TreeWAS
Search
Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
About
Frequently Asked Questions
Citation
Download association data
for this variant in csv format
Share this page

Variant-specific associations

rs2943641
log Bayes Factor = 18.0526
Chromosome 2   position 227,093,745  (GRCh37) Explore rs2943641 on Ensembl!
Variant rs2943641 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
Hierarchical visualisation How to interpret this figure?
Associations at terminal nodes are shown if p(effect) ≥
Click here to show this figure without filtering.
Click on a node to zoom (except terminal nodes).
Download this figure in format
Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E11.9 Without complications
0.000 0.000 1.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.001 0.999
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.002 0.998
I25.1 Atherosclerotic heart disease
0.000 0.011 0.989
I25.5 Ischaemic cardiomyopathy
0.000 0.039 0.961
E78.0 Pure hypercholesterolaemia
0.000 0.103 0.897
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.104 0.896
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.132 0.868
E78.5 Hyperlipidaemia, unspecified
0.000 0.135 0.865
I25.2 Old myocardial infarction
0.000 0.136 0.864
E11 Non-insulin-dependent diabetes mellitus
0.000 0.152 0.848
I20-I25 Ischaemic heart diseases
0.000 0.168 0.832
I20.9 Angina pectoris, unspecified
0.000 0.174 0.826
I20 Angina pectoris
0.000 0.175 0.825
E78.2 Mixed hyperlipidaemia
0.000 0.178 0.822
E11.3 With ophthalmic complications
0.000 0.180 0.820
E78.4 Other hyperlipidaemia
0.000 0.200 0.800
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.225 0.775
E78.1 Pure hyperglyceridaemia
0.000 0.230 0.770
E78.8 Other disorders of lipoprotein metabolism
0.000 0.253 0.747
I25.3 Aneurysm of heart
0.000 0.253 0.747
E10-E14 Diabetes mellitus
0.000 0.280 0.720
I25.6 Silent myocardial ischaemia
0.000 0.293 0.707
E10 Insulin-dependent diabetes mellitus
0.000 0.310 0.690
I20.0 Unstable angina
0.000 0.326 0.674
E10.1 With ketoacidosis
0.000 0.332 0.668
I22 Subsequent myocardial infarction
0.000 0.358 0.642
E11.8 With unspecified complications
0.000 0.361 0.639
E11.4 With neurological complications
0.000 0.377 0.623
E11.7 With multiple complications
0.000 0.392 0.608
E13 Other specified diabetes mellitus
0.000 0.399 0.601
E10.5 With peripheral circulatory complications
0.000 0.409 0.591
E78.3 Hyperchylomicronaemia
0.000 0.410 0.590
E10.8 With unspecified complications
0.000 0.441 0.559
E11.6 With other specified complications
0.000 0.450 0.550
E10.0 With coma
0.000 0.457 0.543
E11.0 With coma
0.000 0.459 0.541
E13.9 Without complications
0.000 0.464 0.536
E10.9 Without complications
0.000 0.483 0.517
E78.6 Lipoprotein deficiency
0.000 0.484 0.516
E12 Malnutrition-related diabetes mellitus
0.000 0.484 0.516
E10.7 With multiple complications
0.000 0.505 0.495
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.520 0.480
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.522 0.478
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.529 0.471
E11.1 With ketoacidosis
0.000 0.529 0.471
I22.8 Subsequent myocardial infarction of other sites
0.000 0.536 0.464
E10.6 With other specified complications
0.000 0.553 0.447
I23 Certain current complications following acute myocardial infarction
0.000 0.556 0.444
E13.8 With unspecified complications
0.000 0.569 0.431
E13.7 With multiple complications
0.000 0.569 0.431
E13.6 With other specified complications
0.000 0.569 0.431
E13.5 With peripheral circulatory complications
0.000 0.569 0.431
E13.4 With neurological complications
0.000 0.569 0.431
E13.2 With renal complications
0.000 0.569 0.431
E13.1 With ketoacidosis
0.000 0.569 0.431
E13.0 With coma
0.000 0.569 0.431
E10.3 With ophthalmic complications
0.000 0.585 0.415
E11.2 With renal complications
0.000 0.593 0.407
I25.4 Coronary artery aneurysm
0.001 0.600 0.400
E10.2 With renal complications
0.000 0.606 0.394
E11.5 With peripheral circulatory complications
0.000 0.619 0.381
E10.4 With neurological complications
0.000 0.623 0.377
E13.3 With ophthalmic complications
0.000 0.623 0.377
I20.1 Angina pectoris with documented spasm
0.000 0.625 0.375
E12.9 Without complications
0.000 0.630 0.370
E12.8 With unspecified complications
0.000 0.630 0.370
E12.7 With multiple complications
0.000 0.630 0.370
E12.6 With other specified complications
0.000 0.630 0.370
E12.5 With peripheral circulatory complications
0.000 0.630 0.370
E12.4 With neurological complications
0.000 0.630 0.370
E12.3 With ophthalmic complications
0.000 0.630 0.370
E12.2 With renal complications
0.000 0.630 0.370
E12.1 With ketoacidosis
0.000 0.630 0.370
E12.0 With coma
0.000 0.630 0.370
I24 Other acute ischaemic heart diseases
0.000 0.631 0.369
I60 Subarachnoid haemorrhage
0.000 0.661 0.339
I60.9 Subarachnoid haemorrhage, unspecified
0.000 0.667 0.333
E14 Unspecified diabetes mellitus
0.000 0.670 0.329
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.681 0.318
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.681 0.318
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.681 0.318
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.681 0.318
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.681 0.318
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.681 0.318
I60-I69 Cerebrovascular diseases
0.000 0.687 0.313
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.000 0.693 0.307
Chapter IX Diseases of the circulatory system
0.000 0.698 0.302
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.000 0.699 0.301
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.000 0.701 0.299
I20.8 Other forms of angina pectoris
0.000 0.705 0.295
I24.1 Dressler's syndrome
0.000 0.709 0.291
I67 Other cerebrovascular diseases
0.000 0.713 0.287
I67.1 Cerebral aneurysm, nonruptured
0.000 0.715 0.285
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.001 0.722 0.277
I62 Other nontraumatic intracranial haemorrhage
0.000 0.728 0.272
I61 Intracerebral haemorrhage
0.000 0.730 0.270
I21 Acute myocardial infarction
0.000 0.732 0.268
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.000 0.732 0.267
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.000 0.739 0.261
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.000 0.745 0.255
I24.8 Other forms of acute ischaemic heart disease
0.000 0.747 0.253
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.000 0.747 0.253
I60.8 Other subarachnoid haemorrhage
0.000 0.752 0.248
I10-I15 Hypertensive diseases
0.000 0.754 0.246
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.754 0.246
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.000 0.754 0.246
E14.9 Without complications
0.000 0.755 0.245
I60.5 Subarachnoid haemorrhage from vertebral artery
0.000 0.756 0.243
I67.2 Cerebral atherosclerosis
0.000 0.759 0.241
I10 Essential (primary) hypertension
0.000 0.760 0.240
E14.4 With neurological complications
0.000 0.761 0.239
I61.9 Intracerebral haemorrhage, unspecified
0.000 0.763 0.237
E14.7 With multiple complications
0.000 0.764 0.236
E14.5 With peripheral circulatory complications
0.000 0.764 0.236
E14.0 With coma
0.000 0.764 0.236
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.764 0.236
I05-I09 Chronic rheumatic heart diseases
0.000 0.765 0.235
I23.8 Other current complications following acute myocardial infarction
0.001 0.766 0.233
E14.2 Withrenal complications
0.000 0.767 0.233
E14.8 With unspecified complications
0.000 0.767 0.233
I21.4 Acute subendocardial myocardial infarction
0.000 0.767 0.233
I61.3 Intracerebral haemorrhage in brain stem
0.000 0.771 0.229
I05 Rheumatic mitral valve diseases
0.000 0.776 0.224
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.781 0.219
I67.0 Dissection of cerebral arteries, nonruptured
0.000 0.782 0.218
E14.3 With ophthalmic complications
0.000 0.787 0.213
I05.2 Mitral stenosis with insufficiency
0.000 0.787 0.213
I60.4 Subarachnoid haemorrhage from basilar artery
0.000 0.790 0.209
I67.7 Cerebral arteritis, not elsewhere classified
0.000 0.794 0.206
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.000 0.794 0.206
I67.5 Moyamoya disease
0.000 0.794 0.206
I67.4 Hypertensive encephalopathy
0.000 0.794 0.206
I67.3 Progressive vascular leukoencephalopathy
0.000 0.794 0.206
I00-I02 Acute rheumatic fever
0.000 0.797 0.202
E14.6 With other specified complications
0.000 0.807 0.193
I62.1 Nontraumatic extradural haemorrhage
0.000 0.807 0.193
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.807 0.193
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.808 0.192
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.809 0.191
I68.0 Cerebral amyloid angiopathy
0.000 0.819 0.181
I61.4 Intracerebral haemorrhage in cerebellum
0.000 0.822 0.178
I13 Hypertensive heart and renal disease
0.000 0.823 0.177
I05.9 Mitral valve disease, unspecified
0.000 0.825 0.175
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.827 0.173
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.000 0.827 0.172
E70-E90 Metabolic disorders
0.000 0.828 0.172
I05.1 Rheumatic mitral insufficiency
0.000 0.830 0.170
I61.6 Intracerebral haemorrhage, multiple localised
0.000 0.830 0.169
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.000 0.831 0.169
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.000 0.831 0.169
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.000 0.831 0.169
I61.5 Intracerebral haemorrhage, intraventricular
0.000 0.832 0.168
E14.1 With ketoacidosis
0.000 0.833 0.167
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.000 0.833 0.167
T36-T50 Poisoning by drugs, medicaments and biological substances
0.166 0.834 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.163 0.837 0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.000 0.837 0.162
I66.3 Occlusion and stenosis of cerebellar arteries
0.000 0.839 0.161
I05.8 Other mitral valve diseases
0.000 0.839 0.161
I05.0 Mitral stenosis
0.000 0.840 0.160
I09 Other rheumatic heart diseases
0.000 0.842 0.158
T42.4 Benzodiazepines
0.158 0.842 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.842 0.158
I66.0 Occlusion and stenosis of middle cerebral artery
0.000 0.843 0.157
I66.8 Occlusion and stenosis of other cerebral artery
0.000 0.843 0.157
I66.2 Occlusion and stenosis of posterior cerebral artery
0.000 0.843 0.157
I66.1 Occlusion and stenosis of anterior cerebral artery
0.000 0.843 0.157
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.155 0.845 0.000
I69 Sequelae of cerebrovascular disease
0.000 0.846 0.154
T46 Poisoning by agents primarily affecting the cardiovascular system
0.154 0.846 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.154 0.846 0.000
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.000 0.847 0.153
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.000 0.849 0.151
I07 Rheumatic tricuspid valve diseases
0.000 0.849 0.151
I61.8 Other intracerebral haemorrhage
0.000 0.850 0.150
T50.9 Other and unspecified drugs, medicaments and biological substances
0.149 0.851 0.000
E16 Other disorders of pancreatic internal secretion
0.000 0.852 0.147
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.147 0.853 0.000
I02 Rheumatic chorea
0.000 0.854 0.145
I01 Rheumatic fever with heart involvement
0.000 0.854 0.145
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.855 0.145
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.856 0.144
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.143 0.857 0.000
E16.2 Hypoglycaemia, unspecified
0.000 0.858 0.142
I69.1 Sequelae of intracerebral haemorrhage
0.000 0.859 0.141
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.141 0.859 0.000
I15 Secondary hypertension
0.000 0.862 0.138
E73 Lactose intolerance
0.000 0.863 0.137
E85 Amyloidosis
0.000 0.865 0.135
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.134 0.866 0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.134 0.866 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.132 0.868 0.000
I00 Rheumatic fever without mention of heart involvement
0.000 0.869 0.131
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified
0.131 0.869 0.000
T42.0 Hydantoin derivatives
0.130 0.870 0.000
T40.6 Other and unspecified narcotics
0.129 0.871 0.000
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.873 0.127
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.873 0.127
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.873 0.127
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.873 0.127
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.127 0.873 0.000
I08 Multiple valve diseases
0.000 0.875 0.125
T46.1 Calcium-channel blockers
0.125 0.875 0.000
T40.2 Other opioids
0.125 0.875 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.125 0.875 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.124 0.876 0.000
T46.3 Coronary vasodilators, not elsewhere classified
0.124 0.876 0.000
I06 Rheumatic aortic valve diseases
0.000 0.876 0.124
E77 Disorders of glycoprotein metabolism
0.000 0.876 0.123
E76 Disorders of glycosaminoglycan metabolism
0.000 0.876 0.123
E72 Other disorders of amino-acid metabolism
0.000 0.876 0.123
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.876 0.123
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.876 0.123
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.877 0.123
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.123 0.877 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.123 0.877 0.000
I11 Hypertensive heart disease
0.000 0.878 0.122
T38.1 Thyroid hormones and substitutes
0.122 0.878 0.000
E79 Disorders of purine and pyrimidine metabolism
0.000 0.878 0.122
T47.1 Other antacids and anti-gastric-secretion drugs
0.122 0.878 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.120 0.880 0.000
I12 Hypertensive renal disease
0.000 0.881 0.119
T41 Poisoning by anaesthetics and therapeutic gases
0.119 0.881 0.000
T42.3 Barbiturates
0.119 0.881 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.117 0.883 0.000
T42.2 Succinimides and oxazolidinediones
0.117 0.883 0.000
T36 Poisoning by systemic antibiotics
0.115 0.885 0.000
I08.8 Other multiple valve diseases
0.000 0.885 0.115
E70 Disorders of aromatic amino-acid metabolism
0.000 0.886 0.114
I09.8 Other specified rheumatic heart diseases
0.000 0.886 0.114
I09.2 Chronic rheumatic pericarditis
0.000 0.886 0.114
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.886 0.114
I09.0 Rheumatic myocarditis
0.000 0.886 0.114
T46.5 Other antihypertensive drugs, not elsewhere classified
0.114 0.886 0.000
E15 Nondiabetic hypoglycaemic coma
0.000 0.886 0.113
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.887 0.113
E85.4 Organ-limited amyloidosis
0.000 0.887 0.113
T43.5 Other and unspecified antipsychotics and neuroleptics
0.113 0.887 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.112 0.888 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.112 0.888 0.000
E73.9 Lactose intolerance, unspecified
0.000 0.888 0.112
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.889 0.111
T38.9 Other and unspecified hormone antagonists
0.111 0.889 0.000
T38.8 Other and unspecified hormones and their synthetic substitutes
0.111 0.889 0.000
T38.7 Androgens and anabolic congeners
0.111 0.889 0.000
T38.5 Other oestrogens and progestogens
0.111 0.889 0.000
T38.4 Oral contraceptives
0.111 0.889 0.000
T38.2 Antithyroid drugs
0.111 0.889 0.000
T38.0 Glucocorticoids and synthetic analogues
0.111 0.889 0.000
T40.1 Heroin
0.111 0.889 0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.111 0.889 0.000
T46.8 Antivaricose drugs, including sclerosing agents
0.111 0.889 0.000
T46.7 Peripheral vasodilators
0.111 0.889 0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.111 0.889 0.000
T40.5 Cocaine
0.110 0.890 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.110 0.890 0.000
T50.7 Analeptics and opioid receptor antagonists
0.110 0.890 0.000
T50.5 Appetite depressants
0.110 0.890 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.110 0.890 0.000
T50.1 Loop [high-ceiling] diuretics
0.110 0.890 0.000
T50.0 Mineralocorticoids and their antagonists
0.110 0.890 0.000
T47.0 Histamine H(2)-receptor antagonists
0.110 0.890 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.109 0.891 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.891 0.109
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.891 0.109
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.109 0.891 0.000
I07.9 Tricuspid valve disease, unspecified
0.000 0.892 0.108
I07.8 Other tricuspid valve diseases
0.000 0.892 0.108
I07.2 Tricuspid stenosis with insufficiency
0.000 0.892 0.108
I07.0 Tricuspid stenosis
0.000 0.892 0.108
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.000 0.892 0.108
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.108 0.892 0.000
T43.6 Psychostimulants with abuse potential
0.107 0.893 0.000
T50.4 Drugs affecting uric acid metabolism
0.106 0.893 0.000
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.893 0.106
E84 Cystic fibrosis
0.000 0.894 0.106
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.894 0.106
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.894 0.106
E16.4 Abnormal secretion of gastrin
0.000 0.894 0.106
E16.3 Increased secretion of glucagon
0.000 0.894 0.106
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.105 0.895 0.000
T40.8 Lysergide [LSD]
0.105 0.895 0.000
T40.7 Cannabis (derivatives)
0.105 0.895 0.000
T40.3 Methadone
0.105 0.895 0.000
T40.0 Opium
0.105 0.895 0.000
T47.4 Other laxatives
0.105 0.895 0.000
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.895 0.104
I01.8 Other acute rheumatic heart disease
0.000 0.895 0.104
I01.2 Acute rheumatic myocarditis
0.000 0.895 0.104
I01.1 Acute rheumatic endocarditis
0.000 0.895 0.104
I01.0 Acute rheumatic pericarditis
0.000 0.895 0.104
I02.9 Rheumatic chorea without heart involvement
0.000 0.895 0.104
I02.0 Rheumatic chorea with heart involvement
0.000 0.895 0.104
I78 Diseases of capillaries
0.000 0.896 0.104
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.896 0.103
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.000 0.897 0.103
I09.9 Rheumatic heart disease, unspecified
0.000 0.897 0.103
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.103 0.897 0.000
T47.8 Other agents primarily affecting the gastro-intestinal system
0.103 0.897 0.000
T47.7 Emetics
0.103 0.897 0.000
T47.6 Antidiarrhoeal drugs
0.103 0.897 0.000
T47.5 Digestants
0.103 0.897 0.000
T47.3 Saline and osmotic laxatives
0.103 0.897 0.000
T47.2 Stimulant laxatives
0.103 0.897 0.000
T50.8 Diagnostic agents
0.102 0.898 0.000
E74 Other disorders of carbohydrate metabolism
0.000 0.898 0.102
T43.9 Psychotropic drug, unspecified
0.101 0.899 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.101 0.899 0.000
E85.9 Amyloidosis, unspecified
0.000 0.900 0.100
I15.8 Other secondary hypertension
0.000 0.901 0.099
I15.2 Hypertension secondary to endocrine disorders
0.000 0.901 0.099
T50.6 Antidotes and chelating agents, not elsewhere classified
0.098 0.901 0.000
E73.8 Other lactose intolerance
0.000 0.902 0.098
E73.1 Secondary lactase deficiency
0.000 0.902 0.098
E73.0 Congenital lactase deficiency
0.000 0.902 0.098
I65.1 Occlusion and stenosis of basilar artery
0.000 0.902 0.098
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.902 0.098
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.097 0.903 0.000
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.903 0.097
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.903 0.097
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.903 0.097
T42.1 Iminostilbenes
0.096 0.903 0.000
E16.1 Other hypoglycaemia
0.000 0.905 0.095
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.095 0.905 0.000
T37.8 Other specified systemic anti-infectives and antiparasitics
0.095 0.905 0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.095 0.905 0.000
I63 Cerebral infarction
0.000 0.906 0.094
I08.0 Disorders of both mitral and aortic valves
0.000 0.906 0.094
E85.3 Secondary systemic amyloidosis
0.000 0.906 0.094
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.907 0.093
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.907 0.093
I08.9 Multiple valve disease, unspecified
0.000 0.907 0.093
I21.9 Acute myocardial infarction, unspecified
0.000 0.907 0.093
I69.0 Sequelae of subarachnoid haemorrhage
0.000 0.909 0.091
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.090 0.909 0.000
T36.4 Tetracyclines
0.090 0.910 0.000
E80.2 Other porphyria
0.000 0.910 0.090
I07.1 Tricuspid insufficiency
0.000 0.910 0.090
T37.9 Systemic anti-infective and antiparasitic, unspecified
0.090 0.910 0.000
T37.5 Antiviral drugs
0.090 0.910 0.000
T37.4 Anthelminthics
0.090 0.910 0.000
T37.3 Other antiprotozoal drugs
0.090 0.910 0.000
T37.2 Antimalarials and drugs acting on other blood protozoa
0.090 0.910 0.000
T37.1 Antimycobacterial drugs
0.090 0.910 0.000
T37.0 Sulphonamides
0.090 0.910 0.000
I15.9 Seconday hypertension, unspecified
0.000 0.910 0.089
T49.9 Topical agent, unspecified
0.089 0.910 0.000
T49.8 Other topical agents
0.089 0.910 0.000
T49.7 Dental drugs, topically applied
0.089 0.910 0.000
T49.6 Otorhinolaryngological drugs and preparations
0.089 0.910 0.000
T49.5 Ophthalmological drugs and preparations
0.089 0.910 0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations
0.089 0.910 0.000
T49.3 Emollients, demulcents and protectants
0.089 0.910 0.000
T49.2 Local astringents and local detergents
0.089 0.910 0.000
T49.1 Antipruritics
0.089 0.910 0.000
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.911 0.089
I06.8 Other rheumatic aortic valve diseases
0.000 0.911 0.089
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.911 0.089
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.089 0.911 0.000
E71.3 Disorders of fatty-acid metabolism
0.000 0.911 0.089
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.911 0.089
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.911 0.089
E71.0 Maple-syrup-urine disease
0.000 0.911 0.089
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.911 0.089
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.911 0.089
E72.5 Disorders of glycine metabolism
0.000 0.911 0.089
E72.4 Disorders of ornithine metabolism
0.000 0.911 0.089
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.911 0.089
E72.2 Disorders of urea cycle metabolism
0.000 0.911 0.089
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.911 0.089
E72.0 Disorders of amino-acid transport
0.000 0.911 0.089
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.911 0.089
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.911 0.089
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.911 0.089
E76.2 Other mucopolysaccharidoses
0.000 0.911 0.089
E76.1 Mucopolysaccharidosis, type II
0.000 0.911 0.089
E76.0 Mucopolysaccharidosis, type I
0.000 0.911 0.089
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.911 0.089
E77.8 Other disorders of glycoprotein metabolism
0.000 0.911 0.089
E77.1 Defects in glycoprotein degradation
0.000 0.911 0.089
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.911 0.089
I67.8 Other specified cerebrovascular diseases
0.000 0.911 0.089
E75.6 Lipid storage disorder, unspecified
0.000 0.911 0.089
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.911 0.089
E75.3 Sphingolipidosis, unspecified
0.000 0.911 0.089
E75.2 Other sphingolipidosis
0.000 0.911 0.089
E75.1 Other gangliosidosis
0.000 0.911 0.089
E75.0 GM2 gangliosidosis
0.000 0.911 0.089
I15.1 Hypertension secondary to other renal disorders
0.000 0.911 0.088
E75.5 Other lipid storage disorders
0.000 0.911 0.088
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.088 0.912 0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.088 0.912 0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.088 0.912 0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.088 0.912 0.000
T44.1 Other parasympathomimetics [cholinergics]
0.088 0.912 0.000
T44.0 Anticholinesterase agents
0.088 0.912 0.000
I15.0 Renovascular hypertension
0.000 0.912 0.088
T43.2 Other and unspecified antidepressants
0.088 0.912 0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.912 0.088
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.912 0.088
E79.1 Lesch-Nyhan syndrome
0.000 0.912 0.088
E85.8 Other amyloidosis
0.000 0.913 0.087
E88 Other metabolic disorders
0.000 0.913 0.087
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.913 0.086
I70 Atherosclerosis
0.000 0.914 0.086
T41.5 Therapeutic gases
0.085 0.914 0.000
T41.4 Anaesthetic, unspecified
0.085 0.914 0.000
T41.3 Local anaesthetics
0.085 0.914 0.000
T41.2 Other and unspecified general anaesthetics
0.085 0.914 0.000
T41.1 Intravenous anaesthetics
0.085 0.914 0.000
T41.0 Inhaled anaesthetics
0.085 0.914 0.000
E40-E46 Malnutrition
0.000 0.915 0.085
I78.1 Naevus, nonneoplastic
0.000 0.915 0.085
E80.6 Other disorders of bilirubin metabolism
0.000 0.916 0.083
T36.9 Systemic antibiotic, unspecified
0.083 0.917 0.000
T36.8 Other systemic antibiotics
0.083 0.917 0.000
T36.7 Antifungal antibiotics, systemically used
0.083 0.917 0.000
T36.6 Rifamycins
0.083 0.917 0.000
T36.5 Aminoglycosides
0.083 0.917 0.000
T36.3 Macrolides
0.083 0.917 0.000
T36.2 Chloramphenicol group
0.083 0.917 0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics
0.083 0.917 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.918 0.082
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.918 0.082
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.918 0.082
E70.2 Disorders of tyrosine metabolism
0.000 0.918 0.082
E70.1 Other hyperphenylalaninaemias
0.000 0.918 0.082
E70.0 Classical phenylketonuria
0.000 0.918 0.082
I69.3 Sequelae of cerebral infarction
0.000 0.918 0.082
I74 Arterial embolism and thrombosis
0.000 0.919 0.081
T48.7 Other and unspecified agents primarily acting on the respiratory system
0.079 0.921 0.000
T48.5 Anti-common-cold drugs
0.079 0.921 0.000
T48.4 Expectorants
0.079 0.921 0.000
T48.3 Antitussives
0.079 0.921 0.000
T48.2 Other and unspecified agents primarily acting on muscles
0.079 0.921 0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]
0.079 0.921 0.000
T48.0 Oxytocic drugs
0.079 0.921 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.079 0.921 0.000
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.921 0.078
E80.5 Crigler-Najjar syndrome
0.000 0.921 0.078
E80.3 Defects of catalase and peroxydase
0.000 0.921 0.078
E80.0 Hereditary erythropoietic porphyria
0.000 0.921 0.078
I78.8 Other diseases of capillaries
0.000 0.922 0.078
I63.8 Other cerebral infarction
0.000 0.923 0.077
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.923 0.077
E84.8 Cystic fibrosis with other manifestations
0.000 0.923 0.076
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.923 0.076
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.923 0.076
E80.1 Porphyria cutanea tarda
0.000 0.924 0.076
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.924 0.076
I72 Other aneurysm
0.000 0.924 0.076
I78.9 Disease of capillaries, unspecified
0.000 0.925 0.075
I06.1 Rheumatic aortic insufficiency
0.001 0.925 0.074
I74.5 Embolism and thrombosis of iliac artery
0.000 0.926 0.074
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.000 0.926 0.074
I74.8 Embolism and thrombosis of other arteries
0.000 0.926 0.074
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.927 0.073
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.927 0.073
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.927 0.073
E74.2 Disorders of galactose metabolism
0.000 0.927 0.073
E74.1 Disorders of fructose metabolism
0.000 0.927 0.073
E74.0 Glycogen storage disease
0.000 0.927 0.073
E70.3 Albinism
0.000 0.927 0.073
I12.0 Hypertensive renal disease with renal failure
0.000 0.928 0.072
T45.0 Antiallergic and antiemetic drugs
0.071 0.929 0.000
T48.6 Antiasthmatics, not elsewhere classified
0.070 0.929 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.929 0.070
I70.1 Atherosclerosis of renal artery
0.000 0.930 0.070
T36.0 Penicillins
0.069 0.931 0.000
T45.9 Primarily systemic and haematological agent, unspecified
0.068 0.931 0.000
T45.8 Other primarily systemic and haematological agents
0.068 0.931 0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants
0.068 0.931 0.000
T45.6 Fibrinolysis-affecting drugs
0.068 0.931 0.000
T45.4 Iron and its compounds
0.068 0.931 0.000
T45.3 Enzymes, not elsewhere classified
0.068 0.931 0.000
I06.0 Rheumatic aortic stenosis
0.001 0.932 0.068
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.000 0.932 0.068
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.000 0.932 0.068
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.000 0.932 0.068
T40.4 Other synthetic narcotics
0.067 0.933 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.066 0.934 0.000
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.934 0.066
I28 Other diseases of pulmonary vessels
0.000 0.934 0.066
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.934 0.066
E50-E64 Other nutritional deficiencies
0.000 0.934 0.066
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.000 0.934 0.065
T45.1 Antineoplastic and immunosuppressive drugs
0.065 0.935 0.000
T45.2 Vitamins, not elsewhere classified
0.065 0.935 0.000
E88.9 Metabolic disorder, unspecified
0.000 0.937 0.063
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.939 0.061
E45 Retarded development following protein-energy malnutrition
0.000 0.939 0.061
E43 Unspecified severe protein-energy malnutrition
0.000 0.939 0.061
E42 Marasmic kwashiorkor
0.000 0.939 0.061
E41 Nutritional marasmus
0.000 0.939 0.061
E40 Kwashiorkor
0.000 0.939 0.061
I72.8 Aneurysm of other specified arteries
0.000 0.939 0.061
E89.0 Postprocedural hypothyroidism
0.000 0.939 0.061
I70.8 Atherosclerosis of other arteries
0.000 0.940 0.060

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

The contents of TreeWAS.org are available under the Creative Commons Attribution 4.0 International License (CC BY 4.0) with attribution (citation) required.

TreeWAS Database © 2019 - 2025 About Frequently Asked Questions Citation Contact Terms & Conditions This website does not use cookies to collect any personal information about you.