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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3130532
log Bayes Factor = 51.2685
Chromosome 6   position 31,208,453  (GRCh37) Explore rs3130532 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E78.0 Pure hypercholesterolaemia
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
E10.9 Without complications
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.001 0.999
I25.2 Old myocardial infarction
0.000 0.001 0.999
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.002 0.998
I25.1 Atherosclerotic heart disease
0.000 0.003 0.997
L40.5 Arthropathic psoriasis
0.000 0.004 0.996
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.006 0.994
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.011 0.989
E14 Unspecified diabetes mellitus
0.000 0.013 0.987
E10.3 With ophthalmic complications
0.000 0.020 0.980
E14.9 Without complications
0.000 0.022 0.978
I21 Acute myocardial infarction
0.000 0.025 0.975
J45.9 Asthma, unspecified
0.000 0.025 0.975
I25.5 Ischaemic cardiomyopathy
0.000 0.029 0.971
L40-L45 Papulosquamous disorders
0.000 0.032 0.968
I22 Subsequent myocardial infarction
0.000 0.034 0.966
I10 Essential (primary) hypertension
0.000 0.035 0.965
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.037 0.963
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.037 0.963
I10-I15 Hypertensive diseases
0.000 0.038 0.962
E70-E90 Metabolic disorders
0.000 0.041 0.959
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.055 0.945
L43 Lichen planus
0.000 0.061 0.939
I12 Hypertensive renal disease
0.000 0.064 0.936
I21.9 Acute myocardial infarction, unspecified
0.000 0.064 0.936
I24 Other acute ischaemic heart diseases
0.000 0.069 0.931
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.070 0.930
Chapter IX Diseases of the circulatory system
0.000 0.077 0.923
G35-G37 Demyelinating diseases of the central nervous system
0.916 0.084 0.000
L43.9 Lichen planus, unspecified
0.000 0.085 0.915
E78.2 Mixed hyperlipidaemia
0.000 0.085 0.915
I21.4 Acute subendocardial myocardial infarction
0.000 0.091 0.909
M06 Other rheumatoid arthritis
0.000 0.094 0.906
I12.9 Hypertensive renal disease without renal failure
0.000 0.104 0.896
E11.0 With coma
0.000 0.105 0.895
G37 Other demyelinating diseases of central nervous system
0.891 0.109 0.000
E78.8 Other disorders of lipoprotein metabolism
0.000 0.114 0.886
E13 Other specified diabetes mellitus
0.000 0.121 0.879
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.129 0.871
E10.1 With ketoacidosis
0.000 0.134 0.866
G37.9 Demyelinating disease of central nervous system, unspecified
0.859 0.141 0.000
I20 Angina pectoris
0.000 0.143 0.857
E11.1 With ketoacidosis
0.000 0.147 0.853
E10.4 With neurological complications
0.000 0.153 0.847
L40.8 Other psoriasis
0.000 0.154 0.846
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.154 0.846
K90 Intestinal malabsorption
0.000 0.158 0.842
K51.9 Ulcerative colitis, unspecified
0.835 0.165 0.000
K51 Ulcerative colitis
0.834 0.166 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.176 0.824
I20.9 Angina pectoris, unspecified
0.000 0.179 0.821
L40.0 Psoriasis vulgaris
0.000 0.183 0.817
I12.0 Hypertensive renal disease with renal failure
0.000 0.184 0.816
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.184 0.816
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.185 0.815
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.189 0.811
M05-M14 Inflammatory polyarthropathies
0.000 0.192 0.808
E74 Other disorders of carbohydrate metabolism
0.000 0.192 0.808
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.195 0.805
M45 Ankylosing spondylitis
0.000 0.199 0.801
E78.5 Hyperlipidaemia, unspecified
0.000 0.200 0.800
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.201 0.799
E10.0 With coma
0.000 0.202 0.798
E10.8 With unspecified complications
0.000 0.204 0.795
E13.9 Without complications
0.000 0.207 0.793
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.213 0.787
K51.3 Ulcerative (chronic) rectosigmoiditis
0.781 0.219 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.220 0.780
M45-M49 Spondylopathies
0.000 0.222 0.778
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.224 0.776
I15 Secondary hypertension
0.000 0.227 0.773
E10.6 With other specified complications
0.000 0.227 0.773
K51.8 Other ulcerative colitis
0.772 0.228 0.000
E11.2 With renal complications
0.000 0.228 0.772
M70-M79 Other soft tissue disorders
0.000 0.236 0.764
# Top node
0.000 0.239 0.761
E10.5 With peripheral circulatory complications
0.000 0.241 0.759
E14.3 With ophthalmic complications
0.000 0.243 0.757
I25.3 Aneurysm of heart
0.000 0.247 0.753
E11.6 With other specified complications
0.000 0.249 0.751
K51.4 Pseudopolyposis of colon
0.750 0.250 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.000 0.253 0.747
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.258 0.742
E78.1 Pure hyperglyceridaemia
0.000 0.258 0.742
E11.5 With peripheral circulatory complications
0.000 0.259 0.741
I24.8 Other forms of acute ischaemic heart disease
0.000 0.261 0.739
M79.6 Pain in limb
0.000 0.267 0.733
G37.8 Other specified demyelinating diseases of central nervous system
0.731 0.269 0.000
M06.4 Inflammatory polyarthropathy
0.000 0.269 0.731
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.269 0.731
E10.2 With renal complications
0.000 0.270 0.730
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.270 0.730
M07 Psoriatic and enteropathic arthropathies
0.000 0.279 0.721
M75 Shoulder lesions
0.000 0.279 0.721
M79.65 Pain in limb (Pelvic region and thigh)
0.000 0.279 0.721
M06.3 Rheumatoid nodule
0.000 0.280 0.720
E10.7 With multiple complications
0.000 0.283 0.717
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
I23 Certain current complications following acute myocardial infarction
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.283 0.717
M75.0 Adhesive capsulitis of shoulder
0.000 0.286 0.714
E78.4 Other hyperlipidaemia
0.000 0.286 0.714
E78.6 Lipoprotein deficiency
0.000 0.288 0.712
E78.3 Hyperchylomicronaemia
0.000 0.288 0.712
K51.2 Ulcerative (chronic) proctitis
0.712 0.288 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.288 0.712
L42 Pityriasis rosea
0.000 0.290 0.710
K51.5 Mucosal proctocolitis
0.709 0.291 0.000
E14.8 With unspecified complications
0.000 0.292 0.708
E14.7 With multiple complications
0.000 0.292 0.708
E14.6 With other specified complications
0.000 0.292 0.708
E14.5 With peripheral circulatory complications
0.000 0.292 0.708
E14.2 Withrenal complications
0.000 0.292 0.708
E14.1 With ketoacidosis
0.000 0.292 0.708
E14.0 With coma
0.000 0.292 0.708
I22.8 Subsequent myocardial infarction of other sites
0.000 0.294 0.706
M79.7 Fibromyalgia
0.000 0.297 0.703
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.301 0.699
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.301 0.699
L43.8 Other lichen planus
0.000 0.302 0.698
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.302 0.698
K58.0 Irritable bowel syndrome with diarrhoea
0.000 0.304 0.696
K90-K93 Other diseases of the digestive system
0.000 0.306 0.694
L44 Other papulosquamous disorders
0.000 0.306 0.694
L41 Parapsoriasis
0.000 0.306 0.694
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.306 0.694
I11 Hypertensive heart disease
0.000 0.310 0.690
I13 Hypertensive heart and renal disease
0.000 0.310 0.690
M79.1 Myalgia
0.000 0.311 0.689
E84 Cystic fibrosis
0.000 0.312 0.687
E79 Disorders of purine and pyrimidine metabolism
0.000 0.312 0.687
E77 Disorders of glycoprotein metabolism
0.000 0.312 0.687
E76 Disorders of glycosaminoglycan metabolism
0.000 0.312 0.687
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.312 0.687
E72 Other disorders of amino-acid metabolism
0.000 0.312 0.687
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.312 0.687
E70 Disorders of aromatic amino-acid metabolism
0.000 0.312 0.687
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.312 0.687
E11.4 With neurological complications
0.000 0.317 0.683
M79.79 Fibromyalgia (Site unspecified)
0.000 0.317 0.683
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.318 0.682
E16 Other disorders of pancreatic internal secretion
0.000 0.318 0.682
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.319 0.681
Chapter XI Diseases of the digestive system
0.000 0.319 0.681
K58 Irritable bowel syndrome
0.000 0.321 0.679
K55-K64 Other diseases of intestines
0.000 0.323 0.677
K57 Diverticular disease of intestine
0.000 0.325 0.675
L43.3 Subacute (active) lichen planus
0.000 0.327 0.673
L43.2 Lichenoid drug reaction
0.000 0.327 0.673
L43.1 Bullous lichen planus
0.000 0.327 0.673
L43.0 Hypertrophic lichen planus
0.000 0.327 0.673
M07.3 Other psoriatic arthropathies
0.000 0.331 0.669
M70 Soft tissue disorders related to use, overuse and pressure
0.000 0.337 0.663
K57.3 Diverticular disease of large intestine without perforation or abscess
0.000 0.338 0.662
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.662 0.338 0.000
G36 Other acute disseminated demyelination
0.657 0.343 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.344 0.656
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.346 0.654
E40-E46 Malnutrition
0.000 0.346 0.654
E14.4 With neurological complications
0.000 0.348 0.652
M06.8 Other specified rheumatoid arthritis
0.000 0.350 0.650
M06.2 Rheumatoid bursitis
0.000 0.350 0.650
M06.1 Adult-onset Still's disease
0.000 0.350 0.650
M05 Seropositive rheumatoid arthritis
0.000 0.352 0.647
Chapter VIII Diseases of the ear and mastoid process
0.000 0.354 0.646
K51.1 Ulcerative (chronic) ileocolitis
0.642 0.358 0.000
G37.5 Concentric sclerosis [Balo]
0.639 0.361 0.000
G37.4 Subacute necrotising myelitis
0.639 0.361 0.000
G37.2 Central pontine myelinolysis
0.639 0.361 0.000
G37.1 Central demyelination of corpus callosum
0.639 0.361 0.000
G37.0 Diffuse sclerosis
0.639 0.361 0.000
I15.1 Hypertension secondary to other renal disorders
0.000 0.362 0.638
M79.18 Myalgia (Other)
0.000 0.363 0.637
L40.3 Pustulosis palmaris et plantaris
0.000 0.368 0.631
E13.8 With unspecified complications
0.000 0.370 0.630
E13.7 With multiple complications
0.000 0.370 0.630
E13.6 With other specified complications
0.000 0.370 0.630
E13.5 With peripheral circulatory complications
0.000 0.370 0.630
E13.4 With neurological complications
0.000 0.370 0.630
E13.3 With ophthalmic complications
0.000 0.370 0.630
E13.2 With renal complications
0.000 0.370 0.630
E13.1 With ketoacidosis
0.000 0.370 0.630
E13.0 With coma
0.000 0.370 0.630
M79.62 Pain in limb (Upper arm)
0.000 0.372 0.628
K51.0 Ulcerative (chronic) enterocolitis
0.628 0.372 0.000
K90.8 Other intestinal malabsorption
0.000 0.373 0.627
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.374 0.626
E85 Amyloidosis
0.000 0.375 0.624
M49 Spondylopathies in diseases classified elsewhere
0.000 0.377 0.623
I24.1 Dressler's syndrome
0.000 0.379 0.621
K90.9 Intestinal malabsorption, unspecified
0.000 0.381 0.619
M75.4 Impingement syndrome of shoulder
0.000 0.381 0.619
H60-H62 Diseases of external ear
0.000 0.386 0.614
E83 Disorders of mineral metabolism
0.327 0.386 0.287
K57.1 Diverticular disease of small intestine without perforation or abscess
0.000 0.388 0.612
M79.60 Pain in limb (Multiple sites)
0.000 0.388 0.612
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.389 0.611
K60 Fissure and fistula of anal and rectal regions
0.000 0.390 0.610
K57.8 Diverticular disease of intestine, part unspecified, with perforation and abscess
0.000 0.390 0.610
I25.4 Coronary artery aneurysm
0.000 0.391 0.609
M79.64 Pain in limb (Hand)
0.000 0.396 0.604
I00-I02 Acute rheumatic fever
0.000 0.396 0.604
K90.3 Pancreatic steatorrhoea
0.000 0.396 0.604
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.396 0.604
K90.1 Tropical sprue
0.000 0.396 0.604
I20.0 Unstable angina
0.000 0.399 0.601
H60 Otitis externa
0.000 0.405 0.595
E89.3 Postprocedural hypopituitarism
0.000 0.408 0.592
M06.34 Rheumatoid nodule (Hand)
0.000 0.409 0.590
M70.4 Prepatellar bursitis
0.000 0.410 0.590
M46 Other inflammatory spondylopathies
0.000 0.413 0.587
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.420 0.580
M08 Juvenile arthritis
0.000 0.420 0.580
E16.2 Hypoglycaemia, unspecified
0.000 0.420 0.580
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.421 0.579
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.421 0.579
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.421 0.579
E74.2 Disorders of galactose metabolism
0.000 0.421 0.579
E74.1 Disorders of fructose metabolism
0.000 0.421 0.579
E74.0 Glycogen storage disease
0.000 0.421 0.579
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.421 0.579
K60.2 Anal fissure, unspecified
0.000 0.422 0.578
H65-H75 Diseases of middle ear and mastoid
0.000 0.422 0.578
M75.2 Bicipital tendinitis
0.000 0.422 0.578
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.425 0.574
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.425 0.574
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.425 0.574
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.425 0.574
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.425 0.574
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.425 0.574
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.425 0.574
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.425 0.574
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.426 0.574
E15 Nondiabetic hypoglycaemic coma
0.000 0.427 0.573
M79.67 Pain in limb (Ankle and foot)
0.000 0.427 0.573
K60.0 Acute anal fissure
0.000 0.436 0.564
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.437 0.563
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.437 0.563
I20.1 Angina pectoris with documented spasm
0.000 0.439 0.561
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.440 0.560
E73 Lactose intolerance
0.001 0.441 0.559
H60.9 Otitis externa, unspecified
0.000 0.441 0.559
E20-E35 Disorders of other endocrine glands
0.000 0.442 0.558
M11 Other crystal arthropathies
0.000 0.443 0.557
I15.9 Seconday hypertension, unspecified
0.000 0.445 0.555
I15.8 Other secondary hypertension
0.000 0.445 0.555
I15.2 Hypertension secondary to endocrine disorders
0.000 0.445 0.555
I15.0 Renovascular hypertension
0.000 0.445 0.555
E11.8 With unspecified complications
0.000 0.447 0.553
M06.0 Seronegative rheumatoid arthritis
0.000 0.448 0.552
M73 Soft tissue disorders in diseases classified elsewhere
0.000 0.452 0.548
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.454 0.546
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.000 0.460 0.540
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.461 0.538
M70.46 Prepatellar bursitis-Lower Leg
0.000 0.462 0.538
M70.6 Trochanteric bursitis
0.000 0.464 0.536
M79.63 Pain in limb (Forearm)
0.000 0.464 0.536
M79.3 Panniculitis, unspecified
0.000 0.465 0.535
M79.9 Soft tissue disorder, unspecified
0.000 0.466 0.534
M79.15 Myalgia (Pelvic region and thigh)
0.000 0.466 0.534
H71 Cholesteatoma of middle ear
0.000 0.471 0.529
M77 Other enthesopathies
0.000 0.472 0.528
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.476 0.524
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.476 0.524
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.476 0.524
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.476 0.524
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.476 0.524
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.476 0.524
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.476 0.524
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.476 0.524
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.478 0.522
H74 Other disorders of middle ear and mastoid
0.000 0.479 0.521
M79.4 Hypertrophy of (infrapatellar) fat pad
0.000 0.481 0.519
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.481 0.518
M14 Arthropathies in other diseases classified elsewhere
0.000 0.482 0.518
M07.5 Arthropathy in ulcerative colitis
0.000 0.483 0.517
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.483 0.517
M07.2 Psoriatic spondylitis
0.000 0.483 0.517
M07.1 Arthritis mutilans
0.000 0.483 0.517
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.483 0.517
M75.8 Other shoulder lesions
0.000 0.483 0.517
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.484 0.516
M06.38 Rheumatoid nodule (Other)
0.000 0.484 0.516
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.484 0.516
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.484 0.516
M06.33 Rheumatoid nodule (Forearm)
0.000 0.484 0.516
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.484 0.516
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.484 0.516
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.484 0.516
K57.5 Diverticular disease of both small and large intestine without perforation or abscess
0.000 0.484 0.515
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
I23.8 Other current complications following acute myocardial infarction
0.000 0.486 0.514
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.486 0.514
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.486 0.514
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.487 0.513
M79.11 Myalgia (Shoulder region)
0.000 0.488 0.512
M49.5 Collapsed vertebra in diseases classified elsewhere
0.000 0.488 0.511
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.490 0.510
M91-M94 Chondropathies
0.000 0.492 0.507
M46.4 Discitis, unspecified
0.000 0.493 0.507
M12 Other specific arthropathies
0.000 0.493 0.506
M79.78 Fibromyalgia (Other)
0.000 0.496 0.504
M79.77 Fibromyalgia (Ankle and foot)
0.000 0.496 0.504
M79.76 Fibromyalgia (Lower leg)
0.000 0.496 0.504
M79.75 Fibromyalgia (Pelvic region and thigh)
0.000 0.496 0.504
M79.74 Fibromyalgia (Hand)
0.000 0.496 0.504
M79.73 Fibromyalgia (Forearm)
0.000 0.496 0.504
M79.72 Fibromyalgia (Upper arm)
0.000 0.496 0.504
M79.71 Fibromyalgia (Shoulder region)
0.000 0.496 0.504
M79.16 Myalgia (Lower leg)
0.000 0.496 0.504
K57.9 Diverticular disease of intestine, part unspecified, without perforation or abscess
0.000 0.496 0.504
H60.3 Other infective otitis externa
0.000 0.497 0.503
E88 Other metabolic disorders
0.000 0.500 0.499
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.501 0.499
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.502 0.498
L41.9 Parapsoriasis, unspecified
0.000 0.502 0.497
L41.8 Other parapsoriasis
0.000 0.502 0.497
L41.5 Retiform parapsoriasis
0.000 0.502 0.497
L41.4 Large plaque parapsoriasis
0.000 0.502 0.497
L41.3 Small plaque parapsoriasis
0.000 0.502 0.497
L41.2 Lymphomatoid papulosis
0.000 0.502 0.497
L41.1 Pityriasis lichenoides chronica
0.000 0.502 0.497
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.502 0.497
L44.9 Papulosquamous disorder, unspecified
0.000 0.502 0.497
L44.8 Other specified papulosquamous disorders
0.000 0.502 0.497
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.502 0.497
L44.3 Lichen ruber moniliformis
0.000 0.502 0.497
L44.2 Lichen striatus
0.000 0.502 0.497
L44.1 Lichen nitidus
0.000 0.502 0.497
L44.0 Pityriasis rubra pilaris
0.000 0.502 0.497
K70-K77 Diseases of liver
0.000 0.504 0.496
M79.61 Pain in limb (Shoulder region)
0.000 0.505 0.495
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.505 0.494
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.505 0.494
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.505 0.494
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.505 0.494
M79.17 Myalgia (Ankle and foot)
0.000 0.506 0.494
M79.14 Myalgia (Hand)
0.000 0.506 0.494
M79.13 Myalgia (Forearm)
0.000 0.506 0.494
M79.12 Myalgia (Upper arm)
0.000 0.506 0.494
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.507 0.493
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.507 0.493
E70.3 Albinism
0.000 0.507 0.493
E70.2 Disorders of tyrosine metabolism
0.000 0.507 0.493
E70.1 Other hyperphenylalaninaemias
0.000 0.507 0.493
E70.0 Classical phenylketonuria
0.000 0.507 0.493
E71.3 Disorders of fatty-acid metabolism
0.000 0.507 0.493
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.507 0.493
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.507 0.493
E71.0 Maple-syrup-urine disease
0.000 0.507 0.493
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.507 0.493
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.507 0.493
E72.5 Disorders of glycine metabolism
0.000 0.507 0.493
E72.4 Disorders of ornithine metabolism
0.000 0.507 0.493
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.507 0.493
E72.2 Disorders of urea cycle metabolism
0.000 0.507 0.493
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.507 0.493
E72.0 Disorders of amino-acid transport
0.000 0.507 0.493
E75.6 Lipid storage disorder, unspecified
0.000 0.507 0.493
E75.5 Other lipid storage disorders
0.000 0.507 0.493
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.507 0.493
E75.3 Sphingolipidosis, unspecified
0.000 0.507 0.493
E75.2 Other sphingolipidosis
0.000 0.507 0.493
E75.1 Other gangliosidosis
0.000 0.507 0.493
E75.0 GM2 gangliosidosis
0.000 0.507 0.493
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.507 0.493
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.507 0.493
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.507 0.493
E76.2 Other mucopolysaccharidoses
0.000 0.507 0.493
E76.1 Mucopolysaccharidosis, type II
0.000 0.507 0.493
E76.0 Mucopolysaccharidosis, type I
0.000 0.507 0.493
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.507 0.493
E77.8 Other disorders of glycoprotein metabolism
0.000 0.507 0.493
E77.1 Defects in glycoprotein degradation
0.000 0.507 0.493
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.507 0.493
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.507 0.493
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.507 0.493
E79.1 Lesch-Nyhan syndrome
0.000 0.507 0.493
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.507 0.493
E84.9 Cystic fibrosis, unspecified
0.000 0.507 0.493
E84.8 Cystic fibrosis with other manifestations
0.000 0.507 0.493
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.507 0.493
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.507 0.493
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.509 0.491
M79.19 Myalgia (Site unspecified)
0.000 0.510 0.490
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.511 0.489
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.511 0.489
E16.4 Abnormal secretion of gastrin
0.000 0.511 0.489
E16.3 Increased secretion of glucagon
0.000 0.511 0.489
E16.1 Other hypoglycaemia
0.000 0.511 0.489
M79.69 Pain in limb (Site unspecified)
0.000 0.512 0.488
K64 Haemorrhoids and perianal venous thrombosis
0.000 0.515 0.485
E28 Ovarian dysfunction
0.000 0.515 0.485
E11.3 With ophthalmic complications
0.000 0.516 0.484
K57.4 Diverticular disease of both small and large intestine with perforation and abscess
0.000 0.516 0.484
H73 Other disorders of tympanic membrane
0.000 0.517 0.483
M07.38 Other psoriatic arthropathies (Other)
0.000 0.520 0.480
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.520 0.480
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.520 0.480
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.520 0.480
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.520 0.480
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.520 0.480
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.520 0.480
K59 Other functional intestinal disorders
0.000 0.520 0.480
H74.8 Other specified disorders of middle ear and mastoid
0.000 0.523 0.477
M70.9 Unspecified soft tissue disorder related to use, overuse and pressure
0.000 0.524 0.475
M70.8 Other soft tissue disorders related to use, overuse and pressure
0.000 0.524 0.475
M70.5 Other bursitis of knee
0.000 0.524 0.475
M70.1 Bursitis of hand
0.000 0.524 0.475
M70.0 Chronic crepitant synovitis of hand and wrist
0.000 0.524 0.475
M07.6 Other enteropathic arthropathies
0.000 0.525 0.474
L50-L54 Urticaria and erythema
0.000 0.525 0.474
E50-E64 Other nutritional deficiencies
0.000 0.526 0.474
G36.9 Acute disseminated demyelination, unspecified
0.471 0.529 0.000
G36.8 Other specified acute disseminated demyelination
0.471 0.529 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.471 0.529 0.000
G36.0 Neuromyelitis optica [Devic]
0.471 0.529 0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.531 0.469
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.531 0.469
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.531 0.469
E89.5 Postprocedural testicular hypofunction
0.000 0.531 0.469
E89.1 Postprocedural hypoinsulinaemia
0.000 0.531 0.469
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.531 0.469
E45 Retarded development following protein-energy malnutrition
0.000 0.531 0.469
E43 Unspecified severe protein-energy malnutrition
0.000 0.531 0.469
E42 Marasmic kwashiorkor
0.000 0.531 0.469
E41 Nutritional marasmus
0.000 0.531 0.469
E40 Kwashiorkor
0.000 0.531 0.469
H66 Suppurative and unspecified otitis media
0.000 0.531 0.469
M79.68 Pain in limb (Other)
0.000 0.533 0.467
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.534 0.466
M06.18 Adult-onset Still's disease (Other)
0.000 0.534 0.466
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.534 0.466
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.534 0.466
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.534 0.466
M06.14 Adult-onset Still's disease (Hand)
0.000 0.534 0.466
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.534 0.466
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.534 0.466
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.534 0.466
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.534 0.466
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.534 0.466
M06.28 Rheumatoid bursitis (Other)
0.000 0.534 0.466
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.534 0.466
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.534 0.466
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.534 0.466
M06.24 Rheumatoid bursitis (Hand)
0.000 0.534 0.466
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.534 0.466
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.534 0.466
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.534 0.466
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.534 0.466
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.534 0.466
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.534 0.466
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.534 0.466
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.534 0.466
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.534 0.466
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.534 0.466
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.534 0.466
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.534 0.466
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.534 0.466
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.534 0.466
M79.10 Myalgia (Multiple sites)
0.000 0.534 0.466
M05.8 Other seropositive rheumatoid arthritis
0.000 0.536 0.464
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.536 0.464
M05.1 Rheumatoid lung disease
0.000 0.536 0.464
M05.0 Felty's syndrome
0.000 0.536 0.464
H60.8 Other otitis externa
0.000 0.536 0.464
L10-L14 Bullous disorders
0.000 0.536 0.464
E89.2 Postprocedural hypoparathyroidism
0.000 0.544 0.456
K57.0 Diverticular disease of small intestine with perforation and abscess
0.000 0.544 0.455

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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