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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3130279
log Bayes Factor = 158.281
Chromosome 6   position 32,112,626  (GRCh37) Explore rs3130279 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
I10 Essential (primary) hypertension
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
Chapter IX Diseases of the circulatory system
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
# Top node
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
I10-I15 Hypertensive diseases
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
Chapter XI Diseases of the digestive system
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
E78.0 Pure hypercholesterolaemia
0.000 0.000 1.000
Chapter VII Diseases of the eye and adnexa
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
H36 Retinal disorders in diseases classified elsewhere
0.000 0.000 1.000
H30-H36 Disorders of choroid and retina
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
L40-L45 Papulosquamous disorders
0.000 0.000 1.000
G35-G37 Demyelinating diseases of the central nervous system
1.000 0.000 0.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.001 0.999
I30-I52 Other forms of heart disease
0.000 0.001 0.999
G37 Other demyelinating diseases of central nervous system
0.999 0.001 0.000
M05-M14 Inflammatory polyarthropathies
0.000 0.001 0.999
K90 Intestinal malabsorption
0.000 0.002 0.998
I20 Angina pectoris
0.000 0.002 0.998
E10.4 With neurological complications
0.000 0.002 0.998
K90-K93 Other diseases of the digestive system
0.000 0.002 0.998
I47 Paroxysmal tachycardia
0.000 0.002 0.998
E14.9 Without complications
0.000 0.003 0.997
L43 Lichen planus
0.000 0.003 0.997
G37.9 Demyelinating disease of central nervous system, unspecified
0.997 0.003 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.000 0.003 0.997
J45.9 Asthma, unspecified
0.000 0.003 0.997
L43.9 Lichen planus, unspecified
0.000 0.005 0.995
K51.9 Ulcerative colitis, unspecified
0.995 0.005 0.000
K51 Ulcerative colitis
0.995 0.005 0.000
I35 Nonrheumatic aortic valve disorders
0.000 0.005 0.995
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.006 0.994
I35.0 Aortic (valve) stenosis
0.000 0.006 0.994
K70-K77 Diseases of liver
0.000 0.006 0.994
I25.1 Atherosclerotic heart disease
0.000 0.007 0.993
E14.3 With ophthalmic complications
0.000 0.008 0.992
I22 Subsequent myocardial infarction
0.000 0.008 0.992
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.009 0.991
K82 Other diseases of gallbladder
0.000 0.009 0.991
I20.0 Unstable angina
0.000 0.009 0.991
H43-H45 Disorders of vitreous body and globe
0.000 0.010 0.990
E70-E90 Metabolic disorders
0.000 0.010 0.989
I47.1 Supraventricular tachycardia
0.000 0.011 0.989
M05 Seropositive rheumatoid arthritis
0.000 0.011 0.989
H40-H42 Glaucoma
0.000 0.011 0.989
K51.3 Ulcerative (chronic) rectosigmoiditis
0.988 0.012 0.000
H43 Disorders of vitreous body
0.000 0.013 0.987
K74 Fibrosis and cirrhosis of liver
0.000 0.017 0.983
K80 Cholelithiasis
0.000 0.017 0.983
K82.8 Other specified diseases of gallbladder
0.000 0.017 0.983
K80.2 Calculus of gallbladder without cholecystitis
0.000 0.017 0.983
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.018 0.982
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.018 0.982
H40 Glaucoma
0.000 0.019 0.981
H40.9 Glaucoma, unspecified
0.000 0.019 0.981
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.021 0.979
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.028 0.972
I20.9 Angina pectoris, unspecified
0.000 0.029 0.971
E11.3 With ophthalmic complications
0.000 0.030 0.970
K74.3 Primary biliary cirrhosis
0.000 0.030 0.970
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.032 0.968
H43.3 Other vitreous opacities
0.000 0.036 0.964
E10.5 With peripheral circulatory complications
0.000 0.037 0.963
H34 Retinal vascular occlusions
0.000 0.037 0.963
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.040 0.960
I25.2 Old myocardial infarction
0.000 0.044 0.956
J45 Asthma
0.000 0.045 0.955
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.049 0.951
I24 Other acute ischaemic heart diseases
0.000 0.051 0.949
K72 Hepatic failure, not elsewhere classified
0.000 0.055 0.945
J40-J47 Chronic lower respiratory diseases
0.000 0.055 0.945
H43.8 Other disorders of vitreous body
0.000 0.056 0.944
E07 Other disorders of thyroid
0.000 0.060 0.940
I25.5 Ischaemic cardiomyopathy
0.000 0.060 0.940
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.061 0.939
E83 Disorders of mineral metabolism
0.924 0.062 0.013
M07 Psoriatic and enteropathic arthropathies
0.000 0.063 0.937
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.063 0.937
Chapter X Diseases of the respiratory system
0.000 0.064 0.936
I47.2 Ventricular tachycardia
0.000 0.073 0.927
K51.8 Other ulcerative colitis
0.918 0.082 0.000
K82.1 Hydrops of gallbladder
0.000 0.086 0.914
I31 Other diseases of pericardium
0.000 0.089 0.911
E11.2 With renal complications
0.000 0.091 0.909
I21 Acute myocardial infarction
0.000 0.094 0.906
E10.2 With renal complications
0.000 0.097 0.903
E07.9 Disorder of thyroid, unspecified
0.000 0.098 0.902
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.102 0.898
K50-K52 Noninfective enteritis and colitis
0.026 0.103 0.871
M07.3 Other psoriatic arthropathies
0.000 0.107 0.893
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.107 0.893
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.110 0.890
K51.2 Ulcerative (chronic) proctitis
0.889 0.111 0.000
G37.8 Other specified demyelinating diseases of central nervous system
0.888 0.112 0.000
E11.1 With ketoacidosis
0.000 0.114 0.886
I46 Cardiac arrest
0.000 0.115 0.885
K72.9 Hepatic failure, unspecified
0.000 0.115 0.885
Chapter VI Diseases of the nervous system
0.881 0.117 0.002
H34.2 Other retinal artery occlusions
0.000 0.118 0.882
E83.3 Disorders of phosphorus metabolism
0.875 0.122 0.003
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.127 0.873
E13 Other specified diabetes mellitus
0.000 0.128 0.872
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.130 0.870
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.132 0.868
M06.3 Rheumatoid nodule
0.000 0.132 0.868
G80-G83 Cerebral palsy and other paralytic syndromes
0.868 0.132 0.000
E11.5 With peripheral circulatory complications
0.000 0.133 0.867
J44 Other chronic obstructive pulmonary disease
0.000 0.134 0.866
E06 Thyroiditis
0.000 0.139 0.861
J46 Status asthmaticus
0.000 0.143 0.857
H34.8 Other retinal vascular occlusions
0.000 0.143 0.857
I31.3 Pericardial effusion (noninflammatory)
0.000 0.143 0.857
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.145 0.855
E03.8 Other specified hypothyroidism
0.000 0.150 0.850
I12 Hypertensive renal disease
0.000 0.150 0.850
I20.1 Angina pectoris with documented spasm
0.000 0.151 0.849
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.153 0.847
I47.0 Reentry ventricular arrhythmia
0.000 0.154 0.846
I15 Secondary hypertension
0.000 0.154 0.846
K80.1 Calculus of gallbladder with other cholecystitis
0.000 0.158 0.842
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.159 0.841
J95-J99 Other diseases of the respiratory system
0.000 0.161 0.839
K73 Chronic hepatitis, not elsewhere classified
0.000 0.162 0.838
K81 Cholecystitis
0.000 0.163 0.837
I46.9 Cardiac arrest, unspecified
0.000 0.163 0.837
H40.1 Primary open-angle glaucoma
0.000 0.166 0.834
M06.4 Inflammatory polyarthropathy
0.000 0.170 0.830
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.828 0.172 0.000
G81 Hemiplegia
0.826 0.174 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.174 0.826
K51.5 Mucosal proctocolitis
0.819 0.180 0.000
E11.0 With coma
0.000 0.182 0.818
I21.9 Acute myocardial infarction, unspecified
0.000 0.182 0.818
K74.6 Other and unspecified cirrhosis of liver
0.000 0.182 0.818
I45 Other conduction disorders
0.000 0.183 0.817
K50 Crohn's disease [regional enteritis]
0.001 0.183 0.816
M65-M68 Disorders of synovium and tendon
0.000 0.184 0.816
G83 Other paralytic syndromes
0.812 0.188 0.000
E16.1 Other hypoglycaemia
0.000 0.188 0.811
K75 Other inflammatory liver diseases
0.000 0.189 0.811
J86 Pyothorax
0.000 0.189 0.811
K55-K64 Other diseases of intestines
0.000 0.189 0.811
I25.3 Aneurysm of heart
0.000 0.190 0.810
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.191 0.809
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.192 0.808
K74.5 Biliary cirrhosis, unspecified
0.000 0.192 0.808
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.194 0.806
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.196 0.804
L43.8 Other lichen planus
0.000 0.197 0.803
G81.9 Hemiplegia, unspecified
0.799 0.201 0.000
M06.0 Seronegative rheumatoid arthritis
0.000 0.203 0.797
K60 Fissure and fistula of anal and rectal regions
0.000 0.203 0.797
E40-E46 Malnutrition
0.000 0.207 0.793
K80.8 Other cholelithiasis
0.000 0.207 0.793
K51.4 Pseudopolyposis of colon
0.790 0.210 0.000
L40.8 Other psoriasis
0.000 0.211 0.789
K72.0 Acute and subacute hepatic failure
0.000 0.211 0.789
H43.1 Vitreous haemorrhage
0.000 0.213 0.787
J43 Emphysema
0.000 0.216 0.784
G30-G32 Other degenerative diseases of the nervous system
0.783 0.216 0.001
K60.2 Anal fissure, unspecified
0.000 0.216 0.784
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.219 0.781
K81.9 Cholecystitis, unspecified
0.000 0.219 0.781
E13.9 Without complications
0.000 0.220 0.780
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.223 0.777
E83.5 Disorders of calcium metabolism
0.774 0.225 0.001
I30 Acute pericarditis
0.000 0.226 0.774
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.227 0.773
E88 Other metabolic disorders
0.000 0.230 0.770
E06.3 Autoimmune thyroiditis
0.000 0.231 0.769
E83.9 Disorder of mineral metabolism, unspecified
0.761 0.232 0.008
E78.2 Mixed hyperlipidaemia
0.000 0.233 0.767
J98 Other respiratory disorders
0.000 0.233 0.767
I21.4 Acute subendocardial myocardial infarction
0.000 0.236 0.764
M65 Synovitis and tenosynovitis
0.000 0.236 0.764
I25.4 Coronary artery aneurysm
0.000 0.239 0.761
I35.8 Other aortic valve disorders
0.000 0.239 0.761
E74 Other disorders of carbohydrate metabolism
0.000 0.241 0.759
I12.9 Hypertensive renal disease without renal failure
0.000 0.241 0.759
M70-M79 Other soft tissue disorders
0.000 0.242 0.758
H30 Chorioretinal inflammation
0.000 0.242 0.758
I51 Complications and ill-defined descriptions of heart disease
0.000 0.242 0.758
E05.9 Thyrotoxicosis, unspecified
0.000 0.243 0.757
G83.4 Cauda equina syndrome
0.756 0.244 0.000
M06.34 Rheumatoid nodule (Hand)
0.000 0.252 0.748
L40.0 Psoriasis vulgaris
0.000 0.254 0.746
E78.1 Pure hyperglyceridaemia
0.000 0.255 0.745
E11.6 With other specified complications
0.000 0.256 0.744
M11 Other crystal arthropathies
0.000 0.257 0.743
I23 Certain current complications following acute myocardial infarction
0.000 0.257 0.743
K51.0 Ulcerative (chronic) enterocolitis
0.737 0.263 0.000
H43.9 Disorder of vitreous body, unspecified
0.000 0.263 0.737
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.264 0.736
K82.2 Perforation of gallbladder
0.000 0.264 0.736
H34.1 Central retinal artery occlusion
0.000 0.265 0.735
G20-G26 Extrapyramidal and movement disorders
0.733 0.266 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.271 0.729
K82.3 Fistula of gallbladder
0.000 0.271 0.729
J86.9 Pyothorax without fistula
0.000 0.272 0.728
E78.8 Other disorders of lipoprotein metabolism
0.000 0.273 0.727
H40.4 Glaucoma secondary to eye inflammation
0.000 0.273 0.727
K58 Irritable bowel syndrome
0.000 0.274 0.726
M65.4 Radial styloid tenosynovitis [de Quervain]
0.000 0.275 0.725
G30 Alzheimer's disease
0.724 0.275 0.000
K60.0 Acute anal fissure
0.000 0.277 0.723
I51.8 Other ill-defined heart diseases
0.000 0.277 0.723
J98.4 Other disorders of lung
0.000 0.279 0.721
K63 Other diseases of intestine
0.000 0.279 0.721
K81.1 Chronic cholecystitis
0.000 0.279 0.721
L42 Pityriasis rosea
0.000 0.280 0.720
K50.8 Other Crohn's disease
0.000 0.282 0.717
E10.8 With unspecified complications
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E10.6 With other specified complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.3 Pustulosis palmaris et plantaris
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
I00-I02 Acute rheumatic fever
0.000 0.283 0.717
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
I13 Hypertensive heart and renal disease
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E14.8 With unspecified complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.6 With other specified complications
0.000 0.283 0.717
E14.5 With peripheral circulatory complications
0.000 0.283 0.717
E14.4 With neurological complications
0.000 0.283 0.717
E14.2 Withrenal complications
0.000 0.283 0.717
E14.1 With ketoacidosis
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.283 0.717
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.283 0.717
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
L44 Other papulosquamous disorders
0.000 0.283 0.717
L41 Parapsoriasis
0.000 0.283 0.717
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.283 0.717
G36 Other acute disseminated demyelination
0.717 0.283 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
I52 Other heart disorders in diseases classified elsewhere
0.000 0.284 0.716
I48 Atrial fibrillation and flutter
0.000 0.284 0.716
I41 Myocarditis in diseases classified elsewhere
0.000 0.284 0.716
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.284 0.716
I32 Pericarditis in diseases classified elsewhere
0.000 0.284 0.716
G37.5 Concentric sclerosis [Balo]
0.716 0.284 0.000
G37.4 Subacute necrotising myelitis
0.716 0.284 0.000
G37.2 Central pontine myelinolysis
0.716 0.284 0.000
G37.1 Central demyelination of corpus callosum
0.716 0.284 0.000
G37.0 Diffuse sclerosis
0.716 0.284 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.284 0.716
M08 Juvenile arthritis
0.000 0.284 0.716
K90.3 Pancreatic steatorrhoea
0.000 0.284 0.716
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.284 0.716
K90.1 Tropical sprue
0.000 0.284 0.716
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.284 0.716
L43.3 Subacute (active) lichen planus
0.000 0.285 0.715
L43.2 Lichenoid drug reaction
0.000 0.285 0.715
L43.1 Bullous lichen planus
0.000 0.285 0.715
L43.0 Hypertrophic lichen planus
0.000 0.285 0.715
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.000 0.285 0.715
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.286 0.714
I15.1 Hypertension secondary to other renal disorders
0.000 0.287 0.713
K77 Liver disorders in diseases classified elsewhere
0.000 0.287 0.712
K71 Toxic liver disease
0.000 0.287 0.712
E78.6 Lipoprotein deficiency
0.000 0.289 0.711
E78.3 Hyperchylomicronaemia
0.000 0.289 0.711
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.000 0.290 0.710
E77 Disorders of glycoprotein metabolism
0.000 0.290 0.709
E76 Disorders of glycosaminoglycan metabolism
0.000 0.290 0.709
E72 Other disorders of amino-acid metabolism
0.000 0.290 0.709
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.290 0.709
E70 Disorders of aromatic amino-acid metabolism
0.000 0.290 0.709
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.290 0.709
E78.4 Other hyperlipidaemia
0.000 0.291 0.709
M05.8 Other seropositive rheumatoid arthritis
0.000 0.291 0.709
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.291 0.709
M05.2 Rheumatoid vasculitis
0.000 0.291 0.709
M05.1 Rheumatoid lung disease
0.000 0.291 0.709
M05.0 Felty's syndrome
0.000 0.291 0.709
H42 Glaucoma in diseases classified elsewhere
0.000 0.291 0.709
K90.9 Intestinal malabsorption, unspecified
0.000 0.291 0.709
H43.2 Crystalline deposits in vitreous body
0.000 0.292 0.708
H43.0 Vitreous prolapse
0.000 0.292 0.708
I45.2 Bifascicular block
0.000 0.292 0.708
K80.3 Calculus of bile duct with cholangitis
0.000 0.295 0.705
K74.4 Secondary biliary cirrhosis
0.000 0.295 0.705
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.295 0.705
K74.1 Hepatic sclerosis
0.000 0.295 0.705
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.296 0.704
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.296 0.704
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.296 0.704
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.296 0.704
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.296 0.704
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.296 0.704
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.296 0.704
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.296 0.704
H40.6 Glaucoma secondary to drugs
0.000 0.296 0.703
H40.3 Glaucoma secondary to eye trauma
0.000 0.296 0.703
M75 Shoulder lesions
0.000 0.299 0.701
K58.0 Irritable bowel syndrome with diarrhoea
0.000 0.302 0.698
E79 Disorders of purine and pyrimidine metabolism
0.000 0.304 0.695
K75.4 Autoimmune hepatitis
0.000 0.304 0.695
K51.1 Ulcerative (chronic) ileocolitis
0.695 0.305 0.000
J86.0 Pyothorax with fistula
0.000 0.305 0.695
K55 Vascular disorders of intestine
0.000 0.307 0.693
H34.9 Retinal vascular occlusion, unspecified
0.000 0.310 0.690
H34.0 Transient retinal artery occlusion
0.000 0.310 0.690
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.310 0.690
I11 Hypertensive heart disease
0.000 0.311 0.688
I45.1 Other and unspecified right bundle-branch block
0.000 0.312 0.688
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.312 0.688
M75.0 Adhesive capsulitis of shoulder
0.000 0.313 0.687
J45.8 Mixed asthma
0.000 0.315 0.685
J45.1 Nonallergic asthma
0.000 0.315 0.685
I45.8 Other specified conduction disorders
0.000 0.315 0.685
I31.9 Disease of pericardium, unspecified
0.000 0.317 0.683
M14 Arthropathies in other diseases classified elsewhere
0.000 0.317 0.683
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.318 0.682
G30.9 Alzheimer's disease, unspecified
0.682 0.318 0.000
K63.9 Disease of intestine, unspecified
0.000 0.319 0.681
E11.8 With unspecified complications
0.000 0.319 0.681
K73.9 Chronic hepatitis, unspecified
0.000 0.320 0.680
K82.9 Disease of gallbladder, unspecified
0.000 0.320 0.680
H40.5 Glaucoma secondary to other eye disorders
0.000 0.321 0.679
K50.0 Crohn's disease of small intestine
0.000 0.321 0.678
K50.9 Crohn's disease, unspecified
0.000 0.322 0.678
I40 Acute myocarditis
0.000 0.322 0.678
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.001 0.322 0.677
K72.1 Chronic hepatic failure
0.000 0.322 0.677
J41 Simple and mucopurulent chronic bronchitis
0.000 0.323 0.677
K60.5 Anorectal fistula
0.000 0.323 0.677
K82.0 Obstruction of gallbladder
0.000 0.323 0.677
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.000 0.324 0.676
J43.2 Centrilobular emphysema
0.000 0.325 0.675
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.325 0.675
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.325 0.675
E07.1 Dyshormogenetic goitre
0.000 0.326 0.674
E07.0 Hypersecretion of calcitonin
0.000 0.326 0.674
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.327 0.673
J85 Abscess of lung and mediastinum
0.000 0.327 0.673
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.327 0.673
G83.1 Monoplegia of lower limb
0.673 0.327 0.000
E83.8 Other disorders of mineral metabolism
0.663 0.328 0.010
E83.2 Disorders of zinc metabolism
0.663 0.328 0.010
E83.0 Disorders of copper metabolism
0.663 0.328 0.010
M07.6 Other enteropathic arthropathies
0.000 0.328 0.672
M07.5 Arthropathy in ulcerative colitis
0.000 0.328 0.672
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.328 0.672
M07.2 Psoriatic spondylitis
0.000 0.328 0.672
M07.1 Arthritis mutilans
0.000 0.328 0.672
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.328 0.672
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.330 0.670
G20 Parkinson's disease
0.668 0.332 0.000
I36 Nonrheumatic tricuspid valve disorders
0.000 0.334 0.666
I22.8 Subsequent myocardial infarction of other sites
0.000 0.336 0.664
E84 Cystic fibrosis
0.000 0.339 0.661
M65.9 Synovitis and tenosynovitis, unspecified
0.000 0.344 0.656
I44 Atrioventricular and left bundle-branch block
0.000 0.344 0.656
G40-G47 Episodic and paroxysmal disorders
0.654 0.346 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.347 0.653
I31.8 Other specified diseases of pericardium
0.000 0.347 0.653
I31.2 Haemopericardium, not elsewhere classified
0.000 0.347 0.653
I31.0 Chronic adhesive pericarditis
0.000 0.347 0.653
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.348 0.652
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.000 0.348 0.652
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.351 0.649
J95 Postprocedural respiratory disorders, not elsewhere classified
0.000 0.352 0.648
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.353 0.647
M12 Other specific arthropathies
0.000 0.353 0.647
I15.9 Seconday hypertension, unspecified
0.000 0.353 0.647
J98.0 Diseases of bronchus, not elsewhere classified
0.000 0.354 0.646
I45.5 Other specified heart block
0.000 0.354 0.646
M77 Other enthesopathies
0.000 0.354 0.646
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.000 0.355 0.645
E46 Unspecified protein-energy malnutrition
0.000 0.355 0.645
K90.8 Other intestinal malabsorption
0.000 0.356 0.644
M45-M49 Spondylopathies
0.000 0.356 0.644
G83.9 Paralytic syndrome, unspecified
0.643 0.357 0.000
E07.8 Other specified disorders of thyroid
0.000 0.359 0.641
M07.38 Other psoriatic arthropathies (Other)
0.000 0.360 0.640
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.360 0.640
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.360 0.640
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.360 0.640
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.360 0.640
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.360 0.640
G00-G09 Inflammatory diseases of the central nervous system
0.639 0.360 0.001
M86-M90 Other osteopathies
0.000 0.363 0.637
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.365 0.635
I46.1 Sudden cardiac death, so described
0.000 0.365 0.635
I37 Pulmonary valve disorders
0.000 0.365 0.635
M75.2 Bicipital tendinitis
0.000 0.365 0.635
Q60-Q64 Congenital malformations of the urinary system
0.000 0.366 0.634
K55.2 Angiodysplasia of colon
0.000 0.371 0.629
M45 Ankylosing spondylitis
0.000 0.372 0.628
E13.8 With unspecified complications
0.000 0.375 0.625
E13.7 With multiple complications
0.000 0.375 0.625
E13.6 With other specified complications
0.000 0.375 0.625
E13.5 With peripheral circulatory complications
0.000 0.375 0.625
E13.4 With neurological complications
0.000 0.375 0.625
E13.3 With ophthalmic complications
0.000 0.375 0.625
E13.2 With renal complications
0.000 0.375 0.625
E13.1 With ketoacidosis
0.000 0.375 0.625
E13.0 With coma
0.000 0.375 0.625
I24.1 Dressler's syndrome
0.000 0.377 0.622
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.378 0.622
M06.38 Rheumatoid nodule (Other)
0.000 0.378 0.622
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.378 0.622
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.378 0.622
M06.33 Rheumatoid nodule (Forearm)
0.000 0.378 0.622
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.378 0.622
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.378 0.622
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.378 0.622
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.619 0.380 0.001
Q61 Cystic kidney disease
0.000 0.381 0.619
G82 Paraplegia and tetraplegia
0.618 0.382 0.000
G80 Infantile cerebral palsy
0.618 0.382 0.000
E06.5 Other chronic thyroiditis
0.000 0.382 0.617
E06.4 Drug-induced thyroiditis
0.000 0.382 0.617
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.382 0.617
E06.1 Subacute thyroiditis
0.000 0.382 0.617
E06.0 Acute thyroiditis
0.000 0.382 0.617
E73 Lactose intolerance
0.000 0.383 0.617
I51.0 Cardiac septal defect, acquired
0.000 0.384 0.616
J98.6 Disorders of diaphragm
0.000 0.391 0.608
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.392 0.608
M77.1 Lateral epicondylitis
0.000 0.392 0.608
I35.2 Aortic (valve) stenosis with insufficiency
0.000 0.392 0.608
M70 Soft tissue disorders related to use, overuse and pressure
0.000 0.392 0.608
E11.4 With neurological complications
0.000 0.393 0.607
I15.8 Other secondary hypertension
0.000 0.393 0.606
I15.2 Hypertension secondary to endocrine disorders
0.000 0.393 0.606
I15.0 Renovascular hypertension
0.000 0.393 0.606
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.000 0.394 0.606
K75.0 Abscess of liver
0.000 0.394 0.605
J96 Respiratory failure, not elsewhere classified
0.000 0.398 0.602
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.399 0.601
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.399 0.601
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.399 0.601
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.401 0.599
E06.9 Thyroiditis, unspecified
0.000 0.402 0.598
M75.3 Calcific tendinitis of shoulder
0.000 0.403 0.597
E88.2 Lipomatosis, not elsewhere classified
0.000 0.403 0.597
I30.9 Acute pericarditis, unspecified
0.000 0.403 0.597
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.405 0.595
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.405 0.595
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.405 0.595
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.405 0.595
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.405 0.595
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.405 0.595
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.405 0.595
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.405 0.595
H31 Other disorders of choroid
0.000 0.405 0.595
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.406 0.594
H46-H48 Disorders of optic nerve and visual pathways
0.000 0.406 0.594
G81.0 Flaccid hemiplegia
0.592 0.407 0.000
J42 Unspecified chronic bronchitis
0.000 0.408 0.592
G44 Other headache syndromes
0.589 0.411 0.000
I35.9 Aortic valve disorder, unspecified
0.000 0.412 0.588
K55.8 Other vascular disorders of intestine
0.000 0.413 0.587
J98.5 Diseases of mediastinum, not elsewhere classified
0.000 0.413 0.587

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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