TreeWAS – Variant ID: rs3094609

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E78.0 Pure hypercholesterolaemia	0.000	0.000	1.000
E83.1 Disorders of iron metabolism	1.000	0.000	0.000
K90.0 Coeliac disease	0.000	0.000	1.000
L40.9 Psoriasis, unspecified	0.000	0.000	1.000
E10 Insulin-dependent diabetes mellitus	0.000	0.000	1.000
G35 Multiple sclerosis	1.000	0.000	0.000
I25 Chronic ischaemic heart disease	0.000	0.000	1.000
E10-E14 Diabetes mellitus	0.000	0.000	1.000
I20-I25 Ischaemic heart diseases	0.000	0.000	1.000
E10.9 Without complications	0.000	0.000	1.000
L40 Psoriasis	0.000	0.000	1.000
M06.9 Rheumatoid arthritis, unspecified	0.000	0.000	1.000
E11 Non-insulin-dependent diabetes mellitus	0.000	0.001	0.999
I25.2 Old myocardial infarction	0.000	0.001	0.999
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.001	0.999
E11.9 Without complications	0.000	0.001	0.999
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.001	0.999
I25.1 Atherosclerotic heart disease	0.000	0.001	0.999
L40.5 Arthropathic psoriasis	0.000	0.003	0.997
I25.8 Other forms of chronic ischaemic heart disease	0.000	0.004	0.996
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.004	0.996
I10 Essential (primary) hypertension	0.000	0.005	0.995
I10-I15 Hypertensive diseases	0.000	0.006	0.994
E14 Unspecified diabetes mellitus	0.000	0.008	0.992
E70-E90 Metabolic disorders	0.000	0.009	0.991
L40-L45 Papulosquamous disorders	0.000	0.009	0.991
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.012	0.988
Chapter IX Diseases of the circulatory system	0.000	0.013	0.987
I21 Acute myocardial infarction	0.000	0.013	0.987
E14.9 Without complications	0.000	0.014	0.986
M06 Other rheumatoid arthritis	0.000	0.017	0.983
E10.3 With ophthalmic complications	0.000	0.027	0.973
I25.5 Ischaemic cardiomyopathy	0.000	0.028	0.972
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.029	0.971
I21.9 Acute myocardial infarction, unspecified	0.000	0.032	0.968
M05-M14 Inflammatory polyarthropathies	0.000	0.033	0.967
M45.X9 Ankylosing spondylitis (Site unspecified)	0.000	0.034	0.966
M45 Ankylosing spondylitis	0.000	0.035	0.965
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.000	0.038	0.962
J45.9 Asthma, unspecified	0.000	0.040	0.960
M45-M49 Spondylopathies	0.000	0.040	0.960
L43 Lichen planus	0.000	0.040	0.960
I12 Hypertensive renal disease	0.000	0.040	0.960
I22 Subsequent myocardial infarction	0.000	0.042	0.958
M70-M79 Other soft tissue disorders	0.000	0.043	0.957
# Top node	0.000	0.046	0.954
M79 Other soft tissue disorders, not elsewhere classified	0.000	0.055	0.945
I24 Other acute ischaemic heart diseases	0.000	0.061	0.939
K90 Intestinal malabsorption	0.000	0.061	0.939
M79.6 Pain in limb	0.000	0.062	0.938
L43.9 Lichen planus, unspecified	0.000	0.064	0.936
I22.1 Subsequent myocardial infarction of inferior wall	0.000	0.066	0.934
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.000	0.068	0.932
K51.9 Ulcerative colitis, unspecified	0.928	0.072	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.000	0.073	0.927
K51 Ulcerative colitis	0.926	0.074	0.000
M79.65 Pain in limb (Pelvic region and thigh)	0.000	0.077	0.923
I20 Angina pectoris	0.000	0.078	0.922
I21.4 Acute subendocardial myocardial infarction	0.000	0.080	0.920
M75 Shoulder lesions	0.000	0.081	0.919
I12.9 Hypertensive renal disease without renal failure	0.000	0.083	0.917
E78.2 Mixed hyperlipidaemia	0.000	0.087	0.913
M75.0 Adhesive capsulitis of shoulder	0.000	0.090	0.910
G35-G37 Demyelinating diseases of the central nervous system	0.901	0.099	0.000
E78.8 Other disorders of lipoprotein metabolism	0.000	0.102	0.898
E11.0 With coma	0.000	0.104	0.896
I20.9 Angina pectoris, unspecified	0.000	0.106	0.894
K90-K93 Other diseases of the digestive system	0.000	0.110	0.890
M79.7 Fibromyalgia	0.000	0.111	0.889
Chapter XI Diseases of the digestive system	0.000	0.114	0.886
K58.0 Irritable bowel syndrome with diarrhoea	0.000	0.114	0.886
K57 Diverticular disease of intestine	0.000	0.115	0.885
K55-K64 Other diseases of intestines	0.000	0.115	0.885
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.117	0.883
K58 Irritable bowel syndrome	0.000	0.118	0.882
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.000	0.121	0.879
K57.3 Diverticular disease of large intestine without perforation or abscess	0.000	0.123	0.877
G37 Other demyelinating diseases of central nervous system	0.865	0.135	0.000
K51.3 Ulcerative (chronic) rectosigmoiditis	0.865	0.135	0.000
K51.8 Other ulcerative colitis	0.865	0.135	0.000
M07 Psoriatic and enteropathic arthropathies	0.000	0.138	0.862
M79.79 Fibromyalgia (Site unspecified)	0.000	0.138	0.862
L40.0 Psoriasis vulgaris	0.000	0.139	0.861
M79.1 Myalgia	0.000	0.148	0.852
L40.8 Other psoriasis	0.000	0.153	0.847
M70 Soft tissue disorders related to use, overuse and pressure	0.000	0.155	0.845
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.155	0.845
E10.1 With ketoacidosis	0.000	0.155	0.844
K51.4 Pseudopolyposis of colon	0.844	0.156	0.000
E78.5 Hyperlipidaemia, unspecified	0.000	0.158	0.842
Chapter VIII Diseases of the ear and mastoid process	0.000	0.158	0.842
M79.62 Pain in limb (Upper arm)	0.000	0.161	0.839
I25.9 Chronic ischaemic heart disease, unspecified	0.000	0.164	0.836
E74 Other disorders of carbohydrate metabolism	0.000	0.164	0.835
E13 Other specified diabetes mellitus	0.000	0.165	0.835
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.000	0.171	0.829
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.171	0.829
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.174	0.826
G37.9 Demyelinating disease of central nervous system, unspecified	0.821	0.179	0.000
I15 Secondary hypertension	0.000	0.181	0.819
M75.4 Impingement syndrome of shoulder	0.000	0.181	0.819
E11.1 With ketoacidosis	0.000	0.181	0.819
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.182	0.818
M79.67 Pain in limb (Ankle and foot)	0.000	0.183	0.816
E10.4 With neurological complications	0.000	0.185	0.815
K51.5 Mucosal proctocolitis	0.809	0.191	0.000
H60-H62 Diseases of external ear	0.000	0.191	0.809
I12.0 Hypertensive renal disease with renal failure	0.000	0.198	0.802
K57.1 Diverticular disease of small intestine without perforation or abscess	0.000	0.198	0.802
K57.8 Diverticular disease of intestine, part unspecified, with perforation and abscess	0.000	0.199	0.801
M07.3 Other psoriatic arthropathies	0.000	0.199	0.801
E10.0 With coma	0.000	0.201	0.799
E10.8 With unspecified complications	0.000	0.203	0.797
M79.64 Pain in limb (Hand)	0.000	0.204	0.796
M06.4 Inflammatory polyarthropathy	0.000	0.206	0.794
K60 Fissure and fistula of anal and rectal regions	0.000	0.206	0.794
K51.2 Ulcerative (chronic) proctitis	0.790	0.210	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.000	0.212	0.788
M79.18 Myalgia (Other)	0.000	0.212	0.788
H60 Otitis externa	0.000	0.215	0.785
M06.3 Rheumatoid nodule	0.000	0.217	0.783
I25.0 Atherosclerotic cardiovascular disease, so described	0.000	0.218	0.782
M49 Spondylopathies in diseases classified elsewhere	0.000	0.230	0.770
M79.60 Pain in limb (Multiple sites)	0.000	0.238	0.762
H65-H75 Diseases of middle ear and mastoid	0.000	0.241	0.759
K60.2 Anal fissure, unspecified	0.000	0.246	0.754
I24.8 Other forms of acute ischaemic heart disease	0.000	0.246	0.754
M70.4 Prepatellar bursitis	0.000	0.247	0.753
E11.2 With renal complications	0.000	0.248	0.752
E14.3 With ophthalmic complications	0.000	0.251	0.749
I25.3 Aneurysm of heart	0.000	0.252	0.748
M05 Seropositive rheumatoid arthritis	0.000	0.252	0.748
E10.6 With other specified complications	0.000	0.253	0.747
M75.2 Bicipital tendinitis	0.000	0.260	0.740
H60.9 Otitis externa, unspecified	0.000	0.263	0.737
E10.5 With peripheral circulatory complications	0.000	0.265	0.735
K60.0 Acute anal fissure	0.000	0.265	0.735
K57.9 Diverticular disease of intestine, part unspecified, without perforation or abscess	0.000	0.266	0.734
E40-E46 Malnutrition	0.000	0.269	0.730
L42 Pityriasis rosea	0.000	0.272	0.728
E11.6 With other specified complications	0.000	0.274	0.726
E74.3 Other disorders of intestinal carbohydrate absorption	0.000	0.276	0.724
M46 Other inflammatory spondylopathies	0.000	0.276	0.724
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.278	0.722
E78.1 Pure hyperglyceridaemia	0.000	0.280	0.720
E78.4 Other hyperlipidaemia	0.000	0.280	0.719
I11 Hypertensive heart disease	0.000	0.283	0.717
E13.9 Without complications	0.000	0.283	0.717
E10.7 With multiple complications	0.000	0.283	0.717
I25.6 Silent myocardial ischaemia	0.000	0.283	0.717
E12 Malnutrition-related diabetes mellitus	0.000	0.283	0.717
I23 Certain current complications following acute myocardial infarction	0.000	0.283	0.717
L40.4 Guttate psoriasis	0.000	0.283	0.717
L40.2 Acrodermatitis continua	0.000	0.283	0.717
L40.1 Generalised pustular psoriasis	0.000	0.283	0.717
E11.7 With multiple complications	0.000	0.283	0.716
E78.6 Lipoprotein deficiency	0.000	0.284	0.716
E78.3 Hyperchylomicronaemia	0.000	0.284	0.716
I13 Hypertensive heart and renal disease	0.000	0.287	0.713
M06.98 Rheumatoid arthritis, unspecified (Other)	0.000	0.287	0.713
K51.1 Ulcerative (chronic) ileocolitis	0.712	0.288	0.000
E14.8 With unspecified complications	0.000	0.289	0.711
E14.7 With multiple complications	0.000	0.289	0.711
E14.5 With peripheral circulatory complications	0.000	0.289	0.711
E14.2 Withrenal complications	0.000	0.289	0.711
E14.1 With ketoacidosis	0.000	0.289	0.711
E14.0 With coma	0.000	0.289	0.711
E79 Disorders of purine and pyrimidine metabolism	0.000	0.289	0.710
E77 Disorders of glycoprotein metabolism	0.000	0.289	0.710
E76 Disorders of glycosaminoglycan metabolism	0.000	0.289	0.710
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.289	0.710
E72 Other disorders of amino-acid metabolism	0.000	0.289	0.710
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.289	0.710
E70 Disorders of aromatic amino-acid metabolism	0.000	0.289	0.710
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.289	0.710
L44 Other papulosquamous disorders	0.000	0.290	0.710
L41 Parapsoriasis	0.000	0.290	0.710
L45 Papulosquamous disorders in diseases classified elsewhere	0.000	0.290	0.710
G37.8 Other specified demyelinating diseases of central nervous system	0.710	0.290	0.000
E16 Other disorders of pancreatic internal secretion	0.000	0.291	0.709
I21.X Presumed acute myicardial infaction (unconfirmed)	0.000	0.293	0.707
L43.8 Other lichen planus	0.000	0.293	0.707
M06.8 Other specified rheumatoid arthritis	0.000	0.295	0.705
M06.2 Rheumatoid bursitis	0.000	0.295	0.705
M06.1 Adult-onset Still's disease	0.000	0.295	0.705
E10.2 With renal complications	0.000	0.296	0.704
E14.6 With other specified complications	0.000	0.296	0.704
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.298	0.702
I22.8 Subsequent myocardial infarction of other sites	0.000	0.298	0.702
H71 Cholesteatoma of middle ear	0.000	0.298	0.702
K90.8 Other intestinal malabsorption	0.000	0.300	0.700
M79.63 Pain in limb (Forearm)	0.000	0.302	0.698
I21.0 Acute transmural myocardial infarction of anterior wall	0.000	0.302	0.698
E11.5 With peripheral circulatory complications	0.000	0.303	0.697
M70.6 Trochanteric bursitis	0.000	0.303	0.697
K90.9 Intestinal malabsorption, unspecified	0.000	0.306	0.694
H74 Other disorders of middle ear and mastoid	0.000	0.306	0.694
M09 Juvenile arthritis in diseases classified elsewhere	0.000	0.307	0.693
M08 Juvenile arthritis	0.000	0.307	0.693
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.000	0.307	0.692
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.000	0.307	0.693
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.000	0.308	0.692
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.000	0.308	0.692
M45.X6 Ankylosing spondylitis (Lumbar region)	0.000	0.308	0.692
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.000	0.308	0.692
M45.X4 Ankylosing spondylitis (Thoracic region)	0.000	0.308	0.692
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.000	0.308	0.692
M45.X2 Ankylosing spondylitis (Cervical region)	0.000	0.308	0.692
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.000	0.308	0.692
M07.39 Other psoriatic arthropathies (Site unspecified)	0.000	0.310	0.690
L43.3 Subacute (active) lichen planus	0.000	0.312	0.688
L43.2 Lichenoid drug reaction	0.000	0.312	0.688
L43.1 Bullous lichen planus	0.000	0.312	0.688
L43.0 Hypertrophic lichen planus	0.000	0.312	0.688
M70.46 Prepatellar bursitis-Lower Leg	0.000	0.312	0.688
M73 Soft tissue disorders in diseases classified elsewhere	0.000	0.314	0.686
Chapter XVI Certain conditions originating in the perinatal period	0.000	0.316	0.684
M79.9 Soft tissue disorder, unspecified	0.000	0.317	0.683
E84 Cystic fibrosis	0.000	0.320	0.680
M79.3 Panniculitis, unspecified	0.000	0.322	0.678
K57.5 Diverticular disease of both small and large intestine without perforation or abscess	0.000	0.322	0.678
I20.0 Unstable angina	0.000	0.326	0.674
K90.3 Pancreatic steatorrhoea	0.000	0.326	0.673
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.326	0.673
K90.1 Tropical sprue	0.000	0.326	0.673
E11.4 With neurological complications	0.000	0.331	0.669
K51.0 Ulcerative (chronic) enterocolitis	0.669	0.331	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.000	0.332	0.668
I22.0 Subsequent myocardial infarction of anterior wall	0.000	0.332	0.667
M77 Other enthesopathies	0.000	0.335	0.665
E89.3 Postprocedural hypopituitarism	0.000	0.336	0.664
H60.3 Other infective otitis externa	0.000	0.336	0.664
M11 Other crystal arthropathies	0.000	0.340	0.660
M75.8 Other shoulder lesions	0.000	0.341	0.659
M79.4 Hypertrophy of (infrapatellar) fat pad	0.000	0.341	0.659
I15.9 Seconday hypertension, unspecified	0.000	0.342	0.658
E14.4 With neurological complications	0.000	0.344	0.656
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.345	0.655
E85 Amyloidosis	0.000	0.352	0.648
G36 Other acute disseminated demyelination	0.646	0.354	0.000
H73 Other disorders of tympanic membrane	0.000	0.354	0.646
I00-I02 Acute rheumatic fever	0.000	0.354	0.646
M07.36 Other psoriatic arthropathies (Lower leg)	0.000	0.355	0.645
M06.34 Rheumatoid nodule (Hand)	0.000	0.357	0.643
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.642	0.358	0.000
I15.1 Hypertension secondary to other renal disorders	0.000	0.360	0.639
M79.15 Myalgia (Pelvic region and thigh)	0.000	0.361	0.639
K93 Disorders of other digestive organs in diseases classified elsewhere	0.000	0.362	0.638
M79.78 Fibromyalgia (Other)	0.000	0.362	0.638
M79.77 Fibromyalgia (Ankle and foot)	0.000	0.362	0.638
M79.76 Fibromyalgia (Lower leg)	0.000	0.362	0.638
M79.75 Fibromyalgia (Pelvic region and thigh)	0.000	0.362	0.638
M79.74 Fibromyalgia (Hand)	0.000	0.362	0.638
M79.73 Fibromyalgia (Forearm)	0.000	0.362	0.638
M79.72 Fibromyalgia (Upper arm)	0.000	0.362	0.638
M79.71 Fibromyalgia (Shoulder region)	0.000	0.362	0.638
M79.61 Pain in limb (Shoulder region)	0.000	0.364	0.636
H74.8 Other specified disorders of middle ear and mastoid	0.000	0.364	0.636
I20.1 Angina pectoris with documented spasm	0.000	0.365	0.635
K57.4 Diverticular disease of both small and large intestine with perforation and abscess	0.000	0.365	0.635
K64 Haemorrhoids and perianal venous thrombosis	0.000	0.365	0.634
E20-E35 Disorders of other endocrine glands	0.000	0.366	0.634
M49.5 Collapsed vertebra in diseases classified elsewhere	0.000	0.367	0.633
M05.9 Seropositive rheumatoid arthritis, unspecified	0.000	0.367	0.633
H61 Other disorders of external ear	0.000	0.367	0.633
L40.3 Pustulosis palmaris et plantaris	0.000	0.368	0.632
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.000	0.370	0.630
M91-M94 Chondropathies	0.000	0.370	0.630
I24.1 Dressler's syndrome	0.000	0.373	0.627
M79.68 Pain in limb (Other)	0.000	0.373	0.627
E83 Disorders of mineral metabolism	0.339	0.374	0.287
M46.4 Discitis, unspecified	0.000	0.375	0.625
M79.16 Myalgia (Lower leg)	0.000	0.376	0.624
G37.5 Concentric sclerosis [Balo]	0.620	0.380	0.000
G37.4 Subacute necrotising myelitis	0.620	0.380	0.000
G37.2 Central pontine myelinolysis	0.620	0.380	0.000
G37.1 Central demyelination of corpus callosum	0.620	0.380	0.000
G37.0 Diffuse sclerosis	0.620	0.380	0.000
M14 Arthropathies in other diseases classified elsewhere	0.000	0.380	0.620
M12 Other specific arthropathies	0.000	0.380	0.619
M07.5 Arthropathy in ulcerative colitis	0.000	0.382	0.618
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.000	0.382	0.618
M07.2 Psoriatic spondylitis	0.000	0.382	0.618
M07.1 Arthritis mutilans	0.000	0.382	0.618
M07.0 Distal interphalangeal psoriatic arthropathy	0.000	0.382	0.618
H60.8 Other otitis externa	0.000	0.387	0.613
I22.9 Subsequent myocardial infarction of unspecified site	0.000	0.387	0.613
M79.17 Myalgia (Ankle and foot)	0.000	0.389	0.611
M79.14 Myalgia (Hand)	0.000	0.389	0.611
M79.13 Myalgia (Forearm)	0.000	0.389	0.611
M79.12 Myalgia (Upper arm)	0.000	0.389	0.611
I25.4 Coronary artery aneurysm	0.000	0.389	0.610
M79.11 Myalgia (Shoulder region)	0.000	0.390	0.610
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.000	0.391	0.609
H60.1 Cellulitis of external ear	0.000	0.394	0.606
M70.9 Unspecified soft tissue disorder related to use, overuse and pressure	0.000	0.394	0.606
M70.8 Other soft tissue disorders related to use, overuse and pressure	0.000	0.394	0.606
M70.5 Other bursitis of knee	0.000	0.394	0.606
M70.1 Bursitis of hand	0.000	0.394	0.606
M70.0 Chronic crepitant synovitis of hand and wrist	0.000	0.394	0.606
E16.2 Hypoglycaemia, unspecified	0.000	0.395	0.605
K59 Other functional intestinal disorders	0.000	0.396	0.604
K57.0 Diverticular disease of small intestine with perforation and abscess	0.000	0.401	0.599
E74.9 Disorder of carbohydrate metabolism, unspecified	0.000	0.401	0.599
E74.8 Other specified disorders of carbohydrate metabolism	0.000	0.401	0.599
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.000	0.401	0.599
E74.2 Disorders of galactose metabolism	0.000	0.401	0.599
E74.1 Disorders of fructose metabolism	0.000	0.401	0.599
E74.0 Glycogen storage disease	0.000	0.401	0.599
E13.8 With unspecified complications	0.000	0.401	0.599
E13.7 With multiple complications	0.000	0.401	0.599
E13.6 With other specified complications	0.000	0.401	0.599
E13.5 With peripheral circulatory complications	0.000	0.401	0.599
E13.4 With neurological complications	0.000	0.401	0.599
E13.3 With ophthalmic complications	0.000	0.401	0.599
E13.2 With renal complications	0.000	0.401	0.599
E13.1 With ketoacidosis	0.000	0.401	0.599
E13.0 With coma	0.000	0.401	0.599
E15 Nondiabetic hypoglycaemic coma	0.000	0.406	0.594
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.000	0.408	0.592
M70.7 Other bursitis of hip	0.000	0.408	0.592
M70.65 Trochanteric bursitis-Pelvic/Thigh	0.000	0.409	0.591
I21.3 Acute transmural myocardial infarction of unspecified site	0.000	0.410	0.590
I15.8 Other secondary hypertension	0.000	0.412	0.587
I15.2 Hypertension secondary to endocrine disorders	0.000	0.412	0.587
I15.0 Renovascular hypertension	0.000	0.412	0.587
H74.4 Polyp of middle ear	0.000	0.413	0.587
K60.5 Anorectal fistula	0.000	0.414	0.586
M79.19 Myalgia (Site unspecified)	0.000	0.416	0.584
H60.5 Acute otitis externa, non-infective	0.000	0.420	0.580
M79.10 Myalgia (Multiple sites)	0.000	0.422	0.578
H61.1 Non-infective disorders of pinna	0.000	0.422	0.578
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.424	0.576
L50-L54 Urticaria and erythema	0.000	0.425	0.575
M07.38 Other psoriatic arthropathies (Other)	0.000	0.426	0.574
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.000	0.426	0.574
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.000	0.426	0.574
M07.34 Other psoriatic arthropathies (Hand)	0.000	0.426	0.574
M07.33 Other psoriatic arthropathies (Forearm)	0.000	0.426	0.574
M07.32 Other psoriatic arthropathies (Upper arm)	0.000	0.426	0.574
M07.31 Other psoriatic arthropathies (Shoulder region)	0.000	0.426	0.574
L10-L14 Bullous disorders	0.000	0.427	0.573
M70.2 Olecranon bursitis	0.000	0.429	0.571
M79.69 Pain in limb (Site unspecified)	0.000	0.429	0.571
M06.48 Inflammatory polyarthropathy (Other)	0.000	0.430	0.569
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.000	0.430	0.569
M06.46 Inflammatory polyarthropathy (Lower leg)	0.000	0.430	0.569
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.000	0.430	0.569
M06.44 Inflammatory polyarthropathy (Hand)	0.000	0.430	0.569
M06.43 Inflammatory polyarthropathy (Forearm)	0.000	0.430	0.569
M06.42 Inflammatory polyarthropathy (Upper arm)	0.000	0.430	0.569
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.000	0.430	0.569
H60.4 Cholesteatoma of external ear	0.000	0.431	0.569
M77.1 Lateral epicondylitis	0.000	0.432	0.568
M07.6 Other enteropathic arthropathies	0.000	0.432	0.567
M06.0 Seronegative rheumatoid arthritis	0.000	0.433	0.567
M70.3 Other bursitis of elbow	0.000	0.434	0.566
H73.8 Other specified disorders of tympanic membrane	0.000	0.435	0.565
H60.2 Malignant otitis externa	0.000	0.437	0.563
H66 Suppurative and unspecified otitis media	0.000	0.438	0.562
M06.39 Rheumatoid nodule (Site unspecified)	0.000	0.439	0.561
M06.38 Rheumatoid nodule (Other)	0.000	0.439	0.561
M06.36 Rheumatoid nodule (Lower leg)	0.000	0.439	0.561
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.000	0.439	0.561
M06.33 Rheumatoid nodule (Forearm)	0.000	0.439	0.561
M06.32 Rheumatoid nodule (Upper arm)	0.000	0.439	0.561
M06.31 Rheumatoid nodule (Shoulder region)	0.000	0.439	0.561
M06.30 Rheumatoid nodule (Multiple sites)	0.000	0.439	0.561
M06.37 Rheumatoid nodule (Ankle and foot)	0.000	0.445	0.555
E11.8 With unspecified complications	0.000	0.445	0.555
M46.46 Discitis, unspecified (Lumbar region)	0.000	0.445	0.555
E73 Lactose intolerance	0.001	0.448	0.552
E28 Ovarian dysfunction	0.000	0.448	0.552
M49.8 Spondylopathy in other diseases classified elsewhere	0.000	0.448	0.552
M49.4 Neuropathic spondylopathy	0.000	0.448	0.552
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere	0.000	0.448	0.552
M49.2 Enterobacterial spondylitis	0.000	0.448	0.552
M49.1 Brucella spondylitis	0.000	0.448	0.552
M49.0 Tuberculosis of spine	0.000	0.448	0.552
M96.0 Pseudarthrosis after fusion or arthrodesis	0.000	0.448	0.552
M79.5 Residual foreign body in soft tissue	0.000	0.449	0.551
H74.9 Disorder of middle ear and mastoid, unspecified	0.000	0.451	0.549
M49.54 Collapsed vertebra in diseases classified elsewhere (Thoracic region)	0.000	0.451	0.548
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.456	0.544
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.000	0.456	0.544
H68 Eustachian salpingitis and obstruction	0.000	0.456	0.544
H67 Otitis media in diseases classified elsewhere	0.000	0.456	0.544
E46 Unspecified protein-energy malnutrition	0.000	0.460	0.540
M70.49 Prepatellar bursitis-Site unspec	0.000	0.460	0.540
M70.48 Prepatellar bursitis-Other	0.000	0.460	0.540
M70.47 Prepatellar bursitis-Ankle/Foot	0.000	0.460	0.540
M70.45 Prepatellar bursitis-Pelvic/Thigh	0.000	0.460	0.540
M70.44 Prepatellar bursitis-Hand	0.000	0.460	0.540
M70.43 Prepatellar bursitis-Forearm	0.000	0.460	0.540
M70.42 Prepatellar bursitis-Upper arm	0.000	0.460	0.540
M70.41 Prepatellar bursitis-Shldr region	0.000	0.460	0.540
M70.40 Prepatellar bursitis-Mult sites	0.000	0.460	0.540
M05.8 Other seropositive rheumatoid arthritis	0.000	0.463	0.536
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.000	0.463	0.536
M05.1 Rheumatoid lung disease	0.000	0.463	0.536
M05.0 Felty's syndrome	0.000	0.463	0.536
M65-M68 Disorders of synovium and tendon	0.000	0.464	0.536
M75.9 Shoulder lesion, unspecified	0.000	0.465	0.534
H62 Disorders of external ear in diseases classified elsewhere	0.000	0.469	0.531
M72 Fibroblastic disorders	0.000	0.472	0.528
K70-K77 Diseases of liver	0.000	0.474	0.526
E80 Disorders of porphyrin and bilirubin metabolism	0.000	0.475	0.525
H66.3 Other chronic suppurative otitis media	0.000	0.475	0.525
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.476	0.524
E45 Retarded development following protein-energy malnutrition	0.000	0.476	0.524
E43 Unspecified severe protein-energy malnutrition	0.000	0.476	0.524
E42 Marasmic kwashiorkor	0.000	0.476	0.524
E41 Nutritional marasmus	0.000	0.476	0.524
E40 Kwashiorkor	0.000	0.476	0.524
M79.70 Fibromyalgia (Multiple sites)	0.000	0.477	0.523
M75.3 Calcific tendinitis of shoulder	0.000	0.478	0.522
M80-M85 Disorders of bone density and structure	0.000	0.478	0.522
M00-M03 Infectious arthropathies	0.000	0.478	0.521
E00-E07 Disorders of thyroid gland	0.000	0.478	0.522
I11.0 Hypertensive heart disease with (congestive) heart failure	0.000	0.480	0.520
M46.8 Other specified inflammatory spondylopathies	0.000	0.481	0.519
M46.5 Other infective spondylopathies	0.000	0.481	0.519
M46.2 Osteomyelitis of vertebra	0.000	0.481	0.519
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.000	0.482	0.517
E89.8 Other postprocedural endocrine and metabolic disorders	0.000	0.482	0.517
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.000	0.482	0.517
E89.5 Postprocedural testicular hypofunction	0.000	0.482	0.517
E89.4 Postprocedural ovarian failure	0.000	0.482	0.517
E89.1 Postprocedural hypoinsulinaemia	0.000	0.482	0.517
M77.4 Metatarsalgia	0.000	0.483	0.517
K59.9 Functional intestinal disorder, unspecified	0.000	0.484	0.516
E28.2 Polycystic ovarian syndrome	0.000	0.484	0.516
E23 Hypofunction and other disorders of pituitary gland	0.000	0.485	0.515
E12.9 Without complications	0.000	0.486	0.514
E12.8 With unspecified complications	0.000	0.486	0.514
E12.7 With multiple complications	0.000	0.486	0.514
E12.6 With other specified complications	0.000	0.486	0.514
E12.5 With peripheral circulatory complications	0.000	0.486	0.514
E12.4 With neurological complications	0.000	0.486	0.514
E12.3 With ophthalmic complications	0.000	0.486	0.514
E12.2 With renal complications	0.000	0.486	0.514
E12.1 With ketoacidosis	0.000	0.486	0.514
E12.0 With coma	0.000	0.486	0.514
I23.8 Other current complications following acute myocardial infarction	0.000	0.486	0.514
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.000	0.486	0.514
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.000	0.486	0.514
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.000	0.486	0.514
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.000	0.486	0.514
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.000	0.486	0.514
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.000	0.486	0.514
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.000	0.486	0.514
E24 Cushing's syndrome	0.000	0.486	0.514
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.486	0.514
H61.3 Acquired stenosis of external ear canal	0.000	0.486	0.514
I13.9 Hypertensive heart and renal disease, unspecified	0.000	0.489	0.511
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.000	0.489	0.511
I13.1 Hypertensive heart and renal disease with renal failure	0.000	0.489	0.511
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.000	0.489	0.511
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.000	0.490	0.509
E70.8 Other disorders of aromatic amino-acid metabolism	0.000	0.490	0.509
E70.3 Albinism	0.000	0.490	0.509
E70.2 Disorders of tyrosine metabolism	0.000	0.490	0.509
E70.1 Other hyperphenylalaninaemias	0.000	0.490	0.509
E70.0 Classical phenylketonuria	0.000	0.490	0.509
E71.3 Disorders of fatty-acid metabolism	0.000	0.490	0.509
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.000	0.490	0.509
E71.1 Other disorders of branched-chain amino-acid metabolism	0.000	0.490	0.509
E71.0 Maple-syrup-urine disease	0.000	0.490	0.509
E72.9 Disorder of amino-acid metabolism, unspecified	0.000	0.490	0.509
E72.8 Other specified disorders of amino-acid metabolism	0.000	0.490	0.509
E72.5 Disorders of glycine metabolism	0.000	0.490	0.509
E72.4 Disorders of ornithine metabolism	0.000	0.490	0.509
E72.3 Disorders of lysine and hydroxylysine metabolism	0.000	0.490	0.509
E72.2 Disorders of urea cycle metabolism	0.000	0.490	0.509
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.000	0.490	0.509
E72.0 Disorders of amino-acid transport	0.000	0.490	0.509
E75.6 Lipid storage disorder, unspecified	0.000	0.490	0.509
E75.5 Other lipid storage disorders	0.000	0.490	0.509
E75.4 Neuronal ceroid lipofuscinosis	0.000	0.490	0.509
E75.3 Sphingolipidosis, unspecified	0.000	0.490	0.509
E75.2 Other sphingolipidosis	0.000	0.490	0.509
E75.1 Other gangliosidosis	0.000	0.490	0.509
E75.0 GM2 gangliosidosis	0.000	0.490	0.509
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.000	0.490	0.509
E76.8 Other disorders of glucosaminoglycan metabolism	0.000	0.490	0.509
E76.3 Mucopolysaccharidosis, unspecified	0.000	0.490	0.509
E76.2 Other mucopolysaccharidoses	0.000	0.490	0.509
E76.1 Mucopolysaccharidosis, type II	0.000	0.490	0.509
E76.0 Mucopolysaccharidosis, type I	0.000	0.490	0.509
E77.9 Disorder of glycoprotein metabolism, unspecified	0.000	0.490	0.509
E77.8 Other disorders of glycoprotein metabolism	0.000	0.490	0.509
E77.1 Defects in glycoprotein degradation	0.000	0.490	0.509
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.000	0.490	0.509
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.000	0.490	0.509
E79.8 Other disorders of purine and pyrimidine metabolism	0.000	0.490	0.509
E79.1 Lesch-Nyhan syndrome	0.000	0.490	0.509
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.000	0.490	0.509
L41.9 Parapsoriasis, unspecified	0.000	0.490	0.509
L41.8 Other parapsoriasis	0.000	0.490	0.509
L41.5 Retiform parapsoriasis	0.000	0.490	0.509

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations