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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3132469
log Bayes Factor = 98.3432
Chromosome 6   position 31,456,567  (GRCh37) Explore rs3132469 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E78.0 Pure hypercholesterolaemia
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
I10 Essential (primary) hypertension
0.000 0.000 1.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
I10-I15 Hypertensive diseases
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
Chapter IX Diseases of the circulatory system
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
I25.1 Atherosclerotic heart disease
0.000 0.000 1.000
I20 Angina pectoris
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.001 0.999
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.001 0.999
M05-M14 Inflammatory polyarthropathies
0.000 0.001 0.999
E14.9 Without complications
0.000 0.001 0.999
# Top node
0.000 0.001 0.999
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.001 0.999
I20.9 Angina pectoris, unspecified
0.000 0.001 0.999
L40.5 Arthropathic psoriasis
0.000 0.001 0.999
L40-L45 Papulosquamous disorders
0.000 0.001 0.999
M70-M79 Other soft tissue disorders
0.000 0.002 0.998
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.004 0.996
M45 Ankylosing spondylitis
0.000 0.004 0.996
M45-M49 Spondylopathies
0.000 0.004 0.996
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.005 0.995
I25.2 Old myocardial infarction
0.000 0.005 0.995
E70-E90 Metabolic disorders
0.000 0.006 0.994
M75 Shoulder lesions
0.000 0.006 0.994
Chapter VII Diseases of the eye and adnexa
0.000 0.006 0.994
E10.1 With ketoacidosis
0.000 0.006 0.994
H30-H36 Disorders of choroid and retina
0.000 0.007 0.993
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.008 0.992
I22 Subsequent myocardial infarction
0.000 0.008 0.992
L43 Lichen planus
0.000 0.011 0.989
M75.0 Adhesive capsulitis of shoulder
0.000 0.012 0.988
E14.3 With ophthalmic complications
0.000 0.012 0.988
H36 Retinal disorders in diseases classified elsewhere
0.000 0.015 0.985
I25.5 Ischaemic cardiomyopathy
0.000 0.017 0.983
E10.4 With neurological complications
0.000 0.017 0.983
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.019 0.981
H36.0 Diabetic retinopathy
0.000 0.020 0.980
G35-G37 Demyelinating diseases of the central nervous system
0.980 0.020 0.000
M75.4 Impingement syndrome of shoulder
0.000 0.020 0.980
L43.9 Lichen planus, unspecified
0.000 0.021 0.979
G37 Other demyelinating diseases of central nervous system
0.974 0.026 0.000
I12 Hypertensive renal disease
0.000 0.031 0.969
H35 Other retinal disorders
0.000 0.032 0.968
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.033 0.967
G37.9 Demyelinating disease of central nervous system, unspecified
0.963 0.037 0.000
H43-H45 Disorders of vitreous body and globe
0.000 0.037 0.963
H25-H28 Disorders of lens
0.000 0.037 0.963
I20.0 Unstable angina
0.000 0.037 0.963
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.042 0.958
H35.8 Other specified retinal disorders
0.000 0.046 0.954
I24 Other acute ischaemic heart diseases
0.000 0.046 0.954
H43 Disorders of vitreous body
0.000 0.051 0.949
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.052 0.948
I21 Acute myocardial infarction
0.000 0.057 0.943
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.058 0.942
H25 Senile cataract
0.000 0.065 0.935
E78.2 Mixed hyperlipidaemia
0.000 0.066 0.934
M79 Other soft tissue disorders, not elsewhere classified
0.000 0.071 0.929
E05.9 Thyrotoxicosis, unspecified
0.000 0.076 0.924
E78.8 Other disorders of lipoprotein metabolism
0.000 0.083 0.917
M79.6 Pain in limb
0.000 0.085 0.915
I12.9 Hypertensive renal disease without renal failure
0.000 0.088 0.912
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.092 0.908
H25.1 Senile nuclear cataract
0.000 0.094 0.906
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.095 0.905
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.095 0.905
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.105 0.895
H43.3 Other vitreous opacities
0.000 0.111 0.889
M05 Seropositive rheumatoid arthritis
0.000 0.117 0.883
M70 Soft tissue disorders related to use, overuse and pressure
0.000 0.118 0.882
M79.65 Pain in limb (Pelvic region and thigh)
0.000 0.119 0.881
H27 Other disorders of lens
0.000 0.122 0.878
I15 Secondary hypertension
0.000 0.125 0.875
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.127 0.873
H43.8 Other disorders of vitreous body
0.000 0.130 0.870
E10.2 With renal complications
0.000 0.130 0.870
E13 Other specified diabetes mellitus
0.000 0.133 0.867
G37.8 Other specified demyelinating diseases of central nervous system
0.866 0.134 0.000
E10.5 With peripheral circulatory complications
0.000 0.135 0.865
I12.0 Hypertensive renal disease with renal failure
0.000 0.136 0.864
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.138 0.862
M06.3 Rheumatoid nodule
0.000 0.145 0.855
I21.4 Acute subendocardial myocardial infarction
0.000 0.149 0.851
E10.8 With unspecified complications
0.000 0.149 0.851
M07 Psoriatic and enteropathic arthropathies
0.000 0.152 0.848
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.161 0.839
L40.8 Other psoriasis
0.000 0.164 0.836
E07 Other disorders of thyroid
0.000 0.165 0.835
E11.2 With renal complications
0.000 0.166 0.834
H35.4 Peripheral retinal degeneration
0.000 0.168 0.832
E11.1 With ketoacidosis
0.000 0.169 0.831
I21.9 Acute myocardial infarction, unspecified
0.000 0.170 0.830
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.173 0.827
E74 Other disorders of carbohydrate metabolism
0.000 0.176 0.824
L43.8 Other lichen planus
0.000 0.180 0.820
E16 Other disorders of pancreatic internal secretion
0.000 0.181 0.819
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.181 0.819
E11.0 With coma
0.000 0.181 0.819
E10.6 With other specified complications
0.000 0.189 0.811
H43.9 Disorder of vitreous body, unspecified
0.000 0.191 0.809
M79.62 Pain in limb (Upper arm)
0.000 0.192 0.808
E11.5 With peripheral circulatory complications
0.000 0.194 0.806
M79.1 Myalgia
0.000 0.200 0.800
L40.0 Psoriasis vulgaris
0.000 0.202 0.798
K90 Intestinal malabsorption
0.000 0.203 0.797
E40-E46 Malnutrition
0.000 0.205 0.795
H33 Retinal detachments and breaks
0.000 0.212 0.788
I25.3 Aneurysm of heart
0.000 0.212 0.788
M79.7 Fibromyalgia
0.000 0.217 0.783
I15.1 Hypertension secondary to other renal disorders
0.000 0.218 0.782
M70.4 Prepatellar bursitis
0.000 0.220 0.780
E13.9 Without complications
0.000 0.228 0.772
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.228 0.772
E78.1 Pure hyperglyceridaemia
0.000 0.229 0.771
E83 Disorders of mineral metabolism
0.695 0.234 0.071
M75.2 Bicipital tendinitis
0.000 0.235 0.765
I23 Certain current complications following acute myocardial infarction
0.000 0.236 0.764
M91-M94 Chondropathies
0.000 0.238 0.762
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.240 0.760
E10.0 With coma
0.000 0.241 0.759
M79.67 Pain in limb (Ankle and foot)
0.000 0.242 0.758
M79.60 Pain in limb (Multiple sites)
0.000 0.242 0.758
H27.8 Other specified disorders of lens
0.000 0.243 0.757
H27.0 Aphakia
0.000 0.243 0.757
I24.8 Other forms of acute ischaemic heart disease
0.000 0.251 0.749
M79.64 Pain in limb (Hand)
0.000 0.252 0.748
H35.5 Hereditary retinal dystrophy
0.000 0.254 0.746
H25.9 Senile cataract, unspecified
0.000 0.258 0.742
E16.2 Hypoglycaemia, unspecified
0.000 0.258 0.742
M79.63 Pain in limb (Forearm)
0.000 0.259 0.741
M07.3 Other psoriatic arthropathies
0.000 0.261 0.739
H34 Retinal vascular occlusions
0.000 0.262 0.738
M06.34 Rheumatoid nodule (Hand)
0.000 0.262 0.738
E11.4 With neurological complications
0.000 0.265 0.735
H30 Chorioretinal inflammation
0.000 0.267 0.733
M49 Spondylopathies in diseases classified elsewhere
0.000 0.268 0.732
H25.8 Other senile cataract
0.000 0.271 0.729
H35.6 Retinal haemorrhage
0.000 0.275 0.725
H55-H59 Other disorders of eye and adnexa
0.000 0.278 0.722
H43.2 Crystalline deposits in vitreous body
0.000 0.279 0.721
E85 Amyloidosis
0.000 0.280 0.719
M11 Other crystal arthropathies
0.000 0.281 0.719
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.281 0.719
H35.9 Retinal disorder, unspecified
0.000 0.281 0.719
E11.6 With other specified complications
0.000 0.282 0.717
H33.0 Retinal detachment with retinal break
0.000 0.283 0.717
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.3 Pustulosis palmaris et plantaris
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
I13 Hypertensive heart and renal disease
0.000 0.283 0.717
E14.8 With unspecified complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.5 With peripheral circulatory complications
0.000 0.283 0.717
E14.4 With neurological complications
0.000 0.283 0.717
E14.2 Withrenal complications
0.000 0.283 0.717
E14.1 With ketoacidosis
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
I00-I02 Acute rheumatic fever
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.284 0.716
M08 Juvenile arthritis
0.000 0.284 0.716
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.284 0.716
E07.9 Disorder of thyroid, unspecified
0.000 0.284 0.716
E78.6 Lipoprotein deficiency
0.000 0.284 0.716
E78.3 Hyperchylomicronaemia
0.000 0.284 0.716
L44 Other papulosquamous disorders
0.000 0.284 0.716
L41 Parapsoriasis
0.000 0.284 0.716
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.284 0.716
M73 Soft tissue disorders in diseases classified elsewhere
0.000 0.285 0.715
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.286 0.714
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.286 0.714
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.286 0.714
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.286 0.714
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.286 0.714
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.286 0.714
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.286 0.714
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.286 0.714
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.713 0.287 0.000
E79 Disorders of purine and pyrimidine metabolism
0.000 0.287 0.713
E77 Disorders of glycoprotein metabolism
0.000 0.287 0.713
E76 Disorders of glycosaminoglycan metabolism
0.000 0.287 0.713
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.287 0.713
E72 Other disorders of amino-acid metabolism
0.000 0.287 0.713
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.287 0.713
E70 Disorders of aromatic amino-acid metabolism
0.000 0.287 0.713
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.287 0.713
M75.8 Other shoulder lesions
0.000 0.287 0.713
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.288 0.712
M06.4 Inflammatory polyarthropathy
0.000 0.288 0.712
L42 Pityriasis rosea
0.000 0.289 0.711
M79.79 Fibromyalgia (Site unspecified)
0.000 0.290 0.710
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.290 0.710
M70.6 Trochanteric bursitis
0.000 0.290 0.710
L43.3 Subacute (active) lichen planus
0.000 0.291 0.709
L43.2 Lichenoid drug reaction
0.000 0.291 0.709
L43.1 Bullous lichen planus
0.000 0.291 0.709
L43.0 Hypertrophic lichen planus
0.000 0.291 0.709
I11 Hypertensive heart disease
0.000 0.291 0.709
E11.3 With ophthalmic complications
0.000 0.292 0.708
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.293 0.707
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.293 0.706
M70.46 Prepatellar bursitis-Lower Leg
0.000 0.294 0.706
H35.2 Other proliferative retinopathy
0.000 0.297 0.703
G36 Other acute disseminated demyelination
0.703 0.297 0.000
M79.18 Myalgia (Other)
0.000 0.298 0.702
E14.6 With other specified complications
0.000 0.298 0.702
M75.3 Calcific tendinitis of shoulder
0.000 0.298 0.702
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.298 0.701
G37.5 Concentric sclerosis [Balo]
0.698 0.301 0.000
G37.4 Subacute necrotising myelitis
0.698 0.301 0.000
G37.2 Central pontine myelinolysis
0.698 0.301 0.000
G37.1 Central demyelination of corpus callosum
0.698 0.301 0.000
G37.0 Diffuse sclerosis
0.698 0.301 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.302 0.698
M14 Arthropathies in other diseases classified elsewhere
0.000 0.302 0.697
H35.1 Retinopathy of prematurity
0.000 0.306 0.694
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.000 0.309 0.691
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.000 0.309 0.691
M71 Other bursopathies
0.000 0.311 0.688
I22.8 Subsequent myocardial infarction of other sites
0.000 0.313 0.687
M70.5 Other bursitis of knee
0.000 0.319 0.681
H43.0 Vitreous prolapse
0.000 0.319 0.681
E05.5 Thyroid crisis or storm
0.000 0.320 0.680
E05.4 Thyrotoxicosis factitia
0.000 0.320 0.680
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.320 0.680
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.320 0.680
M79.9 Soft tissue disorder, unspecified
0.000 0.322 0.678
I20.1 Angina pectoris with documented spasm
0.000 0.323 0.677
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.324 0.676
H25.2 Senile cataract, morgagnian type
0.000 0.330 0.670
H35.7 Separation of retinal layers
0.000 0.330 0.670
K90-K93 Other diseases of the digestive system
0.000 0.333 0.667
M79.3 Panniculitis, unspecified
0.000 0.334 0.666
M79.69 Pain in limb (Site unspecified)
0.000 0.334 0.666
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.336 0.664
E06 Thyroiditis
0.000 0.336 0.664
E84 Cystic fibrosis
0.000 0.336 0.664
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.337 0.663
E83.3 Disorders of phosphorus metabolism
0.644 0.338 0.018
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.342 0.658
Chapter XI Diseases of the digestive system
0.000 0.343 0.657
M77 Other enthesopathies
0.000 0.345 0.655
E11.8 With unspecified complications
0.000 0.349 0.651
E78.4 Other hyperlipidaemia
0.000 0.351 0.649
H35.0 Background retinopathy and retinal vascular changes
0.000 0.351 0.649
E05.8 Other thyrotoxicosis
0.000 0.352 0.648
M76 Enthesopathies of lower limb, excluding foot
0.000 0.352 0.648
M94 Other disorders of cartilage
0.000 0.352 0.648
E46 Unspecified protein-energy malnutrition
0.000 0.352 0.648
M79.2 Neuralgia and neuritis, unspecified
0.000 0.354 0.646
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.358 0.642
E15 Nondiabetic hypoglycaemic coma
0.000 0.358 0.641
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.359 0.641
I15.9 Seconday hypertension, unspecified
0.000 0.361 0.639
M79.68 Pain in limb (Other)
0.000 0.362 0.638
M05.8 Other seropositive rheumatoid arthritis
0.000 0.367 0.633
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.367 0.633
M05.1 Rheumatoid lung disease
0.000 0.367 0.633
M05.0 Felty's syndrome
0.000 0.367 0.633
M70.9 Unspecified soft tissue disorder related to use, overuse and pressure
0.000 0.367 0.633
M70.8 Other soft tissue disorders related to use, overuse and pressure
0.000 0.367 0.633
M70.3 Other bursitis of elbow
0.000 0.367 0.633
M70.1 Bursitis of hand
0.000 0.367 0.633
M70.0 Chronic crepitant synovitis of hand and wrist
0.000 0.367 0.633
E78.5 Hyperlipidaemia, unspecified
0.000 0.370 0.630
H27.9 Disorder of lens, unspecified
0.000 0.371 0.629
I15.8 Other secondary hypertension
0.000 0.372 0.628
I15.2 Hypertension secondary to endocrine disorders
0.000 0.372 0.628
I15.0 Renovascular hypertension
0.000 0.372 0.628
I24.1 Dressler's syndrome
0.000 0.374 0.626
K70-K77 Diseases of liver
0.000 0.375 0.625
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.377 0.622
H46-H48 Disorders of optic nerve and visual pathways
0.000 0.378 0.622
E13.8 With unspecified complications
0.000 0.378 0.622
E13.7 With multiple complications
0.000 0.378 0.622
E13.6 With other specified complications
0.000 0.378 0.622
E13.5 With peripheral circulatory complications
0.000 0.378 0.622
E13.4 With neurological complications
0.000 0.378 0.622
E13.3 With ophthalmic complications
0.000 0.378 0.622
E13.2 With renal complications
0.000 0.378 0.622
E13.1 With ketoacidosis
0.000 0.378 0.622
E13.0 With coma
0.000 0.378 0.622
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.379 0.621
H27.1 Dislocation of lens
0.000 0.382 0.618
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.384 0.615
M79.4 Hypertrophy of (infrapatellar) fat pad
0.000 0.385 0.615
L10-L14 Bullous disorders
0.000 0.386 0.613
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.000 0.386 0.613
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.387 0.613
M06.38 Rheumatoid nodule (Other)
0.000 0.387 0.613
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.387 0.613
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.387 0.613
M06.33 Rheumatoid nodule (Forearm)
0.000 0.387 0.613
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.387 0.613
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.387 0.613
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.387 0.613
H55 Nystagmus and other irregular eye movements
0.000 0.387 0.613
H33.2 Serous retinal detachment
0.000 0.388 0.612
R07.4 Chest pain, unspecified
0.000 0.388 0.612
H31 Other disorders of choroid
0.000 0.388 0.612
H43.1 Vitreous haemorrhage
0.000 0.389 0.611
E03.8 Other specified hypothyroidism
0.000 0.390 0.610
K74 Fibrosis and cirrhosis of liver
0.000 0.390 0.610
H33.1 Retinoschisis and retinal cysts
0.000 0.391 0.609
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.392 0.608
M07.6 Other enteropathic arthropathies
0.000 0.392 0.608
M07.5 Arthropathy in ulcerative colitis
0.000 0.392 0.608
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.392 0.608
M07.2 Psoriatic spondylitis
0.000 0.392 0.608
M07.1 Arthritis mutilans
0.000 0.392 0.608
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.392 0.608
M12 Other specific arthropathies
0.000 0.396 0.603
M79.19 Myalgia (Site unspecified)
0.000 0.397 0.603
H25.0 Senile incipient cataract
0.000 0.397 0.603
M79.15 Myalgia (Pelvic region and thigh)
0.000 0.397 0.602
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.399 0.601
E07.8 Other specified disorders of thyroid
0.000 0.399 0.601
E07.1 Dyshormogenetic goitre
0.000 0.401 0.599
E07.0 Hypersecretion of calcitonin
0.000 0.401 0.599
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.403 0.597
K90.9 Intestinal malabsorption, unspecified
0.000 0.405 0.595
I05-I09 Chronic rheumatic heart diseases
0.000 0.405 0.595
I23.8 Other current complications following acute myocardial infarction
0.000 0.406 0.594
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.409 0.590
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.409 0.590
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.409 0.590
E74.2 Disorders of galactose metabolism
0.000 0.409 0.590
E74.1 Disorders of fructose metabolism
0.000 0.409 0.590
E74.0 Glycogen storage disease
0.000 0.409 0.590
M79.16 Myalgia (Lower leg)
0.000 0.411 0.589
K74.3 Primary biliary cirrhosis
0.000 0.411 0.589
M70.2 Olecranon bursitis
0.000 0.412 0.588
I25.4 Coronary artery aneurysm
0.000 0.412 0.587
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.412 0.587
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.412 0.587
E16.4 Abnormal secretion of gastrin
0.000 0.412 0.587
E16.3 Increased secretion of glucagon
0.000 0.412 0.587
E16.1 Other hypoglycaemia
0.000 0.412 0.587
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.412 0.587
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.412 0.587
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.412 0.587
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.412 0.587
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.412 0.587
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.412 0.587
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.412 0.587
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.412 0.587
M79.11 Myalgia (Shoulder region)
0.000 0.413 0.587
M70.65 Trochanteric bursitis-Pelvic/Thigh
0.000 0.414 0.586
E85.9 Amyloidosis, unspecified
0.000 0.421 0.579
E50-E64 Other nutritional deficiencies
0.000 0.423 0.577
M70.7 Other bursitis of hip
0.000 0.423 0.577
M79.17 Myalgia (Ankle and foot)
0.000 0.426 0.574
M79.14 Myalgia (Hand)
0.000 0.426 0.574
M79.13 Myalgia (Forearm)
0.000 0.426 0.574
M79.12 Myalgia (Upper arm)
0.000 0.426 0.574
K90.3 Pancreatic steatorrhoea
0.000 0.429 0.571
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.429 0.571
K90.1 Tropical sprue
0.000 0.429 0.571
M46 Other inflammatory spondylopathies
0.000 0.429 0.571
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.430 0.570
E45 Retarded development following protein-energy malnutrition
0.000 0.430 0.570
E43 Unspecified severe protein-energy malnutrition
0.000 0.430 0.570
E42 Marasmic kwashiorkor
0.000 0.430 0.570
E41 Nutritional marasmus
0.000 0.430 0.570
E40 Kwashiorkor
0.000 0.430 0.570
H34.8 Other retinal vascular occlusions
0.000 0.430 0.570
K72 Hepatic failure, not elsewhere classified
0.000 0.433 0.567
H34.1 Central retinal artery occlusion
0.000 0.437 0.563
M75.9 Shoulder lesion, unspecified
0.000 0.437 0.562
M79.78 Fibromyalgia (Other)
0.000 0.439 0.561
M79.77 Fibromyalgia (Ankle and foot)
0.000 0.439 0.561
M79.76 Fibromyalgia (Lower leg)
0.000 0.439 0.561
M79.75 Fibromyalgia (Pelvic region and thigh)
0.000 0.439 0.561
M79.74 Fibromyalgia (Hand)
0.000 0.439 0.561
M79.73 Fibromyalgia (Forearm)
0.000 0.439 0.561
M79.72 Fibromyalgia (Upper arm)
0.000 0.439 0.561
M79.71 Fibromyalgia (Shoulder region)
0.000 0.439 0.561
E73 Lactose intolerance
0.001 0.441 0.559
M70.49 Prepatellar bursitis-Site unspec
0.000 0.441 0.559
M70.48 Prepatellar bursitis-Other
0.000 0.441 0.559
M70.47 Prepatellar bursitis-Ankle/Foot
0.000 0.441 0.559
M70.45 Prepatellar bursitis-Pelvic/Thigh
0.000 0.441 0.559
M70.44 Prepatellar bursitis-Hand
0.000 0.441 0.559
M70.43 Prepatellar bursitis-Forearm
0.000 0.441 0.559
M70.42 Prepatellar bursitis-Upper arm
0.000 0.441 0.559
M70.41 Prepatellar bursitis-Shldr region
0.000 0.441 0.559
M70.40 Prepatellar bursitis-Mult sites
0.000 0.441 0.559
E88 Other metabolic disorders
0.000 0.443 0.557
M05.2 Rheumatoid vasculitis
0.000 0.443 0.557
M11.2 Other chondrocalcinosis
0.000 0.446 0.554
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.449 0.551
M71.2 Synovial cyst of popliteal space [Baker]
0.000 0.449 0.551
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.451 0.549
E83.9 Disorder of mineral metabolism, unspecified
0.498 0.451 0.051
E83.8 Other disorders of mineral metabolism
0.498 0.451 0.051
E83.2 Disorders of zinc metabolism
0.498 0.451 0.051
E83.0 Disorders of copper metabolism
0.498 0.451 0.051
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.000 0.451 0.549
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.452 0.547
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.452 0.547
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.452 0.547
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.452 0.547
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.452 0.547
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.452 0.547
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.452 0.547
M79.5 Residual foreign body in soft tissue
0.000 0.453 0.547
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.000 0.454 0.546
J45 Asthma
0.000 0.454 0.546
H30.9 Chorioretinal inflammation, unspecified
0.000 0.454 0.546
E89.3 Postprocedural hypopituitarism
0.000 0.454 0.546
M49.5 Collapsed vertebra in diseases classified elsewhere
0.000 0.456 0.543
M91 Juvenile osteochondrosis of hip and pelvis
0.000 0.457 0.542
M94.8 Other specified disorders of cartilage
0.000 0.459 0.541
Chapter VIII Diseases of the ear and mastoid process
0.000 0.460 0.540
H33.4 Traction detachment of retina
0.000 0.460 0.540
H44 Disorders of globe
0.000 0.460 0.540
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.460 0.540
K90.8 Other intestinal malabsorption
0.000 0.461 0.538
M70.56 Other bursitis of knee-Lower Leg
0.000 0.463 0.537
M79.61 Pain in limb (Shoulder region)
0.000 0.464 0.536
M65-M68 Disorders of synovium and tendon
0.000 0.464 0.536
M07.38 Other psoriatic arthropathies (Other)
0.000 0.470 0.530
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.470 0.530
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.470 0.530
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.470 0.530
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.470 0.530
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.470 0.530
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.470 0.530
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.470 0.530
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.470 0.529
H34.0 Transient retinal artery occlusion
0.000 0.471 0.529
H30.8 Other chorioretinal inflammations
0.000 0.475 0.525
H30.2 Posterior cyclitis
0.000 0.475 0.525
H30.1 Disseminated chorioretinal inflammation
0.000 0.475 0.525
H30.0 Focal chorioretinal inflammation
0.000 0.475 0.525
M49.8 Spondylopathy in other diseases classified elsewhere
0.000 0.475 0.525
M49.4 Neuropathic spondylopathy
0.000 0.475 0.525
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere
0.000 0.475 0.525
M49.2 Enterobacterial spondylitis
0.000 0.475 0.525
M49.1 Brucella spondylitis
0.000 0.475 0.525
M49.0 Tuberculosis of spine
0.000 0.475 0.525
M60-M63 Disorders of muscles
0.000 0.477 0.523
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.477 0.523
M77.1 Lateral epicondylitis
0.000 0.478 0.522
H34.2 Other retinal artery occlusions
0.000 0.478 0.522
K73 Chronic hepatitis, not elsewhere classified
0.000 0.481 0.519
E85.8 Other amyloidosis
0.000 0.484 0.516
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.484 0.516
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.484 0.516
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.484 0.516
M11.9 Crystal arthropathy, unspecified
0.000 0.484 0.516
M11.1 Familial chondrocalcinosis
0.000 0.484 0.516
M11.0 Hydroxyapatite deposition disease
0.000 0.484 0.516
K74.5 Biliary cirrhosis, unspecified
0.000 0.485 0.515
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.486 0.514

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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