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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3130933
log Bayes Factor = 63.7387
Chromosome 6   position 31,132,085  (GRCh37) Explore rs3130933 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
E78.0 Pure hypercholesterolaemia
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
I25.1 Atherosclerotic heart disease
0.000 0.000 1.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.001 0.999
E11 Non-insulin-dependent diabetes mellitus
0.000 0.002 0.998
E10.3 With ophthalmic complications
0.000 0.002 0.998
E14 Unspecified diabetes mellitus
0.000 0.003 0.997
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.003 0.997
E11.9 Without complications
0.000 0.003 0.997
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.004 0.996
E70-E90 Metabolic disorders
0.000 0.004 0.996
I25.2 Old myocardial infarction
0.000 0.005 0.995
E14.9 Without complications
0.000 0.007 0.993
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.010 0.990
I10 Essential (primary) hypertension
0.000 0.012 0.988
I10-I15 Hypertensive diseases
0.000 0.014 0.986
I21 Acute myocardial infarction
0.000 0.022 0.978
Chapter IX Diseases of the circulatory system
0.000 0.030 0.970
I20 Angina pectoris
0.000 0.032 0.968
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.038 0.962
I25.5 Ischaemic cardiomyopathy
0.000 0.041 0.959
J45.9 Asthma, unspecified
0.000 0.041 0.959
I24 Other acute ischaemic heart diseases
0.000 0.043 0.957
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.045 0.955
I20.9 Angina pectoris, unspecified
0.000 0.052 0.948
I12 Hypertensive renal disease
0.000 0.052 0.948
I21.9 Acute myocardial infarction, unspecified
0.000 0.061 0.939
E05.9 Thyrotoxicosis, unspecified
0.000 0.061 0.939
I22 Subsequent myocardial infarction
0.000 0.066 0.934
L40-L45 Papulosquamous disorders
0.000 0.067 0.933
E10.1 With ketoacidosis
0.000 0.069 0.931
M06 Other rheumatoid arthritis
0.000 0.086 0.914
E78.2 Mixed hyperlipidaemia
0.000 0.089 0.911
I12.9 Hypertensive renal disease without renal failure
0.000 0.100 0.900
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.102 0.898
L40.0 Psoriasis vulgaris
0.000 0.103 0.897
E78.8 Other disorders of lipoprotein metabolism
0.000 0.106 0.894
E78.5 Hyperlipidaemia, unspecified
0.000 0.108 0.892
E11.0 With coma
0.000 0.113 0.887
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.115 0.885
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.115 0.885
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.120 0.880
E10.4 With neurological complications
0.000 0.120 0.880
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.124 0.876
L43 Lichen planus
0.000 0.124 0.876
E11.1 With ketoacidosis
0.000 0.125 0.875
I21.4 Acute subendocardial myocardial infarction
0.000 0.126 0.874
E14.3 With ophthalmic complications
0.000 0.126 0.874
I20.0 Unstable angina
0.000 0.148 0.852
E10.8 With unspecified complications
0.000 0.154 0.846
M05-M14 Inflammatory polyarthropathies
0.000 0.154 0.846
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.158 0.842
G35-G37 Demyelinating diseases of the central nervous system
0.841 0.159 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.166 0.834
I15 Secondary hypertension
0.000 0.166 0.834
L43.9 Lichen planus, unspecified
0.000 0.169 0.831
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.169 0.831
L40.8 Other psoriasis
0.000 0.176 0.824
I24.8 Other forms of acute ischaemic heart disease
0.000 0.180 0.820
M45 Ankylosing spondylitis
0.000 0.180 0.820
E13 Other specified diabetes mellitus
0.000 0.180 0.820
E74 Other disorders of carbohydrate metabolism
0.000 0.181 0.819
E10.2 With renal complications
0.000 0.181 0.819
E10.0 With coma
0.000 0.196 0.804
M07 Psoriatic and enteropathic arthropathies
0.000 0.197 0.803
M70-M79 Other soft tissue disorders
0.000 0.198 0.802
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.199 0.801
M45-M49 Spondylopathies
0.000 0.201 0.799
I12.0 Hypertensive renal disease with renal failure
0.000 0.202 0.798
M79 Other soft tissue disorders, not elsewhere classified
0.000 0.204 0.796
M79.6 Pain in limb
0.000 0.206 0.794
E11.2 With renal complications
0.000 0.211 0.789
G37 Other demyelinating diseases of central nervous system
0.787 0.213 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.213 0.786
M79.65 Pain in limb (Pelvic region and thigh)
0.000 0.219 0.781
M75 Shoulder lesions
0.000 0.221 0.779
E07 Other disorders of thyroid
0.000 0.222 0.778
M75.0 Adhesive capsulitis of shoulder
0.000 0.223 0.777
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.223 0.777
M07.3 Other psoriatic arthropathies
0.000 0.227 0.773
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.228 0.772
M06.3 Rheumatoid nodule
0.000 0.230 0.770
I25.3 Aneurysm of heart
0.000 0.231 0.769
M79.7 Fibromyalgia
0.000 0.240 0.760
E40-E46 Malnutrition
0.000 0.241 0.759
M79.67 Pain in limb (Ankle and foot)
0.000 0.247 0.753
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.250 0.750
E78.1 Pure hyperglyceridaemia
0.000 0.257 0.743
M79.79 Fibromyalgia (Site unspecified)
0.000 0.258 0.742
E85 Amyloidosis
0.000 0.258 0.742
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.260 0.740
G37.9 Demyelinating disease of central nervous system, unspecified
0.736 0.264 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.735 0.265 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.267 0.733
E78.4 Other hyperlipidaemia
0.000 0.268 0.732
E14.4 With neurological complications
0.000 0.269 0.731
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.270 0.730
E10.6 With other specified complications
0.000 0.273 0.727
E10.5 With peripheral circulatory complications
0.000 0.275 0.725
M79.62 Pain in limb (Upper arm)
0.000 0.278 0.722
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.279 0.720
# Top node
0.000 0.280 0.720
E10.7 With multiple complications
0.000 0.283 0.717
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.3 Pustulosis palmaris et plantaris
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.283 0.717
I23 Certain current complications following acute myocardial infarction
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E78.6 Lipoprotein deficiency
0.000 0.283 0.717
E78.3 Hyperchylomicronaemia
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.284 0.716
E03.8 Other specified hypothyroidism
0.000 0.284 0.716
E14.8 With unspecified complications
0.000 0.285 0.715
E14.7 With multiple complications
0.000 0.285 0.715
E14.6 With other specified complications
0.000 0.285 0.715
E14.5 With peripheral circulatory complications
0.000 0.285 0.715
E14.2 Withrenal complications
0.000 0.285 0.715
E14.1 With ketoacidosis
0.000 0.285 0.715
E14.0 With coma
0.000 0.285 0.715
E79 Disorders of purine and pyrimidine metabolism
0.000 0.286 0.714
E77 Disorders of glycoprotein metabolism
0.000 0.286 0.714
E76 Disorders of glycosaminoglycan metabolism
0.000 0.286 0.714
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.286 0.714
E72 Other disorders of amino-acid metabolism
0.000 0.286 0.714
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.286 0.714
E70 Disorders of aromatic amino-acid metabolism
0.000 0.286 0.714
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.286 0.714
I13 Hypertensive heart and renal disease
0.000 0.293 0.707
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.293 0.707
M79.1 Myalgia
0.000 0.293 0.707
E20-E35 Disorders of other endocrine glands
0.000 0.294 0.706
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.298 0.702
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.299 0.701
E11.6 With other specified complications
0.000 0.299 0.701
I00-I02 Acute rheumatic fever
0.000 0.304 0.696
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.308 0.692
L42 Pityriasis rosea
0.000 0.308 0.692
E13.9 Without complications
0.000 0.309 0.691
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.310 0.690
I15.1 Hypertension secondary to other renal disorders
0.000 0.312 0.688
M06.4 Inflammatory polyarthropathy
0.000 0.313 0.687
M75.4 Impingement syndrome of shoulder
0.000 0.314 0.686
E05.5 Thyroid crisis or storm
0.000 0.315 0.685
E05.4 Thyrotoxicosis factitia
0.000 0.315 0.685
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.315 0.685
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.315 0.685
E11.5 With peripheral circulatory complications
0.000 0.316 0.684
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.321 0.679
E84 Cystic fibrosis
0.000 0.323 0.677
I83 Varicose veins of lower extremities
0.668 0.324 0.008
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.325 0.675
L44 Other papulosquamous disorders
0.000 0.331 0.669
L41 Parapsoriasis
0.000 0.331 0.669
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.331 0.669
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.334 0.666
E50-E64 Other nutritional deficiencies
0.000 0.337 0.663
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.338 0.662
E05.8 Other thyrotoxicosis
0.000 0.344 0.656
I15.9 Seconday hypertension, unspecified
0.000 0.344 0.656
M06.8 Other specified rheumatoid arthritis
0.000 0.345 0.655
M06.2 Rheumatoid bursitis
0.000 0.345 0.655
M06.1 Adult-onset Still's disease
0.000 0.345 0.655
M70 Soft tissue disorders related to use, overuse and pressure
0.000 0.346 0.654
M05 Seropositive rheumatoid arthritis
0.000 0.347 0.653
L43.8 Other lichen planus
0.000 0.353 0.647
M79.18 Myalgia (Other)
0.000 0.353 0.647
Chapter VIII Diseases of the ear and mastoid process
0.000 0.355 0.645
M06.34 Rheumatoid nodule (Hand)
0.000 0.358 0.642
I22.8 Subsequent myocardial infarction of other sites
0.000 0.359 0.641
G37.8 Other specified demyelinating diseases of central nervous system
0.639 0.361 0.000
E07.9 Disorder of thyroid, unspecified
0.000 0.363 0.637
I11 Hypertensive heart disease
0.000 0.364 0.636
E16 Other disorders of pancreatic internal secretion
0.000 0.366 0.633
M77 Other enthesopathies
0.000 0.369 0.631
I83.0 Varicose veins of lower extremities with ulcer
0.627 0.371 0.002
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.372 0.628
L43.3 Subacute (active) lichen planus
0.000 0.372 0.628
L43.2 Lichenoid drug reaction
0.000 0.372 0.628
L43.1 Bullous lichen planus
0.000 0.372 0.628
L43.0 Hypertrophic lichen planus
0.000 0.372 0.628
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.374 0.626
I30-I52 Other forms of heart disease
0.000 0.374 0.626
E83 Disorders of mineral metabolism
0.323 0.375 0.302
I24.1 Dressler's syndrome
0.000 0.376 0.624
E11.4 With neurological complications
0.000 0.379 0.621
M75.2 Bicipital tendinitis
0.000 0.382 0.618
M49 Spondylopathies in diseases classified elsewhere
0.000 0.383 0.617
H60-H62 Diseases of external ear
0.000 0.383 0.617
E73 Lactose intolerance
0.000 0.387 0.612
M79.60 Pain in limb (Multiple sites)
0.000 0.389 0.611
M79.64 Pain in limb (Hand)
0.000 0.389 0.611
E11.8 With unspecified complications
0.000 0.391 0.609
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.392 0.608
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.394 0.606
M08 Juvenile arthritis
0.000 0.394 0.606
G36 Other acute disseminated demyelination
0.603 0.397 0.000
I46 Cardiac arrest
0.000 0.399 0.601
I15.8 Other secondary hypertension
0.000 0.402 0.598
I15.2 Hypertension secondary to endocrine disorders
0.000 0.402 0.598
I15.0 Renovascular hypertension
0.000 0.402 0.598
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.405 0.595
M11 Other crystal arthropathies
0.000 0.406 0.594
E28 Ovarian dysfunction
0.000 0.406 0.594
E89.3 Postprocedural hypopituitarism
0.000 0.407 0.593
E23 Hypofunction and other disorders of pituitary gland
0.000 0.409 0.591
I46.9 Cardiac arrest, unspecified
0.000 0.409 0.591
I44 Atrioventricular and left bundle-branch block
0.000 0.409 0.591
I51 Complications and ill-defined descriptions of heart disease
0.000 0.410 0.590
H60 Otitis externa
0.000 0.411 0.589
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.412 0.588
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.412 0.588
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.412 0.588
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.412 0.588
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.412 0.588
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.412 0.588
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.412 0.588
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.412 0.588
E13.8 With unspecified complications
0.000 0.412 0.588
E13.7 With multiple complications
0.000 0.412 0.588
E13.6 With other specified complications
0.000 0.412 0.588
E13.5 With peripheral circulatory complications
0.000 0.412 0.588
E13.4 With neurological complications
0.000 0.412 0.588
E13.3 With ophthalmic complications
0.000 0.412 0.588
E13.2 With renal complications
0.000 0.412 0.588
E13.1 With ketoacidosis
0.000 0.412 0.588
E13.0 With coma
0.000 0.412 0.588
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.413 0.587
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.413 0.587
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.413 0.587
E74.2 Disorders of galactose metabolism
0.000 0.413 0.587
E74.1 Disorders of fructose metabolism
0.000 0.413 0.587
E74.0 Glycogen storage disease
0.000 0.413 0.587
E46 Unspecified protein-energy malnutrition
0.000 0.413 0.587
H65-H75 Diseases of middle ear and mastoid
0.000 0.422 0.578
M79.9 Soft tissue disorder, unspecified
0.000 0.423 0.577
E24 Cushing's syndrome
0.000 0.423 0.577
M07.6 Other enteropathic arthropathies
0.000 0.424 0.576
M07.5 Arthropathy in ulcerative colitis
0.000 0.424 0.576
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.424 0.576
M07.2 Psoriatic spondylitis
0.000 0.424 0.576
M07.1 Arthritis mutilans
0.000 0.424 0.576
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.424 0.576
M73 Soft tissue disorders in diseases classified elsewhere
0.000 0.425 0.575
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.426 0.574
I51.8 Other ill-defined heart diseases
0.000 0.427 0.573
E85.9 Amyloidosis, unspecified
0.000 0.427 0.573
M79.3 Panniculitis, unspecified
0.000 0.429 0.571
E61 Deficiency of other nutrient elements
0.000 0.430 0.570
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.430 0.570
I25.4 Coronary artery aneurysm
0.000 0.433 0.567
E85.4 Organ-limited amyloidosis
0.000 0.434 0.565
M77.1 Lateral epicondylitis
0.000 0.435 0.565
G37.5 Concentric sclerosis [Balo]
0.564 0.436 0.000
G37.4 Subacute necrotising myelitis
0.564 0.436 0.000
G37.2 Central pontine myelinolysis
0.564 0.436 0.000
G37.1 Central demyelination of corpus callosum
0.564 0.436 0.000
G37.0 Diffuse sclerosis
0.564 0.436 0.000
E15 Nondiabetic hypoglycaemic coma
0.000 0.436 0.564
M70.4 Prepatellar bursitis
0.000 0.441 0.559
M75.8 Other shoulder lesions
0.000 0.442 0.558
H60.9 Otitis externa, unspecified
0.000 0.442 0.558
E07.1 Dyshormogenetic goitre
0.000 0.442 0.557
E07.0 Hypersecretion of calcitonin
0.000 0.442 0.557
I20.1 Angina pectoris with documented spasm
0.000 0.444 0.556
M79.63 Pain in limb (Forearm)
0.000 0.444 0.556
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.444 0.555
M07.38 Other psoriatic arthropathies (Other)
0.000 0.445 0.554
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.445 0.554
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.445 0.554
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.445 0.554
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.445 0.554
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.445 0.554
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.445 0.554
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.445 0.554
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.447 0.553
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.448 0.552
M06.38 Rheumatoid nodule (Other)
0.000 0.448 0.552
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.448 0.552
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.448 0.552
M06.33 Rheumatoid nodule (Forearm)
0.000 0.448 0.552
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.448 0.552
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.448 0.552
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.448 0.552
M46 Other inflammatory spondylopathies
0.000 0.449 0.551
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.547 0.449 0.004
M91-M94 Chondropathies
0.000 0.453 0.547
I44.0 Atrioventricular block, first degree
0.000 0.454 0.546
M79.78 Fibromyalgia (Other)
0.000 0.455 0.545
M79.77 Fibromyalgia (Ankle and foot)
0.000 0.455 0.545
M79.76 Fibromyalgia (Lower leg)
0.000 0.455 0.545
M79.75 Fibromyalgia (Pelvic region and thigh)
0.000 0.455 0.545
M79.74 Fibromyalgia (Hand)
0.000 0.455 0.545
M79.73 Fibromyalgia (Forearm)
0.000 0.455 0.545
M79.72 Fibromyalgia (Upper arm)
0.000 0.455 0.545
M79.71 Fibromyalgia (Shoulder region)
0.000 0.455 0.545
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.456 0.544
E45 Retarded development following protein-energy malnutrition
0.000 0.456 0.544
E43 Unspecified severe protein-energy malnutrition
0.000 0.456 0.544
E42 Marasmic kwashiorkor
0.000 0.456 0.544
E41 Nutritional marasmus
0.000 0.456 0.544
E40 Kwashiorkor
0.000 0.456 0.544
M12 Other specific arthropathies
0.000 0.461 0.539
M79.4 Hypertrophy of (infrapatellar) fat pad
0.000 0.463 0.537
I44.7 Left bundle-branch block, unspecified
0.000 0.464 0.536
M79.69 Pain in limb (Site unspecified)
0.000 0.465 0.535
M79.68 Pain in limb (Other)
0.000 0.467 0.533
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.533 0.467 0.000
M79.15 Myalgia (Pelvic region and thigh)
0.000 0.468 0.532
E85.8 Other amyloidosis
0.000 0.468 0.532
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.468 0.532
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.468 0.532
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.468 0.532
E28.2 Polycystic ovarian syndrome
0.000 0.469 0.531
E07.8 Other specified disorders of thyroid
0.000 0.471 0.529
K90 Intestinal malabsorption
0.000 0.471 0.528
E29 Testicular dysfunction
0.000 0.472 0.528
I45 Other conduction disorders
0.000 0.473 0.527
H71 Cholesteatoma of middle ear
0.000 0.476 0.524
I83.1 Varicose veins of lower extremities with inflammation
0.521 0.476 0.002
M14 Arthropathies in other diseases classified elsewhere
0.000 0.478 0.522
M79.16 Myalgia (Lower leg)
0.000 0.480 0.520
I51.9 Heart disease, unspecified
0.000 0.481 0.519
E06 Thyroiditis
0.000 0.482 0.518
M77.12 Lateral epicondylitis (Upper arm)
0.000 0.483 0.517
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.484 0.516
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
I23.8 Other current complications following acute myocardial infarction
0.000 0.486 0.514
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.486 0.514
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.486 0.514
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.000 0.486 0.513
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.488 0.512
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.488 0.512
E70.3 Albinism
0.000 0.488 0.512
E70.2 Disorders of tyrosine metabolism
0.000 0.488 0.512
E70.1 Other hyperphenylalaninaemias
0.000 0.488 0.512
E70.0 Classical phenylketonuria
0.000 0.488 0.512
E71.3 Disorders of fatty-acid metabolism
0.000 0.488 0.512
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.488 0.512
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.488 0.512
E71.0 Maple-syrup-urine disease
0.000 0.488 0.512
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.488 0.512
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.488 0.512
E72.5 Disorders of glycine metabolism
0.000 0.488 0.512
E72.4 Disorders of ornithine metabolism
0.000 0.488 0.512
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.488 0.512
E72.2 Disorders of urea cycle metabolism
0.000 0.488 0.512
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.488 0.512
E72.0 Disorders of amino-acid transport
0.000 0.488 0.512
E75.6 Lipid storage disorder, unspecified
0.000 0.488 0.512
E75.5 Other lipid storage disorders
0.000 0.488 0.512
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.488 0.512
E75.3 Sphingolipidosis, unspecified
0.000 0.488 0.512
E75.2 Other sphingolipidosis
0.000 0.488 0.512
E75.1 Other gangliosidosis
0.000 0.488 0.512
E75.0 GM2 gangliosidosis
0.000 0.488 0.512
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.488 0.512
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.488 0.512
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.488 0.512
E76.2 Other mucopolysaccharidoses
0.000 0.488 0.512
E76.1 Mucopolysaccharidosis, type II
0.000 0.488 0.512
E76.0 Mucopolysaccharidosis, type I
0.000 0.488 0.512
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.488 0.512
E77.8 Other disorders of glycoprotein metabolism
0.000 0.488 0.512
E77.1 Defects in glycoprotein degradation
0.000 0.488 0.512
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.488 0.512
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.488 0.512
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.488 0.512
E79.1 Lesch-Nyhan syndrome
0.000 0.488 0.512
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.488 0.512
E16.2 Hypoglycaemia, unspecified
0.000 0.488 0.512
M79.19 Myalgia (Site unspecified)
0.000 0.491 0.509
M70.6 Trochanteric bursitis
0.000 0.492 0.508
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.493 0.507
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.493 0.507
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.493 0.507
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.493 0.507
E26 Hyperaldosteronism
0.000 0.493 0.507
M79.17 Myalgia (Ankle and foot)
0.000 0.493 0.507
M79.14 Myalgia (Hand)
0.000 0.493 0.507
M79.13 Myalgia (Forearm)
0.000 0.493 0.507
M79.12 Myalgia (Upper arm)
0.000 0.493 0.507
K51 Ulcerative colitis
0.507 0.493 0.000
E88 Other metabolic disorders
0.000 0.493 0.506
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.494 0.506
E32 Diseases of thymus
0.000 0.494 0.506
E31 Polyglandular dysfunction
0.000 0.494 0.506
E30 Disorders of puberty, not elsewhere classified
0.000 0.494 0.506
E25 Adrenogenital disorders
0.000 0.494 0.506
E61.1 Iron deficiency
0.000 0.495 0.505
I51.0 Cardiac septal defect, acquired
0.000 0.495 0.505
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.497 0.503
K51.9 Ulcerative colitis, unspecified
0.503 0.497 0.000
I44.3 Other and unspecified atrioventricular block
0.000 0.498 0.502
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.499 0.501
I02 Rheumatic chorea
0.000 0.501 0.499
I01 Rheumatic fever with heart involvement
0.000 0.501 0.499
I00 Rheumatic fever without mention of heart involvement
0.000 0.501 0.499
E22 Hyperfunction of pituitary gland
0.000 0.505 0.495
M79.61 Pain in limb (Shoulder region)
0.000 0.505 0.495
M79.11 Myalgia (Shoulder region)
0.000 0.506 0.494
H74 Other disorders of middle ear and mastoid
0.000 0.507 0.493
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.508 0.492
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.508 0.492
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.508 0.492
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.508 0.492
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.508 0.492
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.508 0.492
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.508 0.492
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.508 0.492
M70.46 Prepatellar bursitis-Lower Leg
0.000 0.508 0.492
I20.8 Other forms of angina pectoris
0.000 0.509 0.491
I45.1 Other and unspecified right bundle-branch block
0.000 0.509 0.491
H61 Other disorders of external ear
0.000 0.510 0.490
I05-I09 Chronic rheumatic heart diseases
0.000 0.510 0.489
H60.3 Other infective otitis externa
0.000 0.512 0.488
M49.5 Collapsed vertebra in diseases classified elsewhere
0.000 0.513 0.487
K51.3 Ulcerative (chronic) rectosigmoiditis
0.486 0.514 0.000
E84.8 Cystic fibrosis with other manifestations
0.000 0.514 0.485
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.514 0.485
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.514 0.485
E24.9 Cushing's syndrome, unspecified
0.000 0.515 0.485
E23.7 Disorder of pituitary gland, unspecified
0.000 0.517 0.483
M77.4 Metatarsalgia
0.000 0.518 0.482
L41.9 Parapsoriasis, unspecified
0.000 0.520 0.479
L41.8 Other parapsoriasis
0.000 0.520 0.479
L41.5 Retiform parapsoriasis
0.000 0.520 0.479
L41.4 Large plaque parapsoriasis
0.000 0.520 0.479
L41.3 Small plaque parapsoriasis
0.000 0.520 0.479
L41.2 Lymphomatoid papulosis
0.000 0.520 0.479
L41.1 Pityriasis lichenoides chronica
0.000 0.520 0.479
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.520 0.479
L44.9 Papulosquamous disorder, unspecified
0.000 0.520 0.479
L44.8 Other specified papulosquamous disorders
0.000 0.520 0.479
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.520 0.479
L44.3 Lichen ruber moniliformis
0.000 0.520 0.479
L44.2 Lichen striatus
0.000 0.520 0.479
L44.1 Lichen nitidus
0.000 0.520 0.479
L44.0 Pityriasis rubra pilaris
0.000 0.520 0.479
E23.2 Diabetes insipidus
0.000 0.521 0.479
H73 Other disorders of tympanic membrane
0.000 0.522 0.478
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.524 0.475
E63 Other nutritional deficiencies
0.000 0.524 0.475
E56 Other vitamin deficiencies
0.000 0.524 0.475
E51 Thiamine deficiency
0.000 0.524 0.475
E50 Vitamin A deficiency
0.000 0.524 0.475
E60 Dietary zinc deficiency
0.000 0.524 0.475
E59 Dietary selenium deficiency
0.000 0.524 0.475
E58 Dietary calcium deficiency
0.000 0.524 0.475
E54 Ascorbic acid deficiency
0.000 0.524 0.475
E52 Niacin deficiency [pellagra]
0.000 0.524 0.475
M79.2 Neuralgia and neuritis, unspecified
0.000 0.525 0.475
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.525 0.474
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.525 0.474

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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