TreeWAS – Variant ID: rs29255

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
L40.9 Psoriasis, unspecified	1.000	0.000	0.000
L40.5 Arthropathic psoriasis	1.000	0.000	0.000
L40 Psoriasis	1.000	0.000	0.000
E03.9 Hypothyroidism, unspecified	0.000	0.004	0.996
L40-L45 Papulosquamous disorders	0.995	0.005	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.994	0.006	0.000
# Top node	0.994	0.006	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.993	0.007	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.991	0.009	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.991	0.009	0.000
Chapter VI Diseases of the nervous system	0.989	0.011	0.000
M05-M14 Inflammatory polyarthropathies	0.988	0.012	0.000
M07.3 Other psoriatic arthropathies	0.988	0.012	0.000
M07 Psoriatic and enteropathic arthropathies	0.987	0.013	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.978	0.022	0.000
E03 Other hypothyroidism	0.000	0.027	0.973
M86-M90 Other osteopathies	0.965	0.035	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.961	0.039	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.957	0.043	0.000
E00-E07 Disorders of thyroid gland	0.000	0.046	0.954
M07.30 Other psoriatic arthropathies (Multiple sites)	0.952	0.048	0.000
M70-M79 Other soft tissue disorders	0.934	0.066	0.000
G40-G47 Episodic and paroxysmal disorders	0.933	0.067	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.931	0.069	0.000
G40 Epilepsy	0.928	0.072	0.000
L40.0 Psoriasis vulgaris	0.917	0.083	0.000
M89 Other disorders of bone	0.912	0.088	0.000
K90.0 Coeliac disease	0.000	0.088	0.912
T43.2 Other and unspecified antidepressants	0.911	0.089	0.000
G35 Multiple sclerosis	0.909	0.091	0.000
Chapter II Neoplasms	0.906	0.094	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.094	0.906
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.905	0.095	0.000
M60-M63 Disorders of muscles	0.902	0.098	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.902	0.098	0.000
Chapter V Mental and behavioural disorders	0.894	0.106	0.000
G40.9 Epilepsy, unspecified	0.882	0.118	0.000
G20-G26 Extrapyramidal and movement disorders	0.878	0.122	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.875	0.125	0.000
M89.9 Disorder of bone, unspecified	0.873	0.127	0.000
Chapter XIV Diseases of the genitourinary system	0.870	0.130	0.000
E05.9 Thyrotoxicosis, unspecified	0.000	0.131	0.869
D00-D09 In situ neoplasms	0.868	0.132	0.000
M77 Other enthesopathies	0.867	0.133	0.000
G70-G73 Diseases of myoneural junction and muscle	0.864	0.135	0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.860	0.140	0.000
T18 Foreign body in alimentary tract	0.856	0.144	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.854	0.145	0.000
G37 Other demyelinating diseases of central nervous system	0.854	0.146	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.853	0.147	0.000
N60-N64 Disorders of breast	0.852	0.148	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.849	0.151	0.000
S40-S49 Injuries to the shoulder and upper arm	0.848	0.152	0.000
F30-F39 Mood [affective] disorders	0.848	0.152	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.847	0.153	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	0.847	0.153	0.000
M10 Gout	0.845	0.155	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.844	0.156	0.000
L57 Skin changes due to chronic exposure to nonionising radiation	0.843	0.157	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.003	0.158	0.839
M62 Other disorders of muscle	0.835	0.165	0.000
N20-N23 Urolithiasis	0.834	0.166	0.000
M45-M49 Spondylopathies	0.834	0.166	0.000
N63 Unspecified lump in breast	0.833	0.167	0.000
C44 Other malignant neoplasms of skin	0.830	0.170	0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.830	0.170	0.000
E10 Insulin-dependent diabetes mellitus	0.000	0.175	0.825
E10-E14 Diabetes mellitus	0.001	0.175	0.824
E10.9 Without complications	0.000	0.180	0.820
M07.36 Other psoriatic arthropathies (Lower leg)	0.820	0.180	0.000
M87 Osteonecrosis	0.818	0.182	0.000
G30-G32 Other degenerative diseases of the nervous system	0.817	0.183	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.816	0.184	0.000
N10-N16 Renal tubulo-interstitial diseases	0.812	0.188	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.811	0.189	0.000
T39.1 4-Aminophenol derivatives	0.809	0.191	0.000
N20 Calculus of kidney and ureter	0.805	0.195	0.000
S90-S99 Injuries to the ankle and foot	0.805	0.195	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.804	0.196	0.000
M00-M03 Infectious arthropathies	0.802	0.197	0.000
L57.0 Actinic keratosis	0.802	0.198	0.000
S10-S19 Injuries to the neck	0.802	0.198	0.000
T36 Poisoning by systemic antibiotics	0.801	0.199	0.000
E06 Thyroiditis	0.000	0.200	0.800
M79 Other soft tissue disorders, not elsewhere classified	0.798	0.202	0.000
N13 Obstructive and reflux uropathy	0.797	0.203	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.794	0.206	0.000
M91-M94 Chondropathies	0.794	0.206	0.000
S60-S69 Injuries to the wrist and hand	0.789	0.211	0.000
G70 Myasthenia gravis and other myoneural disorders	0.789	0.211	0.000
M62.8 Other specified disorders of muscle	0.787	0.213	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.787	0.213	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.214	0.786
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.785	0.215	0.000
N64 Other disorders of breast	0.785	0.215	0.000
F31 Bipolar affective disorder	0.780	0.220	0.000
M71 Other bursopathies	0.778	0.222	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.778	0.222	0.000
M89.94 Disorder of bone, unspecified (Hand)	0.776	0.224	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.776	0.224	0.000
N20.1 Calculus of ureter	0.774	0.226	0.000
L40.8 Other psoriasis	0.769	0.231	0.000
M46 Other inflammatory spondylopathies	0.767	0.233	0.000
T17 Foreign body in respiratory tract	0.766	0.234	0.000
D04 Carcinoma in situ of skin	0.763	0.237	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.763	0.237	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.758	0.242	0.000
M50-M54 Other dorsopathies	0.758	0.242	0.000
T18.1 Foreign body in oesophagus	0.755	0.245	0.000
D05 Carcinoma in situ of breast	0.755	0.245	0.000
S32 Fracture of lumbar spine and pelvis	0.754	0.246	0.000
F30 Manic episode	0.754	0.246	0.000
M90 Osteopathies in diseases classified elsewhere	0.753	0.247	0.000
C15-C26 Malignant neoplasms of digestive organs	0.753	0.247	0.000
G62 Other polyneuropathies	0.753	0.247	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.751	0.249	0.000
G24 Dystonia	0.748	0.252	0.000
C02 Malignant neoplasm of other and unspecified parts of tongue	0.747	0.253	0.000
D07 Carcinoma in situ of other and unspecified genital organs	0.747	0.253	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.746	0.254	0.000
M10.9 Gout, unspecified	0.743	0.257	0.000
G41 Status epilepticus	0.743	0.257	0.000
S31 Open wound of abdomen, lower back and pelvis	0.743	0.257	0.000
S62 Fracture at wrist and hand level	0.743	0.257	0.000
N64.5 Other signs and symptoms in breast	0.739	0.261	0.000
G40.7 Petit mal, unspecified, without grand mal seizures	0.737	0.262	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.737	0.263	0.000
N61 Inflammatory disorders of breast	0.737	0.263	0.000
G70.0 Myasthenia gravis	0.734	0.266	0.000
T45.0 Antiallergic and antiemetic drugs	0.734	0.266	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.733	0.267	0.000
E03.8 Other specified hypothyroidism	0.000	0.267	0.733
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.731	0.269	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.731	0.269	0.000
S92 Fracture of foot, except ankle	0.730	0.270	0.000
M77.1 Lateral epicondylitis	0.729	0.271	0.000
T18.9 Foreign body in alimentary tract, part unspecified	0.729	0.271	0.000
M79.0 Rheumatism, unspecified	0.729	0.271	0.000
M50 Cervical disk disorders	0.724	0.276	0.000
E10.3 With ophthalmic complications	0.000	0.280	0.720
C44.7 Skin of lower limb, including hip	0.718	0.282	0.000
L40.4 Guttate psoriasis	0.717	0.283	0.000
L40.3 Pustulosis palmaris et plantaris	0.717	0.283	0.000
L40.2 Acrodermatitis continua	0.717	0.283	0.000
L40.1 Generalised pustular psoriasis	0.717	0.283	0.000
N20.0 Calculus of kidney	0.716	0.284	0.000
M79.1 Myalgia	0.715	0.285	0.000
L44 Other papulosquamous disorders	0.713	0.287	0.000
L41 Parapsoriasis	0.713	0.287	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.713	0.287	0.000
L42 Pityriasis rosea	0.713	0.287	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.712	0.287	0.000
L10-L14 Bullous disorders	0.712	0.288	0.000
T33-T35 Frostbite	0.711	0.289	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.711	0.289	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.710	0.290	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.710	0.290	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.710	0.290	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.710	0.290	0.000
M50.3 Other cervical disk degeneration	0.709	0.291	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.709	0.291	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.709	0.291	0.000
M89.3 Hypertrophy of bone	0.708	0.291	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.708	0.292	0.000
M12 Other specific arthropathies	0.708	0.292	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.708	0.292	0.000
M08 Juvenile arthritis	0.708	0.292	0.000
M07.38 Other psoriatic arthropathies (Other)	0.708	0.292	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.708	0.292	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.708	0.292	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.708	0.292	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.708	0.292	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.708	0.292	0.000
M07.6 Other enteropathic arthropathies	0.708	0.292	0.000
M07.5 Arthropathy in ulcerative colitis	0.708	0.292	0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.708	0.292	0.000
M07.2 Psoriatic spondylitis	0.708	0.292	0.000
M07.1 Arthritis mutilans	0.708	0.292	0.000
M07.0 Distal interphalangeal psoriatic arthropathy	0.708	0.292	0.000
M77.0 Medial epicondylitis	0.708	0.292	0.000
M72 Fibroblastic disorders	0.707	0.293	0.000
C44.5 Skin of trunk	0.706	0.294	0.000
C44.0 Skin of lip	0.705	0.295	0.000
M86 Osteomyelitis	0.704	0.296	0.000
G20 Parkinson's disease	0.704	0.296	0.000
T00-T07 Injuries involving multiple body regions	0.704	0.296	0.000
C44.3 Skin of other and unspecified parts of face	0.704	0.296	0.000
M70 Soft tissue disorders related to use, overuse and pressure	0.704	0.296	0.000
C44.2 Skin of ear and external auricular canal	0.704	0.296	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.701	0.299	0.000
M46.9 Inflammatory spondylopathy, unspecified	0.700	0.300	0.000
C18 Malignant neoplasm of colon	0.699	0.301	0.000
M77.9 Enthesopathy, unspecified	0.698	0.301	0.000
C06 Malignant neoplasm of other and unspecified parts of mouth	0.698	0.302	0.000
E03.5 Myxoedema coma	0.000	0.302	0.697
E03.4 Atrophy of thyroid (acquired)	0.000	0.302	0.697
E03.3 Postinfectious hypothyroidism	0.000	0.302	0.697
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.302	0.697
E03.1 Congenital hypothyroidism without goitre	0.000	0.302	0.697
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.302	0.697
M76 Enthesopathies of lower limb, excluding foot	0.697	0.303	0.000
T39.0 Salicylates	0.694	0.306	0.000
E06.3 Autoimmune thyroiditis	0.000	0.306	0.694
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.693	0.306	0.000
C44.4 Skin of scalp and neck	0.692	0.308	0.000
Chapter XXII Codes for special purposes	0.690	0.310	0.000
M80-M85 Disorders of bone density and structure	0.690	0.310	0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.690	0.310	0.000
Chapter I Certain infectious and parasitic diseases	0.689	0.311	0.000
M87.9 Osteonecrosis, unspecified	0.689	0.311	0.000
S37 Injury of urinary and pelvic organs	0.689	0.311	0.000
M14 Arthropathies in other diseases classified elsewhere	0.689	0.311	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.689	0.311	0.000
G36 Other acute disseminated demyelination	0.689	0.311	0.000
N13.3 Other and unspecified hydronephrosis	0.688	0.312	0.000
M88 Paget's disease of bone [osteitis deformans]	0.687	0.313	0.000
S62.3 Fracture of other metacarpal bone	0.687	0.313	0.000
F80-F89 Disorders of psychological development	0.686	0.314	0.000
T43.9 Psychotropic drug, unspecified	0.686	0.314	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.686	0.314	0.000
T43.6 Psychostimulants with abuse potential	0.686	0.314	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.686	0.314	0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.686	0.314	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.316	0.684
E00 Congenital iodine-deficiency syndrome	0.000	0.316	0.684
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.316	0.684
T16 Foreign body in ear	0.683	0.317	0.000
N21 Calculus of lower urinary tract	0.683	0.317	0.000
E20-E35 Disorders of other endocrine glands	0.001	0.318	0.682
T47.1 Other antacids and anti-gastric-secretion drugs	0.682	0.318	0.000
M89.5 Osteolysis	0.681	0.319	0.000
L60-L75 Disorders of skin appendages	0.680	0.320	0.000
M62.88 Other specified disorders of muscle (Other)	0.680	0.320	0.000
M77.4 Metatarsalgia	0.677	0.323	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.676	0.324	0.000
M47 Spondylosis	0.676	0.324	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.674	0.326	0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.673	0.327	0.000
S00-S09 Injuries to the head	0.673	0.327	0.000
F39 Unspecified mood [affective] disorder	0.673	0.327	0.000
E07 Other disorders of thyroid	0.000	0.327	0.673
C12 Malignant neoplasm of pyriform sinus	0.672	0.327	0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures	0.672	0.328	0.000
D05.9 Carcinoma in situ of breast, unspecified	0.672	0.328	0.000
S41 Open wound of shoulder and upper arm	0.671	0.329	0.000
N13.6 Pyonephrosis	0.671	0.329	0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)	0.670	0.329	0.000
M73 Soft tissue disorders in diseases classified elsewhere	0.670	0.330	0.000
N13.4 Hydroureter	0.669	0.331	0.000
G46 Vascular syndromes of brain in cerebrovascular diseases	0.669	0.331	0.000
M10.99 Gout, unspecified (Site unspecified)	0.669	0.331	0.000
T19 Foreign body in genito-urinary tract	0.667	0.333	0.000
T15 Foreign body on external eye	0.667	0.333	0.000
D04.4 Skin of scalp and neck	0.666	0.334	0.000
C10 Malignant neoplasm of oropharynx	0.666	0.334	0.000
G40.4 Other generalised epilepsy and epileptic syndromes	0.665	0.334	0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset	0.665	0.334	0.000
T36.0 Penicillins	0.665	0.335	0.000
M00 Pyogenic arthritis	0.665	0.335	0.000
F60-F69 Disorders of adult personality and behaviour	0.664	0.336	0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.663	0.337	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.663	0.337	0.000
G25 Other extrapyramidal and movement disorders	0.663	0.337	0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.661	0.339	0.000
F99-F99 Unspecified mental disorder	0.660	0.340	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.658	0.341	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.658	0.342	0.000
C64-C68 Malignant neoplasms of urinary tract	0.657	0.343	0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.657	0.343	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.655	0.345	0.000
M89.6 Osteopathy after poliomyelitis	0.654	0.346	0.000
M89.4 Other hypertrophic osteo-arthropathy	0.654	0.346	0.000
M89.2 Other disorders of bone development and growth	0.654	0.346	0.000
M89.1 Epiphyseal arrest	0.654	0.346	0.000
M89.0 Algoneurodystrophy	0.654	0.346	0.000
S46 Injury of muscle and tendon at shoulder and upper arm level	0.654	0.346	0.000
M40-M43 Deforming dorsopathies	0.654	0.346	0.000
S49 Other and unspecified injuries of shoulder and upper arm	0.653	0.347	0.000
S10 Superficial injury of neck	0.653	0.347	0.000
T46.1 Calcium-channel blockers	0.652	0.347	0.000
M47.8 Other spondylosis	0.652	0.348	0.000
M62.82 Other specified disorders of muscle (Upper arm)	0.650	0.350	0.000
C02.9 Tongue, unspecified	0.650	0.350	0.000
G62.0 Drug-induced polyneuropathy	0.650	0.350	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.650	0.350	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.650	0.350	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.650	0.350	0.000
E05.8 Other thyrotoxicosis	0.000	0.350	0.649
E05.5 Thyroid crisis or storm	0.000	0.350	0.649
E05.4 Thyrotoxicosis factitia	0.000	0.350	0.649
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.350	0.649
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.350	0.649
Q78 Other osteochondrodysplasias	0.649	0.351	0.000
L59 Other disorders of skin and subcutaneous tissue related to radiation	0.649	0.351	0.000
L58 Radiodermatitis	0.649	0.351	0.000
L56 Other acute skin changes due to ultraviolet radiation	0.649	0.351	0.000
L55 Sunburn	0.649	0.351	0.000
M62.85 Other specified disorders of muscle (Pelvic region and thigh)	0.649	0.351	0.000
Q00-Q07 Congenital malformations of the nervous system	0.649	0.351	0.000
C09 Malignant neoplasm of tonsil	0.649	0.351	0.000
E04 Other non-toxic goitre	0.000	0.352	0.648
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.648	0.352	0.000
M94 Other disorders of cartilage	0.648	0.352	0.000
S30 Superficial injury of abdomen, lower back and pelvis	0.647	0.352	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.647	0.353	0.000
D03 Melanoma in situ	0.647	0.353	0.000
M63 Disorders of muscle in diseases classified elsewhere	0.646	0.354	0.000
M61 Calcification and ossification of muscle	0.646	0.354	0.000
M60 Myositis	0.646	0.354	0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.646	0.354	0.000
S36 Injury of intra-abdominal organs	0.646	0.354	0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.646	0.354	0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.646	0.354	0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.646	0.354	0.000
M79.2 Neuralgia and neuritis, unspecified	0.646	0.354	0.000
F30.2 Mania with psychotic symptoms	0.645	0.355	0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.644	0.356	0.000
L50-L54 Urticaria and erythema	0.644	0.356	0.000
F30.9 Manic episode, unspecified	0.644	0.356	0.000
M71.2 Synovial cyst of popliteal space [Baker]	0.643	0.357	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.641	0.359	0.000
F70-F79 Mental retardation	0.641	0.359	0.000
E27 Other disorders of adrenal gland	0.000	0.361	0.639
T50.9 Other and unspecified drugs, medicaments and biological substances	0.638	0.362	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.638	0.362	0.000
G40.5 Special epileptic syndromes	0.638	0.362	0.000
G31.9 Degenerative disease of nervous system, unspecified	0.637	0.363	0.000
N20.9 Urinary calculus, unspecified	0.636	0.364	0.000
C05 Malignant neoplasm of palate	0.635	0.365	0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.635	0.365	0.000
T17.2 Foreign body in pharynx	0.635	0.365	0.000
T79-T79 Certain early complications of trauma	0.635	0.365	0.000
S62.30 Fracture of other metacarpal bone (closed)	0.634	0.366	0.000
S43.0 Dislocation of shoulder joint	0.631	0.369	0.000
M77.12 Lateral epicondylitis (Upper arm)	0.630	0.369	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.630	0.370	0.000
G23 Other degenerative diseases of basal ganglia	0.630	0.370	0.000
G21 Secondary Parkinsonism	0.630	0.370	0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.630	0.370	0.000
G22 Parkinsonism in diseases classified elsewhere	0.630	0.370	0.000
N13.9 Obstructive and reflux uropathy, unspecified	0.629	0.371	0.000
M79.00 Rheumatism, unspecified (Multiple sites)	0.629	0.371	0.000
N11 Chronic tubulo-interstitial nephritis	0.628	0.372	0.000
N64.8 Other specified disorders of breast	0.628	0.372	0.000
M87.2 Osteonecrosis due to previous trauma	0.628	0.372	0.000
E10.2 With renal complications	0.000	0.372	0.628
M79.7 Fibromyalgia	0.628	0.372	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.627	0.372	0.000
T39.4 Antirheumatics, not elsewhere classified	0.627	0.372	0.000
T39.2 Pyrazolone derivatives	0.627	0.372	0.000
M79.09 Rheumatism, unspecified (Site unspecified)	0.627	0.373	0.000
M11 Other crystal arthropathies	0.627	0.373	0.000
S60 Superficial injury of wrist and hand	0.627	0.373	0.000
M89.99 Disorder of bone, unspecified (Site unspecified)	0.626	0.374	0.000
M89.98 Disorder of bone, unspecified (Other)	0.626	0.374	0.000
M89.96 Disorder of bone, unspecified (Lower leg)	0.626	0.374	0.000
M89.93 Disorder of bone, unspecified (Forearm)	0.626	0.374	0.000
M89.92 Disorder of bone, unspecified (Upper arm)	0.626	0.374	0.000
M89.91 Disorder of bone, unspecified (Shoulder region)	0.626	0.374	0.000
M89.90 Disorder of bone, unspecified (Multiple sites)	0.626	0.374	0.000
C17 Malignant neoplasm of small intestine	0.626	0.374	0.000
M53 Other dorsopathies, not elsewhere classified	0.626	0.374	0.000
S19 Other and unspecified injuries of neck	0.625	0.375	0.000
Q76 Congenital malformations of spine and bony thorax	0.622	0.378	0.000
D02 Carcinoma in situ of middle ear and respiratory system	0.622	0.378	0.000
D01 Carcinoma in situ of other and unspecified digestive organs	0.622	0.378	0.000
M77.8 Other enthesopathies, not elsewhere classified	0.622	0.378	0.000
M77.5 Other enthesopathy of foot	0.622	0.378	0.000
M77.3 Calcaneal spur	0.622	0.378	0.000
M77.2 Periarthritis of wrist	0.622	0.378	0.000
E10.4 With neurological complications	0.000	0.378	0.622
S31.4 Open wound of vagina and vulva	0.621	0.379	0.000
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere	0.620	0.380	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.619	0.381	0.000
M72.2 Plantar fascial fibromatosis	0.619	0.381	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.618	0.382	0.000
E10.1 With ketoacidosis	0.000	0.383	0.617
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.617	0.383	0.000
S02 Fracture of skull and facial bones	0.617	0.383	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.617	0.383	0.000
G24.9 Dystonia, unspecified	0.617	0.383	0.000
F23 Acute and transient psychotic disorders	0.617	0.383	0.000
G40.8 Other epilepsy	0.616	0.384	0.000
S92.1 Fracture of talus	0.615	0.385	0.000
T18.8 Foreign body in other and multiple parts of alimentary tract	0.614	0.386	0.000
T18.5 Foreign body in anus and rectum	0.614	0.386	0.000
T18.4 Foreign body in colon	0.614	0.386	0.000
T18.3 Foreign body in small intestine	0.614	0.386	0.000
T18.2 Foreign body in stomach	0.614	0.386	0.000
T18.0 Foreign body in mouth	0.614	0.386	0.000
G63 Polyneuropathy in diseases classified elsewhere	0.614	0.386	0.000
D07.5 Prostate	0.613	0.387	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.613	0.387	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.613	0.387	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.613	0.387	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.613	0.387	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.613	0.387	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.613	0.387	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.613	0.387	0.000
T44.0 Anticholinesterase agents	0.613	0.387	0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.613	0.387	0.000
G37.8 Other specified demyelinating diseases of central nervous system	0.613	0.387	0.000
G37.5 Concentric sclerosis [Balo]	0.613	0.387	0.000
G37.4 Subacute necrotising myelitis	0.613	0.387	0.000
G37.2 Central pontine myelinolysis	0.613	0.387	0.000
G37.1 Central demyelination of corpus callosum	0.613	0.387	0.000
G37.0 Diffuse sclerosis	0.613	0.387	0.000
C44.9 Malignant neoplasm of skin, unspecified	0.612	0.388	0.000
S32.0 Fracture of lumbar vertebra	0.612	0.388	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.612	0.388	0.000
T45.8 Other primarily systemic and haematological agents	0.612	0.388	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.612	0.388	0.000
T45.6 Fibrinolysis-affecting drugs	0.612	0.388	0.000
T45.5 Anticoagulants	0.612	0.388	0.000
T45.4 Iron and its compounds	0.612	0.388	0.000
T45.3 Enzymes, not elsewhere classified	0.612	0.388	0.000
T45.2 Vitamins, not elsewhere classified	0.612	0.388	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.612	0.388	0.000
C02.4 Lingual tonsil	0.611	0.389	0.000
G62.9 Polyneuropathy, unspecified	0.610	0.389	0.000
C04 Malignant neoplasm of floor of mouth	0.610	0.390	0.000
M79.11 Myalgia (Shoulder region)	0.610	0.390	0.000
M46.4 Discitis, unspecified	0.610	0.390	0.000
D07.1 Vulva	0.609	0.391	0.000
E40-E46 Malnutrition	0.002	0.391	0.607
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.609	0.391	0.000
C13 Malignant neoplasm of hypopharynx	0.609	0.391	0.000
C11 Malignant neoplasm of nasopharynx	0.609	0.391	0.000
C08 Malignant neoplasm of other and unspecified major salivary glands	0.609	0.391	0.000
C03 Malignant neoplasm of gum	0.609	0.391	0.000
C00 Malignant neoplasm of lip	0.609	0.391	0.000
S67 Crushing injury of wrist and hand	0.608	0.392	0.000
S48 Traumatic amputation of shoulder and upper arm	0.608	0.392	0.000
S45 Injury of blood vessels at shoulder and upper arm level	0.608	0.392	0.000
S44 Injury of nerves at shoulder and upper arm level	0.608	0.392	0.000
S47 Crushing injury of shoulder and upper arm	0.608	0.392	0.000
F38 Other mood [affective] disorders	0.608	0.392	0.000
F34 Persistent mood [affective] disorders	0.608	0.392	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.607	0.392	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.607	0.392	0.000
T46.7 Peripheral vasodilators	0.607	0.392	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.607	0.392	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.607	0.392	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.607	0.392	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.607	0.392	0.000
T17.8 Foreign body in other and multiple parts of respiratory tract	0.607	0.393	0.000
N13.5 Kinking and stricture of ureter without hydronephrosis	0.607	0.393	0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.607	0.393	0.000
G41.9 Status epilepticus, unspecified	0.606	0.393	0.000
M10.4 Other secondary gout	0.606	0.394	0.000
M10.3 Gout due to impairment of renal function	0.606	0.394	0.000
M10.2 Drug-induced gout	0.606	0.394	0.000
M10.1 Lead-induced gout	0.606	0.394	0.000
M10.0 Idiopathic gout	0.606	0.394	0.000
M62.86 Other specified disorders of muscle (Lower leg)	0.605	0.395	0.000
G64 Other disorders of peripheral nervous system	0.605	0.395	0.000
M62.81 Other specified disorders of muscle (Shoulder region)	0.605	0.395	0.000
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified	0.604	0.396	0.000
L57.5 Actinic granuloma	0.604	0.396	0.000
L57.4 Cutis laxa senilis	0.604	0.396	0.000
L57.3 Poikiloderma of Civatte	0.604	0.396	0.000
L57.2 Cutis rhomboidalis nuchae	0.604	0.396	0.000
L57.1 Actinic reticuloid	0.604	0.396	0.000
C34 Malignant neoplasm of bronchus and lung	0.604	0.396	0.000
S65 Injury of blood vessels at wrist and hand level	0.604	0.396	0.000
G71 Primary disorders of muscles	0.603	0.397	0.000
M79.4 Hypertrophy of (infrapatellar) fat pad	0.603	0.397	0.000
D05.1 Intraductal carcinoma in situ	0.602	0.398	0.000
M90.7 Fracture of bone in neoplastic disease	0.602	0.398	0.000
D04.6 Skin of upper limb, including shoulder	0.600	0.400	0.000
D06 Carcinoma in situ of cervix uteri	0.599	0.401	0.000
S11 Open wound of neck	0.599	0.401	0.000
S62.6 Fracture of other finger	0.599	0.401	0.000
M62.9 Disorder of muscle, unspecified	0.599	0.401	0.000
M62.6 Muscle strain	0.599	0.401	0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified	0.599	0.401	0.000
M62.4 Contracture of muscle	0.599	0.401	0.000
M62.3 Immobility syndrome (paraplegic)	0.599	0.401	0.000
M62.2 Ischaemic infarction of muscle	0.599	0.401	0.000
M62.1 Other rupture of muscle (nontraumatic)	0.599	0.401	0.000
M62.0 Diastasis of muscle	0.599	0.401	0.000
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)	0.599	0.401	0.000
M05 Seropositive rheumatoid arthritis	0.598	0.401	0.000
E10.5 With peripheral circulatory complications	0.000	0.402	0.598
N25-N29 Other disorders of kidney and ureter	0.598	0.402	0.000
N22 Calculus of urinary tract in diseases classified elsewhere	0.598	0.402	0.000
Q80-Q89 Other congenital malformations	0.598	0.402	0.000
M47.89 Other spondylosis (Site unspecified)	0.597	0.403	0.000
C18.0 Caecum	0.597	0.403	0.000
G24.5 Blepharospasm	0.597	0.403	0.000
G72 Other myopathies	0.596	0.404	0.000
C18.6 Descending colon	0.596	0.404	0.000
M71.3 Other bursal cyst	0.596	0.404	0.000
C44.8 Overlapping lesion of skin	0.595	0.404	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.595	0.405	0.000
S32.4 Fracture of acetabulum	0.594	0.406	0.000
M49 Spondylopathies in diseases classified elsewhere	0.594	0.406	0.000
M77.02 Medial epicondylitis (Upper arm)	0.594	0.406	0.000
E27.1 Primary adrenocortical insufficiency	0.000	0.408	0.592
E10.8 With unspecified complications	0.000	0.408	0.591

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations