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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs28548100
log Bayes Factor = 8.90333
Chromosome 10   position 47,096,896  (GRCh37) Explore rs28548100 on Ensembl!
Variant rs28548100 is part of Cluster X0264

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
M45-M49 Spondylopathies
0.999 0.001 0.000
M47 Spondylosis
0.999 0.001 0.000
I73 Other peripheral vascular diseases
0.998 0.002 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.997 0.003 0.000
M70-M79 Other soft tissue disorders
0.996 0.004 0.000
M47.8 Other spondylosis
0.996 0.004 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.992 0.008 0.000
I77 Other disorders of arteries and arterioles
0.988 0.012 0.000
I73.9 Peripheral vascular disease, unspecified
0.986 0.014 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.984 0.016 0.000
M47.9 Spondylosis, unspecified
0.981 0.019 0.000
M47.86 Other spondylosis (Lumbar region)
0.981 0.019 0.000
I77.1 Stricture of artery
0.980 0.020 0.000
Chapter VII Diseases of the eye and adnexa
0.979 0.021 0.000
E10-E14 Diabetes mellitus
0.975 0.025 0.000
M79.6 Pain in limb
0.975 0.025 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.967 0.033 0.000
M79.66 Pain in limb (Lower leg)
0.964 0.036 0.000
Chapter VI Diseases of the nervous system
0.962 0.038 0.000
I73.0 Raynaud's syndrome
0.960 0.040 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.959 0.041 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.956 0.044 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.952 0.048 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.952 0.048 0.000
E11 Non-insulin-dependent diabetes mellitus
0.950 0.050 0.000
H53-H54 Visual disturbances and blindness
0.949 0.051 0.000
H55-H59 Other disorders of eye and adnexa
0.948 0.052 0.000
M40-M43 Deforming dorsopathies
0.943 0.057 0.000
R42 Dizziness and giddiness
0.940 0.060 0.000
I95 Hypotension
0.936 0.064 0.000
M79.7 Fibromyalgia
0.935 0.065 0.000
H53 Visual disturbances
0.931 0.069 0.000
I30-I52 Other forms of heart disease
0.929 0.071 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.922 0.078 0.000
D50-D53 Nutritional anaemias
0.921 0.079 0.000
I95.1 Orthostatic hypotension
0.919 0.081 0.000
D50 Iron deficiency anaemia
0.911 0.089 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.909 0.091 0.000
M20-M25 Other joint disorders
0.904 0.096 0.000
S40-S49 Injuries to the shoulder and upper arm
0.902 0.098 0.000
H53.8 Other visual disturbances
0.901 0.099 0.000
I45 Other conduction disorders
0.901 0.099 0.000
G70-G73 Diseases of myoneural junction and muscle
0.899 0.101 0.000
I47 Paroxysmal tachycardia
0.898 0.102 0.000
M43 Other deforming dorsopathies
0.894 0.106 0.000
S50-S59 Injuries to the elbow and forearm
0.892 0.108 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.891 0.109 0.000
R45 Symptoms and signs involving emotional state
0.891 0.109 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.891 0.109 0.000
H55 Nystagmus and other irregular eye movements
0.887 0.113 0.000
M65-M68 Disorders of synovium and tendon
0.885 0.115 0.000
E20-E35 Disorders of other endocrine glands
0.882 0.118 0.000
M79.69 Pain in limb (Site unspecified)
0.880 0.120 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.878 0.122 0.000
I72 Other aneurysm
0.874 0.126 0.000
I74 Arterial embolism and thrombosis
0.871 0.129 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.868 0.132 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.866 0.134 0.000
M86-M90 Other osteopathies
0.865 0.135 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.865 0.135 0.000
S80-S89 Injuries to the knee and lower leg
0.865 0.135 0.000
D50.9 Iron deficiency anaemia, unspecified
0.864 0.136 0.000
M25 Other joint disorders, not elsewhere classified
0.862 0.138 0.000
E11.9 Without complications
0.861 0.139 0.000
M79.79 Fibromyalgia (Site unspecified)
0.861 0.139 0.000
E10 Insulin-dependent diabetes mellitus
0.857 0.143 0.000
S42 Fracture of shoulder and upper arm
0.857 0.143 0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract
0.846 0.154 0.000
M43.1 Spondylolisthesis
0.844 0.156 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.838 0.162 0.000
S10-S19 Injuries to the neck
0.837 0.163 0.000
I45.9 Conduction disorder, unspecified
0.833 0.167 0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.831 0.169 0.000
H53.2 Diplopia
0.829 0.171 0.000
T66-T78 Other and unspecified effects of external causes
0.828 0.172 0.000
S42.2 Fracture of upper end of humerus
0.826 0.174 0.000
M79.1 Myalgia
0.825 0.175 0.000
Chapter XX External causes of morbidity and mortality
0.824 0.176 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.823 0.177 0.000
I77.2 Rupture of artery
0.818 0.182 0.000
I47.1 Supraventricular tachycardia
0.818 0.182 0.000
S52 Fracture of forearm
0.813 0.187 0.000
E11.4 With neurological complications
0.812 0.188 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.811 0.189 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.811 0.189 0.000
E14 Unspecified diabetes mellitus
0.810 0.190 0.000
S70-S79 Injuries to the hip and thigh
0.810 0.190 0.000
M79.63 Pain in limb (Forearm)
0.808 0.192 0.000
R47-R49 Symptoms and signs involving speech and voice
0.807 0.193 0.000
H53.0 Amblyopia ex anopsia
0.806 0.194 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.806 0.194 0.000
G20-G26 Extrapyramidal and movement disorders
0.806 0.194 0.000
G70 Myasthenia gravis and other myoneural disorders
0.805 0.195 0.000
S42.20 Fracture of upper end of humerus (closed)
0.804 0.196 0.000
M25.7 Osteophyte
0.799 0.201 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.799 0.201 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.798 0.202 0.000
R45.8 Other symptoms and signs involving emotional state
0.795 0.205 0.000
H10-H13 Disorders of conjunctiva
0.794 0.206 0.000
M46 Other inflammatory spondylopathies
0.790 0.210 0.000
M79.70 Fibromyalgia (Multiple sites)
0.788 0.212 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.786 0.214 0.000
Chapter V Mental and behavioural disorders
0.786 0.214 0.000
S52.0 Fracture of upper end of ulna
0.786 0.214 0.000
I45.1 Other and unspecified right bundle-branch block
0.784 0.216 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.782 0.218 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.776 0.224 0.000
M79.2 Neuralgia and neuritis, unspecified
0.776 0.224 0.000
G40-G47 Episodic and paroxysmal disorders
0.776 0.224 0.000
S90-S99 Injuries to the ankle and foot
0.775 0.225 0.000
E11.3 With ophthalmic complications
0.775 0.225 0.000
E11.0 With coma
0.774 0.225 0.000
D50.8 Other iron deficiency anaemias
0.774 0.226 0.000
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum
0.773 0.227 0.000
G30-G32 Other degenerative diseases of the nervous system
0.773 0.227 0.000
H57 Other disorders of eye and adnexa
0.771 0.229 0.000
R45.1 Restlessness and agitation
0.770 0.230 0.000
E10.9 Without complications
0.769 0.231 0.000
H30-H36 Disorders of choroid and retina
0.769 0.231 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.768 0.232 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.768 0.232 0.000
E27 Other disorders of adrenal gland
0.767 0.233 0.000
S52.00 Fracture of upper end of ulna (closed)
0.766 0.234 0.000
M60-M63 Disorders of muscles
0.764 0.236 0.000
G25 Other extrapyramidal and movement disorders
0.763 0.237 0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.761 0.239 0.000
I47.2 Ventricular tachycardia
0.760 0.240 0.000
M24 Other specific joint derangements
0.758 0.242 0.000
M20 Acquired deformities of fingers and toes
0.754 0.246 0.000
M77 Other enthesopathies
0.754 0.246 0.000
M49 Spondylopathies in diseases classified elsewhere
0.754 0.246 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.753 0.246 0.000
T18 Foreign body in alimentary tract
0.753 0.247 0.000
T17 Foreign body in respiratory tract
0.751 0.249 0.000
R87 Abnormal findings in specimens from female genital organs
0.751 0.249 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.750 0.250 0.000
Q00-Q07 Congenital malformations of the nervous system
0.750 0.250 0.000
E10.1 With ketoacidosis
0.748 0.251 0.000
I49 Other cardiac arrhythmias
0.746 0.254 0.000
M43.16 Spondylolisthesis (Lumbar region)
0.744 0.256 0.000
M79.60 Pain in limb (Multiple sites)
0.742 0.258 0.000
M30 Polyarteritis nodosa and related conditions
0.742 0.258 0.000
M65 Synovitis and tenosynovitis
0.741 0.259 0.000
W20-W49 Exposure to inanimate mechanical forces
0.741 0.259 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.740 0.260 0.000
M25.5 Pain in joint
0.738 0.262 0.000
G70.0 Myasthenia gravis
0.737 0.263 0.000
G47 Sleep disorders
0.737 0.263 0.000
I72.4 Aneurysm of artery of lower extremity
0.737 0.263 0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.735 0.265 0.000
I95.2 Hypotension due to drugs
0.735 0.265 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.734 0.266 0.000
S86 Injury of muscle and tendon at lower leg level
0.734 0.266 0.000
D80-D89 Certain disorders involving the immune mechanism
0.734 0.266 0.000
I70 Atherosclerosis
0.732 0.268 0.000
D75 Other diseases of blood and blood-forming organs
0.731 0.269 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.730 0.270 0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)
0.730 0.270 0.000
S20-S29 Injuries to the thorax
0.730 0.270 0.000
G71 Primary disorders of muscles
0.728 0.272 0.000
I60-I69 Cerebrovascular diseases
0.726 0.274 0.000
E11.8 With unspecified complications
0.725 0.275 0.000
G47.3 Sleep apnoea
0.725 0.275 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.724 0.276 0.000
M40 Kyphosis and lordosis
0.723 0.277 0.000
G72 Other myopathies
0.722 0.278 0.000
E40-E46 Malnutrition
0.720 0.279 0.000
M43.17 Spondylolisthesis (Lumbosacral region)
0.720 0.280 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.720 0.280 0.000
E28 Ovarian dysfunction
0.720 0.280 0.000
M67 Other disorders of synovium and tendon
0.719 0.281 0.000
M75 Shoulder lesions
0.719 0.281 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.719 0.281 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.719 0.281 0.000
E11.5 With peripheral circulatory complications
0.719 0.281 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
M47.1 Other spondylosis with myelopathy
0.716 0.284 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.716 0.284 0.000
M43.0 Spondylolysis
0.716 0.284 0.000
I73.8 Other specified peripheral vascular diseases
0.715 0.285 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.715 0.285 0.000
E13 Other specified diabetes mellitus
0.715 0.285 0.000
T33-T35 Frostbite
0.715 0.285 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.715 0.285 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.715 0.285 0.000
T00-T07 Injuries involving multiple body regions
0.715 0.285 0.000
M76 Enthesopathies of lower limb, excluding foot
0.714 0.286 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.714 0.286 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.714 0.286 0.000
M47.85 Other spondylosis (Thoracolumbar region)
0.714 0.286 0.000
M47.84 Other spondylosis (Thoracic region)
0.714 0.286 0.000
M47.83 Other spondylosis (Cervicothoracic region)
0.714 0.286 0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.714 0.286 0.000
S82 Fracture of lower leg, including ankle
0.713 0.287 0.000
I36 Nonrheumatic tricuspid valve disorders
0.712 0.288 0.000
M20.2 Hallux rigidus
0.712 0.288 0.000
M79.9 Soft tissue disorder, unspecified
0.711 0.289 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.711 0.289 0.000
M79.3 Panniculitis, unspecified
0.711 0.289 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.711 0.289 0.000
W50-W64 Exposure to animate mechanical forces
0.711 0.289 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.711 0.289 0.000
M89 Other disorders of bone
0.710 0.290 0.000
M79.64 Pain in limb (Hand)
0.709 0.290 0.000
E14.3 With ophthalmic complications
0.709 0.291 0.000
I45.8 Other specified conduction disorders
0.709 0.291 0.000
I77.5 Necrosis of artery
0.709 0.291 0.000
I77.4 Coeliac artery compression syndrome
0.709 0.291 0.000
I77.3 Arterial fibromuscular dysplasia
0.709 0.291 0.000
I77.0 Arteriovenous fistula, acquired
0.709 0.291 0.000
I37 Pulmonary valve disorders
0.708 0.292 0.000
T78 Adverse effects, not elsewhere classified
0.708 0.292 0.000
R93.8 Abnormal findings on diagnostic imaging of other specified body structures
0.707 0.293 0.000
E70-E90 Metabolic disorders
0.706 0.294 0.000
M87 Osteonecrosis
0.706 0.294 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.706 0.294 0.000
T79-T79 Certain early complications of trauma
0.705 0.295 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.704 0.295 0.000
M00-M03 Infectious arthropathies
0.704 0.296 0.000
E24 Cushing's syndrome
0.704 0.296 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.704 0.296 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.703 0.297 0.000
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)
0.703 0.297 0.000
M47.95 Spondylosis, unspecified (Thoracolumbar region)
0.703 0.297 0.000
M47.94 Spondylosis, unspecified (Thoracic region)
0.703 0.297 0.000
M47.93 Spondylosis, unspecified (Cervicothoracic region)
0.703 0.297 0.000
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)
0.703 0.297 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.703 0.297 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.702 0.298 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.702 0.298 0.000
M25.75 Osteophyte (Pelvic region and thigh)
0.702 0.298 0.000
R46 Symptoms and signs involving appearance and behaviour
0.701 0.298 0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation
0.700 0.300 0.000
M71 Other bursopathies
0.700 0.300 0.000
E12 Malnutrition-related diabetes mellitus
0.699 0.301 0.000
M79.68 Pain in limb (Other)
0.699 0.301 0.000
M79.61 Pain in limb (Shoulder region)
0.699 0.301 0.000
E23 Hypofunction and other disorders of pituitary gland
0.699 0.301 0.000
I45.2 Bifascicular block
0.698 0.302 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.698 0.302 0.000
Q50-Q56 Congenital malformations of genital organs
0.697 0.303 0.000
M25.77 Osteophyte (Ankle and foot)
0.696 0.304 0.000
M79.0 Rheumatism, unspecified
0.695 0.305 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.695 0.305 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.695 0.305 0.000
S42.4 Fracture of lower end of humerus
0.695 0.305 0.000
H43-H45 Disorders of vitreous body and globe
0.693 0.307 0.000
R27 Other lack of coordination
0.692 0.308 0.000
I72.3 Aneurysm of iliac artery
0.691 0.308 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.688 0.312 0.000
S50 Superficial injury of forearm
0.688 0.312 0.000
Q80-Q89 Other congenital malformations
0.686 0.313 0.000
I46 Cardiac arrest
0.686 0.314 0.000
R43 Disturbances of smell and taste
0.685 0.315 0.000
R41.3 Other amnesia
0.683 0.317 0.000
I51 Complications and ill-defined descriptions of heart disease
0.682 0.318 0.000
S81 Open wound of lower leg
0.682 0.318 0.000
M43.19 Spondylolisthesis (Site unspecified)
0.681 0.319 0.000
E11.7 With multiple complications
0.681 0.319 0.000
E11.6 With other specified complications
0.681 0.319 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.680 0.320 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.679 0.321 0.000
G12 Spinal muscular atrophy and related syndromes
0.678 0.322 0.000
R87.6 Abnormal cytological findings
0.678 0.322 0.000
D73 Diseases of spleen
0.677 0.322 0.000
M21 Other acquired deformities of limbs
0.677 0.323 0.000
M79.5 Residual foreign body in soft tissue
0.677 0.323 0.000
M42 Spinal osteochondrosis
0.676 0.324 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.676 0.324 0.000
R26 Abnormalities of gait and mobility
0.676 0.324 0.000
M41 Scoliosis
0.676 0.324 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.675 0.325 0.000
I50 Heart failure
0.674 0.326 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.674 0.326 0.000
G90-G99 Other disorders of the nervous system
0.674 0.326 0.000
R21 Rash and other nonspecific skin eruption
0.672 0.328 0.000
G25.3 Myoclonus
0.672 0.328 0.000
I95.8 Other hypotension
0.671 0.328 0.000
I95.0 Idiopathic hypotension
0.671 0.328 0.000
M25.8 Other specified joint disorders
0.671 0.329 0.000
I99 Other and unspecified disorders of circulatory system
0.671 0.329 0.000
M79.78 Fibromyalgia (Other)
0.670 0.330 0.000
M79.77 Fibromyalgia (Ankle and foot)
0.670 0.330 0.000
M79.76 Fibromyalgia (Lower leg)
0.670 0.330 0.000
M79.75 Fibromyalgia (Pelvic region and thigh)
0.670 0.330 0.000
M79.74 Fibromyalgia (Hand)
0.670 0.330 0.000
M79.73 Fibromyalgia (Forearm)
0.670 0.330 0.000
M79.72 Fibromyalgia (Upper arm)
0.670 0.330 0.000
M79.71 Fibromyalgia (Shoulder region)
0.670 0.330 0.000
H11 Other disorders of conjunctiva
0.670 0.330 0.000
M66 Spontaneous rupture of synovium and tendon
0.669 0.331 0.000
M91-M94 Chondropathies
0.668 0.332 0.000
H53.6 Night blindness
0.668 0.332 0.000
H53.5 Colour vision deficiencies
0.668 0.332 0.000
H53.3 Other disorders of binocular vision
0.668 0.332 0.000
I45.6 Preexcitation syndrome
0.668 0.332 0.000
H36 Retinal disorders in diseases classified elsewhere
0.668 0.332 0.000
Chapter VIII Diseases of the ear and mastoid process
0.667 0.333 0.000
I52 Other heart disorders in diseases classified elsewhere
0.666 0.334 0.000
I48 Atrial fibrillation and flutter
0.666 0.334 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.666 0.334 0.000
I41 Myocarditis in diseases classified elsewhere
0.666 0.334 0.000
I40 Acute myocarditis
0.666 0.334 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.666 0.334 0.000
I32 Pericarditis in diseases classified elsewhere
0.666 0.334 0.000
M47.89 Other spondylosis (Site unspecified)
0.666 0.334 0.000
D55-D59 Haemolytic anaemias
0.666 0.334 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.663 0.336 0.000
R49 Voice disturbances
0.663 0.337 0.000
E11.1 With ketoacidosis
0.663 0.337 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.663 0.337 0.000
M75.5 Bursitis of shoulder
0.663 0.337 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.661 0.339 0.000
Q35-Q37 Cleft lip and cleft palate
0.661 0.339 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.661 0.339 0.000
M79.19 Myalgia (Site unspecified)
0.661 0.339 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.660 0.340 0.000
D53 Other nutritional anaemias
0.660 0.340 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.660 0.340 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.659 0.341 0.000
M72 Fibroblastic disorders
0.659 0.341 0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
0.658 0.342 0.000
S10 Superficial injury of neck
0.658 0.342 0.000
F30-F39 Mood [affective] disorders
0.658 0.342 0.000
H46 Optic neuritis
0.658 0.342 0.000
I74.5 Embolism and thrombosis of iliac artery
0.657 0.343 0.000
I78 Diseases of capillaries
0.656 0.343 0.000
I77.8 Other specified disorders of arteries and arterioles
0.655 0.344 0.000
M70.6 Trochanteric bursitis
0.655 0.345 0.000
T18.1 Foreign body in oesophagus
0.654 0.346 0.000
I72.8 Aneurysm of other specified arteries
0.654 0.346 0.000
D50.1 Sideropenic dysphagia
0.653 0.347 0.000
Q76 Congenital malformations of spine and bony thorax
0.653 0.347 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.653 0.347 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.652 0.348 0.000
M47.82 Other spondylosis (Cervical region)
0.652 0.348 0.000
S82.0 Fracture of patella
0.651 0.349 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.649 0.351 0.000
M88 Paget's disease of bone [osteitis deformans]
0.648 0.351 0.000
I77.6 Arteritis, unspecified
0.648 0.352 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.648 0.352 0.000
M33 Dermatopolymyositis
0.648 0.352 0.000
M32 Systemic lupus erythematosus
0.648 0.352 0.000
S48 Traumatic amputation of shoulder and upper arm
0.647 0.353 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.647 0.353 0.000
S44 Injury of nerves at shoulder and upper arm level
0.647 0.353 0.000
S41 Open wound of shoulder and upper arm
0.647 0.353 0.000
S47 Crushing injury of shoulder and upper arm
0.647 0.353 0.000
I42 Cardiomyopathy
0.647 0.353 0.000
I45.4 Nonspecific intraventricular block
0.646 0.354 0.000
I45.3 Trifascicular block
0.646 0.354 0.000
I45.0 Right fascicular block
0.646 0.354 0.000
H53.4 Visual field defects
0.646 0.354 0.000
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere
0.645 0.355 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.645 0.355 0.000
I47.0 Reentry ventricular arrhythmia
0.644 0.356 0.000
T42.4 Benzodiazepines
0.644 0.356 0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs
0.643 0.357 0.000
S70 Superficial injury of hip and thigh
0.643 0.357 0.000
S19 Other and unspecified injuries of neck
0.643 0.357 0.000
I30 Acute pericarditis
0.642 0.358 0.000
S82.1 Fracture of upper end of tibia
0.641 0.359 0.000
M43.9 Deforming dorsopathy, unspecified
0.641 0.359 0.000
M43.8 Other specified deforming dorsopathies
0.641 0.359 0.000
M43.6 Torticollis
0.641 0.359 0.000
M43.5 Other recurrent vertebral subluxation
0.641 0.359 0.000
M43.4 Other recurrent atlantoaxial subluxation
0.641 0.359 0.000
M43.3 Recurrent atlantoaxial subluxation with myelopathy
0.641 0.359 0.000
M43.2 Other fusion of spine
0.641 0.359 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.641 0.359 0.000
Q60-Q64 Congenital malformations of the urinary system
0.640 0.359 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.640 0.360 0.000
M45 Ankylosing spondylitis
0.640 0.360 0.000
S59 Other and unspecified injuries of forearm
0.639 0.361 0.000
S58 Traumatic amputation of forearm
0.639 0.361 0.000
S57 Crushing injury of forearm
0.639 0.361 0.000
S56 Injury of muscle and tendon at forearm level
0.639 0.361 0.000
S55 Injury of blood vessels at forearm level
0.639 0.361 0.000
S54 Injury of nerves at forearm level
0.639 0.361 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.639 0.361 0.000
R45.7 State of emotional shock and stress, unspecified
0.639 0.361 0.000
R45.6 Physical violence
0.639 0.361 0.000
R45.5 Hostility
0.639 0.361 0.000
R45.4 Irritability and anger
0.639 0.361 0.000
R45.3 Demoralisation and apathy
0.639 0.361 0.000
R45.2 Unhappiness
0.639 0.361 0.000
R45.0 Nervousness
0.639 0.361 0.000
T19 Foreign body in genito-urinary tract
0.638 0.361 0.000
T15 Foreign body on external eye
0.638 0.361 0.000
T16 Foreign body in ear
0.638 0.361 0.000
E22 Hyperfunction of pituitary gland
0.638 0.361 0.000
S52.1 Fracture of upper end of radius
0.638 0.362 0.000
E83 Disorders of mineral metabolism
0.638 0.362 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.637 0.363 0.000
W21 Striking against or struck by sports equipment
0.636 0.363 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.635 0.364 0.000
M34 Systemic sclerosis
0.635 0.364 0.000
I49.3 Ventricular premature depolarisation
0.635 0.365 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.635 0.365 0.000
I33 Acute and subacute endocarditis
0.634 0.366 0.000
I61 Intracerebral haemorrhage
0.633 0.367 0.000
G25.2 Other specified forms of tremor
0.633 0.367 0.000
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system
0.633 0.367 0.000
R47 Speech disturbances, not elsewhere classified
0.633 0.367 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.632 0.368 0.000
E34 Other endocrine disorders
0.632 0.368 0.000
E32 Diseases of thymus
0.632 0.368 0.000
E31 Polyglandular dysfunction
0.632 0.368 0.000
E30 Disorders of puberty, not elsewhere classified
0.632 0.368 0.000
E26 Hyperaldosteronism
0.632 0.368 0.000
E25 Adrenogenital disorders
0.632 0.368 0.000
E20 Hypoparathyroidism
0.632 0.368 0.000
M25.52 Pain in joint (Upper arm)
0.631 0.369 0.000
R41.2 Retrograde amnesia
0.630 0.370 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.629 0.371 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.629 0.371 0.000
S42.3 Fracture of shaft of humerus
0.628 0.372 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.628 0.372 0.000
O42 Premature rupture of membranes
0.628 0.372 0.000
M79.18 Myalgia (Other)
0.628 0.372 0.000
G25.0 Essential tremor
0.627 0.373 0.000
Q05 Spina bifida
0.627 0.373 0.000
I72.9 Aneurysm of unspecified site
0.627 0.373 0.000
I72.6 Aneurysm and dissection of vertebral artery
0.627 0.373 0.000
I72.5 Aneurysm and dissection of other precerebral arteries
0.627 0.373 0.000
I72.2 Aneurysm of renal artery
0.627 0.373 0.000
I72.1 Aneurysm of artery of upper extremity
0.627 0.373 0.000
I72.0 Aneurysm of carotid artery
0.627 0.373 0.000
S72 Fracture of femur
0.626 0.373 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.626 0.374 0.000
H59.8 Other postprocedural disorders of eye and adnexa
0.626 0.374 0.000
S32 Fracture of lumbar spine and pelvis
0.626 0.374 0.000
M25.78 Osteophyte (Other)
0.626 0.374 0.000
M30.0 Polyarteritis nodosa
0.625 0.374 0.000
S89 Other and unspecified injuries of lower leg
0.624 0.376 0.000
E11.2 With renal complications
0.624 0.376 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.624 0.376 0.000
I74.8 Embolism and thrombosis of other arteries
0.624 0.376 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.624 0.376 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.624 0.376 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.624 0.376 0.000
M90 Osteopathies in diseases classified elsewhere
0.623 0.376 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.623 0.377 0.000
M79.10 Myalgia (Multiple sites)
0.622 0.378 0.000
F60-F69 Disorders of adult personality and behaviour
0.622 0.378 0.000
R93.6 Abnormal findings on diagnostic imaging of limbs
0.622 0.378 0.000
R85 Abnormal findings in specimens from digestive organs and abdominal cavity
0.622 0.378 0.000
G30 Alzheimer's disease
0.622 0.378 0.000
M79.26 Neuralgia and neuritis, unspecified (Lower leg)
0.621 0.379 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.620 0.380 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.620 0.380 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.620 0.380 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.620 0.380 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.620 0.380 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.620 0.380 0.000
T36 Poisoning by systemic antibiotics
0.620 0.380 0.000
S88 Traumatic amputation of lower leg
0.620 0.380 0.000
S87 Crushing injury of lower leg
0.620 0.380 0.000
S85 Injury of blood vessels at lower leg level
0.620 0.380 0.000
S84 Injury of nerves at lower leg level
0.620 0.380 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.620 0.380 0.000
X60-X84 Intentional self-harm
0.620 0.380 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.619 0.381 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.619 0.381 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.619 0.381 0.000
M25.9 Joint disorder, unspecified
0.618 0.382 0.000
M25.3 Other instability of joint
0.618 0.382 0.000
M25.2 Flail joint
0.618 0.382 0.000
M25.1 Fistula of joint
0.618 0.382 0.000
M25.0 Haemarthrosis
0.618 0.382 0.000
D75.0 Familial erythrocytosis
0.618 0.382 0.000
M65.8 Other synovitis and tenosynovitis
0.618 0.382 0.000
E10.5 With peripheral circulatory complications
0.617 0.383 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.617 0.383 0.000
M05-M14 Inflammatory polyarthropathies
0.617 0.383 0.000
D72 Other disorders of white blood cells
0.617 0.383 0.000
H35 Other retinal disorders
0.617 0.383 0.000
S91 Open wound of ankle and foot
0.616 0.384 0.000
H54 Blindness and low vision
0.615 0.384 0.000
D75.1 Secondary polycythaemia
0.615 0.385 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.615 0.385 0.000
E10.8 With unspecified complications
0.615 0.385 0.000
E10.7 With multiple complications
0.615 0.385 0.000
E10.6 With other specified complications
0.615 0.385 0.000
E10.2 With renal complications
0.615 0.385 0.000
E10.0 With coma
0.615 0.385 0.000
S42.9 Fracture of shoulder girdle, part unspecified
0.615 0.385 0.000
S42.8 Fracture of other parts of shoulder and upper arm
0.615 0.385 0.000
S42.7 Multiple fractures of clavicle, scapula and humerus
0.615 0.385 0.000
M31 Other necrotising vasculopathies
0.614 0.385 0.000
M47.2 Other spondylosis with radiculopathy
0.614 0.386 0.000
R27.0 Ataxia, unspecified
0.614 0.386 0.000
S80 Superficial injury of lower leg
0.613 0.387 0.000
W00-W19 Falls
0.612 0.388 0.000
S52.7 Multiple fractures of forearm
0.612 0.388 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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