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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3095238
log Bayes Factor = 53.469
Chromosome 6   position 31,161,210  (GRCh37) Explore rs3095238 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E78.0 Pure hypercholesterolaemia
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
I25.2 Old myocardial infarction
0.000 0.001 0.999
E11 Non-insulin-dependent diabetes mellitus
0.000 0.001 0.999
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.001 0.999
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.001 0.999
E11.9 Without complications
0.000 0.001 0.999
I25.1 Atherosclerotic heart disease
0.000 0.001 0.999
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.001 0.999
I10-I15 Hypertensive diseases
0.000 0.001 0.999
I10 Essential (primary) hypertension
0.000 0.001 0.999
Chapter IX Diseases of the circulatory system
0.000 0.003 0.997
L40.5 Arthropathic psoriasis
0.000 0.003 0.997
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.005 0.995
M06 Other rheumatoid arthritis
0.000 0.005 0.995
L40-L45 Papulosquamous disorders
0.000 0.006 0.994
E70-E90 Metabolic disorders
0.000 0.006 0.994
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.010 0.990
M05-M14 Inflammatory polyarthropathies
0.000 0.011 0.989
E14 Unspecified diabetes mellitus
0.000 0.011 0.989
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.012 0.988
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.013 0.987
M45 Ankylosing spondylitis
0.000 0.013 0.987
I21 Acute myocardial infarction
0.000 0.014 0.986
M45-M49 Spondylopathies
0.000 0.015 0.985
M70-M79 Other soft tissue disorders
0.000 0.016 0.984
# Top node
0.000 0.016 0.984
E14.9 Without complications
0.000 0.019 0.981
M79 Other soft tissue disorders, not elsewhere classified
0.000 0.024 0.976
I25.5 Ischaemic cardiomyopathy
0.000 0.027 0.973
M79.6 Pain in limb
0.000 0.029 0.971
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.029 0.971
E10.3 With ophthalmic complications
0.000 0.031 0.969
K90 Intestinal malabsorption
0.000 0.031 0.969
I21.9 Acute myocardial infarction, unspecified
0.000 0.032 0.968
L43 Lichen planus
0.000 0.036 0.964
M79.65 Pain in limb (Pelvic region and thigh)
0.000 0.040 0.960
I22 Subsequent myocardial infarction
0.000 0.041 0.959
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.045 0.955
I12 Hypertensive renal disease
0.000 0.047 0.953
M75 Shoulder lesions
0.000 0.051 0.949
J45.9 Asthma, unspecified
0.000 0.055 0.945
K51.9 Ulcerative colitis, unspecified
0.943 0.057 0.000
K90-K93 Other diseases of the digestive system
0.000 0.057 0.943
K51 Ulcerative colitis
0.942 0.058 0.000
K57 Diverticular disease of intestine
0.000 0.058 0.942
Chapter XI Diseases of the digestive system
0.000 0.058 0.942
K55-K64 Other diseases of intestines
0.000 0.058 0.942
L43.9 Lichen planus, unspecified
0.000 0.060 0.940
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.060 0.940
M75.0 Adhesive capsulitis of shoulder
0.000 0.060 0.940
K58.0 Irritable bowel syndrome with diarrhoea
0.000 0.061 0.939
K58 Irritable bowel syndrome
0.000 0.063 0.937
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.064 0.936
K57.3 Diverticular disease of large intestine without perforation or abscess
0.000 0.065 0.935
I24 Other acute ischaemic heart diseases
0.000 0.067 0.933
I20 Angina pectoris
0.000 0.078 0.922
E78.2 Mixed hyperlipidaemia
0.000 0.086 0.913
M79.7 Fibromyalgia
0.000 0.087 0.913
I12.9 Hypertensive renal disease without renal failure
0.000 0.089 0.911
I21.4 Acute subendocardial myocardial infarction
0.000 0.090 0.910
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.100 0.900
G35-G37 Demyelinating diseases of the central nervous system
0.899 0.100 0.000
E78.8 Other disorders of lipoprotein metabolism
0.000 0.102 0.898
Chapter VIII Diseases of the ear and mastoid process
0.000 0.103 0.897
E11.0 With coma
0.000 0.104 0.896
I20.9 Angina pectoris, unspecified
0.000 0.111 0.889
M79.79 Fibromyalgia (Site unspecified)
0.000 0.119 0.881
M07 Psoriatic and enteropathic arthropathies
0.000 0.119 0.881
M79.1 Myalgia
0.000 0.119 0.881
K51.3 Ulcerative (chronic) rectosigmoiditis
0.879 0.121 0.000
K51.8 Other ulcerative colitis
0.878 0.122 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.122 0.878
M79.62 Pain in limb (Upper arm)
0.000 0.130 0.870
M70 Soft tissue disorders related to use, overuse and pressure
0.000 0.132 0.868
H60-H62 Diseases of external ear
0.000 0.136 0.864
K60 Fissure and fistula of anal and rectal regions
0.000 0.136 0.864
G37 Other demyelinating diseases of central nervous system
0.863 0.137 0.000
L40.0 Psoriasis vulgaris
0.000 0.138 0.862
K51.4 Pseudopolyposis of colon
0.857 0.143 0.000
K57.8 Diverticular disease of intestine, part unspecified, with perforation and abscess
0.000 0.147 0.853
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.148 0.851
K57.1 Diverticular disease of small intestine without perforation or abscess
0.000 0.149 0.851
M79.67 Pain in limb (Ankle and foot)
0.000 0.152 0.848
L40.8 Other psoriasis
0.000 0.153 0.847
E10.1 With ketoacidosis
0.000 0.154 0.846
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.155 0.845
M75.4 Impingement syndrome of shoulder
0.000 0.157 0.843
E13 Other specified diabetes mellitus
0.000 0.158 0.842
H60 Otitis externa
0.000 0.161 0.839
E74 Other disorders of carbohydrate metabolism
0.000 0.162 0.838
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.170 0.830
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.171 0.829
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.173 0.827
H65-H75 Diseases of middle ear and mastoid
0.000 0.173 0.827
M79.64 Pain in limb (Hand)
0.000 0.175 0.825
I15 Secondary hypertension
0.000 0.176 0.824
K51.5 Mucosal proctocolitis
0.822 0.178 0.000
E11.1 With ketoacidosis
0.000 0.180 0.820
K60.2 Anal fissure, unspecified
0.000 0.180 0.820
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.181 0.819
G37.9 Demyelinating disease of central nervous system, unspecified
0.818 0.182 0.000
M07.3 Other psoriatic arthropathies
0.000 0.183 0.817
K51.2 Ulcerative (chronic) proctitis
0.816 0.184 0.000
E10.4 With neurological complications
0.000 0.184 0.816
M79.18 Myalgia (Other)
0.000 0.185 0.815
K57.9 Diverticular disease of intestine, part unspecified, without perforation or abscess
0.000 0.189 0.811
E78.5 Hyperlipidaemia, unspecified
0.000 0.191 0.809
M06.4 Inflammatory polyarthropathy
0.000 0.195 0.804
K60.0 Acute anal fissure
0.000 0.200 0.800
E10.0 With coma
0.000 0.201 0.799
M79.60 Pain in limb (Multiple sites)
0.000 0.203 0.797
E10.8 With unspecified complications
0.000 0.203 0.797
M06.3 Rheumatoid nodule
0.000 0.207 0.793
H60.9 Otitis externa, unspecified
0.000 0.209 0.791
M49 Spondylopathies in diseases classified elsewhere
0.000 0.210 0.790
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.211 0.789
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.217 0.783
M70.4 Prepatellar bursitis
0.000 0.226 0.774
H71 Cholesteatoma of middle ear
0.000 0.229 0.771
M05 Seropositive rheumatoid arthritis
0.000 0.232 0.768
M75.2 Bicipital tendinitis
0.000 0.241 0.759
I25.3 Aneurysm of heart
0.000 0.243 0.757
E11.2 With renal complications
0.000 0.247 0.753
E14.3 With ophthalmic complications
0.000 0.251 0.749
H74 Other disorders of middle ear and mastoid
0.000 0.251 0.749
E10.6 With other specified complications
0.000 0.253 0.747
M46 Other inflammatory spondylopathies
0.000 0.253 0.747
E16 Other disorders of pancreatic internal secretion
0.000 0.254 0.746
I12.0 Hypertensive renal disease with renal failure
0.000 0.258 0.742
E40-E46 Malnutrition
0.000 0.260 0.740
E10.5 With peripheral circulatory complications
0.000 0.264 0.736
I24.8 Other forms of acute ischaemic heart disease
0.000 0.265 0.735
L42 Pityriasis rosea
0.000 0.269 0.731
E13.9 Without complications
0.000 0.272 0.728
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.273 0.727
E11.6 With other specified complications
0.000 0.273 0.727
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.275 0.725
K51.1 Ulcerative (chronic) ileocolitis
0.724 0.276 0.000
M79.63 Pain in limb (Forearm)
0.000 0.276 0.724
K90.8 Other intestinal malabsorption
0.000 0.278 0.722
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.000 0.278 0.722
M70.6 Trochanteric bursitis
0.000 0.278 0.722
I11 Hypertensive heart disease
0.000 0.278 0.722
K57.5 Diverticular disease of both small and large intestine without perforation or abscess
0.000 0.279 0.721
E78.1 Pure hyperglyceridaemia
0.000 0.279 0.721
L43.8 Other lichen planus
0.000 0.281 0.719
K90.9 Intestinal malabsorption, unspecified
0.000 0.282 0.718
E10.7 With multiple complications
0.000 0.283 0.717
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
I23 Certain current complications following acute myocardial infarction
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.716
E78.6 Lipoprotein deficiency
0.000 0.284 0.716
E78.3 Hyperchylomicronaemia
0.000 0.284 0.716
I13 Hypertensive heart and renal disease
0.000 0.284 0.716
H73 Other disorders of tympanic membrane
0.000 0.285 0.715
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.287 0.713
M06.8 Other specified rheumatoid arthritis
0.000 0.287 0.713
M06.2 Rheumatoid bursitis
0.000 0.287 0.713
M06.1 Adult-onset Still's disease
0.000 0.287 0.713
L44 Other papulosquamous disorders
0.000 0.287 0.713
L41 Parapsoriasis
0.000 0.287 0.713
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.287 0.713
E79 Disorders of purine and pyrimidine metabolism
0.000 0.287 0.712
E77 Disorders of glycoprotein metabolism
0.000 0.287 0.712
E76 Disorders of glycosaminoglycan metabolism
0.000 0.287 0.712
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.287 0.712
E72 Other disorders of amino-acid metabolism
0.000 0.287 0.712
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.287 0.712
E70 Disorders of aromatic amino-acid metabolism
0.000 0.287 0.712
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.287 0.712
H60.3 Other infective otitis externa
0.000 0.290 0.710
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.291 0.709
M08 Juvenile arthritis
0.000 0.291 0.709
E14.8 With unspecified complications
0.000 0.291 0.709
E14.7 With multiple complications
0.000 0.291 0.709
E14.5 With peripheral circulatory complications
0.000 0.291 0.709
E14.2 Withrenal complications
0.000 0.291 0.709
E14.1 With ketoacidosis
0.000 0.291 0.709
E14.0 With coma
0.000 0.291 0.709
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.292 0.708
G37.8 Other specified demyelinating diseases of central nervous system
0.708 0.292 0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.292 0.708
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.292 0.708
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.292 0.708
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.292 0.708
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.292 0.708
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.292 0.708
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.292 0.708
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.292 0.708
I20.0 Unstable angina
0.000 0.293 0.707
M70.46 Prepatellar bursitis-Lower Leg
0.000 0.293 0.707
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.293 0.707
M73 Soft tissue disorders in diseases classified elsewhere
0.000 0.294 0.706
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.294 0.706
M79.9 Soft tissue disorder, unspecified
0.000 0.295 0.705
E10.2 With renal complications
0.000 0.295 0.705
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.296 0.704
I22.8 Subsequent myocardial infarction of other sites
0.000 0.296 0.704
E14.6 With other specified complications
0.000 0.298 0.702
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.299 0.701
M79.3 Panniculitis, unspecified
0.000 0.300 0.700
K90.3 Pancreatic steatorrhoea
0.000 0.305 0.694
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.305 0.694
K90.1 Tropical sprue
0.000 0.305 0.694
E78.4 Other hyperlipidaemia
0.000 0.308 0.692
L43.3 Subacute (active) lichen planus
0.000 0.309 0.691
L43.2 Lichenoid drug reaction
0.000 0.309 0.691
L43.1 Bullous lichen planus
0.000 0.309 0.691
L43.0 Hypertrophic lichen planus
0.000 0.309 0.691
E84 Cystic fibrosis
0.000 0.312 0.688
K59 Other functional intestinal disorders
0.000 0.316 0.684
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.317 0.683
M77 Other enthesopathies
0.000 0.319 0.681
H61 Other disorders of external ear
0.000 0.319 0.681
M75.8 Other shoulder lesions
0.000 0.320 0.680
M79.4 Hypertrophy of (infrapatellar) fat pad
0.000 0.320 0.680
K51.0 Ulcerative (chronic) enterocolitis
0.679 0.321 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.323 0.677
K60.5 Anorectal fistula
0.000 0.323 0.677
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.324 0.676
H74.8 Other specified disorders of middle ear and mastoid
0.000 0.324 0.676
K57.4 Diverticular disease of both small and large intestine with perforation and abscess
0.000 0.325 0.675
K64 Haemorrhoids and perianal venous thrombosis
0.000 0.325 0.675
E11.4 With neurological complications
0.000 0.326 0.674
E11.5 With peripheral circulatory complications
0.000 0.327 0.673
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.328 0.672
M11 Other crystal arthropathies
0.000 0.328 0.672
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.331 0.669
E89.3 Postprocedural hypopituitarism
0.000 0.333 0.667
I15.9 Seconday hypertension, unspecified
0.000 0.339 0.661
M79.15 Myalgia (Pelvic region and thigh)
0.000 0.339 0.660
M79.61 Pain in limb (Shoulder region)
0.000 0.341 0.659
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.342 0.658
H60.8 Other otitis externa
0.000 0.344 0.656
E14.4 With neurological complications
0.000 0.346 0.654
M79.78 Fibromyalgia (Other)
0.000 0.346 0.654
M79.77 Fibromyalgia (Ankle and foot)
0.000 0.346 0.654
M79.76 Fibromyalgia (Lower leg)
0.000 0.346 0.654
M79.75 Fibromyalgia (Pelvic region and thigh)
0.000 0.346 0.654
M79.74 Fibromyalgia (Hand)
0.000 0.346 0.654
M79.73 Fibromyalgia (Forearm)
0.000 0.346 0.654
M79.72 Fibromyalgia (Upper arm)
0.000 0.346 0.654
M79.71 Fibromyalgia (Shoulder region)
0.000 0.346 0.654
E16.2 Hypoglycaemia, unspecified
0.000 0.346 0.654
I00-I02 Acute rheumatic fever
0.000 0.347 0.652
M06.34 Rheumatoid nodule (Hand)
0.000 0.348 0.652
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.348 0.652
E85 Amyloidosis
0.000 0.348 0.651
M91-M94 Chondropathies
0.000 0.349 0.651
M49.5 Collapsed vertebra in diseases classified elsewhere
0.000 0.349 0.651
M79.68 Pain in limb (Other)
0.000 0.351 0.649
M79.16 Myalgia (Lower leg)
0.000 0.354 0.646
M46.4 Discitis, unspecified
0.000 0.354 0.646
G36 Other acute disseminated demyelination
0.645 0.355 0.000
I15.1 Hypertension secondary to other renal disorders
0.000 0.357 0.643
H60.1 Cellulitis of external ear
0.000 0.357 0.643
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.640 0.360 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.361 0.639
K57.0 Diverticular disease of small intestine with perforation and abscess
0.000 0.362 0.638
I20.1 Angina pectoris with documented spasm
0.000 0.362 0.638
M14 Arthropathies in other diseases classified elsewhere
0.000 0.365 0.635
H74.4 Polyp of middle ear
0.000 0.365 0.635
H73.8 Other specified disorders of tympanic membrane
0.000 0.366 0.634
L40.3 Pustulosis palmaris et plantaris
0.000 0.368 0.632
M07.5 Arthropathy in ulcerative colitis
0.000 0.368 0.632
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.368 0.632
M07.2 Psoriatic spondylitis
0.000 0.368 0.632
M07.1 Arthritis mutilans
0.000 0.368 0.632
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.368 0.632
M79.17 Myalgia (Ankle and foot)
0.000 0.369 0.631
M79.14 Myalgia (Hand)
0.000 0.369 0.631
M79.13 Myalgia (Forearm)
0.000 0.369 0.631
M79.12 Myalgia (Upper arm)
0.000 0.369 0.631
M79.11 Myalgia (Shoulder region)
0.000 0.369 0.631
H66 Suppurative and unspecified otitis media
0.000 0.375 0.625
E83 Disorders of mineral metabolism
0.338 0.376 0.286
I24.1 Dressler's syndrome
0.000 0.377 0.623
I30-I52 Other forms of heart disease
0.000 0.377 0.623
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.000 0.377 0.623
M70.9 Unspecified soft tissue disorder related to use, overuse and pressure
0.000 0.378 0.622
M70.8 Other soft tissue disorders related to use, overuse and pressure
0.000 0.378 0.622
M70.5 Other bursitis of knee
0.000 0.378 0.622
M70.1 Bursitis of hand
0.000 0.378 0.622
M70.0 Chronic crepitant synovitis of hand and wrist
0.000 0.378 0.622
H61.1 Non-infective disorders of pinna
0.000 0.379 0.621
H60.5 Acute otitis externa, non-infective
0.000 0.380 0.620
M12 Other specific arthropathies
0.000 0.380 0.620
G37.5 Concentric sclerosis [Balo]
0.619 0.381 0.000
G37.4 Subacute necrotising myelitis
0.619 0.381 0.000
G37.2 Central pontine myelinolysis
0.619 0.381 0.000
G37.1 Central demyelination of corpus callosum
0.619 0.381 0.000
G37.0 Diffuse sclerosis
0.619 0.381 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.382 0.618
M70.65 Trochanteric bursitis-Pelvic/Thigh
0.000 0.382 0.618
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.383 0.617
I25.4 Coronary artery aneurysm
0.000 0.389 0.611
E15 Nondiabetic hypoglycaemic coma
0.000 0.389 0.610
M79.69 Pain in limb (Site unspecified)
0.000 0.390 0.610
I51 Complications and ill-defined descriptions of heart disease
0.000 0.390 0.610
I51.8 Other ill-defined heart diseases
0.000 0.391 0.609
H60.4 Cholesteatoma of external ear
0.000 0.391 0.609
M79.19 Myalgia (Site unspecified)
0.000 0.395 0.605
E13.8 With unspecified complications
0.000 0.396 0.604
E13.7 With multiple complications
0.000 0.396 0.604
E13.6 With other specified complications
0.000 0.396 0.604
E13.5 With peripheral circulatory complications
0.000 0.396 0.604
E13.4 With neurological complications
0.000 0.396 0.604
E13.3 With ophthalmic complications
0.000 0.396 0.604
E13.2 With renal complications
0.000 0.396 0.604
E13.1 With ketoacidosis
0.000 0.396 0.604
E13.0 With coma
0.000 0.396 0.604
H60.2 Malignant otitis externa
0.000 0.398 0.602
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.399 0.601
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.399 0.601
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.399 0.601
E74.2 Disorders of galactose metabolism
0.000 0.399 0.601
E74.1 Disorders of fructose metabolism
0.000 0.399 0.601
E74.0 Glycogen storage disease
0.000 0.399 0.601
M79.10 Myalgia (Multiple sites)
0.000 0.401 0.599
E20-E35 Disorders of other endocrine glands
0.000 0.402 0.598
I46 Cardiac arrest
0.000 0.403 0.597
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.406 0.594
H74.9 Disorder of middle ear and mastoid, unspecified
0.000 0.407 0.593
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.000 0.407 0.593
H68 Eustachian salpingitis and obstruction
0.000 0.407 0.593
H67 Otitis media in diseases classified elsewhere
0.000 0.407 0.593
L10-L14 Bullous disorders
0.000 0.409 0.591
I15.8 Other secondary hypertension
0.000 0.409 0.590
I15.2 Hypertension secondary to endocrine disorders
0.000 0.409 0.590
I15.0 Renovascular hypertension
0.000 0.409 0.590
M70.7 Other bursitis of hip
0.000 0.409 0.590
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.410 0.589
M70.2 Olecranon bursitis
0.000 0.413 0.587
M07.38 Other psoriatic arthropathies (Other)
0.000 0.414 0.586
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.414 0.586
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.414 0.586
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.414 0.586
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.414 0.586
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.414 0.586
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.414 0.586
I44 Atrioventricular and left bundle-branch block
0.000 0.414 0.586
I46.9 Cardiac arrest, unspecified
0.000 0.414 0.586
K59.9 Functional intestinal disorder, unspecified
0.000 0.415 0.585
M06.0 Seronegative rheumatoid arthritis
0.000 0.416 0.584
H66.3 Other chronic suppurative otitis media
0.000 0.417 0.583
M77.1 Lateral epicondylitis
0.000 0.417 0.583
M70.3 Other bursitis of elbow
0.000 0.418 0.582
M96.0 Pseudarthrosis after fusion or arthrodesis
0.000 0.419 0.581
M07.6 Other enteropathic arthropathies
0.000 0.420 0.580
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.423 0.577
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.423 0.577
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.423 0.577
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.423 0.577
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.423 0.577
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.423 0.577
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.423 0.577
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.423 0.577
L50-L54 Urticaria and erythema
0.000 0.425 0.575
K59.8 Other specified functional intestinal disorders
0.000 0.426 0.574
M46.46 Discitis, unspecified (Lumbar region)
0.000 0.427 0.573
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.427 0.573
M79.5 Residual foreign body in soft tissue
0.000 0.430 0.570
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.431 0.568
M06.38 Rheumatoid nodule (Other)
0.000 0.431 0.568
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.431 0.568
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.431 0.568
M06.33 Rheumatoid nodule (Forearm)
0.000 0.431 0.568
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.431 0.568
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.431 0.568
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.431 0.568
H62 Disorders of external ear in diseases classified elsewhere
0.000 0.432 0.567
M49.8 Spondylopathy in other diseases classified elsewhere
0.000 0.433 0.567
M49.4 Neuropathic spondylopathy
0.000 0.433 0.567
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere
0.000 0.433 0.567
M49.2 Enterobacterial spondylitis
0.000 0.433 0.567
M49.1 Brucella spondylitis
0.000 0.433 0.567
M49.0 Tuberculosis of spine
0.000 0.433 0.567
M49.54 Collapsed vertebra in diseases classified elsewhere (Thoracic region)
0.000 0.436 0.564
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.437 0.563
E11.8 With unspecified complications
0.000 0.444 0.555
M70.49 Prepatellar bursitis-Site unspec
0.000 0.445 0.555
M70.48 Prepatellar bursitis-Other
0.000 0.445 0.555
M70.47 Prepatellar bursitis-Ankle/Foot
0.000 0.445 0.555
M70.45 Prepatellar bursitis-Pelvic/Thigh
0.000 0.445 0.555
M70.44 Prepatellar bursitis-Hand
0.000 0.445 0.555
M70.43 Prepatellar bursitis-Forearm
0.000 0.445 0.555
M70.42 Prepatellar bursitis-Upper arm
0.000 0.445 0.555
M70.41 Prepatellar bursitis-Shldr region
0.000 0.445 0.555
M70.40 Prepatellar bursitis-Mult sites
0.000 0.445 0.555
E73 Lactose intolerance
0.001 0.446 0.554
E46 Unspecified protein-energy malnutrition
0.000 0.446 0.554
I44.7 Left bundle-branch block, unspecified
0.000 0.446 0.554
H61.3 Acquired stenosis of external ear canal
0.000 0.447 0.553
M05.8 Other seropositive rheumatoid arthritis
0.000 0.449 0.551
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.449 0.551
M05.1 Rheumatoid lung disease
0.000 0.449 0.551
M05.0 Felty's syndrome
0.000 0.449 0.551
E00-E07 Disorders of thyroid gland
0.000 0.451 0.549
M72 Fibroblastic disorders
0.000 0.453 0.547
I44.0 Atrioventricular block, first degree
0.000 0.455 0.545
H60.0 Abscess of external ear
0.000 0.457 0.543
M75.3 Calcific tendinitis of shoulder
0.000 0.457 0.542
H74.3 Other acquired abnormalities of ear ossicles
0.000 0.458 0.542
M65-M68 Disorders of synovium and tendon
0.000 0.462 0.538
M00-M03 Infectious arthropathies
0.000 0.462 0.538
M79.70 Fibromyalgia (Multiple sites)
0.000 0.462 0.538
I51.0 Cardiac septal defect, acquired
0.000 0.463 0.537
K59.3 Megacolon, not elsewhere classified
0.000 0.463 0.537
H74.2 Discontinuity and dislocation of ear ossicles
0.000 0.464 0.536
M46.8 Other specified inflammatory spondylopathies
0.000 0.464 0.536
M46.5 Other infective spondylopathies
0.000 0.464 0.536
M46.2 Osteomyelitis of vertebra
0.000 0.464 0.536
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.465 0.535
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.465 0.535
E16.4 Abnormal secretion of gastrin
0.000 0.465 0.535
E16.3 Increased secretion of glucagon
0.000 0.465 0.535
E16.1 Other hypoglycaemia
0.000 0.465 0.535
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.469 0.530
E45 Retarded development following protein-energy malnutrition
0.000 0.469 0.530
E43 Unspecified severe protein-energy malnutrition
0.000 0.469 0.530
E42 Marasmic kwashiorkor
0.000 0.469 0.530
E41 Nutritional marasmus
0.000 0.469 0.530
E40 Kwashiorkor
0.000 0.469 0.530
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.470 0.530
M77.4 Metatarsalgia
0.000 0.470 0.530
M80-M85 Disorders of bone density and structure
0.000 0.470 0.530
I47 Paroxysmal tachycardia
0.000 0.474 0.526
M75.9 Shoulder lesion, unspecified
0.000 0.475 0.524
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.477 0.523
H69 Other disorders of Eustachian tube
0.000 0.477 0.523
K60.4 Rectal fistula
0.000 0.478 0.522
E28 Ovarian dysfunction
0.000 0.478 0.522
M46.9 Inflammatory spondylopathy, unspecified
0.000 0.479 0.521
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.480 0.520
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.480 0.520
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.480 0.520
E89.5 Postprocedural testicular hypofunction
0.000 0.480 0.520
E89.4 Postprocedural ovarian failure
0.000 0.480 0.520
E89.1 Postprocedural hypoinsulinaemia
0.000 0.480 0.520
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.482 0.518
M99 Biomechanical lesions, not elsewhere classified
0.000 0.482 0.518
M70.69 Trochanteric bursitis-Site unspec
0.000 0.482 0.518
M70.68 Trochanteric bursitis-Other
0.000 0.482 0.518
M70.67 Trochanteric bursitis-Ankle/Foot
0.000 0.482 0.518
M70.66 Trochanteric bursitis-Lower Leg
0.000 0.482 0.518
M70.64 Trochanteric bursitis-Hand
0.000 0.482 0.518
M70.63 Trochanteric bursitis-Forearm
0.000 0.482 0.518
M70.62 Trochanteric bursitis-Upper arm
0.000 0.482 0.518
M70.61 Trochanteric bursitis-Shldr region
0.000 0.482 0.518
M70.60 Trochanteric bursitis-Mult sites
0.000 0.482 0.518
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
I23.8 Other current complications following acute myocardial infarction
0.000 0.486 0.514
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.486 0.514
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.486 0.514
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.486 0.513
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.486 0.513
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.486 0.513
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.486 0.513
M77.12 Lateral epicondylitis (Upper arm)
0.000 0.487 0.513
H73.9 Disorder of tympanic membrane, unspecified
0.000 0.488 0.512
H73.1 Chronic myringitis
0.000 0.488 0.512
H73.0 Acute myringitis
0.000 0.488 0.512
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.489 0.511
M06.18 Adult-onset Still's disease (Other)
0.000 0.489 0.511
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.489 0.511
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.489 0.511
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.489 0.511
M06.14 Adult-onset Still's disease (Hand)
0.000 0.489 0.511
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.489 0.511
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.489 0.511
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.489 0.511

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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