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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2833197
log Bayes Factor = 0.0509782
Chromosome 21   position 32,407,116  (GRCh37) Explore rs2833197 on Ensembl!
Variant rs2833197 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
0.104 0.896 0.000
Chapter II Neoplasms
0.101 0.899 0.000
Chapter XXI Factors influencing health status and contact with health services
0.098 0.902 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.097 0.903 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.095 0.905 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.094 0.906 0.000
C50-C50 Malignant neoplasm of breast
0.091 0.909 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.091 0.909 0.000
Z85 Personal history of malignant neoplasm
0.090 0.910 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.088 0.912 0.000
M20-M25 Other joint disorders
0.088 0.912 0.000
Chapter I Certain infectious and parasitic diseases
0.085 0.915 0.000
Z85.3 Personal history of malignant neoplasm of breast
0.085 0.915 0.000
R10 Abdominal and pelvic pain
0.085 0.915 0.000
C50 Malignant neoplasm of breast
0.085 0.915 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.083 0.917 0.000
D10-D36 Benign neoplasms
0.083 0.917 0.000
R10.4 Other and unspecified abdominal pain
0.082 0.918 0.000
M20 Acquired deformities of fingers and toes
0.081 0.919 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.081 0.919 0.000
Chapter VII Diseases of the eye and adnexa
0.080 0.920 0.000
M15-M19 Arthrosis
0.080 0.920 0.000
Chapter XIV Diseases of the genitourinary system
0.079 0.921 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.079 0.921 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.078 0.922 0.000
Z88.0 Personal history of allergy to penicillin
0.077 0.923 0.000
C64-C68 Malignant neoplasms of urinary tract
0.076 0.924 0.000
Chapter XI Diseases of the digestive system
0.076 0.924 0.000
Chapter VIII Diseases of the ear and mastoid process
0.076 0.924 0.000
R19 Other symptoms and signs involving the digestive system and abdomen
0.076 0.924 0.000
Z86 Personal history of certain other diseases
0.075 0.925 0.000
M20.1 Hallux valgus (acquired)
0.075 0.925 0.000
C50.9 Breast, unspecified
0.075 0.925 0.000
Z96 Presence of other functional implants
0.075 0.925 0.000
Chapter XXII Codes for special purposes
0.075 0.925 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.075 0.925 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.075 0.925 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.075 0.925 0.000
Chapter X Diseases of the respiratory system
0.074 0.926 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.074 0.926 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.074 0.926 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.074 0.926 0.000
Chapter XX External causes of morbidity and mortality
0.073 0.927 0.000
M45-M49 Spondylopathies
0.073 0.927 0.000
R11 Nausea and vomiting
0.073 0.927 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.073 0.927 0.000
D00-D09 In situ neoplasms
0.073 0.927 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.073 0.927 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.073 0.927 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.073 0.927 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.073 0.927 0.000
C51-C58 Malignant neoplasms of female genital organs
0.073 0.927 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.073 0.927 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.073 0.927 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.073 0.927 0.000
C15-C26 Malignant neoplasms of digestive organs
0.073 0.927 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.073 0.927 0.000
Z85.8 Personal history of malignant neoplasms of other organs and systems
0.073 0.927 0.000
A00-A09 Intestinal infectious diseases
0.072 0.928 0.000
C50.4 Upper-outer quadrant of breast
0.072 0.928 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.072 0.928 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.071 0.929 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.071 0.929 0.000
Chapter VI Diseases of the nervous system
0.071 0.929 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.070 0.929 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.070 0.929 0.000
D25 Leiomyoma of uterus
0.070 0.930 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.069 0.930 0.000
M91-M94 Chondropathies
0.069 0.930 0.000
M86-M90 Other osteopathies
0.069 0.930 0.000
M80-M85 Disorders of bone density and structure
0.069 0.930 0.000
M65-M68 Disorders of synovium and tendon
0.069 0.930 0.000
M60-M63 Disorders of muscles
0.069 0.930 0.000
M50-M54 Other dorsopathies
0.069 0.930 0.000
M40-M43 Deforming dorsopathies
0.069 0.930 0.000
M05-M14 Inflammatory polyarthropathies
0.069 0.930 0.000
M00-M03 Infectious arthropathies
0.069 0.930 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.069 0.931 0.000
Chapter V Mental and behavioural disorders
0.069 0.931 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.069 0.931 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.068 0.932 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.068 0.932 0.000
Z98 Other postsurgical states
0.068 0.932 0.000
Z97 Presence of other devices
0.068 0.932 0.000
Z94 Transplanted organ and tissue status
0.068 0.932 0.000
Z93 Artificial opening status
0.068 0.932 0.000
Z89 Acquired absence of limb
0.068 0.932 0.000
Z84 Family history of other conditions
0.068 0.932 0.000
Z83 Family history of other specific disorders
0.068 0.932 0.000
Z81 Family history of mental and behavioural disorders
0.068 0.932 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.068 0.932 0.000
M17 Gonarthrosis [arthrosis of knee]
0.068 0.932 0.000
R50-R69 General symptoms and signs
0.068 0.932 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.067 0.932 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.067 0.932 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.067 0.932 0.000
R47-R49 Symptoms and signs involving speech and voice
0.067 0.932 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.067 0.932 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.067 0.932 0.000
C60-C63 Malignant neoplasms of male genital organs
0.067 0.933 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.067 0.933 0.000
M70-M79 Other soft tissue disorders
0.067 0.933 0.000
Z80 Family history of malignant neoplasm
0.066 0.933 0.000
Z85.5 Personal history of malignant neoplasm of urinary tract
0.066 0.934 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.065 0.934 0.000
R10.1 Pain localised to upper abdomen
0.065 0.934 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.065 0.935 0.000
R18 Ascites
0.065 0.935 0.000
R17 Unspecified jaundice
0.065 0.935 0.000
R15 Faecal incontinence
0.065 0.935 0.000
R14 Flatulence and related conditions
0.065 0.935 0.000
R12 Heartburn
0.065 0.935 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.065 0.935 0.000
R19.4 Change in bowel habit
0.065 0.935 0.000
M20.4 Other hammer toe(s) (acquired)
0.065 0.935 0.000
Z85.0 Personal history of malignant neoplasm of digestive organs
0.065 0.935 0.000
Z85.9 Personal history of malignant neoplasm, unspecified
0.065 0.935 0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
0.065 0.935 0.000
Z85.6 Personal history of leukaemia
0.065 0.935 0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs
0.065 0.935 0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung
0.065 0.935 0.000
N20-N23 Urolithiasis
0.064 0.935 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.064 0.936 0.000
Z96.6 Presence of orthopaedic joint implants
0.064 0.936 0.000
C80 Malignant neoplasm without specification of site
0.063 0.937 0.000
C79 Secondary malignant neoplasm of other sites
0.063 0.937 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.063 0.937 0.000
Z87 Personal history of other diseases and conditions
0.063 0.937 0.000
M23 Internal derangement of knee
0.063 0.937 0.000
H40-H42 Glaucoma
0.063 0.937 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.063 0.937 0.000
M35 Other systemic involvement of connective tissue
0.063 0.937 0.000
M34 Systemic sclerosis
0.063 0.937 0.000
M33 Dermatopolymyositis
0.063 0.937 0.000
M32 Systemic lupus erythematosus
0.063 0.937 0.000
M31 Other necrotising vasculopathies
0.063 0.937 0.000
M30 Polyarteritis nodosa and related conditions
0.063 0.937 0.000
M25 Other joint disorders, not elsewhere classified
0.063 0.937 0.000
M24 Other specific joint derangements
0.063 0.937 0.000
M22 Disorders of patella
0.063 0.937 0.000
M21 Other acquired deformities of limbs
0.063 0.937 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.063 0.937 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.063 0.937 0.000
Z85.4 Personal history of malignant neoplasm of genital organs
0.063 0.937 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.062 0.937 0.000
C78.0 Secondary malignant neoplasm of lung
0.062 0.937 0.000
R13 Dysphagia
0.062 0.938 0.000
B95-B98 Bacterial, viral and other infectious agents
0.061 0.938 0.000
B99-B99 Other infectious diseases
0.061 0.938 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.061 0.938 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.061 0.938 0.000
B65-B83 Helminthiases
0.061 0.938 0.000
B50-B64 Protozoal diseases
0.061 0.938 0.000
B35-B49 Mycoses
0.061 0.938 0.000
B25-B34 Other viral diseases
0.061 0.938 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.061 0.938 0.000
B15-B19 Viral hepatitis
0.061 0.938 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.061 0.938 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.061 0.938 0.000
A80-A89 Viral infections of the central nervous system
0.061 0.938 0.000
A75-A79 Rickettsioses
0.061 0.938 0.000
A70-A74 Other diseases caused by chlamydiae
0.061 0.938 0.000
A65-A69 Other spirochaetal diseases
0.061 0.938 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.061 0.938 0.000
A30-A49 Other bacterial diseases
0.061 0.938 0.000
A20-A28 Certain zoonotic bacterial diseases
0.061 0.938 0.000
A15-A19 Tuberculosis
0.061 0.938 0.000
Z09.8 Follow-up examination after other treatment for other conditions
0.061 0.939 0.000
C50.8 Overlapping lesion of breast
0.061 0.939 0.000
C50.6 Axillary tail of breast
0.061 0.939 0.000
C50.5 Lower-outer quadrant of breast
0.061 0.939 0.000
C50.3 Lower-inner quadrant of breast
0.061 0.939 0.000
C50.2 Upper-inner quadrant of breast
0.061 0.939 0.000
C50.1 Central portion of breast
0.061 0.939 0.000
C50.0 Nipple and areola
0.061 0.939 0.000
R10.2 Pelvic and perineal pain
0.061 0.939 0.000
R10.0 Acute abdomen
0.061 0.939 0.000
N30-N39 Other diseases of urinary system
0.061 0.939 0.000
D25.9 Leiomyoma of uterus, unspecified
0.060 0.939 0.000
Z13 Special screening examination for other diseases and disorders
0.060 0.940 0.000
S70-S79 Injuries to the hip and thigh
0.060 0.940 0.000
H30-H36 Disorders of choroid and retina
0.060 0.940 0.000
C77.3 Axillary and upper limb lymph nodes
0.060 0.940 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.060 0.940 0.000
Z88.7 Personal history of allergy to serum and vaccine
0.060 0.940 0.000
Z88.5 Personal history of allergy to narcotic agent
0.060 0.940 0.000
Z88.4 Personal history of allergy to anaesthetic agent
0.060 0.940 0.000
Z88.3 Personal history of allergy to other anti-infective agents
0.060 0.940 0.000
Z88.2 Personal history of allergy to sulphonamides
0.060 0.940 0.000
Z88.1 Personal history of allergy to other antibiotic agents
0.060 0.940 0.000
D36 Benign neoplasm of other and unspecified sites
0.059 0.940 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.059 0.940 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.059 0.940 0.000
D32 Benign neoplasm of meninges
0.059 0.940 0.000
D31 Benign neoplasm of eye and adnexa
0.059 0.940 0.000
D30 Benign neoplasm of urinary organs
0.059 0.940 0.000
D29 Benign neoplasm of male genital organs
0.059 0.940 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.059 0.940 0.000
D26 Other benign neoplasms of uterus
0.059 0.940 0.000
D23 Other benign neoplasms of skin
0.059 0.940 0.000
D22 Melanocytic naevi
0.059 0.940 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.059 0.940 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.059 0.940 0.000
D19 Benign neoplasm of mesothelial tissue
0.059 0.940 0.000
D18 Haemangioma and lymphangioma, any site
0.059 0.940 0.000
D17 Benign lipomatous neoplasm
0.059 0.940 0.000
D16 Benign neoplasm of bone and articular cartilage
0.059 0.940 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.059 0.940 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.059 0.940 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.059 0.940 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.059 0.940 0.000
D11 Benign neoplasm of major salivary glands
0.059 0.940 0.000
D10 Benign neoplasm of mouth and pharynx
0.059 0.940 0.000
D34 Benign neoplasm of thyroid gland
0.059 0.940 0.000
D27 Benign neoplasm of ovary
0.059 0.940 0.000
D24 Benign neoplasm of breast
0.059 0.940 0.000
Z86.0 Personal history of other neoplasms
0.059 0.941 0.000
C67 Malignant neoplasm of bladder
0.059 0.941 0.000
M16 Coxarthrosis [arthrosis of hip]
0.059 0.941 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.058 0.941 0.000
M20.5 Other deformities of toe(s) (acquired)
0.058 0.941 0.000
M20.3 Other deformity of hallux (acquired)
0.058 0.941 0.000
M20.2 Hallux rigidus
0.058 0.941 0.000
M20.0 Deformity of finger(s)
0.058 0.941 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.058 0.942 0.000
Z10 Routine general health check-up of defined subpopulation
0.058 0.942 0.000
Z04 Examination and observation for other reasons
0.058 0.942 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.058 0.942 0.000
Z02 Examination and encounter for administrative purposes
0.058 0.942 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.058 0.942 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.058 0.942 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.058 0.942 0.000
L60-L75 Disorders of skin appendages
0.058 0.942 0.000
H55-H59 Other disorders of eye and adnexa
0.057 0.942 0.000
H53-H54 Visual disturbances and blindness
0.057 0.942 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.057 0.942 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.057 0.942 0.000
H43-H45 Disorders of vitreous body and globe
0.057 0.942 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.057 0.942 0.000
H10-H13 Disorders of conjunctiva
0.057 0.942 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.057 0.942 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.057 0.942 0.000
M18 Arthrosis of first carpometacarpal joint
0.057 0.943 0.000
M15 Polyarthrosis
0.057 0.943 0.000
M17.0 Primary gonarthrosis, bilateral
0.057 0.943 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.057 0.943 0.000
N99-N99 Other disorders of the genitourinary system
0.057 0.943 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.057 0.943 0.000
N60-N64 Disorders of breast
0.057 0.943 0.000
N25-N29 Other disorders of kidney and ureter
0.057 0.943 0.000
N10-N16 Renal tubulo-interstitial diseases
0.057 0.943 0.000
N00-N08 Glomerular diseases
0.057 0.943 0.000
K40-K46 Hernia
0.057 0.943 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.057 0.943 0.000
Z88.6 Personal history of allergy to analgesic agent
0.057 0.943 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.057 0.943 0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances
0.057 0.943 0.000
K90-K93 Other diseases of the digestive system
0.057 0.943 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.057 0.943 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.056 0.943 0.000
T79-T79 Certain early complications of trauma
0.056 0.943 0.000
T66-T78 Other and unspecified effects of external causes
0.056 0.943 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.056 0.943 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.056 0.943 0.000
T33-T35 Frostbite
0.056 0.943 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.056 0.943 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.056 0.943 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.056 0.943 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.056 0.943 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.056 0.943 0.000
T00-T07 Injuries involving multiple body regions
0.056 0.943 0.000
S90-S99 Injuries to the ankle and foot
0.056 0.943 0.000
S80-S89 Injuries to the knee and lower leg
0.056 0.943 0.000
S60-S69 Injuries to the wrist and hand
0.056 0.943 0.000
S50-S59 Injuries to the elbow and forearm
0.056 0.943 0.000
S40-S49 Injuries to the shoulder and upper arm
0.056 0.943 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.056 0.943 0.000
S20-S29 Injuries to the thorax
0.056 0.943 0.000
S10-S19 Injuries to the neck
0.056 0.943 0.000
S00-S09 Injuries to the head
0.056 0.943 0.000
J20-J22 Other acute lower respiratory infections
0.056 0.944 0.000
A09.9 Gastroenteritis and colitis of unspecified origin
0.056 0.944 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.056 0.944 0.000
L50-L54 Urticaria and erythema
0.056 0.944 0.000
L40-L45 Papulosquamous disorders
0.056 0.944 0.000
L20-L30 Dermatitis and eczema
0.056 0.944 0.000
L10-L14 Bullous disorders
0.056 0.944 0.000
C78.7 Secondary malignant neoplasm of liver
0.056 0.944 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.056 0.944 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.056 0.944 0.000
H90-H95 Other disorders of ear
0.056 0.944 0.000
Z86.7 Personal history of diseases of the circulatory system
0.056 0.944 0.000
Z12 Special screening examination for neoplasms
0.055 0.944 0.000
Z86.4 Personal history of psychoactive substance abuse
0.056 0.944 0.000
M48 Other spondylopathies
0.055 0.944 0.000
M19 Other arthrosis
0.055 0.945 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.055 0.945 0.000
C66 Malignant neoplasm of ureter
0.055 0.945 0.000
C65 Malignant neoplasm of renal pelvis
0.055 0.945 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.055 0.945 0.000
J40-J47 Chronic lower respiratory diseases
0.055 0.945 0.000
N17-N19 Renal failure
0.055 0.945 0.000
K70-K77 Diseases of liver
0.055 0.945 0.000
K65-K67 Diseases of peritoneum
0.055 0.945 0.000
K35-K38 Diseases of appendix
0.055 0.945 0.000
H80-H83 Diseases of inner ear
0.055 0.945 0.000
H65-H75 Diseases of middle ear and mastoid
0.055 0.945 0.000
H60-H62 Diseases of external ear
0.055 0.945 0.000
C44 Other malignant neoplasms of skin
0.054 0.945 0.000
R19.8 Other specified symptoms and signs involving the digestive system and abdomen
0.054 0.945 0.000
R19.6 Halitosis
0.054 0.945 0.000
R19.5 Other fecal abnormalities
0.054 0.945 0.000
R19.3 Abdominal rigidity
0.054 0.945 0.000
R19.2 Visible peristalsis
0.054 0.945 0.000
R19.1 Abnormal bowel sounds
0.054 0.945 0.000
R19.0 Intra-abdominal and pelvic swelling, mass and lump
0.054 0.945 0.000
Z86.6 Personal history of diseases of the nervous system and sense organs
0.054 0.946 0.000
Z86.5 Personal history of other mental and behavioural disorders
0.054 0.946 0.000
Z86.3 Personal history of endocrine, nutritional and metabolic diseases
0.054 0.946 0.000
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.054 0.946 0.000
Z86.1 Personal history of infectious and parasitic diseases
0.054 0.946 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.054 0.946 0.000
Z96.9 Presence of functional implant, unspecified
0.054 0.946 0.000
Z96.8 Presence of other specified functional implants
0.054 0.946 0.000
Z96.7 Presence of other bone and tendon implants
0.054 0.946 0.000
Z96.5 Presence of tooth-root and mandibular implants
0.054 0.946 0.000
Z96.4 Presence of endocrine implants
0.054 0.946 0.000
Z96.3 Presence of artificial larynx
0.054 0.946 0.000
Z96.2 Presence of otological and audiological implants
0.054 0.946 0.000
Z96.0 Presence of urogenital implants
0.054 0.946 0.000
Z92 Personal history of medical treatment
0.054 0.946 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.054 0.946 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.054 0.946 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.054 0.946 0.000
O85-O92 Complications predominantly related to the puerperium
0.054 0.946 0.000
O80-O84 Delivery
0.054 0.946 0.000
O60-O75 Complications of labour and delivery
0.054 0.946 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.054 0.946 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.054 0.946 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.054 0.946 0.000
O00-O08 Pregnancy with abortive outcome
0.054 0.946 0.000
P90-P96 Other disorders originating in the perinatal period
0.054 0.946 0.000
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn
0.054 0.946 0.000
P75-P78 Digestive system disorders of fetus and newborn
0.054 0.946 0.000
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn
0.054 0.946 0.000
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn
0.054 0.946 0.000
P35-P39 Infections specific to the perinatal period
0.054 0.946 0.000
P20-P29 Respiratory and cardiovascular disorders specific to the perinatal period
0.054 0.946 0.000
P10-P15 Birth trauma
0.054 0.946 0.000
P05-P08 Disorders related to length of gestation and fetal growth
0.054 0.946 0.000
P00-P04 Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery
0.054 0.946 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.054 0.946 0.000
Q80-Q89 Other congenital malformations
0.054 0.946 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.054 0.946 0.000
Q60-Q64 Congenital malformations of the urinary system
0.054 0.946 0.000
Q50-Q56 Congenital malformations of genital organs
0.054 0.946 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.054 0.946 0.000
Q35-Q37 Cleft lip and cleft palate
0.054 0.946 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.054 0.946 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.054 0.946 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.054 0.946 0.000
Q00-Q07 Congenital malformations of the nervous system
0.054 0.946 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.054 0.946 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.054 0.946 0.000
K50-K52 Noninfective enteritis and colitis
0.054 0.946 0.000
H25-H28 Disorders of lens
0.053 0.946 0.000
J95-J99 Other diseases of the respiratory system
0.053 0.946 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.053 0.946 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.053 0.946 0.000
J60-J70 Lung diseases due to external agents
0.053 0.946 0.000
J00-J06 Acute upper respiratory infections
0.053 0.946 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.053 0.947 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.053 0.947 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.053 0.947 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.053 0.947 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.053 0.947 0.000
C78.2 Secondary malignant neoplasm of pleura
0.053 0.947 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.053 0.947 0.000
J90-J94 Other diseases of pleura
0.053 0.947 0.000
C43 Malignant melanoma of skin
0.053 0.947 0.000
D80-D89 Certain disorders involving the immune mechanism
0.053 0.947 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.053 0.947 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.053 0.947 0.000
D55-D59 Haemolytic anaemias
0.053 0.947 0.000
D50-D53 Nutritional anaemias
0.053 0.947 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.053 0.947 0.000
M17.9 Gonarthrosis, unspecified
0.053 0.947 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.053 0.947 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.053 0.947 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.053 0.947 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.053 0.947 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.053 0.947 0.000
Y35-Y36 Legal intervention and operations of war
0.053 0.947 0.000
Y10-Y34 Event of undetermined intent
0.053 0.947 0.000
Y00-Y09 Assault
0.053 0.947 0.000
X85-X99 Assault
0.053 0.947 0.000
X60-X84 Intentional self-harm
0.053 0.947 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.053 0.947 0.000
X50-X57 Overexertion, travel and privation
0.053 0.947 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.053 0.947 0.000
X30-X39 Exposure to forces of nature
0.053 0.947 0.000
X20-X29 Contact with venomous animals and plants
0.053 0.947 0.000
X10-X19 Contact with heat and hot substances
0.053 0.947 0.000
X00-X09 Exposure to smoke, fire and flames
0.053 0.947 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.053 0.947 0.000
W75-W84 Other accidental threats to breathing
0.053 0.947 0.000
W65-W74 Accidental drowning and submersion
0.053 0.947 0.000
W50-W64 Exposure to animate mechanical forces
0.053 0.947 0.000
W20-W49 Exposure to inanimate mechanical forces
0.053 0.947 0.000
W00-W19 Falls
0.053 0.947 0.000
V98-V99 Other and unspecified transport accidents
0.053 0.947 0.000
V95-V97 Air and space transport accidents
0.053 0.947 0.000
V90-V94 Water transport accidents
0.053 0.947 0.000
V80-V89 Other land transport accidents
0.053 0.947 0.000
V70-V79 Bus occupant injured in transport accident
0.053 0.947 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.053 0.947 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.053 0.947 0.000
V40-V49 Car occupant injured in transport accident
0.053 0.947 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.053 0.947 0.000
V20-V29 Motorcycle rider injured in transport accident
0.053 0.947 0.000
V10-V19 Pedal cyclist injured in transport accident
0.053 0.947 0.000
V01-V09 Pedestrian injured in transport accident
0.053 0.947 0.000
M49 Spondylopathies in diseases classified elsewhere
0.052 0.948 0.000
M47 Spondylosis
0.052 0.948 0.000
M46 Other inflammatory spondylopathies
0.052 0.948 0.000
M45 Ankylosing spondylitis
0.052 0.948 0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.052 0.948 0.000
C13 Malignant neoplasm of hypopharynx
0.052 0.948 0.000
C11 Malignant neoplasm of nasopharynx
0.052 0.948 0.000
C10 Malignant neoplasm of oropharynx
0.052 0.948 0.000
C09 Malignant neoplasm of tonsil
0.052 0.948 0.000
C08 Malignant neoplasm of other and unspecified major salivary glands
0.052 0.948 0.000
C06 Malignant neoplasm of other and unspecified parts of mouth
0.052 0.948 0.000
C05 Malignant neoplasm of palate
0.052 0.948 0.000
C04 Malignant neoplasm of floor of mouth
0.052 0.948 0.000
C03 Malignant neoplasm of gum
0.052 0.948 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.052 0.948 0.000
C00 Malignant neoplasm of lip
0.052 0.948 0.000
C12 Malignant neoplasm of pyriform sinus
0.052 0.948 0.000
C07 Malignant neoplasm of parotid gland
0.052 0.948 0.000
C01 Malignant neoplasm of base of tongue
0.052 0.948 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.052 0.948 0.000
C25 Malignant neoplasm of pancreas
0.052 0.948 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.052 0.948 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.052 0.948 0.000
C21 Malignant neoplasm of anus and anal canal
0.052 0.948 0.000
C18 Malignant neoplasm of colon
0.052 0.948 0.000
C17 Malignant neoplasm of small intestine
0.052 0.948 0.000
C16 Malignant neoplasm of stomach
0.052 0.948 0.000
C15 Malignant neoplasm of oesophagus
0.052 0.948 0.000
C23 Malignant neoplasm of gallbladder
0.052 0.948 0.000
C20 Malignant neoplasm of rectum
0.052 0.948 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.052 0.948 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.052 0.948 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.052 0.948 0.000
C34 Malignant neoplasm of bronchus and lung
0.052 0.948 0.000
C32 Malignant neoplasm of larynx
0.052 0.948 0.000
C31 Malignant neoplasm of accessory sinuses
0.052 0.948 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.052 0.948 0.000
C37 Malignant neoplasm of thymus
0.052 0.948 0.000
C33 Malignant neoplasm of trachea
0.052 0.948 0.000
C42 hematopoietic and reticuloendothelial systems (ICD-O-3 specific)
0.052 0.948 0.000
C41 Malignant neoplasm of bone and articular cartilage of other and unspecified sites
0.052 0.948 0.000
C40 Malignant neoplasm of bone and articular cartilage of limbs
0.052 0.948 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.052 0.948 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.052 0.948 0.000
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system
0.052 0.948 0.000
C46 Kaposi's sarcoma
0.052 0.948 0.000
C45 Mesothelioma
0.052 0.948 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.052 0.948 0.000
C54 Malignant neoplasm of corpus uteri
0.052 0.948 0.000
C53 Malignant neoplasm of cervix uteri
0.052 0.948 0.000
C51 Malignant neoplasm of vulva
0.052 0.948 0.000
C58 Malignant neoplasm of placenta
0.052 0.948 0.000
C56 Malignant neoplasm of ovary
0.052 0.948 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.052 0.948 0.000
C52 Malignant neoplasm of vagina
0.052 0.948 0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system
0.052 0.948 0.000
C71 Malignant neoplasm of brain
0.052 0.948 0.000
C70 Malignant neoplasm of meninges
0.052 0.948 0.000
C69 Malignant neoplasm of eye and adnexa
0.052 0.948 0.000
C75 Malignant neoplasm of other endocrine glands and related structures
0.052 0.948 0.000
C74 Malignant neoplasm of adrenal gland
0.052 0.948 0.000
C73 Malignant neoplasm of thyroid gland
0.052 0.948 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.052 0.948 0.000
C95 Leukaemia of unspecified cell type
0.052 0.948 0.000
C94 Other leukaemias of specified cell type
0.052 0.948 0.000
C93 Monocytic leukaemia
0.052 0.948 0.000
C92 Myeloid leukaemia
0.052 0.948 0.000
C91 Lymphoid leukaemia
0.052 0.948 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.052 0.948 0.000
C88 Malignant immunoproliferative diseases
0.052 0.948 0.000
C86 Other specified types of T/NK-cell lymphoma
0.052 0.948 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.052 0.948 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.052 0.948 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.052 0.948 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.052 0.948 0.000
C81 Hodgkin's disease
0.052 0.948 0.000
C97 Malignant neoplasms of independent (primary) multiple sites
0.052 0.948 0.000
D09 Carcinoma in situ of other and unspecified sites
0.052 0.948 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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