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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3130618
log Bayes Factor = 335.092
Chromosome 6   position 31,632,134  (GRCh37) Explore rs3130618 on Ensembl!
Variant rs3130618 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
D64.9 Anaemia, unspecified
1.000 0.000 0.000
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
E05.0 Thyrotoxicosis with diffuse goitre
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
E10.3 With ophthalmic complications
1.000 0.000 0.000
E10.1 With ketoacidosis
1.000 0.000 0.000
E16.2 Hypoglycaemia, unspecified
1.000 0.000 0.000
H36.0 Diabetic retinopathy
1.000 0.000 0.000
K90.0 Coeliac disease
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E14 Unspecified diabetes mellitus
1.000 0.000 0.000
E11 Non-insulin-dependent diabetes mellitus
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
K90 Intestinal malabsorption
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
1.000 0.000 0.000
H30-H36 Disorders of choroid and retina
1.000 0.000 0.000
N00-N08 Glomerular diseases
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
N18 Chronic renal failure
1.000 0.000 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
1.000 0.000 0.000
D50-D53 Nutritional anaemias
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
E16 Other disorders of pancreatic internal secretion
1.000 0.000 0.000
D60-D64 Aplastic and other anaemias
1.000 0.000 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
E03 Other hypothyroidism
1.000 0.000 0.000
H36 Retinal disorders in diseases classified elsewhere
1.000 0.000 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
1.000 0.000 0.000
D64 Other anaemias
1.000 0.000 0.000
K75 Other inflammatory liver diseases
1.000 0.000 0.000
K70-K77 Diseases of liver
1.000 0.000 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
E14.3 With ophthalmic complications
1.000 0.000 0.000
M35.0 Sicca syndrome [Sjogren]
1.000 0.000 0.000
N17-N19 Renal failure
1.000 0.000 0.000
M35 Other systemic involvement of connective tissue
1.000 0.000 0.000
N04 Nephrotic syndrome
1.000 0.000 0.000
K90-K93 Other diseases of the digestive system
0.999 0.001 0.000
D50 Iron deficiency anaemia
0.999 0.001 0.000
I77 Other disorders of arteries and arterioles
0.999 0.001 0.000
K75.4 Autoimmune hepatitis
0.999 0.001 0.000
K52.8 Other specified non-infective gastro-enteritis and colitis
0.999 0.001 0.000
N04.9 Unspecified
0.998 0.002 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.998 0.002 0.000
E14.9 Without complications
0.998 0.002 0.000
N18.3 Chronic kidney disease, stage 3
0.998 0.002 0.000
E10.4 With neurological complications
0.998 0.002 0.000
N05 Unspecified nephritic syndrome
0.998 0.002 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.998 0.002 0.000
K90.9 Intestinal malabsorption, unspecified
0.997 0.003 0.000
I10-I15 Hypertensive diseases
0.997 0.003 0.000
N18.9 Chronic renal failure, unspecified
0.997 0.003 0.000
E11.9 Without complications
0.997 0.003 0.000
I77.1 Stricture of artery
0.997 0.003 0.000
C83.3 Large cell (diffuse)
0.996 0.004 0.000
I12 Hypertensive renal disease
0.996 0.004 0.000
H34 Retinal vascular occlusions
0.996 0.004 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.996 0.004 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.996 0.004 0.000
I74 Arterial embolism and thrombosis
0.996 0.004 0.000
E11.3 With ophthalmic complications
0.995 0.005 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.995 0.005 0.000
Chapter II Neoplasms
0.995 0.005 0.000
G56.0 Carpal tunnel syndrome
0.995 0.005 0.000
D50.9 Iron deficiency anaemia, unspecified
0.995 0.005 0.000
D51 Vitamin B12 deficiency anaemia
0.994 0.006 0.000
I73 Other peripheral vascular diseases
0.994 0.006 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.994 0.006 0.000
I71 Aortic aneurysm and dissection
0.994 0.006 0.000
E10.2 With renal complications
0.994 0.006 0.000
D69 Purpura and other haemorrhagic conditions
0.993 0.007 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.992 0.008 0.000
G56 Mononeuropathies of upper limb
0.992 0.008 0.000
H34.8 Other retinal vascular occlusions
0.992 0.008 0.000
I12.9 Hypertensive renal disease without renal failure
0.992 0.008 0.000
M24 Other specific joint derangements
0.991 0.009 0.000
M15-M19 Arthrosis
0.990 0.010 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.989 0.011 0.000
N05.2 Diffuse membranous glomerulonephritis
0.989 0.011 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.988 0.012 0.000
C85.1 B-cell lymphoma, unspecified
0.988 0.012 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.986 0.014 0.000
K50-K52 Noninfective enteritis and colitis
0.985 0.015 0.000
K52 Other non-infective gastro-enteritis and colitis
0.985 0.015 0.000
Chapter VI Diseases of the nervous system
0.985 0.015 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.985 0.015 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.984 0.016 0.000
C34 Malignant neoplasm of bronchus and lung
0.984 0.016 0.000
I73.9 Peripheral vascular disease, unspecified
0.983 0.017 0.000
Chapter I Certain infectious and parasitic diseases
0.982 0.018 0.000
D70 Agranulocytosis
0.981 0.019 0.000
M20.1 Hallux valgus (acquired)
0.000 0.019 0.981
E27.1 Primary adrenocortical insufficiency
0.979 0.021 0.000
E20-E35 Disorders of other endocrine glands
0.979 0.021 0.000
D61 Other aplastic anaemias
0.977 0.023 0.000
E27 Other disorders of adrenal gland
0.977 0.023 0.000
B35-B49 Mycoses
0.976 0.024 0.000
K75.8 Other specified inflammatory liver diseases
0.976 0.024 0.000
E89.0 Postprocedural hypothyroidism
0.973 0.027 0.000
D50.8 Other iron deficiency anaemias
0.973 0.027 0.000
D80-D89 Certain disorders involving the immune mechanism
0.972 0.028 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.971 0.029 0.000
E70-E90 Metabolic disorders
0.969 0.030 0.001
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.969 0.030 0.000
M18 Arthrosis of first carpometacarpal joint
0.968 0.032 0.000
C81 Hodgkin's disease
0.967 0.033 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.967 0.033 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.967 0.033 0.000
L93 Lupus erythematosus
0.966 0.034 0.000
B37 Candidiasis
0.965 0.035 0.000
L20-L30 Dermatitis and eczema
0.965 0.035 0.000
E50-E64 Other nutritional deficiencies
0.965 0.035 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.965 0.035 0.000
I05-I09 Chronic rheumatic heart diseases
0.962 0.038 0.000
M70-M79 Other soft tissue disorders
0.959 0.041 0.000
R31 Unspecified haematuria
0.000 0.041 0.959
K73 Chronic hepatitis, not elsewhere classified
0.958 0.042 0.000
C34.3 Lower lobe, bronchus or lung
0.957 0.043 0.000
L28 Lichen simplex chronicus and prurigo
0.957 0.043 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.956 0.044 0.000
I12.0 Hypertensive renal disease with renal failure
0.956 0.044 0.000
L10-L14 Bullous disorders
0.955 0.045 0.000
E11.5 With peripheral circulatory complications
0.954 0.046 0.000
M24.1 Other articular cartilage disorders
0.952 0.048 0.000
D61.9 Aplastic anaemia, unspecified
0.952 0.048 0.000
E07 Other disorders of thyroid
0.951 0.049 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.951 0.049 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.948 0.052 0.000
L40-L45 Papulosquamous disorders
0.946 0.054 0.000
H06.2 Dysthyroid exophthalmos
0.945 0.055 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.944 0.056 0.000
D69.6 Thrombocytopenia, unspecified
0.944 0.056 0.000
L28.0 Lichen simplex chronicus
0.943 0.057 0.000
B37.8 Candidiasis of other sites
0.943 0.057 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.943 0.057 0.000
Chapter XX External causes of morbidity and mortality
0.940 0.060 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.938 0.062 0.000
M17 Gonarthrosis [arthrosis of knee]
0.936 0.064 0.000
E06 Thyroiditis
0.934 0.066 0.000
L43 Lichen planus
0.933 0.067 0.000
L13 Other bullous disorders
0.933 0.067 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.924 0.076 0.000
C15-C26 Malignant neoplasms of digestive organs
0.922 0.078 0.000
I77.6 Arteritis, unspecified
0.921 0.079 0.000
L93.0 Discoid lupus erythematosus
0.920 0.080 0.000
M15 Polyarthrosis
0.920 0.080 0.000
I07 Rheumatic tricuspid valve diseases
0.920 0.080 0.000
N18.4 Chronic kidney disease, stage 4
0.920 0.080 0.000
L43.9 Lichen planus, unspecified
0.919 0.081 0.000
L13.0 Dermatitis herpetiformis
0.917 0.083 0.000
N08.5 Glomerular disorders in systemic connective tissue disorders
0.915 0.085 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.911 0.089 0.000
C91 Lymphoid leukaemia
0.910 0.090 0.000
H43-H45 Disorders of vitreous body and globe
0.909 0.091 0.000
M17.1 Other primary gonarthrosis
0.908 0.092 0.000
E11.1 With ketoacidosis
0.906 0.094 0.000
E10.5 With peripheral circulatory complications
0.905 0.095 0.000
E53 Deficiency of other B group vitamins
0.903 0.097 0.000
B37.9 Candidiasis, unspecified
0.902 0.098 0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.902 0.098 0.000
E10.0 With coma
0.901 0.099 0.000
M18.1 Other primary arthrosis of first carpometacarpal joint
0.901 0.099 0.000
K73.2 Chronic active hepatitis, not elsewhere classified
0.901 0.099 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.900 0.100 0.000
L94 Other localised connective tissue disorders
0.896 0.104 0.000
C20 Malignant neoplasm of rectum
0.896 0.104 0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral
0.895 0.105 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.895 0.105 0.000
H25-H28 Disorders of lens
0.892 0.108 0.000
M32 Systemic lupus erythematosus
0.890 0.110 0.000
I07.1 Tricuspid insufficiency
0.890 0.110 0.000
N18.0 End-stage renal disease
0.889 0.111 0.000
E07.9 Disorder of thyroid, unspecified
0.888 0.112 0.000
C34.0 Main bronchus
0.887 0.113 0.000
I08 Multiple valve diseases
0.887 0.113 0.000
N05.9 Unspecified
0.886 0.114 0.000
N04.2 Diffuse membranous glomerulonephritis
0.884 0.116 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.884 0.116 0.000
M24.11 Other articular cartilage disorders (Shoulder region)
0.884 0.116 0.000
N25-N29 Other disorders of kidney and ureter
0.883 0.117 0.000
D86 Sarcoidosis
0.882 0.118 0.000
C81.1 Nodular sclerosis
0.881 0.119 0.000
L50-L54 Urticaria and erythema
0.881 0.119 0.000
D55-D59 Haemolytic anaemias
0.880 0.120 0.000
M24.5 Contracture of joint
0.879 0.121 0.000
C81.9 Hodgkin's disease, unspecified
0.877 0.123 0.000
G59.0 Diabetic mononeuropathy
0.876 0.124 0.000
B44 Aspergillosis
0.874 0.126 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.871 0.129 0.000
L92.3 Foreign body granuloma of skin and subcutaneous tissue
0.871 0.129 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.870 0.130 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.870 0.130 0.000
M72 Fibroblastic disorders
0.868 0.132 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.868 0.132 0.000
C34.9 Bronchus or lung, unspecified
0.867 0.133 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.867 0.133 0.000
D69.9 Haemorrhagic condition, unspecified
0.866 0.134 0.000
E53.8 Deficiency of other specified B group vitamins
0.866 0.134 0.000
G70-G73 Diseases of myoneural junction and muscle
0.866 0.134 0.000
D80 Immunodeficiency with predominantly antibody defects
0.865 0.135 0.000
G51 Facial nerve disorders
0.864 0.136 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.864 0.136 0.000
L92.0 Granuloma annulare
0.863 0.137 0.000
M80-M85 Disorders of bone density and structure
0.862 0.138 0.000
H43 Disorders of vitreous body
0.860 0.140 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.854 0.146 0.000
Y42.7 Androgens and anabolic congeners
0.849 0.151 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.847 0.153 0.000
H26 Other cataract
0.846 0.154 0.000
E14.1 With ketoacidosis
0.846 0.154 0.000
B00 Herpesviral [herpes simplex] infections
0.844 0.156 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.842 0.158 0.000
M60-M63 Disorders of muscles
0.842 0.158 0.000
I73.0 Raynaud's syndrome
0.841 0.159 0.000
M15.2 Bouchard's nodes (with arthropathy)
0.840 0.160 0.000
E14.8 With unspecified complications
0.838 0.162 0.000
H43.1 Vitreous haemorrhage
0.837 0.163 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.835 0.165 0.000
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified
0.832 0.168 0.000
Y52 Agents primarily affecting the cardiovascular system
0.831 0.169 0.000
K75.3 Granulomatous hepatitis, not elsewhere classified
0.830 0.170 0.000
N18.2 Chronic kidney disease, stage 2
0.830 0.170 0.000
D73 Diseases of spleen
0.829 0.171 0.000
H05 Disorders of orbit
0.827 0.173 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.826 0.174 0.000
M71 Other bursopathies
0.826 0.174 0.000
V10-V19 Pedal cyclist injured in transport accident
0.825 0.175 0.000
E06.9 Thyroiditis, unspecified
0.825 0.175 0.000
C91.1 Chronic lymphocytic leukaemia
0.825 0.175 0.000
I74.5 Embolism and thrombosis of iliac artery
0.824 0.176 0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)
0.823 0.177 0.000
H30 Chorioretinal inflammation
0.823 0.177 0.000
N05.5 Diffuse mesangiocapillary glomerulonephritis
0.822 0.178 0.000
B25-B34 Other viral diseases
0.821 0.179 0.000
N05.1 Focal and segmental glomerular lesions
0.821 0.179 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.820 0.180 0.000
I11 Hypertensive heart disease
0.820 0.180 0.000
W20-W49 Exposure to inanimate mechanical forces
0.819 0.181 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.817 0.183 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.817 0.183 0.000
E11.6 With other specified complications
0.816 0.184 0.000
D69.4 Other primary thrombocytopenia
0.816 0.184 0.000
E06.3 Autoimmune thyroiditis
0.814 0.186 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.813 0.187 0.000
N04.1 Focal and segmental glomerular lesions
0.813 0.187 0.000
K75.0 Abscess of liver
0.813 0.187 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.812 0.188 0.000
M32.1 Systemic lupus erythematosus with organ or system involvement
0.811 0.189 0.000
L94.9 Localised connective tissue disorder, unspecified
0.810 0.190 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.809 0.191 0.000
M35.7 Hypermobility syndrome
0.809 0.191 0.000
H35 Other retinal disorders
0.808 0.192 0.000
D69.8 Other specified haemorrhagic conditions
0.808 0.192 0.000
C83.7 Burkitt's tumour
0.808 0.192 0.000
G72 Other myopathies
0.807 0.193 0.000
K73.9 Chronic hepatitis, unspecified
0.806 0.194 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.806 0.194 0.000
M33 Dermatopolymyositis
0.806 0.194 0.000
E14.2 Withrenal complications
0.805 0.195 0.000
E10.7 With multiple complications
0.805 0.195 0.000
E07.8 Other specified disorders of thyroid
0.804 0.196 0.000
V20-V29 Motorcycle rider injured in transport accident
0.804 0.196 0.000
L27 Dermatitis due to substances taken internally
0.804 0.196 0.000
N18.1 Chronic kidney disease, stage 1
0.800 0.200 0.000
C88 Malignant immunoproliferative diseases
0.800 0.200 0.000
E10.8 With unspecified complications
0.798 0.202 0.000
H26.9 Cataract, unspecified
0.798 0.202 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.798 0.202 0.000
C23 Malignant neoplasm of gallbladder
0.797 0.203 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.797 0.203 0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]
0.797 0.203 0.000
G56.4 Causalgia
0.796 0.204 0.000
M79.8 Other specified soft tissue disorders
0.796 0.204 0.000
D61.1 Drug-induced aplastic anaemia
0.795 0.205 0.000
E73 Lactose intolerance
0.794 0.206 0.000
G51.9 Disorder of facial nerve, unspecified
0.794 0.206 0.000
M65-M68 Disorders of synovium and tendon
0.794 0.206 0.000
N02 Recurrent and persistent haematuria
0.792 0.207 0.000
Y42.2 Antithyroid drugs
0.792 0.208 0.000
M24.7 Protrusio acetabuli
0.791 0.209 0.000
B37.0 Candidal stomatitis
0.791 0.209 0.000
M76 Enthesopathies of lower limb, excluding foot
0.790 0.209 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.790 0.210 0.000
L89 Decubitus ulcer
0.789 0.211 0.000
H04 Disorders of lachrymal system
0.789 0.211 0.000
G55.2 Nerve root and plexus compressions in spondylosis
0.789 0.211 0.000
D52 Folate deficiency anaemia
0.787 0.213 0.000
V19 Pedal cyclist injured in other and unspecified transport accidents
0.786 0.214 0.000
D83 Common variable immunodeficiency
0.785 0.215 0.000
M24.0 Loose body in joint
0.785 0.215 0.000
D86.9 Sarcoidosis, unspecified
0.785 0.215 0.000
M17.0 Primary gonarthrosis, bilateral
0.784 0.216 0.000
L52 Erythema nodosum
0.784 0.216 0.000
V40-V49 Car occupant injured in transport accident
0.784 0.216 0.000
D69.2 Other nonthrombocytopenic purpura
0.784 0.216 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.784 0.216 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.783 0.217 0.000
E88 Other metabolic disorders
0.783 0.217 0.000
B00.9 Herpesviral infection, unspecified
0.783 0.217 0.000
X20-X29 Contact with venomous animals and plants
0.782 0.218 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.782 0.218 0.000
K72 Hepatic failure, not elsewhere classified
0.781 0.219 0.000
D59 Acquired haemolytic anaemia
0.781 0.219 0.000
M79.7 Fibromyalgia
0.781 0.219 0.000
C38.4 Pleura
0.781 0.219 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.781 0.219 0.000
W50-W64 Exposure to animate mechanical forces
0.779 0.221 0.000
C34.2 Middle lobe, bronchus or lung
0.779 0.221 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.779 0.221 0.000
D51.3 Other dietary vitamin B12 deficiency anaemia
0.778 0.222 0.000
C34.8 Overlapping lesion of bronchus and lung
0.777 0.223 0.000
H46 Optic neuritis
0.777 0.223 0.000
D53 Other nutritional anaemias
0.776 0.224 0.000
L28.1 Prurigo nodularis
0.776 0.224 0.000
D50.1 Sideropenic dysphagia
0.775 0.225 0.000
L93.1 Subacute cutaneous lupus erythematosus
0.775 0.225 0.000
G55.3 Nerve root and plexus compressions in other dorsopathies
0.774 0.226 0.000
B37.7 Candidal septicaemia
0.773 0.227 0.000
N02.2 Diffuse membranous glomerulonephritis
0.772 0.228 0.000
M35.1 Other overlap syndromes
0.772 0.228 0.000
L28.2 Other prurigo
0.768 0.232 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.767 0.233 0.000
L93.2 Other local lupus erythematosus
0.767 0.233 0.000
N18.5 Chronic kidney disease, stage 5
0.767 0.233 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.767 0.233 0.000
C93 Monocytic leukaemia
0.765 0.235 0.000
H35.8 Other specified retinal disorders
0.765 0.235 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.765 0.235 0.000
G56.9 Mononeuropathy of upper limb, unspecified
0.764 0.236 0.000
C83.0 Small cell (diffuse)
0.763 0.237 0.000
K75.9 Inflammatory liver disease, unspecified
0.763 0.237 0.000
E55 Vitamin D deficiency
0.763 0.237 0.000
M20 Acquired deformities of fingers and toes
0.018 0.238 0.744
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.761 0.239 0.000
H26.1 Traumatic cataract
0.761 0.239 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.759 0.241 0.000
A15-A19 Tuberculosis
0.759 0.241 0.000
E31 Polyglandular dysfunction
0.759 0.241 0.000
E61 Deficiency of other nutrient elements
0.758 0.242 0.000
E51 Thiamine deficiency
0.758 0.242 0.000
M24.13 Other articular cartilage disorders (Forearm)
0.756 0.244 0.000
H34.2 Other retinal artery occlusions
0.755 0.245 0.000
C04 Malignant neoplasm of floor of mouth
0.755 0.245 0.000
C22.9 Liver, unspecified
0.754 0.246 0.000
I77.2 Rupture of artery
0.754 0.246 0.000
L84 Corns and callosities
0.753 0.247 0.000
L43.8 Other lichen planus
0.752 0.248 0.000
B02 Zoster [herpes zoster]
0.752 0.248 0.000
B44.9 Aspergillosis, unspecified
0.752 0.248 0.000
M60 Myositis
0.752 0.248 0.000
I73.8 Other specified peripheral vascular diseases
0.749 0.251 0.000
E11.2 With renal complications
0.749 0.251 0.000
D00-D09 In situ neoplasms
0.748 0.252 0.000
K52.3 Indeterminate colitis
0.747 0.253 0.000
G50 Disorders of trigeminal nerve
0.746 0.254 0.000
I00-I02 Acute rheumatic fever
0.744 0.256 0.000
G52 Disorders of other cranial nerves
0.743 0.257 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.743 0.257 0.000
E40-E46 Malnutrition
0.742 0.258 0.000
C02.9 Tongue, unspecified
0.742 0.258 0.000
M34 Systemic sclerosis
0.741 0.259 0.000
L95.8 Other vasculitis limited to skin
0.741 0.259 0.000
H34.1 Central retinal artery occlusion
0.740 0.260 0.000
D86.3 Sarcoidosis of skin
0.740 0.260 0.000
M15.4 Erosive (osteo)arthrosis
0.739 0.261 0.000
H27 Other disorders of lens
0.739 0.261 0.000
K71 Toxic liver disease
0.738 0.262 0.000
B49 Unspecified mycosis
0.737 0.263 0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.737 0.263 0.000
M20.5 Other deformities of toe(s) (acquired)
0.000 0.263 0.737
M86-M90 Other osteopathies
0.737 0.263 0.000
N18.8 Other chronic renal failure
0.737 0.263 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.735 0.265 0.000
C91.9 Lymphoid leukaemia, unspecified
0.735 0.265 0.000
D04 Carcinoma in situ of skin
0.735 0.265 0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)
0.734 0.266 0.000
E14.4 With neurological complications
0.733 0.267 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.733 0.267 0.000
E10.6 With other specified complications
0.733 0.267 0.000
X10-X19 Contact with heat and hot substances
0.732 0.267 0.000
E13 Other specified diabetes mellitus
0.731 0.269 0.000
G30-G32 Other degenerative diseases of the nervous system
0.731 0.269 0.000
C16 Malignant neoplasm of stomach
0.730 0.270 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.730 0.270 0.000
L44 Other papulosquamous disorders
0.730 0.270 0.000
W75-W84 Other accidental threats to breathing
0.730 0.270 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.729 0.271 0.000
I74.8 Embolism and thrombosis of other arteries
0.729 0.271 0.000
G56.1 Other lesions of median nerve
0.729 0.271 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.728 0.272 0.000
M24.17 Other articular cartilage disorders (Ankle and foot)
0.728 0.272 0.000
B25 Cytomegaloviral disease
0.728 0.272 0.000
H04.8 Other disorders of lachrymal system
0.728 0.272 0.000
C91.0 Acute lymphoblastic leukaemia
0.728 0.272 0.000
N03 Chronic nephritic syndrome
0.728 0.272 0.000
B44.1 Other pulmonary aspergillosis
0.727 0.273 0.000
B36 Other superficial mycoses
0.727 0.273 0.000
M24.51 Contracture of joint (Shoulder region)
0.725 0.275 0.000
K74 Fibrosis and cirrhosis of liver
0.724 0.276 0.000
L94.0 Localised scleroderma [morphea]
0.723 0.277 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.722 0.278 0.000
H34.9 Retinal vascular occlusion, unspecified
0.722 0.278 0.000
C81.0 Lymphocytic predominance
0.722 0.278 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.722 0.278 0.000
C15 Malignant neoplasm of oesophagus
0.721 0.279 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.721 0.279 0.000
W45 Foreign body or object entering through skin
0.721 0.279 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.720 0.280 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.720 0.280 0.000
I60-I69 Cerebrovascular diseases
0.719 0.281 0.000
D73.5 Infarction of spleen
0.719 0.281 0.000
D69.5 Secondary thrombocytopenia
0.719 0.281 0.000
H31 Other disorders of choroid
0.719 0.281 0.000
D80.1 Nonfamilial hypogammaglobulinaemia
0.718 0.282 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.717 0.283 0.000
E11.7 With multiple complications
0.717 0.283 0.000
E14.7 With multiple complications
0.717 0.283 0.000
E14.0 With coma
0.717 0.283 0.000
K90.3 Pancreatic steatorrhoea
0.717 0.283 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.717 0.283 0.000
K90.1 Tropical sprue
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.717 0.283 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.717 0.283 0.000
N06 Isolated proteinuria with specified morphological lesion
0.717 0.283 0.000
N01 Rapidly progressive nephritic syndrome
0.717 0.283 0.000
N00 Acute nephritic syndrome
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.717 0.283 0.000
C94 Other leukaemias of specified cell type
0.717 0.283 0.000
C86 Other specified types of T/NK-cell lymphoma
0.717 0.283 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.717 0.283 0.000
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
E03.1 Congenital hypothyroidism without goitre
0.717 0.283 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.717 0.283 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.717 0.283 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.717 0.283 0.000
E16.4 Abnormal secretion of gastrin
0.717 0.283 0.000
E16.3 Increased secretion of glucagon
0.717 0.283 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.717 0.283 0.000
D64.4 Congenital dyserythropoietic anaemia
0.717 0.283 0.000
D64.3 Other sideroblastic anaemias
0.717 0.283 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.717 0.283 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.717 0.283 0.000
D64.0 Hereditary sideroblastic anaemia
0.717 0.283 0.000
K75.2 Nonspecific reactive hepatitis
0.717 0.283 0.000
K75.1 Phlebitis of portal vein
0.717 0.283 0.000
E15 Nondiabetic hypoglycaemic coma
0.717 0.283 0.000
K77 Liver disorders in diseases classified elsewhere
0.717 0.283 0.000
C85.0 Lymphosarcoma
0.717 0.283 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.717 0.283 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.717 0.283 0.000
M35.5 Multifocal fibrosclerosis
0.717 0.283 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.717 0.283 0.000
N04.8 Other
0.717 0.283 0.000
N04.7 Diffuse crescentic glomerulonephritis
0.717 0.283 0.000
N04.6 Dense deposit disease
0.717 0.283 0.000
N04.5 Diffuse mesangiocapillary glomerulonephritis
0.717 0.283 0.000
N04.4 Diffuse endocapillary proliferative glomerulonephritis
0.717 0.283 0.000
N04.3 Diffuse mesangial proliferative glomerulonephritis
0.717 0.283 0.000
N04.0 Minor glomerular abnormality
0.717 0.283 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.716 0.284 0.000
I77.5 Necrosis of artery
0.716 0.284 0.000
I77.4 Coeliac artery compression syndrome
0.716 0.284 0.000
I77.3 Arterial fibromuscular dysplasia
0.716 0.284 0.000
M15.1 Heberden's nodes (with arthropathy)
0.716 0.284 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.716 0.284 0.000
L87 Transepidermal elimination disorders
0.716 0.284 0.000
L86 Keratoderma in diseases classified elsewhere
0.716 0.284 0.000
M24.54 Contracture of joint (Hand)
0.716 0.284 0.000
C81.2 Mixed cellularity
0.716 0.284 0.000
N05.7 Diffuse crescentic glomerulonephritis
0.715 0.285 0.000
N05.6 Dense deposit disease
0.715 0.285 0.000
N05.4 Diffuse endocapillary proliferative glomerulonephritis
0.715 0.285 0.000
N05.3 Diffuse mesangial proliferative glomerulonephritis
0.715 0.285 0.000
N05.0 Minor glomerular abnormality
0.715 0.285 0.000
C83.6 Undifferentiated (diffuse)
0.715 0.285 0.000
C83.5 Lymphoblastic (diffuse)
0.715 0.285 0.000
C83.4 Immunoblastic (diffuse)
0.715 0.285 0.000
C83.2 Mixed small and large cell (diffuse)
0.715 0.285 0.000
I15 Secondary hypertension
0.715 0.285 0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand
0.715 0.285 0.000
I13 Hypertensive heart and renal disease
0.715 0.285 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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