TreeWAS – Variant ID: rs3129683

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E05.9 Thyrotoxicosis, unspecified	1.000	0.000	0.000
K90.0 Coeliac disease	1.000	0.000	0.000
E05 Thyrotoxicosis [hyperthyroidism]	1.000	0.000	0.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000	0.000
L40 Psoriasis	1.000	0.000	0.000
R31 Unspecified haematuria	0.000	0.000	1.000
E10-E14 Diabetes mellitus	1.000	0.000	0.000
E00-E07 Disorders of thyroid gland	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
L40.9 Psoriasis, unspecified	1.000	0.000	0.000
Chapter II Neoplasms	1.000	0.000	0.000
Chapter VI Diseases of the nervous system	1.000	0.000	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	1.000	0.000	0.000
L40-L45 Papulosquamous disorders	1.000	0.000	0.000
E05.0 Thyrotoxicosis with diffuse goitre	1.000	0.000	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	1.000	0.000	0.000
G35-G37 Demyelinating diseases of the central nervous system	1.000	0.000	0.000
E10.9 Without complications	1.000	0.000	0.000
E16 Other disorders of pancreatic internal secretion	0.999	0.001	0.000
G35 Multiple sclerosis	0.999	0.001	0.000
E16.2 Hypoglycaemia, unspecified	0.999	0.001	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.999	0.001	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.999	0.001	0.000
L40.5 Arthropathic psoriasis	0.999	0.001	0.000
E03 Other hypothyroidism	0.998	0.002	0.000
K90 Intestinal malabsorption	0.997	0.003	0.000
C15-C26 Malignant neoplasms of digestive organs	0.997	0.003	0.000
I73.9 Peripheral vascular disease, unspecified	0.997	0.003	0.000
E03.9 Hypothyroidism, unspecified	0.997	0.003	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.997	0.003	0.000
I73 Other peripheral vascular diseases	0.996	0.004	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.996	0.004	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.994	0.006	0.000
Chapter XI Diseases of the digestive system	0.981	0.007	0.012
K90-K93 Other diseases of the digestive system	0.981	0.008	0.011
D60-D64 Aplastic and other anaemias	0.992	0.008	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.992	0.008	0.000
M05-M14 Inflammatory polyarthropathies	0.991	0.009	0.000
C18 Malignant neoplasm of colon	0.991	0.009	0.000
D64 Other anaemias	0.990	0.010	0.000
S00-S09 Injuries to the head	0.990	0.010	0.000
D64.9 Anaemia, unspecified	0.990	0.010	0.000
S40-S49 Injuries to the shoulder and upper arm	0.989	0.011	0.000
D80-D89 Certain disorders involving the immune mechanism	0.986	0.014	0.000
M07 Psoriatic and enteropathic arthropathies	0.986	0.014	0.000
Chapter IX Diseases of the circulatory system	0.986	0.014	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.984	0.016	0.000
E10.3 With ophthalmic complications	0.983	0.017	0.000
K70-K77 Diseases of liver	0.983	0.017	0.000
K75 Other inflammatory liver diseases	0.983	0.017	0.000
M07.3 Other psoriatic arthropathies	0.983	0.017	0.000
E10.2 With renal complications	0.982	0.018	0.000
K75.4 Autoimmune hepatitis	0.981	0.019	0.000
E10.1 With ketoacidosis	0.979	0.021	0.000
C19 Malignant neoplasm of rectosigmoid junction	0.978	0.022	0.000
E14 Unspecified diabetes mellitus	0.977	0.023	0.000
C18.9 Colon, unspecified	0.973	0.027	0.000
I74 Arterial embolism and thrombosis	0.971	0.029	0.000
C34 Malignant neoplasm of bronchus and lung	0.971	0.029	0.000
G30-G32 Other degenerative diseases of the nervous system	0.971	0.029	0.000
S46 Injury of muscle and tendon at shoulder and upper arm level	0.969	0.031	0.000
E83.1 Disorders of iron metabolism	0.000	0.034	0.966
C02 Malignant neoplasm of other and unspecified parts of tongue	0.963	0.037	0.000
Chapter VII Diseases of the eye and adnexa	0.961	0.039	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.957	0.043	0.000
S09 Other and unspecified injuries of head	0.956	0.044	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.954	0.046	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.954	0.046	0.000
D86 Sarcoidosis	0.951	0.049	0.000
S05 Injury of eye and orbit	0.950	0.050	0.000
E10.4 With neurological complications	0.949	0.051	0.000
L80-L99 Other disorders of the skin and subcutaneous tissue	0.946	0.054	0.000
H53-H54 Visual disturbances and blindness	0.946	0.054	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.945	0.055	0.000
L97 Ulcer of lower limb, not elsewhere classified	0.944	0.056	0.000
I77 Other disorders of arteries and arterioles	0.944	0.056	0.000
Chapter XX External causes of morbidity and mortality	0.943	0.057	0.000
M86-M90 Other osteopathies	0.942	0.058	0.000
K75.8 Other specified inflammatory liver diseases	0.939	0.061	0.000
C02.9 Tongue, unspecified	0.938	0.062	0.000
H47 Other disorders of optic [2nd] nerve and visual pathways	0.938	0.062	0.000
W20-W49 Exposure to inanimate mechanical forces	0.937	0.063	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.937	0.063	0.000
K90.9 Intestinal malabsorption, unspecified	0.934	0.066	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.931	0.069	0.000
W22 Striking against or struck by other objects	0.931	0.069	0.000
E14.3 With ophthalmic complications	0.930	0.070	0.000
H54 Blindness and low vision	0.930	0.070	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.929	0.071	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.929	0.071	0.000
M60-M63 Disorders of muscles	0.927	0.073	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.926	0.074	0.000
M86 Osteomyelitis	0.926	0.074	0.000
S49 Other and unspecified injuries of shoulder and upper arm	0.924	0.076	0.000
C34.3 Lower lobe, bronchus or lung	0.923	0.077	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.923	0.077	0.000
S46.2 Injury of muscle and tendon of other parts of biceps	0.921	0.079	0.000
M20-M25 Other joint disorders	0.921	0.079	0.000
W22.9 Unspecified place	0.919	0.081	0.000
K73 Chronic hepatitis, not elsewhere classified	0.919	0.081	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.919	0.081	0.000
S02 Fracture of skull and facial bones	0.916	0.084	0.000
Chapter V Mental and behavioural disorders	0.916	0.084	0.000
D86.9 Sarcoidosis, unspecified	0.915	0.085	0.000
I77.6 Arteritis, unspecified	0.915	0.085	0.000
K50-K52 Noninfective enteritis and colitis	0.263	0.088	0.649
G62 Other polyneuropathies	0.911	0.089	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.911	0.089	0.000
L50-L54 Urticaria and erythema	0.909	0.091	0.000
S09.9 Unspecified injury of head	0.909	0.091	0.000
E10.5 With peripheral circulatory complications	0.907	0.093	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.907	0.093	0.000
E20-E35 Disorders of other endocrine glands	0.902	0.098	0.000
M86.9 Osteomyelitis, unspecified	0.902	0.098	0.000
C25 Malignant neoplasm of pancreas	0.898	0.102	0.000
M35 Other systemic involvement of connective tissue	0.898	0.102	0.000
G62.9 Polyneuropathy, unspecified	0.896	0.104	0.000
C04 Malignant neoplasm of floor of mouth	0.895	0.105	0.000
K72 Hepatic failure, not elsewhere classified	0.891	0.109	0.000
M35.0 Sicca syndrome [Sjogren]	0.889	0.111	0.000
G70-G73 Diseases of myoneural junction and muscle	0.889	0.111	0.000
E70-E90 Metabolic disorders	0.886	0.114	0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)	0.886	0.114	0.000
C91 Lymphoid leukaemia	0.884	0.116	0.000
C34.0 Main bronchus	0.883	0.117	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.883	0.117	0.000
E50-E64 Other nutritional deficiencies	0.882	0.118	0.000
M62 Other disorders of muscle	0.882	0.118	0.000
H47.2 Optic atrophy	0.882	0.118	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	0.881	0.119	0.000
H54.0 Blindness, both eyes	0.881	0.119	0.000
M80-M85 Disorders of bone density and structure	0.879	0.121	0.000
M31 Other necrotising vasculopathies	0.878	0.122	0.000
V20-V29 Motorcycle rider injured in transport accident	0.878	0.122	0.000
S00 Superficial injury of head	0.877	0.123	0.000
S49.9 Unspecified injury of shoulder and upper arm	0.876	0.124	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.876	0.124	0.000
L94 Other localised connective tissue disorders	0.876	0.124	0.000
S20-S29 Injuries to the thorax	0.873	0.127	0.000
H46 Optic neuritis	0.872	0.128	0.000
E27 Other disorders of adrenal gland	0.871	0.129	0.000
C18.4 Transverse colon	0.870	0.130	0.000
S80-S89 Injuries to the knee and lower leg	0.868	0.132	0.000
E27.1 Primary adrenocortical insufficiency	0.865	0.135	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.863	0.137	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.863	0.137	0.000
G31.0 Circumscribed brain atrophy	0.862	0.138	0.000
L40.0 Psoriasis vulgaris	0.861	0.139	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.860	0.140	0.000
H54.7 Unspecified visual loss	0.860	0.140	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.859	0.141	0.000
C18.6 Descending colon	0.859	0.141	0.000
M80 Osteoporosis with pathological fracture	0.859	0.141	0.000
C85.1 B-cell lymphoma, unspecified	0.858	0.142	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.856	0.144	0.000
G31.8 Other specified degenerative diseases of nervous system	0.855	0.145	0.000
S02.4 Fracture of malar and maxillary bones	0.854	0.146	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.852	0.148	0.000
M10 Gout	0.851	0.149	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.849	0.151	0.000
S80 Superficial injury of lower leg	0.847	0.153	0.000
L10-L14 Bullous disorders	0.846	0.154	0.000
M31.6 Other giant cell arteritis	0.846	0.154	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.844	0.156	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.842	0.158	0.000
C34.2 Middle lobe, bronchus or lung	0.841	0.159	0.000
C13 Malignant neoplasm of hypopharynx	0.838	0.162	0.000
H47.3 Other disorders of optic disk	0.838	0.162	0.000
S05.3 Ocular laceration without prolapse or loss of intraocular tissue	0.837	0.163	0.000
S43.0 Dislocation of shoulder joint	0.836	0.164	0.000
I60-I69 Cerebrovascular diseases	0.833	0.167	0.000
Chapter I Certain infectious and parasitic diseases	0.833	0.167	0.000
M11 Other crystal arthropathies	0.833	0.167	0.000
C84.5 Other and unspecified T-cell lymphomas	0.831	0.169	0.000
C38 Malignant neoplasm of heart, mediastinum and pleura	0.831	0.169	0.000
C81 Hodgkin's disease	0.831	0.169	0.000
B35-B49 Mycoses	0.830	0.170	0.000
C06 Malignant neoplasm of other and unspecified parts of mouth	0.828	0.172	0.000
C18.1 Appendix	0.827	0.173	0.000
B37 Candidiasis	0.825	0.175	0.000
S21 Open wound of thorax	0.825	0.175	0.000
I70 Atherosclerosis	0.824	0.176	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.822	0.178	0.000
C25.9 Pancreas, unspecified	0.822	0.178	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.821	0.179	0.000
M62.8 Other specified disorders of muscle	0.821	0.179	0.000
S46.8 Injury of other muscles and tendons at shoulder and upper arm level	0.820	0.180	0.000
E07 Other disorders of thyroid	0.820	0.180	0.000
S00.2 Other superficial injuries of eyelid and periocular area	0.819	0.181	0.000
S46.3 Injury of muscle and tendon of triceps	0.819	0.181	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.818	0.182	0.000
D83 Common variable immunodeficiency	0.818	0.182	0.000
E13 Other specified diabetes mellitus	0.817	0.183	0.000
E10.7 With multiple complications	0.814	0.186	0.000
Q00-Q07 Congenital malformations of the nervous system	0.814	0.186	0.000
C43 Malignant melanoma of skin	0.814	0.186	0.000
G70 Myasthenia gravis and other myoneural disorders	0.813	0.187	0.000
F01 Vascular dementia	0.810	0.190	0.000
S02.40 Fracture of malar and maxillary bones (closed)	0.809	0.191	0.000
E14.5 With peripheral circulatory complications	0.807	0.193	0.000
S43.1 Dislocation of acromioclavicular joint	0.807	0.193	0.000
H47.0 Disorders of optic nerve, not elsewhere classified	0.807	0.193	0.000
V23 Motorcycle rider injured in collision with car, pick-up truck or van	0.805	0.195	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.802	0.198	0.000
L92 Granulomatous disorders of skin and subcutaneous tissue	0.802	0.198	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.801	0.199	0.000
S90-S99 Injuries to the ankle and foot	0.801	0.199	0.000
E89.0 Postprocedural hypothyroidism	0.801	0.199	0.000
S05.8 Other injuries of eye and orbit	0.798	0.201	0.000
L40.1 Generalised pustular psoriasis	0.798	0.202	0.000
W45 Foreign body or object entering through skin	0.798	0.202	0.000
B37.9 Candidiasis, unspecified	0.796	0.204	0.000
D84 Other immunodeficiencies	0.795	0.205	0.000
C01 Malignant neoplasm of base of tongue	0.795	0.205	0.000
C91.1 Chronic lymphocytic leukaemia	0.795	0.205	0.000
V01-V09 Pedestrian injured in transport accident	0.795	0.205	0.000
I73.0 Raynaud's syndrome	0.795	0.205	0.000
W22.5 Trade and service area	0.795	0.205	0.000
B37.8 Candidiasis of other sites	0.795	0.205	0.000
S09.8 Other specified injuries of head	0.794	0.206	0.000
W75-W84 Other accidental threats to breathing	0.793	0.207	0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.792	0.208	0.000
H54.4 Blindness, one eye	0.790	0.210	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.790	0.210	0.000
E10.0 With coma	0.789	0.211	0.000
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body	0.789	0.211	0.000
E40-E46 Malnutrition	0.789	0.211	0.000
L40.3 Pustulosis palmaris et plantaris	0.787	0.213	0.000
C95 Leukaemia of unspecified cell type	0.787	0.213	0.000
S80.8 Other superficial injuries of lower leg	0.786	0.214	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.785	0.215	0.000
C05 Malignant neoplasm of palate	0.785	0.215	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.783	0.217	0.000
S80.0 Contusion of knee	0.783	0.217	0.000
E10.6 With other specified complications	0.781	0.219	0.000
K72.9 Hepatic failure, unspecified	0.779	0.221	0.000
W50-W64 Exposure to animate mechanical forces	0.779	0.221	0.000
H53 Visual disturbances	0.778	0.222	0.000
E14.1 With ketoacidosis	0.777	0.223	0.000
Q50-Q56 Congenital malformations of genital organs	0.777	0.223	0.000
L52 Erythema nodosum	0.776	0.224	0.000
I65.2 Occlusion and stenosis of carotid artery	0.775	0.225	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.773	0.227	0.000
S02.2 Fracture of nasal bones	0.773	0.227	0.000
K51 Ulcerative colitis	0.001	0.228	0.771
E78.5 Hyperlipidaemia, unspecified	0.771	0.229	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.770	0.230	0.000
C07 Malignant neoplasm of parotid gland	0.769	0.231	0.000
I77.8 Other specified disorders of arteries and arterioles	0.769	0.231	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.768	0.232	0.000
G50-G59 Nerve, nerve root and plexus disorders	0.768	0.232	0.000
T79-T79 Certain early complications of trauma	0.768	0.232	0.000
K75.9 Inflammatory liver disease, unspecified	0.767	0.233	0.000
G62.0 Drug-induced polyneuropathy	0.767	0.233	0.000
K51.9 Ulcerative colitis, unspecified	0.000	0.234	0.766
W00-W19 Falls	0.766	0.234	0.000
F01.9 Vascular dementia, unspecified	0.766	0.234	0.000
M35.7 Hypermobility syndrome	0.765	0.235	0.000
L50 Urticaria	0.765	0.235	0.000
E61 Deficiency of other nutrient elements	0.764	0.235	0.000
C84.0 Mycosis fungoides	0.764	0.236	0.000
G70.0 Myasthenia gravis	0.764	0.236	0.000
F30-F39 Mood [affective] disorders	0.763	0.237	0.000
D80 Immunodeficiency with predominantly antibody defects	0.763	0.237	0.000
C04.0 Anterior floor of mouth	0.762	0.238	0.000
W27 Contact with nonpowered hand tool	0.762	0.238	0.000
K90.8 Other intestinal malabsorption	0.762	0.238	0.000
C18.5 Splenic flexure	0.761	0.239	0.000
S00.0 Superficial injury of scalp	0.761	0.239	0.000
L95 Vasculitis limited to skin, not elsewhere classified	0.759	0.241	0.000
C34.8 Overlapping lesion of bronchus and lung	0.759	0.241	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.759	0.241	0.000
E78.2 Mixed hyperlipidaemia	0.759	0.241	0.000
G31.9 Degenerative disease of nervous system, unspecified	0.757	0.243	0.000
T16 Foreign body in ear	0.757	0.243	0.000
C04.9 Floor of mouth, unspecified	0.757	0.243	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.755	0.245	0.000
L89 Decubitus ulcer	0.755	0.245	0.000
D86.3 Sarcoidosis of skin	0.754	0.245	0.000
M00-M03 Infectious arthropathies	0.754	0.246	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.754	0.246	0.000
C10 Malignant neoplasm of oropharynx	0.753	0.247	0.000
W28 Contact with powered lawn mower	0.753	0.247	0.000
V23.4 Driver injured in traffic accident	0.752	0.248	0.000
M12 Other specific arthropathies	0.752	0.248	0.000
L93 Lupus erythematosus	0.752	0.248	0.000
F31 Bipolar affective disorder	0.750	0.250	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.750	0.250	0.000
L94.0 Localised scleroderma [morphea]	0.749	0.251	0.000
S05.6 Penetrating wound of eyeball without foreign body	0.749	0.251	0.000
S00.7 Multiple superficial injuries of head	0.749	0.251	0.000
H53.1 Subjective visual disturbances	0.748	0.252	0.000
B37.0 Candidal stomatitis	0.748	0.252	0.000
B44 Aspergillosis	0.747	0.253	0.000
Q76 Congenital malformations of spine and bony thorax	0.746	0.253	0.000
G62.1 Alcoholic polyneuropathy	0.746	0.254	0.000
F23 Acute and transient psychotic disorders	0.746	0.254	0.000
S21.9 Open wound of thorax, part unspecified	0.746	0.254	0.000
W21 Striking against or struck by sports equipment	0.745	0.255	0.000
E14.4 With neurological complications	0.744	0.256	0.000
K72.0 Acute and subacute hepatic failure	0.743	0.257	0.000
S46.1 Injury of muscle and tendon of long head of biceps	0.743	0.257	0.000
D55-D59 Haemolytic anaemias	0.742	0.258	0.000
T20 Burn and corrosion of head and neck	0.742	0.258	0.000
C03 Malignant neoplasm of gum	0.741	0.259	0.000
M96.8 Other postprocedural musculoskeletal disorders	0.739	0.261	0.000
C30 Malignant neoplasm of nasal cavity and middle ear	0.738	0.262	0.000
M22 Disorders of patella	0.738	0.262	0.000
I77.2 Rupture of artery	0.737	0.263	0.000
C08 Malignant neoplasm of other and unspecified major salivary glands	0.737	0.263	0.000
E20 Hypoparathyroidism	0.735	0.264	0.000
M91-M94 Chondropathies	0.735	0.265	0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.734	0.266	0.000
C88 Malignant immunoproliferative diseases	0.733	0.266	0.000
I62 Other nontraumatic intracranial haemorrhage	0.734	0.266	0.000
T15 Foreign body on external eye	0.733	0.267	0.000
C91.9 Lymphoid leukaemia, unspecified	0.733	0.267	0.000
S10-S19 Injuries to the neck	0.732	0.268	0.000
C84.8 Cutaneous T-cell lymphoma, unspecified	0.731	0.268	0.000
S09.0 Injury of blood vessels of head, not elsewhere classified	0.731	0.269	0.000
M86.1 Other acute osteomyelitis	0.731	0.269	0.000
D86.0 Sarcoidosis of lung	0.731	0.269	0.000
C25.3 Pancreatic duct	0.731	0.269	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.730	0.270	0.000
S80.1 Contusion of other and unspecified parts of lower leg	0.730	0.270	0.000
F23.9 Acute and transient psychotic disorder, unspecified	0.729	0.271	0.000
E14.6 With other specified complications	0.729	0.271	0.000
C43.4 Malignant melanoma of scalp and neck	0.729	0.271	0.000
G30 Alzheimer's disease	0.728	0.272	0.000
D73 Diseases of spleen	0.727	0.273	0.000
M86.6 Other chronic osteomyelitis	0.726	0.273	0.000
E24 Cushing's syndrome	0.726	0.274	0.000
M80.0 Postmenopausal osteoporosis with pathological fracture	0.726	0.274	0.000
C12 Malignant neoplasm of pyriform sinus	0.726	0.274	0.000
M62.82 Other specified disorders of muscle (Upper arm)	0.726	0.274	0.000
E78.6 Lipoprotein deficiency	0.726	0.274	0.000
E14.2 Withrenal complications	0.726	0.274	0.000
F80-F89 Disorders of psychological development	0.725	0.275	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.725	0.275	0.000
S02.0 Fracture of vault of skull	0.725	0.275	0.000
K51.2 Ulcerative (chronic) proctitis	0.000	0.276	0.724
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.724	0.276	0.000
L92.3 Foreign body granuloma of skin and subcutaneous tissue	0.723	0.276	0.000
I70.0 Atherosclerosis of aorta	0.723	0.277	0.000
L94.2 Calcinosis cutis	0.723	0.277	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.722	0.278	0.000
I77.1 Stricture of artery	0.722	0.278	0.000
C38.4 Pleura	0.721	0.279	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.720	0.280	0.000
C18.8 Overlapping lesion of colon	0.720	0.280	0.000
S02.8 Fractures of other skull and facial bones	0.719	0.281	0.000
M34 Systemic sclerosis	0.719	0.281	0.000
L53 Other erythematous conditions	0.719	0.281	0.000
E14.8 With unspecified complications	0.719	0.281	0.000
F02 Dementia in other diseases classified elsewhere	0.718	0.282	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.718	0.282	0.000
W44 Foreign body entering into or through eye or natural orifice	0.718	0.282	0.000
S05.1 Contusion of eyeball and orbital tissues	0.718	0.282	0.000
M62.86 Other specified disorders of muscle (Lower leg)	0.717	0.283	0.000
E05.5 Thyroid crisis or storm	0.717	0.283	0.000
E05.4 Thyrotoxicosis factitia	0.717	0.283	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.717	0.283	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.717	0.283	0.000
L40.4 Guttate psoriasis	0.717	0.283	0.000
L40.2 Acrodermatitis continua	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.717	0.283	0.000
E00 Congenital iodine-deficiency syndrome	0.717	0.283	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.717	0.283	0.000
E12 Malnutrition-related diabetes mellitus	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
G37 Other demyelinating diseases of central nervous system	0.717	0.283	0.000
E05.8 Other thyrotoxicosis	0.717	0.283	0.000
L44 Other papulosquamous disorders	0.717	0.283	0.000
L41 Parapsoriasis	0.717	0.283	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.717	0.283	0.000
E15 Nondiabetic hypoglycaemic coma	0.717	0.283	0.000
G36 Other acute disseminated demyelination	0.717	0.283	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.717	0.283	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.717	0.283	0.000
E16.4 Abnormal secretion of gastrin	0.717	0.283	0.000
E16.3 Increased secretion of glucagon	0.717	0.283	0.000
X20-X29 Contact with venomous animals and plants	0.716	0.284	0.000
M10.0 Idiopathic gout	0.716	0.284	0.000
K73.9 Chronic hepatitis, unspecified	0.716	0.284	0.000
E03.5 Myxoedema coma	0.715	0.284	0.000
E03.4 Atrophy of thyroid (acquired)	0.715	0.284	0.000
E03.3 Postinfectious hypothyroidism	0.715	0.284	0.000
E03.1 Congenital hypothyroidism without goitre	0.715	0.284	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.715	0.284	0.000
K90.3 Pancreatic steatorrhoea	0.715	0.285	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.715	0.285	0.000
K90.1 Tropical sprue	0.715	0.285	0.000
C34.1 Upper lobe, bronchus or lung	0.715	0.285	0.000
S20 Superficial injury of thorax	0.715	0.285	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.714	0.286	0.000
C02.4 Lingual tonsil	0.714	0.286	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.713	0.287	0.000
C11 Malignant neoplasm of nasopharynx	0.713	0.287	0.000
T33-T35 Frostbite	0.713	0.287	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.713	0.287	0.000
L43 Lichen planus	0.712	0.288	0.000
D62 Acute posthaemorrhagic anaemia	0.712	0.288	0.000
K93 Disorders of other digestive organs in diseases classified elsewhere	0.703	0.289	0.008
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.711	0.289	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.711	0.289	0.000
C94 Other leukaemias of specified cell type	0.711	0.289	0.000
C86 Other specified types of T/NK-cell lymphoma	0.711	0.289	0.000
T19 Foreign body in genito-urinary tract	0.711	0.289	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.711	0.289	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.711	0.289	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.711	0.289	0.000
M08 Juvenile arthritis	0.711	0.289	0.000
D64.4 Congenital dyserythropoietic anaemia	0.710	0.290	0.000
D64.3 Other sideroblastic anaemias	0.710	0.290	0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.710	0.290	0.000
D64.1 Secondary sideroblastic anaemia due to disease	0.710	0.290	0.000
D64.0 Hereditary sideroblastic anaemia	0.710	0.290	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.710	0.290	0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.710	0.290	0.000
S08 Traumatic amputation of part of head	0.710	0.290	0.000
S07 Crushing injury of head	0.710	0.290	0.000
S04 Injury of cranial nerves	0.710	0.290	0.000
S48 Traumatic amputation of shoulder and upper arm	0.709	0.291	0.000
S45 Injury of blood vessels at shoulder and upper arm level	0.709	0.291	0.000
S44 Injury of nerves at shoulder and upper arm level	0.709	0.291	0.000
S47 Crushing injury of shoulder and upper arm	0.709	0.291	0.000
C18.3 Hepatic flexure	0.708	0.291	0.000
S00.4 Superficial injury of ear	0.708	0.292	0.000
I74.8 Embolism and thrombosis of other arteries	0.708	0.292	0.000
C06.0 Cheek mucosa	0.708	0.292	0.000
W34 Discharge from other and unspecified firearms	0.708	0.292	0.000
D82 Immunodeficiency associated with other major defects	0.707	0.293	0.000
D81 Combined immunodeficiencies	0.707	0.293	0.000
M07.6 Other enteropathic arthropathies	0.707	0.293	0.000
M07.5 Arthropathy in ulcerative colitis	0.707	0.293	0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.707	0.293	0.000
M07.2 Psoriatic spondylitis	0.707	0.293	0.000
M07.1 Arthritis mutilans	0.707	0.293	0.000
M07.0 Distal interphalangeal psoriatic arthropathy	0.707	0.293	0.000
T18 Foreign body in alimentary tract	0.707	0.293	0.000
I00-I02 Acute rheumatic fever	0.707	0.293	0.000
E10.8 With unspecified complications	0.707	0.293	0.000
M15-M19 Arthrosis	0.707	0.293	0.000
F31.9 Bipolar affective disorder, unspecified	0.706	0.294	0.000
V90-V94 Water transport accidents	0.706	0.294	0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.706	0.294	0.000
C31 Malignant neoplasm of accessory sinuses	0.706	0.294	0.000
C37 Malignant neoplasm of thymus	0.706	0.294	0.000
C33 Malignant neoplasm of trachea	0.706	0.294	0.000
K77 Liver disorders in diseases classified elsewhere	0.705	0.295	0.000
K71 Toxic liver disease	0.705	0.295	0.000
W45.6 Industrial and construction area	0.705	0.295	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.705	0.295	0.000
K75.2 Nonspecific reactive hepatitis	0.705	0.295	0.000
K75.1 Phlebitis of portal vein	0.705	0.295	0.000
G40-G47 Episodic and paroxysmal disorders	0.705	0.295	0.000
M07.38 Other psoriatic arthropathies (Other)	0.705	0.295	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.705	0.295	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.705	0.295	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.705	0.295	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.705	0.295	0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.705	0.295	0.000
A15-A19 Tuberculosis	0.704	0.296	0.000
S92 Fracture of foot, except ankle	0.704	0.296	0.000
C15 Malignant neoplasm of oesophagus	0.704	0.296	0.000
V22 Motorcycle rider injured in collision with two- or three-wheeled motor vehicle	0.703	0.297	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.702	0.298	0.000
S03 Dislocation, sprain and strain of joints and ligaments of head	0.702	0.298	0.000
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue	0.702	0.298	0.000
M86.8 Other osteomyelitis	0.701	0.299	0.000
W22.3 Sports and athletics area	0.701	0.299	0.000
G09 Sequelae of inflammatory diseases of central nervous system	0.701	0.299	0.000
E14.7 With multiple complications	0.700	0.300	0.000
E14.0 With coma	0.700	0.300	0.000
H18 Other disorders of cornea	0.700	0.300	0.000
S21.1 Open wound of front wall of thorax	0.700	0.300	0.000
M11.2 Other chondrocalcinosis	0.700	0.300	0.000
C43.9 Malignant melanoma of skin, unspecified	0.700	0.300	0.000
E07.8 Other specified disorders of thyroid	0.699	0.301	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.698	0.301	0.000
H43-H45 Disorders of vitreous body and globe	0.698	0.302	0.000
C93 Monocytic leukaemia	0.698	0.302	0.000
E11 Non-insulin-dependent diabetes mellitus	0.698	0.302	0.000
C43.6 Malignant melanoma of upper limb, including shoulder	0.697	0.303	0.000
D83.9 Common variable immunodeficiency, unspecified	0.697	0.303	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.696	0.303	0.000
K51.4 Pseudopolyposis of colon	0.000	0.304	0.696
E61.1 Iron deficiency	0.696	0.304	0.000
L81 Other disorders of pigmentation	0.695	0.305	0.000
D61 Other aplastic anaemias	0.695	0.305	0.000
S46.9 Injury of unspecified muscle and tendon at shoulder and upper arm level	0.695	0.305	0.000
S46.7 Injury of multiple muscles and tendons at shoulder and upper arm level	0.695	0.305	0.000
L13 Other bullous disorders	0.695	0.305	0.000
C13.0 Postcricoid region	0.694	0.305	0.000
C00 Malignant neoplasm of lip	0.694	0.306	0.000
H54.6 Unqualified visual loss, one eye	0.694	0.306	0.000
E25 Adrenogenital disorders	0.693	0.307	0.000
L94.8 Other specified localised connective tissue disorders	0.693	0.307	0.000
M17 Gonarthrosis [arthrosis of knee]	0.691	0.309	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations