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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3130763
log Bayes Factor = 54.5667
Chromosome 6   position 29,079,156  (GRCh37) Explore rs3130763 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.001 0.999
E10.9 Without complications
0.000 0.001 0.999
E16.2 Hypoglycaemia, unspecified
0.000 0.002 0.998
E10-E14 Diabetes mellitus
0.000 0.002 0.998
E16 Other disorders of pancreatic internal secretion
0.000 0.002 0.998
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.002 0.998
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.002 0.998
E00-E07 Disorders of thyroid gland
0.000 0.003 0.997
E10.3 With ophthalmic complications
0.000 0.011 0.989
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.034 0.966
E10.2 With renal complications
0.000 0.045 0.955
E10.4 With neurological complications
0.000 0.118 0.882
E10.1 With ketoacidosis
0.000 0.138 0.862
E05.8 Other thyrotoxicosis
0.000 0.196 0.804
E16.1 Other hypoglycaemia
0.000 0.205 0.795
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.215 0.784
E13 Other specified diabetes mellitus
0.000 0.229 0.771
E10.7 With multiple complications
0.000 0.246 0.754
E40-E46 Malnutrition
0.000 0.257 0.743
E05.5 Thyroid crisis or storm
0.000 0.283 0.716
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.716
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.716
E12 Malnutrition-related diabetes mellitus
0.000 0.284 0.716
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.284 0.716
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.284 0.716
E16.4 Abnormal secretion of gastrin
0.000 0.284 0.716
E16.3 Increased secretion of glucagon
0.000 0.284 0.716
E15 Nondiabetic hypoglycaemic coma
0.000 0.284 0.715
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.285 0.715
E00 Congenital iodine-deficiency syndrome
0.000 0.285 0.715
E10.0 With coma
0.000 0.288 0.712
E14 Unspecified diabetes mellitus
0.000 0.331 0.669
E07 Other disorders of thyroid
0.000 0.342 0.658
E10.6 With other specified complications
0.000 0.343 0.657
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.358 0.642
E13.9 Without complications
0.000 0.382 0.618
E10.5 With peripheral circulatory complications
0.000 0.387 0.613
E06 Thyroiditis
0.000 0.388 0.612
E03 Other hypothyroidism
0.000 0.397 0.603
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.412 0.587
E14.3 With ophthalmic complications
0.000 0.432 0.568
E46 Unspecified protein-energy malnutrition
0.000 0.439 0.561
E13.8 With unspecified complications
0.000 0.447 0.553
E13.7 With multiple complications
0.000 0.447 0.553
E13.6 With other specified complications
0.000 0.447 0.553
E13.5 With peripheral circulatory complications
0.000 0.447 0.553
E13.4 With neurological complications
0.000 0.447 0.553
E13.2 With renal complications
0.000 0.447 0.553
E13.1 With ketoacidosis
0.000 0.447 0.553
E13.0 With coma
0.000 0.447 0.553
E13.3 With ophthalmic complications
0.000 0.460 0.540
E07.8 Other specified disorders of thyroid
0.000 0.464 0.536
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.535 0.465 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.467 0.533
E45 Retarded development following protein-energy malnutrition
0.000 0.467 0.533
E43 Unspecified severe protein-energy malnutrition
0.000 0.467 0.533
E42 Marasmic kwashiorkor
0.000 0.467 0.533
E41 Nutritional marasmus
0.000 0.467 0.533
E40 Kwashiorkor
0.000 0.467 0.533
E14.1 With ketoacidosis
0.000 0.470 0.530
E10.8 With unspecified complications
0.000 0.471 0.529
E12.9 Without complications
0.000 0.487 0.513
E12.8 With unspecified complications
0.000 0.487 0.513
E12.7 With multiple complications
0.000 0.487 0.513
E12.6 With other specified complications
0.000 0.487 0.513
E12.5 With peripheral circulatory complications
0.000 0.487 0.513
E12.4 With neurological complications
0.000 0.487 0.513
E12.3 With ophthalmic complications
0.000 0.487 0.513
E12.2 With renal complications
0.000 0.487 0.513
E12.1 With ketoacidosis
0.000 0.487 0.513
E12.0 With coma
0.000 0.487 0.513
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.487 0.512
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.487 0.512
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.487 0.512
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.487 0.512
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.487 0.512
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.487 0.512
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.487 0.512
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.487 0.512
E14.8 With unspecified complications
0.000 0.489 0.511
E06.9 Thyroiditis, unspecified
0.000 0.491 0.509
E14.4 With neurological complications
0.000 0.493 0.507
E14.6 With other specified complications
0.000 0.503 0.497
E14.7 With multiple complications
0.000 0.520 0.480
E07.1 Dyshormogenetic goitre
0.000 0.528 0.472
E07.0 Hypersecretion of calcitonin
0.000 0.528 0.472
K90 Intestinal malabsorption
0.000 0.534 0.466
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.540 0.460
E14.5 With peripheral circulatory complications
0.000 0.540 0.460
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.545 0.454
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.545 0.455
E14.0 With coma
0.000 0.548 0.452
E06.1 Subacute thyroiditis
0.000 0.554 0.446
E14.2 Withrenal complications
0.000 0.555 0.444
E06.4 Drug-induced thyroiditis
0.000 0.561 0.439
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.561 0.439
E06.0 Acute thyroiditis
0.000 0.561 0.439
E03.5 Myxoedema coma
0.000 0.567 0.432
E03.4 Atrophy of thyroid (acquired)
0.000 0.567 0.432
E03.3 Postinfectious hypothyroidism
0.000 0.567 0.432
E06.5 Other chronic thyroiditis
0.000 0.575 0.425
E03.1 Congenital hypothyroidism without goitre
0.000 0.579 0.421
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.608 0.392
E44.1 Mild protein-energy malnutrition
0.000 0.618 0.382
E44.0 Moderate protein-energy malnutrition
0.000 0.618 0.382
E65-E68 Obesity and other hyperalimentation
0.000 0.640 0.360
E03.8 Other specified hypothyroidism
0.000 0.642 0.358
E03.9 Hypothyroidism, unspecified
0.000 0.650 0.350
E50-E64 Other nutritional deficiencies
0.000 0.664 0.336
K90.3 Pancreatic steatorrhoea
0.000 0.666 0.334
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.666 0.334
K90.1 Tropical sprue
0.000 0.666 0.334
K90.8 Other intestinal malabsorption
0.000 0.674 0.326
E07.9 Disorder of thyroid, unspecified
0.000 0.712 0.288
R31 Unspecified haematuria
0.277 0.723 0.000
K90.9 Intestinal malabsorption, unspecified
0.000 0.729 0.271
E67 Other hyperalimentation
0.000 0.742 0.258
E68 Sequelae of hyperalimentation
0.000 0.742 0.258
C19 Malignant neoplasm of rectosigmoid junction
0.000 0.747 0.253
E51 Thiamine deficiency
0.000 0.758 0.242
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.759 0.241
E50 Vitamin A deficiency
0.000 0.759 0.241
E60 Dietary zinc deficiency
0.000 0.759 0.241
E59 Dietary selenium deficiency
0.000 0.759 0.241
E52 Niacin deficiency [pellagra]
0.000 0.759 0.241
E54 Ascorbic acid deficiency
0.000 0.763 0.237
E56 Other vitamin deficiencies
0.000 0.771 0.229
E20-E35 Disorders of other endocrine glands
0.000 0.771 0.229
E58 Dietary calcium deficiency
0.000 0.777 0.222
E65 Localised adiposity
0.000 0.780 0.220
E55 Vitamin D deficiency
0.000 0.781 0.219
E63 Other nutritional deficiencies
0.000 0.781 0.219
E24 Cushing's syndrome
0.000 0.787 0.213
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.791 0.209
E61 Deficiency of other nutrient elements
0.000 0.797 0.203
E21.3 Hyperparathyroidism, unspecified
0.000 0.800 0.200
E11 Non-insulin-dependent diabetes mellitus
0.000 0.803 0.197
C15-C26 Malignant neoplasms of digestive organs
0.000 0.805 0.195
C20 Malignant neoplasm of rectum
0.000 0.807 0.193
C15 Malignant neoplasm of oesophagus
0.000 0.809 0.191
E67.8 Other specified hyperalimentation
0.000 0.815 0.185
E67.3 Hypervitaminosis D
0.000 0.815 0.185
E67.2 Megavitamin-B6 syndrome
0.000 0.815 0.185
E67.1 Hypercarotenaemia
0.000 0.815 0.185
E67.0 Hypervitaminosis A
0.000 0.815 0.185
E24.9 Cushing's syndrome, unspecified
0.000 0.816 0.184
E11.6 With other specified complications
0.000 0.818 0.182
E53 Deficiency of other B group vitamins
0.000 0.821 0.179
E24.0 Pituitary-dependent Cushing's disease
0.000 0.822 0.178
C15.5 Lower third of oesophagus
0.000 0.822 0.178
E51.2 Wernicke's encephalopathy
0.000 0.826 0.174
E51.9 Thiamine deficiency, unspecified
0.000 0.826 0.173
E51.8 Other manifestations of thiamine deficiency
0.000 0.826 0.173
E51.1 Beriberi
0.000 0.826 0.173
E50.9 Vitamin A deficiency, unspecified
0.000 0.827 0.173
E50.8 Other manifestations of vitamin A deficiency
0.000 0.827 0.173
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.827 0.173
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.827 0.173
E50.5 Vitamin A deficiency with night blindness
0.000 0.827 0.173
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.827 0.173
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.827 0.173
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.827 0.173
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.827 0.173
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.827 0.173
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.827 0.173
E64.8 Sequelae of other nutritional deficiencies
0.000 0.827 0.173
E64.3 Sequelae of rickets
0.000 0.827 0.173
E64.2 Sequelae of vitamin C deficiency
0.000 0.827 0.173
E64.1 Sequelae of vitamin A deficiency
0.000 0.827 0.173
E64.0 Sequelae of protein-energy malnutrition
0.000 0.827 0.173
C25 Malignant neoplasm of pancreas
0.000 0.831 0.169
E24.2 Drug-induced Cushing's syndrome
0.000 0.832 0.168
E20 Hypoparathyroidism
0.000 0.833 0.167
E56.9 Vitamin deficiency, unspecified
0.000 0.835 0.164
E56.8 Deficiency of other vitamins
0.000 0.835 0.164
E56.0 Deficiency of vitamin E
0.000 0.835 0.164
E06.3 Autoimmune thyroiditis
0.000 0.835 0.164
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.835 0.164
E32 Diseases of thymus
0.000 0.835 0.164
E30 Disorders of puberty, not elsewhere classified
0.000 0.835 0.164
C15.9 Oesophagus, unspecified
0.000 0.836 0.164
E21.4 Other specified disorders of parathyroid gland
0.000 0.836 0.164
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.837 0.163
C15.4 Middle third of oesophagus
0.000 0.838 0.162
E25 Adrenogenital disorders
0.000 0.840 0.160
E31 Polyglandular dysfunction
0.000 0.842 0.158
E55.0 Rickets, active
0.000 0.843 0.157
E63.8 Other specified nutritional deficiencies
0.000 0.843 0.157
E63.1 Imbalance of constituents of food intake
0.000 0.843 0.157
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.843 0.157
M45.X9 Ankylosing spondylitis (Site unspecified)
0.154 0.846 0.000
E24.8 Other Cushing's syndrome
0.000 0.847 0.152
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.847 0.152
E24.3 Ectopic ACTH syndrome
0.000 0.847 0.152
E24.1 Nelson's syndrome
0.000 0.847 0.152
E56.1 Deficiency of vitamin K
0.000 0.847 0.152
E21.2 Other hyperparathyroidism
0.000 0.848 0.152
E11.0 With coma
0.000 0.849 0.151
E11.2 With renal complications
0.000 0.849 0.151
E11.1 With ketoacidosis
0.000 0.853 0.147
C17 Malignant neoplasm of small intestine
0.000 0.854 0.146
E61.9 Deficiency of nutrient element, unspecified
0.000 0.854 0.146
E61.8 Deficiency of other specified nutrient elements
0.000 0.854 0.146
E61.7 Deficiency of multiple nutrient elements
0.000 0.854 0.146
E61.6 Vanadium deficiency
0.000 0.854 0.146
E61.5 Molybdenum deficiency
0.000 0.854 0.146
E61.4 Chromium deficiency
0.000 0.854 0.146
E61.3 Manganese deficiency
0.000 0.854 0.146
E61.0 Copper deficiency
0.000 0.854 0.146
C25.1 Body of pancreas
0.000 0.856 0.144
C15.0 Cervical part of oesophagus
0.000 0.856 0.143
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.000 0.857 0.143
E83 Disorders of mineral metabolism
0.135 0.858 0.008
E28 Ovarian dysfunction
0.000 0.858 0.142
C25.3 Pancreatic duct
0.000 0.858 0.142
E11.7 With multiple complications
0.000 0.858 0.141
E53.9 Vitamin B deficiency, unspecified
0.000 0.861 0.139
C25.2 Tail of pancreas
0.000 0.861 0.139
C15.8 Overlapping lesion of oesophagus
0.000 0.863 0.137
C15.2 Abdominal part of oesophagus
0.000 0.863 0.137
C17.0 Duodenum
0.000 0.864 0.136
E29 Testicular dysfunction
0.000 0.865 0.135
E63.9 Nutritional deficiency, unspecified
0.000 0.865 0.134
E55.9 Vitamin D deficiency, unspecified
0.000 0.865 0.135
C15.1 Thoracic part of oesophagus
0.000 0.866 0.134
E61.1 Iron deficiency
0.000 0.867 0.133
C25.4 Endocrine pancreas
0.000 0.868 0.132
E53.1 Pyridoxine deficiency
0.000 0.871 0.128
E53.0 Riboflavin deficiency
0.000 0.871 0.128
C24.0 Extrahepatic bile duct
0.000 0.872 0.128
C25.8 Overlapping lesion of pancreas
0.000 0.872 0.128
E34 Other endocrine disorders
0.000 0.873 0.127
C15.3 Upper third of oesophagus
0.000 0.875 0.125
E61.2 Magnesium deficiency
0.000 0.875 0.125
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.875 0.124
E20.9 Hypoparathyroidism, unspecified
0.000 0.878 0.122
E20.8 Other hypoparathyroidism
0.000 0.880 0.120
E20.1 Pseudohypoparathyroidism
0.000 0.880 0.120
E20.0 Idiopathic hypoparathyroidism
0.000 0.880 0.120
E30.9 Disorder of puberty, unspecified
0.000 0.882 0.118
E30.8 Other disorders of puberty
0.000 0.882 0.118
E30.1 Precocious puberty
0.000 0.882 0.118
E30.0 Delayed puberty
0.000 0.882 0.118
E32.9 Disease of thymus, unspecified
0.000 0.882 0.118
E32.8 Other diseases of thymus
0.000 0.882 0.118
E32.1 Abscess of thymus
0.000 0.882 0.118
E32.0 Persistent hyperplasia of thymus
0.000 0.882 0.118
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.882 0.118
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.882 0.118
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.882 0.118
C25.9 Pancreas, unspecified
0.000 0.882 0.118
E11.8 With unspecified complications
0.000 0.883 0.117
E25.9 Adrenogenital disorder, unspecified
0.000 0.885 0.115
E25.8 Other adrenogenital disorders
0.000 0.885 0.115
E83.3 Disorders of phosphorus metabolism
0.113 0.885 0.002
E31.9 Polyglandular dysfunction, unspecified
0.000 0.887 0.113
E31.8 Other polyglandular dysfunction
0.000 0.887 0.113
E31.1 Polyglandular hyperfunction
0.000 0.887 0.113
C21 Malignant neoplasm of anus and anal canal
0.000 0.887 0.113
C25.7 Other parts of pancreas
0.000 0.888 0.112
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.889 0.111
E26 Hyperaldosteronism
0.000 0.891 0.109
E31.0 Autoimmune polyglandular failure
0.000 0.893 0.106
C17.8 Overlapping lesion of small intestine
0.000 0.895 0.105
C17.3 Meckel's diverticulum
0.000 0.895 0.105
E21.0 Primary hyperparathyroidism
0.000 0.895 0.105
C24.8 Overlapping lesion of biliary tract
0.000 0.897 0.103
E83.8 Other disorders of mineral metabolism
0.097 0.898 0.006
E83.2 Disorders of zinc metabolism
0.097 0.898 0.006
E83.0 Disorders of copper metabolism
0.097 0.898 0.006
I83 Varicose veins of lower extremities
0.102 0.898 0.000
E28.9 Ovarian dysfunction, unspecified
0.000 0.898 0.102
E28.8 Other ovarian dysfunction
0.000 0.898 0.102
E28.1 Androgen excess
0.000 0.898 0.102
E28.0 Oestrogen excess
0.000 0.898 0.102
E83.9 Disorder of mineral metabolism, unspecified
0.096 0.899 0.006
C17.1 Jejunum
0.000 0.900 0.099
C24.9 Biliary tract, unspecified
0.000 0.901 0.099
E29.9 Testicular dysfunction, unspecified
0.000 0.903 0.097
E29.8 Other testicular dysfunction
0.000 0.903 0.097
E29.0 Testicular hyperfunction
0.000 0.903 0.097
E28.2 Polycystic ovarian syndrome
0.000 0.904 0.096
C26 Malignant neoplasm of other and ill-defined digestive organs
0.000 0.905 0.095
E22 Hyperfunction of pituitary gland
0.000 0.906 0.094
E34.3 Short stature, not elsewhere classified
0.000 0.907 0.093
S02.40 Fracture of malar and maxillary bones (closed)
0.000 0.908 0.092
E34.5 Androgen resistance syndrome
0.000 0.908 0.091
E34.4 Constitutional tall stature
0.000 0.908 0.091
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.908 0.091
E34.1 Other hypersecretion of intestinal hormones
0.000 0.908 0.091
C23 Malignant neoplasm of gallbladder
0.000 0.909 0.091
C21.8 Overlapping lesion of rectum, anus and anal canal
0.000 0.911 0.089
E28.3 Primary ovarian failure
0.000 0.913 0.087
E34.9 Endocrine disorder, unspecified
0.000 0.916 0.084
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.000 0.917 0.083
C21.2 Cloacogenic zone
0.000 0.919 0.081
S02.4 Fracture of malar and maxillary bones
0.000 0.919 0.081
E34.8 Other specified endocrine disorders
0.000 0.920 0.080
E26.8 Other hyperaldosteronism
0.000 0.921 0.078
E26.1 Secondary hyperaldosteronism
0.000 0.921 0.078
E34.0 Carcinoid syndrome
0.000 0.921 0.078
E11.3 With ophthalmic complications
0.000 0.922 0.078
C17.9 Small intestine, unspecified
0.000 0.922 0.077
S02 Fracture of skull and facial bones
0.000 0.926 0.074
C18 Malignant neoplasm of colon
0.000 0.927 0.073
E11.5 With peripheral circulatory complications
0.000 0.927 0.073
C18.9 Colon, unspecified
0.000 0.928 0.072
I83.0 Varicose veins of lower extremities with ulcer
0.071 0.929 0.000
E26.9 Hyperaldosteronism, unspecified
0.001 0.930 0.069
C17.2 Ileum
0.000 0.931 0.069
C18.1 Appendix
0.000 0.931 0.069
C26.8 Overlapping lesion of digestive system
0.000 0.931 0.068
C26.1 Spleen
0.000 0.931 0.068
E29.1 Testicular hypofunction
0.000 0.932 0.068
E22.8 Other hyperfunction of pituitary gland
0.000 0.933 0.067
M45 Ankylosing spondylitis
0.067 0.933 0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.067 0.933 0.000
S02.0 Fracture of vault of skull
0.000 0.933 0.067
E22.1 Hyperprolactinaemia
0.000 0.934 0.066
C21.0 Anus, unspecified
0.000 0.934 0.066
S02.8 Fractures of other skull and facial bones
0.000 0.935 0.065
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.936 0.063
S02.00 Fracture of vault of skull (closed)
0.000 0.938 0.062
C22.9 Liver, unspecified
0.000 0.938 0.061
C21.1 Anal canal
0.000 0.939 0.061
S02.3 Fracture of orbital floor
0.000 0.939 0.060
E14.9 Without complications
0.000 0.940 0.060
E23 Hypofunction and other disorders of pituitary gland
0.000 0.940 0.060
C22.7 Other specified carcinomas of liver
0.000 0.940 0.059
C22.4 Other sarcomas of liver
0.000 0.940 0.059
C22.3 Angiosarcoma of liver
0.000 0.940 0.059
C22.2 Hepatoblastoma
0.000 0.940 0.059
S02.6 Fracture of mandible
0.000 0.942 0.058
S02.80 Fractures of other skull and facial bones (closed)
0.000 0.942 0.058
S02.7 Multiple fractures involving skull and facial bones
0.000 0.942 0.057
S02.5 Fracture of tooth
0.000 0.943 0.057
C25.0 Head of pancreas
0.000 0.944 0.056
C18.8 Overlapping lesion of colon
0.000 0.944 0.056
S02.41 Fracture of malar and maxillary bones (open)
0.000 0.946 0.054
M45.X2 Ankylosing spondylitis (Cervical region)
0.054 0.946 0.000
C26.9 Ill-defined sites within the digestive system
0.000 0.947 0.053
C24.1 Ampulla of Vater
0.001 0.947 0.052
S02.30 Fracture of orbital floor (closed)
0.000 0.949 0.051
C18.4 Transverse colon
0.000 0.949 0.051
S02.9 Fracture of skull and facial bones, part unspecified
0.000 0.949 0.051
S02.2 Fracture of nasal bones
0.000 0.950 0.050
C22.1 Intrahepatic bile duct carcinoma
0.000 0.950 0.050
C26.0 Intestinal tract, part unspecified
0.000 0.950 0.050
M45.X6 Ankylosing spondylitis (Lumbar region)
0.049 0.950 0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.048 0.952 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.048 0.952 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.048 0.952 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.048 0.952 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.048 0.952 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.048 0.952 0.000
S02.01 Fracture of vault of skull (open)
0.000 0.952 0.048
E23.7 Disorder of pituitary gland, unspecified
0.000 0.952 0.047
E22.0 Acromegaly and pituitary gigantism
0.000 0.953 0.047
S02.60 Fracture of mandible (closed)
0.000 0.953 0.047
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.953 0.047
S02.81 Fractures of other skull and facial bones (open)
0.000 0.953 0.046
S02.70 Multiple fractures involving skull and facial bones (closed)
0.000 0.954 0.046
S02.50 Fracture of tooth (closed)
0.000 0.955 0.045
E04 Other non-toxic goitre
0.003 0.955 0.042
E83.4 Disorders of magnesium metabolism
0.041 0.955 0.004
S02.31 Fracture of orbital floor (open)
0.000 0.956 0.043
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.957 0.043
E23.1 Drug-induced hypopituitarism
0.000 0.957 0.043
S02.1 Fracture of base of skull
0.000 0.957 0.043
E11.4 With neurological complications
0.000 0.957 0.042
E26.0 Primary hyperaldosteronism
0.001 0.958 0.042
S02.61 Fracture of mandible (open)
0.000 0.958 0.042
E27 Other disorders of adrenal gland
0.000 0.958 0.042
S02.71 Multiple fractures involving skull and facial bones (open)
0.000 0.958 0.041
S02.51 Fracture of tooth (open)
0.000 0.959 0.041
S02.21 Fracture of nasal bones (open)
0.000 0.959 0.040
E70-E90 Metabolic disorders
0.002 0.960 0.038
C18.6 Descending colon
0.000 0.960 0.040
C18.7 Sigmoid colon
0.000 0.962 0.038
C16 Malignant neoplasm of stomach
0.000 0.962 0.037
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.037 0.963 0.000
S02.91 Fracture of skull and facial bones, part unspecified (open)
0.000 0.963 0.036
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.964 0.036
E53.8 Deficiency of other specified B group vitamins
0.000 0.964 0.036
E78.2 Mixed hyperlipidaemia
0.000 0.965 0.035
E78.5 Hyperlipidaemia, unspecified
0.000 0.965 0.035
S02.90 Fracture of skull and facial bones, part unspecified (closed)
0.000 0.966 0.034
C18.3 Hepatic flexure
0.000 0.966 0.034
Z71.8 Other specified counselling
0.033 0.967 0.000
E04.8 Other specified non-toxic goitre
0.002 0.968 0.030
E27.1 Primary adrenocortical insufficiency
0.000 0.969 0.031
E73 Lactose intolerance
0.001 0.969 0.030
E78.1 Pure hyperglyceridaemia
0.000 0.969 0.031
E27.5 Adrenomedullary hyperfunction
0.000 0.970 0.030
E27.0 Other adrenocortical overactivity
0.000 0.970 0.030
E11.9 Without complications
0.000 0.970 0.030
S02.11 Fracture of base of skull (open)
0.000 0.970 0.030
I77 Other disorders of arteries and arterioles
0.000 0.971 0.029
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.001 0.971 0.028
E74 Other disorders of carbohydrate metabolism
0.001 0.971 0.028
E77 Disorders of glycoprotein metabolism
0.001 0.971 0.028
E76 Disorders of glycosaminoglycan metabolism
0.001 0.971 0.028
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.001 0.971 0.028
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.001 0.971 0.028
E78.6 Lipoprotein deficiency
0.000 0.971 0.029
E23.6 Other disorders of pituitary gland
0.001 0.971 0.028
I83.1 Varicose veins of lower extremities with inflammation
0.029 0.971 0.000
I77.6 Arteritis, unspecified
0.000 0.971 0.029
K90-K93 Other diseases of the digestive system
0.000 0.971 0.028
E85 Amyloidosis
0.001 0.972 0.027
E70 Disorders of aromatic amino-acid metabolism
0.001 0.972 0.026
E88 Other metabolic disorders
0.001 0.972 0.027
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.973 0.027
E66 Obesity
0.000 0.973 0.027
E78.3 Hyperchylomicronaemia
0.000 0.973 0.027
E27.9 Disorder of adrenal gland, unspecified
0.000 0.973 0.027
E72 Other disorders of amino-acid metabolism
0.001 0.973 0.025
E79 Disorders of purine and pyrimidine metabolism
0.001 0.973 0.025
I77.8 Other specified disorders of arteries and arterioles
0.000 0.973 0.027
I77.1 Stricture of artery
0.000 0.974 0.026
C16.5 Lesser curvature of stomach, unspecified
0.000 0.974 0.026
E23.2 Diabetes insipidus
0.000 0.974 0.026
S02.20 Fracture of nasal bones (closed)
0.000 0.974 0.026
E84 Cystic fibrosis
0.001 0.974 0.024
E27.2 Addisonian crisis
0.000 0.974 0.026
C16.2 Body of stomach
0.000 0.975 0.025
E73.9 Lactose intolerance, unspecified
0.000 0.975 0.024
C16.6 Greater curvature of stomach, unspecified
0.000 0.975 0.025
C16.8 Overlapping lesion of stomach
0.000 0.976 0.024
C16.4 Pylorus
0.000 0.976 0.024
E78.4 Other hyperlipidaemia
0.000 0.976 0.024
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.976 0.023
C16.9 Stomach, unspecified
0.000 0.977 0.023
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.977 0.023
E88.9 Metabolic disorder, unspecified
0.000 0.977 0.023
I73 Other peripheral vascular diseases
0.000 0.977 0.023
I73.9 Peripheral vascular disease, unspecified
0.000 0.977 0.023
C16.1 Fundus of stomach
0.000 0.977 0.022
C16.0 Cardia
0.000 0.977 0.023
E73.8 Other lactose intolerance
0.001 0.977 0.022
E73.1 Secondary lactase deficiency
0.001 0.977 0.022
E73.0 Congenital lactase deficiency
0.001 0.977 0.022
E85.4 Organ-limited amyloidosis
0.001 0.977 0.022
I74 Arterial embolism and thrombosis
0.000 0.977 0.023
E04.0 Non-toxic diffuse goitre
0.003 0.978 0.020
E75.5 Other lipid storage disorders
0.001 0.978 0.021
I77.2 Rupture of artery
0.000 0.978 0.022
S02.10 Fracture of base of skull (closed)
0.000 0.978 0.022
I77.3 Arterial fibromuscular dysplasia
0.000 0.978 0.022
E74.3 Other disorders of intestinal carbohydrate absorption
0.001 0.978 0.021
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.978 0.022
C16.3 Pyloric antrum
0.000 0.978 0.021
I77.5 Necrosis of artery
0.000 0.979 0.021
I77.4 Coeliac artery compression syndrome
0.000 0.979 0.021
E75.6 Lipid storage disorder, unspecified
0.001 0.979 0.020
E75.4 Neuronal ceroid lipofuscinosis
0.001 0.979 0.020
E75.3 Sphingolipidosis, unspecified
0.001 0.979 0.020
E75.1 Other gangliosidosis
0.001 0.979 0.020
E75.0 GM2 gangliosidosis
0.001 0.979 0.020
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.979 0.021
E74.9 Disorder of carbohydrate metabolism, unspecified
0.001 0.979 0.020
E74.8 Other specified disorders of carbohydrate metabolism
0.001 0.979 0.020
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.001 0.979 0.020
E74.2 Disorders of galactose metabolism
0.001 0.979 0.020
E74.1 Disorders of fructose metabolism
0.001 0.979 0.020
E71.3 Disorders of fatty-acid metabolism
0.001 0.979 0.020
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.001 0.979 0.020
E71.1 Other disorders of branched-chain amino-acid metabolism
0.001 0.979 0.020
E71.0 Maple-syrup-urine disease
0.001 0.979 0.020
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.001 0.979 0.020
E76.8 Other disorders of glucosaminoglycan metabolism
0.001 0.979 0.020
E76.3 Mucopolysaccharidosis, unspecified
0.001 0.979 0.020
E76.2 Other mucopolysaccharidoses
0.001 0.979 0.020
E76.1 Mucopolysaccharidosis, type II
0.001 0.979 0.020
E76.0 Mucopolysaccharidosis, type I
0.001 0.979 0.020
E77.9 Disorder of glycoprotein metabolism, unspecified
0.001 0.979 0.020
E77.8 Other disorders of glycoprotein metabolism
0.001 0.979 0.020
E77.1 Defects in glycoprotein degradation
0.001 0.979 0.020
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.001 0.979 0.020
E75.2 Other sphingolipidosis
0.001 0.979 0.020
I74.5 Embolism and thrombosis of iliac artery
0.000 0.979 0.021
E85.3 Secondary systemic amyloidosis
0.001 0.979 0.020
E88.2 Lipomatosis, not elsewhere classified
0.000 0.979 0.020
C18.5 Splenic flexure
0.000 0.979 0.020
E88.1 Lipodystrophy, not elsewhere classified
0.001 0.979 0.020
E74.0 Glycogen storage disease
0.001 0.979 0.020
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.979 0.020
E85.8 Other amyloidosis
0.001 0.980 0.020
E85.2 Heredofamilial amyloidosis, unspecified
0.001 0.980 0.020
E85.1 Neuropathic heredofamilial amyloidosis
0.001 0.980 0.020
E85.0 Nonneuropathic heredofamilial amyloidosis
0.001 0.980 0.020
S00-S09 Injuries to the head
0.000 0.980 0.020
C22.0 Liver cell carcinoma
0.001 0.980 0.020
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.001 0.980 0.019
E70.8 Other disorders of aromatic amino-acid metabolism
0.001 0.980 0.019
E70.2 Disorders of tyrosine metabolism
0.001 0.980 0.019

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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