TreeWAS – Variant ID: rs28780100

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Showing all nodes without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	0.000	0.000	1.000
L40.9 Psoriasis, unspecified	1.000	0.000	0.000
L40.5 Arthropathic psoriasis	1.000	0.000	0.000
L40 Psoriasis	1.000	0.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	1.000	0.000	0.000
Chapter VI Diseases of the nervous system	1.000	0.000	0.000
I20-I25 Ischaemic heart diseases	1.000	0.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.999	0.001	0.000
Chapter IX Diseases of the circulatory system	0.999	0.001	0.000
L40-L45 Papulosquamous disorders	0.997	0.003	0.000
G40-G47 Episodic and paroxysmal disorders	0.997	0.003	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.996	0.004	0.000
M07.3 Other psoriatic arthropathies	0.996	0.004	0.000
M07 Psoriatic and enteropathic arthropathies	0.996	0.004	0.000
M05-M14 Inflammatory polyarthropathies	0.996	0.004	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.994	0.006	0.000
Chapter XIV Diseases of the genitourinary system	0.993	0.007	0.000
N20 Calculus of kidney and ureter	0.992	0.008	0.000
N20-N23 Urolithiasis	0.992	0.008	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.990	0.009	0.001
Chapter XX External causes of morbidity and mortality	0.990	0.010	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.989	0.011	0.000
G40 Epilepsy	0.989	0.011	0.000
T43.2 Other and unspecified antidepressants	0.986	0.014	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.986	0.014	0.000
N20.1 Calculus of ureter	0.985	0.015	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.985	0.015	0.000
Chapter V Mental and behavioural disorders	0.985	0.015	0.000
E70-E90 Metabolic disorders	0.982	0.018	0.000
I24 Other acute ischaemic heart diseases	0.982	0.018	0.000
N10-N16 Renal tubulo-interstitial diseases	0.981	0.019	0.000
I20 Angina pectoris	0.981	0.019	0.000
N20.0 Calculus of kidney	0.980	0.020	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.979	0.021	0.000
E78.0 Pure hypercholesterolaemia	0.979	0.021	0.000
I60-I69 Cerebrovascular diseases	0.972	0.028	0.000
N13 Obstructive and reflux uropathy	0.972	0.028	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.970	0.030	0.000
I20.0 Unstable angina	0.969	0.031	0.000
E03 Other hypothyroidism	0.008	0.032	0.960
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.964	0.036	0.000
G62 Other polyneuropathies	0.962	0.038	0.000
I24.8 Other forms of acute ischaemic heart disease	0.962	0.038	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.958	0.042	0.000
W20-W49 Exposure to inanimate mechanical forces	0.958	0.042	0.000
G45 Transient cerebral ischaemic attacks and related syndromes	0.957	0.043	0.000
F17 Mental and behavioural disorders due to use of tobacco	0.955	0.045	0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.954	0.046	0.000
F17.1 Harmful use	0.953	0.047	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.952	0.048	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.951	0.049	0.000
I21 Acute myocardial infarction	0.951	0.049	0.000
E00-E07 Disorders of thyroid gland	0.019	0.050	0.932
I25 Chronic ischaemic heart disease	0.949	0.051	0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.949	0.051	0.000
Y43 Primarily systemic agents	0.948	0.052	0.000
I21.4 Acute subendocardial myocardial infarction	0.941	0.059	0.000
M45-M49 Spondylopathies	0.940	0.060	0.000
T39.1 4-Aminophenol derivatives	0.939	0.061	0.000
K90.0 Coeliac disease	0.000	0.061	0.939
Y43.3 Other antineoplastic drugs	0.938	0.062	0.000
W22 Striking against or struck by other objects	0.935	0.065	0.000
J47 Bronchiectasis	0.000	0.073	0.927
E05 Thyrotoxicosis [hyperthyroidism]	0.006	0.076	0.918
G62.9 Polyneuropathy, unspecified	0.920	0.080	0.000
W22.9 Unspecified place	0.919	0.081	0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.917	0.083	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.914	0.086	0.000
Chapter XI Diseases of the digestive system	0.913	0.087	0.000
I67 Other cerebrovascular diseases	0.912	0.088	0.000
L40.0 Psoriasis vulgaris	0.912	0.088	0.000
J40-J47 Chronic lower respiratory diseases	0.000	0.088	0.912
G20-G26 Extrapyramidal and movement disorders	0.910	0.090	0.000
K80 Cholelithiasis	0.910	0.090	0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.909	0.091	0.000
G45.9 Transient cerebral ischaemic attack, unspecified	0.906	0.094	0.000
J45 Asthma	0.000	0.097	0.903
E05.9 Thyrotoxicosis, unspecified	0.001	0.098	0.901
K80.0 Calculus of gallbladder with acute cholecystitis	0.901	0.099	0.000
E20-E35 Disorders of other endocrine glands	0.899	0.101	0.000
K70-K77 Diseases of liver	0.896	0.104	0.000
J45.9 Asthma, unspecified	0.000	0.105	0.895
N13.9 Obstructive and reflux uropathy, unspecified	0.891	0.109	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.887	0.113	0.000
S32 Fracture of lumbar spine and pelvis	0.883	0.117	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.882	0.118	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.882	0.118	0.000
M20-M25 Other joint disorders	0.879	0.121	0.000
K80.1 Calculus of gallbladder with other cholecystitis	0.879	0.121	0.000
M47 Spondylosis	0.875	0.125	0.000
F30-F39 Mood [affective] disorders	0.871	0.129	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.869	0.131	0.000
S80-S89 Injuries to the knee and lower leg	0.863	0.137	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.861	0.139	0.000
M47.8 Other spondylosis	0.860	0.140	0.000
G62.8 Other specified polyneuropathies	0.857	0.143	0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures	0.857	0.143	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.857	0.143	0.000
K80.4 Calculus of bile duct with cholecystitis	0.855	0.145	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.855	0.145	0.000
N13.6 Pyonephrosis	0.854	0.146	0.000
M40-M43 Deforming dorsopathies	0.853	0.147	0.000
E87 Other disorders of fluid, electrolyte and acid-base balance	0.851	0.149	0.000
S10-S19 Injuries to the neck	0.851	0.149	0.000
M47.82 Other spondylosis (Cervical region)	0.850	0.150	0.000
M25 Other joint disorders, not elsewhere classified	0.846	0.154	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.845	0.155	0.000
G24 Dystonia	0.842	0.158	0.000
I67.1 Cerebral aneurysm, nonruptured	0.842	0.158	0.000
G30-G32 Other degenerative diseases of the nervous system	0.841	0.159	0.000
N30-N39 Other diseases of urinary system	0.841	0.159	0.000
I69 Sequelae of cerebrovascular disease	0.839	0.161	0.000
M46 Other inflammatory spondylopathies	0.838	0.162	0.000
M24 Other specific joint derangements	0.835	0.165	0.000
I60 Subarachnoid haemorrhage	0.833	0.167	0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified	0.832	0.168	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.831	0.169	0.000
G61 Inflammatory polyneuropathy	0.830	0.170	0.000
E88 Other metabolic disorders	0.830	0.170	0.000
K76 Other diseases of liver	0.830	0.170	0.000
Chapter I Certain infectious and parasitic diseases	0.828	0.172	0.000
G90-G99 Other disorders of the nervous system	0.824	0.176	0.000
M86-M90 Other osteopathies	0.824	0.176	0.000
K70 Alcoholic liver disease	0.822	0.178	0.000
L40.8 Other psoriasis	0.821	0.179	0.000
F32 Depressive episode	0.820	0.180	0.000
G45.3 Amaurosis fugax	0.819	0.181	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.814	0.186	0.000
G70-G73 Diseases of myoneural junction and muscle	0.813	0.187	0.000
N20.9 Urinary calculus, unspecified	0.813	0.187	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.812	0.188	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.811	0.189	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.809	0.191	0.000
Y57 Other and unspecified drugs and medicaments	0.808	0.192	0.000
N31.9 Neuromuscular dysfunction of bladder, unspecified	0.805	0.195	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.002	0.197	0.801
T43.4 Butyrophenone and thioxanthene neuroleptics	0.801	0.199	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.801	0.199	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.800	0.200	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.797	0.203	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.795	0.205	0.000
M25.5 Pain in joint	0.792	0.208	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.792	0.208	0.000
G40.9 Epilepsy, unspecified	0.791	0.209	0.000
I25.3 Aneurysm of heart	0.790	0.210	0.000
M70-M79 Other soft tissue disorders	0.789	0.211	0.000
X50-X57 Overexertion, travel and privation	0.787	0.213	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.787	0.213	0.000
E87.2 Acidosis	0.787	0.213	0.000
J42 Unspecified chronic bronchitis	0.000	0.214	0.786
S32.0 Fracture of lumbar vertebra	0.783	0.217	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.781	0.219	0.000
F60-F69 Disorders of adult personality and behaviour	0.781	0.219	0.000
M60-M63 Disorders of muscles	0.779	0.221	0.000
W50-W64 Exposure to animate mechanical forces	0.777	0.223	0.000
I20.8 Other forms of angina pectoris	0.776	0.224	0.000
V10-V19 Pedal cyclist injured in transport accident	0.776	0.224	0.000
E78.2 Mixed hyperlipidaemia	0.776	0.224	0.000
E06 Thyroiditis	0.011	0.228	0.761
S60-S69 Injuries to the wrist and hand	0.771	0.229	0.000
S31 Open wound of abdomen, lower back and pelvis	0.771	0.229	0.000
Y43.0 Antiallergic and antiemetic drugs	0.770	0.230	0.000
E10-E14 Diabetes mellitus	0.768	0.231	0.001
X60-X84 Intentional self-harm	0.765	0.235	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.764	0.236	0.000
K76.8 Other specified diseases of liver	0.764	0.236	0.000
N31.8 Other neuromuscular dysfunction of bladder	0.761	0.239	0.000
E87.1 Hypo-osmolality and hyponatraemia	0.760	0.240	0.000
W44 Foreign body entering into or through eye or natural orifice	0.760	0.240	0.000
N13.8 Other obstructive and reflux uropathy	0.760	0.240	0.000
G24.9 Dystonia, unspecified	0.758	0.242	0.000
T39.0 Salicylates	0.758	0.242	0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.758	0.242	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.755	0.245	0.000
N11 Chronic tubulo-interstitial nephritis	0.755	0.245	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.754	0.245	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.754	0.246	0.000
K86 Other diseases of pancreas	0.754	0.246	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.753	0.247	0.000
G44 Other headache syndromes	0.752	0.247	0.000
M46.9 Inflammatory spondylopathy, unspecified	0.751	0.249	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.751	0.249	0.000
T51 Toxic effect of alcohol	0.751	0.249	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.750	0.250	0.000
N99-N99 Other disorders of the genitourinary system	0.749	0.251	0.000
I67.9 Cerebrovascular disease, unspecified	0.747	0.253	0.000
I61 Intracerebral haemorrhage	0.747	0.253	0.000
G96 Other disorders of central nervous system	0.746	0.254	0.000
D68 Other coagulation defects	0.746	0.254	0.000
K83 Other diseases of biliary tract	0.746	0.254	0.000
S80 Superficial injury of lower leg	0.745	0.255	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.744	0.256	0.000
G60 Hereditary and idiopathic neuropathy	0.744	0.256	0.000
S70-S79 Injuries to the hip and thigh	0.744	0.256	0.000
K72 Hepatic failure, not elsewhere classified	0.743	0.257	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.742	0.258	0.000
V20-V29 Motorcycle rider injured in transport accident	0.739	0.261	0.000
S32.4 Fracture of acetabulum	0.738	0.262	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.737	0.263	0.000
I67.2 Cerebral atherosclerosis	0.735	0.265	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.734	0.266	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.733	0.267	0.000
Y43.1 Antineoplastic antimetabolites	0.732	0.268	0.000
E40-E46 Malnutrition	0.730	0.269	0.001
F11 Mental and behavioural disorders due to use of opioids	0.730	0.270	0.000
D75 Other diseases of blood and blood-forming organs	0.728	0.272	0.000
M00-M03 Infectious arthropathies	0.727	0.272	0.000
K70.1 Alcoholic hepatitis	0.726	0.274	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.726	0.274	0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.725	0.275	0.000
E28 Ovarian dysfunction	0.723	0.277	0.000
M91-M94 Chondropathies	0.723	0.277	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.722	0.278	0.000
B35-B49 Mycoses	0.722	0.278	0.000
D66 Hereditary factor VIII deficiency	0.722	0.278	0.000
M77 Other enthesopathies	0.721	0.279	0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.721	0.279	0.000
T42.4 Benzodiazepines	0.721	0.279	0.000
F32.0 Mild depressive episode	0.718	0.282	0.000
I22 Subsequent myocardial infarction	0.718	0.282	0.000
I25.1 Atherosclerotic heart disease	0.718	0.282	0.000
L40.4 Guttate psoriasis	0.717	0.283	0.000
L40.3 Pustulosis palmaris et plantaris	0.717	0.283	0.000
L40.2 Acrodermatitis continua	0.717	0.283	0.000
L40.1 Generalised pustular psoriasis	0.717	0.283	0.000
T33-T35 Frostbite	0.717	0.283	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283	0.000
T00-T07 Injuries involving multiple body regions	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.717	0.283	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.717	0.283	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.717	0.283	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.717	0.283	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.717	0.283	0.000
T36 Poisoning by systemic antibiotics	0.717	0.283	0.000
I23 Certain current complications following acute myocardial infarction	0.717	0.283	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.717	0.283	0.000
I00-I02 Acute rheumatic fever	0.716	0.284	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.716	0.284	0.000
L44 Other papulosquamous disorders	0.715	0.285	0.000
L41 Parapsoriasis	0.715	0.285	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.715	0.285	0.000
L42 Pityriasis rosea	0.715	0.285	0.000
G46 Vascular syndromes of brain in cerebrovascular diseases	0.714	0.285	0.000
L10-L14 Bullous disorders	0.714	0.286	0.000
M07.38 Other psoriatic arthropathies (Other)	0.714	0.286	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.714	0.286	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.714	0.286	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.714	0.286	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.714	0.286	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.714	0.286	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.714	0.286	0.000
M07.6 Other enteropathic arthropathies	0.714	0.286	0.000
M07.5 Arthropathy in ulcerative colitis	0.714	0.286	0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.714	0.286	0.000
M07.2 Psoriatic spondylitis	0.714	0.286	0.000
M07.1 Arthritis mutilans	0.714	0.286	0.000
M07.0 Distal interphalangeal psoriatic arthropathy	0.714	0.286	0.000
M14 Arthropathies in other diseases classified elsewhere	0.714	0.286	0.000
M12 Other specific arthropathies	0.714	0.286	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.714	0.286	0.000
M08 Juvenile arthritis	0.714	0.286	0.000
F41 Other anxiety disorders	0.713	0.287	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.713	0.287	0.000
T43.9 Psychotropic drug, unspecified	0.713	0.287	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.713	0.287	0.000
T43.6 Psychostimulants with abuse potential	0.713	0.287	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.713	0.287	0.000
G40.8 Other epilepsy	0.713	0.287	0.000
E78.8 Other disorders of lipoprotein metabolism	0.713	0.287	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.712	0.288	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.712	0.288	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.712	0.288	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.711	0.288	0.000
N22 Calculus of urinary tract in diseases classified elsewhere	0.711	0.289	0.000
S32.00 Fracture of lumbar vertebra (closed)	0.711	0.289	0.000
G63 Polyneuropathy in diseases classified elsewhere	0.710	0.290	0.000
Y35-Y36 Legal intervention and operations of war	0.709	0.290	0.000
Y10-Y34 Event of undetermined intent	0.709	0.290	0.000
Y00-Y09 Assault	0.709	0.290	0.000
X85-X99 Assault	0.709	0.290	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.709	0.290	0.000
X30-X39 Exposure to forces of nature	0.709	0.290	0.000
X20-X29 Contact with venomous animals and plants	0.709	0.290	0.000
X10-X19 Contact with heat and hot substances	0.709	0.290	0.000
X00-X09 Exposure to smoke, fire and flames	0.709	0.290	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.709	0.290	0.000
W75-W84 Other accidental threats to breathing	0.709	0.290	0.000
W65-W74 Accidental drowning and submersion	0.709	0.290	0.000
V98-V99 Other and unspecified transport accidents	0.709	0.290	0.000
V95-V97 Air and space transport accidents	0.709	0.290	0.000
V90-V94 Water transport accidents	0.709	0.290	0.000
V70-V79 Bus occupant injured in transport accident	0.709	0.290	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.709	0.290	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.709	0.290	0.000
V40-V49 Car occupant injured in transport accident	0.709	0.290	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.709	0.290	0.000
V01-V09 Pedestrian injured in transport accident	0.709	0.290	0.000
G40.7 Petit mal, unspecified, without grand mal seizures	0.709	0.291	0.000
G40.5 Special epileptic syndromes	0.709	0.291	0.000
G40.4 Other generalised epilepsy and epileptic syndromes	0.709	0.291	0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset	0.709	0.291	0.000
M21 Other acquired deformities of limbs	0.709	0.291	0.000
T17 Foreign body in respiratory tract	0.708	0.292	0.000
I20.9 Angina pectoris, unspecified	0.707	0.293	0.000
G64 Other disorders of peripheral nervous system	0.706	0.294	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.706	0.294	0.000
F70-F79 Mental retardation	0.706	0.294	0.000
I69.0 Sequelae of subarachnoid haemorrhage	0.706	0.294	0.000
E78.4 Other hyperlipidaemia	0.706	0.294	0.000
E85 Amyloidosis	0.704	0.295	0.000
E84 Cystic fibrosis	0.704	0.295	0.000
E79 Disorders of purine and pyrimidine metabolism	0.704	0.295	0.000
E77 Disorders of glycoprotein metabolism	0.704	0.295	0.000
E76 Disorders of glycosaminoglycan metabolism	0.704	0.295	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.704	0.295	0.000
E74 Other disorders of carbohydrate metabolism	0.704	0.295	0.000
E73 Lactose intolerance	0.704	0.295	0.000
E72 Other disorders of amino-acid metabolism	0.704	0.295	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.704	0.295	0.000
E70 Disorders of aromatic amino-acid metabolism	0.704	0.295	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.704	0.295	0.000
I24.1 Dressler's syndrome	0.704	0.296	0.000
G61.8 Other inflammatory polyneuropathies	0.704	0.296	0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.703	0.297	0.000
N15 Other renal tubulo-interstitial diseases	0.703	0.297	0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.703	0.297	0.000
Q50-Q56 Congenital malformations of genital organs	0.703	0.297	0.000
E78.6 Lipoprotein deficiency	0.702	0.298	0.000
E78.3 Hyperchylomicronaemia	0.702	0.298	0.000
E78.1 Pure hyperglyceridaemia	0.702	0.298	0.000
S40-S49 Injuries to the shoulder and upper arm	0.701	0.298	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.701	0.299	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.701	0.299	0.000
E22 Hyperfunction of pituitary gland	0.700	0.300	0.000
D70 Agranulocytosis	0.700	0.300	0.000
F30 Manic episode	0.698	0.301	0.000
M43 Other deforming dorsopathies	0.698	0.302	0.000
S60 Superficial injury of wrist and hand	0.697	0.303	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.697	0.303	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.697	0.303	0.000
N13.7 Vesicoureteral-reflux-associated uropathy	0.697	0.303	0.000
G41 Status epilepticus	0.697	0.303	0.000
S81 Open wound of lower leg	0.697	0.303	0.000
F80-F89 Disorders of psychological development	0.697	0.303	0.000
E26 Hyperaldosteronism	0.696	0.304	0.000
T90 Sequelae of injuries of head	0.696	0.304	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.695	0.305	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.695	0.305	0.000
T39.4 Antirheumatics, not elsewhere classified	0.695	0.305	0.000
T39.2 Pyrazolone derivatives	0.695	0.305	0.000
S90-S99 Injuries to the ankle and foot	0.695	0.305	0.000
E03.8 Other specified hypothyroidism	0.006	0.306	0.688
E03.5 Myxoedema coma	0.006	0.306	0.688
E03.4 Atrophy of thyroid (acquired)	0.006	0.306	0.688
E03.3 Postinfectious hypothyroidism	0.006	0.306	0.688
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.006	0.306	0.688
E03.1 Congenital hypothyroidism without goitre	0.006	0.306	0.688
E03.0 Congenital hypothyroidism with diffuse goitre	0.006	0.306	0.688
G24.3 Spasmodic torticollis	0.694	0.306	0.000
N21 Calculus of lower urinary tract	0.693	0.307	0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.691	0.309	0.000
M47.80 Other spondylosis (Multiple sites in spine)	0.691	0.309	0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.691	0.309	0.000
F18 Mental and behavioural disorders due to use of volatile solvents	0.691	0.309	0.000
F16 Mental and behavioural disorders due to use of hallucinogens	0.691	0.309	0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.691	0.309	0.000
F14 Mental and behavioural disorders due to use of cocaine	0.691	0.309	0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.691	0.309	0.000
F12 Mental and behavioural disorders due to use of cannabinoids	0.691	0.309	0.000
L00-L08 Infections of the skin and subcutaneous tissue	0.691	0.309	0.000
E07 Other disorders of thyroid	0.012	0.310	0.678
M11 Other crystal arthropathies	0.690	0.310	0.000
G62.2 Polyneuropathy due to other toxic agents	0.690	0.310	0.000
G62.1 Alcoholic polyneuropathy	0.690	0.310	0.000
G62.0 Drug-induced polyneuropathy	0.690	0.310	0.000
M41 Scoliosis	0.689	0.311	0.000
W25 Contact with sharp glass	0.688	0.312	0.000
J44 Other chronic obstructive pulmonary disease	0.000	0.312	0.688
Y59 Other and unspecified vaccines and biological substances	0.687	0.313	0.000
Y58 Bacterial vaccines	0.687	0.313	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.687	0.313	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.687	0.313	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.687	0.313	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.687	0.313	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.687	0.313	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.687	0.313	0.000
Y48 Anaesthetics and therapeutic gases	0.687	0.313	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.687	0.313	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.687	0.313	0.000
J45.0 Predominantly allergic asthma	0.000	0.313	0.687
W49 Exposure to other and unspecified inanimate mechanical forces	0.687	0.313	0.000
W46 Contact with hypodermic needle	0.687	0.313	0.000
W45 Foreign body or object entering through skin	0.687	0.313	0.000
W43 Exposure to vibration	0.687	0.313	0.000
W42 Exposure to noise	0.687	0.313	0.000
W41 Exposure to high-pressure jet	0.687	0.313	0.000
W40 Explosion of other materials	0.687	0.313	0.000
W39 Discharge of firework	0.687	0.313	0.000
W38 Explosion and rupture of other specified pressurised devices	0.687	0.313	0.000
W37 Explosion and rupture of pressurised tyre, pipe or hose	0.687	0.313	0.000
W36 Explosion and rupture of gas cylinder	0.687	0.313	0.000
W35 Explosion and rupture of boiler	0.687	0.313	0.000
W34 Discharge from other and unspecified firearms	0.687	0.313	0.000
W33 Rifle, shotgun and larger firearm discharge	0.687	0.313	0.000
W32 Handgun discharge	0.687	0.313	0.000
W31 Contact with other and unspecified machinery	0.687	0.313	0.000
W30 Contact with agricultural machinery	0.687	0.313	0.000
W28 Contact with powered lawn mower	0.687	0.313	0.000
W27 Contact with nonpowered hand tool	0.687	0.313	0.000
W26 Contact with knife, sword or dagger	0.687	0.313	0.000
W24 Contact with lifting and transmission devices, not elsewhere classified	0.687	0.313	0.000
W23 Caught, crushed, jammed or pinched in or between objects	0.687	0.313	0.000
W21 Striking against or struck by sports equipment	0.687	0.313	0.000
W20 Struck by thrown, projected or falling object	0.687	0.313	0.000
G45.8 Other transient cerebral ischaemic attacks and related syndromes	0.686	0.314	0.000
G45.2 Multiple and bilateral precerebral artery syndromes	0.686	0.314	0.000
G45.1 Carotid artery syndrome (hemispheric)	0.686	0.314	0.000
G45.0 Vertebro-basilar artery syndrome	0.686	0.314	0.000
G20 Parkinson's disease	0.686	0.314	0.000
F41.9 Anxiety disorder, unspecified	0.686	0.314	0.000
K86.3 Pseudocyst of pancreas	0.686	0.314	0.000
M25.52 Pain in joint (Upper arm)	0.686	0.314	0.000
F17.9 Unspecified mental and behavioural disorder	0.685	0.315	0.000
F17.8 Other mental and behavioural disorders	0.685	0.315	0.000
F17.7 Residual and late-onset psychotic disorder	0.685	0.315	0.000
F17.6 Amnesic syndrome	0.685	0.315	0.000
F17.5 Psychotic disorder	0.685	0.315	0.000
F17.4 Withdrawal state with delirium	0.685	0.315	0.000
F17.3 Withdrawal state	0.685	0.315	0.000
F17.0 Acute intoxication	0.685	0.315	0.000
T79-T79 Certain early complications of trauma	0.684	0.315	0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.684	0.316	0.000
G96.0 Cerebrospinal fluid leak	0.683	0.317	0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.682	0.317	0.000
S37 Injury of urinary and pelvic organs	0.682	0.317	0.000
S36 Injury of intra-abdominal organs	0.682	0.317	0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.682	0.317	0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.682	0.317	0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.682	0.317	0.000
S14 Injury of nerves and spinal cord at neck level	0.682	0.318	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.682	0.318	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.682	0.318	0.000
T42.3 Barbiturates	0.682	0.318	0.000
T42.2 Succinimides and oxazolidinediones	0.682	0.318	0.000
T42.1 Iminostilbenes	0.682	0.318	0.000
T42.0 Hydantoin derivatives	0.682	0.318	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.681	0.318	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.681	0.318	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.681	0.319	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.013	0.319	0.668
E00 Congenital iodine-deficiency syndrome	0.013	0.319	0.668
E02 Subclinical iodine-deficiency hypothyroidism	0.013	0.319	0.668
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.681	0.319	0.000
I25.6 Silent myocardial ischaemia	0.680	0.320	0.000
I25.4 Coronary artery aneurysm	0.680	0.320	0.000
V80-V89 Other land transport accidents	0.680	0.320	0.000
Y43.9 Primarily systemic agent, unspecified	0.680	0.320	0.000
Y43.8 Other primarily systemic agents, not elsewhere classified	0.680	0.320	0.000
Y43.6 Enzymes, not elsewhere classified	0.680	0.320	0.000
Y43.5 Acidifying and alkalising agents	0.680	0.320	0.000
Y43.2 Antineoplastic natural products	0.680	0.320	0.000
N10 Acute tubulo-interstitial nephritis	0.680	0.320	0.000
M24.1 Other articular cartilage disorders	0.679	0.321	0.000
S10 Superficial injury of neck	0.679	0.321	0.000
D75.1 Secondary polycythaemia	0.679	0.321	0.000
M65-M68 Disorders of synovium and tendon	0.678	0.321	0.000
M24.6 Ankylosis of joint	0.678	0.322	0.000
T91 Sequelae of injuries of neck and trunk	0.678	0.322	0.000
N13.4 Hydroureter	0.677	0.323	0.000
B20-B24 Human immunodeficiency virus [HIV] disease	0.676	0.324	0.000
T98 Sequelae of other and unspecified effects of external causes	0.676	0.324	0.000
S30 Superficial injury of abdomen, lower back and pelvis	0.675	0.325	0.000
E11 Non-insulin-dependent diabetes mellitus	0.675	0.325	0.000
F99-F99 Unspecified mental disorder	0.675	0.325	0.000
S62 Fracture at wrist and hand level	0.674	0.326	0.000
M49 Spondylopathies in diseases classified elsewhere	0.674	0.326	0.000
E23 Hypofunction and other disorders of pituitary gland	0.672	0.328	0.000
Q80-Q89 Other congenital malformations	0.672	0.328	0.000
F32.2 Severe depressive episode without psychotic symptoms	0.672	0.328	0.000
K76.0 Fatty (change of) liver, not elsewhere classified	0.671	0.329	0.000
Y57.8 Other drugs and medicaments	0.671	0.329	0.000
W22.8 Other specified place	0.670	0.330	0.000
W22.6 Industrial and construction area	0.670	0.330	0.000
W22.4 Street and highway	0.670	0.330	0.000
W22.0 Home	0.670	0.330	0.000
W22.7 Farm	0.670	0.330	0.000
W22.5 Trade and service area	0.670	0.330	0.000
W22.3 Sports and athletics area	0.670	0.330	0.000
W22.2 School, other institution and public administrative area	0.670	0.330	0.000
W22.1 Residential institution	0.670	0.330	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.670	0.330	0.000
B65-B83 Helminthiases	0.668	0.331	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.668	0.332	0.000
K70.3 Alcoholic cirrhosis of liver	0.668	0.332	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.668	0.332	0.000
M25.59 Pain in joint (Site unspecified)	0.667	0.333	0.000
S32.1 Fracture of sacrum	0.667	0.333	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations