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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs28359571
log Bayes Factor = 29.6077
Chromosome 1   position 230,881,876  (GRCh37) Explore rs28359571 on Ensembl!
Variant rs28359571 is part of Cluster X0164

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
1.000 0.000 0.000
Z86 Personal history of certain other diseases
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
Chapter V Mental and behavioural disorders
0.999 0.001 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.998 0.002 0.000
Z92 Personal history of medical treatment
0.998 0.002 0.000
Z51 Other medical care
0.997 0.003 0.000
Chapter I Certain infectious and parasitic diseases
0.995 0.005 0.000
E70-E90 Metabolic disorders
0.993 0.007 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.992 0.008 0.000
Z72 Problems related to lifestyle
0.992 0.008 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.992 0.008 0.000
Z51.5 Palliative care
0.990 0.010 0.000
Chapter VII Diseases of the eye and adnexa
0.988 0.012 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.988 0.012 0.000
Chapter II Neoplasms
0.988 0.012 0.000
Z86.0 Personal history of other neoplasms
0.986 0.014 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.986 0.014 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.985 0.015 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.984 0.016 0.000
Z50 Care involving use of rehabilitation procedures
0.982 0.018 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.982 0.018 0.000
M05-M14 Inflammatory polyarthropathies
0.981 0.019 0.000
Z72.0 Tobacco use
0.977 0.023 0.000
Z86.7 Personal history of diseases of the circulatory system
0.977 0.023 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
0.976 0.024 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.975 0.025 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.975 0.025 0.000
I80 Phlebitis and thrombophlebitis
0.970 0.030 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.969 0.031 0.000
Chapter VI Diseases of the nervous system
0.966 0.034 0.000
M13 Other arthritis
0.964 0.036 0.000
F30-F39 Mood [affective] disorders
0.962 0.038 0.000
Z88.6 Personal history of allergy to analgesic agent
0.958 0.042 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.957 0.043 0.000
F10.1 Harmful use
0.956 0.044 0.000
E20-E35 Disorders of other endocrine glands
0.955 0.045 0.000
M13.9 Arthritis, unspecified
0.952 0.048 0.000
I30-I52 Other forms of heart disease
0.950 0.050 0.000
Z86.1 Personal history of infectious and parasitic diseases
0.947 0.053 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.946 0.054 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.945 0.055 0.000
B95-B98 Bacterial, viral and other infectious agents
0.944 0.056 0.000
C79 Secondary malignant neoplasm of other sites
0.942 0.058 0.000
S80-S89 Injuries to the knee and lower leg
0.941 0.059 0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances
0.939 0.061 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.938 0.062 0.000
Z50.1 Other physical therapy
0.937 0.063 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.937 0.063 0.000
Chapter XX External causes of morbidity and mortality
0.931 0.069 0.000
Z42 Follow-up care involving plastic surgery
0.929 0.071 0.000
Z09.0 Follow-up examination after surgery for other conditions
0.929 0.071 0.000
Z43 Attention to artificial openings
0.925 0.075 0.000
G90-G99 Other disorders of the nervous system
0.923 0.077 0.000
E87.5 Hyperkalaemia
0.923 0.077 0.000
F32 Depressive episode
0.922 0.078 0.000
I10-I15 Hypertensive diseases
0.919 0.081 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.915 0.085 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.912 0.088 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.909 0.091 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.909 0.091 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.907 0.093 0.000
Z93 Artificial opening status
0.906 0.094 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.903 0.097 0.000
Z83 Family history of other specific disorders
0.901 0.099 0.000
Z51.3 Blood transfusion without reported diagnosis
0.898 0.102 0.000
D60-D64 Aplastic and other anaemias
0.898 0.102 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.896 0.104 0.000
S00-S09 Injuries to the head
0.895 0.105 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.894 0.106 0.000
M45-M49 Spondylopathies
0.890 0.110 0.000
C77.1 Intrathoracic lymph nodes
0.890 0.110 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.888 0.112 0.000
Z51.0 Radiotherapy session
0.888 0.112 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.886 0.114 0.000
F32.9 Depressive episode, unspecified
0.884 0.116 0.000
Z72.1 Alcohol use
0.883 0.117 0.000
Z13 Special screening examination for other diseases and disorders
0.881 0.119 0.000
I44 Atrioventricular and left bundle-branch block
0.879 0.121 0.000
Z73 Problems related to life-management difficulty
0.878 0.122 0.000
F10.3 Withdrawal state
0.875 0.125 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.875 0.125 0.000
B35-B49 Mycoses
0.871 0.129 0.000
A00-A09 Intestinal infectious diseases
0.864 0.136 0.000
C15-C26 Malignant neoplasms of digestive organs
0.864 0.136 0.000
I10 Essential (primary) hypertension
0.862 0.138 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.860 0.140 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.860 0.140 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.859 0.141 0.000
E87.6 Hypokalaemia
0.857 0.143 0.000
H30-H36 Disorders of choroid and retina
0.856 0.144 0.000
I73 Other peripheral vascular diseases
0.855 0.145 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.854 0.146 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.853 0.147 0.000
Z42.1 Follow-up care involving plastic surgery of breast
0.851 0.149 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.849 0.151 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.849 0.151 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.849 0.151 0.000
Z50.5 Speech therapy
0.848 0.152 0.000
B25-B34 Other viral diseases
0.847 0.153 0.000
Chapter VIII Diseases of the ear and mastoid process
0.847 0.153 0.000
S80 Superficial injury of lower leg
0.847 0.153 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.845 0.155 0.000
E87.2 Acidosis
0.845 0.155 0.000
Z92.3 Personal history of irradiation
0.845 0.155 0.000
E16 Other disorders of pancreatic internal secretion
0.844 0.156 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.844 0.156 0.000
A30-A49 Other bacterial diseases
0.843 0.157 0.000
M11 Other crystal arthropathies
0.839 0.161 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.836 0.164 0.000
Z88.1 Personal history of allergy to other antibiotic agents
0.832 0.168 0.000
H40-H42 Glaucoma
0.831 0.169 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.826 0.174 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.825 0.175 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.825 0.175 0.000
Z51.2 Other chemotherapy
0.824 0.176 0.000
Chapter XXII Codes for special purposes
0.824 0.176 0.000
I44.7 Left bundle-branch block, unspecified
0.823 0.177 0.000
E83 Disorders of mineral metabolism
0.822 0.177 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.821 0.178 0.000
E34 Other endocrine disorders
0.820 0.180 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.819 0.181 0.000
Z60 Problems related to social environment
0.818 0.182 0.000
Z50.8 Care involving use of rehabilitation procedures
0.817 0.183 0.000
I81 Portal vein thrombosis
0.816 0.184 0.000
H55-H59 Other disorders of eye and adnexa
0.815 0.184 0.000
Z96 Presence of other functional implants
0.815 0.185 0.000
C77.3 Axillary and upper limb lymph nodes
0.814 0.186 0.000
G91 Hydrocephalus
0.814 0.186 0.000
M86-M90 Other osteopathies
0.812 0.188 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.811 0.189 0.000
Z93.3 Colostomy status
0.811 0.189 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.810 0.190 0.000
Z92.0 Personal history of contraception
0.809 0.191 0.000
Z83.7 Family history of diseases of the digestive system
0.809 0.191 0.000
E87.0 Hyperosmolality and hypernatraemia
0.809 0.191 0.000
Z22 Carrier of infectious disease
0.809 0.191 0.000
Z13.6 Special screening examination for cardiovascular disorders
0.808 0.192 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.808 0.192 0.000
I60-I69 Cerebrovascular diseases
0.805 0.195 0.000
S00 Superficial injury of head
0.805 0.195 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.804 0.196 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.803 0.197 0.000
I87 Other disorders of veins
0.803 0.197 0.000
C79.2 Secondary malignant neoplasm of skin
0.802 0.198 0.000
I35 Nonrheumatic aortic valve disorders
0.802 0.198 0.000
G93 Other disorders of brain
0.801 0.199 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.801 0.199 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.801 0.199 0.000
Z72.2 Drug use
0.800 0.200 0.000
I82 Other venous embolism and thrombosis
0.799 0.201 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.798 0.202 0.000
E16.2 Hypoglycaemia, unspecified
0.798 0.202 0.000
D64 Other anaemias
0.797 0.203 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.797 0.203 0.000
Z75 Problems related to medical facilities and other health care
0.796 0.203 0.000
Z43.1 Attention to gastrostomy
0.796 0.204 0.000
C77.5 Intrapelvic lymph nodes
0.795 0.205 0.000
C77.9 Lymph node, unspecified
0.794 0.206 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.793 0.207 0.000
Z88.7 Personal history of allergy to serum and vaccine
0.793 0.207 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.791 0.209 0.000
M50-M54 Other dorsopathies
0.791 0.209 0.000
I34 Nonrheumatic mitral valve disorders
0.790 0.210 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.789 0.211 0.000
Z97 Presence of other devices
0.788 0.212 0.000
M48 Other spondylopathies
0.787 0.213 0.000
Z50.2 Alcohol rehabilitation
0.784 0.215 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.784 0.216 0.000
B37 Candidiasis
0.783 0.217 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.782 0.218 0.000
S40-S49 Injuries to the shoulder and upper arm
0.780 0.220 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.779 0.221 0.000
Z88.5 Personal history of allergy to narcotic agent
0.779 0.221 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.779 0.221 0.000
Z13.9 Special screening examination, unspecified
0.778 0.222 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.778 0.222 0.000
I42 Cardiomyopathy
0.778 0.222 0.000
I73.0 Raynaud's syndrome
0.776 0.224 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.776 0.224 0.000
H25-H28 Disorders of lens
0.774 0.226 0.000
E88 Other metabolic disorders
0.773 0.227 0.000
S90-S99 Injuries to the ankle and foot
0.773 0.227 0.000
D80-D89 Certain disorders involving the immune mechanism
0.772 0.228 0.000
H10-H13 Disorders of conjunctiva
0.772 0.228 0.000
I49 Other cardiac arrhythmias
0.772 0.228 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.771 0.229 0.000
Z98 Other postsurgical states
0.771 0.229 0.000
E22 Hyperfunction of pituitary gland
0.770 0.230 0.000
Z43.2 Attention to ileostomy
0.769 0.231 0.000
C15 Malignant neoplasm of oesophagus
0.769 0.231 0.000
G20-G26 Extrapyramidal and movement disorders
0.766 0.234 0.000
M60-M63 Disorders of muscles
0.765 0.235 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.765 0.235 0.000
F31 Bipolar affective disorder
0.764 0.236 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.764 0.236 0.000
Z86.6 Personal history of diseases of the nervous system and sense organs
0.763 0.237 0.000
Z60.2 Living alone
0.763 0.237 0.000
Z86.5 Personal history of other mental and behavioural disorders
0.761 0.239 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.761 0.239 0.000
S50-S59 Injuries to the elbow and forearm
0.760 0.240 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.760 0.240 0.000
M45 Ankylosing spondylitis
0.760 0.240 0.000
C77.4 Inguinal and lower limb lymph nodes
0.757 0.242 0.000
L20-L30 Dermatitis and eczema
0.756 0.244 0.000
Z47 Other orthopaedic follow-up care
0.756 0.244 0.000
M65-M68 Disorders of synovium and tendon
0.756 0.244 0.000
E65-E68 Obesity and other hyperalimentation
0.755 0.245 0.000
G95 Other diseases of spinal cord
0.754 0.246 0.000
A80-A89 Viral infections of the central nervous system
0.754 0.246 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.754 0.246 0.000
S82 Fracture of lower leg, including ankle
0.753 0.247 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.752 0.248 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.752 0.248 0.000
H43-H45 Disorders of vitreous body and globe
0.752 0.248 0.000
E29 Testicular dysfunction
0.751 0.249 0.000
Z43.6 Attention to other artificial openings of urinary tract
0.751 0.249 0.000
Z42.2 Follow-up care involving plastic surgery of other parts of trunk
0.750 0.250 0.000
I44.1 Atrioventricular block, second degree
0.750 0.250 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.749 0.250 0.000
I89.0 Lymphoedema, not elsewhere classified
0.749 0.251 0.000
Z49 Care involving dialysis
0.748 0.252 0.000
Z88.3 Personal history of allergy to other anti-infective agents
0.748 0.252 0.000
I95 Hypotension
0.747 0.253 0.000
Z73.3 Stress, not elsewhere classified
0.747 0.253 0.000
S10-S19 Injuries to the neck
0.746 0.254 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.745 0.255 0.000
I72 Other aneurysm
0.744 0.256 0.000
B34 Viral infection of unspecified site
0.742 0.258 0.000
F99-F99 Unspecified mental disorder
0.741 0.259 0.000
Z22.3 Carrier of other specified bacterial diseases
0.741 0.259 0.000
I51 Complications and ill-defined descriptions of heart disease
0.741 0.259 0.000
I63 Cerebral infarction
0.740 0.260 0.000
T66-T78 Other and unspecified effects of external causes
0.740 0.260 0.000
C77.0 Lymph nodes of head, face and neck
0.739 0.261 0.000
H90-H95 Other disorders of ear
0.738 0.262 0.000
M06 Other rheumatoid arthritis
0.738 0.262 0.000
G30-G32 Other degenerative diseases of the nervous system
0.738 0.262 0.000
R79 Other abnormal findings of blood chemistry
0.738 0.262 0.000
M11.2 Other chondrocalcinosis
0.737 0.263 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.737 0.263 0.000
I80.8 Phlebitis and thrombophlebitis of other sites
0.736 0.264 0.000
G91.9 Hydrocephalus, unspecified
0.735 0.265 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.735 0.265 0.000
X20-X29 Contact with venomous animals and plants
0.734 0.266 0.000
S80.1 Contusion of other and unspecified parts of lower leg
0.733 0.267 0.000
Z93.1 Gastrostomy status
0.732 0.268 0.000
R25 Abnormal involuntary movements
0.732 0.268 0.000
C80 Malignant neoplasm without specification of site
0.732 0.268 0.000
R47-R49 Symptoms and signs involving speech and voice
0.730 0.270 0.000
H20 Iridocyclitis
0.729 0.271 0.000
Z03.8 Observation for other suspected diseases and conditions
0.729 0.271 0.000
M91-M94 Chondropathies
0.729 0.271 0.000
I73.9 Peripheral vascular disease, unspecified
0.728 0.272 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.728 0.272 0.000
M13.94 Arthritis, unspecified (Hand)
0.728 0.272 0.000
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.727 0.272 0.000
H02 Other disorders of eyelid
0.727 0.273 0.000
Z09.2 Follow-up examination after chemotherapy for other conditions
0.726 0.274 0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.725 0.275 0.000
D64.9 Anaemia, unspecified
0.724 0.276 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.724 0.276 0.000
F03 Unspecified dementia
0.724 0.276 0.000
E34.9 Endocrine disorder, unspecified
0.724 0.276 0.000
H26 Other cataract
0.724 0.276 0.000
S20-S29 Injuries to the thorax
0.724 0.276 0.000
E00-E07 Disorders of thyroid gland
0.721 0.279 0.000
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes
0.720 0.280 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.720 0.280 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.719 0.281 0.000
S70-S79 Injuries to the hip and thigh
0.719 0.281 0.000
M40-M43 Deforming dorsopathies
0.718 0.282 0.000
H40 Glaucoma
0.718 0.282 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.717 0.283 0.000
S81 Open wound of lower leg
0.717 0.283 0.000
E27 Other disorders of adrenal gland
0.717 0.283 0.000
Z89 Acquired absence of limb
0.717 0.283 0.000
Z84 Family history of other conditions
0.717 0.283 0.000
Z81 Family history of mental and behavioural disorders
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Z54 Convalescence
0.717 0.283 0.000
Z52 Donors of organs and tissues
0.717 0.283 0.000
Z44 Fitting and adjustment of external prosthetic device
0.717 0.283 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
A41 Other septicaemia
0.717 0.283 0.000
E40-E46 Malnutrition
0.716 0.283 0.000
T79-T79 Certain early complications of trauma
0.716 0.284 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.716 0.284 0.000
F80-F89 Disorders of psychological development
0.716 0.284 0.000
F70-F79 Mental retardation
0.716 0.284 0.000
F60-F69 Disorders of adult personality and behaviour
0.716 0.284 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.716 0.284 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.716 0.284 0.000
Z76 Persons encountering health services in other circumstances
0.716 0.284 0.000
Z70 Counselling related to sexual attitude, behaviour and orientation
0.716 0.284 0.000
Z92.9 Personal history of medical treatment, unspecified
0.715 0.285 0.000
Z92.8 Personal history of other medical treatment
0.715 0.285 0.000
Z92.5 Personal history of rehabilitation measures
0.715 0.285 0.000
Z51.9 Medical care, unspecified
0.715 0.285 0.000
Z51.6 Desensitisation to allergens
0.715 0.285 0.000
V10-V19 Pedal cyclist injured in transport accident
0.715 0.285 0.000
Z29 Need for other prophylactic measures
0.714 0.285 0.000
B99-B99 Other infectious diseases
0.713 0.287 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.713 0.287 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.713 0.287 0.000
B65-B83 Helminthiases
0.713 0.287 0.000
B50-B64 Protozoal diseases
0.713 0.287 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.713 0.287 0.000
B15-B19 Viral hepatitis
0.713 0.287 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.713 0.287 0.000
A75-A79 Rickettsioses
0.713 0.287 0.000
A70-A74 Other diseases caused by chlamydiae
0.713 0.287 0.000
A65-A69 Other spirochaetal diseases
0.713 0.287 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.713 0.287 0.000
A20-A28 Certain zoonotic bacterial diseases
0.713 0.287 0.000
A15-A19 Tuberculosis
0.713 0.287 0.000
R30-R39 Symptoms and signs involving the urinary system
0.713 0.287 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.713 0.287 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.713 0.287 0.000
M48.0 Spinal stenosis
0.713 0.287 0.000
Z73.9 Problem related to life-management difficulty, unspecified
0.713 0.287 0.000
Z74 Problems related to care-provider dependency
0.713 0.287 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.713 0.287 0.000
E50-E64 Other nutritional deficiencies
0.712 0.288 0.000
E85 Amyloidosis
0.712 0.288 0.000
E84 Cystic fibrosis
0.712 0.288 0.000
E79 Disorders of purine and pyrimidine metabolism
0.712 0.288 0.000
E77 Disorders of glycoprotein metabolism
0.712 0.288 0.000
E76 Disorders of glycosaminoglycan metabolism
0.712 0.288 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.712 0.288 0.000
E74 Other disorders of carbohydrate metabolism
0.712 0.288 0.000
E73 Lactose intolerance
0.712 0.288 0.000
E72 Other disorders of amino-acid metabolism
0.712 0.288 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.712 0.288 0.000
E70 Disorders of aromatic amino-acid metabolism
0.712 0.288 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.712 0.288 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.711 0.288 0.000
M00-M03 Infectious arthropathies
0.711 0.288 0.000
Z72.9 Problem related to lifestyle, unspecified
0.711 0.288 0.000
Z72.8 Other problems related to lifestyle
0.711 0.288 0.000
Z72.6 Gambling and betting
0.711 0.288 0.000
Z72.5 High-risk sexual behaviour
0.711 0.288 0.000
Z72.4 Inappropriate diet and eating habits
0.711 0.288 0.000
Z72.3 Lack of physical exercise
0.711 0.288 0.000
R74 Abnormal serum enzyme levels
0.711 0.289 0.000
H35 Other retinal disorders
0.710 0.290 0.000
Z86.3 Personal history of endocrine, nutritional and metabolic diseases
0.710 0.290 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.710 0.290 0.000
F33 Recurrent depressive disorder
0.709 0.291 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.709 0.291 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.709 0.291 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.708 0.292 0.000
E87.4 Mixed disorder of acid-base balance
0.708 0.292 0.000
E87.3 Alkalosis
0.708 0.292 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.708 0.292 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.708 0.292 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.708 0.292 0.000
M05 Seropositive rheumatoid arthritis
0.708 0.292 0.000
Z41 Procedures for purposes other than remedying health state
0.708 0.292 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.707 0.293 0.000
Z51.8 Other specified medical care
0.707 0.293 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.707 0.293 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.706 0.294 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.706 0.294 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.706 0.294 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.706 0.294 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.706 0.294 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.706 0.294 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.706 0.294 0.000
F11 Mental and behavioural disorders due to use of opioids
0.706 0.294 0.000
G40-G47 Episodic and paroxysmal disorders
0.706 0.294 0.000
Z83.5 Family history of eye and ear disorders
0.706 0.294 0.000
D63.8 Anaemia in other chronic diseases classified elsewhere
0.706 0.294 0.000
H04 Disorders of lachrymal system
0.706 0.294 0.000
I88 Nonspecific lymphadenitis
0.706 0.294 0.000
I86 Varicose veins of other sites
0.706 0.294 0.000
F10.2 Dependence syndrome
0.706 0.294 0.000
M80-M85 Disorders of bone density and structure
0.705 0.295 0.000
Z45 Adjustment and management of implanted device
0.705 0.295 0.000
Z50.6 Orthoptic training
0.704 0.296 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.704 0.296 0.000
Z50.3 Drug rehabilitation
0.704 0.296 0.000
T87 Complications peculiar to reattachment and amputation
0.704 0.296 0.000
T86 Failure and rejection of transplanted organs and tissues
0.704 0.296 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.704 0.296 0.000
Y52 Agents primarily affecting the cardiovascular system
0.704 0.296 0.000
S80.9 Superficial injury of lower leg, unspecified
0.703 0.297 0.000
M14 Arthropathies in other diseases classified elsewhere
0.703 0.297 0.000
M12 Other specific arthropathies
0.703 0.297 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.703 0.297 0.000
M08 Juvenile arthritis
0.703 0.297 0.000
M07 Psoriatic and enteropathic arthropathies
0.703 0.297 0.000
S89 Other and unspecified injuries of lower leg
0.702 0.298 0.000
E83.5 Disorders of calcium metabolism
0.702 0.298 0.000
Z93.5 Cystostomy status
0.701 0.299 0.000
E28 Ovarian dysfunction
0.700 0.300 0.000
L60-L75 Disorders of skin appendages
0.700 0.300 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.700 0.300 0.000
F10.9 Unspecified mental and behavioural disorder
0.699 0.301 0.000
F10.8 Other mental and behavioural disorders
0.699 0.301 0.000
F10.7 Residual and late-onset psychotic disorder
0.699 0.301 0.000
F10.6 Amnesic syndrome
0.699 0.301 0.000
F10.5 Psychotic disorder
0.699 0.301 0.000
F10.4 Withdrawal state with delirium
0.699 0.301 0.000
Z10 Routine general health check-up of defined subpopulation
0.699 0.301 0.000
S00.8 Superficial injury of other parts of head
0.699 0.301 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.698 0.302 0.000
F29 Unspecified nonorganic psychosis
0.698 0.302 0.000
Z93.0 Tracheostomy status
0.698 0.302 0.000
Chapter X Diseases of the respiratory system
0.697 0.303 0.000
G70-G73 Diseases of myoneural junction and muscle
0.697 0.303 0.000
M70-M79 Other soft tissue disorders
0.696 0.304 0.000
Z46 Fitting and adjustment of other devices
0.696 0.304 0.000
S06 Intracranial injury
0.696 0.304 0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.696 0.304 0.000
C77.8 Lymph nodes of multiple regions
0.695 0.305 0.000
L81 Other disorders of pigmentation
0.693 0.307 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.692 0.307 0.000
I34.0 Mitral (valve) insufficiency
0.692 0.308 0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.692 0.308 0.000
F10.0 Acute intoxication
0.692 0.308 0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.692 0.308 0.000
M13.8 Other specified arthritis
0.691 0.309 0.000
M13.1 Monoarthritis, not elsewhere classified
0.691 0.309 0.000
M13.0 Polyarthritis, unspecified
0.691 0.309 0.000
G93.6 Cerebral oedema
0.690 0.310 0.000
I50 Heart failure
0.690 0.310 0.000
F38 Other mood [affective] disorders
0.689 0.310 0.000
F34 Persistent mood [affective] disorders
0.689 0.310 0.000
F30 Manic episode
0.689 0.310 0.000
F39 Unspecified mood [affective] disorder
0.689 0.310 0.000
H21 Other disorders of iris and ciliary body
0.689 0.311 0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)
0.689 0.311 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.688 0.312 0.000
E21.0 Primary hyperparathyroidism
0.688 0.312 0.000
F01 Vascular dementia
0.688 0.312 0.000
W20-W49 Exposure to inanimate mechanical forces
0.687 0.313 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.687 0.313 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.687 0.313 0.000
Z96.0 Presence of urogenital implants
0.686 0.314 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.685 0.315 0.000
E32 Diseases of thymus
0.685 0.315 0.000
E31 Polyglandular dysfunction
0.685 0.315 0.000
E30 Disorders of puberty, not elsewhere classified
0.685 0.315 0.000
E26 Hyperaldosteronism
0.685 0.315 0.000
E25 Adrenogenital disorders
0.685 0.315 0.000
E24 Cushing's syndrome
0.685 0.315 0.000
E20 Hypoparathyroidism
0.685 0.315 0.000
D00-D09 In situ neoplasms
0.684 0.315 0.000
A02 Other Salmonella infections
0.684 0.316 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.683 0.317 0.000
M13.93 Arthritis, unspecified (Forearm)
0.683 0.317 0.000
M13.92 Arthritis, unspecified (Upper arm)
0.683 0.317 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.682 0.317 0.000
X60-X84 Intentional self-harm
0.682 0.318 0.000
I52 Other heart disorders in diseases classified elsewhere
0.681 0.319 0.000
I48 Atrial fibrillation and flutter
0.681 0.319 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.681 0.319 0.000
I41 Myocarditis in diseases classified elsewhere
0.681 0.319 0.000
I40 Acute myocarditis
0.681 0.319 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.681 0.319 0.000
I37 Pulmonary valve disorders
0.681 0.319 0.000
I36 Nonrheumatic tricuspid valve disorders
0.681 0.319 0.000
I32 Pericarditis in diseases classified elsewhere
0.681 0.319 0.000
I30 Acute pericarditis
0.681 0.319 0.000
T85.2 Mechanical complication of intraocular lens
0.680 0.320 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.680 0.320 0.000
Z42.0 Follow-up care involving plastic surgery of head and neck
0.679 0.320 0.000
Z88.4 Personal history of allergy to anaesthetic agent
0.679 0.321 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.678 0.322 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.678 0.322 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.678 0.322 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.678 0.322 0.000
I33 Acute and subacute endocarditis
0.678 0.322 0.000
I77 Other disorders of arteries and arterioles
0.678 0.322 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.678 0.322 0.000
D55-D59 Haemolytic anaemias
0.678 0.322 0.000
F00 Dementia in Alzheimer's disease
0.677 0.323 0.000
C77.2 Intra-abdominal lymph nodes
0.677 0.323 0.000
Z03.1 Observation for suspected malignant neoplasm
0.677 0.323 0.000
I85 Oesophageal varices
0.676 0.324 0.000
Z91.6 Personal history of other physical trauma
0.676 0.324 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.675 0.324 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.675 0.324 0.000
C79.6 Secondary malignant neoplasm of ovary
0.675 0.324 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.675 0.324 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.675 0.324 0.000
S88 Traumatic amputation of lower leg
0.675 0.325 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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