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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2847281
log Bayes Factor = 1.47314
Chromosome 18   position 12,821,593  (GRCh37) Explore rs2847281 on Ensembl!
Variant rs2847281 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.045 0.955
E03 Other hypothyroidism
0.000 0.420 0.580
E03.8 Other specified hypothyroidism
0.000 0.559 0.441
E03.5 Myxoedema coma
0.000 0.584 0.416
E03.4 Atrophy of thyroid (acquired)
0.000 0.584 0.416
E03.3 Postinfectious hypothyroidism
0.000 0.584 0.416
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.584 0.416
E03.1 Congenital hypothyroidism without goitre
0.000 0.585 0.415
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.626 0.374
E00-E07 Disorders of thyroid gland
0.000 0.672 0.328
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.686 0.314
E05.9 Thyrotoxicosis, unspecified
0.000 0.690 0.310
E06 Thyroiditis
0.000 0.751 0.249
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.765 0.235
E00 Congenital iodine-deficiency syndrome
0.000 0.765 0.235
E05.8 Other thyrotoxicosis
0.000 0.766 0.234
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.774 0.225
E05.5 Thyroid crisis or storm
0.000 0.775 0.225
E05.4 Thyrotoxicosis factitia
0.000 0.775 0.225
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.775 0.225
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.775 0.225
E07 Other disorders of thyroid
0.000 0.791 0.208
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.803 0.197
E06.9 Thyroiditis, unspecified
0.000 0.803 0.197
E06.5 Other chronic thyroiditis
0.000 0.814 0.186
E06.3 Autoimmune thyroiditis
0.000 0.819 0.181
E06.4 Drug-induced thyroiditis
0.000 0.821 0.179
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.821 0.179
E06.0 Acute thyroiditis
0.000 0.821 0.179
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.831 0.169
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.831 0.169
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.831 0.169
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.831 0.169
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.831 0.169
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.831 0.169
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.831 0.169
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.831 0.169
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.835 0.165
E06.1 Subacute thyroiditis
0.000 0.839 0.160
E07.1 Dyshormogenetic goitre
0.000 0.850 0.150
E07.0 Hypersecretion of calcitonin
0.000 0.850 0.150
E07.9 Disorder of thyroid, unspecified
0.000 0.853 0.147
G57.6 Lesion of plantar nerve
0.132 0.868 0.000
E07.8 Other specified disorders of thyroid
0.000 0.873 0.127
Y84.0 Cardiac catheterisation
0.065 0.935 0.000
Y84.8 Other medical procedures
0.057 0.943 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.055 0.945 0.000
S00.8 Superficial injury of other parts of head
0.000 0.946 0.054
S00 Superficial injury of head
0.000 0.947 0.053
Y84.6 Urinary catheterisation
0.050 0.950 0.000
S00.0 Superficial injury of scalp
0.000 0.952 0.048
S00.4 Superficial injury of ear
0.000 0.952 0.048
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.000 0.953 0.047
S00.1 Contusion of eyelid and periocular area
0.000 0.953 0.047
K90.0 Coeliac disease
0.000 0.955 0.045
S00.3 Superficial injury of nose
0.000 0.956 0.044
S00.2 Other superficial injuries of eyelid and periocular area
0.000 0.957 0.043
E04 Other non-toxic goitre
0.000 0.958 0.042
S00.7 Multiple superficial injuries of head
0.000 0.959 0.041
K51.4 Pseudopolyposis of colon
0.000 0.959 0.041
Y84.7 Blood-sampling
0.040 0.960 0.000
Y84.5 Insertion of gastric or duodenal sound
0.040 0.960 0.000
Y84.1 Kidney dialysis
0.039 0.961 0.000
Y84.4 Aspiration of fluid
0.039 0.961 0.000
K51 Ulcerative colitis
0.000 0.962 0.038
S00.5 Superficial injury of lip and oral cavity
0.000 0.963 0.037
K50 Crohn's disease [regional enteritis]
0.000 0.963 0.037
K50.8 Other Crohn's disease
0.000 0.964 0.036
Y84.9 Medical procedure, unspecified
0.034 0.966 0.000
K90 Intestinal malabsorption
0.000 0.966 0.034
K51.1 Ulcerative (chronic) ileocolitis
0.000 0.966 0.034
G57 Mononeuropathies of lower limb
0.034 0.966 0.000
Y84.3 Shock therapy
0.033 0.966 0.000
K50.0 Crohn's disease of small intestine
0.000 0.967 0.033
K50-K52 Noninfective enteritis and colitis
0.000 0.967 0.033
K51.5 Mucosal proctocolitis
0.000 0.967 0.033
K90.9 Intestinal malabsorption, unspecified
0.000 0.968 0.032
K51.0 Ulcerative (chronic) enterocolitis
0.000 0.969 0.031
E04.8 Other specified non-toxic goitre
0.000 0.970 0.030
K50.1 Crohn's disease of large intestine
0.000 0.970 0.030
E04.0 Non-toxic diffuse goitre
0.000 0.970 0.030
K50.9 Crohn's disease, unspecified
0.000 0.971 0.029
E10 Insulin-dependent diabetes mellitus
0.000 0.971 0.029
E10.9 Without complications
0.000 0.972 0.028
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.973 0.027
G57.8 Other mononeuropathies of lower limb
0.026 0.974 0.000
E10.3 With ophthalmic complications
0.000 0.974 0.026
K51.3 Ulcerative (chronic) rectosigmoiditis
0.000 0.974 0.026
K51.8 Other ulcerative colitis
0.000 0.974 0.026
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.974 0.026
E10-E14 Diabetes mellitus
0.000 0.975 0.025
G57.9 Mononeuropathy of lower limb, unspecified
0.025 0.975 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.975 0.025
K90.3 Pancreatic steatorrhoea
0.000 0.975 0.024
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.975 0.024
K90.1 Tropical sprue
0.000 0.975 0.024
S83.2 Tear of meniscus, current
0.000 0.976 0.024
G57.4 Lesion of medial popliteal nerve
0.024 0.976 0.000
G57.2 Lesion of femoral nerve
0.024 0.976 0.000
G57.0 Lesion of sciatic nerve
0.024 0.976 0.000
K90.8 Other intestinal malabsorption
0.000 0.976 0.024
K51.9 Ulcerative colitis, unspecified
0.000 0.977 0.023
E10.2 With renal complications
0.000 0.977 0.023
E10.8 With unspecified complications
0.000 0.977 0.023
K51.2 Ulcerative (chronic) proctitis
0.000 0.977 0.023
E13 Other specified diabetes mellitus
0.000 0.978 0.022
E10.6 With other specified complications
0.000 0.978 0.022
G57.3 Lesion of lateral popliteal nerve
0.022 0.978 0.000
S00-S09 Injuries to the head
0.000 0.978 0.022
E10.7 With multiple complications
0.000 0.978 0.022
E04.2 Non-toxic multinodular goitre
0.000 0.978 0.022
E10.4 With neurological complications
0.000 0.978 0.022
S01 Open wound of head
0.000 0.979 0.021
S01.2 Open wound of nose
0.000 0.979 0.021
E10.1 With ketoacidosis
0.000 0.980 0.020
S01.1 Open wound of eyelid and periocular area
0.000 0.980 0.020
E13.9 Without complications
0.000 0.980 0.020
G57.1 Meralgia paraesthetica
0.019 0.981 0.000
E40-E46 Malnutrition
0.000 0.981 0.019
M89.97 Disorder of bone, unspecified (Ankle and foot)
0.000 0.981 0.019
S01.4 Open wound of cheek and temporomandibular area
0.000 0.981 0.019
G57.5 Tarsal tunnel syndrome
0.019 0.981 0.000
E12 Malnutrition-related diabetes mellitus
0.000 0.982 0.018
S01.9 Open wound of head, part unspecified
0.000 0.982 0.018
E10.5 With peripheral circulatory complications
0.000 0.982 0.018
E10.0 With coma
0.000 0.983 0.017
E20-E35 Disorders of other endocrine glands
0.000 0.983 0.017
E13.3 With ophthalmic complications
0.000 0.983 0.017
E29.1 Testicular hypofunction
0.000 0.983 0.017
S01.7 Multiple open wounds of head
0.000 0.983 0.017
S03 Dislocation, sprain and strain of joints and ligaments of head
0.000 0.983 0.017
E29 Testicular dysfunction
0.000 0.983 0.016
E50-E64 Other nutritional deficiencies
0.000 0.984 0.016
E13.8 With unspecified complications
0.000 0.984 0.016
E13.7 With multiple complications
0.000 0.984 0.016
E13.6 With other specified complications
0.000 0.984 0.016
E13.5 With peripheral circulatory complications
0.000 0.984 0.016
E13.4 With neurological complications
0.000 0.984 0.016
E13.2 With renal complications
0.000 0.984 0.016
E13.1 With ketoacidosis
0.000 0.984 0.016
E13.0 With coma
0.000 0.984 0.016
S09 Other and unspecified injuries of head
0.000 0.984 0.016
S07 Crushing injury of head
0.000 0.984 0.016
S04 Injury of cranial nerves
0.000 0.984 0.016
B37.9 Candidiasis, unspecified
0.000 0.984 0.016
S06 Intracranial injury
0.000 0.984 0.016
S08 Traumatic amputation of part of head
0.000 0.985 0.015
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.985 0.015
E34 Other endocrine disorders
0.000 0.985 0.015
S01.5 Open wound of lip and oral cavity
0.000 0.985 0.015
E34.0 Carcinoid syndrome
0.000 0.986 0.014
S09.8 Other specified injuries of head
0.000 0.986 0.014
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.986 0.014
E45 Retarded development following protein-energy malnutrition
0.000 0.986 0.014
E43 Unspecified severe protein-energy malnutrition
0.000 0.986 0.014
E42 Marasmic kwashiorkor
0.000 0.986 0.014
E41 Nutritional marasmus
0.000 0.986 0.014
E40 Kwashiorkor
0.000 0.986 0.014
S03.2 Dislocation of tooth
0.000 0.986 0.014
N48.4 Impotence of organic origin
0.000 0.986 0.014
E12.9 Without complications
0.000 0.987 0.013
E12.8 With unspecified complications
0.000 0.987 0.013
E12.7 With multiple complications
0.000 0.987 0.013
E12.6 With other specified complications
0.000 0.987 0.013
E12.5 With peripheral circulatory complications
0.000 0.987 0.013
E12.4 With neurological complications
0.000 0.987 0.013
E12.3 With ophthalmic complications
0.000 0.987 0.013
E12.2 With renal complications
0.000 0.987 0.013
E12.1 With ketoacidosis
0.000 0.987 0.013
E12.0 With coma
0.000 0.987 0.013
Y84.2 Radiological procedure and radiotherapy
0.013 0.987 0.000
E22 Hyperfunction of pituitary gland
0.000 0.987 0.013
S06.5 Traumatic subdural haemorrhage
0.000 0.987 0.013
E46 Unspecified protein-energy malnutrition
0.000 0.987 0.013
E58 Dietary calcium deficiency
0.000 0.987 0.013
E56 Other vitamin deficiencies
0.000 0.987 0.013
S06.3 Focal brain injury
0.000 0.987 0.013
S06.4 Epidural haemorrhage
0.000 0.987 0.012
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.988 0.012
E32 Diseases of thymus
0.000 0.988 0.012
E30 Disorders of puberty, not elsewhere classified
0.000 0.988 0.012
S09.0 Injury of blood vessels of head, not elsewhere classified
0.000 0.988 0.012
E26 Hyperaldosteronism
0.000 0.988 0.012
E20 Hypoparathyroidism
0.000 0.988 0.012
E55 Vitamin D deficiency
0.000 0.988 0.012
S03.5 Sprain and strain of joints and ligaments of other and unspecified parts of head
0.000 0.988 0.012
S03.4 Sprain and strain of jaw
0.000 0.988 0.012
S03.3 Dislocation of other and unspecified parts of head
0.000 0.988 0.012
S09.2 Traumatic rupture of ear drum
0.000 0.988 0.012
E29.8 Other testicular dysfunction
0.000 0.988 0.012
E29.0 Testicular hyperfunction
0.000 0.988 0.012
S03.1 Dislocation of septal cartilage of nose
0.000 0.988 0.012
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.988 0.012
E50 Vitamin A deficiency
0.000 0.988 0.012
E60 Dietary zinc deficiency
0.000 0.988 0.012
E59 Dietary selenium deficiency
0.000 0.988 0.012
E52 Niacin deficiency [pellagra]
0.000 0.988 0.012
G99.2 Myelopathy in diseases classified elsewhere
0.000 0.988 0.012
S06.1 Traumatic cerebral oedema
0.000 0.988 0.012
E25 Adrenogenital disorders
0.000 0.988 0.012
E24 Cushing's syndrome
0.000 0.988 0.012
E51 Thiamine deficiency
0.000 0.988 0.012
S05 Injury of eye and orbit
0.000 0.988 0.012
S09.7 Multiple injuries of head
0.000 0.988 0.012
S09.1 Injury of muscle and tendon of head
0.000 0.988 0.012
S04.9 Injury of unspecified cranial nerve
0.000 0.988 0.011
S04.8 Injury of other cranial nerves
0.000 0.988 0.011
S04.7 Injury of accessory nerve
0.000 0.988 0.011
S04.6 Injury of acoustic nerve
0.000 0.988 0.011
S04.5 Injury of facial nerve
0.000 0.988 0.011
S04.4 Injury of abducent nerve
0.000 0.988 0.011
S04.3 Injury of trigeminal nerve
0.000 0.988 0.011
S04.2 Injury of trochlear nerve
0.000 0.988 0.011
S04.1 Injury of oculomotor nerve
0.000 0.988 0.011
S04.0 Injury of optic nerve and pathways
0.000 0.988 0.011
S07.9 Crushing injury of head, part unspecified
0.000 0.988 0.011
S07.8 Crushing injury of other parts of head
0.000 0.988 0.011
S07.1 Crushing injury of skull
0.000 0.988 0.011
S07.0 Crushing injury of face
0.000 0.988 0.011
E22.1 Hyperprolactinaemia
0.000 0.988 0.012
N18.3 Chronic kidney disease, stage 3
0.012 0.988 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.000 0.988 0.012
E31 Polyglandular dysfunction
0.000 0.988 0.011
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)
0.000 0.989 0.011
S06.7 Intracranial injury with prolonged coma
0.000 0.989 0.011
S08.9 Traumatic amputation of unspecified part of head
0.000 0.989 0.011
S08.8 Traumatic amputation of other parts of head
0.000 0.989 0.011
S08.0 Avulsion of scalp
0.000 0.989 0.011
E29.9 Testicular dysfunction, unspecified
0.000 0.989 0.011
S03.0 Dislocation of jaw
0.000 0.989 0.011
E15 Nondiabetic hypoglycaemic coma
0.000 0.989 0.011
E63 Other nutritional deficiencies
0.000 0.989 0.011
E34.5 Androgen resistance syndrome
0.000 0.989 0.011
E34.4 Constitutional tall stature
0.000 0.989 0.011
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.989 0.011
E34.1 Other hypersecretion of intestinal hormones
0.000 0.989 0.011
E34.3 Short stature, not elsewhere classified
0.000 0.989 0.011
E34.8 Other specified endocrine disorders
0.000 0.989 0.011
E54 Ascorbic acid deficiency
0.000 0.989 0.011
S08.1 Traumatic amputation of ear
0.000 0.989 0.011
E61 Deficiency of other nutrient elements
0.000 0.989 0.011
S06.30 Focal brain injury (without open intracranial wound)
0.000 0.989 0.011
S06.9 Intracranial injury, unspecified
0.000 0.989 0.010
E34.9 Endocrine disorder, unspecified
0.000 0.990 0.010
S06.8 Other intracranial injuries
0.000 0.990 0.010
S05.9 Injury of eye and orbit, part unspecified
0.000 0.990 0.010
E65-E68 Obesity and other hyperalimentation
0.000 0.990 0.010
E28 Ovarian dysfunction
0.000 0.990 0.010
S06.40 Epidural haemorrhage (without open intracranial wound)
0.000 0.990 0.010
E44.1 Mild protein-energy malnutrition
0.000 0.990 0.010
E44.0 Moderate protein-energy malnutrition
0.000 0.990 0.010
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.000 0.990 0.010
E53 Deficiency of other B group vitamins
0.000 0.990 0.010
E23 Hypofunction and other disorders of pituitary gland
0.000 0.990 0.010
E56.1 Deficiency of vitamin K
0.000 0.990 0.010
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.990 0.010
E22.8 Other hyperfunction of pituitary gland
0.000 0.990 0.010
E22.0 Acromegaly and pituitary gigantism
0.000 0.990 0.010
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)
0.000 0.990 0.010
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.010 0.990 0.000
Q61.2 Polycystic kidney, adult type
0.010 0.990 0.000
E26.9 Hyperaldosteronism, unspecified
0.000 0.990 0.009
E56.9 Vitamin deficiency, unspecified
0.000 0.991 0.009
E56.8 Deficiency of other vitamins
0.000 0.991 0.009
E56.0 Deficiency of vitamin E
0.000 0.991 0.009
S06.31 Focal brain injury (with open intracranial wound)
0.000 0.991 0.009
S01.8 Open wound of other parts of head
0.000 0.991 0.009
E55.9 Vitamin D deficiency, unspecified
0.000 0.991 0.009
S06.10 Traumatic cerebral oedema (without open intracranial wound)
0.000 0.991 0.009
S06.41 Epidural haemorrhage (with open intracranial wound)
0.000 0.991 0.009
E30.9 Disorder of puberty, unspecified
0.000 0.991 0.009
E30.8 Other disorders of puberty
0.000 0.991 0.009
E30.1 Precocious puberty
0.000 0.991 0.009
E30.0 Delayed puberty
0.000 0.991 0.009
E32.9 Disease of thymus, unspecified
0.000 0.991 0.009
E32.8 Other diseases of thymus
0.000 0.991 0.009
E32.1 Abscess of thymus
0.000 0.991 0.009
E32.0 Persistent hyperplasia of thymus
0.000 0.991 0.009
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.991 0.009
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.991 0.009
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.991 0.009
E26.8 Other hyperaldosteronism
0.000 0.991 0.009
E26.1 Secondary hyperaldosteronism
0.000 0.991 0.009
E55.0 Rickets, active
0.000 0.991 0.009
E20.8 Other hypoparathyroidism
0.000 0.991 0.009
E20.1 Pseudohypoparathyroidism
0.000 0.991 0.009
E20.0 Idiopathic hypoparathyroidism
0.000 0.991 0.009
S05.3 Ocular laceration without prolapse or loss of intraocular tissue
0.000 0.991 0.009
S05.6 Penetrating wound of eyeball without foreign body
0.000 0.991 0.009
E24.8 Other Cushing's syndrome
0.000 0.991 0.009
S05.5 Penetrating wound of eyeball with foreign body
0.000 0.991 0.009
S06.2 Diffuse brain injury
0.000 0.991 0.009
E24.9 Cushing's syndrome, unspecified
0.000 0.991 0.009
E20.9 Hypoparathyroidism, unspecified
0.000 0.991 0.009
E50.9 Vitamin A deficiency, unspecified
0.000 0.991 0.009
E50.8 Other manifestations of vitamin A deficiency
0.000 0.991 0.009
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.991 0.009
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.991 0.009
E50.5 Vitamin A deficiency with night blindness
0.000 0.991 0.009
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.991 0.009
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.991 0.009
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.991 0.009
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.991 0.009
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.991 0.009
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.991 0.009
E64.8 Sequelae of other nutritional deficiencies
0.000 0.991 0.009
E64.3 Sequelae of rickets
0.000 0.991 0.009
E64.2 Sequelae of vitamin C deficiency
0.000 0.991 0.009
E64.1 Sequelae of vitamin A deficiency
0.000 0.991 0.009
E64.0 Sequelae of protein-energy malnutrition
0.000 0.991 0.009
K52.8 Other specified non-infective gastro-enteritis and colitis
0.000 0.991 0.009
E24.2 Drug-induced Cushing's syndrome
0.000 0.991 0.009
S06.11 Traumatic cerebral oedema (with open intracranial wound)
0.000 0.991 0.009
E25.9 Adrenogenital disorder, unspecified
0.000 0.991 0.009
E25.8 Other adrenogenital disorders
0.000 0.991 0.009
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.991 0.009
E24.3 Ectopic ACTH syndrome
0.000 0.991 0.009
E24.1 Nelson's syndrome
0.000 0.991 0.009
K52 Other non-infective gastro-enteritis and colitis
0.000 0.991 0.009
E51.9 Thiamine deficiency, unspecified
0.000 0.991 0.008
E51.8 Other manifestations of thiamine deficiency
0.000 0.991 0.008
E51.1 Beriberi
0.000 0.991 0.008
S05.7 Avulsion of eye
0.000 0.991 0.008
S05.4 Penetrating wound of orbit with or without foreign body
0.000 0.991 0.008
S06.0 Concussion
0.000 0.991 0.008
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)
0.000 0.991 0.009
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)
0.000 0.991 0.008
E31.9 Polyglandular dysfunction, unspecified
0.000 0.991 0.008
E31.8 Other polyglandular dysfunction
0.000 0.991 0.008
E31.1 Polyglandular hyperfunction
0.000 0.991 0.008
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.991 0.008
H21.5 Other adhesions and disruptions of iris and ciliary body
0.000 0.991 0.008
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)
0.000 0.992 0.008
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)
0.000 0.992 0.008
E26.0 Primary hyperaldosteronism
0.000 0.992 0.008
S00.9 Superficial injury of head, part unspecified
0.000 0.992 0.008
S83.6 Sprain and strain of other and unspecified parts of knee
0.000 0.992 0.008
E51.2 Wernicke's encephalopathy
0.000 0.992 0.008
S83.3 Tear of articular cartilage of knee, current
0.000 0.992 0.008
H21.8 Other specified disorders of iris and ciliary body
0.000 0.992 0.008
E63.8 Other specified nutritional deficiencies
0.000 0.992 0.008
E63.1 Imbalance of constituents of food intake
0.000 0.992 0.008
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.992 0.008
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.992 0.008
E23.7 Disorder of pituitary gland, unspecified
0.000 0.992 0.008
Q61.3 Polycystic kidney, unspecified
0.008 0.992 0.000
Q61 Cystic kidney disease
0.008 0.992 0.000
Z57.5 Occupational exposure to toxic agents in other industries
0.000 0.992 0.008
H21 Other disorders of iris and ciliary body
0.000 0.992 0.008
E61.1 Iron deficiency
0.000 0.992 0.008
E61.9 Deficiency of nutrient element, unspecified
0.000 0.992 0.008
E61.8 Deficiency of other specified nutrient elements
0.000 0.992 0.008
E61.7 Deficiency of multiple nutrient elements
0.000 0.992 0.008
E61.6 Vanadium deficiency
0.000 0.992 0.008
E61.5 Molybdenum deficiency
0.000 0.992 0.008
E61.4 Chromium deficiency
0.000 0.992 0.008
E61.3 Manganese deficiency
0.000 0.992 0.008
E61.0 Copper deficiency
0.000 0.992 0.008
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue
0.000 0.992 0.008
S06.91 Intracranial injury, unspecified (with open intracranial wound)
0.000 0.992 0.008
H54.0 Blindness, both eyes
0.000 0.992 0.008
S06.81 Other intracranial injuries (with open intracranial wound)
0.000 0.992 0.008
X62.9 Unspecified place
0.008 0.992 0.000
E31.0 Autoimmune polyglandular failure
0.000 0.992 0.007
E67 Other hyperalimentation
0.000 0.992 0.008
E68 Sequelae of hyperalimentation
0.000 0.992 0.008
E28.9 Ovarian dysfunction, unspecified
0.000 0.992 0.007
E28.8 Other ovarian dysfunction
0.000 0.992 0.007
E28.1 Androgen excess
0.000 0.992 0.007
E28.0 Oestrogen excess
0.000 0.992 0.007
E28.3 Primary ovarian failure
0.000 0.992 0.008
O14.9 Preeclampsia, unspecified
0.008 0.992 0.000
S83.0 Dislocation of patella
0.000 0.992 0.007
E53.1 Pyridoxine deficiency
0.000 0.992 0.007
E53.0 Riboflavin deficiency
0.000 0.992 0.007
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.992 0.007
E23.1 Drug-induced hypopituitarism
0.000 0.992 0.007
E63.9 Nutritional deficiency, unspecified
0.000 0.993 0.007
E24.0 Pituitary-dependent Cushing's disease
0.000 0.993 0.007
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee
0.000 0.993 0.007
O14.0 Moderate preeclampsia
0.007 0.993 0.000
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body
0.000 0.993 0.007
Y42.5 Other oestrogens and progestogens
0.007 0.993 0.000
E23.6 Other disorders of pituitary gland
0.000 0.993 0.007
S83.1 Dislocation of knee
0.000 0.993 0.007
M89.87 Other specified disorders of bone (Ankle and foot)
0.000 0.993 0.007
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee
0.000 0.993 0.007
S06.90 Intracranial injury, unspecified (without open intracranial wound)
0.000 0.993 0.007
E53.9 Vitamin B deficiency, unspecified
0.000 0.993 0.007
H18.9 Disorder of cornea, unspecified
0.000 0.993 0.007
E65 Localised adiposity
0.000 0.993 0.007
Q61.9 Cystic kidney disease, unspecified
0.007 0.993 0.000
S06.21 Diffuse brain injury (with open intracranial wound)
0.000 0.993 0.007
S06.80 Other intracranial injuries (without open intracranial wound)
0.000 0.993 0.007
H21.0 Hyphaema
0.000 0.993 0.007
S01.3 Open wound of ear
0.000 0.993 0.006
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.007 0.993 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.000 0.993 0.007
E61.2 Magnesium deficiency
0.000 0.993 0.006
S05.8 Other injuries of eye and orbit
0.000 0.993 0.006
E16 Other disorders of pancreatic internal secretion
0.000 0.993 0.006
S06.01 Concussion (with open intracranial wound)
0.000 0.994 0.006
H21.2 Degeneration of iris and ciliary body
0.000 0.994 0.006
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.994 0.006
Q61.0 Congenital single renal cyst
0.006 0.994 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.000 0.994 0.006
E53.8 Deficiency of other specified B group vitamins
0.000 0.994 0.006
Q61.4 Renal dysplasia
0.006 0.994 0.000
S83.7 Injury to multiple structures of knee
0.000 0.994 0.006
Z86.5 Personal history of other mental and behavioural disorders
0.006 0.994 0.000
H18 Other disorders of cornea
0.000 0.994 0.006
E23.0 Hypopituitarism
0.000 0.994 0.006
H16 Keratitis
0.000 0.994 0.006
Q61.8 Other cystic kidney diseases
0.006 0.994 0.000
Q61.1 Polycystic kidney, infantile type
0.006 0.994 0.000
H18.1 Bullous keratopathy
0.000 0.994 0.006
H54 Blindness and low vision
0.000 0.994 0.006
H21.3 Cyst of iris, ciliary body and anterior chamber
0.000 0.994 0.006
H54.7 Unspecified visual loss
0.000 0.994 0.006
E23.2 Diabetes insipidus
0.000 0.994 0.006
H21.9 Disorder of iris and ciliary body, unspecified
0.000 0.994 0.006
E67.8 Other specified hyperalimentation
0.000 0.994 0.006
E67.3 Hypervitaminosis D
0.000 0.994 0.006
E67.2 Megavitamin-B6 syndrome
0.000 0.994 0.006
E67.1 Hypercarotenaemia
0.000 0.994 0.006
E67.0 Hypervitaminosis A
0.000 0.994 0.006
H54.2 Low vision, both eyes
0.000 0.994 0.006
C18.2 Ascending colon
0.006 0.994 0.000
H54.6 Unqualified visual loss, one eye
0.000 0.994 0.006
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.000 0.994 0.005
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.000 0.994 0.006
M89.9 Disorder of bone, unspecified
0.000 0.994 0.005
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.994 0.005
K52.0 Gastro-enteritis and colitis due to radiation
0.000 0.994 0.005
E28.2 Polycystic ovarian syndrome
0.000 0.994 0.005
H16.1 Other superficial keratitis without conjunctivitis
0.000 0.995 0.005
H15 Disorders of sclera
0.000 0.995 0.005
G99.0 Autonomic neuropathy in endocrine and metabolic diseases
0.000 0.995 0.005
H21.4 Pupillary membranes
0.000 0.995 0.005
S01.0 Open wound of scalp
0.000 0.995 0.005
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.005 0.995 0.000
E21.4 Other specified disorders of parathyroid gland
0.000 0.995 0.005
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.000 0.995 0.005
H16.3 Interstitial and deep keratitis
0.000 0.995 0.005
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.995 0.005
E16.1 Other hypoglycaemia
0.000 0.995 0.005
I77.1 Stricture of artery
0.000 0.995 0.005
H16.8 Other keratitis
0.000 0.995 0.005
H16.4 Corneal neovascularisation
0.000 0.995 0.005
H22.1 Iridocyclitis in other diseases classified elsewhere
0.000 0.995 0.005
O14.2 HELLP syndrome
0.005 0.995 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.995 0.005
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.995 0.005
E16.4 Abnormal secretion of gastrin
0.000 0.995 0.005
E16.3 Increased secretion of glucagon
0.000 0.995 0.005
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.995 0.005
M06.9 Rheumatoid arthritis, unspecified
0.000 0.995 0.005
O14.1 Severe preeclampsia
0.005 0.995 0.000
H18.6 Keratoconus
0.000 0.995 0.005
K25.7 Chronic without haemorrhage or perforation
0.000 0.995 0.005
G99.8 Other specified disorders of nervous system in diseases classified elsewhere
0.000 0.995 0.005
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere
0.000 0.995 0.005
H18.0 Corneal pigmentations and deposits
0.000 0.995 0.005
H54.4 Blindness, one eye
0.000 0.995 0.005
H16.9 Keratitis, unspecified
0.000 0.995 0.005
M51.9 Intervertebral disk disorder, unspecified
0.004 0.995 0.000
H18.7 Other corneal deformities
0.000 0.995 0.005
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.995 0.005
H54.3 Unqualified visual loss, both eyes
0.000 0.995 0.005
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.000 0.995 0.005
E27 Other disorders of adrenal gland
0.000 0.995 0.005
H16.2 Keratoconjunctivitis
0.000 0.995 0.004
H15.1 Episcleritis
0.000 0.995 0.004
S09.9 Unspecified injury of head
0.000 0.995 0.005
E21.3 Hyperparathyroidism, unspecified
0.000 0.995 0.005
H18.2 Other corneal oedema
0.000 0.995 0.004
S05.1 Contusion of eyeball and orbital tissues
0.000 0.995 0.004
E04.9 Non-toxic goitre, unspecified
0.000 0.996 0.004
N60.8 Other benign mammary dysplasias
0.000 0.996 0.004
M89.8 Other specified disorders of bone
0.000 0.996 0.004
H20 Iridocyclitis
0.001 0.996 0.004
Z57 Occupational exposure to risk-factors
0.000 0.996 0.004
X62.8 Other specified place
0.004 0.996 0.000
Q60-Q64 Congenital malformations of the urinary system
0.004 0.996 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.996 0.004
E04.1 Non-toxic single thyroid nodule
0.000 0.996 0.004
H54.1 Blindness, one eye, low vision, other eye
0.000 0.996 0.004
M89.98 Disorder of bone, unspecified (Other)
0.000 0.996 0.004
H22.8 Other disorders of iris and ciliary body in diseases classified elsewhere
0.000 0.996 0.004
H22.0 Iridocyclitis in infectious and parasitic diseases classified elsewhere
0.000 0.996 0.004
M89.99 Disorder of bone, unspecified (Site unspecified)
0.000 0.996 0.004
M89.93 Disorder of bone, unspecified (Forearm)
0.000 0.996 0.004
H19.2 Keratitis and keratoconjunctivitis in other infectious and parasitic diseases classified elsewhere
0.000 0.996 0.004
S06.20 Diffuse brain injury (without open intracranial wound)
0.000 0.996 0.004
M89.91 Disorder of bone, unspecified (Shoulder region)
0.000 0.996 0.004
H15.8 Other disorders of sclera
0.000 0.996 0.004
I82.9 Embolism and thrombosis of unspecified vein
0.000 0.996 0.004
H17 Corneal scars and opacities
0.000 0.996 0.004
E21.2 Other hyperparathyroidism
0.000 0.996 0.004
H15.9 Disorder of sclera, unspecified
0.000 0.996 0.004

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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