TreeWAS – Variant ID: rs28498059

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E78.0 Pure hypercholesterolaemia	0.000	0.000	1.000
K90.0 Coeliac disease	0.000	0.000	1.000
L40.9 Psoriasis, unspecified	0.000	0.000	1.000
E10 Insulin-dependent diabetes mellitus	0.000	0.000	1.000
G35 Multiple sclerosis	1.000	0.000	0.000
I25 Chronic ischaemic heart disease	0.000	0.000	1.000
E10-E14 Diabetes mellitus	0.000	0.000	1.000
E10.9 Without complications	0.000	0.000	1.000
E83.1 Disorders of iron metabolism	1.000	0.000	0.000
I20-I25 Ischaemic heart diseases	0.000	0.000	1.000
L40 Psoriasis	0.000	0.000	1.000
E11 Non-insulin-dependent diabetes mellitus	0.000	0.000	1.000
M06.9 Rheumatoid arthritis, unspecified	0.000	0.000	1.000
E11.9 Without complications	0.000	0.000	1.000
I25.2 Old myocardial infarction	0.000	0.001	0.999
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.001	0.999
I25.1 Atherosclerotic heart disease	0.000	0.002	0.998
I25.8 Other forms of chronic ischaemic heart disease	0.000	0.003	0.997
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.003	0.997
L40.5 Arthropathic psoriasis	0.000	0.004	0.996
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.013	0.987
I21 Acute myocardial infarction	0.000	0.018	0.982
L40-L45 Papulosquamous disorders	0.000	0.020	0.980
E10.3 With ophthalmic complications	0.000	0.022	0.978
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.022	0.978
E14 Unspecified diabetes mellitus	0.000	0.024	0.976
E70-E90 Metabolic disorders	0.000	0.026	0.973
I22 Subsequent myocardial infarction	0.000	0.027	0.973
I25.5 Ischaemic cardiomyopathy	0.000	0.027	0.973
I10 Essential (primary) hypertension	0.000	0.028	0.972
I10-I15 Hypertensive diseases	0.000	0.030	0.970
E14.9 Without complications	0.000	0.041	0.959
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.041	0.959
L43 Lichen planus	0.000	0.043	0.957
I22.1 Subsequent myocardial infarction of inferior wall	0.000	0.046	0.954
Chapter IX Diseases of the circulatory system	0.000	0.054	0.946
I21.9 Acute myocardial infarction, unspecified	0.000	0.057	0.943
J45.9 Asthma, unspecified	0.000	0.057	0.943
L43.9 Lichen planus, unspecified	0.000	0.062	0.938
M06 Other rheumatoid arthritis	0.000	0.066	0.934
I24 Other acute ischaemic heart diseases	0.000	0.066	0.934
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.000	0.067	0.933
I12 Hypertensive renal disease	0.000	0.068	0.932
I21.4 Acute subendocardial myocardial infarction	0.000	0.076	0.924
E78.2 Mixed hyperlipidaemia	0.000	0.088	0.912
G35-G37 Demyelinating diseases of the central nervous system	0.909	0.091	0.000
E78.8 Other disorders of lipoprotein metabolism	0.000	0.103	0.897
E11.0 With coma	0.000	0.103	0.897
I20 Angina pectoris	0.000	0.104	0.896
I12.9 Hypertensive renal disease without renal failure	0.000	0.108	0.892
K90 Intestinal malabsorption	0.000	0.114	0.886
G37 Other demyelinating diseases of central nervous system	0.883	0.117	0.000
K51.9 Ulcerative colitis, unspecified	0.882	0.118	0.000
K51 Ulcerative colitis	0.881	0.119	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.121	0.879
E10.1 With ketoacidosis	0.000	0.134	0.866
I20.9 Angina pectoris, unspecified	0.000	0.138	0.862
M45.X9 Ankylosing spondylitis (Site unspecified)	0.000	0.140	0.860
E13 Other specified diabetes mellitus	0.000	0.140	0.860
M05-M14 Inflammatory polyarthropathies	0.000	0.141	0.859
M45 Ankylosing spondylitis	0.000	0.146	0.854
G37.9 Demyelinating disease of central nervous system, unspecified	0.849	0.151	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.151	0.849
L40.8 Other psoriasis	0.000	0.153	0.847
E11.1 With ketoacidosis	0.000	0.158	0.842
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.158	0.842
E10.4 With neurological complications	0.000	0.162	0.838
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.000	0.162	0.838
M45-M49 Spondylopathies	0.000	0.163	0.837
E78.5 Hyperlipidaemia, unspecified	0.000	0.167	0.833
# Top node	0.000	0.171	0.829
M70-M79 Other soft tissue disorders	0.000	0.175	0.825
L40.0 Psoriasis vulgaris	0.000	0.178	0.822
K51.3 Ulcerative (chronic) rectosigmoiditis	0.821	0.179	0.000
E74 Other disorders of carbohydrate metabolism	0.000	0.179	0.821
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.180	0.820
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.181	0.819
K51.8 Other ulcerative colitis	0.811	0.189	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.000	0.193	0.807
Chapter XII Diseases of the skin and subcutaneous tissue	0.000	0.195	0.805
I25.9 Chronic ischaemic heart disease, unspecified	0.000	0.196	0.804
E10.0 With coma	0.000	0.201	0.799
E10.8 With unspecified complications	0.000	0.203	0.797
M75 Shoulder lesions	0.000	0.204	0.796
M79 Other soft tissue disorders, not elsewhere classified	0.000	0.206	0.794
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.000	0.210	0.790
K51.4 Pseudopolyposis of colon	0.788	0.212	0.000
M75.0 Adhesive capsulitis of shoulder	0.000	0.213	0.787
I15 Secondary hypertension	0.000	0.217	0.782
I25.0 Atherosclerotic cardiovascular disease, so described	0.000	0.217	0.782
K90-K93 Other diseases of the digestive system	0.000	0.218	0.782
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.000	0.221	0.779
K58.0 Irritable bowel syndrome with diarrhoea	0.000	0.222	0.778
E10.6 With other specified complications	0.000	0.226	0.774
Chapter XI Diseases of the digestive system	0.000	0.226	0.774
M79.6 Pain in limb	0.000	0.228	0.772
E11.2 With renal complications	0.000	0.229	0.771
K55-K64 Other diseases of intestines	0.000	0.229	0.771
K57 Diverticular disease of intestine	0.000	0.229	0.771
K58 Irritable bowel syndrome	0.000	0.231	0.769
K51.5 Mucosal proctocolitis	0.769	0.231	0.000
E78.4 Other hyperlipidaemia	0.000	0.235	0.765
M06.3 Rheumatoid nodule	0.000	0.236	0.764
E10.5 With peripheral circulatory complications	0.000	0.237	0.763
K51.2 Ulcerative (chronic) proctitis	0.762	0.238	0.000
K57.3 Diverticular disease of large intestine without perforation or abscess	0.000	0.240	0.760
E13.9 Without complications	0.000	0.241	0.759
I12.0 Hypertensive renal disease with renal failure	0.000	0.242	0.758
I25.3 Aneurysm of heart	0.000	0.242	0.758
M79.65 Pain in limb (Pelvic region and thigh)	0.000	0.244	0.756
M06.4 Inflammatory polyarthropathy	0.000	0.244	0.756
E11.6 With other specified complications	0.000	0.246	0.754
I21.0 Acute transmural myocardial infarction of anterior wall	0.000	0.251	0.749
M07 Psoriatic and enteropathic arthropathies	0.000	0.251	0.749
E78.1 Pure hyperglyceridaemia	0.000	0.253	0.747
M79.7 Fibromyalgia	0.000	0.256	0.744
E14.3 With ophthalmic complications	0.000	0.259	0.741
I24.8 Other forms of acute ischaemic heart disease	0.000	0.264	0.736
E10.2 With renal complications	0.000	0.266	0.734
Chapter VIII Diseases of the ear and mastoid process	0.000	0.267	0.733
M79.1 Myalgia	0.000	0.268	0.732
M70 Soft tissue disorders related to use, overuse and pressure	0.000	0.273	0.727
E11.5 With peripheral circulatory complications	0.000	0.274	0.726
G37.8 Other specified demyelinating diseases of central nervous system	0.724	0.276	0.000
M75.4 Impingement syndrome of shoulder	0.000	0.279	0.721
L42 Pityriasis rosea	0.000	0.279	0.720
M79.79 Fibromyalgia (Site unspecified)	0.000	0.280	0.720
E10.7 With multiple complications	0.000	0.283	0.717
I25.6 Silent myocardial ischaemia	0.000	0.283	0.717
E12 Malnutrition-related diabetes mellitus	0.000	0.283	0.717
I23 Certain current complications following acute myocardial infarction	0.000	0.283	0.717
L40.4 Guttate psoriasis	0.000	0.283	0.717
L40.2 Acrodermatitis continua	0.000	0.283	0.717
L40.1 Generalised pustular psoriasis	0.000	0.283	0.717
E11.7 With multiple complications	0.000	0.283	0.717
E78.6 Lipoprotein deficiency	0.000	0.285	0.715
E78.3 Hyperchylomicronaemia	0.000	0.285	0.715
I22.8 Subsequent myocardial infarction of other sites	0.000	0.286	0.714
M06.98 Rheumatoid arthritis, unspecified (Other)	0.000	0.287	0.713
L43.8 Other lichen planus	0.000	0.287	0.713
E74.3 Other disorders of intestinal carbohydrate absorption	0.000	0.288	0.712
E16 Other disorders of pancreatic internal secretion	0.000	0.293	0.707
I22.0 Subsequent myocardial infarction of anterior wall	0.000	0.294	0.706
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.294	0.706
H60-H62 Diseases of external ear	0.000	0.295	0.705
I21.X Presumed acute myicardial infaction (unconfirmed)	0.000	0.296	0.704
L44 Other papulosquamous disorders	0.000	0.297	0.703
L41 Parapsoriasis	0.000	0.297	0.703
L45 Papulosquamous disorders in diseases classified elsewhere	0.000	0.297	0.703
I11 Hypertensive heart disease	0.000	0.299	0.701
E14.8 With unspecified complications	0.000	0.300	0.700
E14.7 With multiple complications	0.000	0.300	0.700
E14.6 With other specified complications	0.000	0.300	0.700
E14.5 With peripheral circulatory complications	0.000	0.300	0.700
E14.2 Withrenal complications	0.000	0.300	0.700
E14.1 With ketoacidosis	0.000	0.300	0.700
E14.0 With coma	0.000	0.300	0.700
K57.8 Diverticular disease of intestine, part unspecified, with perforation and abscess	0.000	0.302	0.698
E79 Disorders of purine and pyrimidine metabolism	0.000	0.302	0.698
E77 Disorders of glycoprotein metabolism	0.000	0.302	0.698
E76 Disorders of glycosaminoglycan metabolism	0.000	0.302	0.698
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.302	0.698
E72 Other disorders of amino-acid metabolism	0.000	0.302	0.698
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.302	0.698
E70 Disorders of aromatic amino-acid metabolism	0.000	0.302	0.698
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.302	0.698
K60 Fissure and fistula of anal and rectal regions	0.000	0.304	0.696
I13 Hypertensive heart and renal disease	0.000	0.305	0.695
K57.1 Diverticular disease of small intestine without perforation or abscess	0.000	0.310	0.690
M05 Seropositive rheumatoid arthritis	0.000	0.312	0.688
H60 Otitis externa	0.000	0.313	0.687
L43.3 Subacute (active) lichen planus	0.000	0.314	0.686
L43.2 Lichenoid drug reaction	0.000	0.314	0.686
L43.1 Bullous lichen planus	0.000	0.314	0.686
L43.0 Hypertrophic lichen planus	0.000	0.314	0.686
M07.3 Other psoriatic arthropathies	0.000	0.316	0.684
M79.18 Myalgia (Other)	0.000	0.322	0.678
I22.9 Subsequent myocardial infarction of unspecified site	0.000	0.323	0.677
K51.1 Ulcerative (chronic) ileocolitis	0.677	0.323	0.000
E84 Cystic fibrosis	0.000	0.326	0.674
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.000	0.327	0.673
M49 Spondylopathies in diseases classified elsewhere	0.000	0.328	0.672
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.328	0.672
I20.0 Unstable angina	0.000	0.329	0.671
M06.8 Other specified rheumatoid arthritis	0.000	0.330	0.670
M06.2 Rheumatoid bursitis	0.000	0.330	0.670
M06.1 Adult-onset Still's disease	0.000	0.330	0.670
M79.62 Pain in limb (Upper arm)	0.000	0.331	0.669
H65-H75 Diseases of middle ear and mastoid	0.000	0.335	0.665
K60.2 Anal fissure, unspecified	0.000	0.337	0.663
K90.8 Other intestinal malabsorption	0.000	0.339	0.661
K90.9 Intestinal malabsorption, unspecified	0.000	0.342	0.658
K51.0 Ulcerative (chronic) enterocolitis	0.658	0.342	0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.653	0.346	0.000
G36 Other acute disseminated demyelination	0.652	0.348	0.000
H60.9 Otitis externa, unspecified	0.000	0.351	0.649
M70.4 Prepatellar bursitis	0.000	0.351	0.649
I15.1 Hypertension secondary to other renal disorders	0.000	0.352	0.648
E14.4 With neurological complications	0.000	0.354	0.646
M06.34 Rheumatoid nodule (Hand)	0.000	0.355	0.645
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.355	0.645
E40-E46 Malnutrition	0.000	0.355	0.645
K57.9 Diverticular disease of intestine, part unspecified, without perforation or abscess	0.000	0.356	0.644
M75.2 Bicipital tendinitis	0.000	0.357	0.643
K60.0 Acute anal fissure	0.000	0.358	0.642
E11.4 With neurological complications	0.000	0.359	0.641
M79.64 Pain in limb (Hand)	0.000	0.360	0.640
E85 Amyloidosis	0.000	0.362	0.638
K90.3 Pancreatic steatorrhoea	0.000	0.365	0.635
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.365	0.635
K90.1 Tropical sprue	0.000	0.365	0.635
G37.5 Concentric sclerosis [Balo]	0.633	0.367	0.000
G37.4 Subacute necrotising myelitis	0.633	0.367	0.000
G37.2 Central pontine myelinolysis	0.633	0.367	0.000
G37.1 Central demyelination of corpus callosum	0.633	0.367	0.000
G37.0 Diffuse sclerosis	0.633	0.367	0.000
L40.3 Pustulosis palmaris et plantaris	0.000	0.368	0.632
I24.1 Dressler's syndrome	0.000	0.377	0.623
I00-I02 Acute rheumatic fever	0.000	0.381	0.619
M46 Other inflammatory spondylopathies	0.000	0.381	0.619
M79.60 Pain in limb (Multiple sites)	0.000	0.381	0.618
I21.3 Acute transmural myocardial infarction of unspecified site	0.000	0.383	0.617
E13.8 With unspecified complications	0.000	0.383	0.616
E13.7 With multiple complications	0.000	0.383	0.616
E13.6 With other specified complications	0.000	0.383	0.616
E13.5 With peripheral circulatory complications	0.000	0.383	0.616
E13.4 With neurological complications	0.000	0.383	0.616
E13.3 With ophthalmic complications	0.000	0.383	0.616
E13.2 With renal complications	0.000	0.383	0.616
E13.1 With ketoacidosis	0.000	0.383	0.616
E13.0 With coma	0.000	0.383	0.616
M09 Juvenile arthritis in diseases classified elsewhere	0.000	0.384	0.616
M08 Juvenile arthritis	0.000	0.384	0.616
H71 Cholesteatoma of middle ear	0.000	0.386	0.614
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.000	0.388	0.612
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.000	0.388	0.612
M45.X6 Ankylosing spondylitis (Lumbar region)	0.000	0.388	0.612
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.000	0.388	0.612
M45.X4 Ankylosing spondylitis (Thoracic region)	0.000	0.388	0.612
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.000	0.388	0.612
M45.X2 Ankylosing spondylitis (Cervical region)	0.000	0.388	0.612
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.000	0.388	0.612
H74 Other disorders of middle ear and mastoid	0.000	0.389	0.611
I25.4 Coronary artery aneurysm	0.000	0.389	0.611
E83 Disorders of mineral metabolism	0.279	0.389	0.332
E89.3 Postprocedural hypopituitarism	0.000	0.390	0.610
E16.2 Hypoglycaemia, unspecified	0.000	0.392	0.608
M70.6 Trochanteric bursitis	0.000	0.394	0.606
E20-E35 Disorders of other endocrine glands	0.000	0.397	0.603
K70-K77 Diseases of liver	0.000	0.397	0.603
M11 Other crystal arthropathies	0.000	0.398	0.602
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.000	0.399	0.601
M05.9 Seropositive rheumatoid arthritis, unspecified	0.000	0.403	0.597
I20.1 Angina pectoris with documented spasm	0.000	0.405	0.595
Chapter XVI Certain conditions originating in the perinatal period	0.000	0.405	0.595
M70.46 Prepatellar bursitis-Lower Leg	0.000	0.407	0.593
M73 Soft tissue disorders in diseases classified elsewhere	0.000	0.408	0.592
K57.5 Diverticular disease of both small and large intestine without perforation or abscess	0.000	0.409	0.591
E74.9 Disorder of carbohydrate metabolism, unspecified	0.000	0.411	0.589
E74.8 Other specified disorders of carbohydrate metabolism	0.000	0.411	0.589
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.000	0.411	0.589
E74.2 Disorders of galactose metabolism	0.000	0.411	0.589
E74.1 Disorders of fructose metabolism	0.000	0.411	0.589
E74.0 Glycogen storage disease	0.000	0.411	0.589
E15 Nondiabetic hypoglycaemic coma	0.000	0.412	0.588
M79.67 Pain in limb (Ankle and foot)	0.000	0.416	0.584
H60.3 Other infective otitis externa	0.000	0.418	0.582
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.000	0.420	0.580
M07.39 Other psoriatic arthropathies (Site unspecified)	0.000	0.421	0.579
M75.8 Other shoulder lesions	0.000	0.429	0.571
M79.3 Panniculitis, unspecified	0.000	0.431	0.569
M79.15 Myalgia (Pelvic region and thigh)	0.000	0.431	0.569
M77 Other enthesopathies	0.000	0.432	0.567
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.000	0.438	0.561
I15.9 Seconday hypertension, unspecified	0.000	0.439	0.561
I15.8 Other secondary hypertension	0.000	0.439	0.561
I15.2 Hypertension secondary to endocrine disorders	0.000	0.439	0.561
I15.0 Renovascular hypertension	0.000	0.439	0.561
K93 Disorders of other digestive organs in diseases classified elsewhere	0.000	0.439	0.561
H74.8 Other specified disorders of middle ear and mastoid	0.000	0.439	0.561
K59 Other functional intestinal disorders	0.000	0.441	0.559
M79.9 Soft tissue disorder, unspecified	0.000	0.442	0.558
M07.30 Other psoriatic arthropathies (Multiple sites)	0.000	0.442	0.558
E11.8 With unspecified complications	0.000	0.444	0.556
M79.63 Pain in limb (Forearm)	0.000	0.445	0.555
H73 Other disorders of tympanic membrane	0.000	0.445	0.555
M79.4 Hypertrophy of (infrapatellar) fat pad	0.000	0.446	0.554
M49.5 Collapsed vertebra in diseases classified elsewhere	0.000	0.447	0.553
K64 Haemorrhoids and perianal venous thrombosis	0.000	0.447	0.553
K57.4 Diverticular disease of both small and large intestine with perforation and abscess	0.000	0.447	0.553
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.448	0.552
M14 Arthropathies in other diseases classified elsewhere	0.000	0.448	0.552
M91-M94 Chondropathies	0.000	0.449	0.551
M07.36 Other psoriatic arthropathies (Lower leg)	0.000	0.449	0.551
M06.0 Seronegative rheumatoid arthritis	0.000	0.450	0.550
H60.1 Cellulitis of external ear	0.000	0.451	0.549
M06.39 Rheumatoid nodule (Site unspecified)	0.000	0.452	0.548
M06.38 Rheumatoid nodule (Other)	0.000	0.452	0.548
M06.36 Rheumatoid nodule (Lower leg)	0.000	0.452	0.548
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.000	0.452	0.548
M06.33 Rheumatoid nodule (Forearm)	0.000	0.452	0.548
M06.32 Rheumatoid nodule (Upper arm)	0.000	0.452	0.548
M06.31 Rheumatoid nodule (Shoulder region)	0.000	0.452	0.548
M06.30 Rheumatoid nodule (Multiple sites)	0.000	0.452	0.548
M79.11 Myalgia (Shoulder region)	0.000	0.455	0.545
E73 Lactose intolerance	0.001	0.457	0.543
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.457	0.543
M06.37 Rheumatoid nodule (Ankle and foot)	0.000	0.457	0.542
M06.48 Inflammatory polyarthropathy (Other)	0.000	0.458	0.542
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.000	0.458	0.542
M06.46 Inflammatory polyarthropathy (Lower leg)	0.000	0.458	0.542
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.000	0.458	0.542
M06.44 Inflammatory polyarthropathy (Hand)	0.000	0.458	0.542
M06.43 Inflammatory polyarthropathy (Forearm)	0.000	0.458	0.542
M06.42 Inflammatory polyarthropathy (Upper arm)	0.000	0.458	0.542
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.000	0.458	0.542
M12 Other specific arthropathies	0.000	0.461	0.539
H60.8 Other otitis externa	0.000	0.462	0.538
M79.16 Myalgia (Lower leg)	0.000	0.463	0.537
M07.5 Arthropathy in ulcerative colitis	0.000	0.463	0.537
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.000	0.463	0.537
M07.2 Psoriatic spondylitis	0.000	0.463	0.537
M07.1 Arthritis mutilans	0.000	0.463	0.537
M07.0 Distal interphalangeal psoriatic arthropathy	0.000	0.463	0.537
M46.4 Discitis, unspecified	0.000	0.465	0.535
K74 Fibrosis and cirrhosis of liver	0.000	0.465	0.535
E80 Disorders of porphyrin and bilirubin metabolism	0.000	0.466	0.534
M79.78 Fibromyalgia (Other)	0.000	0.466	0.534
M79.77 Fibromyalgia (Ankle and foot)	0.000	0.466	0.534
M79.76 Fibromyalgia (Lower leg)	0.000	0.466	0.534
M79.75 Fibromyalgia (Pelvic region and thigh)	0.000	0.466	0.534
M79.74 Fibromyalgia (Hand)	0.000	0.466	0.534
M79.73 Fibromyalgia (Forearm)	0.000	0.466	0.534
M79.72 Fibromyalgia (Upper arm)	0.000	0.466	0.534
M79.71 Fibromyalgia (Shoulder region)	0.000	0.466	0.534
E28 Ovarian dysfunction	0.000	0.472	0.528
M79.17 Myalgia (Ankle and foot)	0.000	0.475	0.525
M79.14 Myalgia (Hand)	0.000	0.475	0.525
M79.13 Myalgia (Forearm)	0.000	0.475	0.525
M79.12 Myalgia (Upper arm)	0.000	0.475	0.525
K72 Hepatic failure, not elsewhere classified	0.000	0.475	0.525
M79.61 Pain in limb (Shoulder region)	0.000	0.476	0.524
M79.19 Myalgia (Site unspecified)	0.000	0.476	0.524
K57.0 Diverticular disease of small intestine with perforation and abscess	0.000	0.478	0.522
M70.9 Unspecified soft tissue disorder related to use, overuse and pressure	0.000	0.479	0.521
M70.8 Other soft tissue disorders related to use, overuse and pressure	0.000	0.479	0.521
M70.5 Other bursitis of knee	0.000	0.479	0.521
M70.1 Bursitis of hand	0.000	0.479	0.521
M70.0 Chronic crepitant synovitis of hand and wrist	0.000	0.479	0.521
M70.65 Trochanteric bursitis-Pelvic/Thigh	0.000	0.481	0.519
H66 Suppurative and unspecified otitis media	0.000	0.482	0.517
K60.5 Anorectal fistula	0.000	0.485	0.515
E88 Other metabolic disorders	0.000	0.486	0.514
H61 Other disorders of external ear	0.000	0.486	0.514
E12.9 Without complications	0.000	0.486	0.514
E12.8 With unspecified complications	0.000	0.486	0.514
E12.7 With multiple complications	0.000	0.486	0.514
E12.6 With other specified complications	0.000	0.486	0.514
E12.5 With peripheral circulatory complications	0.000	0.486	0.514
E12.4 With neurological complications	0.000	0.486	0.514
E12.3 With ophthalmic complications	0.000	0.486	0.514
E12.2 With renal complications	0.000	0.486	0.514
E12.1 With ketoacidosis	0.000	0.486	0.514
E12.0 With coma	0.000	0.486	0.514
I23.8 Other current complications following acute myocardial infarction	0.000	0.486	0.514
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.000	0.486	0.514
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.000	0.486	0.514
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.000	0.486	0.514
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.000	0.486	0.514
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.000	0.486	0.514
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.000	0.486	0.514
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.000	0.486	0.514
H60.5 Acute otitis externa, non-infective	0.000	0.491	0.509
I11.0 Hypertensive heart disease with (congestive) heart failure	0.000	0.492	0.508
M79.69 Pain in limb (Site unspecified)	0.000	0.492	0.508
K74.3 Primary biliary cirrhosis	0.000	0.493	0.507
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.493	0.507
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.493	0.507
E16.4 Abnormal secretion of gastrin	0.000	0.493	0.507
E16.3 Increased secretion of glucagon	0.000	0.493	0.507
E16.1 Other hypoglycaemia	0.000	0.493	0.507
H74.4 Polyp of middle ear	0.000	0.494	0.506
L41.9 Parapsoriasis, unspecified	0.000	0.496	0.504
L41.8 Other parapsoriasis	0.000	0.496	0.504
L41.5 Retiform parapsoriasis	0.000	0.496	0.504
L41.4 Large plaque parapsoriasis	0.000	0.496	0.504
L41.3 Small plaque parapsoriasis	0.000	0.496	0.504
L41.2 Lymphomatoid papulosis	0.000	0.496	0.504
L41.1 Pityriasis lichenoides chronica	0.000	0.496	0.504
L41.0 Pityriasis lichenoides et varioliformis acuta	0.000	0.496	0.504
L44.9 Papulosquamous disorder, unspecified	0.000	0.496	0.504
L44.8 Other specified papulosquamous disorders	0.000	0.496	0.504
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]	0.000	0.496	0.504
L44.3 Lichen ruber moniliformis	0.000	0.496	0.504
L44.2 Lichen striatus	0.000	0.496	0.504
L44.1 Lichen nitidus	0.000	0.496	0.504
L44.0 Pityriasis rubra pilaris	0.000	0.496	0.504
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.497	0.503
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.000	0.499	0.500
E70.8 Other disorders of aromatic amino-acid metabolism	0.000	0.499	0.500
E70.3 Albinism	0.000	0.499	0.500
E70.2 Disorders of tyrosine metabolism	0.000	0.499	0.500
E70.1 Other hyperphenylalaninaemias	0.000	0.499	0.500
E70.0 Classical phenylketonuria	0.000	0.499	0.500
E71.3 Disorders of fatty-acid metabolism	0.000	0.499	0.500
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.000	0.499	0.500
E71.1 Other disorders of branched-chain amino-acid metabolism	0.000	0.499	0.500
E71.0 Maple-syrup-urine disease	0.000	0.499	0.500
E72.9 Disorder of amino-acid metabolism, unspecified	0.000	0.499	0.500
E72.8 Other specified disorders of amino-acid metabolism	0.000	0.499	0.500
E72.5 Disorders of glycine metabolism	0.000	0.499	0.500
E72.4 Disorders of ornithine metabolism	0.000	0.499	0.500
E72.3 Disorders of lysine and hydroxylysine metabolism	0.000	0.499	0.500
E72.2 Disorders of urea cycle metabolism	0.000	0.499	0.500
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.000	0.499	0.500
E72.0 Disorders of amino-acid transport	0.000	0.499	0.500
E75.6 Lipid storage disorder, unspecified	0.000	0.499	0.500
E75.5 Other lipid storage disorders	0.000	0.499	0.500
E75.4 Neuronal ceroid lipofuscinosis	0.000	0.499	0.500
E75.3 Sphingolipidosis, unspecified	0.000	0.499	0.500
E75.2 Other sphingolipidosis	0.000	0.499	0.500
E75.1 Other gangliosidosis	0.000	0.499	0.500
E75.0 GM2 gangliosidosis	0.000	0.499	0.500
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.000	0.499	0.500
E76.8 Other disorders of glucosaminoglycan metabolism	0.000	0.499	0.500
E76.3 Mucopolysaccharidosis, unspecified	0.000	0.499	0.500
E76.2 Other mucopolysaccharidoses	0.000	0.499	0.500
E76.1 Mucopolysaccharidosis, type II	0.000	0.499	0.500
E76.0 Mucopolysaccharidosis, type I	0.000	0.499	0.500
E77.9 Disorder of glycoprotein metabolism, unspecified	0.000	0.499	0.500
E77.8 Other disorders of glycoprotein metabolism	0.000	0.499	0.500
E77.1 Defects in glycoprotein degradation	0.000	0.499	0.500
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.000	0.499	0.500
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.000	0.499	0.500
E79.8 Other disorders of purine and pyrimidine metabolism	0.000	0.499	0.500
E79.1 Lesch-Nyhan syndrome	0.000	0.499	0.500
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.000	0.499	0.500
H60.4 Cholesteatoma of external ear	0.000	0.501	0.499
H74.9 Disorder of middle ear and mastoid, unspecified	0.000	0.501	0.499
I13.9 Hypertensive heart and renal disease, unspecified	0.000	0.501	0.499
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.000	0.501	0.499
I13.1 Hypertensive heart and renal disease with renal failure	0.000	0.501	0.499
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.000	0.501	0.499
L10-L14 Bullous disorders	0.000	0.502	0.498
K73 Chronic hepatitis, not elsewhere classified	0.000	0.503	0.497
M75.3 Calcific tendinitis of shoulder	0.000	0.504	0.496
K75 Other inflammatory liver diseases	0.000	0.504	0.496
E28.2 Polycystic ovarian syndrome	0.000	0.505	0.495
M70.7 Other bursitis of hip	0.000	0.505	0.495
M05.8 Other seropositive rheumatoid arthritis	0.000	0.507	0.493
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.000	0.507	0.493
M05.1 Rheumatoid lung disease	0.000	0.507	0.493
M05.0 Felty's syndrome	0.000	0.507	0.493
M07.6 Other enteropathic arthropathies	0.000	0.507	0.493
H60.2 Malignant otitis externa	0.000	0.507	0.493
M79.68 Pain in limb (Other)	0.000	0.507	0.492
E23 Hypofunction and other disorders of pituitary gland	0.000	0.508	0.492
M07.38 Other psoriatic arthropathies (Other)	0.000	0.510	0.490
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.000	0.510	0.490
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.000	0.510	0.490
M07.34 Other psoriatic arthropathies (Hand)	0.000	0.510	0.490
M07.33 Other psoriatic arthropathies (Forearm)	0.000	0.510	0.490
M07.32 Other psoriatic arthropathies (Upper arm)	0.000	0.510	0.490
M07.31 Other psoriatic arthropathies (Shoulder region)	0.000	0.510	0.490
K59.9 Functional intestinal disorder, unspecified	0.000	0.511	0.489
H66.3 Other chronic suppurative otitis media	0.000	0.511	0.489
M70.2 Olecranon bursitis	0.000	0.512	0.488
M70.3 Other bursitis of elbow	0.000	0.512	0.487
M77.1 Lateral epicondylitis	0.000	0.513	0.487
M65-M68 Disorders of synovium and tendon	0.000	0.515	0.485
E84.8 Cystic fibrosis with other manifestations	0.000	0.517	0.483
E84.1 Cystic fibrosis with intestinal manifestations	0.000	0.517	0.483
E84.0 Cystic fibrosis with pulmonary manifestations	0.000	0.517	0.483
M79.5 Residual foreign body in soft tissue	0.000	0.518	0.482
E78.9 Disorder of lipoprotein metabolism, unspecified	0.000	0.518	0.482
M49.8 Spondylopathy in other diseases classified elsewhere	0.000	0.518	0.482
M49.4 Neuropathic spondylopathy	0.000	0.518	0.482
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere	0.000	0.518	0.482
M49.2 Enterobacterial spondylitis	0.000	0.518	0.482
M49.1 Brucella spondylitis	0.000	0.518	0.482
M49.0 Tuberculosis of spine	0.000	0.518	0.482
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.000	0.518	0.482
E89.8 Other postprocedural endocrine and metabolic disorders	0.000	0.518	0.482
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.000	0.518	0.482
E89.5 Postprocedural testicular hypofunction	0.000	0.518	0.482
E89.1 Postprocedural hypoinsulinaemia	0.000	0.518	0.482
M06.19 Adult-onset Still's disease (Site unspecified)	0.000	0.520	0.480
M06.18 Adult-onset Still's disease (Other)	0.000	0.520	0.480
M06.17 Adult-onset Still's disease (Ankle and foot)	0.000	0.520	0.480
M06.16 Adult-onset Still's disease (Lower leg)	0.000	0.520	0.480
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.000	0.520	0.480
M06.14 Adult-onset Still's disease (Hand)	0.000	0.520	0.480
M06.13 Adult-onset Still's disease (Forearm)	0.000	0.520	0.480
M06.12 Adult-onset Still's disease (Upper arm)	0.000	0.520	0.480
M06.11 Adult-onset Still's disease (Shoulder region)	0.000	0.520	0.480
M06.10 Adult-onset Still's disease (Multiple sites)	0.000	0.520	0.480
M06.29 Rheumatoid bursitis (Site unspecified)	0.000	0.520	0.480
M06.28 Rheumatoid bursitis (Other)	0.000	0.520	0.480
M06.27 Rheumatoid bursitis (Ankle and foot)	0.000	0.520	0.480
M06.26 Rheumatoid bursitis (Lower leg)	0.000	0.520	0.480

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations