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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2968297
log Bayes Factor = 15.5449
Chromosome 5   position 63,558,925  (GRCh37) Explore rs2968297 on Ensembl!
Variant rs2968297 is part of Cluster X0192

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
M20-M25 Other joint disorders
0.999 0.001 0.000
M20 Acquired deformities of fingers and toes
0.999 0.001 0.000
Chapter II Neoplasms
0.998 0.002 0.000
Chapter IX Diseases of the circulatory system
0.997 0.003 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.997 0.003 0.000
M45-M49 Spondylopathies
0.997 0.003 0.000
R50-R69 General symptoms and signs
0.996 0.004 0.000
M20.1 Hallux valgus (acquired)
0.994 0.006 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.993 0.007 0.000
R51 Headache
0.988 0.012 0.000
M15-M19 Arthrosis
0.987 0.013 0.000
C15-C26 Malignant neoplasms of digestive organs
0.984 0.016 0.000
Chapter XI Diseases of the digestive system
0.979 0.021 0.000
I60-I69 Cerebrovascular diseases
0.978 0.022 0.000
M47 Spondylosis
0.978 0.022 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.973 0.027 0.000
C18 Malignant neoplasm of colon
0.973 0.027 0.000
I30-I52 Other forms of heart disease
0.972 0.028 0.000
R30-R39 Symptoms and signs involving the urinary system
0.971 0.029 0.000
M48 Other spondylopathies
0.967 0.033 0.000
M47.9 Spondylosis, unspecified
0.962 0.038 0.000
Chapter VI Diseases of the nervous system
0.961 0.039 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.961 0.039 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.961 0.039 0.000
I63 Cerebral infarction
0.957 0.043 0.000
R33 Retention of urine
0.957 0.043 0.000
K70-K77 Diseases of liver
0.956 0.044 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.951 0.049 0.000
R55 Syncope and collapse
0.949 0.051 0.000
M48.0 Spinal stenosis
0.946 0.054 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.933 0.067 0.000
M16 Coxarthrosis [arthrosis of hip]
0.932 0.068 0.000
I50 Heart failure
0.930 0.070 0.000
M20.3 Other deformity of hallux (acquired)
0.927 0.073 0.000
S00-S09 Injuries to the head
0.926 0.074 0.000
M48.06 Spinal stenosis (Lumbar region)
0.922 0.078 0.000
M80-M85 Disorders of bone density and structure
0.916 0.084 0.000
I20-I25 Ischaemic heart diseases
0.915 0.085 0.000
C77.2 Intra-abdominal lymph nodes
0.914 0.086 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.911 0.089 0.000
M18 Arthrosis of first carpometacarpal joint
0.910 0.090 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.908 0.092 0.000
M19 Other arthrosis
0.908 0.092 0.000
I50.1 Left ventricular failure
0.908 0.092 0.000
I63.9 Cerebral infarction, unspecified
0.905 0.095 0.000
M16.1 Other primary coxarthrosis
0.902 0.098 0.000
C79 Secondary malignant neoplasm of other sites
0.901 0.099 0.000
K12 Stomatitis and related lesions
0.896 0.104 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.894 0.106 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.892 0.108 0.000
M20.4 Other hammer toe(s) (acquired)
0.888 0.112 0.000
K08 Other disorders of teeth and supporting structures
0.882 0.118 0.000
C18.9 Colon, unspecified
0.878 0.122 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.873 0.127 0.000
M50-M54 Other dorsopathies
0.872 0.128 0.000
S80-S89 Injuries to the knee and lower leg
0.867 0.133 0.000
R50 Fever of unknown origin
0.866 0.134 0.000
K76 Other diseases of liver
0.865 0.135 0.000
R35 Polyuria
0.862 0.138 0.000
M40-M43 Deforming dorsopathies
0.862 0.138 0.000
K90-K93 Other diseases of the digestive system
0.861 0.139 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.859 0.141 0.000
I44 Atrioventricular and left bundle-branch block
0.859 0.141 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.852 0.148 0.000
C18.3 Hepatic flexure
0.852 0.148 0.000
C78.0 Secondary malignant neoplasm of lung
0.849 0.151 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.848 0.152 0.000
G90-G99 Other disorders of the nervous system
0.846 0.154 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.846 0.154 0.000
G40-G47 Episodic and paroxysmal disorders
0.846 0.154 0.000
M19.9 Arthrosis, unspecified
0.842 0.158 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.842 0.158 0.000
Chapter XX External causes of morbidity and mortality
0.837 0.163 0.000
S09 Other and unspecified injuries of head
0.836 0.164 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.829 0.171 0.000
Chapter X Diseases of the respiratory system
0.828 0.172 0.000
I45 Other conduction disorders
0.824 0.176 0.000
I20 Angina pectoris
0.824 0.176 0.000
D00-D09 In situ neoplasms
0.823 0.177 0.000
I60 Subarachnoid haemorrhage
0.823 0.177 0.000
M48.02 Spinal stenosis (Cervical region)
0.823 0.177 0.000
R68 Other general symptoms and signs
0.822 0.178 0.000
C78.7 Secondary malignant neoplasm of liver
0.821 0.179 0.000
K35-K38 Diseases of appendix
0.820 0.180 0.000
G40 Epilepsy
0.819 0.181 0.000
K70 Alcoholic liver disease
0.818 0.182 0.000
C18.2 Ascending colon
0.817 0.183 0.000
Chapter XXII Codes for special purposes
0.816 0.184 0.000
I05-I09 Chronic rheumatic heart diseases
0.816 0.184 0.000
K76.8 Other specified diseases of liver
0.815 0.185 0.000
K74 Fibrosis and cirrhosis of liver
0.813 0.186 0.000
T79-T79 Certain early complications of trauma
0.811 0.189 0.000
M20.5 Other deformities of toe(s) (acquired)
0.810 0.190 0.000
S00 Superficial injury of head
0.809 0.191 0.000
R54 Senility
0.809 0.191 0.000
M70-M79 Other soft tissue disorders
0.808 0.192 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.807 0.193 0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)
0.805 0.194 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.804 0.196 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.801 0.199 0.000
R30 Pain associated with micturition
0.800 0.200 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.799 0.201 0.000
K08.3 Retained dental root
0.798 0.202 0.000
I62 Other nontraumatic intracranial haemorrhage
0.798 0.202 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.797 0.203 0.000
C15 Malignant neoplasm of oesophagus
0.796 0.204 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.796 0.204 0.000
K50-K52 Noninfective enteritis and colitis
0.793 0.207 0.000
C18.1 Appendix
0.793 0.207 0.000
T66-T78 Other and unspecified effects of external causes
0.792 0.208 0.000
R50.9 Fever, unspecified
0.790 0.210 0.000
K75 Other inflammatory liver diseases
0.790 0.210 0.000
C18.7 Sigmoid colon
0.789 0.211 0.000
I69 Sequelae of cerebrovascular disease
0.788 0.212 0.000
M80 Osteoporosis with pathological fracture
0.788 0.212 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.786 0.214 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.786 0.214 0.000
R21 Rash and other nonspecific skin eruption
0.784 0.216 0.000
K00 Disorders of tooth development and eruption
0.783 0.217 0.000
G40.9 Epilepsy, unspecified
0.781 0.219 0.000
C64-C68 Malignant neoplasms of urinary tract
0.780 0.220 0.000
M81 Osteoporosis without pathological fracture
0.778 0.222 0.000
I21 Acute myocardial infarction
0.778 0.222 0.000
G93 Other disorders of brain
0.777 0.223 0.000
C78.2 Secondary malignant neoplasm of pleura
0.774 0.226 0.000
S09.9 Unspecified injury of head
0.772 0.228 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.772 0.228 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.769 0.231 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.767 0.233 0.000
S80 Superficial injury of lower leg
0.767 0.233 0.000
S90-S99 Injuries to the ankle and foot
0.763 0.237 0.000
S50-S59 Injuries to the elbow and forearm
0.762 0.237 0.000
M16.7 Other secondary coxarthrosis
0.762 0.238 0.000
I44.2 Atrioventricular block, complete
0.762 0.238 0.000
M34 Systemic sclerosis
0.762 0.238 0.000
Chapter VII Diseases of the eye and adnexa
0.762 0.238 0.000
K12.3 Oral mucositis (ulcerative)
0.761 0.239 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.761 0.239 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.761 0.239 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.761 0.239 0.000
T39.1 4-Aminophenol derivatives
0.761 0.239 0.000
M35 Other systemic involvement of connective tissue
0.760 0.240 0.000
Chapter VIII Diseases of the ear and mastoid process
0.759 0.241 0.000
I49 Other cardiac arrhythmias
0.758 0.242 0.000
C16 Malignant neoplasm of stomach
0.758 0.242 0.000
I61 Intracerebral haemorrhage
0.756 0.244 0.000
M22 Disorders of patella
0.756 0.244 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.752 0.248 0.000
M43 Other deforming dorsopathies
0.752 0.248 0.000
I34 Nonrheumatic mitral valve disorders
0.751 0.249 0.000
M51 Other intervertebral disk disorders
0.749 0.251 0.000
I30 Acute pericarditis
0.749 0.251 0.000
L60-L75 Disorders of skin appendages
0.749 0.251 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.747 0.253 0.000
M16.0 Primary coxarthrosis, bilateral
0.747 0.253 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.747 0.253 0.000
C77.5 Intrapelvic lymph nodes
0.747 0.253 0.000
K12.2 Cellulitis and abscess of mouth
0.747 0.253 0.000
M20.0 Deformity of finger(s)
0.746 0.254 0.000
G81 Hemiplegia
0.745 0.255 0.000
S70-S79 Injuries to the hip and thigh
0.745 0.255 0.000
K12.1 Other forms of stomatitis
0.745 0.255 0.000
C18.0 Caecum
0.744 0.256 0.000
Chapter V Mental and behavioural disorders
0.744 0.256 0.000
S20-S29 Injuries to the thorax
0.741 0.259 0.000
M47.8 Other spondylosis
0.741 0.259 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.741 0.259 0.000
I50.9 Heart failure, unspecified
0.741 0.259 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.741 0.259 0.000
I35 Nonrheumatic aortic valve disorders
0.740 0.260 0.000
K11 Diseases of salivary glands
0.740 0.260 0.000
M21 Other acquired deformities of limbs
0.739 0.260 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.739 0.261 0.000
G30-G32 Other degenerative diseases of the nervous system
0.739 0.261 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.737 0.263 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.737 0.263 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.736 0.264 0.000
J30-J39 Other diseases of upper respiratory tract
0.735 0.265 0.000
C51-C58 Malignant neoplasms of female genital organs
0.735 0.265 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.733 0.267 0.000
M86-M90 Other osteopathies
0.732 0.268 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.731 0.269 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.730 0.270 0.000
J95-J99 Other diseases of the respiratory system
0.729 0.271 0.000
R61 Hyperhidrosis
0.726 0.274 0.000
M19.98 Arthrosis, unspecified (Other)
0.726 0.274 0.000
M54 Dorsalgia
0.725 0.274 0.000
S60-S69 Injuries to the wrist and hand
0.725 0.275 0.000
M20.2 Hallux rigidus
0.725 0.275 0.000
I24 Other acute ischaemic heart diseases
0.725 0.275 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.724 0.276 0.000
W00-W19 Falls
0.719 0.281 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.718 0.281 0.000
K02 Dental caries
0.718 0.282 0.000
M24 Other specific joint derangements
0.717 0.283 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.717 0.283 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.716 0.284 0.000
M33 Dermatopolymyositis
0.716 0.284 0.000
M32 Systemic lupus erythematosus
0.716 0.284 0.000
M30 Polyarteritis nodosa and related conditions
0.716 0.284 0.000
M19.96 Arthrosis, unspecified-Lower leg
0.716 0.284 0.000
R60 Oedema, not elsewhere classified
0.716 0.284 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.715 0.284 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.715 0.284 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.715 0.284 0.000
I00-I02 Acute rheumatic fever
0.715 0.285 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.715 0.285 0.000
M49 Spondylopathies in diseases classified elsewhere
0.714 0.285 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.714 0.286 0.000
R62 Lack of expected normal physiological development
0.714 0.286 0.000
R57 Shock, not elsewhere classified
0.714 0.286 0.000
R64 Cachexia
0.714 0.286 0.000
R58 Haemorrhage, not elsewhere classified
0.714 0.286 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.714 0.286 0.000
R52 Pain, not elsewhere classified
0.714 0.286 0.000
I33 Acute and subacute endocarditis
0.713 0.287 0.000
K90 Intestinal malabsorption
0.713 0.287 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.712 0.288 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.712 0.288 0.000
K09 Cysts of oral region, not elsewhere classified
0.710 0.290 0.000
M46 Other inflammatory spondylopathies
0.708 0.292 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.708 0.292 0.000
M15 Polyarthrosis
0.708 0.292 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.707 0.293 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.706 0.294 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.706 0.294 0.000
C21 Malignant neoplasm of anus and anal canal
0.706 0.294 0.000
C17 Malignant neoplasm of small intestine
0.706 0.294 0.000
C23 Malignant neoplasm of gallbladder
0.706 0.294 0.000
Q50-Q56 Congenital malformations of genital organs
0.706 0.294 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.705 0.295 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.704 0.296 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.703 0.297 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.701 0.299 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.701 0.299 0.000
I20.9 Angina pectoris, unspecified
0.701 0.299 0.000
Chapter XIV Diseases of the genitourinary system
0.701 0.299 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.701 0.299 0.000
M47.2 Other spondylosis with radiculopathy
0.701 0.299 0.000
M47.1 Other spondylosis with myelopathy
0.701 0.299 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.701 0.299 0.000
G20-G26 Extrapyramidal and movement disorders
0.701 0.299 0.000
I31 Other diseases of pericardium
0.699 0.301 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.699 0.301 0.000
R68.8 Other specified general symptoms and signs
0.698 0.302 0.000
K08.8 Other specified disorders of teeth and supporting structures
0.698 0.302 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.698 0.302 0.000
T87 Complications peculiar to reattachment and amputation
0.698 0.302 0.000
T86 Failure and rejection of transplanted organs and tissues
0.698 0.302 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.698 0.302 0.000
C18.8 Overlapping lesion of colon
0.697 0.303 0.000
C18.6 Descending colon
0.697 0.303 0.000
C18.5 Splenic flexure
0.697 0.303 0.000
I52 Other heart disorders in diseases classified elsewhere
0.697 0.303 0.000
I48 Atrial fibrillation and flutter
0.697 0.303 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.697 0.303 0.000
I41 Myocarditis in diseases classified elsewhere
0.697 0.303 0.000
I40 Acute myocarditis
0.697 0.303 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.697 0.303 0.000
I37 Pulmonary valve disorders
0.697 0.303 0.000
I36 Nonrheumatic tricuspid valve disorders
0.697 0.303 0.000
I32 Pericarditis in diseases classified elsewhere
0.697 0.303 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.697 0.303 0.000
K14 Diseases of tongue
0.697 0.303 0.000
R36 Urethral discharge
0.696 0.304 0.000
R34 Anuria and oliguria
0.696 0.304 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.696 0.304 0.000
C18.4 Transverse colon
0.696 0.304 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.696 0.304 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.695 0.305 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.695 0.305 0.000
M19.97 Arthrosis, unspecified (Ankle and foot)
0.695 0.305 0.000
R73 Elevated blood glucose level
0.695 0.305 0.000
C77.0 Lymph nodes of head, face and neck
0.694 0.306 0.000
M48.9 Spondylopathy, unspecified
0.693 0.307 0.000
M48.8 Other specified spondylopathies
0.693 0.307 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.693 0.307 0.000
M48.4 Fatigue fracture of vertebra
0.693 0.307 0.000
M48.3 Traumatic spondylopathy
0.693 0.307 0.000
M48.2 Kissing spine
0.693 0.307 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.693 0.307 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.692 0.308 0.000
S86 Injury of muscle and tendon at lower leg level
0.691 0.309 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.690 0.310 0.000
M19.91 Arthrosis, unspecified (Shoulder region)
0.690 0.310 0.000
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)
0.690 0.310 0.000
M47.95 Spondylosis, unspecified (Thoracolumbar region)
0.690 0.310 0.000
M47.94 Spondylosis, unspecified (Thoracic region)
0.690 0.310 0.000
M47.93 Spondylosis, unspecified (Cervicothoracic region)
0.690 0.310 0.000
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)
0.690 0.310 0.000
G70-G73 Diseases of myoneural junction and muscle
0.689 0.311 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.689 0.311 0.000
K10 Other diseases of jaws
0.689 0.311 0.000
K07 Dentofacial anomalies [including malocclusion]
0.689 0.311 0.000
K03 Other diseases of hard tissues of teeth
0.689 0.311 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.689 0.311 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.689 0.311 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.689 0.311 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.689 0.311 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.689 0.311 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.689 0.311 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.689 0.311 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.689 0.311 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.689 0.311 0.000
T36 Poisoning by systemic antibiotics
0.689 0.311 0.000
K04 Diseases of pulp and periapical tissues
0.689 0.311 0.000
R56 Convulsions, not elsewhere classified
0.689 0.311 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.689 0.311 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.688 0.312 0.000
M05-M14 Inflammatory polyarthropathies
0.688 0.312 0.000
M19.0 Primary arthrosis of other joints
0.688 0.312 0.000
K50 Crohn's disease [regional enteritis]
0.688 0.312 0.000
M19.93 Arthrosis, unspecified (Forearm)
0.688 0.312 0.000
K70.9 Alcoholic liver disease, unspecified
0.688 0.312 0.000
I63.8 Other cerebral infarction
0.686 0.313 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.686 0.313 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.686 0.313 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.686 0.313 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.686 0.313 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.686 0.313 0.000
M31 Other necrotising vasculopathies
0.686 0.314 0.000
K77 Liver disorders in diseases classified elsewhere
0.686 0.314 0.000
K73 Chronic hepatitis, not elsewhere classified
0.686 0.314 0.000
K71 Toxic liver disease
0.686 0.314 0.000
M84 Disorders of continuity of bone
0.685 0.315 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.685 0.315 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.684 0.316 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.682 0.318 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.682 0.318 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.682 0.318 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.682 0.318 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.682 0.318 0.000
K05 Gingivitis and periodontal diseases
0.680 0.320 0.000
I08 Multiple valve diseases
0.679 0.321 0.000
H80-H83 Diseases of inner ear
0.679 0.321 0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)
0.678 0.322 0.000
M48.05 Spinal stenosis (Thoracolumbar region)
0.678 0.322 0.000
M48.04 Spinal stenosis (Thoracic region)
0.678 0.322 0.000
M48.03 Spinal stenosis (Cervicothoracic region)
0.678 0.322 0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)
0.678 0.322 0.000
M48.00 Spinal stenosis (Multiple sites in spine)
0.678 0.322 0.000
K74.6 Other and unspecified cirrhosis of liver
0.678 0.322 0.000
R30.0 Dysuria
0.678 0.322 0.000
K35 Acute appendicitis
0.678 0.322 0.000
C80 Malignant neoplasm without specification of site
0.678 0.322 0.000
T40.2 Other opioids
0.677 0.323 0.000
I67 Other cerebrovascular diseases
0.677 0.323 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.676 0.324 0.000
S81 Open wound of lower leg
0.675 0.324 0.000
C25 Malignant neoplasm of pancreas
0.675 0.325 0.000
Chapter I Certain infectious and parasitic diseases
0.675 0.325 0.000
I44.1 Atrioventricular block, second degree
0.675 0.325 0.000
R39 Other symptoms and signs involving the urinary system
0.674 0.326 0.000
I38 Endocarditis, valve unspecified
0.674 0.326 0.000
E70-E90 Metabolic disorders
0.673 0.327 0.000
M43.1 Spondylolisthesis
0.673 0.327 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.672 0.328 0.000
G81.9 Hemiplegia, unspecified
0.672 0.328 0.000
J32 Chronic sinusitis
0.671 0.329 0.000
K72 Hepatic failure, not elsewhere classified
0.669 0.331 0.000
C77.8 Lymph nodes of multiple regions
0.669 0.331 0.000
C77.4 Inguinal and lower limb lymph nodes
0.669 0.331 0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.669 0.331 0.000
M16.6 Other secondary coxarthrosis, bilateral
0.668 0.332 0.000
M16.5 Other posttraumatic coxarthrosis
0.668 0.332 0.000
M16.4 Posttraumatic coxarthrosis, bilateral
0.668 0.332 0.000
M16.3 Other dysplastic coxarthrosis
0.668 0.332 0.000
M16.2 Coxarthrosis resulting from dysplasia, bilateral
0.668 0.332 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.667 0.333 0.000
R20 Disturbances of skin sensation
0.667 0.333 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.667 0.333 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.666 0.334 0.000
M18.1 Other primary arthrosis of first carpometacarpal joint
0.665 0.334 0.000
R47-R49 Symptoms and signs involving speech and voice
0.665 0.334 0.000
S06 Intracranial injury
0.665 0.335 0.000
S40-S49 Injuries to the shoulder and upper arm
0.664 0.336 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.664 0.336 0.000
I42 Cardiomyopathy
0.664 0.336 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.664 0.336 0.000
S08 Traumatic amputation of part of head
0.664 0.336 0.000
S07 Crushing injury of head
0.664 0.336 0.000
S05 Injury of eye and orbit
0.664 0.336 0.000
S04 Injury of cranial nerves
0.664 0.336 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.664 0.336 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.663 0.337 0.000
G93.2 Benign intracranial hypertension
0.661 0.339 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.661 0.339 0.000
I20.0 Unstable angina
0.661 0.339 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.661 0.339 0.000
M81.9 Osteoporosis, unspecified
0.661 0.339 0.000
T39.0 Salicylates
0.660 0.339 0.000
C79.2 Secondary malignant neoplasm of skin
0.660 0.340 0.000
I45.5 Other specified heart block
0.660 0.340 0.000
M65-M68 Disorders of synovium and tendon
0.658 0.342 0.000
D05 Carcinoma in situ of breast
0.658 0.342 0.000
M48.09 Spinal stenosis (Site unspecified)
0.657 0.343 0.000
G83 Other paralytic syndromes
0.657 0.343 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.657 0.343 0.000
M85 Other disorders of bone density and structure
0.656 0.343 0.000
M83 Adult osteomalacia
0.656 0.343 0.000
M82 Osteoporosis in diseases classified elsewhere
0.656 0.343 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.656 0.343 0.000
I23 Certain current complications following acute myocardial infarction
0.656 0.344 0.000
M35.0 Sicca syndrome [Sjogren]
0.656 0.344 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.656 0.344 0.000
K00.6 Disturbances in tooth eruption
0.656 0.344 0.000
M54.5 Low back pain
0.654 0.346 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.653 0.346 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.653 0.346 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.653 0.346 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.653 0.347 0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint
0.653 0.347 0.000
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral
0.653 0.347 0.000
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint
0.653 0.347 0.000
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral
0.653 0.347 0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral
0.653 0.347 0.000
L84 Corns and callosities
0.652 0.348 0.000
N20-N23 Urolithiasis
0.652 0.348 0.000
M19.8 Other specified arthrosis
0.651 0.349 0.000
M19.2 Other secondary arthrosis
0.651 0.349 0.000
M19.1 Posttraumatic arthrosis of other joints
0.651 0.349 0.000
K91.4 Colostomy and enterostomy malfunction
0.650 0.349 0.000
M45 Ankylosing spondylitis
0.650 0.349 0.000
K76.9 Liver disease, unspecified
0.650 0.350 0.000
K08.9 Disorder of teeth and supporting structures, unspecified
0.650 0.350 0.000
J98 Other respiratory disorders
0.650 0.350 0.000
H30-H36 Disorders of choroid and retina
0.647 0.353 0.000
V80-V89 Other land transport accidents
0.646 0.354 0.000
C79.6 Secondary malignant neoplasm of ovary
0.646 0.354 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.646 0.354 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.646 0.354 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.646 0.354 0.000
M71 Other bursopathies
0.645 0.355 0.000
C22.9 Liver, unspecified
0.643 0.356 0.000
T78 Adverse effects, not elsewhere classified
0.643 0.357 0.000
K76.6 Portal hypertension
0.643 0.357 0.000
M41 Scoliosis
0.643 0.357 0.000
L20-L30 Dermatitis and eczema
0.642 0.358 0.000
K12.0 Recurrent oral aphthae
0.642 0.358 0.000
I45.9 Conduction disorder, unspecified
0.642 0.358 0.000
M19.92 Arthrosis, unspecified (Upper arm)
0.642 0.358 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.641 0.358 0.000
K70.3 Alcoholic cirrhosis of liver
0.641 0.359 0.000
R23 Other skin changes
0.641 0.359 0.000
S00.0 Superficial injury of scalp
0.640 0.360 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.639 0.360 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.639 0.360 0.000
T85.2 Mechanical complication of intraocular lens
0.639 0.360 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.639 0.360 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.639 0.360 0.000
K74.3 Primary biliary cirrhosis
0.639 0.361 0.000
G44 Other headache syndromes
0.638 0.362 0.000
M22.2 Patellofemoral disorders
0.637 0.363 0.000
I22 Subsequent myocardial infarction
0.637 0.363 0.000
I49.9 Cardiac arrhythmia, unspecified
0.636 0.364 0.000
R53 Malaise and fatigue
0.635 0.365 0.000
K75.4 Autoimmune hepatitis
0.635 0.365 0.000
M47.86 Other spondylosis (Lumbar region)
0.634 0.365 0.000
S01 Open wound of head
0.634 0.366 0.000
K37 Unspecified appendicitis
0.634 0.366 0.000
L50-L54 Urticaria and erythema
0.633 0.367 0.000
S00.9 Superficial injury of head, part unspecified
0.633 0.367 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.633 0.367 0.000
R63 Symptoms and signs concerning food and fluid intake
0.632 0.368 0.000
K08.2 Atrophy of edentulous alveolar ridge
0.632 0.368 0.000
K08.1 Loss of teeth due to accident, extraction or local periodontal disease
0.632 0.368 0.000
K08.0 Exfoliation of teeth due to systemic causes
0.632 0.368 0.000
C15.9 Oesophagus, unspecified
0.632 0.368 0.000
L91 Hypertrophic disorders of skin
0.631 0.369 0.000
G95 Other diseases of spinal cord
0.631 0.369 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.630 0.369 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.630 0.370 0.000
D03 Melanoma in situ
0.629 0.371 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.629 0.371 0.000
M77 Other enthesopathies
0.629 0.371 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.628 0.372 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.628 0.372 0.000
T42.4 Benzodiazepines
0.628 0.372 0.000
I20.8 Other forms of angina pectoris
0.627 0.372 0.000
S80.9 Superficial injury of lower leg, unspecified
0.627 0.373 0.000
M25 Other joint disorders, not elsewhere classified
0.627 0.373 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.626 0.374 0.000
M53 Other dorsopathies, not elsewhere classified
0.625 0.374 0.000
K13 Other diseases of lip and oral mucosa
0.624 0.376 0.000
K91.0 Vomiting following gastro-intestinal surgery
0.624 0.376 0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)
0.623 0.377 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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