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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3134604
log Bayes Factor = 138.673
Chromosome 6   position 32,122,386  (GRCh37) Explore rs3134604 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
Chapter IX Diseases of the circulatory system
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
# Top node
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
I10-I15 Hypertensive diseases
0.000 0.000 1.000
Chapter XI Diseases of the digestive system
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
I10 Essential (primary) hypertension
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
L40-L45 Papulosquamous disorders
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
K51.9 Ulcerative colitis, unspecified
0.999 0.001 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.001 0.999
E83.1 Disorders of iron metabolism
0.999 0.001 0.000
E16 Other disorders of pancreatic internal secretion
0.000 0.001 0.999
K51 Ulcerative colitis
0.999 0.001 0.000
E16.2 Hypoglycaemia, unspecified
0.000 0.001 0.999
K90 Intestinal malabsorption
0.000 0.001 0.999
H36 Retinal disorders in diseases classified elsewhere
0.000 0.001 0.999
K90-K93 Other diseases of the digestive system
0.000 0.002 0.998
L43 Lichen planus
0.000 0.002 0.998
G35-G37 Demyelinating diseases of the central nervous system
0.998 0.002 0.000
H30-H36 Disorders of choroid and retina
0.000 0.002 0.998
Chapter VII Diseases of the eye and adnexa
0.000 0.003 0.997
E14 Unspecified diabetes mellitus
0.000 0.003 0.997
I20 Angina pectoris
0.000 0.003 0.997
L40.9 Psoriasis, unspecified
0.000 0.003 0.997
E10.4 With neurological complications
0.000 0.003 0.997
E78.0 Pure hypercholesterolaemia
0.000 0.003 0.997
L43.9 Lichen planus, unspecified
0.000 0.003 0.997
G37 Other demyelinating diseases of central nervous system
0.996 0.004 0.000
I30-I52 Other forms of heart disease
0.000 0.006 0.994
M05 Seropositive rheumatoid arthritis
0.000 0.008 0.992
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.008 0.992
G37.9 Demyelinating disease of central nervous system, unspecified
0.992 0.008 0.000
K70-K77 Diseases of liver
0.000 0.008 0.992
I47 Paroxysmal tachycardia
0.000 0.010 0.990
I25.1 Atherosclerotic heart disease
0.000 0.010 0.990
I35 Nonrheumatic aortic valve disorders
0.000 0.010 0.990
I22 Subsequent myocardial infarction
0.000 0.012 0.988
I35.0 Aortic (valve) stenosis
0.000 0.012 0.988
I20.0 Unstable angina
0.000 0.012 0.988
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.013 0.987
K51.3 Ulcerative (chronic) rectosigmoiditis
0.987 0.013 0.000
E14.3 With ophthalmic complications
0.000 0.013 0.987
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.013 0.987
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.016 0.984
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.000 0.016 0.984
E70-E90 Metabolic disorders
0.000 0.017 0.983
K74 Fibrosis and cirrhosis of liver
0.000 0.018 0.982
H43-H45 Disorders of vitreous body and globe
0.000 0.019 0.981
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.019 0.981
K82 Other diseases of gallbladder
0.000 0.020 0.980
K82.8 Other specified diseases of gallbladder
0.000 0.023 0.977
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.024 0.976
H43 Disorders of vitreous body
0.000 0.025 0.975
I47.1 Supraventricular tachycardia
0.000 0.026 0.974
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.030 0.970
E11.3 With ophthalmic complications
0.000 0.032 0.968
K74.3 Primary biliary cirrhosis
0.000 0.033 0.967
I24 Other acute ischaemic heart diseases
0.000 0.034 0.966
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.041 0.959
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.042 0.958
E10.5 With peripheral circulatory complications
0.000 0.043 0.957
I25.2 Old myocardial infarction
0.000 0.045 0.955
J45.9 Asthma, unspecified
0.000 0.045 0.955
H40-H42 Glaucoma
0.000 0.047 0.953
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.048 0.952
M07 Psoriatic and enteropathic arthropathies
0.000 0.048 0.952
I20.9 Angina pectoris, unspecified
0.000 0.048 0.952
H43.8 Other disorders of vitreous body
0.000 0.052 0.948
E14.9 Without complications
0.000 0.056 0.944
K51.2 Ulcerative (chronic) proctitis
0.943 0.057 0.000
H34 Retinal vascular occlusions
0.000 0.061 0.939
K50-K52 Noninfective enteritis and colitis
0.016 0.062 0.922
K51.8 Other ulcerative colitis
0.932 0.068 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.070 0.930
H40 Glaucoma
0.000 0.078 0.922
H40.9 Glaucoma, unspecified
0.000 0.079 0.921
H43.3 Other vitreous opacities
0.000 0.079 0.921
I25.5 Ischaemic cardiomyopathy
0.000 0.079 0.921
K72 Hepatic failure, not elsewhere classified
0.000 0.080 0.920
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.081 0.919
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.081 0.919
M07.3 Other psoriatic arthropathies
0.000 0.083 0.917
E07 Other disorders of thyroid
0.000 0.091 0.909
I21 Acute myocardial infarction
0.000 0.091 0.909
E11.2 With renal complications
0.000 0.095 0.905
E10.2 With renal complications
0.000 0.103 0.897
I47.2 Ventricular tachycardia
0.000 0.103 0.897
K81 Cholecystitis
0.000 0.105 0.895
G37.8 Other specified demyelinating diseases of central nervous system
0.895 0.105 0.000
E83 Disorders of mineral metabolism
0.858 0.107 0.036
J45 Asthma
0.000 0.108 0.892
I46 Cardiac arrest
0.000 0.111 0.889
I20.1 Angina pectoris with documented spasm
0.000 0.119 0.881
I21.9 Acute myocardial infarction, unspecified
0.000 0.119 0.881
I31 Other diseases of pericardium
0.000 0.120 0.880
J40-J47 Chronic lower respiratory diseases
0.000 0.124 0.876
Chapter X Diseases of the respiratory system
0.000 0.126 0.874
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.127 0.873
K82.1 Hydrops of gallbladder
0.000 0.127 0.873
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.133 0.867
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.136 0.864
E03.8 Other specified hypothyroidism
0.000 0.137 0.863
M70-M79 Other soft tissue disorders
0.000 0.139 0.861
E13 Other specified diabetes mellitus
0.000 0.141 0.859
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.142 0.858
E07.9 Disorder of thyroid, unspecified
0.000 0.145 0.855
K74.6 Other and unspecified cirrhosis of liver
0.000 0.145 0.855
H34.2 Other retinal artery occlusions
0.000 0.145 0.855
E11.1 With ketoacidosis
0.000 0.148 0.852
K81.1 Chronic cholecystitis
0.000 0.149 0.851
K52 Other non-infective gastro-enteritis and colitis
0.003 0.154 0.844
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.156 0.844
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.157 0.843
K75 Other inflammatory liver diseases
0.000 0.158 0.842
K72.9 Hepatic failure, unspecified
0.000 0.158 0.842
K51.5 Mucosal proctocolitis
0.832 0.168 0.000
E11.5 With peripheral circulatory complications
0.000 0.168 0.832
I46.9 Cardiac arrest, unspecified
0.000 0.169 0.831
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.170 0.830
K60 Fissure and fistula of anal and rectal regions
0.000 0.170 0.830
K55-K64 Other diseases of intestines
0.000 0.171 0.829
K60.2 Anal fissure, unspecified
0.000 0.176 0.824
J95-J99 Other diseases of the respiratory system
0.000 0.177 0.823
M06.4 Inflammatory polyarthropathy
0.000 0.177 0.823
M75 Shoulder lesions
0.000 0.180 0.820
E05.9 Thyrotoxicosis, unspecified
0.000 0.184 0.816
I31.3 Pericardial effusion (noninflammatory)
0.000 0.185 0.815
I47.0 Reentry ventricular arrhythmia
0.000 0.187 0.813
M75.0 Adhesive capsulitis of shoulder
0.000 0.190 0.810
K52.9 Non-infective gastro-enteritis and colitis, unspecified
0.000 0.190 0.810
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.192 0.808
I15 Secondary hypertension
0.000 0.193 0.807
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.194 0.806
I12 Hypertensive renal disease
0.000 0.195 0.805
E83.3 Disorders of phosphorus metabolism
0.795 0.195 0.009
E11.0 With coma
0.000 0.196 0.804
Chapter VI Diseases of the nervous system
0.800 0.199 0.002
Chapter VIII Diseases of the ear and mastoid process
0.000 0.199 0.801
I45 Other conduction disorders
0.000 0.200 0.800
K81.9 Cholecystitis, unspecified
0.000 0.203 0.797
I35.8 Other aortic valve disorders
0.000 0.204 0.796
K73 Chronic hepatitis, not elsewhere classified
0.000 0.206 0.794
H34.8 Other retinal vascular occlusions
0.000 0.207 0.793
M06.3 Rheumatoid nodule
0.000 0.207 0.793
E06 Thyroiditis
0.000 0.209 0.791
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.210 0.790
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.211 0.789
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.212 0.788
K80 Cholelithiasis
0.000 0.212 0.788
I25.4 Coronary artery aneurysm
0.000 0.214 0.786
K80.2 Calculus of gallbladder without cholecystitis
0.000 0.214 0.786
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.216 0.784
L43.8 Other lichen planus
0.000 0.217 0.783
H43.9 Disorder of vitreous body, unspecified
0.000 0.218 0.782
K74.5 Biliary cirrhosis, unspecified
0.000 0.220 0.780
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.220 0.780
M65-M68 Disorders of synovium and tendon
0.000 0.220 0.780
I25.3 Aneurysm of heart
0.000 0.220 0.780
G80-G83 Cerebral palsy and other paralytic syndromes
0.779 0.221 0.001
K50 Crohn's disease [regional enteritis]
0.001 0.222 0.777
K60.0 Acute anal fissure
0.000 0.222 0.778
J98 Other respiratory disorders
0.000 0.231 0.769
I35.2 Aortic (valve) stenosis with insufficiency
0.000 0.234 0.766
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.235 0.765
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.243 0.757
E13.9 Without complications
0.000 0.243 0.757
G81 Hemiplegia
0.755 0.244 0.000
E74 Other disorders of carbohydrate metabolism
0.000 0.245 0.755
E11.6 With other specified complications
0.000 0.247 0.753
E88 Other metabolic disorders
0.000 0.250 0.750
K72.0 Acute and subacute hepatic failure
0.000 0.252 0.748
K75.4 Autoimmune hepatitis
0.000 0.252 0.748
M70 Soft tissue disorders related to use, overuse and pressure
0.000 0.253 0.747
H30 Chorioretinal inflammation
0.000 0.255 0.745
L40.8 Other psoriasis
0.000 0.255 0.744
M11 Other crystal arthropathies
0.000 0.257 0.743
M75.2 Bicipital tendinitis
0.000 0.259 0.741
G81.9 Hemiplegia, unspecified
0.739 0.261 0.000
H60-H62 Diseases of external ear
0.000 0.264 0.736
E40-E46 Malnutrition
0.000 0.264 0.736
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.736 0.264 0.000
K90.9 Intestinal malabsorption, unspecified
0.000 0.265 0.735
I23 Certain current complications following acute myocardial infarction
0.000 0.266 0.734
J98.4 Other disorders of lung
0.000 0.268 0.732
J44 Other chronic obstructive pulmonary disease
0.000 0.269 0.731
H40.1 Primary open-angle glaucoma
0.000 0.269 0.731
L40.0 Psoriasis vulgaris
0.000 0.269 0.731
K60.5 Anorectal fistula
0.000 0.270 0.730
K82.3 Fistula of gallbladder
0.000 0.270 0.730
K55 Vascular disorders of intestine
0.000 0.270 0.730
G30-G32 Other degenerative diseases of the nervous system
0.728 0.272 0.001
J86 Pyothorax
0.000 0.272 0.728
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.274 0.726
J43 Emphysema
0.000 0.276 0.724
J46 Status asthmaticus
0.000 0.277 0.723
M06.0 Seronegative rheumatoid arthritis
0.000 0.277 0.723
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.283 0.717
E10.8 With unspecified complications
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E10.6 With other specified complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
I00-I02 Acute rheumatic fever
0.000 0.283 0.717
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.3 Pustulosis palmaris et plantaris
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
I13 Hypertensive heart and renal disease
0.000 0.283 0.717
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
L44 Other papulosquamous disorders
0.000 0.283 0.717
L41 Parapsoriasis
0.000 0.283 0.717
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.716
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.284 0.716
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.284 0.716
E16.4 Abnormal secretion of gastrin
0.000 0.284 0.716
E16.3 Increased secretion of glucagon
0.000 0.284 0.716
E16.1 Other hypoglycaemia
0.000 0.284 0.716
K90.3 Pancreatic steatorrhoea
0.000 0.284 0.716
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.284 0.716
K90.1 Tropical sprue
0.000 0.284 0.716
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.284 0.716
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.284 0.716
L43.3 Subacute (active) lichen planus
0.000 0.284 0.716
L43.2 Lichenoid drug reaction
0.000 0.284 0.716
L43.1 Bullous lichen planus
0.000 0.284 0.716
L43.0 Hypertrophic lichen planus
0.000 0.284 0.716
G36 Other acute disseminated demyelination
0.715 0.284 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.285 0.715
E14.8 With unspecified complications
0.000 0.285 0.715
E14.7 With multiple complications
0.000 0.285 0.715
E14.6 With other specified complications
0.000 0.285 0.715
E14.5 With peripheral circulatory complications
0.000 0.285 0.715
E14.4 With neurological complications
0.000 0.285 0.715
E14.2 Withrenal complications
0.000 0.285 0.715
E14.1 With ketoacidosis
0.000 0.285 0.715
E14.0 With coma
0.000 0.285 0.715
K51.1 Ulcerative (chronic) ileocolitis
0.714 0.285 0.000
G37.5 Concentric sclerosis [Balo]
0.714 0.286 0.000
G37.4 Subacute necrotising myelitis
0.714 0.286 0.000
G37.2 Central pontine myelinolysis
0.714 0.286 0.000
G37.1 Central demyelination of corpus callosum
0.714 0.286 0.000
G37.0 Diffuse sclerosis
0.714 0.286 0.000
H65-H75 Diseases of middle ear and mastoid
0.000 0.286 0.714
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.287 0.713
I52 Other heart disorders in diseases classified elsewhere
0.000 0.287 0.713
I48 Atrial fibrillation and flutter
0.000 0.287 0.713
I41 Myocarditis in diseases classified elsewhere
0.000 0.287 0.713
I40 Acute myocarditis
0.000 0.287 0.713
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.287 0.713
I32 Pericarditis in diseases classified elsewhere
0.000 0.287 0.713
M14 Arthropathies in other diseases classified elsewhere
0.000 0.288 0.712
K51.4 Pseudopolyposis of colon
0.712 0.288 0.000
M05.8 Other seropositive rheumatoid arthritis
0.000 0.288 0.711
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.288 0.711
M05.2 Rheumatoid vasculitis
0.000 0.288 0.711
M05.1 Rheumatoid lung disease
0.000 0.288 0.711
M05.0 Felty's syndrome
0.000 0.288 0.711
E83.9 Disorder of mineral metabolism, unspecified
0.689 0.289 0.022
K77 Liver disorders in diseases classified elsewhere
0.000 0.289 0.711
K71 Toxic liver disease
0.000 0.289 0.711
K52.1 Toxic gastro-enteritis and colitis
0.001 0.291 0.708
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.292 0.708
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.292 0.708
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.292 0.708
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.292 0.708
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.292 0.708
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.292 0.708
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.292 0.708
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.292 0.708
I12.9 Hypertensive renal disease without renal failure
0.000 0.292 0.708
M77 Other enthesopathies
0.000 0.293 0.707
E78.6 Lipoprotein deficiency
0.000 0.294 0.705
E78.3 Hyperchylomicronaemia
0.000 0.294 0.705
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.000 0.295 0.705
E84 Cystic fibrosis
0.000 0.295 0.705
E77 Disorders of glycoprotein metabolism
0.000 0.295 0.705
E76 Disorders of glycosaminoglycan metabolism
0.000 0.295 0.705
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.295 0.705
E72 Other disorders of amino-acid metabolism
0.000 0.295 0.705
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.295 0.705
E70 Disorders of aromatic amino-acid metabolism
0.000 0.295 0.705
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.295 0.705
E83.5 Disorders of calcium metabolism
0.701 0.296 0.003
K74.4 Secondary biliary cirrhosis
0.000 0.296 0.704
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.296 0.704
K74.1 Hepatic sclerosis
0.000 0.296 0.704
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.000 0.296 0.703
I11 Hypertensive heart disease
0.000 0.298 0.702
M65 Synovitis and tenosynovitis
0.000 0.299 0.701
I45.2 Bifascicular block
0.000 0.300 0.700
K82.9 Disease of gallbladder, unspecified
0.000 0.300 0.700
H43.2 Crystalline deposits in vitreous body
0.000 0.301 0.699
H43.0 Vitreous prolapse
0.000 0.301 0.699
H34.1 Central retinal artery occlusion
0.000 0.302 0.698
I30 Acute pericarditis
0.000 0.305 0.695
K82.2 Perforation of gallbladder
0.000 0.305 0.695
M70.4 Prepatellar bursitis
0.000 0.308 0.692
K51.0 Ulcerative (chronic) enterocolitis
0.692 0.308 0.000
G83 Other paralytic syndromes
0.686 0.313 0.000
E78.2 Mixed hyperlipidaemia
0.000 0.313 0.686
H71 Cholesteatoma of middle ear
0.000 0.314 0.686
I45.5 Other specified heart block
0.000 0.315 0.685
M75.3 Calcific tendinitis of shoulder
0.000 0.316 0.684
E79 Disorders of purine and pyrimidine metabolism
0.000 0.316 0.684
H42 Glaucoma in diseases classified elsewhere
0.000 0.316 0.683
M07.6 Other enteropathic arthropathies
0.000 0.318 0.682
M07.5 Arthropathy in ulcerative colitis
0.000 0.318 0.682
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.318 0.682
M07.2 Psoriatic spondylitis
0.000 0.318 0.682
M07.1 Arthritis mutilans
0.000 0.318 0.682
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.318 0.682
E78.1 Pure hyperglyceridaemia
0.000 0.318 0.682
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.002 0.320 0.678
E11.8 With unspecified complications
0.000 0.321 0.679
K55.2 Angiodysplasia of colon
0.000 0.322 0.677
I44 Atrioventricular and left bundle-branch block
0.000 0.323 0.677
K50.8 Other Crohn's disease
0.000 0.323 0.676
H34.9 Retinal vascular occlusion, unspecified
0.000 0.326 0.673
H34.0 Transient retinal artery occlusion
0.000 0.326 0.673
E06.3 Autoimmune thyroiditis
0.000 0.327 0.673
G30 Alzheimer's disease
0.671 0.329 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.000 0.329 0.671
L42 Pityriasis rosea
0.000 0.330 0.670
E11.4 With neurological complications
0.000 0.330 0.670
I51 Complications and ill-defined descriptions of heart disease
0.000 0.330 0.670
M65.4 Radial styloid tenosynovitis [de Quervain]
0.000 0.330 0.670
E78.8 Other disorders of lipoprotein metabolism
0.000 0.336 0.664
E78.4 Other hyperlipidaemia
0.000 0.336 0.664
I37 Pulmonary valve disorders
0.000 0.338 0.662
J98.0 Diseases of bronchus, not elsewhere classified
0.000 0.339 0.661
H40.6 Glaucoma secondary to drugs
0.000 0.339 0.661
H40.4 Glaucoma secondary to eye inflammation
0.000 0.339 0.661
H40.3 Glaucoma secondary to eye trauma
0.000 0.339 0.661
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.339 0.660
K72.1 Chronic hepatic failure
0.000 0.340 0.659
K90.8 Other intestinal malabsorption
0.000 0.340 0.659
I36 Nonrheumatic tricuspid valve disorders
0.000 0.341 0.659
H61 Other disorders of external ear
0.000 0.341 0.659
M07.38 Other psoriatic arthropathies (Other)
0.000 0.342 0.658
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.342 0.658
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.342 0.658
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.342 0.658
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.342 0.658
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.342 0.658
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.342 0.658
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.342 0.658
K82.0 Obstruction of gallbladder
0.000 0.343 0.657
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.345 0.655
M12 Other specific arthropathies
0.000 0.347 0.653
M70.46 Prepatellar bursitis-Lower Leg
0.000 0.347 0.653
E07.1 Dyshormogenetic goitre
0.000 0.348 0.652
E07.0 Hypersecretion of calcitonin
0.000 0.348 0.652
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.348 0.652
M77.1 Lateral epicondylitis
0.000 0.348 0.652
I15.1 Hypertension secondary to other renal disorders
0.000 0.349 0.651
H43.1 Vitreous haemorrhage
0.000 0.352 0.648
J86.9 Pyothorax without fistula
0.000 0.353 0.646
M06.34 Rheumatoid nodule (Hand)
0.000 0.355 0.645
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.355 0.645
K58 Irritable bowel syndrome
0.000 0.357 0.643
E83.8 Other disorders of mineral metabolism
0.615 0.359 0.026
E83.2 Disorders of zinc metabolism
0.615 0.359 0.026
E83.0 Disorders of copper metabolism
0.615 0.359 0.026
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.359 0.640
J45.8 Mixed asthma
0.000 0.360 0.640
J45.1 Nonallergic asthma
0.000 0.360 0.640
M45-M49 Spondylopathies
0.000 0.360 0.640
I05-I09 Chronic rheumatic heart diseases
0.000 0.362 0.638
I46.1 Sudden cardiac death, so described
0.000 0.362 0.638
K55.8 Other vascular disorders of intestine
0.000 0.366 0.634
I45.8 Other specified conduction disorders
0.000 0.369 0.631
I31.8 Other specified diseases of pericardium
0.000 0.369 0.631
I31.2 Haemopericardium, not elsewhere classified
0.000 0.369 0.631
I31.0 Chronic adhesive pericarditis
0.000 0.369 0.631
J98.6 Disorders of diaphragm
0.000 0.370 0.630
I31.9 Disease of pericardium, unspecified
0.000 0.370 0.630
I45.1 Other and unspecified right bundle-branch block
0.000 0.370 0.630
J41 Simple and mucopurulent chronic bronchitis
0.000 0.372 0.628
H66 Suppurative and unspecified otitis media
0.000 0.373 0.627
J86.0 Pyothorax with fistula
0.000 0.375 0.625
M86-M90 Other osteopathies
0.000 0.375 0.625
I51.8 Other ill-defined heart diseases
0.000 0.378 0.622
K50.9 Crohn's disease, unspecified
0.000 0.379 0.621
E73 Lactose intolerance
0.000 0.379 0.621
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.379 0.621
M45 Ankylosing spondylitis
0.000 0.380 0.620
E05.5 Thyroid crisis or storm
0.000 0.380 0.619
E05.4 Thyrotoxicosis factitia
0.000 0.380 0.619
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.380 0.619
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.380 0.619
I24.1 Dressler's syndrome
0.000 0.381 0.619
K80.8 Other cholelithiasis
0.000 0.381 0.619
G30.9 Alzheimer's disease, unspecified
0.618 0.382 0.000
I22.8 Subsequent myocardial infarction of other sites
0.000 0.382 0.617
M73 Soft tissue disorders in diseases classified elsewhere
0.000 0.383 0.617
H66.3 Other chronic suppurative otitis media
0.000 0.383 0.617
K73.9 Chronic hepatitis, unspecified
0.000 0.384 0.616
E13.8 With unspecified complications
0.000 0.384 0.615
E13.7 With multiple complications
0.000 0.384 0.615
E13.6 With other specified complications
0.000 0.384 0.615
E13.5 With peripheral circulatory complications
0.000 0.384 0.615
E13.4 With neurological complications
0.000 0.384 0.615
E13.3 With ophthalmic complications
0.000 0.384 0.615
E13.2 With renal complications
0.000 0.384 0.615
E13.1 With ketoacidosis
0.000 0.384 0.615
E13.0 With coma
0.000 0.384 0.615
I21.4 Acute subendocardial myocardial infarction
0.000 0.385 0.615
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.385 0.615
K75.8 Other specified inflammatory liver diseases
0.000 0.386 0.614
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.000 0.387 0.613
H60 Otitis externa
0.000 0.387 0.613
M77.12 Lateral epicondylitis (Upper arm)
0.000 0.388 0.612
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.390 0.610
J43.2 Centrilobular emphysema
0.000 0.394 0.606
K75.0 Abscess of liver
0.000 0.394 0.606
I15.9 Seconday hypertension, unspecified
0.000 0.395 0.605
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.396 0.604
K75.2 Nonspecific reactive hepatitis
0.000 0.396 0.604
K75.1 Phlebitis of portal vein
0.000 0.396 0.604
E07.8 Other specified disorders of thyroid
0.000 0.399 0.601
K81.8 Other cholecystitis
0.000 0.400 0.600
K63 Other diseases of intestine
0.000 0.402 0.598
L10-L14 Bullous disorders
0.000 0.403 0.596
G40-G47 Episodic and paroxysmal disorders
0.596 0.404 0.000
E89.3 Postprocedural hypopituitarism
0.000 0.404 0.595
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.405 0.595
K64 Haemorrhoids and perianal venous thrombosis
0.000 0.406 0.594
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.000 0.406 0.594
H40.5 Glaucoma secondary to other eye disorders
0.000 0.407 0.593
I44.3 Other and unspecified atrioventricular block
0.000 0.407 0.593
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.408 0.592
I24.8 Other forms of acute ischaemic heart disease
0.000 0.408 0.592
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.409 0.591
K60.4 Rectal fistula
0.000 0.409 0.591
J98.5 Diseases of mediastinum, not elsewhere classified
0.000 0.410 0.590
J96 Respiratory failure, not elsewhere classified
0.000 0.410 0.590
G00-G09 Inflammatory diseases of the central nervous system
0.589 0.410 0.001
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.410 0.590
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.410 0.590
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.410 0.590
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.410 0.590
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.410 0.590
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.410 0.590
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.410 0.590
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.410 0.590
E89.2 Postprocedural hypoparathyroidism
0.000 0.411 0.589
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.412 0.588
M75.8 Other shoulder lesions
0.000 0.412 0.588
K52.3 Indeterminate colitis
0.002 0.413 0.585
G83.4 Cauda equina syndrome
0.586 0.414 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.000 0.415 0.585
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.584 0.415 0.001
H61.1 Non-infective disorders of pinna
0.000 0.416 0.584
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.002 0.417 0.581
K50.0 Crohn's disease of small intestine
0.000 0.419 0.580
I44.7 Left bundle-branch block, unspecified
0.000 0.421 0.579
I15.8 Other secondary hypertension
0.000 0.421 0.579
I15.2 Hypertension secondary to endocrine disorders
0.000 0.421 0.579
I15.0 Renovascular hypertension
0.000 0.421 0.579
K58.0 Irritable bowel syndrome with diarrhoea
0.000 0.421 0.579
H61.0 Perichondritis of external ear
0.000 0.425 0.575
I45.0 Right fascicular block
0.000 0.426 0.574
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.426 0.573
H31 Other disorders of choroid
0.000 0.427 0.572

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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