47.99 Spondylosis, unspecified (Site unspecified)	0.525	0.475	0.000
E06.9 Thyroiditis, unspecified	0.000	0.480	0.520
M92 Other juvenile osteochondrosis	0.520	0.480	0.000
M77 Other enthesopathies	0.517	0.483	0.000
M47.84 Other spondylosis (Thoracic region)	0.515	0.485	0.000
M85 Other disorders of bone density and structure	0.513	0.487	0.000
M47.85 Other spondylosis (Thoracolumbar region)	0.501	0.499	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.501	0.499
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.501	0.499
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.501	0.499
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.501	0.499
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.501	0.499
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.501	0.499
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.501	0.499
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.501	0.499
M53 Other dorsopathies, not elsewhere classified	0.498	0.502	0.000
M71 Other bursopathies	0.497	0.503	0.000
M10.0 Idiopathic gout	0.481	0.506	0.013
E12.9 Without complications	0.000	0.507	0.493
E12.8 With unspecified complications	0.000	0.507	0.493
E12.7 With multiple complications	0.000	0.507	0.493
E12.6 With other specified complications	0.000	0.507	0.493
E12.5 With peripheral circulatory complications	0.000	0.507	0.493
E12.4 With neurological complications	0.000	0.507	0.493
E12.3 With ophthalmic complications	0.000	0.507	0.493
E12.2 With renal complications	0.000	0.507	0.493
E12.1 With ketoacidosis	0.000	0.507	0.493
E12.0 With coma	0.000	0.507	0.493
E46 Unspecified protein-energy malnutrition	0.000	0.508	0.492
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.508	0.492
E45 Retarded development following protein-energy malnutrition	0.000	0.508	0.492
E43 Unspecified severe protein-energy malnutrition	0.000	0.508	0.492
E42 Marasmic kwashiorkor	0.000	0.508	0.492
E41 Nutritional marasmus	0.000	0.508	0.492
E40 Kwashiorkor	0.000	0.508	0.492
M60-M63 Disorders of muscles	0.488	0.511	0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)	0.488	0.512	0.000
E24 Cushing's syndrome	0.000	0.512	0.488
M40 Kyphosis and lordosis	0.487	0.513	0.000
E07.8 Other specified disorders of thyroid	0.000	0.515	0.485
M77.4 Metatarsalgia	0.483	0.517	0.000
M84 Disorders of continuity of bone	0.483	0.517	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.482	0.518	0.000
E55 Vitamin D deficiency	0.000	0.518	0.482
M47.81 Other spondylosis (Occipito-atlanto-axial region)	0.481	0.519	0.000
M47.0 Anterior spinal and vertebral artery compression syndromes	0.479	0.521	0.000
M47.94 Spondylosis, unspecified (Thoracic region)	0.476	0.524	0.000
M94.8 Other specified disorders of cartilage	0.476	0.524	0.000
M89.0 Algoneurodystrophy	0.474	0.526	0.000
M14 Arthropathies in other diseases classified elsewhere	0.435	0.526	0.039
E65 Localised adiposity	0.000	0.526	0.474
M00-M03 Infectious arthropathies	0.471	0.528	0.000
M89.9 Disorder of bone, unspecified	0.469	0.531	0.000
E07.1 Dyshormogenetic goitre	0.000	0.532	0.468
E07.0 Hypersecretion of calcitonin	0.000	0.532	0.468
M43.1 Spondylolisthesis	0.468	0.532	0.000
M10.90 Gout, unspecified (Multiple sites)	0.463	0.536	0.001
M11 Other crystal arthropathies	0.426	0.537	0.037
M87.2 Osteonecrosis due to previous trauma	0.462	0.538	0.000
M10.4 Other secondary gout	0.446	0.539	0.014
M10.3 Gout due to impairment of renal function	0.446	0.539	0.014
M10.2 Drug-induced gout	0.446	0.539	0.014
M10.1 Lead-induced gout	0.446	0.539	0.014
M46 Other inflammatory spondylopathies	0.460	0.540	0.000
M77.47 Metatarsalgia-Ankle/Foot	0.460	0.540	0.000
E22 Hyperfunction of pituitary gland	0.000	0.540	0.460
M87.9 Osteonecrosis, unspecified	0.457	0.543	0.000
M10.97 Gout, unspecified (Ankle and foot)	0.456	0.544	0.001
M92.6 Juvenile osteochondrosis of tarsus	0.455	0.545	0.000
M49.5 Collapsed vertebra in diseases classified elsewhere	0.453	0.547	0.000
M91 Juvenile osteochondrosis of hip and pelvis	0.452	0.548	0.000
E67 Other hyperalimentation	0.000	0.549	0.451
E68 Sequelae of hyperalimentation	0.000	0.549	0.451
M88 Paget's disease of bone [osteitis deformans]	0.450	0.550	0.000
M06.8 Other specified rheumatoid arthritis	0.195	0.550	0.255
M06.2 Rheumatoid bursitis	0.195	0.550	0.255
M06.1 Adult-onset Still's disease	0.195	0.550	0.255
E14 Unspecified diabetes mellitus	0.000	0.552	0.448
E27.2 Addisonian crisis	0.000	0.552	0.448
M85.6 Other cyst of bone	0.445	0.555	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.560	0.440
E32 Diseases of thymus	0.000	0.560	0.440
E31 Polyglandular dysfunction	0.000	0.560	0.440
E30 Disorders of puberty, not elsewhere classified	0.000	0.560	0.440
E25 Adrenogenital disorders	0.000	0.560	0.440
M43.17 Spondylolisthesis (Lumbosacral region)	0.437	0.563	0.000
M90 Osteopathies in diseases classified elsewhere	0.435	0.565	0.000
M42 Spinal osteochondrosis	0.434	0.566	0.000
M10.96 Gout, unspecified (Lower leg)	0.431	0.568	0.001
E13.8 With unspecified complications	0.000	0.572	0.428
E13.7 With multiple complications	0.000	0.572	0.428
E13.6 With other specified complications	0.000	0.572	0.428
E13.5 With peripheral circulatory complications	0.000	0.572	0.428
E13.4 With neurological complications	0.000	0.572	0.428
E13.3 With ophthalmic complications	0.000	0.572	0.428
E13.2 With renal complications	0.000	0.572	0.428
E13.1 With ketoacidosis	0.000	0.572	0.428
E13.0 With coma	0.000	0.572	0.428
E20 Hypoparathyroidism	0.000	0.572	0.428
M76 Enthesopathies of lower limb, excluding foot	0.427	0.573	0.000
M47.1 Other spondylosis with myelopathy	0.426	0.574	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.575	0.425
M41 Scoliosis	0.425	0.575	0.000
M06.3 Rheumatoid nodule	0.174	0.576	0.250
E50.9 Vitamin A deficiency, unspecified	0.000	0.576	0.424
E50.8 Other manifestations of vitamin A deficiency	0.000	0.576	0.424
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.576	0.424
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.576	0.424
E50.5 Vitamin A deficiency with night blindness	0.000	0.576	0.424
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.576	0.424
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.576	0.424
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.576	0.424
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.576	0.424
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.576	0.424
E51.9 Thiamine deficiency, unspecified	0.000	0.576	0.424
E51.8 Other manifestations of thiamine deficiency	0.000	0.576	0.424
E51.2 Wernicke's encephalopathy	0.000	0.576	0.424
E51.1 Beriberi	0.000	0.576	0.424
E56.9 Vitamin deficiency, unspecified	0.000	0.576	0.424
E56.8 Deficiency of other vitamins	0.000	0.576	0.424
E56.1 Deficiency of vitamin K	0.000	0.576	0.424
E56.0 Deficiency of vitamin E	0.000	0.576	0.424
E63.9 Nutritional deficiency, unspecified	0.000	0.576	0.424
E63.8 Other specified nutritional deficiencies	0.000	0.576	0.424
E63.1 Imbalance of constituents of food intake	0.000	0.576	0.424
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.576	0.424
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.576	0.424
E64.8 Sequelae of other nutritional deficiencies	0.000	0.576	0.424
E64.3 Sequelae of rickets	0.000	0.576	0.424
E64.2 Sequelae of vitamin C deficiency	0.000	0.576	0.424
E64.1 Sequelae of vitamin A deficiency	0.000	0.576	0.424
E64.0 Sequelae of protein-energy malnutrition	0.000	0.576	0.424
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)	0.423	0.577	0.000
M83 Adult osteomalacia	0.421	0.579	0.000
M71.2 Synovial cyst of popliteal space [Baker]	0.421	0.579	0.000
E61.1 Iron deficiency	0.000	0.579	0.421
M06.4 Inflammatory polyarthropathy	0.194	0.579	0.227
M50.2 Other cervical disk displacement	0.420	0.580	0.000
M94.88 Other specified disorders of cartilage (Other)	0.418	0.582	0.000
M77.9 Enthesopathy, unspecified	0.418	0.582	0.000
M10.99 Gout, unspecified (Site unspecified)	0.417	0.583	0.000
M50.8 Other cervical disk disorders	0.417	0.583	0.000
M10.93 Gout, unspecified (Forearm)	0.415	0.583	0.001
E27.5 Adrenomedullary hyperfunction	0.000	0.585	0.415
E27.0 Other adrenocortical overactivity	0.000	0.585	0.415
M51 Other intervertebral disk disorders	0.415	0.585	0.000
M87.8 Other osteonecrosis	0.414	0.586	0.000
M47.95 Spondylosis, unspecified (Thoracolumbar region)	0.412	0.588	0.000
M47.93 Spondylosis, unspecified (Cervicothoracic region)	0.412	0.588	0.000
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)	0.412	0.588	0.000
M43.6 Torticollis	0.410	0.590	0.000
M85.8 Other specified disorders of bone density and structure	0.407	0.593	0.000
E28 Ovarian dysfunction	0.000	0.593	0.407
M71.3 Other bursal cyst	0.407	0.593	0.000
E14.3 With ophthalmic complications	0.000	0.594	0.406
M73 Soft tissue disorders in diseases classified elsewhere	0.405	0.595	0.000
M10.98 Gout, unspecified (Other)	0.402	0.596	0.001
M10.95 Gout, unspecified (Pelvic region and thigh)	0.402	0.596	0.001
M10.94 Gout, unspecified (Hand)	0.402	0.596	0.001
M10.92 Gout, unspecified (Upper arm)	0.402	0.596	0.001
M10.91 Gout, unspecified (Shoulder region)	0.402	0.596	0.001
M82 Osteoporosis in diseases classified elsewhere	0.403	0.597	0.000
M80 Osteoporosis with pathological fracture	0.403	0.597	0.000
M40.2 Other and unspecified kyphosis	0.402	0.597	0.000
M89.3 Hypertrophy of bone	0.400	0.599	0.000
E07.9 Disorder of thyroid, unspecified	0.000	0.600	0.400
M89.07 Algoneurodystrophy (Ankle and foot)	0.400	0.600	0.000
M87.20 Osteonecrosis due to previous trauma (Multiple sites)	0.399	0.601	0.000
E24.9 Cushing's syndrome, unspecified	0.000	0.602	0.398
M05 Seropositive rheumatoid arthritis	0.348	0.602	0.050
M53.8 Other specified dorsopathies	0.397	0.603	0.000
M87.3 Other secondary osteonecrosis	0.395	0.604	0.000
M87.1 Osteonecrosis due to drugs	0.395	0.604	0.000
M87.0 Idiopathic aseptic necrosis of bone	0.395	0.604	0.000
M81 Osteoporosis without pathological fracture	0.394	0.606	0.000
E61.9 Deficiency of nutrient element, unspecified	0.000	0.607	0.393
E61.8 Deficiency of other specified nutrient elements	0.000	0.607	0.393
E61.7 Deficiency of multiple nutrient elements	0.000	0.607	0.393
E61.6 Vanadium deficiency	0.000	0.607	0.393
E61.5 Molybdenum deficiency	0.000	0.607	0.393
E61.4 Chromium deficiency	0.000	0.607	0.393
E61.3 Manganese deficiency	0.000	0.607	0.393
E61.0 Copper deficiency	0.000	0.607	0.393
M94.9 Disorder of cartilage, unspecified	0.391	0.609	0.000
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)	0.379	0.609	0.011
M07.08 Distal interphalangeal proriatic arthropathy-Other	0.379	0.609	0.011
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)	0.379	0.609	0.011
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg	0.379	0.609	0.011
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh	0.379	0.609	0.011
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)	0.379	0.609	0.011
M07.03 Distal interphalangeal proriatic arthropathy-Forearm	0.379	0.609	0.011
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm	0.379	0.609	0.011
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region	0.379	0.609	0.011
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)	0.379	0.609	0.011
M07.19 Arthritis mutilans (Site unspecified)	0.379	0.609	0.011
M07.18 Arthritis mutilans (Other)	0.379	0.609	0.011
M07.17 Arthritis mutilans (Ankle and foot)	0.379	0.609	0.011
M07.16 Arthritis mutilans (Lower leg)	0.379	0.609	0.011
M07.15 Arthritis mutilans (Pelvic region and thigh)	0.379	0.609	0.011
M07.14 Arthritis mutilans (Hand)	0.379	0.609	0.011
M07.13 Arthritis mutilans (Forearm)	0.379	0.609	0.011
M07.12 Arthritis mutilans (Upper arm)	0.379	0.609	0.011
M07.11 Arthritis mutilans (Shoulder region)	0.379	0.609	0.011
M07.10 Arthritis mutilans (Multiple sites)	0.379	0.609	0.011
M07.29 Psoriatic spondylitis (Site unspecified)	0.379	0.609	0.011
M07.28 Psoriatic spondylitis (Other)	0.379	0.609	0.011
M07.27 Psoriatic spondylitis (Ankle and foot)	0.379	0.609	0.011
M07.26 Psoriatic spondylitis (Lower leg)	0.379	0.609	0.011
M07.25 Psoriatic spondylitis (Pelvic region and thigh)	0.379	0.609	0.011
M07.24 Psoriatic spondylitis (Hand)	0.379	0.609	0.011
M07.23 Psoriatic spondylitis (Forearm)	0.379	0.609	0.011
M07.22 Psoriatic spondylitis (Upper arm)	0.379	0.609	0.011
M07.21 Psoriatic spondylitis (Shoulder region)	0.379	0.609	0.011
M07.20 Psoriatic spondylitis (Multiple sites)	0.379	0.609	0.011
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)	0.379	0.609	0.011
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)	0.379	0.609	0.011
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)	0.379	0.609	0.011
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)	0.379	0.609	0.011
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)	0.379	0.609	0.011
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)	0.379	0.609	0.011
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)	0.379	0.609	0.011
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)	0.379	0.609	0.011
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)	0.379	0.609	0.011
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)	0.379	0.609	0.011
M07.59 Arthropathy in ulcerative colitis (Site unspecified)	0.379	0.609	0.011
M07.58 Arthropathy in ulcerative colitis (Other)	0.379	0.609	0.011
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)	0.379	0.609	0.011
M07.56 Arthropathy in ulcerative colitis (Lower leg)	0.379	0.609	0.011
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)	0.379	0.609	0.011
M07.54 Arthropathy in ulcerative colitis (Hand)	0.379	0.609	0.011
M07.53 Arthropathy in ulcerative colitis (Forearm)	0.379	0.609	0.011
M07.52 Arthropathy in ulcerative colitis (Upper arm)	0.379	0.609	0.011
M07.51 Arthropathy in ulcerative colitis (Shoulder region)	0.379	0.609	0.011
M07.50 Arthropathy in ulcerative colitis (Multiple sites)	0.379	0.609	0.011
M07.69 Other enteropathic arthropathies (Site unspecified)	0.379	0.609	0.011
M07.68 Other enteropathic arthropathies (Other)	0.379	0.609	0.011
M07.67 Other enteropathic arthropathies (Ankle and foot)	0.379	0.609	0.011
M07.66 Other enteropathic arthropathies (Lower leg)	0.379	0.609	0.011
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)	0.379	0.609	0.011
M07.64 Other enteropathic arthropathies (Hand)	0.379	0.609	0.011
M07.63 Other enteropathic arthropathies (Forearm)	0.379	0.609	0.011
M07.62 Other enteropathic arthropathies (Upper arm)	0.379	0.609	0.011
M07.61 Other enteropathic arthropathies (Shoulder region)	0.379	0.609	0.011
M07.60 Other enteropathic arthropathies (Multiple sites)	0.379	0.609	0.011
M89.04 Algoneurodystrophy (Hand)	0.390	0.610	0.000
E26 Hyperaldosteronism	0.000	0.610	0.390
M49.8 Spondylopathy in other diseases classified elsewhere	0.389	0.610	0.000
M49.4 Neuropathic spondylopathy	0.389	0.610	0.000
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere	0.389	0.610	0.000
M49.2 Enterobacterial spondylitis	0.389	0.610	0.000
M49.1 Brucella spondylitis	0.389	0.610	0.000
M49.0 Tuberculosis of spine	0.389	0.610	0.000
M10.09 Idiopathic gout (Site unspecified)	0.380	0.612	0.008
M53.3 Sacrococcygeal disorders, not elsewhere classified	0.387	0.613	0.000
M65-M68 Disorders of synovium and tendon	0.387	0.613	0.000
M53.9 Dorsopathy, unspecified	0.386	0.614	0.000
M89.6 Osteopathy after poliomyelitis	0.386	0.614	0.000
M89.4 Other hypertrophic osteo-arthropathy	0.386	0.614	0.000
M89.2 Other disorders of bone development and growth	0.386	0.614	0.000
M89.1 Epiphyseal arrest	0.386	0.614	0.000
M89.94 Disorder of bone, unspecified (Hand)	0.386	0.614	0.000
M47.96 Spondylosis, unspecified (Lumbar region)	0.386	0.614	0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)	0.386	0.614	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.385	0.615	0.000
E15 Nondiabetic hypoglycaemic coma	0.000	0.618	0.382
M08.9 Juvenile arthritis, unspecified	0.356	0.618	0.026
M08.8 Other juvenile arthritis	0.356	0.618	0.026
M08.4 Pauciarticular juvenile arthritis	0.356	0.618	0.026
M08.3 Juvenile polyarthritis (seronegative)	0.356	0.618	0.026
M08.2 Juvenile arthritis with systemic onset	0.356	0.618	0.026
M08.1 Juvenile ankylosing spondylitis	0.356	0.618	0.026
M08.0 Juvenile rheumatoid arthritis	0.356	0.618	0.026
M09.8 Juvenile arthritis in other diseases classified elsewhere	0.356	0.618	0.026
M09.2 Juvenile arthritis in ulcerative colitis	0.356	0.618	0.026
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]	0.356	0.618	0.026
M09.0 Juvenile arthritis in psoriasis	0.356	0.618	0.026
M12.8 Other specific arthropathies, not elsewhere classified	0.356	0.618	0.026
M12.5 Traumatic arthropathy	0.356	0.618	0.026
M12.4 Intermittent hydrarthrosis	0.356	0.618	0.026
M12.3 Palindromic rheumatism	0.356	0.618	0.026
M12.2 Villonodular synovitis (pigmented)	0.356	0.618	0.026
M12.1 Kaschin-Beck disease	0.356	0.618	0.026
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.356	0.618	0.026
M94.3 Chondrolysis	0.381	0.619	0.000
M94.1 Relapsing polychondritis	0.381	0.619	0.000
M94.0 Chondrocostal junction syndrome [Tietze]	0.381	0.619	0.000
E29 Testicular dysfunction	0.000	0.619	0.381
M43.9 Deforming dorsopathy, unspecified	0.380	0.620	0.000
M43.8 Other specified deforming dorsopathies	0.380	0.620	0.000
M43.5 Other recurrent vertebral subluxation	0.380	0.620	0.000
M43.4 Other recurrent atlantoaxial subluxation	0.380	0.620	0.000
M43.3 Recurrent atlantoaxial subluxation with myelopathy	0.380	0.620	0.000
M43.2 Other fusion of spine	0.380	0.620	0.000
M06.0 Seronegative rheumatoid arthritis	0.172	0.620	0.208
M84.3 Stress fracture, not elsewhere classified	0.378	0.622	0.000
M89.92 Disorder of bone, unspecified (Upper arm)	0.378	0.622	0.000
M47.92 Spondylosis, unspecified (Cervical region)	0.377	0.623	0.000
M46.4 Discitis, unspecified	0.376	0.623	0.000
M93 Other osteochondropathies	0.374	0.625	0.000
M84.4 Pathological fracture, not elsewhere classified	0.373	0.627	0.000
M92.5 Juvenile osteochondrosis of tibia and fibula	0.373	0.627	0.000
M92.1 Juvenile osteochondrosis of radius and ulna	0.373	0.627	0.000
M92.9 Juvenile osteochondrosis, unspecified	0.373	0.627	0.000
M92.8 Other specified juvenile osteochondrosis	0.373	0.627	0.000
M92.7 Juvenile osteochondrosis of metatarsus	0.373	0.627	0.000
M92.4 Juvenile osteochondrosis of patella	0.373	0.627	0.000
M92.3 Other juvenile osteochondrosis of upper limb	0.373	0.627	0.000
M92.2 Juvenile osteochondrosis of hand	0.373	0.627	0.000
M92.0 Juvenile osteochondrosis of humerus	0.373	0.627	0.000
M49.56 Collapsed vertebra in diseases classified elsewhere (Lumbar region)	0.372	0.627	0.000
M85.65 Other cyst of bone (Pelvic region and thigh)	0.373	0.627	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.628	0.372
M89.5 Osteolysis	0.372	0.628	0.000
M77.5 Other enthesopathy of foot	0.371	0.628	0.000
M43.19 Spondylolisthesis (Site unspecified)	0.371	0.629	0.000
M77.8 Other enthesopathies, not elsewhere classified	0.370	0.629	0.000
M77.3 Calcaneal spur	0.370	0.629	0.000
M77.2 Periarthritis of wrist	0.370	0.629	0.000
M13 Other arthritis	0.355	0.630	0.015
M94.2 Chondromalacia	0.370	0.630	0.000
E27.8 Other specified disorders of adrenal gland	0.000	0.630	0.370
M43.12 Spondylolisthesis (Cervical region)	0.370	0.630	0.000
M43.0 Spondylolysis	0.369	0.630	0.000
M85.9 Disorder of bone density and structure, unspecified	0.368	0.632	0.000
M85.5 Aneurysmal bone cyst	0.368	0.632	0.000
M85.4 Solitary bone cyst	0.368	0.632	0.000
M85.3 Osteitis condensans	0.368	0.632	0.000
M85.2 Hyperostosis of skull	0.368	0.632	0.000
M85.1 Skeletal fluorosis	0.368	0.632	0.000
M85.80 Other specified disorders of bone density and structure (Multiple sites)	0.368	0.632	0.000
M71.26 Synovial cyst of popliteal space [Baker]-Lower Leg	0.367	0.633	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.633	0.367
E34 Other endocrine disorders	0.000	0.635	0.365
M89.96 Disorder of bone, unspecified (Lower leg)	0.365	0.635	0.000
M94.89 Other specified disorders of cartilage (Site unspecified)	0.364	0.636	0.000
M94.86 Other specified disorders of cartilage (Lower leg)	0.363	0.637	0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.363	0.637	0.000
M51.9 Intervertebral disk disorder, unspecified	0.362	0.638	0.000
E22.1 Hyperprolactinaemia	0.000	0.639	0.361
M50.9 Cervical disk disorder, unspecified	0.361	0.639	0.000
E66 Obesity	0.000	0.640	0.360
E22.0 Acromegaly and pituitary gigantism	0.000	0.641	0.359
M87.91 Osteonecrosis, unspecified (Shoulder region)	0.358	0.642	0.000
M70 Soft tissue disorders related to use, overuse and pressure	0.358	0.642	0.000
M53.2 Spinal instabilities	0.357	0.643	0.000
M53.1 Cervicobrachial syndrome	0.357	0.643	0.000
M53.0 Cervicocranial syndrome	0.357	0.643	0.000
M71.1 Other infective bursitis	0.357	0.643	0.000
M71.9 Bursopathy, unspecified	0.356	0.644	0.000
M71.8 Other specified bursopathies	0.356	0.644	0.000
M71.5 Other bursitis, not elsewhere classified	0.356	0.644	0.000
M71.4 Calcium deposit in bursa	0.356	0.644	0.000
M71.0 Abscess of bursa	0.356	0.644	0.000
M85.0 Fibrous dysplasia (monostotic)	0.356	0.644	0.000
M60 Myositis	0.355	0.644	0.000
M10.08 Idiopathic gout (Other)	0.345	0.645	0.009
M10.07 Idiopathic gout (Ankle and foot)	0.345	0.645	0.009
M10.06 Idiopathic gout (Lower leg)	0.345	0.645	0.009
M10.05 Idiopathic gout (Pelvic region and thigh)	0.345	0.645	0.009
M10.04 Idiopathic gout (Hand)	0.345	0.645	0.009
M10.03 Idiopathic gout (Forearm)	0.345	0.645	0.009
M10.02 Idiopathic gout (Upper arm)	0.345	0.645	0.009
M10.01 Idiopathic gout (Shoulder region)	0.345	0.645	0.009
M10.00 Idiopathic gout (Multiple sites)	0.345	0.645	0.009
L40-L45 Papulosquamous disorders	0.353	0.647	0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)	0.353	0.647	0.000
E44.1 Mild protein-energy malnutrition	0.000	0.647	0.353
E44.0 Moderate protein-energy malnutrition	0.000	0.647	0.353

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations