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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3132499
log Bayes Factor = 50.6464
Chromosome 6   position 31,207,920  (GRCh37) Explore rs3132499 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E78.0 Pure hypercholesterolaemia
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.001 0.999
I25.2 Old myocardial infarction
0.000 0.001 0.999
I25.1 Atherosclerotic heart disease
0.000 0.002 0.998
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.003 0.997
L40.5 Arthropathic psoriasis
0.000 0.004 0.996
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.004 0.996
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.009 0.991
I21 Acute myocardial infarction
0.000 0.015 0.985
E14 Unspecified diabetes mellitus
0.000 0.021 0.979
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.022 0.978
E10.3 With ophthalmic complications
0.000 0.023 0.977
L40-L45 Papulosquamous disorders
0.000 0.026 0.974
E70-E90 Metabolic disorders
0.000 0.027 0.973
I22 Subsequent myocardial infarction
0.000 0.027 0.973
I25.5 Ischaemic cardiomyopathy
0.000 0.028 0.972
I10 Essential (primary) hypertension
0.000 0.030 0.970
I10-I15 Hypertensive diseases
0.000 0.032 0.968
J45.9 Asthma, unspecified
0.000 0.033 0.967
E14.9 Without complications
0.000 0.035 0.965
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.036 0.964
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.047 0.953
I21.9 Acute myocardial infarction, unspecified
0.000 0.047 0.953
L43 Lichen planus
0.000 0.054 0.946
Chapter IX Diseases of the circulatory system
0.000 0.058 0.942
I12 Hypertensive renal disease
0.000 0.066 0.934
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.067 0.933
I21.4 Acute subendocardial myocardial infarction
0.000 0.067 0.933
I24 Other acute ischaemic heart diseases
0.000 0.068 0.932
L43.9 Lichen planus, unspecified
0.000 0.076 0.924
M06 Other rheumatoid arthritis
0.000 0.078 0.922
G35-G37 Demyelinating diseases of the central nervous system
0.914 0.086 0.000
E78.2 Mixed hyperlipidaemia
0.000 0.090 0.910
E11.0 With coma
0.000 0.103 0.896
E78.8 Other disorders of lipoprotein metabolism
0.000 0.105 0.895
I12.9 Hypertensive renal disease without renal failure
0.000 0.107 0.893
K51.9 Ulcerative colitis, unspecified
0.890 0.110 0.000
K51 Ulcerative colitis
0.888 0.112 0.000
G37 Other demyelinating diseases of central nervous system
0.887 0.113 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.123 0.877
E10.1 With ketoacidosis
0.000 0.135 0.865
E13 Other specified diabetes mellitus
0.000 0.146 0.854
G37.9 Demyelinating disease of central nervous system, unspecified
0.854 0.146 0.000
K90 Intestinal malabsorption
0.000 0.149 0.851
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.151 0.849
L40.8 Other psoriasis
0.000 0.153 0.847
M05-M14 Inflammatory polyarthropathies
0.000 0.155 0.845
E10.4 With neurological complications
0.000 0.155 0.845
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.156 0.844
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.156 0.844
E11.1 With ketoacidosis
0.000 0.158 0.842
M45 Ankylosing spondylitis
0.000 0.163 0.837
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.170 0.830
K51.3 Ulcerative (chronic) rectosigmoiditis
0.828 0.172 0.000
L40.0 Psoriasis vulgaris
0.000 0.179 0.821
E74 Other disorders of carbohydrate metabolism
0.000 0.179 0.821
I20 Angina pectoris
0.000 0.181 0.819
M45-M49 Spondylopathies
0.000 0.181 0.819
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.181 0.819
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.181 0.819
K51.8 Other ulcerative colitis
0.818 0.182 0.000
M70-M79 Other soft tissue disorders
0.000 0.191 0.809
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.193 0.807
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.193 0.807
# Top node
0.000 0.195 0.805
E10.0 With coma
0.000 0.201 0.799
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.202 0.798
E10.8 With unspecified complications
0.000 0.203 0.797
K51.4 Pseudopolyposis of colon
0.795 0.205 0.000
E78.5 Hyperlipidaemia, unspecified
0.000 0.209 0.791
M79 Other soft tissue disorders, not elsewhere classified
0.000 0.214 0.786
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.218 0.782
I12.0 Hypertensive renal disease with renal failure
0.000 0.219 0.781
I15 Secondary hypertension
0.000 0.220 0.780
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.220 0.780
E11.2 With renal complications
0.000 0.222 0.778
M75 Shoulder lesions
0.000 0.223 0.777
K51.5 Mucosal proctocolitis
0.775 0.225 0.000
E10.6 With other specified complications
0.000 0.226 0.774
M75.0 Adhesive capsulitis of shoulder
0.000 0.227 0.773
I20.9 Angina pectoris, unspecified
0.000 0.235 0.765
M79.6 Pain in limb
0.000 0.236 0.764
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.236 0.764
I25.3 Aneurysm of heart
0.000 0.243 0.757
M07 Psoriatic and enteropathic arthropathies
0.000 0.244 0.756
E10.5 With peripheral circulatory complications
0.000 0.245 0.755
K51.2 Ulcerative (chronic) proctitis
0.754 0.246 0.000
E11.6 With other specified complications
0.000 0.246 0.754
E13.9 Without complications
0.000 0.250 0.750
M79.65 Pain in limb (Pelvic region and thigh)
0.000 0.251 0.749
E78.1 Pure hyperglyceridaemia
0.000 0.254 0.746
E11.5 With peripheral circulatory complications
0.000 0.257 0.743
E14.3 With ophthalmic complications
0.000 0.258 0.742
M06.4 Inflammatory polyarthropathy
0.000 0.259 0.741
M79.1 Myalgia
0.000 0.260 0.740
M79.7 Fibromyalgia
0.000 0.264 0.736
M06.3 Rheumatoid nodule
0.000 0.265 0.735
I24.8 Other forms of acute ischaemic heart disease
0.000 0.268 0.732
G37.8 Other specified demyelinating diseases of central nervous system
0.727 0.273 0.000
E10.2 With renal complications
0.000 0.275 0.725
E16 Other disorders of pancreatic internal secretion
0.000 0.276 0.724
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.277 0.723
E78.4 Other hyperlipidaemia
0.000 0.282 0.718
E10.7 With multiple complications
0.000 0.283 0.717
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
I23 Certain current complications following acute myocardial infarction
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.283 0.717
Chapter VIII Diseases of the ear and mastoid process
0.000 0.284 0.716
L42 Pityriasis rosea
0.000 0.284 0.716
K90-K93 Other diseases of the digestive system
0.000 0.284 0.716
K58.0 Irritable bowel syndrome with diarrhoea
0.000 0.285 0.715
E78.6 Lipoprotein deficiency
0.000 0.286 0.714
E78.3 Hyperchylomicronaemia
0.000 0.286 0.714
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.287 0.713
I22.8 Subsequent myocardial infarction of other sites
0.000 0.287 0.713
M70 Soft tissue disorders related to use, overuse and pressure
0.000 0.287 0.713
I11 Hypertensive heart disease
0.000 0.287 0.713
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.288 0.712
M79.79 Fibromyalgia (Site unspecified)
0.000 0.289 0.711
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.294 0.706
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.294 0.706
L43.8 Other lichen planus
0.000 0.295 0.705
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.295 0.705
M07.3 Other psoriatic arthropathies
0.000 0.297 0.703
Chapter XI Diseases of the digestive system
0.000 0.297 0.703
E14.8 With unspecified complications
0.000 0.298 0.702
E14.7 With multiple complications
0.000 0.298 0.702
E14.6 With other specified complications
0.000 0.298 0.702
E14.5 With peripheral circulatory complications
0.000 0.298 0.702
E14.2 Withrenal complications
0.000 0.298 0.702
E14.1 With ketoacidosis
0.000 0.298 0.702
E14.0 With coma
0.000 0.298 0.702
K58 Irritable bowel syndrome
0.000 0.301 0.699
M79.18 Myalgia (Other)
0.000 0.301 0.699
L44 Other papulosquamous disorders
0.000 0.302 0.698
L41 Parapsoriasis
0.000 0.302 0.698
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.302 0.698
K55-K64 Other diseases of intestines
0.000 0.302 0.698
E79 Disorders of purine and pyrimidine metabolism
0.000 0.302 0.697
E77 Disorders of glycoprotein metabolism
0.000 0.302 0.697
E76 Disorders of glycosaminoglycan metabolism
0.000 0.302 0.697
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.302 0.697
E72 Other disorders of amino-acid metabolism
0.000 0.302 0.697
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.302 0.697
E70 Disorders of aromatic amino-acid metabolism
0.000 0.302 0.697
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.302 0.697
K57 Diverticular disease of intestine
0.000 0.306 0.694
I13 Hypertensive heart and renal disease
0.000 0.306 0.694
E11.4 With neurological complications
0.000 0.309 0.691
M05 Seropositive rheumatoid arthritis
0.000 0.316 0.684
K51.1 Ulcerative (chronic) ileocolitis
0.682 0.318 0.000
H60-H62 Diseases of external ear
0.000 0.319 0.681
K57.3 Diverticular disease of large intestine without perforation or abscess
0.000 0.320 0.680
L43.3 Subacute (active) lichen planus
0.000 0.322 0.678
L43.2 Lichenoid drug reaction
0.000 0.322 0.678
L43.1 Bullous lichen planus
0.000 0.322 0.678
L43.0 Hypertrophic lichen planus
0.000 0.322 0.678
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.325 0.675
E84 Cystic fibrosis
0.000 0.327 0.673
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.330 0.670
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.331 0.669
E40-E46 Malnutrition
0.000 0.333 0.667
K51.0 Ulcerative (chronic) enterocolitis
0.663 0.336 0.000
H60 Otitis externa
0.000 0.338 0.662
H65-H75 Diseases of middle ear and mastoid
0.000 0.339 0.661
M79.62 Pain in limb (Upper arm)
0.000 0.339 0.661
M06.8 Other specified rheumatoid arthritis
0.000 0.339 0.661
M06.2 Rheumatoid bursitis
0.000 0.339 0.661
M06.1 Adult-onset Still's disease
0.000 0.339 0.661
M49 Spondylopathies in diseases classified elsewhere
0.000 0.343 0.657
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.657 0.343 0.000
G36 Other acute disseminated demyelination
0.655 0.345 0.000
E14.4 With neurological complications
0.000 0.352 0.648
I15.1 Hypertension secondary to other renal disorders
0.000 0.354 0.646
M75.4 Impingement syndrome of shoulder
0.000 0.354 0.646
M70.4 Prepatellar bursitis
0.000 0.357 0.643
M75.2 Bicipital tendinitis
0.000 0.361 0.639
E85 Amyloidosis
0.000 0.362 0.638
G37.5 Concentric sclerosis [Balo]
0.636 0.364 0.000
G37.4 Subacute necrotising myelitis
0.636 0.364 0.000
G37.2 Central pontine myelinolysis
0.636 0.364 0.000
G37.1 Central demyelination of corpus callosum
0.636 0.364 0.000
G37.0 Diffuse sclerosis
0.636 0.364 0.000
K60 Fissure and fistula of anal and rectal regions
0.000 0.365 0.635
K90.8 Other intestinal malabsorption
0.000 0.365 0.634
M79.64 Pain in limb (Hand)
0.000 0.366 0.634
L40.3 Pustulosis palmaris et plantaris
0.000 0.368 0.632
E16.2 Hypoglycaemia, unspecified
0.000 0.369 0.631
K90.9 Intestinal malabsorption, unspecified
0.000 0.369 0.631
K57.8 Diverticular disease of intestine, part unspecified, with perforation and abscess
0.000 0.371 0.629
M46 Other inflammatory spondylopathies
0.000 0.373 0.627
H60.9 Otitis externa, unspecified
0.000 0.375 0.625
I24.1 Dressler's syndrome
0.000 0.378 0.622
K57.1 Diverticular disease of small intestine without perforation or abscess
0.000 0.379 0.621
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.381 0.619
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.381 0.619
I00-I02 Acute rheumatic fever
0.000 0.383 0.617
H71 Cholesteatoma of middle ear
0.000 0.385 0.615
E13.8 With unspecified complications
0.000 0.387 0.612
E13.7 With multiple complications
0.000 0.387 0.612
E13.6 With other specified complications
0.000 0.387 0.612
E13.5 With peripheral circulatory complications
0.000 0.387 0.612
E13.4 With neurological complications
0.000 0.387 0.612
E13.3 With ophthalmic complications
0.000 0.387 0.612
E13.2 With renal complications
0.000 0.387 0.612
E13.1 With ketoacidosis
0.000 0.387 0.612
E13.0 With coma
0.000 0.387 0.612
E83 Disorders of mineral metabolism
0.317 0.388 0.295
I25.4 Coronary artery aneurysm
0.000 0.389 0.611
K90.3 Pancreatic steatorrhoea
0.000 0.390 0.610
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.390 0.610
K90.1 Tropical sprue
0.000 0.390 0.610
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.392 0.608
E89.3 Postprocedural hypopituitarism
0.000 0.393 0.607
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.394 0.606
M08 Juvenile arthritis
0.000 0.394 0.606
K60.2 Anal fissure, unspecified
0.000 0.394 0.606
H74 Other disorders of middle ear and mastoid
0.000 0.395 0.605
M06.34 Rheumatoid nodule (Hand)
0.000 0.395 0.605
M79.60 Pain in limb (Multiple sites)
0.000 0.398 0.602
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.400 0.600
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.400 0.600
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.400 0.600
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.400 0.600
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.400 0.600
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.400 0.600
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.400 0.600
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.400 0.600
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.401 0.599
I20.0 Unstable angina
0.000 0.402 0.598
E15 Nondiabetic hypoglycaemic coma
0.000 0.405 0.595
M70.46 Prepatellar bursitis-Lower Leg
0.000 0.406 0.594
M79.67 Pain in limb (Ankle and foot)
0.000 0.406 0.594
E20-E35 Disorders of other endocrine glands
0.000 0.407 0.593
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.411 0.588
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.411 0.588
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.411 0.588
E74.2 Disorders of galactose metabolism
0.000 0.411 0.588
E74.1 Disorders of fructose metabolism
0.000 0.411 0.588
E74.0 Glycogen storage disease
0.000 0.411 0.588
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.412 0.588
K60.0 Acute anal fissure
0.000 0.412 0.588
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.418 0.582
M70.6 Trochanteric bursitis
0.000 0.419 0.581
M73 Soft tissue disorders in diseases classified elsewhere
0.000 0.420 0.580
M11 Other crystal arthropathies
0.000 0.422 0.578
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.423 0.577
M79.15 Myalgia (Pelvic region and thigh)
0.000 0.425 0.575
M77 Other enthesopathies
0.000 0.426 0.574
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.000 0.426 0.574
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.431 0.569
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.433 0.567
M79.3 Panniculitis, unspecified
0.000 0.437 0.563
H73 Other disorders of tympanic membrane
0.000 0.438 0.562
H60.3 Other infective otitis externa
0.000 0.439 0.561
I15.9 Seconday hypertension, unspecified
0.000 0.440 0.559
I15.8 Other secondary hypertension
0.000 0.440 0.559
I15.2 Hypertension secondary to endocrine disorders
0.000 0.440 0.559
I15.0 Renovascular hypertension
0.000 0.440 0.559
M75.8 Other shoulder lesions
0.000 0.443 0.557
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.444 0.556
E11.8 With unspecified complications
0.000 0.444 0.555
H74.8 Other specified disorders of middle ear and mastoid
0.000 0.446 0.554
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.446 0.554
M79.9 Soft tissue disorder, unspecified
0.000 0.448 0.552
M79.11 Myalgia (Shoulder region)
0.000 0.449 0.551
M79.63 Pain in limb (Forearm)
0.000 0.451 0.549
M79.4 Hypertrophy of (infrapatellar) fat pad
0.000 0.452 0.548
I20.1 Angina pectoris with documented spasm
0.000 0.456 0.544
E73 Lactose intolerance
0.001 0.457 0.542
M79.16 Myalgia (Lower leg)
0.000 0.457 0.543
M14 Arthropathies in other diseases classified elsewhere
0.000 0.457 0.542
M06.0 Seronegative rheumatoid arthritis
0.000 0.458 0.542
M07.5 Arthropathy in ulcerative colitis
0.000 0.458 0.542
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.458 0.542
M07.2 Psoriatic spondylitis
0.000 0.458 0.542
M07.1 Arthritis mutilans
0.000 0.458 0.542
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.458 0.542
M46.4 Discitis, unspecified
0.000 0.458 0.542
M49.5 Collapsed vertebra in diseases classified elsewhere
0.000 0.459 0.541
K57.5 Diverticular disease of both small and large intestine without perforation or abscess
0.000 0.468 0.532
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.469 0.531
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.469 0.531
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.469 0.531
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.469 0.531
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.469 0.531
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.469 0.531
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.469 0.531
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.469 0.531
M79.17 Myalgia (Ankle and foot)
0.000 0.470 0.530
M79.14 Myalgia (Hand)
0.000 0.470 0.530
M79.13 Myalgia (Forearm)
0.000 0.470 0.530
M79.12 Myalgia (Upper arm)
0.000 0.470 0.530
M12 Other specific arthropathies
0.000 0.470 0.530
M91-M94 Chondropathies
0.000 0.470 0.530
M79.19 Myalgia (Site unspecified)
0.000 0.471 0.529
K57.9 Diverticular disease of intestine, part unspecified, without perforation or abscess
0.000 0.472 0.528
M79.78 Fibromyalgia (Other)
0.000 0.472 0.527
M79.77 Fibromyalgia (Ankle and foot)
0.000 0.472 0.527
M79.76 Fibromyalgia (Lower leg)
0.000 0.472 0.527
M79.75 Fibromyalgia (Pelvic region and thigh)
0.000 0.472 0.527
M79.74 Fibromyalgia (Hand)
0.000 0.472 0.527
M79.73 Fibromyalgia (Forearm)
0.000 0.472 0.527
M79.72 Fibromyalgia (Upper arm)
0.000 0.472 0.527
M79.71 Fibromyalgia (Shoulder region)
0.000 0.472 0.527
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.473 0.527
M06.38 Rheumatoid nodule (Other)
0.000 0.473 0.527
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.473 0.527
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.473 0.527
M06.33 Rheumatoid nodule (Forearm)
0.000 0.473 0.527
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.473 0.527
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.473 0.527
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.473 0.527
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.475 0.525
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.478 0.522
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.478 0.522
H66 Suppurative and unspecified otitis media
0.000 0.479 0.521
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.481 0.519
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.481 0.519
E16.4 Abnormal secretion of gastrin
0.000 0.481 0.519
E16.3 Increased secretion of glucagon
0.000 0.481 0.519
E16.1 Other hypoglycaemia
0.000 0.481 0.519
E28 Ovarian dysfunction
0.000 0.481 0.519
M79.61 Pain in limb (Shoulder region)
0.000 0.481 0.519
H60.8 Other otitis externa
0.000 0.482 0.518
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.484 0.516
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
I23.8 Other current complications following acute myocardial infarction
0.000 0.486 0.514
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.486 0.514
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.486 0.514
E88 Other metabolic disorders
0.000 0.487 0.513
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.487 0.513
H60.1 Cellulitis of external ear
0.000 0.488 0.512
M70.9 Unspecified soft tissue disorder related to use, overuse and pressure
0.000 0.489 0.511
M70.8 Other soft tissue disorders related to use, overuse and pressure
0.000 0.489 0.511
M70.5 Other bursitis of knee
0.000 0.489 0.511
M70.1 Bursitis of hand
0.000 0.489 0.511
M70.0 Chronic crepitant synovitis of hand and wrist
0.000 0.489 0.511
E00-E07 Disorders of thyroid gland
0.000 0.493 0.507
M07.38 Other psoriatic arthropathies (Other)
0.000 0.496 0.504
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.496 0.504
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.496 0.504
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.496 0.504
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.496 0.504
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.496 0.504
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.496 0.504
M79.69 Pain in limb (Site unspecified)
0.000 0.498 0.502
K59 Other functional intestinal disorders
0.000 0.498 0.502
L41.9 Parapsoriasis, unspecified
0.000 0.499 0.501
L41.8 Other parapsoriasis
0.000 0.499 0.501
L41.5 Retiform parapsoriasis
0.000 0.499 0.501
L41.4 Large plaque parapsoriasis
0.000 0.499 0.501
L41.3 Small plaque parapsoriasis
0.000 0.499 0.501
L41.2 Lymphomatoid papulosis
0.000 0.499 0.501
L41.1 Pityriasis lichenoides chronica
0.000 0.499 0.501
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.499 0.501
L44.9 Papulosquamous disorder, unspecified
0.000 0.499 0.501
L44.8 Other specified papulosquamous disorders
0.000 0.499 0.501
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.499 0.501
L44.3 Lichen ruber moniliformis
0.000 0.499 0.501
L44.2 Lichen striatus
0.000 0.499 0.501
L44.1 Lichen nitidus
0.000 0.499 0.501
L44.0 Pityriasis rubra pilaris
0.000 0.499 0.501
K64 Haemorrhoids and perianal venous thrombosis
0.000 0.499 0.501
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.500 0.500
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.500 0.500
E70.3 Albinism
0.000 0.500 0.500
E70.2 Disorders of tyrosine metabolism
0.000 0.500 0.500
E70.1 Other hyperphenylalaninaemias
0.000 0.500 0.500
E70.0 Classical phenylketonuria
0.000 0.500 0.500
E71.3 Disorders of fatty-acid metabolism
0.000 0.500 0.500
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.500 0.500
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.500 0.500
E71.0 Maple-syrup-urine disease
0.000 0.500 0.500
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.500 0.500
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.500 0.500
E72.5 Disorders of glycine metabolism
0.000 0.500 0.500
E72.4 Disorders of ornithine metabolism
0.000 0.500 0.500
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.500 0.500
E72.2 Disorders of urea cycle metabolism
0.000 0.500 0.500
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.500 0.500
E72.0 Disorders of amino-acid transport
0.000 0.500 0.500
E75.6 Lipid storage disorder, unspecified
0.000 0.500 0.500
E75.5 Other lipid storage disorders
0.000 0.500 0.500
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.500 0.500
E75.3 Sphingolipidosis, unspecified
0.000 0.500 0.500
E75.2 Other sphingolipidosis
0.000 0.500 0.500
E75.1 Other gangliosidosis
0.000 0.500 0.500
E75.0 GM2 gangliosidosis
0.000 0.500 0.500
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.500 0.500
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.500 0.500
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.500 0.500
E76.2 Other mucopolysaccharidoses
0.000 0.500 0.500
E76.1 Mucopolysaccharidosis, type II
0.000 0.500 0.500
E76.0 Mucopolysaccharidosis, type I
0.000 0.500 0.500
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.500 0.500
E77.8 Other disorders of glycoprotein metabolism
0.000 0.500 0.500
E77.1 Defects in glycoprotein degradation
0.000 0.500 0.500
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.500 0.500
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.500 0.500
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.500 0.500
E79.1 Lesch-Nyhan syndrome
0.000 0.500 0.500
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.500 0.500
H74.4 Polyp of middle ear
0.000 0.500 0.500
K57.4 Diverticular disease of both small and large intestine with perforation and abscess
0.000 0.502 0.498
M07.6 Other enteropathic arthropathies
0.000 0.502 0.498
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.502 0.497
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.502 0.497
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.502 0.497
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.502 0.497
H66.3 Other chronic suppurative otitis media
0.000 0.508 0.492
M05.8 Other seropositive rheumatoid arthritis
0.000 0.509 0.491
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.509 0.491
M05.1 Rheumatoid lung disease
0.000 0.509 0.491
M05.0 Felty's syndrome
0.000 0.509 0.491
M79.10 Myalgia (Multiple sites)
0.000 0.510 0.490
H73.8 Other specified disorders of tympanic membrane
0.000 0.510 0.490
H60.5 Acute otitis externa, non-infective
0.000 0.510 0.490
E50-E64 Other nutritional deficiencies
0.000 0.510 0.489
M77.1 Lateral epicondylitis
0.000 0.510 0.489
K70-K77 Diseases of liver
0.000 0.511 0.489
I30-I52 Other forms of heart disease
0.000 0.512 0.488
M79.68 Pain in limb (Other)
0.000 0.512 0.487
M70.65 Trochanteric bursitis-Pelvic/Thigh
0.000 0.514 0.486
E28.2 Polycystic ovarian syndrome
0.000 0.514 0.486
M70.7 Other bursitis of hip
0.000 0.515 0.485
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.000 0.516 0.484
E84.8 Cystic fibrosis with other manifestations
0.000 0.517 0.483
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.517 0.483
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.517 0.483
L10-L14 Bullous disorders
0.000 0.517 0.482
M70.2 Olecranon bursitis
0.000 0.518 0.482
E23 Hypofunction and other disorders of pituitary gland
0.000 0.519 0.481
M46.46 Discitis, unspecified (Lumbar region)
0.000 0.519 0.481
H60.4 Cholesteatoma of external ear
0.000 0.519 0.481
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.520 0.479
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.520 0.479
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.520 0.479
E89.5 Postprocedural testicular hypofunction
0.000 0.520 0.479
E89.1 Postprocedural hypoinsulinaemia
0.000 0.520 0.479
I51.8 Other ill-defined heart diseases
0.000 0.521 0.479
H74.9 Disorder of middle ear and mastoid, unspecified
0.000 0.521 0.479
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.521 0.478
E45 Retarded development following protein-energy malnutrition
0.000 0.521 0.478
E43 Unspecified severe protein-energy malnutrition
0.000 0.521 0.478
E42 Marasmic kwashiorkor
0.000 0.521 0.478
E41 Nutritional marasmus
0.000 0.521 0.478
E40 Kwashiorkor
0.000 0.521 0.478
M70.3 Other bursitis of elbow
0.000 0.522 0.478
I51 Complications and ill-defined descriptions of heart disease
0.000 0.522 0.478
H61 Other disorders of external ear
0.000 0.524 0.476
H60.2 Malignant otitis externa
0.000 0.525 0.475
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.000 0.526 0.474
H68 Eustachian salpingitis and obstruction
0.000 0.526 0.474
H67 Otitis media in diseases classified elsewhere
0.000 0.526 0.474
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.526 0.474
M06.18 Adult-onset Still's disease (Other)
0.000 0.526 0.474
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.526 0.474
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.526 0.474
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.526 0.474
M06.14 Adult-onset Still's disease (Hand)
0.000 0.526 0.474
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.526 0.474
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.526 0.474
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.526 0.474
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.526 0.474
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.526 0.474
M06.28 Rheumatoid bursitis (Other)
0.000 0.526 0.474
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.526 0.474
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.526 0.474

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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