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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3094682
log Bayes Factor = 62.0263
Chromosome 6   position 31,264,461  (GRCh37) Explore rs3094682 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
E11.9 Without complications
0.000 0.000 1.000
E78.0 Pure hypercholesterolaemia
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
E03 Other hypothyroidism
0.000 0.000 1.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.001 0.999
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.002 0.998
E10.3 With ophthalmic complications
0.000 0.003 0.997
E70-E90 Metabolic disorders
0.000 0.003 0.997
E05.9 Thyrotoxicosis, unspecified
0.000 0.004 0.996
I25 Chronic ischaemic heart disease
0.000 0.007 0.993
I25.1 Atherosclerotic heart disease
0.000 0.008 0.992
E14 Unspecified diabetes mellitus
0.000 0.013 0.987
I25.2 Old myocardial infarction
0.000 0.015 0.985
M06.9 Rheumatoid arthritis, unspecified
0.000 0.017 0.983
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.020 0.980
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.025 0.975
L40 Psoriasis
0.000 0.026 0.974
E14.9 Without complications
0.000 0.030 0.970
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.036 0.964
M45.X9 Ankylosing spondylitis (Site unspecified)
0.955 0.045 0.000
L40.5 Arthropathic psoriasis
0.000 0.049 0.951
E11.0 With coma
0.000 0.057 0.943
I20-I25 Ischaemic heart diseases
0.000 0.060 0.940
E10.1 With ketoacidosis
0.000 0.062 0.938
E11.1 With ketoacidosis
0.000 0.063 0.937
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.071 0.929
E78.2 Mixed hyperlipidaemia
0.000 0.073 0.927
I22 Subsequent myocardial infarction
0.000 0.095 0.905
E07 Other disorders of thyroid
0.000 0.114 0.886
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.114 0.886
E10.4 With neurological complications
0.000 0.123 0.877
E78.8 Other disorders of lipoprotein metabolism
0.000 0.124 0.876
I24 Other acute ischaemic heart diseases
0.000 0.125 0.875
M45 Ankylosing spondylitis
0.874 0.126 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.133 0.867
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.134 0.866
E74 Other disorders of carbohydrate metabolism
0.000 0.146 0.854
E40-E46 Malnutrition
0.000 0.154 0.846
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.156 0.844
I25.5 Ischaemic cardiomyopathy
0.000 0.159 0.841
E13 Other specified diabetes mellitus
0.000 0.163 0.837
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.832 0.168 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.169 0.831
E10.0 With coma
0.000 0.181 0.819
E14.3 With ophthalmic complications
0.000 0.184 0.816
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.185 0.814
E07.9 Disorder of thyroid, unspecified
0.000 0.186 0.814
L40.0 Psoriasis vulgaris
0.000 0.188 0.812
E03.8 Other specified hypothyroidism
0.000 0.193 0.807
E10.2 With renal complications
0.000 0.193 0.807
I25.3 Aneurysm of heart
0.000 0.194 0.806
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.200 0.800
E10.8 With unspecified complications
0.000 0.204 0.796
E20-E35 Disorders of other endocrine glands
0.000 0.205 0.795
E78.1 Pure hyperglyceridaemia
0.000 0.205 0.795
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.230 0.770
E10.6 With other specified complications
0.000 0.233 0.767
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.238 0.762
E11.5 With peripheral circulatory complications
0.000 0.239 0.761
K90 Intestinal malabsorption
0.000 0.244 0.756
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.248 0.752
L40.8 Other psoriasis
0.000 0.249 0.751
I20 Angina pectoris
0.000 0.253 0.747
E78.4 Other hyperlipidaemia
0.000 0.255 0.745
M45.X2 Ankylosing spondylitis (Cervical region)
0.745 0.255 0.000
E78.6 Lipoprotein deficiency
0.000 0.256 0.744
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.261 0.739
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.262 0.738
E46 Unspecified protein-energy malnutrition
0.000 0.265 0.735
I23 Certain current complications following acute myocardial infarction
0.000 0.269 0.731
E79 Disorders of purine and pyrimidine metabolism
0.000 0.273 0.727
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.273 0.727
E14.8 With unspecified complications
0.000 0.275 0.725
E28 Ovarian dysfunction
0.000 0.275 0.725
E14.4 With neurological complications
0.000 0.280 0.720
E13.9 Without complications
0.000 0.280 0.720
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.281 0.719
I20.9 Angina pectoris, unspecified
0.000 0.282 0.718
E05.8 Other thyrotoxicosis
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E78.3 Hyperchylomicronaemia
0.000 0.283 0.716
E11.6 With other specified complications
0.000 0.284 0.716
E05.5 Thyroid crisis or storm
0.000 0.284 0.715
E05.4 Thyrotoxicosis factitia
0.000 0.284 0.715
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.284 0.715
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.284 0.715
E84 Cystic fibrosis
0.000 0.285 0.715
E77 Disorders of glycoprotein metabolism
0.000 0.285 0.715
E76 Disorders of glycosaminoglycan metabolism
0.000 0.285 0.715
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.285 0.715
E72 Other disorders of amino-acid metabolism
0.000 0.285 0.715
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.285 0.715
E70 Disorders of aromatic amino-acid metabolism
0.000 0.285 0.715
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.285 0.715
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.286 0.714
I25.6 Silent myocardial ischaemia
0.000 0.288 0.712
E14.7 With multiple complications
0.000 0.292 0.707
E14.6 With other specified complications
0.000 0.292 0.707
E14.5 With peripheral circulatory complications
0.000 0.292 0.707
E14.2 Withrenal complications
0.000 0.292 0.707
E14.1 With ketoacidosis
0.000 0.292 0.707
E14.0 With coma
0.000 0.292 0.707
E11.2 With renal complications
0.000 0.293 0.707
E78.5 Hyperlipidaemia, unspecified
0.000 0.302 0.698
L40.4 Guttate psoriasis
0.000 0.302 0.698
L40.2 Acrodermatitis continua
0.000 0.302 0.698
L40.1 Generalised pustular psoriasis
0.000 0.302 0.698
E28.2 Polycystic ovarian syndrome
0.000 0.312 0.688
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.318 0.682
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.324 0.676
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.328 0.672
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.334 0.666
K90.9 Intestinal malabsorption, unspecified
0.000 0.337 0.663
M45.X6 Ankylosing spondylitis (Lumbar region)
0.661 0.339 0.000
E23 Hypofunction and other disorders of pituitary gland
0.000 0.343 0.657
E16 Other disorders of pancreatic internal secretion
0.000 0.343 0.657
E50-E64 Other nutritional deficiencies
0.000 0.358 0.642
E07.1 Dyshormogenetic goitre
0.000 0.365 0.635
E07.0 Hypersecretion of calcitonin
0.000 0.365 0.635
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.366 0.634
E73 Lactose intolerance
0.000 0.366 0.634
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.626 0.374 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.626 0.374 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.626 0.374 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.626 0.374 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.626 0.374 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.626 0.374 0.000
E10.5 With peripheral circulatory complications
0.000 0.374 0.626
G35-G37 Demyelinating diseases of the central nervous system
0.620 0.380 0.000
E24 Cushing's syndrome
0.000 0.384 0.616
L40-L45 Papulosquamous disorders
0.000 0.385 0.615
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.386 0.614
E11.8 With unspecified complications
0.000 0.387 0.613
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.387 0.612
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.387 0.612
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.387 0.612
E74.2 Disorders of galactose metabolism
0.000 0.387 0.612
E74.1 Disorders of fructose metabolism
0.000 0.387 0.612
E74.0 Glycogen storage disease
0.000 0.387 0.612
E21.3 Hyperparathyroidism, unspecified
0.000 0.393 0.607
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.394 0.606
E45 Retarded development following protein-energy malnutrition
0.000 0.394 0.606
E43 Unspecified severe protein-energy malnutrition
0.000 0.394 0.606
E42 Marasmic kwashiorkor
0.000 0.394 0.606
E41 Nutritional marasmus
0.000 0.394 0.606
E40 Kwashiorkor
0.000 0.394 0.606
E07.8 Other specified disorders of thyroid
0.000 0.399 0.601
E13.8 With unspecified complications
0.000 0.400 0.600
E13.7 With multiple complications
0.000 0.400 0.600
E13.6 With other specified complications
0.000 0.400 0.600
E13.5 With peripheral circulatory complications
0.000 0.400 0.600
E13.4 With neurological complications
0.000 0.400 0.600
E13.3 With ophthalmic complications
0.000 0.400 0.600
E13.2 With renal complications
0.000 0.400 0.600
E13.1 With ketoacidosis
0.000 0.400 0.600
E13.0 With coma
0.000 0.400 0.600
I22.8 Subsequent myocardial infarction of other sites
0.000 0.400 0.600
L40.3 Pustulosis palmaris et plantaris
0.000 0.404 0.596
E06 Thyroiditis
0.000 0.406 0.594
I24.1 Dressler's syndrome
0.000 0.408 0.592
E85 Amyloidosis
0.000 0.409 0.590
I23.8 Other current complications following acute myocardial infarction
0.000 0.418 0.582
E83 Disorders of mineral metabolism
0.451 0.423 0.126
E88 Other metabolic disorders
0.000 0.424 0.576
E15 Nondiabetic hypoglycaemic coma
0.000 0.426 0.574
K90.8 Other intestinal malabsorption
0.000 0.428 0.572
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.430 0.570
E32 Diseases of thymus
0.000 0.430 0.570
E31 Polyglandular dysfunction
0.000 0.430 0.570
E30 Disorders of puberty, not elsewhere classified
0.000 0.430 0.570
E25 Adrenogenital disorders
0.000 0.430 0.570
E61 Deficiency of other nutrient elements
0.000 0.430 0.569
E89.3 Postprocedural hypopituitarism
0.000 0.432 0.568
E11.4 With neurological complications
0.000 0.434 0.566
E16.1 Other hypoglycaemia
0.000 0.449 0.551
E23.7 Disorder of pituitary gland, unspecified
0.000 0.452 0.548
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.454 0.546
K90.3 Pancreatic steatorrhoea
0.000 0.458 0.542
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.458 0.542
K90.1 Tropical sprue
0.000 0.458 0.542
I24.8 Other forms of acute ischaemic heart disease
0.000 0.458 0.541
E23.2 Diabetes insipidus
0.000 0.463 0.537
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.466 0.534
L43 Lichen planus
0.000 0.467 0.533
G37 Other demyelinating diseases of central nervous system
0.532 0.468 0.000
E22 Hyperfunction of pituitary gland
0.000 0.469 0.530
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.476 0.524
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.476 0.524
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.476 0.524
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.476 0.524
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.476 0.524
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.476 0.524
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.476 0.524
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.479 0.521
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.479 0.521
E79.1 Lesch-Nyhan syndrome
0.000 0.479 0.521
E28.9 Ovarian dysfunction, unspecified
0.000 0.480 0.520
E28.8 Other ovarian dysfunction
0.000 0.480 0.520
E28.1 Androgen excess
0.000 0.480 0.520
E28.0 Oestrogen excess
0.000 0.480 0.520
E61.1 Iron deficiency
0.000 0.484 0.516
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E80.6 Other disorders of bilirubin metabolism
0.000 0.487 0.513
E29 Testicular dysfunction
0.000 0.487 0.512
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.487 0.512
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.487 0.512
E70.3 Albinism
0.000 0.487 0.512
E70.2 Disorders of tyrosine metabolism
0.000 0.487 0.512
E70.1 Other hyperphenylalaninaemias
0.000 0.487 0.512
E70.0 Classical phenylketonuria
0.000 0.487 0.512
E71.3 Disorders of fatty-acid metabolism
0.000 0.487 0.512
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.487 0.512
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.487 0.512
E71.0 Maple-syrup-urine disease
0.000 0.487 0.512
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.487 0.512
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.487 0.512
E72.5 Disorders of glycine metabolism
0.000 0.487 0.512
E72.4 Disorders of ornithine metabolism
0.000 0.487 0.512
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.487 0.512
E72.2 Disorders of urea cycle metabolism
0.000 0.487 0.512
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.487 0.512
E72.0 Disorders of amino-acid transport
0.000 0.487 0.512
E75.6 Lipid storage disorder, unspecified
0.000 0.487 0.512
E75.5 Other lipid storage disorders
0.000 0.487 0.512
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.487 0.512
E75.3 Sphingolipidosis, unspecified
0.000 0.487 0.512
E75.2 Other sphingolipidosis
0.000 0.487 0.512
E75.1 Other gangliosidosis
0.000 0.487 0.512
E75.0 GM2 gangliosidosis
0.000 0.487 0.512
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.487 0.512
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.487 0.512
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.487 0.512
E76.2 Other mucopolysaccharidoses
0.000 0.487 0.512
E76.1 Mucopolysaccharidosis, type II
0.000 0.487 0.512
E76.0 Mucopolysaccharidosis, type I
0.000 0.487 0.512
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.487 0.512
E77.8 Other disorders of glycoprotein metabolism
0.000 0.487 0.512
E77.1 Defects in glycoprotein degradation
0.000 0.487 0.512
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.487 0.512
E84.9 Cystic fibrosis, unspecified
0.000 0.487 0.512
E84.8 Cystic fibrosis with other manifestations
0.000 0.487 0.512
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.487 0.512
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.487 0.512
M06 Other rheumatoid arthritis
0.001 0.488 0.511
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.489 0.511
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.491 0.509
E26 Hyperaldosteronism
0.000 0.492 0.508
I25.4 Coronary artery aneurysm
0.000 0.493 0.506
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.503 0.497
E16.2 Hypoglycaemia, unspecified
0.000 0.506 0.494
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.511 0.489
E21.4 Other specified disorders of parathyroid gland
0.000 0.511 0.489
E21.2 Other hyperparathyroidism
0.000 0.511 0.489
E89.4 Postprocedural ovarian failure
0.000 0.512 0.488
E89.2 Postprocedural hypoparathyroidism
0.000 0.512 0.488
I20.0 Unstable angina
0.000 0.513 0.487
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.515 0.485
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.515 0.485
E89.5 Postprocedural testicular hypofunction
0.000 0.515 0.485
E89.1 Postprocedural hypoinsulinaemia
0.000 0.515 0.485
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.518 0.482
E80.5 Crigler-Najjar syndrome
0.000 0.518 0.482
E80.3 Defects of catalase and peroxydase
0.000 0.518 0.482
E80.2 Other porphyria
0.000 0.518 0.482
E80.1 Porphyria cutanea tarda
0.000 0.518 0.482
E80.0 Hereditary erythropoietic porphyria
0.000 0.518 0.482
E24.2 Drug-induced Cushing's syndrome
0.000 0.524 0.476
L43.9 Lichen planus, unspecified
0.000 0.527 0.472
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.529 0.471
E23.1 Drug-induced hypopituitarism
0.000 0.529 0.471
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.529 0.471
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.529 0.471
E16.4 Abnormal secretion of gastrin
0.000 0.529 0.471
E16.3 Increased secretion of glucagon
0.000 0.529 0.471
E23.6 Other disorders of pituitary gland
0.000 0.531 0.469
E88.2 Lipomatosis, not elsewhere classified
0.000 0.538 0.461
L42 Pityriasis rosea
0.000 0.539 0.461
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.540 0.460
E63 Other nutritional deficiencies
0.000 0.540 0.460
E56 Other vitamin deficiencies
0.000 0.540 0.460
E51 Thiamine deficiency
0.000 0.540 0.460
E50 Vitamin A deficiency
0.000 0.540 0.460
E60 Dietary zinc deficiency
0.000 0.540 0.460
E59 Dietary selenium deficiency
0.000 0.540 0.460
E54 Ascorbic acid deficiency
0.000 0.540 0.460
E52 Niacin deficiency [pellagra]
0.000 0.540 0.460
E21.0 Primary hyperparathyroidism
0.000 0.540 0.460
E24.9 Cushing's syndrome, unspecified
0.000 0.545 0.455
E73.8 Other lactose intolerance
0.000 0.545 0.454
E73.1 Secondary lactase deficiency
0.000 0.545 0.454
E73.0 Congenital lactase deficiency
0.000 0.545 0.454
M06.3 Rheumatoid nodule
0.000 0.546 0.453
G37.9 Demyelinating disease of central nervous system, unspecified
0.453 0.547 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.550 0.450
E20 Hypoparathyroidism
0.000 0.551 0.449
E28.3 Primary ovarian failure
0.000 0.552 0.448
E58 Dietary calcium deficiency
0.000 0.555 0.445
G36 Other acute disseminated demyelination
0.444 0.556 0.000
E85.9 Amyloidosis, unspecified
0.000 0.558 0.441
E24.8 Other Cushing's syndrome
0.000 0.558 0.441
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.558 0.441
E24.3 Ectopic ACTH syndrome
0.000 0.558 0.441
E24.1 Nelson's syndrome
0.000 0.558 0.441
E24.0 Pituitary-dependent Cushing's disease
0.000 0.558 0.441
L44 Other papulosquamous disorders
0.000 0.559 0.441
L41 Parapsoriasis
0.000 0.559 0.441
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.559 0.441
E34 Other endocrine disorders
0.000 0.562 0.438
I20.1 Angina pectoris with documented spasm
0.000 0.562 0.438
E44.1 Mild protein-energy malnutrition
0.000 0.565 0.435
E44.0 Moderate protein-energy malnutrition
0.000 0.565 0.435
E83.3 Disorders of phosphorus metabolism
0.387 0.572 0.041
E06.5 Other chronic thyroiditis
0.000 0.574 0.426
E06.4 Drug-induced thyroiditis
0.000 0.574 0.426
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.574 0.426
E06.1 Subacute thyroiditis
0.000 0.574 0.426
E06.0 Acute thyroiditis
0.000 0.574 0.426
E85.8 Other amyloidosis
0.000 0.576 0.423
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.576 0.423
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.576 0.423
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.576 0.423
G37.8 Other specified demyelinating diseases of central nervous system
0.416 0.584 0.000
E61.2 Magnesium deficiency
0.000 0.585 0.415
E83.9 Disorder of mineral metabolism, unspecified
0.324 0.586 0.090
E83.8 Other disorders of mineral metabolism
0.324 0.586 0.090
E83.2 Disorders of zinc metabolism
0.324 0.586 0.090
E83.0 Disorders of copper metabolism
0.324 0.586 0.090
E88.9 Metabolic disorder, unspecified
0.000 0.587 0.413
E88.8 Other specified metabolic disorders
0.000 0.587 0.413
E25.9 Adrenogenital disorder, unspecified
0.000 0.591 0.409
E25.8 Other adrenogenital disorders
0.000 0.591 0.409
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.591 0.409
E30.9 Disorder of puberty, unspecified
0.000 0.591 0.409
E30.8 Other disorders of puberty
0.000 0.591 0.409
E30.1 Precocious puberty
0.000 0.591 0.409
E30.0 Delayed puberty
0.000 0.591 0.409
E31.9 Polyglandular dysfunction, unspecified
0.000 0.591 0.409
E31.8 Other polyglandular dysfunction
0.000 0.591 0.409
E31.1 Polyglandular hyperfunction
0.000 0.591 0.409
E31.0 Autoimmune polyglandular failure
0.000 0.591 0.409
E32.9 Disease of thymus, unspecified
0.000 0.591 0.409
E32.8 Other diseases of thymus
0.000 0.591 0.409
E32.1 Abscess of thymus
0.000 0.591 0.409
E32.0 Persistent hyperplasia of thymus
0.000 0.591 0.409
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.591 0.409
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.591 0.409
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.591 0.409
E61.9 Deficiency of nutrient element, unspecified
0.000 0.591 0.408
E61.8 Deficiency of other specified nutrient elements
0.000 0.591 0.408
E61.7 Deficiency of multiple nutrient elements
0.000 0.591 0.408
E61.6 Vanadium deficiency
0.000 0.591 0.408
E61.5 Molybdenum deficiency
0.000 0.591 0.408
E61.4 Chromium deficiency
0.000 0.591 0.408
E61.3 Manganese deficiency
0.000 0.591 0.408
E61.0 Copper deficiency
0.000 0.591 0.408
M06.34 Rheumatoid nodule (Hand)
0.000 0.596 0.404
E23.0 Hypopituitarism
0.000 0.603 0.396
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.606 0.394
E80.4 Gilbert's syndrome
0.000 0.606 0.394
E85.4 Organ-limited amyloidosis
0.000 0.607 0.392
E27 Other disorders of adrenal gland
0.000 0.610 0.389
L43.8 Other lichen planus
0.000 0.613 0.386
L43.3 Subacute (active) lichen planus
0.000 0.618 0.382
L43.2 Lichenoid drug reaction
0.000 0.618 0.382
L43.1 Bullous lichen planus
0.000 0.618 0.382
L43.0 Hypertrophic lichen planus
0.000 0.618 0.382
G37.5 Concentric sclerosis [Balo]
0.381 0.618 0.000
G37.4 Subacute necrotising myelitis
0.381 0.618 0.000
G37.2 Central pontine myelinolysis
0.381 0.618 0.000
G37.1 Central demyelination of corpus callosum
0.381 0.618 0.000
G37.0 Diffuse sclerosis
0.381 0.618 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.619 0.380
E22.8 Other hyperfunction of pituitary gland
0.000 0.619 0.380
E55 Vitamin D deficiency
0.000 0.621 0.379
E06.9 Thyroiditis, unspecified
0.000 0.621 0.379
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.377 0.623 0.000
E22.0 Acromegaly and pituitary gigantism
0.000 0.625 0.374
E73.9 Lactose intolerance, unspecified
0.000 0.627 0.373
E88.3 Tumour lysis syndrome
0.000 0.631 0.369
E29.9 Testicular dysfunction, unspecified
0.000 0.632 0.367
E29.8 Other testicular dysfunction
0.000 0.632 0.367
E29.0 Testicular hyperfunction
0.000 0.632 0.367
E06.3 Autoimmune thyroiditis
0.000 0.633 0.367
M06.8 Other specified rheumatoid arthritis
0.001 0.633 0.366
M06.2 Rheumatoid bursitis
0.001 0.633 0.366
M06.1 Adult-onset Still's disease
0.001 0.633 0.366
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.633 0.366
M06.4 Inflammatory polyarthropathy
0.001 0.634 0.365
E26.9 Hyperaldosteronism, unspecified
0.000 0.635 0.364
E26.8 Other hyperaldosteronism
0.000 0.635 0.364
E26.1 Secondary hyperaldosteronism
0.000 0.635 0.364
E65-E68 Obesity and other hyperalimentation
0.000 0.637 0.363
E27.9 Disorder of adrenal gland, unspecified
0.000 0.650 0.350
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.657 0.343
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.661 0.338
E50.9 Vitamin A deficiency, unspecified
0.000 0.670 0.330
E50.8 Other manifestations of vitamin A deficiency
0.000 0.670 0.330
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.670 0.330
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.670 0.330
E50.5 Vitamin A deficiency with night blindness
0.000 0.670 0.330
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.670 0.330
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.670 0.330
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.670 0.330
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.670 0.330
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.670 0.330
E51.9 Thiamine deficiency, unspecified
0.000 0.670 0.330
E51.8 Other manifestations of thiamine deficiency
0.000 0.670 0.330
E51.2 Wernicke's encephalopathy
0.000 0.670 0.330
E51.1 Beriberi
0.000 0.670 0.330
E56.9 Vitamin deficiency, unspecified
0.000 0.670 0.330
E56.8 Deficiency of other vitamins
0.000 0.670 0.330
E56.1 Deficiency of vitamin K
0.000 0.670 0.330
E56.0 Deficiency of vitamin E
0.000 0.670 0.330
E63.9 Nutritional deficiency, unspecified
0.000 0.670 0.330
E63.8 Other specified nutritional deficiencies
0.000 0.670 0.330
E63.1 Imbalance of constituents of food intake
0.000 0.670 0.330
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.670 0.330
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.670 0.330
E64.8 Sequelae of other nutritional deficiencies
0.000 0.670 0.330
E64.3 Sequelae of rickets
0.000 0.670 0.330
E64.2 Sequelae of vitamin C deficiency
0.000 0.670 0.330
E64.1 Sequelae of vitamin A deficiency
0.000 0.670 0.330
E64.0 Sequelae of protein-energy malnutrition
0.000 0.670 0.330
E22.1 Hyperprolactinaemia
0.000 0.670 0.330
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.675 0.325
M06.38 Rheumatoid nodule (Other)
0.000 0.675 0.325
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.675 0.325
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.675 0.325
M06.33 Rheumatoid nodule (Forearm)
0.000 0.675 0.325
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.675 0.325
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.675 0.325
E20.8 Other hypoparathyroidism
0.000 0.678 0.322
E20.1 Pseudohypoparathyroidism
0.000 0.678 0.322
E20.0 Idiopathic hypoparathyroidism
0.000 0.678 0.322
I21 Acute myocardial infarction
0.000 0.681 0.319
G36.9 Acute disseminated demyelination, unspecified
0.319 0.681 0.000
G36.8 Other specified acute disseminated demyelination
0.319 0.681 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.319 0.681 0.000
G36.0 Neuromyelitis optica [Devic]
0.319 0.681 0.000
L41.9 Parapsoriasis, unspecified
0.000 0.683 0.316
L41.8 Other parapsoriasis
0.000 0.683 0.316
L41.5 Retiform parapsoriasis
0.000 0.683 0.316
L41.4 Large plaque parapsoriasis
0.000 0.683 0.316
L41.3 Small plaque parapsoriasis
0.000 0.683 0.316
L41.2 Lymphomatoid papulosis
0.000 0.683 0.316
L41.1 Pityriasis lichenoides chronica
0.000 0.683 0.316
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.683 0.316
L44.9 Papulosquamous disorder, unspecified
0.000 0.683 0.316
L44.8 Other specified papulosquamous disorders
0.000 0.683 0.316
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.683 0.316
L44.3 Lichen ruber moniliformis
0.000 0.683 0.316
L44.2 Lichen striatus
0.000 0.683 0.316
L44.1 Lichen nitidus
0.000 0.683 0.316
L44.0 Pityriasis rubra pilaris
0.000 0.683 0.316
E85.3 Secondary systemic amyloidosis
0.001 0.684 0.315
E34.5 Androgen resistance syndrome
0.000 0.685 0.314
E34.4 Constitutional tall stature
0.000 0.685 0.314
E34.3 Short stature, not elsewhere classified
0.000 0.685 0.314
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.685 0.314
E34.1 Other hypersecretion of intestinal hormones
0.000 0.685 0.314
E34.8 Other specified endocrine disorders
0.000 0.688 0.312
E29.1 Testicular hypofunction
0.000 0.690 0.310
E26.0 Primary hyperaldosteronism
0.000 0.697 0.302
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.703 0.296

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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