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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3131090
log Bayes Factor = 54.6205
Chromosome 6   position 29,072,288  (GRCh37) Explore rs3131090 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.001 0.999
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.001 0.999
E16.2 Hypoglycaemia, unspecified
0.000 0.002 0.998
E16 Other disorders of pancreatic internal secretion
0.000 0.002 0.998
E10-E14 Diabetes mellitus
0.000 0.002 0.998
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.002 0.998
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.002 0.998
E00-E07 Disorders of thyroid gland
0.000 0.004 0.996
E10.3 With ophthalmic complications
0.000 0.009 0.991
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.034 0.966
E10.2 With renal complications
0.000 0.044 0.956
E10.4 With neurological complications
0.000 0.116 0.884
E10.1 With ketoacidosis
0.000 0.122 0.878
E05.8 Other thyrotoxicosis
0.000 0.196 0.804
E16.1 Other hypoglycaemia
0.000 0.205 0.795
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.215 0.785
E13 Other specified diabetes mellitus
0.000 0.227 0.772
E40-E46 Malnutrition
0.000 0.238 0.762
E10.7 With multiple complications
0.000 0.245 0.754
E05.5 Thyroid crisis or storm
0.000 0.284 0.716
E05.4 Thyrotoxicosis factitia
0.000 0.284 0.716
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.284 0.716
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.284 0.715
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.284 0.715
E16.4 Abnormal secretion of gastrin
0.000 0.284 0.715
E16.3 Increased secretion of glucagon
0.000 0.284 0.715
E12 Malnutrition-related diabetes mellitus
0.000 0.284 0.715
E15 Nondiabetic hypoglycaemic coma
0.000 0.285 0.715
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.286 0.714
E00 Congenital iodine-deficiency syndrome
0.000 0.286 0.714
E10.0 With coma
0.000 0.288 0.712
E14 Unspecified diabetes mellitus
0.000 0.324 0.676
E10.6 With other specified complications
0.000 0.342 0.657
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.358 0.642
E10.5 With peripheral circulatory complications
0.000 0.359 0.641
E07 Other disorders of thyroid
0.000 0.377 0.623
E13.9 Without complications
0.000 0.380 0.620
E06 Thyroiditis
0.000 0.392 0.608
E46 Unspecified protein-energy malnutrition
0.000 0.408 0.592
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.412 0.587
E14.3 With ophthalmic complications
0.000 0.424 0.576
E13.8 With unspecified complications
0.000 0.446 0.554
E13.7 With multiple complications
0.000 0.446 0.554
E13.6 With other specified complications
0.000 0.446 0.554
E13.5 With peripheral circulatory complications
0.000 0.446 0.554
E13.4 With neurological complications
0.000 0.446 0.554
E13.2 With renal complications
0.000 0.446 0.554
E13.1 With ketoacidosis
0.000 0.446 0.554
E13.0 With coma
0.000 0.446 0.554
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.454 0.546
E45 Retarded development following protein-energy malnutrition
0.000 0.454 0.546
E43 Unspecified severe protein-energy malnutrition
0.000 0.454 0.546
E42 Marasmic kwashiorkor
0.000 0.454 0.546
E41 Nutritional marasmus
0.000 0.454 0.546
E40 Kwashiorkor
0.000 0.454 0.546
E13.3 With ophthalmic complications
0.000 0.459 0.540
E14.1 With ketoacidosis
0.000 0.463 0.537
E03 Other hypothyroidism
0.000 0.469 0.531
E10.8 With unspecified complications
0.000 0.470 0.529
E14.8 With unspecified complications
0.000 0.483 0.517
E12.9 Without complications
0.000 0.487 0.513
E12.8 With unspecified complications
0.000 0.487 0.513
E12.7 With multiple complications
0.000 0.487 0.513
E12.6 With other specified complications
0.000 0.487 0.513
E12.5 With peripheral circulatory complications
0.000 0.487 0.513
E12.4 With neurological complications
0.000 0.487 0.513
E12.3 With ophthalmic complications
0.000 0.487 0.513
E12.2 With renal complications
0.000 0.487 0.513
E12.1 With ketoacidosis
0.000 0.487 0.513
E12.0 With coma
0.000 0.487 0.513
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.488 0.512
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.488 0.512
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.488 0.512
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.488 0.512
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.488 0.512
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.488 0.512
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.488 0.512
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.488 0.512
E14.4 With neurological complications
0.000 0.488 0.512
E06.9 Thyroiditis, unspecified
0.000 0.495 0.505
E14.6 With other specified complications
0.000 0.498 0.502
E07.8 Other specified disorders of thyroid
0.000 0.506 0.493
E14.7 With multiple complications
0.000 0.515 0.485
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.465 0.535 0.000
E14.5 With peripheral circulatory complications
0.000 0.535 0.464
E14.0 With coma
0.000 0.543 0.456
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.544 0.455
K90 Intestinal malabsorption
0.000 0.547 0.453
E14.2 Withrenal complications
0.000 0.551 0.448
E07.1 Dyshormogenetic goitre
0.000 0.553 0.447
E07.0 Hypersecretion of calcitonin
0.000 0.553 0.447
E06.1 Subacute thyroiditis
0.000 0.557 0.443
E06.4 Drug-induced thyroiditis
0.000 0.564 0.436
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.564 0.436
E06.0 Acute thyroiditis
0.000 0.564 0.436
E06.5 Other chronic thyroiditis
0.000 0.577 0.422
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.600 0.400
E44.1 Mild protein-energy malnutrition
0.000 0.608 0.391
E44.0 Moderate protein-energy malnutrition
0.000 0.608 0.391
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.608 0.391
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.618 0.382
E03.5 Myxoedema coma
0.000 0.619 0.381
E03.4 Atrophy of thyroid (acquired)
0.000 0.619 0.381
E03.3 Postinfectious hypothyroidism
0.000 0.619 0.381
E03.1 Congenital hypothyroidism without goitre
0.000 0.630 0.370
E65-E68 Obesity and other hyperalimentation
0.000 0.655 0.344
E50-E64 Other nutritional deficiencies
0.000 0.664 0.336
E03.8 Other specified hypothyroidism
0.000 0.670 0.330
K90.3 Pancreatic steatorrhoea
0.000 0.675 0.325
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.675 0.325
K90.1 Tropical sprue
0.000 0.675 0.325
K90.8 Other intestinal malabsorption
0.000 0.683 0.317
E07.9 Disorder of thyroid, unspecified
0.000 0.739 0.261
K90.9 Intestinal malabsorption, unspecified
0.000 0.747 0.253
E67 Other hyperalimentation
0.000 0.753 0.247
E68 Sequelae of hyperalimentation
0.000 0.753 0.247
E20-E35 Disorders of other endocrine glands
0.000 0.757 0.243
E51 Thiamine deficiency
0.000 0.758 0.242
E03.9 Hypothyroidism, unspecified
0.000 0.759 0.241
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.759 0.241
E50 Vitamin A deficiency
0.000 0.759 0.241
E60 Dietary zinc deficiency
0.000 0.759 0.241
E59 Dietary selenium deficiency
0.000 0.759 0.241
E52 Niacin deficiency [pellagra]
0.000 0.759 0.241
E54 Ascorbic acid deficiency
0.000 0.763 0.237
E56 Other vitamin deficiencies
0.000 0.771 0.229
E24 Cushing's syndrome
0.000 0.775 0.225
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.777 0.223
E58 Dietary calcium deficiency
0.000 0.777 0.222
E55 Vitamin D deficiency
0.000 0.780 0.220
E63 Other nutritional deficiencies
0.000 0.781 0.219
E21.3 Hyperparathyroidism, unspecified
0.000 0.787 0.213
E61 Deficiency of other nutrient elements
0.000 0.797 0.203
E65 Localised adiposity
0.000 0.799 0.201
E24.9 Cushing's syndrome, unspecified
0.000 0.805 0.195
M45.X9 Ankylosing spondylitis (Site unspecified)
0.190 0.810 0.000
E24.0 Pituitary-dependent Cushing's disease
0.000 0.811 0.189
E24.2 Drug-induced Cushing's syndrome
0.000 0.821 0.178
E67.8 Other specified hyperalimentation
0.000 0.822 0.177
E67.3 Hypervitaminosis D
0.000 0.822 0.177
E67.2 Megavitamin-B6 syndrome
0.000 0.822 0.177
E67.1 Hypercarotenaemia
0.000 0.822 0.177
E67.0 Hypervitaminosis A
0.000 0.822 0.177
E53 Deficiency of other B group vitamins
0.000 0.823 0.177
E20 Hypoparathyroidism
0.000 0.824 0.176
E21.4 Other specified disorders of parathyroid gland
0.000 0.825 0.174
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.826 0.174
E32 Diseases of thymus
0.000 0.826 0.174
E30 Disorders of puberty, not elsewhere classified
0.000 0.826 0.174
E51.2 Wernicke's encephalopathy
0.000 0.826 0.174
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.826 0.174
E51.9 Thiamine deficiency, unspecified
0.000 0.826 0.173
E51.8 Other manifestations of thiamine deficiency
0.000 0.826 0.173
E51.1 Beriberi
0.000 0.826 0.173
E50.9 Vitamin A deficiency, unspecified
0.000 0.827 0.173
E50.8 Other manifestations of vitamin A deficiency
0.000 0.827 0.173
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.827 0.173
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.827 0.173
E50.5 Vitamin A deficiency with night blindness
0.000 0.827 0.173
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.827 0.173
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.827 0.173
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.827 0.173
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.827 0.173
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.827 0.173
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.827 0.173
E64.8 Sequelae of other nutritional deficiencies
0.000 0.827 0.173
E64.3 Sequelae of rickets
0.000 0.827 0.173
E64.2 Sequelae of vitamin C deficiency
0.000 0.827 0.173
E64.1 Sequelae of vitamin A deficiency
0.000 0.827 0.173
E64.0 Sequelae of protein-energy malnutrition
0.000 0.827 0.173
E25 Adrenogenital disorders
0.000 0.830 0.170
C19 Malignant neoplasm of rectosigmoid junction
0.000 0.832 0.168
E31 Polyglandular dysfunction
0.000 0.833 0.167
E56.9 Vitamin deficiency, unspecified
0.000 0.835 0.164
E56.8 Deficiency of other vitamins
0.000 0.835 0.164
E56.0 Deficiency of vitamin E
0.000 0.835 0.164
E24.8 Other Cushing's syndrome
0.000 0.838 0.162
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.838 0.162
E24.3 Ectopic ACTH syndrome
0.000 0.838 0.162
E24.1 Nelson's syndrome
0.000 0.838 0.162
E21.2 Other hyperparathyroidism
0.000 0.838 0.162
E55.0 Rickets, active
0.000 0.842 0.158
E63.8 Other specified nutritional deficiencies
0.000 0.843 0.157
E63.1 Imbalance of constituents of food intake
0.000 0.843 0.157
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.843 0.157
E06.3 Autoimmune thyroiditis
0.001 0.845 0.154
E28 Ovarian dysfunction
0.000 0.846 0.154
E56.1 Deficiency of vitamin K
0.000 0.847 0.152
E11 Non-insulin-dependent diabetes mellitus
0.000 0.852 0.148
R31 Unspecified haematuria
0.147 0.853 0.000
E61.9 Deficiency of nutrient element, unspecified
0.000 0.854 0.146
E61.8 Deficiency of other specified nutrient elements
0.000 0.854 0.146
E61.7 Deficiency of multiple nutrient elements
0.000 0.854 0.146
E61.6 Vanadium deficiency
0.000 0.854 0.146
E61.5 Molybdenum deficiency
0.000 0.854 0.146
E61.4 Chromium deficiency
0.000 0.854 0.146
E61.3 Manganese deficiency
0.000 0.854 0.146
E61.0 Copper deficiency
0.000 0.854 0.146
E29 Testicular dysfunction
0.000 0.856 0.144
E53.9 Vitamin B deficiency, unspecified
0.000 0.862 0.138
E55.9 Vitamin D deficiency, unspecified
0.000 0.864 0.136
E34 Other endocrine disorders
0.000 0.865 0.135
E63.9 Nutritional deficiency, unspecified
0.000 0.865 0.134
E11.6 With other specified complications
0.000 0.866 0.134
E61.1 Iron deficiency
0.000 0.867 0.133
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.867 0.132
E83 Disorders of mineral metabolism
0.125 0.871 0.005
E20.9 Hypoparathyroidism, unspecified
0.000 0.871 0.129
E53.1 Pyridoxine deficiency
0.000 0.873 0.127
E53.0 Riboflavin deficiency
0.000 0.873 0.127
E20.8 Other hypoparathyroidism
0.000 0.873 0.127
E20.1 Pseudohypoparathyroidism
0.000 0.873 0.127
E20.0 Idiopathic hypoparathyroidism
0.000 0.873 0.127
E61.2 Magnesium deficiency
0.000 0.875 0.125
E30.9 Disorder of puberty, unspecified
0.000 0.875 0.125
E30.8 Other disorders of puberty
0.000 0.875 0.125
E30.1 Precocious puberty
0.000 0.875 0.125
E30.0 Delayed puberty
0.000 0.875 0.125
E32.9 Disease of thymus, unspecified
0.000 0.875 0.125
E32.8 Other diseases of thymus
0.000 0.875 0.125
E32.1 Abscess of thymus
0.000 0.875 0.125
E32.0 Persistent hyperplasia of thymus
0.000 0.875 0.125
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.875 0.125
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.875 0.125
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.875 0.125
E25.9 Adrenogenital disorder, unspecified
0.000 0.878 0.122
E25.8 Other adrenogenital disorders
0.000 0.878 0.122
E31.9 Polyglandular dysfunction, unspecified
0.000 0.880 0.120
E31.8 Other polyglandular dysfunction
0.000 0.880 0.120
E31.1 Polyglandular hyperfunction
0.000 0.880 0.120
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.882 0.117
E26 Hyperaldosteronism
0.000 0.884 0.115
E11.2 With renal complications
0.000 0.886 0.114
E11.0 With coma
0.000 0.886 0.114
E31.0 Autoimmune polyglandular failure
0.000 0.887 0.112
E21.0 Primary hyperparathyroidism
0.000 0.887 0.113
E28.9 Ovarian dysfunction, unspecified
0.000 0.889 0.111
E28.8 Other ovarian dysfunction
0.000 0.889 0.111
E28.1 Androgen excess
0.000 0.889 0.111
E28.0 Oestrogen excess
0.000 0.889 0.111
E28.2 Polycystic ovarian syndrome
0.000 0.892 0.108
C20 Malignant neoplasm of rectum
0.000 0.892 0.108
C15-C26 Malignant neoplasms of digestive organs
0.000 0.892 0.108
E11.1 With ketoacidosis
0.000 0.893 0.107
E11.7 With multiple complications
0.000 0.894 0.106
E29.9 Testicular dysfunction, unspecified
0.000 0.897 0.103
E29.8 Other testicular dysfunction
0.000 0.897 0.103
E29.0 Testicular hyperfunction
0.000 0.897 0.103
E83.3 Disorders of phosphorus metabolism
0.102 0.897 0.001
C15 Malignant neoplasm of oesophagus
0.000 0.898 0.102
E34.3 Short stature, not elsewhere classified
0.000 0.901 0.099
E34.5 Androgen resistance syndrome
0.000 0.903 0.097
E34.4 Constitutional tall stature
0.000 0.903 0.097
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.903 0.097
E34.1 Other hypersecretion of intestinal hormones
0.000 0.903 0.097
E28.3 Primary ovarian failure
0.000 0.905 0.095
E22 Hyperfunction of pituitary gland
0.000 0.905 0.095
C25 Malignant neoplasm of pancreas
0.000 0.906 0.094
E83.8 Other disorders of mineral metabolism
0.089 0.907 0.004
E83.2 Disorders of zinc metabolism
0.089 0.907 0.004
E83.0 Disorders of copper metabolism
0.089 0.907 0.004
S02.40 Fracture of malar and maxillary bones (closed)
0.000 0.908 0.092
E83.9 Disorder of mineral metabolism, unspecified
0.089 0.908 0.004
M45 Ankylosing spondylitis
0.091 0.909 0.000
C15.5 Lower third of oesophagus
0.000 0.909 0.091
E34.9 Endocrine disorder, unspecified
0.000 0.911 0.089
E11.8 With unspecified complications
0.000 0.912 0.088
C15.4 Middle third of oesophagus
0.000 0.913 0.087
E34.8 Other specified endocrine disorders
0.000 0.915 0.085
E34.0 Carcinoid syndrome
0.000 0.917 0.083
E26.8 Other hyperaldosteronism
0.000 0.917 0.083
E26.1 Secondary hyperaldosteronism
0.000 0.917 0.083
C15.9 Oesophagus, unspecified
0.000 0.917 0.083
I83 Varicose veins of lower extremities
0.081 0.919 0.000
C17 Malignant neoplasm of small intestine
0.000 0.919 0.081
S02.4 Fracture of malar and maxillary bones
0.000 0.919 0.081
C25.1 Body of pancreas
0.000 0.919 0.080
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.000 0.920 0.080
C25.3 Pancreatic duct
0.000 0.921 0.079
C25.2 Tail of pancreas
0.000 0.922 0.078
C15.0 Cervical part of oesophagus
0.000 0.923 0.077
C17.0 Duodenum
0.000 0.924 0.076
E26.9 Hyperaldosteronism, unspecified
0.001 0.926 0.073
C25.4 Endocrine pancreas
0.000 0.926 0.074
S02 Fracture of skull and facial bones
0.000 0.926 0.074
C15.8 Overlapping lesion of oesophagus
0.000 0.927 0.073
C15.2 Abdominal part of oesophagus
0.000 0.927 0.073
E29.1 Testicular hypofunction
0.000 0.927 0.072
M45.X2 Ankylosing spondylitis (Cervical region)
0.073 0.927 0.000
C24.0 Extrahepatic bile duct
0.000 0.928 0.072
C15.1 Thoracic part of oesophagus
0.000 0.928 0.072
C25.8 Overlapping lesion of pancreas
0.000 0.928 0.072
M45.X6 Ankylosing spondylitis (Lumbar region)
0.069 0.930 0.000
E22.8 Other hyperfunction of pituitary gland
0.000 0.932 0.068
E14.9 Without complications
0.000 0.933 0.067
C25.9 Pancreas, unspecified
0.000 0.933 0.067
S02.0 Fracture of vault of skull
0.000 0.935 0.065
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.065 0.935 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.065 0.935 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.065 0.935 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.065 0.935 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.065 0.935 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.065 0.935 0.000
E23 Hypofunction and other disorders of pituitary gland
0.000 0.935 0.065
E22.1 Hyperprolactinaemia
0.000 0.935 0.065
S02.8 Fractures of other skull and facial bones
0.000 0.935 0.065
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.936 0.064
C15.3 Upper third of oesophagus
0.000 0.936 0.064
C21 Malignant neoplasm of anus and anal canal
0.000 0.937 0.063
C25.7 Other parts of pancreas
0.000 0.937 0.062
S02.3 Fracture of orbital floor
0.000 0.940 0.060
S02.00 Fracture of vault of skull (closed)
0.000 0.940 0.060
C17.8 Overlapping lesion of small intestine
0.000 0.942 0.058
C17.3 Meckel's diverticulum
0.000 0.942 0.058
S02.6 Fracture of mandible
0.000 0.942 0.058
S02.80 Fractures of other skull and facial bones (closed)
0.000 0.942 0.058
C24.8 Overlapping lesion of biliary tract
0.000 0.942 0.058
S02.7 Multiple fractures involving skull and facial bones
0.000 0.943 0.057
S02.5 Fracture of tooth
0.000 0.943 0.057
E11.3 With ophthalmic complications
0.000 0.943 0.057
I83.0 Varicose veins of lower extremities with ulcer
0.056 0.944 0.000
C24.9 Biliary tract, unspecified
0.000 0.944 0.056
C17.1 Jejunum
0.000 0.945 0.055
S02.41 Fracture of malar and maxillary bones (open)
0.000 0.946 0.054
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.053 0.947 0.000
E23.7 Disorder of pituitary gland, unspecified
0.000 0.948 0.051
C26 Malignant neoplasm of other and ill-defined digestive organs
0.000 0.949 0.051
S02.30 Fracture of orbital floor (closed)
0.000 0.949 0.051
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.051 0.949 0.000
C23 Malignant neoplasm of gallbladder
0.000 0.949 0.050
S02.9 Fracture of skull and facial bones, part unspecified
0.000 0.949 0.050
S02.2 Fracture of nasal bones
0.000 0.950 0.050
C21.8 Overlapping lesion of rectum, anus and anal canal
0.000 0.950 0.049
E11.5 With peripheral circulatory complications
0.000 0.951 0.049
E22.0 Acromegaly and pituitary gigantism
0.000 0.952 0.048
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.952 0.047
S02.60 Fracture of mandible (closed)
0.000 0.953 0.047
S02.01 Fracture of vault of skull (open)
0.000 0.953 0.047
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.953 0.047
E23.1 Drug-induced hypopituitarism
0.000 0.953 0.047
S02.81 Fractures of other skull and facial bones (open)
0.000 0.953 0.046
S02.70 Multiple fractures involving skull and facial bones (closed)
0.000 0.954 0.046
E04 Other non-toxic goitre
0.003 0.955 0.043
C21.2 Cloacogenic zone
0.000 0.955 0.045
E26.0 Primary hyperaldosteronism
0.001 0.955 0.044
S02.50 Fracture of tooth (closed)
0.000 0.955 0.045
E83.4 Disorders of magnesium metabolism
0.042 0.956 0.002
E27 Other disorders of adrenal gland
0.000 0.956 0.044
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.000 0.956 0.044
Z71.8 Other specified counselling
0.044 0.956 0.000
S02.31 Fracture of orbital floor (open)
0.000 0.956 0.043
C17.9 Small intestine, unspecified
0.000 0.957 0.043
S02.1 Fracture of base of skull
0.000 0.957 0.043
S02.61 Fracture of mandible (open)
0.000 0.958 0.042
S02.71 Multiple fractures involving skull and facial bones (open)
0.000 0.959 0.041
C18 Malignant neoplasm of colon
0.000 0.959 0.041
S02.51 Fracture of tooth (open)
0.000 0.959 0.041
C18.9 Colon, unspecified
0.000 0.959 0.041
S02.21 Fracture of nasal bones (open)
0.000 0.959 0.041
C18.1 Appendix
0.000 0.961 0.039
C17.2 Ileum
0.000 0.962 0.038
C21.0 Anus, unspecified
0.000 0.963 0.037
C26.8 Overlapping lesion of digestive system
0.000 0.963 0.037
C26.1 Spleen
0.000 0.963 0.037
S02.91 Fracture of skull and facial bones, part unspecified (open)
0.000 0.963 0.036
C21.1 Anal canal
0.000 0.966 0.034
S02.90 Fracture of skull and facial bones, part unspecified (closed)
0.000 0.966 0.034
C25.0 Head of pancreas
0.000 0.967 0.033
E04.8 Other specified non-toxic goitre
0.002 0.967 0.031
E53.8 Deficiency of other specified B group vitamins
0.000 0.967 0.033
C24.1 Ampulla of Vater
0.001 0.968 0.031
E27.1 Primary adrenocortical insufficiency
0.000 0.968 0.032
E27.5 Adrenomedullary hyperfunction
0.000 0.968 0.031
E27.0 Other adrenocortical overactivity
0.000 0.968 0.031
C22.7 Other specified carcinomas of liver
0.000 0.968 0.031
C22.4 Other sarcomas of liver
0.000 0.968 0.031
C22.3 Angiosarcoma of liver
0.000 0.968 0.031
C22.2 Hepatoblastoma
0.000 0.968 0.031
C22.9 Liver, unspecified
0.000 0.968 0.031
C18.8 Overlapping lesion of colon
0.000 0.969 0.031
E23.6 Other disorders of pituitary gland
0.001 0.969 0.031
E11.4 With neurological complications
0.000 0.969 0.030
S02.11 Fracture of base of skull (open)
0.000 0.970 0.030
C18.4 Transverse colon
0.000 0.971 0.029
E23.2 Diabetes insipidus
0.000 0.972 0.028
E27.9 Disorder of adrenal gland, unspecified
0.000 0.972 0.028
K90-K93 Other diseases of the digestive system
0.000 0.972 0.028
E70-E90 Metabolic disorders
0.002 0.973 0.025
C26.9 Ill-defined sites within the digestive system
0.000 0.973 0.027
E27.2 Addisonian crisis
0.000 0.973 0.027
C26.0 Intestinal tract, part unspecified
0.000 0.973 0.027
C22.1 Intrahepatic bile duct carcinoma
0.000 0.973 0.026
S02.20 Fracture of nasal bones (closed)
0.000 0.974 0.026
E66 Obesity
0.000 0.974 0.026
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.976 0.024
E78.2 Mixed hyperlipidaemia
0.000 0.977 0.023
I77 Other disorders of arteries and arterioles
0.000 0.977 0.023
S00-S09 Injuries to the head
0.000 0.977 0.023
E04.0 Non-toxic diffuse goitre
0.003 0.977 0.020
C18.6 Descending colon
0.000 0.978 0.022
C16 Malignant neoplasm of stomach
0.000 0.978 0.022
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.978 0.022
I77.6 Arteritis, unspecified
0.000 0.978 0.022
S02.10 Fracture of base of skull (closed)
0.000 0.978 0.022
S05 Injury of eye and orbit
0.000 0.978 0.022
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.978 0.022
E78.5 Hyperlipidaemia, unspecified
0.000 0.978 0.022
I83.1 Varicose veins of lower extremities with inflammation
0.021 0.979 0.000
E73 Lactose intolerance
0.001 0.979 0.020
E27.8 Other specified disorders of adrenal gland
0.000 0.979 0.021
I77.1 Stricture of artery
0.000 0.979 0.021
H40.2 Primary angle-closure glaucoma
0.021 0.979 0.000
I77.8 Other specified disorders of arteries and arterioles
0.000 0.980 0.020
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.980 0.020
E78.1 Pure hyperglyceridaemia
0.000 0.980 0.020
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.001 0.980 0.019
E23.0 Hypopituitarism
0.000 0.980 0.019
E74 Other disorders of carbohydrate metabolism
0.001 0.980 0.019
E77 Disorders of glycoprotein metabolism
0.001 0.980 0.018
E76 Disorders of glycosaminoglycan metabolism
0.001 0.980 0.018
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.001 0.980 0.018
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.001 0.980 0.018
C18.7 Sigmoid colon
0.000 0.980 0.020
E11.9 Without complications
0.000 0.980 0.020
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body
0.000 0.981 0.019
C18.3 Hepatic flexure
0.000 0.981 0.019
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.981 0.019
E85 Amyloidosis
0.001 0.981 0.018
E78.6 Lipoprotein deficiency
0.000 0.981 0.019
E70 Disorders of aromatic amino-acid metabolism
0.001 0.981 0.018
E66.1 Drug-induced obesity
0.000 0.981 0.019
S05.6 Penetrating wound of eyeball without foreign body
0.000 0.981 0.019
S05.8 Other injuries of eye and orbit
0.000 0.982 0.018
S00 Superficial injury of head
0.000 0.982 0.018
E72 Other disorders of amino-acid metabolism
0.001 0.982 0.017
E78.3 Hyperchylomicronaemia
0.000 0.982 0.018
E79 Disorders of purine and pyrimidine metabolism
0.001 0.982 0.017
S05.3 Ocular laceration without prolapse or loss of intraocular tissue
0.000 0.982 0.018
S00.2 Other superficial injuries of eyelid and periocular area
0.000 0.982 0.018
E84 Cystic fibrosis
0.001 0.982 0.016
E88 Other metabolic disorders
0.001 0.982 0.017
I77.2 Rupture of artery
0.000 0.983 0.017
I77.3 Arterial fibromuscular dysplasia
0.000 0.983 0.017
S00.0 Superficial injury of scalp
0.000 0.983 0.017
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.983 0.017
E73.9 Lactose intolerance, unspecified
0.000 0.983 0.016
I77.5 Necrosis of artery
0.000 0.983 0.017
I77.4 Coeliac artery compression syndrome
0.000 0.983 0.017
S07 Crushing injury of head
0.000 0.983 0.017
S04 Injury of cranial nerves
0.000 0.983 0.017
I74 Arterial embolism and thrombosis
0.000 0.983 0.017
S08 Traumatic amputation of part of head
0.000 0.983 0.016
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.984 0.016
I73 Other peripheral vascular diseases
0.000 0.984 0.016
S05.5 Penetrating wound of eyeball with foreign body
0.000 0.984 0.016
S05.7 Avulsion of eye
0.000 0.984 0.016
S05.4 Penetrating wound of orbit with or without foreign body
0.000 0.984 0.016
S03 Dislocation, sprain and strain of joints and ligaments of head
0.000 0.984 0.016
S05.1 Contusion of eyeball and orbital tissues
0.000 0.984 0.016
C16.5 Lesser curvature of stomach, unspecified
0.000 0.984 0.016
E78.4 Other hyperlipidaemia
0.000 0.984 0.016
S00.4 Superficial injury of ear
0.000 0.985 0.015
I74.5 Embolism and thrombosis of iliac artery
0.000 0.985 0.015
E73.8 Other lactose intolerance
0.001 0.985 0.015
E73.1 Secondary lactase deficiency
0.001 0.985 0.015
E73.0 Congenital lactase deficiency
0.001 0.985 0.015
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.985 0.015
I73.9 Peripheral vascular disease, unspecified
0.000 0.985 0.015
E85.4 Organ-limited amyloidosis
0.001 0.985 0.015
E66.0 Obesity due to excess calories
0.000 0.985 0.015
C16.2 Body of stomach
0.000 0.985 0.015
E75.5 Other lipid storage disorders
0.001 0.985 0.014
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.985 0.015
K93.1 Megacolon in Chagas' disease
0.000 0.985 0.015
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.985 0.015
E74.3 Other disorders of intestinal carbohydrate absorption
0.001 0.985 0.014
C16.6 Greater curvature of stomach, unspecified
0.000 0.985 0.015
E88.9 Metabolic disorder, unspecified
0.000 0.985 0.014
E75.6 Lipid storage disorder, unspecified
0.001 0.985 0.014
E75.4 Neuronal ceroid lipofuscinosis
0.001 0.985 0.014
E75.3 Sphingolipidosis, unspecified
0.001 0.985 0.014
E75.1 Other gangliosidosis
0.001 0.985 0.014
E75.0 GM2 gangliosidosis
0.001 0.985 0.014
S09 Other and unspecified injuries of head
0.000 0.985 0.015
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue
0.000 0.985 0.014
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.985 0.014
C16.8 Overlapping lesion of stomach
0.000 0.986 0.014
E74.9 Disorder of carbohydrate metabolism, unspecified
0.001 0.986 0.014
E74.8 Other specified disorders of carbohydrate metabolism
0.001 0.986 0.014
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.001 0.986 0.014
E74.2 Disorders of galactose metabolism
0.001 0.986 0.014
E74.1 Disorders of fructose metabolism
0.001 0.986 0.014
E71.3 Disorders of fatty-acid metabolism
0.001 0.986 0.013
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.001 0.986 0.013
E71.1 Other disorders of branched-chain amino-acid metabolism
0.001 0.986 0.013
E71.0 Maple-syrup-urine disease
0.001 0.986 0.013

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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