TreeWAS – Variant ID: rs28376053

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability
E11.9 Without complications	0.998	0.002
Z86 Personal history of certain other diseases	0.998	0.002
Z86.4 Personal history of psychoactive substance abuse	0.997	0.003
Z86.0 Personal history of other neoplasms	0.997	0.003
Z86.7 Personal history of diseases of the circulatory system	0.996	0.004
E11 Non-insulin-dependent diabetes mellitus	0.993	0.007
E11.4 With neurological complications	0.938	0.062
E11.2 With renal complications	0.910	0.090
E11.0 With coma	0.890	0.110
E10-E14 Diabetes mellitus	0.888	0.112
E14 Unspecified diabetes mellitus	0.854	0.146
Z86.3 Personal history of endocrine, nutritional and metabolic diseases	0.848	0.152
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.806	0.194
Z86.6 Personal history of diseases of the nervous system and sense organs	0.801	0.199
E11.8 With unspecified complications	0.739	0.261
E14.4 With neurological complications	0.734	0.266
E11.3 With ophthalmic complications	0.720	0.280
E11.7 With multiple complications	0.712	0.288
E14.9 Without complications	0.707	0.293
E11.1 With ketoacidosis	0.699	0.301
E14.3 With ophthalmic complications	0.695	0.305
E14.6 With other specified complications	0.680	0.320
Chapter IV Endocrine, nutritional and metabolic diseases	0.672	0.328
E05 Thyrotoxicosis [hyperthyroidism]	0.669	0.331
E00-E07 Disorders of thyroid gland	0.664	0.336
E05.0 Thyrotoxicosis with diffuse goitre	0.662	0.338
E14.2 Withrenal complications	0.655	0.345
E11.5 With peripheral circulatory complications	0.646	0.353
E14.1 With ketoacidosis	0.646	0.354
E05.9 Thyrotoxicosis, unspecified	0.638	0.362
E12 Malnutrition-related diabetes mellitus	0.637	0.363
E13 Other specified diabetes mellitus	0.615	0.385
E06 Thyroiditis	0.614	0.386
E14.8 With unspecified complications	0.612	0.388
E14.7 With multiple complications	0.612	0.388
E14.5 With peripheral circulatory complications	0.612	0.388
E14.0 With coma	0.612	0.388
E11.6 With other specified complications	0.599	0.401
E06.3 Autoimmune thyroiditis	0.546	0.454
E50-E64 Other nutritional deficiencies	0.531	0.469
E65-E68 Obesity and other hyperalimentation	0.527	0.473
E06.9 Thyroiditis, unspecified	0.522	0.478
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.493	0.507
E05.5 Thyroid crisis or storm	0.479	0.520
E05.4 Thyrotoxicosis factitia	0.479	0.520
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.479	0.520
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.479	0.520
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.476	0.524
E00 Congenital iodine-deficiency syndrome	0.476	0.524
E02 Subclinical iodine-deficiency hypothyroidism	0.476	0.524
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.476	0.524
E61 Deficiency of other nutrient elements	0.472	0.528
E05.8 Other thyrotoxicosis	0.465	0.535
E12.9 Without complications	0.457	0.543
E12.8 With unspecified complications	0.457	0.543
E12.7 With multiple complications	0.457	0.543
E12.6 With other specified complications	0.457	0.543
E12.5 With peripheral circulatory complications	0.457	0.543
E12.4 With neurological complications	0.457	0.543
E12.3 With ophthalmic complications	0.457	0.543
E12.2 With renal complications	0.457	0.543
E12.1 With ketoacidosis	0.457	0.543
E12.0 With coma	0.457	0.543
E13.8 With unspecified complications	0.441	0.559
E13.7 With multiple complications	0.441	0.559
E13.6 With other specified complications	0.441	0.559
E13.5 With peripheral circulatory complications	0.441	0.559
E13.4 With neurological complications	0.441	0.559
E13.3 With ophthalmic complications	0.441	0.559
E13.2 With renal complications	0.441	0.559
E13.1 With ketoacidosis	0.441	0.559
E13.0 With coma	0.441	0.559
E06.5 Other chronic thyroiditis	0.440	0.560
E06.4 Drug-induced thyroiditis	0.440	0.560
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.440	0.560
E06.1 Subacute thyroiditis	0.440	0.560
E06.0 Acute thyroiditis	0.440	0.560
E65 Localised adiposity	0.429	0.570
E61.1 Iron deficiency	0.428	0.572
E13.9 Without complications	0.419	0.581
E40-E46 Malnutrition	0.408	0.592
E51 Thiamine deficiency	0.400	0.600
E64 Sequelae of malnutrition and other nutritional deficiencies	0.380	0.619
E63 Other nutritional deficiencies	0.380	0.619
E56 Other vitamin deficiencies	0.380	0.619
E50 Vitamin A deficiency	0.380	0.619
E60 Dietary zinc deficiency	0.380	0.619
E59 Dietary selenium deficiency	0.380	0.619
E58 Dietary calcium deficiency	0.380	0.619
E54 Ascorbic acid deficiency	0.380	0.619
E52 Niacin deficiency [pellagra]	0.380	0.619
E67 Other hyperalimentation	0.378	0.622
E68 Sequelae of hyperalimentation	0.378	0.622
E66 Obesity	0.367	0.633
E16 Other disorders of pancreatic internal secretion	0.365	0.635
E15 Nondiabetic hypoglycaemic coma	0.353	0.646
E61.2 Magnesium deficiency	0.346	0.654
J84.1 Other interstitial pulmonary diseases with fibrosis	0.344	0.656
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.341	0.658
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.341	0.658
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.341	0.658
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.341	0.658
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.341	0.658
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.341	0.658
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.341	0.658
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.341	0.658
E61.9 Deficiency of nutrient element, unspecified	0.339	0.661
E61.8 Deficiency of other specified nutrient elements	0.339	0.661
E61.7 Deficiency of multiple nutrient elements	0.339	0.661
E61.6 Vanadium deficiency	0.339	0.661
E61.5 Molybdenum deficiency	0.339	0.661
E61.4 Chromium deficiency	0.339	0.661
E61.3 Manganese deficiency	0.339	0.661
E61.0 Copper deficiency	0.339	0.661
J84.9 Interstitial pulmonary disease, unspecified	0.338	0.662
J84 Other interstitial pulmonary diseases	0.337	0.663
E53 Deficiency of other B group vitamins	0.335	0.665
E66.9 Obesity, unspecified	0.335	0.665
E07 Other disorders of thyroid	0.333	0.667
E51.2 Wernicke's encephalopathy	0.306	0.694
E55 Vitamin D deficiency	0.302	0.698
E16.1 Other hypoglycaemia	0.298	0.702
E10 Insulin-dependent diabetes mellitus	0.298	0.702
E44 Protein-energy malnutrition of moderate and mild degree	0.292	0.707
E45 Retarded development following protein-energy malnutrition	0.292	0.707
E43 Unspecified severe protein-energy malnutrition	0.292	0.707
E42 Marasmic kwashiorkor	0.292	0.707
E41 Nutritional marasmus	0.292	0.707
E40 Kwashiorkor	0.292	0.707
E51.9 Thiamine deficiency, unspecified	0.287	0.713
E51.8 Other manifestations of thiamine deficiency	0.287	0.713
E51.1 Beriberi	0.287	0.713
E50.9 Vitamin A deficiency, unspecified	0.273	0.727
E50.8 Other manifestations of vitamin A deficiency	0.273	0.727
E50.7 Other ocular manifestations of vitamin A deficiency	0.273	0.727
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.273	0.727
E50.5 Vitamin A deficiency with night blindness	0.273	0.727
E50.4 Vitamin A deficiency with keratomalacia	0.273	0.727
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.273	0.727
E50.2 Vitamin A deficiency with corneal xerosis	0.273	0.727
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.273	0.727
E50.0 Vitamin A deficiency with conjunctival xerosis	0.273	0.727
E56.9 Vitamin deficiency, unspecified	0.273	0.727
E56.8 Deficiency of other vitamins	0.273	0.727
E56.1 Deficiency of vitamin K	0.273	0.727
E56.0 Deficiency of vitamin E	0.273	0.727
E63.9 Nutritional deficiency, unspecified	0.273	0.727
E63.8 Other specified nutritional deficiencies	0.273	0.727
E63.1 Imbalance of constituents of food intake	0.273	0.727
E63.0 Essential fatty acid [EFA] deficiency	0.273	0.727
E64.9 Sequelae of unspecified nutritional deficiency	0.273	0.727
E64.8 Sequelae of other nutritional deficiencies	0.273	0.727
E64.3 Sequelae of rickets	0.273	0.727
E64.2 Sequelae of vitamin C deficiency	0.273	0.727
E64.1 Sequelae of vitamin A deficiency	0.273	0.727
E64.0 Sequelae of protein-energy malnutrition	0.273	0.727
E67.8 Other specified hyperalimentation	0.271	0.729
E67.3 Hypervitaminosis D	0.271	0.729
E67.2 Megavitamin-B6 syndrome	0.271	0.729
E67.1 Hypercarotenaemia	0.271	0.729
E67.0 Hypervitaminosis A	0.271	0.729
E66.1 Drug-induced obesity	0.263	0.737
E16.9 Disorder of pancreatic internal secretion, unspecified	0.262	0.738
E16.8 Other specified disorders of pancreatic internal secretion	0.262	0.738
E16.4 Abnormal secretion of gastrin	0.262	0.738
E16.3 Increased secretion of glucagon	0.262	0.738
E10.2 With renal complications	0.260	0.740
E66.2 Extreme obesity with alveolar hypoventilation	0.257	0.743
E16.2 Hypoglycaemia, unspecified	0.244	0.756
J84.8 Other specified interstitial pulmonary diseases	0.243	0.756
E16.0 Drug-induced hypoglycaemia without coma	0.243	0.757
J84.0 Alveolar and parietoalveolar conditions	0.242	0.758
E53.1 Pyridoxine deficiency	0.240	0.759
E53.0 Riboflavin deficiency	0.240	0.759
E07.1 Dyshormogenetic goitre	0.239	0.761
E07.0 Hypersecretion of calcitonin	0.239	0.761
E03 Other hypothyroidism	0.237	0.763
E07.8 Other specified disorders of thyroid	0.227	0.773
E53.8 Deficiency of other specified B group vitamins	0.223	0.777
E10.1 With ketoacidosis	0.221	0.779
E46 Unspecified protein-energy malnutrition	0.218	0.781
E53.9 Vitamin B deficiency, unspecified	0.217	0.783
E55.0 Rickets, active	0.217	0.783
E10.7 With multiple complications	0.214	0.786
E66.0 Obesity due to excess calories	0.213	0.787
E20-E35 Disorders of other endocrine glands	0.212	0.787
E44.1 Mild protein-energy malnutrition	0.210	0.790
E44.0 Moderate protein-energy malnutrition	0.210	0.790
E10.5 With peripheral circulatory complications	0.210	0.790
E10.0 With coma	0.206	0.794
E10.4 With neurological complications	0.204	0.796
E10.6 With other specified complications	0.203	0.797
E10.8 With unspecified complications	0.199	0.801
E20 Hypoparathyroidism	0.176	0.824
E28 Ovarian dysfunction	0.173	0.827
E03.5 Myxoedema coma	0.170	0.830
E03.4 Atrophy of thyroid (acquired)	0.170	0.830
E03.3 Postinfectious hypothyroidism	0.170	0.830
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.170	0.830
E03.1 Congenital hypothyroidism without goitre	0.170	0.830
E03.0 Congenital hypothyroidism with diffuse goitre	0.170	0.830
E34 Other endocrine disorders	0.168	0.832
Z86.5 Personal history of other mental and behavioural disorders	0.162	0.837
E29 Testicular dysfunction	0.153	0.847
E34.0 Carcinoid syndrome	0.153	0.847
E35 Disorders of endocrine glands in diseases classified elsewhere	0.152	0.847
E32 Diseases of thymus	0.152	0.847
E31 Polyglandular dysfunction	0.152	0.847
E30 Disorders of puberty, not elsewhere classified	0.152	0.847
E25 Adrenogenital disorders	0.152	0.847
E20.9 Hypoparathyroidism, unspecified	0.151	0.849
E03.8 Other specified hypothyroidism	0.150	0.850
J80-J84 Other respiratory diseases principally affecting the interstitium	0.145	0.855
Chapter XX External causes of morbidity and mortality	0.141	0.859
E55.9 Vitamin D deficiency, unspecified	0.138	0.861
E66.8 Other obesity	0.138	0.862
E28.3 Primary ovarian failure	0.137	0.863
E28.2 Polycystic ovarian syndrome	0.133	0.867
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.132	0.868
W20-W49 Exposure to inanimate mechanical forces	0.131	0.869
X40-X49 Accidental poisoning by and exposure to noxious substances	0.130	0.870
E26 Hyperaldosteronism	0.128	0.872
Y95 Nosocomial condition	0.127	0.873
E24 Cushing's syndrome	0.127	0.873
E20.8 Other hypoparathyroidism	0.127	0.873
E20.1 Pseudohypoparathyroidism	0.127	0.873
E20.0 Idiopathic hypoparathyroidism	0.127	0.873
X60-X84 Intentional self-harm	0.125	0.875
# Top node	0.125	0.875
E28.9 Ovarian dysfunction, unspecified	0.124	0.876
E28.8 Other ovarian dysfunction	0.124	0.876
E28.1 Androgen excess	0.124	0.876
E28.0 Oestrogen excess	0.124	0.876
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.123	0.877
Chapter X Diseases of the respiratory system	0.123	0.877
E07.9 Disorder of thyroid, unspecified	0.122	0.877
E23 Hypofunction and other disorders of pituitary gland	0.122	0.878
E34.5 Androgen resistance syndrome	0.120	0.879
E34.4 Constitutional tall stature	0.120	0.879
E34.3 Short stature, not elsewhere classified	0.120	0.879
E34.2 Ectopic hormone secretion, not elsewhere classified	0.120	0.879
E34.1 Other hypersecretion of intestinal hormones	0.120	0.879
Y00-Y09 Assault	0.119	0.881
Z86.1 Personal history of infectious and parasitic diseases	0.118	0.882
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.117	0.882
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.117	0.883
W50-W64 Exposure to animate mechanical forces	0.117	0.883
W44 Foreign body entering into or through eye or natural orifice	0.116	0.884
Q80-Q89 Other congenital malformations	0.116	0.884
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.114	0.886
J60-J70 Lung diseases due to external agents	0.112	0.888
X20-X29 Contact with venomous animals and plants	0.112	0.888
Chapter XXII Codes for special purposes	0.112	0.888
X58-X59 Accidental exposure to other and unspecified factors	0.111	0.889
E29.1 Testicular hypofunction	0.111	0.889
Chapter V Mental and behavioural disorders	0.110	0.890
E29.9 Testicular dysfunction, unspecified	0.110	0.890
E29.8 Other testicular dysfunction	0.110	0.890
E29.0 Testicular hyperfunction	0.110	0.890
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.110	0.890
E25.9 Adrenogenital disorder, unspecified	0.109	0.890
E25.8 Other adrenogenital disorders	0.109	0.890
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.109	0.890
E30.9 Disorder of puberty, unspecified	0.109	0.890
E30.8 Other disorders of puberty	0.109	0.890
E30.1 Precocious puberty	0.109	0.890
E30.0 Delayed puberty	0.109	0.890
E31.9 Polyglandular dysfunction, unspecified	0.109	0.890
E31.8 Other polyglandular dysfunction	0.109	0.890
E31.1 Polyglandular hyperfunction	0.109	0.890
E31.0 Autoimmune polyglandular failure	0.109	0.890
E32.9 Disease of thymus, unspecified	0.109	0.890
E32.8 Other diseases of thymus	0.109	0.890
E32.1 Abscess of thymus	0.109	0.890
E32.0 Persistent hyperplasia of thymus	0.109	0.890
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.109	0.890
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.109	0.890
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.109	0.890
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.110	0.890
X00-X09 Exposure to smoke, fire and flames	0.110	0.890
Q85 Phakomatoses, not elsewhere classified	0.109	0.891
W75-W84 Other accidental threats to breathing	0.109	0.891
W20 Struck by thrown, projected or falling object	0.108	0.891
Y10-Y34 Event of undetermined intent	0.108	0.892
X50-X57 Overexertion, travel and privation	0.108	0.892
X49 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances	0.108	0.892
V10-V19 Pedal cyclist injured in transport accident	0.107	0.893
Q38-Q45 Other congenital malformations of the digestive system	0.106	0.894
V98-V99 Other and unspecified transport accidents	0.106	0.894
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.105	0.895
F31 Bipolar affective disorder	0.105	0.895
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.105	0.895
E34.8 Other specified endocrine disorders	0.105	0.895
W44.0 Home	0.105	0.895
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.105	0.895
C20 Malignant neoplasm of rectum	0.105	0.895
F30-F39 Mood [affective] disorders	0.104	0.896
C79 Secondary malignant neoplasm of other sites	0.104	0.896
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.103	0.897
Chapter II Neoplasms	0.103	0.897
J90-J94 Other diseases of pleura	0.103	0.897
X45 Accidental poisoning by and exposure to alcohol	0.103	0.897
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.102	0.898
V01-V09 Pedestrian injured in transport accident	0.102	0.898
Q85.0 Neurofibromatosis (nonmalignant)	0.102	0.898
S20-S29 Injuries to the thorax	0.102	0.898
E22 Hyperfunction of pituitary gland	0.101	0.898
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.102	0.898
Y35-Y36 Legal intervention and operations of war	0.101	0.898
X85-X99 Assault	0.101	0.898
X30-X39 Exposure to forces of nature	0.101	0.898
W65-W74 Accidental drowning and submersion	0.101	0.898
V95-V97 Air and space transport accidents	0.101	0.898
V90-V94 Water transport accidents	0.101	0.898
V70-V79 Bus occupant injured in transport accident	0.101	0.898
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.101	0.898
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.101	0.898
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.101	0.899
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system	0.101	0.899
X47 Accidental poisoning by and exposure to other gases and vapours	0.101	0.899
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified	0.101	0.899
W26 Contact with knife, sword or dagger	0.101	0.899
E04 Other non-toxic goitre	0.100	0.900
V40-V49 Car occupant injured in transport accident	0.100	0.900
C15-C26 Malignant neoplasms of digestive organs	0.100	0.900
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.099	0.901
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.099	0.901
W22 Striking against or struck by other objects	0.099	0.901
X69 Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances	0.099	0.901
Y60-Y69 Misadventures to patients during surgical and medical care	0.099	0.901
Q74 Other congenital malformations of limb(s)	0.099	0.901
W23 Caught, crushed, jammed or pinched in or between objects	0.098	0.902
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.098	0.902
X60 Intentional self-poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics	0.098	0.902
E23.6 Other disorders of pituitary gland	0.098	0.902
J91 Pleural effusion in conditions classified elsewhere	0.098	0.902
Y00 Assault by blunt object	0.097	0.903
X42 Accidental poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified	0.097	0.903
C34 Malignant neoplasm of bronchus and lung	0.097	0.903
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.097	0.903
S27 Injury of other and unspecified intrathoracic organs	0.097	0.903
Q00-Q07 Congenital malformations of the nervous system	0.096	0.903
T90 Sequelae of injuries of head	0.096	0.904
W51 Striking against or bumped into by another person	0.096	0.904
E23.7 Disorder of pituitary gland, unspecified	0.096	0.904
W21 Striking against or struck by sports equipment	0.096	0.904
I25.9 Chronic ischaemic heart disease, unspecified	0.096	0.904
W45 Foreign body or object entering through skin	0.095	0.904
Y04 Assault by bodily force	0.095	0.905
Y76 Obstetric and gynaecological devices associated with adverse incidents	0.095	0.905
Y90 Evidence of alcohol involvement determined by blood alcohol level	0.095	0.905
Y98 Lifestyle-related condition	0.095	0.905
Y97 Environmental-pollution-related condition	0.095	0.905
Y96 Work-related condition	0.095	0.905
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.095	0.905
W27 Contact with nonpowered hand tool	0.095	0.905
W49 Exposure to other and unspecified inanimate mechanical forces	0.095	0.905
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified	0.095	0.905
X58 Exposure to other specified factors	0.094	0.905
V20-V29 Motorcycle rider injured in transport accident	0.094	0.906
X65 Intentional self-poisoning by and exposure to alcohol	0.094	0.906
J67 Hypersensitivity pneumonitis due to organic dust	0.094	0.906
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.094	0.906
W46 Contact with hypodermic needle	0.094	0.906
W43 Exposure to vibration	0.094	0.906
W42 Exposure to noise	0.094	0.906
W41 Exposure to high-pressure jet	0.094	0.906
W40 Explosion of other materials	0.094	0.906
W39 Discharge of firework	0.094	0.906
W38 Explosion and rupture of other specified pressurised devices	0.094	0.906
W37 Explosion and rupture of pressurised tyre, pipe or hose	0.094	0.906
W36 Explosion and rupture of gas cylinder	0.094	0.906
W35 Explosion and rupture of boiler	0.094	0.906
W34 Discharge from other and unspecified firearms	0.094	0.906
W33 Rifle, shotgun and larger firearm discharge	0.094	0.906
W32 Handgun discharge	0.094	0.906
W31 Contact with other and unspecified machinery	0.094	0.906
W30 Contact with agricultural machinery	0.094	0.906
W28 Contact with powered lawn mower	0.094	0.906
W24 Contact with lifting and transmission devices, not elsewhere classified	0.094	0.906
W20.8 Other specified place	0.094	0.906
Q66 Congenital deformities of feet	0.093	0.907
Y71 Cardiovascular devices associated with adverse incidents	0.093	0.907
C79.7 Secondary malignant neoplasm of adrenal gland	0.093	0.907
X48 Accidental poisoning by and exposure to pesticides	0.093	0.907
X46 Accidental poisoning by and exposure to organic solvents and halogenated hydrocarbons and their vapours	0.093	0.907
X44 Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances	0.093	0.907
X43 Accidental poisoning by and exposure to other drugs acting on the autonomic nervous system	0.093	0.907
X40 Accidental poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics	0.093	0.907
D06.9 Cervix, unspecified	0.093	0.907
V80-V89 Other land transport accidents	0.093	0.907
Y73 Gastro-enterology and urology devices associated with adverse incidents	0.093	0.907
E34.9 Endocrine disorder, unspecified	0.092	0.907
T15-T19 Effects of foreign body entering through natural orifice	0.092	0.908
E27 Other disorders of adrenal gland	0.092	0.908
U80 Agent resistant to penicillin and related antibiotics	0.092	0.908
E26.9 Hyperaldosteronism, unspecified	0.092	0.908
E26.8 Other hyperaldosteronism	0.092	0.908
E26.1 Secondary hyperaldosteronism	0.092	0.908
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.092	0.908
X23 Contact with hornets, wasps and bees	0.092	0.908
J93 Pneumothorax	0.091	0.909
W50 Hit, struck, kicked, twisted, bitten or scratched by another person	0.091	0.909
E24.8 Other Cushing's syndrome	0.091	0.909
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.091	0.909
E24.3 Ectopic ACTH syndrome	0.091	0.909
E24.1 Nelson's syndrome	0.091	0.909
E24.0 Pituitary-dependent Cushing's disease	0.091	0.909
T91 Sequelae of injuries of neck and trunk	0.091	0.909
C78.7 Secondary malignant neoplasm of liver	0.091	0.909
X67 Intentional self-poisoning by and exposure to other gases and vapours	0.091	0.909
X10-X19 Contact with heat and hot substances	0.091	0.909
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.091	0.909
E24.2 Drug-induced Cushing's syndrome	0.090	0.910
J64 Unspecified pneumoconiosis	0.090	0.910
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.090	0.910
Q65 Congenital deformities of hip	0.090	0.910
F31.9 Bipolar affective disorder, unspecified	0.090	0.910
C34.9 Bronchus or lung, unspecified	0.090	0.910
Q89 Other congenital malformations, not elsewhere classified	0.090	0.910
X84 Intentional self-harm by unspecified means	0.090	0.910
X83 Intentional self-harm by other specified means	0.090	0.910
X82 Intentional self-harm by crashing of motor vehicle	0.090	0.910
X81 Intentional self-harm by jumping or lying before moving object	0.090	0.910
X80 Intentional self-harm by jumping from a high place	0.090	0.910
X79 Intentional self-harm by blunt object	0.090	0.910
X77 Intentional self-harm by steam, hot vapours and hot objects	0.090	0.910
X76 Intentional self-harm by smoke, fire and flames	0.090	0.910
X75 Intentional self-harm by explosive material	0.090	0.910
X74 Intentional self-harm by other and unspecified firearm discharge	0.090	0.910
X73 Intentional self-harm by rifle, shotgun and larger firearm discharge	0.090	0.910
X72 Intentional self-harm by handgun discharge	0.090	0.910
X71 Intentional self-harm by drowning and submersion	0.090	0.910
X70 Intentional self-harm by hanging, strangulation and suffocation	0.090	0.910
X66 Intentional self-poisoning by and exposure to organic solvents and halogenated hydrocarbons and their vapours	0.090	0.910
X64 Intentional self-poisoning by and exposure to other and unspecified drugs, medicaments and biological substances	0.090	0.910
X61 Intentional self-poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified	0.090	0.910
U81 Agent resistant to vancomycin and related antibiotics	0.090	0.910
Chapter XVI Certain conditions originating in the perinatal period	0.090	0.910
J62 Pneumoconiosis due to dust containing silica	0.090	0.910
J70 Respiratory conditions due to other external agents	0.089	0.911
F60-F69 Disorders of adult personality and behaviour	0.089	0.911
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.089	0.911
D06 Carcinoma in situ of cervix uteri	0.089	0.911
Q76 Congenital malformations of spine and bony thorax	0.089	0.911
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.089	0.911
E10.3 With ophthalmic complications	0.089	0.911
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.089	0.911
X49.9 Unspecified place	0.089	0.911
E21.5 Disorder of parathyroid gland, unspecified	0.089	0.911
J95-J99 Other diseases of the respiratory system	0.089	0.911
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.088	0.911
Q35-Q37 Cleft lip and cleft palate	0.088	0.911
Q30-Q34 Congenital malformations of the respiratory system	0.088	0.911
J60 Coalworker's pneumoconiosis	0.088	0.912
W57 Bitten or stung by non-venomous insect and other non-venomous arthropods	0.088	0.912
S27.0 Traumatic pneumothorax	0.088	0.912
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.087	0.912
E23.1 Drug-induced hypopituitarism	0.087	0.912
X68 Intentional self-poisoning by and exposure to pesticides	0.087	0.913
V53 Occupant of pick-up truck or van injured in collision with car, pick-up truck or van	0.087	0.913
S90-S99 Injuries to the ankle and foot	0.087	0.913
Y85 Sequelae of transport accidents	0.087	0.913
X78 Intentional self-harm by sharp object	0.087	0.913
C15 Malignant neoplasm of oesophagus	0.087	0.913
W94 Exposure to high and low air pressure and changes in air pressure	0.087	0.913
X00 Exposure to uncontrolled fire in building or structure	0.087	0.913
D00-D09 In situ neoplasms	0.087	0.913
F80-F89 Disorders of psychological development	0.086	0.914
T90.2 Sequelae of fracture of skull and facial bones	0.086	0.914
X51 Travel and motion	0.086	0.914
Y09 Assault by unspecified means	0.086	0.914
Y08 Assault by other specified means	0.086	0.914
Y07 Other maltreatment syndromes	0.086	0.914
Y06 Neglect and abandonment	0.086	0.914
Y05 Sexual assault by bodily force	0.086	0.914
Y03 Assault by crashing of motor vehicle	0.086	0.914
Y02 Assault by pushing or placing victim before moving object	0.086	0.914
Y01 Assault by pushing from high place	0.086	0.914
T51 Toxic effect of alcohol	0.086	0.914
F31.6 Bipolar affective disorder, current episode mixed	0.086	0.914
Q43 Other congenital malformations of intestine	0.086	0.914
W79 Inhalation and ingestion of food causing obstruction of respiratory tract	0.085	0.914
Q83 Congenital malformations of breast	0.085	0.915
S50-S59 Injuries to the elbow and forearm	0.085	0.915
J00-J06 Acute upper respiratory infections	0.085	0.915
T17 Foreign body in respiratory tract	0.085	0.915
Q85.9 Phakomatosis, unspecified	0.085	0.915
W25 Contact with sharp glass	0.084	0.915
Y82 Other and unspecified medical devices associated with adverse incidents	0.084	0.915
Y81 General- and plastic-surgery devices associated with adverse incidents	0.084	0.915
Y80 Physical medicine devices associated with adverse incidents	0.084	0.915
Y78 Radiological devices associated with adverse incidents	0.084	0.915
Y77 Ophthalmic devices associated with adverse incidents	0.084	0.915
Y75 Neurological devices associated with adverse incidents	0.084	0.915
Y74 General hospital and personal-use devices associated with adverse incidents	0.084	0.915
Y72 Otorhinolaryngological devices associated with adverse incidents	0.084	0.915
Y70 Anaesthesiology devices associated with adverse incidents	0.084	0.915
Y28 Contact with sharp object, undetermined intent	0.084	0.915
Y91 Evidence of alcohol involvement determined by level of intoxication	0.084	0.916

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations