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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3117182
log Bayes Factor = 136.187
Chromosome 6   position 32,066,819  (GRCh37) Explore rs3117182 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
I10 Essential (primary) hypertension
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
Chapter IX Diseases of the circulatory system
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
# Top node
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
I10-I15 Hypertensive diseases
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
G35-G37 Demyelinating diseases of the central nervous system
1.000 0.000 0.000
E78.0 Pure hypercholesterolaemia
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.001 0.999
E14.9 Without complications
0.000 0.001 0.999
H36 Retinal disorders in diseases classified elsewhere
0.000 0.001 0.999
Chapter VII Diseases of the eye and adnexa
0.000 0.001 0.999
H30-H36 Disorders of choroid and retina
0.000 0.001 0.999
L40-L45 Papulosquamous disorders
0.000 0.001 0.999
Chapter XI Diseases of the digestive system
0.000 0.001 0.999
G37 Other demyelinating diseases of central nervous system
0.999 0.001 0.000
K90 Intestinal malabsorption
0.000 0.001 0.999
L40.5 Arthropathic psoriasis
0.000 0.001 0.999
K90-K93 Other diseases of the digestive system
0.000 0.002 0.998
M05-M14 Inflammatory polyarthropathies
0.000 0.002 0.998
E10.4 With neurological complications
0.000 0.003 0.997
G37.9 Demyelinating disease of central nervous system, unspecified
0.996 0.004 0.000
I35.0 Aortic (valve) stenosis
0.000 0.004 0.996
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.004 0.996
I30-I52 Other forms of heart disease
0.000 0.004 0.996
K70-K77 Diseases of liver
0.000 0.005 0.995
I35 Nonrheumatic aortic valve disorders
0.000 0.005 0.995
L43 Lichen planus
0.000 0.006 0.994
I22 Subsequent myocardial infarction
0.000 0.007 0.993
I47 Paroxysmal tachycardia
0.000 0.007 0.993
I25 Chronic ischaemic heart disease
0.000 0.007 0.993
E14.3 With ophthalmic complications
0.000 0.011 0.989
K74 Fibrosis and cirrhosis of liver
0.000 0.011 0.989
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.011 0.989
L43.9 Lichen planus, unspecified
0.000 0.012 0.988
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.012 0.988
I20 Angina pectoris
0.000 0.013 0.987
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.014 0.986
E70-E90 Metabolic disorders
0.000 0.015 0.984
M05 Seropositive rheumatoid arthritis
0.000 0.017 0.983
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.017 0.983
H43-H45 Disorders of vitreous body and globe
0.000 0.017 0.983
I47.1 Supraventricular tachycardia
0.000 0.018 0.982
H40-H42 Glaucoma
0.000 0.019 0.981
J45.9 Asthma, unspecified
0.000 0.021 0.979
K74.3 Primary biliary cirrhosis
0.000 0.023 0.977
H43 Disorders of vitreous body
0.000 0.023 0.977
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.028 0.972
I20.0 Unstable angina
0.000 0.030 0.970
H40 Glaucoma
0.000 0.031 0.969
H40.9 Glaucoma, unspecified
0.000 0.033 0.967
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.034 0.966
E07 Other disorders of thyroid
0.000 0.034 0.966
E83 Disorders of mineral metabolism
0.958 0.035 0.007
H34 Retinal vascular occlusions
0.000 0.038 0.962
I24 Other acute ischaemic heart diseases
0.000 0.040 0.960
I25.5 Ischaemic cardiomyopathy
0.000 0.040 0.960
E10.5 With peripheral circulatory complications
0.000 0.042 0.958
K51 Ulcerative colitis
0.951 0.048 0.000
K51.9 Ulcerative colitis, unspecified
0.951 0.049 0.000
H43.3 Other vitreous opacities
0.000 0.054 0.946
E07.9 Disorder of thyroid, unspecified
0.000 0.057 0.943
K51.3 Ulcerative (chronic) rectosigmoiditis
0.940 0.060 0.000
K72 Hepatic failure, not elsewhere classified
0.000 0.062 0.938
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.062 0.938
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.069 0.931
I20.9 Angina pectoris, unspecified
0.000 0.076 0.924
H43.8 Other disorders of vitreous body
0.000 0.077 0.923
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.078 0.922
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.079 0.921
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.000 0.083 0.917
E83.3 Disorders of phosphorus metabolism
0.913 0.086 0.002
I25.1 Atherosclerotic heart disease
0.000 0.086 0.914
H34.2 Other retinal artery occlusions
0.000 0.086 0.914
Chapter VI Diseases of the nervous system
0.910 0.088 0.002
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.094 0.906
E11.3 With ophthalmic complications
0.000 0.095 0.905
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.097 0.903
E11.1 With ketoacidosis
0.000 0.099 0.901
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.104 0.896
M65-M68 Disorders of synovium and tendon
0.000 0.111 0.889
G37.8 Other specified demyelinating diseases of central nervous system
0.886 0.114 0.000
I46 Cardiac arrest
0.000 0.116 0.884
E11.2 With renal complications
0.000 0.118 0.882
E11.5 With peripheral circulatory complications
0.000 0.118 0.882
G20-G26 Extrapyramidal and movement disorders
0.876 0.123 0.000
H40.1 Primary open-angle glaucoma
0.000 0.123 0.877
K51.8 Other ulcerative colitis
0.875 0.125 0.000
K50-K52 Noninfective enteritis and colitis
0.027 0.127 0.847
E06 Thyroiditis
0.000 0.127 0.873
E83.5 Disorders of calcium metabolism
0.868 0.131 0.000
K72.9 Hepatic failure, unspecified
0.000 0.133 0.867
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.134 0.866
K74.6 Other and unspecified cirrhosis of liver
0.000 0.134 0.866
K81 Cholecystitis
0.000 0.135 0.865
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.138 0.862
K82 Other diseases of gallbladder
0.000 0.139 0.861
K75 Other inflammatory liver diseases
0.000 0.139 0.861
K73 Chronic hepatitis, not elsewhere classified
0.000 0.142 0.858
M65 Synovitis and tenosynovitis
0.000 0.142 0.858
E10.2 With renal complications
0.000 0.144 0.856
I47.2 Ventricular tachycardia
0.000 0.144 0.856
E03.8 Other specified hypothyroidism
0.000 0.148 0.852
E13 Other specified diabetes mellitus
0.000 0.151 0.849
G20 Parkinson's disease
0.845 0.155 0.000
K80 Cholelithiasis
0.000 0.156 0.844
E11.0 With coma
0.000 0.158 0.842
K80.2 Calculus of gallbladder without cholecystitis
0.000 0.158 0.842
M06.3 Rheumatoid nodule
0.000 0.165 0.835
M07 Psoriatic and enteropathic arthropathies
0.000 0.167 0.833
I46.9 Cardiac arrest, unspecified
0.000 0.171 0.829
I15 Secondary hypertension
0.000 0.173 0.827
K81.9 Cholecystitis, unspecified
0.000 0.173 0.827
M65.4 Radial styloid tenosynovitis [de Quervain]
0.000 0.173 0.827
G30-G32 Other degenerative diseases of the nervous system
0.818 0.181 0.001
I47.0 Reentry ventricular arrhythmia
0.000 0.183 0.817
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.183 0.817
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.815 0.184 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.185 0.815
K74.5 Biliary cirrhosis, unspecified
0.000 0.185 0.815
E16.1 Other hypoglycaemia
0.000 0.187 0.813
K82.8 Other specified diseases of gallbladder
0.000 0.188 0.812
K81.1 Chronic cholecystitis
0.000 0.191 0.809
K51.2 Ulcerative (chronic) proctitis
0.808 0.192 0.000
K51.5 Mucosal proctocolitis
0.804 0.196 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.196 0.804
M06.0 Seronegative rheumatoid arthritis
0.000 0.196 0.804
L43.8 Other lichen planus
0.000 0.198 0.802
M06.4 Inflammatory polyarthropathy
0.000 0.203 0.797
G80-G83 Cerebral palsy and other paralytic syndromes
0.796 0.203 0.001
K51.4 Pseudopolyposis of colon
0.796 0.204 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.207 0.793
E83.9 Disorder of mineral metabolism, unspecified
0.788 0.208 0.004
L40.8 Other psoriasis
0.000 0.209 0.791
E06.3 Autoimmune thyroiditis
0.000 0.209 0.791
H34.8 Other retinal vascular occlusions
0.000 0.211 0.789
L40.0 Psoriasis vulgaris
0.000 0.211 0.789
K90.9 Intestinal malabsorption, unspecified
0.000 0.212 0.788
K72.0 Acute and subacute hepatic failure
0.000 0.213 0.787
K82.1 Hydrops of gallbladder
0.000 0.217 0.783
M65.9 Synovitis and tenosynovitis, unspecified
0.000 0.218 0.782
E78.2 Mixed hyperlipidaemia
0.000 0.219 0.781
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.219 0.781
M45-M49 Spondylopathies
0.000 0.221 0.779
E40-E46 Malnutrition
0.000 0.227 0.773
I20.1 Angina pectoris with documented spasm
0.000 0.228 0.772
I12 Hypertensive renal disease
0.000 0.231 0.769
M45 Ankylosing spondylitis
0.000 0.231 0.769
E14.4 With neurological complications
0.000 0.233 0.767
K50 Crohn's disease [regional enteritis]
0.001 0.236 0.763
G30 Alzheimer's disease
0.760 0.240 0.000
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.000 0.240 0.760
H30 Chorioretinal inflammation
0.000 0.241 0.759
I25.2 Old myocardial infarction
0.000 0.241 0.759
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.245 0.755
K75.4 Autoimmune hepatitis
0.000 0.246 0.754
E74 Other disorders of carbohydrate metabolism
0.000 0.248 0.752
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.000 0.252 0.748
E78.1 Pure hyperglyceridaemia
0.000 0.254 0.746
H43.2 Crystalline deposits in vitreous body
0.000 0.257 0.743
E13.9 Without complications
0.000 0.259 0.741
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.259 0.741
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.000 0.263 0.736
J45 Asthma
0.000 0.264 0.736
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.268 0.731
H43.9 Disorder of vitreous body, unspecified
0.000 0.269 0.731
I23 Certain current complications following acute myocardial infarction
0.000 0.271 0.729
H34.1 Central retinal artery occlusion
0.000 0.272 0.728
M06.34 Rheumatoid nodule (Hand)
0.000 0.272 0.728
G90-G99 Other disorders of the nervous system
0.726 0.274 0.000
E11.6 With other specified complications
0.000 0.275 0.725
I35.8 Other aortic valve disorders
0.000 0.275 0.725
G30.9 Alzheimer's disease, unspecified
0.724 0.276 0.000
E78.8 Other disorders of lipoprotein metabolism
0.000 0.279 0.721
I25.3 Aneurysm of heart
0.000 0.281 0.719
E10.8 With unspecified complications
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E10.6 With other specified complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.3 Pustulosis palmaris et plantaris
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
I00-I02 Acute rheumatic fever
0.000 0.283 0.717
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
E14.8 With unspecified complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.6 With other specified complications
0.000 0.283 0.717
E14.5 With peripheral circulatory complications
0.000 0.283 0.717
E14.2 Withrenal complications
0.000 0.283 0.717
E14.1 With ketoacidosis
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
I13 Hypertensive heart and renal disease
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
G36 Other acute disseminated demyelination
0.717 0.283 0.000
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.716
M06.2 Rheumatoid bursitis
0.000 0.283 0.716
M06.1 Adult-onset Still's disease
0.000 0.283 0.716
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.283 0.716
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.284 0.716
L44 Other papulosquamous disorders
0.000 0.284 0.716
L41 Parapsoriasis
0.000 0.284 0.716
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.284 0.716
G37.5 Concentric sclerosis [Balo]
0.716 0.284 0.000
G37.4 Subacute necrotising myelitis
0.716 0.284 0.000
G37.2 Central pontine myelinolysis
0.716 0.284 0.000
G37.1 Central demyelination of corpus callosum
0.716 0.284 0.000
G37.0 Diffuse sclerosis
0.716 0.284 0.000
K90.3 Pancreatic steatorrhoea
0.000 0.284 0.716
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.284 0.716
K90.1 Tropical sprue
0.000 0.284 0.716
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.284 0.716
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.284 0.715
M08 Juvenile arthritis
0.000 0.284 0.715
H43.1 Vitreous haemorrhage
0.000 0.285 0.715
M07.3 Other psoriatic arthropathies
0.000 0.286 0.714
I52 Other heart disorders in diseases classified elsewhere
0.000 0.286 0.714
I48 Atrial fibrillation and flutter
0.000 0.286 0.714
I41 Myocarditis in diseases classified elsewhere
0.000 0.286 0.714
I40 Acute myocarditis
0.000 0.286 0.714
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.286 0.714
I32 Pericarditis in diseases classified elsewhere
0.000 0.286 0.714
K77 Liver disorders in diseases classified elsewhere
0.000 0.287 0.713
K71 Toxic liver disease
0.000 0.287 0.713
L42 Pityriasis rosea
0.000 0.287 0.713
L43.3 Subacute (active) lichen planus
0.000 0.287 0.712
L43.2 Lichenoid drug reaction
0.000 0.287 0.712
L43.1 Bullous lichen planus
0.000 0.287 0.712
L43.0 Hypertrophic lichen planus
0.000 0.287 0.712
I25.6 Silent myocardial ischaemia
0.000 0.288 0.712
G25 Other extrapyramidal and movement disorders
0.711 0.289 0.000
H40.4 Glaucoma secondary to eye inflammation
0.000 0.289 0.711
K74.4 Secondary biliary cirrhosis
0.000 0.291 0.709
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.291 0.709
K74.1 Hepatic sclerosis
0.000 0.291 0.709
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.291 0.709
E78.6 Lipoprotein deficiency
0.000 0.292 0.708
E78.3 Hyperchylomicronaemia
0.000 0.292 0.708
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.292 0.708
M14 Arthropathies in other diseases classified elsewhere
0.000 0.292 0.708
E77 Disorders of glycoprotein metabolism
0.000 0.294 0.706
E76 Disorders of glycosaminoglycan metabolism
0.000 0.294 0.706
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.294 0.706
E72 Other disorders of amino-acid metabolism
0.000 0.294 0.706
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.294 0.706
E70 Disorders of aromatic amino-acid metabolism
0.000 0.294 0.706
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.294 0.706
G83 Other paralytic syndromes
0.705 0.294 0.000
M05.8 Other seropositive rheumatoid arthritis
0.000 0.295 0.705
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.295 0.705
M05.2 Rheumatoid vasculitis
0.000 0.295 0.705
M05.1 Rheumatoid lung disease
0.000 0.295 0.705
M05.0 Felty's syndrome
0.000 0.295 0.705
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.000 0.295 0.704
E88 Other metabolic disorders
0.000 0.296 0.704
I25.4 Coronary artery aneurysm
0.000 0.296 0.704
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)
0.000 0.296 0.704
H42 Glaucoma in diseases classified elsewhere
0.000 0.296 0.704
I30 Acute pericarditis
0.000 0.296 0.703
E78.4 Other hyperlipidaemia
0.000 0.297 0.702
H43.0 Vitreous prolapse
0.000 0.300 0.700
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.000 0.300 0.700
K73.9 Chronic hepatitis, unspecified
0.000 0.300 0.700
I45 Other conduction disorders
0.000 0.302 0.698
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.303 0.697
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.303 0.697
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.303 0.697
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.303 0.697
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.303 0.697
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.303 0.697
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.303 0.697
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.303 0.697
H40.6 Glaucoma secondary to drugs
0.000 0.305 0.695
H40.3 Glaucoma secondary to eye trauma
0.000 0.305 0.695
E07.1 Dyshormogenetic goitre
0.000 0.308 0.692
E07.0 Hypersecretion of calcitonin
0.000 0.308 0.692
E83.8 Other disorders of mineral metabolism
0.687 0.308 0.005
E83.2 Disorders of zinc metabolism
0.687 0.308 0.005
E83.0 Disorders of copper metabolism
0.687 0.308 0.005
H34.9 Retinal vascular occlusion, unspecified
0.000 0.310 0.690
H34.0 Transient retinal artery occlusion
0.000 0.310 0.690
K75.8 Other specified inflammatory liver diseases
0.000 0.311 0.689
I11 Hypertensive heart disease
0.000 0.312 0.688
I21 Acute myocardial infarction
0.000 0.317 0.683
K51.1 Ulcerative (chronic) ileocolitis
0.682 0.318 0.000
G93 Other disorders of brain
0.682 0.318 0.000
M12 Other specific arthropathies
0.000 0.319 0.681
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.320 0.680
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.321 0.679
M86-M90 Other osteopathies
0.000 0.321 0.678
M11 Other crystal arthropathies
0.000 0.324 0.676
J40-J47 Chronic lower respiratory diseases
0.000 0.324 0.676
I15.1 Hypertension secondary to other renal disorders
0.000 0.324 0.676
K90.8 Other intestinal malabsorption
0.000 0.324 0.676
E11.8 With unspecified complications
0.000 0.325 0.675
K72.1 Chronic hepatic failure
0.000 0.327 0.673
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.669 0.330 0.001
E07.8 Other specified disorders of thyroid
0.000 0.330 0.669
Chapter X Diseases of the respiratory system
0.000 0.333 0.667
I51 Complications and ill-defined descriptions of heart disease
0.000 0.333 0.667
K50.0 Crohn's disease of small intestine
0.000 0.333 0.667
K80.8 Other cholelithiasis
0.000 0.334 0.666
I36 Nonrheumatic tricuspid valve disorders
0.000 0.338 0.661
G81 Hemiplegia
0.660 0.340 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.000 0.342 0.658
I12.9 Hypertensive renal disease without renal failure
0.000 0.344 0.656
E79 Disorders of purine and pyrimidine metabolism
0.001 0.346 0.654
I31 Other diseases of pericardium
0.000 0.347 0.653
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.348 0.652
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.349 0.651
G40-G47 Episodic and paroxysmal disorders
0.650 0.350 0.000
H40.5 Glaucoma secondary to other eye disorders
0.000 0.354 0.646
M70-M79 Other soft tissue disorders
0.000 0.357 0.643
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.359 0.641
I22.8 Subsequent myocardial infarction of other sites
0.000 0.359 0.640
E84 Cystic fibrosis
0.001 0.360 0.640
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)
0.000 0.360 0.640
G83.4 Cauda equina syndrome
0.639 0.361 0.000
K50.8 Other Crohn's disease
0.001 0.362 0.638
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.000 0.363 0.637
E11.4 With neurological complications
0.000 0.363 0.637
G93.8 Other specified disorders of brain
0.637 0.363 0.000
K82.2 Perforation of gallbladder
0.000 0.364 0.636
I51.8 Other ill-defined heart diseases
0.000 0.366 0.634
I15.9 Seconday hypertension, unspecified
0.000 0.366 0.634
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.366 0.634
I46.1 Sudden cardiac death, so described
0.000 0.366 0.633
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.000 0.367 0.633
G93.4 Encephalopathy, unspecified
0.631 0.369 0.000
I37 Pulmonary valve disorders
0.000 0.370 0.630
G23 Other degenerative diseases of basal ganglia
0.628 0.371 0.000
G21 Secondary Parkinsonism
0.628 0.371 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.628 0.371 0.000
G22 Parkinsonism in diseases classified elsewhere
0.628 0.371 0.000
K82.3 Fistula of gallbladder
0.000 0.372 0.628
E06.5 Other chronic thyroiditis
0.000 0.374 0.626
E06.4 Drug-induced thyroiditis
0.000 0.374 0.626
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.374 0.626
E06.1 Subacute thyroiditis
0.000 0.374 0.626
E06.0 Acute thyroiditis
0.000 0.374 0.626
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.375 0.625
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.375 0.625
K51.0 Ulcerative (chronic) enterocolitis
0.620 0.380 0.000
K75.0 Abscess of liver
0.000 0.380 0.620
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.381 0.619
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.383 0.617
K75.2 Nonspecific reactive hepatitis
0.000 0.383 0.617
K75.1 Phlebitis of portal vein
0.000 0.383 0.617
K52 Other non-infective gastro-enteritis and colitis
0.003 0.384 0.613
M88 Paget's disease of bone [osteitis deformans]
0.000 0.384 0.616
H31 Other disorders of choroid
0.000 0.384 0.615
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.385 0.615
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.385 0.615
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.385 0.615
M65.2 Calcific tendinitis
0.000 0.385 0.615
M65.0 Abscess of tendon sheath
0.000 0.385 0.615
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.390 0.610
E46 Unspecified protein-energy malnutrition
0.000 0.390 0.610
E13.8 With unspecified complications
0.000 0.391 0.609
E13.7 With multiple complications
0.000 0.391 0.609
E13.6 With other specified complications
0.000 0.391 0.609
E13.5 With peripheral circulatory complications
0.000 0.391 0.609
E13.4 With neurological complications
0.000 0.391 0.609
E13.3 With ophthalmic complications
0.000 0.391 0.609
E13.2 With renal complications
0.000 0.391 0.609
E13.1 With ketoacidosis
0.000 0.391 0.609
E13.0 With coma
0.000 0.391 0.609
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.391 0.609
M65.1 Other infective (teno)synovitis
0.000 0.394 0.606
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.394 0.606
I45.2 Bifascicular block
0.000 0.394 0.606
G25.8 Other specified extrapyramidal and movement disorders
0.605 0.395 0.000
K80.3 Calculus of bile duct with cholangitis
0.000 0.395 0.605
M00-M03 Infectious arthropathies
0.000 0.396 0.604
E06.9 Thyroiditis, unspecified
0.000 0.398 0.602
K80.1 Calculus of gallbladder with other cholecystitis
0.000 0.398 0.602
I24.1 Dressler's syndrome
0.000 0.399 0.601
G98 Other disorders of nervous system, not elsewhere classified
0.601 0.399 0.000
I44 Atrioventricular and left bundle-branch block
0.000 0.400 0.600
J46 Status asthmaticus
0.000 0.401 0.599
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.598 0.401 0.001
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.402 0.598
M06.38 Rheumatoid nodule (Other)
0.000 0.402 0.598
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.402 0.598
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.402 0.598
M06.33 Rheumatoid nodule (Forearm)
0.000 0.402 0.598
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.402 0.598
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.402 0.598
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.402 0.598
I35.2 Aortic (valve) stenosis with insufficiency
0.000 0.402 0.598
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.598 0.402 0.000
M07.6 Other enteropathic arthropathies
0.000 0.403 0.597
M07.5 Arthropathy in ulcerative colitis
0.000 0.403 0.597
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.403 0.597
M07.2 Psoriatic spondylitis
0.000 0.403 0.597
M07.1 Arthritis mutilans
0.000 0.403 0.597
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.403 0.597
I21.9 Acute myocardial infarction, unspecified
0.000 0.404 0.596
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)
0.000 0.404 0.596
M96.0 Pseudarthrosis after fusion or arthrodesis
0.000 0.404 0.595
G24 Dystonia
0.595 0.404 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.407 0.593
I15.8 Other secondary hypertension
0.000 0.407 0.593
I15.2 Hypertension secondary to endocrine disorders
0.000 0.407 0.593
I15.0 Renovascular hypertension
0.000 0.407 0.593
M65.49 Radial styloid tenosynovitis [de Quervain]-Site unspec
0.000 0.407 0.593
M65.48 Radial styloid tenosynovitis [de Quervain]-Other
0.000 0.407 0.593
M65.47 Radial styloid tenosynovitis [de Quervain]-Ankle/foot
0.000 0.407 0.593
M65.46 Radial styloid tenosynovitis [de Quervain]-Lower leg
0.000 0.407 0.593
M65.45 Radial styloid tenosynovitis [de Quervain]-Pelvic/thigh
0.000 0.407 0.593
M65.42 Radial styloid tenosynovitis [de Quervain]-Upper arm
0.000 0.407 0.593
M65.41 Radial styloid tenosynovitis [de Quervain]-Shldr region
0.000 0.407 0.593
M65.40 Radial styloid tenosynovitis [de Quervain] (Multiple sites)
0.000 0.407 0.593
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.408 0.592
J86 Pyothorax
0.000 0.408 0.592
K82.0 Obstruction of gallbladder
0.000 0.411 0.589
H30.9 Chorioretinal inflammation, unspecified
0.000 0.413 0.587
I45.8 Other specified conduction disorders
0.000 0.414 0.586
E73 Lactose intolerance
0.001 0.414 0.585
K74.0 Hepatic fibrosis
0.000 0.415 0.585
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.415 0.585
G83.1 Monoplegia of lower limb
0.582 0.418 0.000
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)
0.000 0.418 0.582
M10 Gout
0.000 0.419 0.581
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.000 0.421 0.579
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.423 0.576
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.423 0.576
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.423 0.576
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.423 0.576
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.423 0.576
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.423 0.576
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.423 0.576
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.426 0.573
M60-M63 Disorders of muscles
0.000 0.427 0.572
G96 Other disorders of central nervous system
0.572 0.428 0.000
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.428 0.571
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.428 0.571
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.428 0.571
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.428 0.571
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.428 0.571
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.428 0.571
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.428 0.571
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.428 0.571
I45.5 Other specified heart block
0.000 0.428 0.572
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.429 0.571
M88.9 Paget's disease of bone, unspecified
0.000 0.429 0.571
J43 Emphysema
0.000 0.429 0.571
H46-H48 Disorders of optic nerve and visual pathways
0.000 0.430 0.570
M65.8 Other synovitis and tenosynovitis
0.000 0.430 0.569
K82.9 Disease of gallbladder, unspecified
0.000 0.435 0.565
G44 Other headache syndromes
0.564 0.436 0.000
M77 Other enthesopathies
0.000 0.436 0.563
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.437 0.563
G00-G09 Inflammatory diseases of the central nervous system
0.562 0.437 0.001
G93.9 Disorder of brain, unspecified
0.561 0.439 0.000
G81.9 Hemiplegia, unspecified
0.561 0.439 0.000
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)
0.000 0.439 0.560
M65.98 Synovitis and tenosynovitis, unspecified (Other)
0.000 0.439 0.560
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)
0.000 0.439 0.560
K50.1 Crohn's disease of large intestine
0.000 0.442 0.557
M67 Other disorders of synovium and tendon
0.000 0.443 0.557
M49 Spondylopathies in diseases classified elsewhere
0.000 0.443 0.557
G83.9 Paralytic syndrome, unspecified
0.556 0.444 0.000
G41 Status epilepticus
0.556 0.444 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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