TreeWAS – Variant ID: rs3131934

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	1.000	0.000	0.000
E05.9 Thyrotoxicosis, unspecified	1.000	0.000	0.000
E05.0 Thyrotoxicosis with diffuse goitre	1.000	0.000	0.000
E10.9 Without complications	1.000	0.000	0.000
M35.0 Sicca syndrome [Sjogren]	1.000	0.000	0.000
E05 Thyrotoxicosis [hyperthyroidism]	1.000	0.000	0.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000	0.000
R31 Unspecified haematuria	0.000	0.000	1.000
E10-E14 Diabetes mellitus	1.000	0.000	0.000
E00-E07 Disorders of thyroid gland	1.000	0.000	0.000
M20-M25 Other joint disorders	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
E10.3 With ophthalmic complications	1.000	0.000	0.000
Chapter VII Diseases of the eye and adnexa	1.000	0.000	0.000
H36.0 Diabetic retinopathy	1.000	0.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000	0.000
E03 Other hypothyroidism	1.000	0.000	0.000
M35 Other systemic involvement of connective tissue	1.000	0.000	0.000
E11 Non-insulin-dependent diabetes mellitus	1.000	0.000	0.000
H30-H36 Disorders of choroid and retina	1.000	0.000	0.000
H36 Retinal disorders in diseases classified elsewhere	1.000	0.000	0.000
E16 Other disorders of pancreatic internal secretion	1.000	0.000	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	1.000	0.000	0.000
E16.2 Hypoglycaemia, unspecified	1.000	0.000	0.000
D80-D89 Certain disorders involving the immune mechanism	1.000	0.000	0.000
E14 Unspecified diabetes mellitus	1.000	0.000	0.000
D60-D64 Aplastic and other anaemias	1.000	0.000	0.000
Chapter I Certain infectious and parasitic diseases	0.999	0.001	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.999	0.001	0.000
E20-E35 Disorders of other endocrine glands	0.999	0.001	0.000
Chapter IX Diseases of the circulatory system	0.999	0.001	0.000
E27 Other disorders of adrenal gland	0.999	0.001	0.000
E27.1 Primary adrenocortical insufficiency	0.998	0.002	0.000
D86 Sarcoidosis	0.998	0.002	0.000
D64 Other anaemias	0.998	0.002	0.000
D64.9 Anaemia, unspecified	0.997	0.003	0.000
E14.3 With ophthalmic complications	0.995	0.005	0.000
D86.9 Sarcoidosis, unspecified	0.995	0.005	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.994	0.006	0.000
E10.1 With ketoacidosis	0.994	0.006	0.000
E11.3 With ophthalmic complications	0.993	0.007	0.000
K70-K77 Diseases of liver	0.993	0.007	0.000
I73 Other peripheral vascular diseases	0.993	0.007	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.990	0.010	0.000
Chapter XX External causes of morbidity and mortality	0.989	0.011	0.000
E89.0 Postprocedural hypothyroidism	0.989	0.011	0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.988	0.012	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.985	0.015	0.000
K75 Other inflammatory liver diseases	0.985	0.015	0.000
E11.9 Without complications	0.984	0.016	0.000
E10.2 With renal complications	0.983	0.017	0.000
Chapter II Neoplasms	0.982	0.018	0.000
B35-B49 Mycoses	0.982	0.018	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.982	0.018	0.000
M60-M63 Disorders of muscles	0.980	0.020	0.000
K75.4 Autoimmune hepatitis	0.979	0.021	0.000
M24 Other specific joint derangements	0.979	0.021	0.000
D61 Other aplastic anaemias	0.979	0.021	0.000
E70-E90 Metabolic disorders	0.978	0.022	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.974	0.026	0.000
K72 Hepatic failure, not elsewhere classified	0.973	0.027	0.000
H34 Retinal vascular occlusions	0.970	0.030	0.000
B37 Candidiasis	0.970	0.030	0.000
E10.4 With neurological complications	0.970	0.030	0.000
I73.0 Raynaud's syndrome	0.969	0.031	0.000
E06 Thyroiditis	0.968	0.032	0.000
C15-C26 Malignant neoplasms of digestive organs	0.966	0.034	0.000
A30-A49 Other bacterial diseases	0.963	0.037	0.000
S00-S09 Injuries to the head	0.963	0.037	0.000
E50-E64 Other nutritional deficiencies	0.962	0.038	0.000
I74 Arterial embolism and thrombosis	0.960	0.040	0.000
M62 Other disorders of muscle	0.960	0.040	0.000
B15-B19 Viral hepatitis	0.959	0.041	0.000
C83.3 Large cell (diffuse)	0.958	0.042	0.000
K73 Chronic hepatitis, not elsewhere classified	0.956	0.044	0.000
E11.5 With peripheral circulatory complications	0.955	0.045	0.000
S01 Open wound of head	0.954	0.046	0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.953	0.047	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.951	0.049	0.000
Chapter XI Diseases of the digestive system	0.919	0.050	0.030
D61.9 Aplastic anaemia, unspecified	0.949	0.051	0.000
I77 Other disorders of arteries and arterioles	0.949	0.051	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.948	0.052	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.948	0.052	0.000
H05 Disorders of orbit	0.948	0.052	0.000
A41 Other septicaemia	0.945	0.055	0.000
J33 Nasal polyp	0.945	0.055	0.000
J33.0 Polyp of nasal cavity	0.944	0.056	0.000
E14.9 Without complications	0.943	0.057	0.000
I73.9 Peripheral vascular disease, unspecified	0.943	0.057	0.000
H34.8 Other retinal vascular occlusions	0.941	0.059	0.000
M62.8 Other specified disorders of muscle	0.939	0.061	0.000
A41.5 Septicaemia due to other Gram-negative organisms	0.936	0.064	0.000
H43-H45 Disorders of vitreous body and globe	0.935	0.065	0.000
B37.8 Candidiasis of other sites	0.934	0.066	0.000
B37.9 Candidiasis, unspecified	0.933	0.067	0.000
C16 Malignant neoplasm of stomach	0.932	0.068	0.000
Chapter X Diseases of the respiratory system	0.931	0.069	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.930	0.070	0.000
J33.9 Nasal polyp, unspecified	0.929	0.071	0.000
H06.2 Dysthyroid exophthalmos	0.927	0.073	0.000
J30-J39 Other diseases of upper respiratory tract	0.925	0.075	0.000
R30-R39 Symptoms and signs involving the urinary system	0.000	0.076	0.924
W00-W19 Falls	0.923	0.077	0.000
M22 Disorders of patella	0.922	0.078	0.000
E06.3 Autoimmune thyroiditis	0.922	0.078	0.000
M25 Other joint disorders, not elsewhere classified	0.919	0.081	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.917	0.083	0.000
K72.9 Hepatic failure, unspecified	0.917	0.083	0.000
D86.0 Sarcoidosis of lung	0.914	0.086	0.000
B18 Chronic viral hepatitis	0.914	0.086	0.000
K74 Fibrosis and cirrhosis of liver	0.913	0.087	0.000
D80 Immunodeficiency with predominantly antibody defects	0.912	0.088	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.911	0.089	0.000
S01.0 Open wound of scalp	0.911	0.089	0.000
S01.5 Open wound of lip and oral cavity	0.911	0.089	0.000
S06 Intracranial injury	0.910	0.090	0.000
S01.8 Open wound of other parts of head	0.910	0.090	0.000
H43 Disorders of vitreous body	0.909	0.091	0.000
I71 Aortic aneurysm and dissection	0.908	0.092	0.000
C92 Myeloid leukaemia	0.908	0.092	0.000
M05-M14 Inflammatory polyarthropathies	0.907	0.093	0.000
S40-S49 Injuries to the shoulder and upper arm	0.906	0.094	0.000
M24.2 Disorder of ligament	0.902	0.098	0.000
R39 Other symptoms and signs involving the urinary system	0.000	0.098	0.902
I77.1 Stricture of artery	0.901	0.099	0.000
S09 Other and unspecified injuries of head	0.901	0.099	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.900	0.100	0.000
R39.8 Other and unspecified symptoms and signs involving the urinary system	0.000	0.101	0.899
B25-B34 Other viral diseases	0.896	0.104	0.000
M15-M19 Arthrosis	0.896	0.104	0.000
I77.6 Arteritis, unspecified	0.894	0.106	0.000
K72.0 Acute and subacute hepatic failure	0.892	0.108	0.000
M34 Systemic sclerosis	0.891	0.109	0.000
R30 Pain associated with micturition	0.000	0.112	0.887
T20-T25 Burns and corrosions of external body surface, specified by site	0.886	0.114	0.000
W19 Unspecified fall	0.885	0.115	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.885	0.115	0.000
M62.86 Other specified disorders of muscle (Lower leg)	0.884	0.116	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.884	0.116	0.000
C81 Hodgkin's disease	0.884	0.116	0.000
A41.9 Septicaemia, unspecified	0.884	0.116	0.000
K90-K93 Other diseases of the digestive system	0.855	0.118	0.027
H43.1 Vitreous haemorrhage	0.882	0.118	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.880	0.120	0.000
H05.2 Exophthalmic conditions	0.880	0.120	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.880	0.120	0.000
J80-J84 Other respiratory diseases principally affecting the interstitium	0.880	0.120	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.879	0.121	0.000
Y52 Agents primarily affecting the cardiovascular system	0.878	0.122	0.000
E53 Deficiency of other B group vitamins	0.877	0.123	0.000
C88 Malignant immunoproliferative diseases	0.873	0.127	0.000
M17 Gonarthrosis [arthrosis of knee]	0.871	0.129	0.000
X20-X29 Contact with venomous animals and plants	0.871	0.129	0.000
C85.1 B-cell lymphoma, unspecified	0.869	0.131	0.000
M25.7 Osteophyte	0.869	0.131	0.000
B18.2 Chronic viral hepatitis C	0.869	0.131	0.000
K75.8 Other specified inflammatory liver diseases	0.869	0.131	0.000
E14.8 With unspecified complications	0.868	0.132	0.000
Chapter VI Diseases of the nervous system	0.868	0.132	0.000
J84 Other interstitial pulmonary diseases	0.868	0.132	0.000
R30.0 Dysuria	0.000	0.132	0.868
K74.6 Other and unspecified cirrhosis of liver	0.867	0.133	0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.867	0.133	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.862	0.138	0.000
B37.0 Candidal stomatitis	0.861	0.139	0.000
J84.9 Interstitial pulmonary disease, unspecified	0.861	0.139	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.859	0.141	0.000
C19 Malignant neoplasm of rectosigmoid junction	0.859	0.141	0.000
M32 Systemic lupus erythematosus	0.858	0.142	0.000
K90 Intestinal malabsorption	0.852	0.142	0.006
K73.9 Chronic hepatitis, unspecified	0.856	0.144	0.000
E11.6 With other specified complications	0.856	0.144	0.000
S06.3 Focal brain injury	0.856	0.144	0.000
K76 Other diseases of liver	0.855	0.145	0.000
I10-I15 Hypertensive diseases	0.854	0.146	0.000
V01-V09 Pedestrian injured in transport accident	0.853	0.147	0.000
V20-V29 Motorcycle rider injured in transport accident	0.853	0.147	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.852	0.148	0.000
S05 Injury of eye and orbit	0.852	0.148	0.000
B25 Cytomegaloviral disease	0.852	0.148	0.000
D83 Common variable immunodeficiency	0.851	0.149	0.000
C91 Lymphoid leukaemia	0.850	0.150	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.850	0.150	0.000
S06.5 Traumatic subdural haemorrhage	0.848	0.152	0.000
J37 Chronic laryngitis and laryngotracheitis	0.847	0.153	0.000
G50-G59 Nerve, nerve root and plexus disorders	0.847	0.153	0.000
C92.0 Acute myeloid leukaemia	0.847	0.153	0.000
S20-S29 Injuries to the thorax	0.846	0.154	0.000
C16.9 Stomach, unspecified	0.846	0.154	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.846	0.154	0.000
S09.9 Unspecified injury of head	0.845	0.155	0.000
W19.2 School, other institution and public administrative area	0.841	0.159	0.000
Y42.7 Androgens and anabolic congeners	0.839	0.161	0.000
M25.76 Osteophyte (Lower leg)	0.837	0.163	0.000
E11.1 With ketoacidosis	0.837	0.163	0.000
E10.5 With peripheral circulatory complications	0.836	0.163	0.000
C18 Malignant neoplasm of colon	0.836	0.164	0.000
R35 Polyuria	0.000	0.166	0.834
M00-M03 Infectious arthropathies	0.833	0.167	0.000
E06.9 Thyroiditis, unspecified	0.833	0.167	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.833	0.167	0.000
K90.9 Intestinal malabsorption, unspecified	0.831	0.168	0.001
X58-X59 Accidental exposure to other and unspecified factors	0.831	0.169	0.000
K70 Alcoholic liver disease	0.831	0.169	0.000
H03 Disorders of eyelid in diseases classified elsewhere	0.830	0.170	0.000
C20 Malignant neoplasm of rectum	0.827	0.173	0.000
W20-W49 Exposure to inanimate mechanical forces	0.827	0.173	0.000
E53.8 Deficiency of other specified B group vitamins	0.826	0.174	0.000
D50-D53 Nutritional anaemias	0.825	0.175	0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.825	0.175	0.000
S46 Injury of muscle and tendon at shoulder and upper arm level	0.824	0.176	0.000
E14.1 With ketoacidosis	0.823	0.177	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.821	0.179	0.000
E14.2 Withrenal complications	0.820	0.180	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.819	0.181	0.000
S06.30 Focal brain injury (without open intracranial wound)	0.818	0.182	0.000
E24 Cushing's syndrome	0.817	0.183	0.000
D55-D59 Haemolytic anaemias	0.815	0.185	0.000
G30-G32 Other degenerative diseases of the nervous system	0.814	0.186	0.000
I27 Other pulmonary heart diseases	0.814	0.186	0.000
M06 Other rheumatoid arthritis	0.813	0.187	0.000
M22.2 Patellofemoral disorders	0.813	0.187	0.000
M62.85 Other specified disorders of muscle (Pelvic region and thigh)	0.812	0.188	0.000
C16.8 Overlapping lesion of stomach	0.812	0.188	0.000
S02 Fracture of skull and facial bones	0.812	0.188	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.810	0.188	0.002
G51 Facial nerve disorders	0.812	0.188	0.000
M17.0 Primary gonarthrosis, bilateral	0.811	0.189	0.000
E11.7 With multiple complications	0.811	0.189	0.000
B25.9 Cytomegaloviral disease, unspecified	0.810	0.190	0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified	0.810	0.190	0.000
H34.2 Other retinal artery occlusions	0.810	0.190	0.000
E73 Lactose intolerance	0.809	0.191	0.000
M24.5 Contracture of joint	0.809	0.191	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.808	0.192	0.000
E51 Thiamine deficiency	0.808	0.192	0.000
M24.27 Disorder of ligament (Ankle and foot)	0.807	0.193	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.807	0.193	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.806	0.194	0.000
H05.8 Other disorders of orbit	0.805	0.194	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.804	0.196	0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.804	0.196	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.803	0.197	0.000
C04 Malignant neoplasm of floor of mouth	0.802	0.198	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.802	0.198	0.000
E07 Other disorders of thyroid	0.802	0.198	0.000
S20 Superficial injury of thorax	0.802	0.198	0.000
M35.7 Hypermobility syndrome	0.801	0.199	0.000
M24.26 Disorder of ligament (Lower leg)	0.801	0.199	0.000
C23 Malignant neoplasm of gallbladder	0.800	0.200	0.000
S49 Other and unspecified injuries of shoulder and upper arm	0.799	0.201	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.798	0.202	0.000
B17 Other acute viral hepatitis	0.798	0.202	0.000
M10 Gout	0.797	0.203	0.000
I12 Hypertensive renal disease	0.797	0.203	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.796	0.204	0.000
H30 Chorioretinal inflammation	0.796	0.204	0.000
E10.8 With unspecified complications	0.795	0.205	0.000
B20-B24 Human immunodeficiency virus [HIV] disease	0.795	0.205	0.000
K76.6 Portal hypertension	0.793	0.207	0.000
I74.8 Embolism and thrombosis of other arteries	0.792	0.208	0.000
J37.0 Chronic laryngitis	0.792	0.208	0.000
E14.6 With other specified complications	0.791	0.208	0.000
J32 Chronic sinusitis	0.791	0.209	0.000
M06.9 Rheumatoid arthritis, unspecified	0.791	0.209	0.000
E10.7 With multiple complications	0.791	0.209	0.000
W05 Fall involving wheelchair	0.791	0.209	0.000
T20 Burn and corrosion of head and neck	0.789	0.211	0.000
D86.1 Sarcoidosis of lymph nodes	0.787	0.212	0.000
X23 Contact with hornets, wasps and bees	0.787	0.213	0.000
E29 Testicular dysfunction	0.786	0.214	0.000
D61.0 Constitutional aplastic anaemia	0.786	0.214	0.000
E03.8 Other specified hypothyroidism	0.785	0.215	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.784	0.216	0.000
E31 Polyglandular dysfunction	0.783	0.217	0.000
M60 Myositis	0.782	0.218	0.000
W14 Fall from tree	0.782	0.218	0.000
M33 Dermatopolymyositis	0.782	0.218	0.000
Y42.2 Antithyroid drugs	0.781	0.219	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.781	0.219	0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified	0.781	0.219	0.000
M18 Arthrosis of first carpometacarpal joint	0.781	0.219	0.000
M62.82 Other specified disorders of muscle (Upper arm)	0.779	0.221	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.779	0.221	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.779	0.221	0.000
D61.1 Drug-induced aplastic anaemia	0.778	0.222	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.777	0.223	0.000
S20.8 Superficial injuries of other and unspecified parts of thorax	0.777	0.223	0.000
A48 Other bacterial diseases, not elsewhere classified	0.776	0.224	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.776	0.224	0.000
B44 Aspergillosis	0.775	0.225	0.000
I12.9 Hypertensive renal disease without renal failure	0.775	0.225	0.000
C18.9 Colon, unspecified	0.775	0.225	0.000
S42 Fracture of shoulder and upper arm	0.775	0.225	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.774	0.225	0.001
W50-W64 Exposure to animate mechanical forces	0.774	0.226	0.000
T23 Burn and corrosion of wrist and hand	0.774	0.226	0.000
D69 Purpura and other haemorrhagic conditions	0.774	0.226	0.000
V40-V49 Car occupant injured in transport accident	0.772	0.228	0.000
G35 Multiple sclerosis	0.772	0.228	0.000
C83.0 Small cell (diffuse)	0.772	0.228	0.000
M25.9 Joint disorder, unspecified	0.770	0.230	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.770	0.230	0.000
E10.0 With coma	0.770	0.230	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.769	0.231	0.000
J33.8 Other polyp of sinus	0.769	0.231	0.000
E88 Other metabolic disorders	0.768	0.232	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.767	0.233	0.000
E23 Hypofunction and other disorders of pituitary gland	0.766	0.234	0.000
M34.1 CR(E)ST syndrome	0.765	0.235	0.000
M22.3 Other derangements of patella	0.764	0.236	0.000
M62.81 Other specified disorders of muscle (Shoulder region)	0.764	0.236	0.000
T00-T07 Injuries involving multiple body regions	0.763	0.237	0.000
B90-B94 Sequelae of infectious and parasitic diseases	0.763	0.237	0.000
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.762	0.238	0.000
M17.1 Other primary gonarthrosis	0.761	0.239	0.000
A63.0 Anogenital (venereal) warts	0.761	0.239	0.000
G51.9 Disorder of facial nerve, unspecified	0.758	0.242	0.000
E20 Hypoparathyroidism	0.758	0.242	0.000
S21 Open wound of thorax	0.758	0.242	0.000
S05.8 Other injuries of eye and orbit	0.757	0.243	0.000
K76.9 Liver disease, unspecified	0.757	0.243	0.000
M24.6 Ankylosis of joint	0.757	0.243	0.000
M32.1 Systemic lupus erythematosus with organ or system involvement	0.757	0.243	0.000
E55 Vitamin D deficiency	0.756	0.244	0.000
I98.2 Oesophageal varices in diseases classified elsewhere	0.756	0.244	0.000
E16.1 Other hypoglycaemia	0.755	0.245	0.000
J40-J47 Chronic lower respiratory diseases	0.755	0.245	0.000
E10.6 With other specified complications	0.753	0.247	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.752	0.248	0.000
W19.9 Unspecified place	0.752	0.248	0.000
M21 Other acquired deformities of limbs	0.752	0.248	0.000
H04 Disorders of lachrymal system	0.749	0.251	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.747	0.253	0.000
L10-L14 Bullous disorders	0.746	0.253	0.001
C16.3 Pyloric antrum	0.747	0.253	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.746	0.254	0.000
H05.0 Acute inflammation of orbit	0.745	0.254	0.000
A15-A19 Tuberculosis	0.745	0.255	0.000
D83.9 Common variable immunodeficiency, unspecified	0.745	0.255	0.000
K72.1 Chronic hepatic failure	0.744	0.255	0.000
W13 Fall from, out of or through building or structure	0.744	0.256	0.000
C81.1 Nodular sclerosis	0.743	0.257	0.000
V90-V94 Water transport accidents	0.743	0.257	0.000
I11 Hypertensive heart disease	0.743	0.257	0.000
M35.3 Polymyalgia rheumatica	0.743	0.257	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.742	0.258	0.000
M86-M90 Other osteopathies	0.741	0.259	0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.741	0.259	0.000
H31 Other disorders of choroid	0.740	0.260	0.000
E14.5 With peripheral circulatory complications	0.739	0.261	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.738	0.262	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.737	0.263	0.000
M65-M68 Disorders of synovium and tendon	0.736	0.264	0.000
X10-X19 Contact with heat and hot substances	0.734	0.266	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.734	0.266	0.000
W19.3 Sports and athletics area	0.732	0.268	0.000
W03 Other fall on same level due to collision with, or pushing by, another person	0.732	0.268	0.000
X58 Exposure to other specified factors	0.731	0.269	0.000
C88.0 Waldenstrom's macroglobulinaemia	0.731	0.269	0.000
V09 Pedestrian injured in other and unspecified transport accidents	0.730	0.270	0.000
Q50-Q56 Congenital malformations of genital organs	0.730	0.270	0.000
D84 Other immunodeficiencies	0.729	0.270	0.000
E58 Dietary calcium deficiency	0.729	0.271	0.000
L13 Other bullous disorders	0.728	0.271	0.000
A65-A69 Other spirochaetal diseases	0.728	0.272	0.000
J32.0 Chronic maxillary sinusitis	0.727	0.273	0.000
Y59 Other and unspecified vaccines and biological substances	0.727	0.273	0.000
C93 Monocytic leukaemia	0.727	0.273	0.000
I74.5 Embolism and thrombosis of iliac artery	0.727	0.273	0.000
G59 Mononeuropathy in diseases classified elsewhere	0.727	0.273	0.000
M24.7 Protrusio acetabuli	0.726	0.274	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.726	0.274	0.000
J44 Other chronic obstructive pulmonary disease	0.726	0.274	0.000
E61 Deficiency of other nutrient elements	0.725	0.275	0.000
J82 Pulmonary eosinophilia, not elsewhere classified	0.724	0.276	0.000
S01.4 Open wound of cheek and temporomandibular area	0.724	0.276	0.000
H43.9 Disorder of vitreous body, unspecified	0.723	0.277	0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]	0.722	0.278	0.000
G51.0 Bell's palsy	0.721	0.279	0.000
X00-X09 Exposure to smoke, fire and flames	0.721	0.279	0.000
M17.3 Other posttraumatic gonarthrosis	0.721	0.279	0.000
B85-B89 Pediculosis, acariasis and other infestations	0.720	0.280	0.000
M31 Other necrotising vasculopathies	0.720	0.280	0.000
M62.83 Other specified disorders of muscle (Forearm)	0.720	0.280	0.000
D50 Iron deficiency anaemia	0.720	0.280	0.000
E27.9 Disorder of adrenal gland, unspecified	0.719	0.280	0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.720	0.280	0.000
M22.0 Recurrent dislocation of patella	0.719	0.281	0.000
D86.3 Sarcoidosis of skin	0.719	0.281	0.000
H25-H28 Disorders of lens	0.718	0.282	0.000
M15 Polyarthrosis	0.718	0.282	0.000
B02 Zoster [herpes zoster]	0.717	0.283	0.000
E05.5 Thyroid crisis or storm	0.717	0.283	0.000
E05.4 Thyrotoxicosis factitia	0.717	0.283	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.717	0.283	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.717	0.283	0.000
E00 Congenital iodine-deficiency syndrome	0.717	0.283	0.000
E12 Malnutrition-related diabetes mellitus	0.717	0.283	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
E03.5 Myxoedema coma	0.717	0.283	0.000
E03.4 Atrophy of thyroid (acquired)	0.717	0.283	0.000
E03.3 Postinfectious hypothyroidism	0.717	0.283	0.000
E03.1 Congenital hypothyroidism without goitre	0.717	0.283	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.717	0.283	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.717	0.283	0.000
M35.8 Other specified systemic involvement of connective tissue	0.717	0.283	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.717	0.283	0.000
M35.5 Multifocal fibrosclerosis	0.717	0.283	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.717	0.283	0.000
H32 Chorioretinal disorders in diseases classified elsewhere	0.717	0.283	0.000
H36.8 Other retinal disorders in diseases classified elsewhere	0.717	0.283	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.717	0.283	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.717	0.283	0.000
E16.4 Abnormal secretion of gastrin	0.717	0.283	0.000
E16.3 Increased secretion of glucagon	0.717	0.283	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.717	0.283	0.000
E15 Nondiabetic hypoglycaemic coma	0.717	0.283	0.000
D82 Immunodeficiency associated with other major defects	0.717	0.283	0.000
D81 Combined immunodeficiencies	0.717	0.283	0.000
E14.7 With multiple complications	0.717	0.283	0.000
E14.0 With coma	0.717	0.283	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.717	0.283	0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.717	0.283	0.000
A75-A79 Rickettsioses	0.717	0.283	0.000
A70-A74 Other diseases caused by chlamydiae	0.717	0.283	0.000
A20-A28 Certain zoonotic bacterial diseases	0.717	0.283	0.000
C91.1 Chronic lymphocytic leukaemia	0.717	0.283	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.716	0.284	0.000
E32 Diseases of thymus	0.716	0.284	0.000
E30 Disorders of puberty, not elsewhere classified	0.716	0.284	0.000
E25 Adrenogenital disorders	0.716	0.284	0.000
I00-I02 Acute rheumatic fever	0.716	0.284	0.000
E27.5 Adrenomedullary hyperfunction	0.716	0.284	0.000
E27.0 Other adrenocortical overactivity	0.716	0.284	0.000
L13.0 Dermatitis herpetiformis	0.716	0.284	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.716	0.284	0.000
D64.4 Congenital dyserythropoietic anaemia	0.715	0.284	0.000
D64.3 Other sideroblastic anaemias	0.715	0.284	0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.715	0.284	0.000
D64.1 Secondary sideroblastic anaemia due to disease	0.715	0.284	0.000
D64.0 Hereditary sideroblastic anaemia	0.715	0.284	0.000
S42.1 Fracture of scapula	0.715	0.285	0.000
G31.8 Other specified degenerative diseases of nervous system	0.714	0.286	0.000
M00 Pyogenic arthritis	0.714	0.286	0.000
M24.51 Contracture of joint (Shoulder region)	0.713	0.287	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.713	0.287	0.000
C94 Other leukaemias of specified cell type	0.713	0.287	0.000
C86 Other specified types of T/NK-cell lymphoma	0.713	0.287	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.712	0.288	0.000
K77 Liver disorders in diseases classified elsewhere	0.712	0.288	0.000
K71 Toxic liver disease	0.712	0.288	0.000
B16 Acute hepatitis B	0.712	0.288	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.712	0.288	0.000
M22.8 Other disorders of patella	0.712	0.288	0.000
M25.4 Effusion of joint	0.711	0.289	0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.710	0.290	0.000
C85.0 Lymphosarcoma	0.710	0.290	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.710	0.290	0.000
S10-S19 Injuries to the neck	0.709	0.291	0.000
Y35-Y36 Legal intervention and operations of war	0.709	0.291	0.000
Y10-Y34 Event of undetermined intent	0.709	0.291	0.000
X85-X99 Assault	0.709	0.291	0.000
X30-X39 Exposure to forces of nature	0.709	0.291	0.000
W75-W84 Other accidental threats to breathing	0.709	0.291	0.000
W65-W74 Accidental drowning and submersion	0.709	0.291	0.000
V95-V97 Air and space transport accidents	0.709	0.291	0.000
V70-V79 Bus occupant injured in transport accident	0.709	0.291	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.709	0.291	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.709	0.291	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.709	0.291	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.709	0.291	0.000
K50-K52 Noninfective enteritis and colitis	0.628	0.291	0.081
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.708	0.292	0.000
H34.9 Retinal vascular occlusion, unspecified	0.708	0.292	0.000
G50 Disorders of trigeminal nerve	0.708	0.292	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.708	0.292	0.000
B18.9 Chronic viral hepatitis, unspecified	0.707	0.293	0.000
C25 Malignant neoplasm of pancreas	0.707	0.293	0.000
K75.2 Nonspecific reactive hepatitis	0.706	0.294	0.000
K75.1 Phlebitis of portal vein	0.706	0.294	0.000
H03.8 Involvement of eyelid in other diseases classified elsewhere	0.706	0.294	0.000
C01 Malignant neoplasm of base of tongue	0.705	0.295	0.000
M24.23 Disorder of ligament (Forearm)	0.705	0.295	0.000
B48 Other mycoses, not elsewhere classified	0.704	0.296	0.000
B47 Mycetoma	0.704	0.296	0.000
B46 Zygomycosis	0.704	0.296	0.000
B45 Cryptococcosis	0.704	0.296	0.000
B43 Chromomycosis and phaeomycotic abscess	0.704	0.296	0.000
B42 Sporotrichosis	0.704	0.296	0.000
B41 Paracoccidioidomycosis	0.704	0.296	0.000
B40 Blastomycosis	0.704	0.296	0.000
B39 Histoplasmosis	0.704	0.296	0.000
B38 Coccidioidomycosis	0.704	0.296	0.000
H16 Keratitis	0.704	0.296	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations