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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2857114
log Bayes Factor = 35.3309
Chromosome 6   position 32,779,996  (GRCh37) Explore rs2857114 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
C44 Other malignant neoplasms of skin
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
C44.7 Skin of lower limb, including hip
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
E20-E35 Disorders of other endocrine glands
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.001 0.999
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.001 0.999
C44.3 Skin of other and unspecified parts of face
0.000 0.002 0.998
C44.6 Skin of upper limb, including shoulder
0.000 0.002 0.998
E05.9 Thyrotoxicosis, unspecified
0.000 0.004 0.996
E27 Other disorders of adrenal gland
0.000 0.010 0.990
E23 Hypofunction and other disorders of pituitary gland
0.000 0.015 0.985
E83.1 Disorders of iron metabolism
0.982 0.018 0.000
L57.0 Actinic keratosis
0.000 0.018 0.982
E10.9 Without complications
0.000 0.023 0.977
E27.1 Primary adrenocortical insufficiency
0.000 0.032 0.968
C44.4 Skin of scalp and neck
0.000 0.034 0.966
G35-G37 Demyelinating diseases of the central nervous system
0.957 0.043 0.000
G37 Other demyelinating diseases of central nervous system
0.944 0.056 0.000
E23.7 Disorder of pituitary gland, unspecified
0.000 0.063 0.937
E10.2 With renal complications
0.000 0.064 0.936
E10.1 With ketoacidosis
0.000 0.067 0.933
E10.5 With peripheral circulatory complications
0.000 0.076 0.924
E23.6 Other disorders of pituitary gland
0.000 0.077 0.923
G37.9 Demyelinating disease of central nervous system, unspecified
0.918 0.082 0.000
E24 Cushing's syndrome
0.000 0.085 0.915
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.102 0.898
C44.2 Skin of ear and external auricular canal
0.000 0.105 0.895
G37.8 Other specified demyelinating diseases of central nervous system
0.872 0.128 0.000
C44.0 Skin of lip
0.000 0.132 0.868
L40-L45 Papulosquamous disorders
0.000 0.155 0.845
M07.3 Other psoriatic arthropathies
0.000 0.160 0.840
L40.1 Generalised pustular psoriasis
0.000 0.162 0.838
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.163 0.837
E06 Thyroiditis
0.000 0.163 0.836
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.168 0.832
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.177 0.823
L40.0 Psoriasis vulgaris
0.000 0.182 0.818
E11 Non-insulin-dependent diabetes mellitus
0.000 0.187 0.813
L40.3 Pustulosis palmaris et plantaris
0.000 0.187 0.813
E10.4 With neurological complications
0.000 0.193 0.807
E29 Testicular dysfunction
0.000 0.198 0.802
E10.0 With coma
0.000 0.200 0.800
E28 Ovarian dysfunction
0.000 0.207 0.793
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.207 0.793
E11.3 With ophthalmic complications
0.000 0.209 0.791
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.221 0.779
L40.4 Guttate psoriasis
0.000 0.222 0.778
G36 Other acute disseminated demyelination
0.775 0.225 0.000
E13 Other specified diabetes mellitus
0.000 0.231 0.769
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.235 0.765
E24.0 Pituitary-dependent Cushing's disease
0.000 0.235 0.765
E24.2 Drug-induced Cushing's syndrome
0.000 0.241 0.759
E23.0 Hypopituitarism
0.000 0.246 0.754
E06.3 Autoimmune thyroiditis
0.000 0.253 0.747
E26 Hyperaldosteronism
0.000 0.255 0.745
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.270 0.730
E24.9 Cushing's syndrome, unspecified
0.000 0.272 0.728
L43 Lichen planus
0.000 0.281 0.719
E10.7 With multiple complications
0.000 0.283 0.717
C44.8 Overlapping lesion of skin
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.283 0.717
E32 Diseases of thymus
0.000 0.283 0.717
E31 Polyglandular dysfunction
0.000 0.283 0.717
E30 Disorders of puberty, not elsewhere classified
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E04 Other non-toxic goitre
0.000 0.283 0.717
E27.5 Adrenomedullary hyperfunction
0.000 0.290 0.710
E27.0 Other adrenocortical overactivity
0.000 0.290 0.710
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.291 0.709
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.294 0.706
E23.1 Drug-induced hypopituitarism
0.000 0.294 0.706
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.296 0.704
E11.2 With renal complications
0.000 0.297 0.703
E27.2 Addisonian crisis
0.000 0.310 0.690
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.315 0.685
E05.8 Other thyrotoxicosis
0.000 0.319 0.681
E27.8 Other specified disorders of adrenal gland
0.000 0.320 0.680
E25 Adrenogenital disorders
0.000 0.321 0.679
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.321 0.679
E10.6 With other specified complications
0.000 0.322 0.678
G37.5 Concentric sclerosis [Balo]
0.677 0.323 0.000
G37.4 Subacute necrotising myelitis
0.677 0.323 0.000
G37.2 Central pontine myelinolysis
0.677 0.323 0.000
G37.1 Central demyelination of corpus callosum
0.677 0.323 0.000
G37.0 Diffuse sclerosis
0.677 0.323 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.326 0.674
E24.8 Other Cushing's syndrome
0.000 0.328 0.672
E65-E68 Obesity and other hyperalimentation
0.000 0.330 0.670
E29.1 Testicular hypofunction
0.000 0.339 0.661
E23.2 Diabetes insipidus
0.000 0.343 0.657
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.344 0.656
E24.3 Ectopic ACTH syndrome
0.000 0.344 0.656
E24.1 Nelson's syndrome
0.000 0.344 0.656
G36.0 Neuromyelitis optica [Devic]
0.645 0.355 0.000
E04.0 Non-toxic diffuse goitre
0.000 0.357 0.643
C43-C44 Melanoma and other malignant neoplasms of skin
0.000 0.360 0.640
E11.0 With coma
0.000 0.365 0.635
E28.2 Polycystic ovarian syndrome
0.000 0.370 0.630
E34 Other endocrine disorders
0.000 0.372 0.628
E27.9 Disorder of adrenal gland, unspecified
0.000 0.372 0.628
E06.9 Thyroiditis, unspecified
0.000 0.374 0.625
E40-E46 Malnutrition
0.000 0.379 0.621
L43.9 Lichen planus, unspecified
0.000 0.382 0.618
E20 Hypoparathyroidism
0.000 0.386 0.614
L44 Other papulosquamous disorders
0.000 0.394 0.606
L41 Parapsoriasis
0.000 0.394 0.606
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.394 0.606
M07.38 Other psoriatic arthropathies (Other)
0.000 0.398 0.602
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.398 0.602
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.398 0.602
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.398 0.602
E06.4 Drug-induced thyroiditis
0.000 0.400 0.600
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.400 0.600
E06.0 Acute thyroiditis
0.000 0.400 0.600
E06.5 Other chronic thyroiditis
0.000 0.404 0.596
E28.3 Primary ovarian failure
0.000 0.410 0.590
E13.9 Without complications
0.000 0.413 0.587
E11.7 With multiple complications
0.000 0.417 0.583
E65 Localised adiposity
0.000 0.418 0.582
E10.8 With unspecified complications
0.000 0.420 0.580
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.576 0.424 0.000
E04.2 Non-toxic multinodular goitre
0.000 0.424 0.576
E22 Hyperfunction of pituitary gland
0.000 0.424 0.576
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.000 0.424 0.575
E29.9 Testicular dysfunction, unspecified
0.000 0.425 0.575
E29.8 Other testicular dysfunction
0.000 0.425 0.575
E29.0 Testicular hyperfunction
0.000 0.425 0.575
E13.3 With ophthalmic complications
0.000 0.429 0.571
E28.9 Ovarian dysfunction, unspecified
0.000 0.431 0.569
E28.8 Other ovarian dysfunction
0.000 0.431 0.569
E28.1 Androgen excess
0.000 0.431 0.569
E28.0 Oestrogen excess
0.000 0.431 0.569
L57.5 Actinic granuloma
0.000 0.432 0.568
L57.3 Poikiloderma of Civatte
0.000 0.432 0.568
L57.2 Cutis rhomboidalis nuchae
0.000 0.432 0.568
L57.1 Actinic reticuloid
0.000 0.432 0.568
E11.8 With unspecified complications
0.000 0.435 0.565
E26.0 Primary hyperaldosteronism
0.000 0.437 0.563
E11.6 With other specified complications
0.000 0.441 0.559
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.442 0.558
G36.9 Acute disseminated demyelination, unspecified
0.556 0.444 0.000
G36.8 Other specified acute disseminated demyelination
0.556 0.444 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.556 0.444 0.000
E13.8 With unspecified complications
0.000 0.449 0.551
E13.7 With multiple complications
0.000 0.449 0.551
E13.6 With other specified complications
0.000 0.449 0.551
E13.5 With peripheral circulatory complications
0.000 0.449 0.551
E13.4 With neurological complications
0.000 0.449 0.551
E13.2 With renal complications
0.000 0.449 0.551
E13.1 With ketoacidosis
0.000 0.449 0.551
E13.0 With coma
0.000 0.449 0.551
L40.8 Other psoriasis
0.000 0.452 0.548
L43.8 Other lichen planus
0.000 0.464 0.536
E26.9 Hyperaldosteronism, unspecified
0.000 0.466 0.534
E26.8 Other hyperaldosteronism
0.000 0.466 0.534
E26.1 Secondary hyperaldosteronism
0.000 0.466 0.534
L42 Pityriasis rosea
0.000 0.468 0.532
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.000 0.476 0.524
L55 Sunburn
0.000 0.476 0.523
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.482 0.517
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.483 0.517
L43.3 Subacute (active) lichen planus
0.000 0.484 0.515
L43.2 Lichenoid drug reaction
0.000 0.484 0.515
L43.1 Bullous lichen planus
0.000 0.484 0.515
L43.0 Hypertrophic lichen planus
0.000 0.484 0.515
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E30.9 Disorder of puberty, unspecified
0.000 0.486 0.514
E30.8 Other disorders of puberty
0.000 0.486 0.514
E30.1 Precocious puberty
0.000 0.486 0.514
E30.0 Delayed puberty
0.000 0.486 0.514
E31.9 Polyglandular dysfunction, unspecified
0.000 0.486 0.514
E31.8 Other polyglandular dysfunction
0.000 0.486 0.514
E31.1 Polyglandular hyperfunction
0.000 0.486 0.514
E31.0 Autoimmune polyglandular failure
0.000 0.486 0.514
E32.9 Disease of thymus, unspecified
0.000 0.486 0.514
E32.8 Other diseases of thymus
0.000 0.486 0.514
E32.1 Abscess of thymus
0.000 0.486 0.514
E32.0 Persistent hyperplasia of thymus
0.000 0.486 0.514
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.486 0.514
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.486 0.514
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E04.8 Other specified non-toxic goitre
0.000 0.486 0.514
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.488 0.512
E34.8 Other specified endocrine disorders
0.000 0.491 0.509
E11.5 With peripheral circulatory complications
0.000 0.493 0.507
E15 Nondiabetic hypoglycaemic coma
0.000 0.495 0.505
E21.3 Hyperparathyroidism, unspecified
0.000 0.499 0.501
E06.1 Subacute thyroiditis
0.000 0.506 0.493
L10-L14 Bullous disorders
0.000 0.506 0.494
E16 Other disorders of pancreatic internal secretion
0.000 0.509 0.491
E25.9 Adrenogenital disorder, unspecified
0.000 0.513 0.487
E25.8 Other adrenogenital disorders
0.000 0.513 0.487
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.000 0.516 0.484
E21.4 Other specified disorders of parathyroid gland
0.000 0.517 0.483
L58 Radiodermatitis
0.000 0.517 0.483
E67 Other hyperalimentation
0.000 0.520 0.480
E68 Sequelae of hyperalimentation
0.000 0.520 0.480
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.529 0.471
E07 Other disorders of thyroid
0.000 0.531 0.469
E21.2 Other hyperparathyroidism
0.000 0.535 0.465
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.000 0.543 0.457
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.000 0.546 0.454
E04.9 Non-toxic goitre, unspecified
0.000 0.547 0.453
E34.5 Androgen resistance syndrome
0.000 0.549 0.451
E34.4 Constitutional tall stature
0.000 0.549 0.451
E34.3 Short stature, not elsewhere classified
0.000 0.549 0.451
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.549 0.451
E34.1 Other hypersecretion of intestinal hormones
0.000 0.549 0.451
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.551 0.449
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.000 0.552 0.448
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.555 0.445
E45 Retarded development following protein-energy malnutrition
0.000 0.555 0.445
E43 Unspecified severe protein-energy malnutrition
0.000 0.555 0.445
E42 Marasmic kwashiorkor
0.000 0.555 0.445
E41 Nutritional marasmus
0.000 0.555 0.445
E40 Kwashiorkor
0.000 0.555 0.445
Chapter II Neoplasms
0.000 0.558 0.442
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.000 0.558 0.442
E20.1 Pseudohypoparathyroidism
0.000 0.560 0.440
E20.0 Idiopathic hypoparathyroidism
0.000 0.560 0.440
D37-D48 Neoplasms of uncertain or unknown behaviour
0.000 0.565 0.435
L41.9 Parapsoriasis, unspecified
0.000 0.565 0.435
L41.8 Other parapsoriasis
0.000 0.565 0.435
L41.5 Retiform parapsoriasis
0.000 0.565 0.435
L41.4 Large plaque parapsoriasis
0.000 0.565 0.435
L41.3 Small plaque parapsoriasis
0.000 0.565 0.435
L41.2 Lymphomatoid papulosis
0.000 0.565 0.435
L41.1 Pityriasis lichenoides chronica
0.000 0.565 0.435
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.565 0.435
L44.9 Papulosquamous disorder, unspecified
0.000 0.565 0.435
L44.8 Other specified papulosquamous disorders
0.000 0.565 0.435
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.565 0.435
L44.3 Lichen ruber moniliformis
0.000 0.565 0.435
L44.2 Lichen striatus
0.000 0.565 0.435
L44.1 Lichen nitidus
0.000 0.565 0.435
L44.0 Pityriasis rubra pilaris
0.000 0.565 0.435
L56.8 Other specified acute skin changes due to ultraviolet radiation
0.000 0.567 0.433
L56.9 Acute skin change due to ultraviolet radiation, unspecified
0.000 0.569 0.431
L57.4 Cutis laxa senilis
0.000 0.573 0.427
E11.1 With ketoacidosis
0.000 0.582 0.418
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.000 0.582 0.418
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.000 0.585 0.415
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.000 0.586 0.414
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.587 0.413
E22.8 Other hyperfunction of pituitary gland
0.000 0.587 0.413
E22.1 Hyperprolactinaemia
0.000 0.588 0.412
E20.9 Hypoparathyroidism, unspecified
0.000 0.588 0.412
E21.0 Primary hyperparathyroidism
0.000 0.589 0.411
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.000 0.593 0.407
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.596 0.404
E70-E90 Metabolic disorders
0.000 0.596 0.404
C43 Malignant melanoma of skin
0.000 0.597 0.403
L56.3 Solar urticaria
0.000 0.600 0.400
L56.2 Photocontact dermatitis [berloque dermatitis]
0.000 0.600 0.400
L56.1 Drug photoallergic response
0.000 0.600 0.400
L56.0 Drug phototoxic response
0.000 0.600 0.400
C73 Malignant neoplasm of thyroid gland
0.000 0.602 0.398
C85.1 B-cell lymphoma, unspecified
0.000 0.602 0.398
D43.0 Brain, supratentorial
0.000 0.604 0.396
C82.0 Small cleaved cell, follicular
0.000 0.606 0.394
C83 Diffuse non-Hodgkin's lymphoma
0.000 0.606 0.394
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.000 0.615 0.385
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.616 0.384
C43.3 Malignant melanoma of other and unspecified parts of face
0.000 0.617 0.383
D47.2 Monoclonal gammopathy
0.000 0.617 0.383
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.620 0.380
C44.9 Malignant neoplasm of skin, unspecified
0.001 0.620 0.379
D00-D09 In situ neoplasms
0.000 0.621 0.379
L12 Pemphigoid
0.000 0.621 0.379
D04 Carcinoma in situ of skin
0.000 0.623 0.377
E20.8 Other hypoparathyroidism
0.000 0.624 0.376
L59.8 Other specified disorders of skin and subcutaneous tissue related to radiation
0.000 0.624 0.376
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.000 0.624 0.376
L59.9 Disorder of skin and subcutaneous tissue related to radiation, unspecified
0.000 0.624 0.376
L59.0 Erythema ab igne [dermatitis ab igne]
0.000 0.624 0.376
L55.9 Sunburn, unspecified
0.000 0.624 0.375
L55.8 Other sunburn
0.000 0.624 0.375
L55.2 Sunburn of third degree
0.000 0.624 0.375
L55.1 Sunburn of second degree
0.000 0.624 0.375
L55.0 Sunburn of first degree
0.000 0.624 0.375
E34.9 Endocrine disorder, unspecified
0.000 0.627 0.373
E78.2 Mixed hyperlipidaemia
0.000 0.629 0.371
C91 Lymphoid leukaemia
0.000 0.632 0.368
C83.3 Large cell (diffuse)
0.000 0.633 0.367
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.634 0.366
L56.4 Polymorphous light eruption
0.000 0.635 0.364
C88 Malignant immunoproliferative diseases
0.000 0.636 0.364
L11 Other acantholytic disorders
0.000 0.642 0.357
L10 Pemphigus
0.000 0.646 0.354
L14 Bullous disorders in diseases classified elsewhere
0.000 0.646 0.354
J45.9 Asthma, unspecified
0.354 0.646 0.000
D43.2 Brain, unspecified
0.000 0.646 0.354
E34.0 Carcinoid syndrome
0.000 0.647 0.352
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.648 0.352
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.648 0.352
E16.4 Abnormal secretion of gastrin
0.000 0.648 0.352
E16.3 Increased secretion of glucagon
0.000 0.648 0.352
C44.5 Skin of trunk
0.000 0.648 0.352
D04.5 Skin of trunk
0.000 0.650 0.350
E46 Unspecified protein-energy malnutrition
0.000 0.651 0.349
C82.4 Follicular lymphoma grade IIIb
0.000 0.651 0.348
D45 Polycythaemia vera
0.000 0.653 0.347
L58.1 Chronic radiodermatitis
0.000 0.654 0.346
L58.0 Acute radiodermatitis
0.000 0.654 0.346
C84 Peripheral and cutaneous T-cell lymphomas
0.000 0.654 0.346
E67.8 Other specified hyperalimentation
0.000 0.655 0.344
E67.3 Hypervitaminosis D
0.000 0.655 0.344
E67.2 Megavitamin-B6 syndrome
0.000 0.655 0.344
E67.1 Hypercarotenaemia
0.000 0.655 0.344
E67.0 Hypervitaminosis A
0.000 0.655 0.344
C02 Malignant neoplasm of other and unspecified parts of tongue
0.000 0.656 0.344
D47.3 Essential (haemorrhagic) thrombocythaemia
0.000 0.657 0.343
C82.2 Large cell, follicular
0.000 0.657 0.343
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.000 0.662 0.338
C91.9 Lymphoid leukaemia, unspecified
0.000 0.663 0.337
E07.1 Dyshormogenetic goitre
0.000 0.663 0.336
E07.0 Hypersecretion of calcitonin
0.000 0.663 0.336
C12 Malignant neoplasm of pyriform sinus
0.000 0.664 0.336
D06 Carcinoma in situ of cervix uteri
0.000 0.664 0.336
D04.3 Skin of other and unspecified parts of face
0.000 0.666 0.334
E78.6 Lipoprotein deficiency
0.000 0.666 0.334
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.000 0.666 0.334
L60-L75 Disorders of skin appendages
0.000 0.667 0.333
D40.0 Prostate
0.000 0.667 0.333
E16.1 Other hypoglycaemia
0.000 0.668 0.332
D48.5 Skin
0.000 0.668 0.332
E88 Other metabolic disorders
0.000 0.669 0.331
D46 Myelodysplastic syndromes
0.000 0.669 0.331
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified
0.000 0.670 0.330
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.000 0.671 0.329
E89.0 Postprocedural hypothyroidism
0.000 0.671 0.329
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.000 0.672 0.328
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.672 0.327
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.000 0.675 0.325
C85.0 Lymphosarcoma
0.000 0.675 0.325
E16.2 Hypoglycaemia, unspecified
0.000 0.675 0.325
M07 Psoriatic and enteropathic arthropathies
0.000 0.677 0.323
C90 Multiple myeloma and malignant plasma cell neoplasms
0.000 0.677 0.323
C82.1 Mixed small cleaved and large cell, follicular
0.000 0.677 0.322
E78.5 Hyperlipidaemia, unspecified
0.000 0.678 0.322
L13 Other bullous disorders
0.000 0.678 0.321
C93 Monocytic leukaemia
0.000 0.680 0.320
E44.1 Mild protein-energy malnutrition
0.000 0.681 0.319
E44.0 Moderate protein-energy malnutrition
0.000 0.681 0.319
E78.1 Pure hyperglyceridaemia
0.000 0.683 0.317
C82.6 Cutaneous follicle centre lymphoma
0.000 0.683 0.317
C82.5 Diffuse follicle centre lymphoma
0.000 0.683 0.317
E07.8 Other specified disorders of thyroid
0.000 0.683 0.316
D06.9 Cervix, unspecified
0.000 0.684 0.316
D04.2 Skin of ear and external auricular canal
0.000 0.685 0.315
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.000 0.686 0.314
C02.9 Tongue, unspecified
0.000 0.687 0.313
C95 Leukaemia of unspecified cell type
0.000 0.687 0.313
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.000 0.687 0.313
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.000 0.688 0.312
E11.4 With neurological complications
0.000 0.689 0.311
C43.6 Malignant melanoma of upper limb, including shoulder
0.000 0.689 0.311
C83.7 Burkitt's tumour
0.000 0.689 0.311
C94 Other leukaemias of specified cell type
0.000 0.691 0.309
C11 Malignant neoplasm of nasopharynx
0.000 0.692 0.308
J45 Asthma
0.308 0.692 0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.000 0.694 0.306
L58.9 Radiodermatitis, unspecified
0.000 0.694 0.305
C83.1 Small cleaved cell (diffuse)
0.000 0.695 0.305
E89.3 Postprocedural hypopituitarism
0.000 0.695 0.305
C85.7 Other specified types of non-Hodgkin's lymphoma
0.000 0.697 0.303
C03 Malignant neoplasm of gum
0.000 0.697 0.303
C86 Other specified types of T/NK-cell lymphoma
0.000 0.698 0.302
C08 Malignant neoplasm of other and unspecified major salivary glands
0.000 0.698 0.302
E79 Disorders of purine and pyrimidine metabolism
0.000 0.699 0.300
D43.1 Brain, infratentorial
0.000 0.700 0.300
D43.9 Central nervous system, unspecified
0.000 0.700 0.300
D43.7 Other parts of central nervous system
0.000 0.700 0.300
D43.3 Cranial nerves
0.000 0.700 0.300
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.700 0.300
C81 Hodgkin's disease
0.000 0.701 0.299
C07 Malignant neoplasm of parotid gland
0.000 0.702 0.298
C84.5 Other and unspecified T-cell lymphomas
0.000 0.703 0.297
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.000 0.703 0.297
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]
0.000 0.703 0.297
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour
0.000 0.703 0.297
J45.0 Predominantly allergic asthma
0.297 0.703 0.000
C75 Malignant neoplasm of other endocrine glands and related structures
0.000 0.704 0.296
D43.4 Spinal cord
0.000 0.705 0.295
L71 Rosacea
0.000 0.707 0.293
D04.4 Skin of scalp and neck
0.000 0.707 0.293
D40.1 Testis
0.000 0.708 0.292
L12.9 Pemphigoid, unspecified
0.000 0.708 0.292
D47.4 Osteomyelofibrosis
0.000 0.708 0.292
E84 Cystic fibrosis
0.000 0.709 0.291
E77 Disorders of glycoprotein metabolism
0.000 0.710 0.290
E76 Disorders of glycosaminoglycan metabolism
0.000 0.710 0.290
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.710 0.290
E70 Disorders of aromatic amino-acid metabolism
0.000 0.710 0.290
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.710 0.290
C43.8 Overlapping malignant melanoma of skin
0.000 0.711 0.289
C43.0 Malignant melanoma of lip
0.000 0.711 0.289
E22.0 Acromegaly and pituitary gigantism
0.000 0.711 0.289
D47.1 Chronic myeloproliferative disease
0.000 0.711 0.289
C04 Malignant neoplasm of floor of mouth
0.000 0.713 0.287
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.715 0.285
D04.7 Skin of lower limb, including hip
0.000 0.717 0.283
C83.6 Undifferentiated (diffuse)
0.000 0.718 0.282
C83.4 Immunoblastic (diffuse)
0.000 0.718 0.282
C83.2 Mixed small and large cell (diffuse)
0.000 0.718 0.282
C91.5 Adult T-cell leukaemia
0.000 0.718 0.282
L50-L54 Urticaria and erythema
0.000 0.718 0.282
D04.9 Skin, unspecified
0.000 0.718 0.281
C74 Malignant neoplasm of adrenal gland
0.000 0.719 0.281
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.719 0.281
C05 Malignant neoplasm of palate
0.000 0.720 0.280
C43.2 Malignant melanoma of ear and external auricular canal
0.000 0.720 0.280
C43.9 Malignant melanoma of skin, unspecified
0.000 0.720 0.280
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.000 0.722 0.278
C02.2 Ventral surface of tongue
0.000 0.722 0.278
E88.3 Tumour lysis syndrome
0.000 0.723 0.277
L12.1 Cicatricial pemphigoid
0.000 0.724 0.276
D01 Carcinoma in situ of other and unspecified digestive organs
0.000 0.725 0.275
L12.0 Bullous pemphigoid
0.000 0.726 0.274
C91.0 Acute lymphoblastic leukaemia
0.000 0.726 0.274
E50-E64 Other nutritional deficiencies
0.000 0.728 0.272
L12.8 Other pemphigoid
0.000 0.728 0.272
L12.3 Acquired epidermolysis bullosa
0.000 0.728 0.272
L12.2 Chronic bullous disease of childhood
0.000 0.728 0.272
D04.6 Skin of upper limb, including shoulder
0.000 0.728 0.272
E03 Other hypothyroidism
0.000 0.729 0.271
D04.8 Skin of other sites
0.000 0.730 0.270
D04.0 Skin of lip
0.000 0.730 0.270
D40.9 Male genital organ, unspecified
0.000 0.730 0.270
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.000 0.731 0.269
D38.1 Trachea, bronchus and lung
0.000 0.731 0.269
L68 Hypertrichosis
0.000 0.732 0.268
C91.4 Hairy-cell leukaemia
0.000 0.732 0.268
D04.1 Skin of eyelid, including canthus
0.000 0.732 0.267
C13 Malignant neoplasm of hypopharynx
0.000 0.734 0.266
C40-C41 Malignant neoplasms of bone and articular cartilage
0.000 0.735 0.264
C91.8 Mature B-cell leukaemia Burkitt-type
0.000 0.736 0.264
C91.7 Other lymphoid leukaemia
0.000 0.736 0.264
C91.6 Prolymphocytic leukaemia of T-cell type
0.000 0.736 0.264
C91.3 Prolymphocytic leukaemia
0.000 0.736 0.264
C91.2 Subacute lymphocytic leukaemia
0.000 0.736 0.264
L11.0 Acquired keratosis follicularis
0.000 0.736 0.264
C82.3 Follicular lymphoma grade IIIa
0.000 0.737 0.262
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.737 0.262
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.737 0.262
E89.5 Postprocedural testicular hypofunction
0.000 0.737 0.262
C88.9 Malignant immunoproliferative disease, unspecified
0.000 0.739 0.261
C88.7 Other malignant immunoproliferative diseases
0.000 0.739 0.261
C88.3 Immunoproliferative small intestinal disease
0.000 0.739 0.261
C88.2 Gamma heavy chain disease
0.000 0.739 0.261
C88.1 Alpha heavy chain disease
0.000 0.739 0.261
C83.5 Lymphoblastic (diffuse)
0.000 0.739 0.260
E88.8 Other specified metabolic disorders
0.000 0.741 0.259
C90.2 Plasmacytoma, extramedullary
0.000 0.741 0.259
C43.4 Malignant melanoma of scalp and neck
0.000 0.742 0.258
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.000 0.742 0.258
E88.2 Lipomatosis, not elsewhere classified
0.000 0.742 0.257
D46.2 Refractory anaemia with excess of blasts
0.000 0.743 0.257
L11.9 Acantholytic disorder, unspecified
0.000 0.743 0.256
L11.8 Other specified acantholytic disorders
0.000 0.743 0.256
D44.4 Craniopharyngeal duct
0.000 0.744 0.256
E78.4 Other hyperlipidaemia
0.000 0.744 0.256
C97 Malignant neoplasms of independent (primary) multiple sites
0.000 0.744 0.256
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.744 0.256
L71.9 Rosacea, unspecified
0.000 0.744 0.256
D09 Carcinoma in situ of other and unspecified sites
0.000 0.745 0.255
E89.4 Postprocedural ovarian failure
0.000 0.745 0.255

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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