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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3134899
log Bayes Factor = 68.5162
Chromosome 6   position 31,473,286  (GRCh37) Explore rs3134899 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
I25.1 Atherosclerotic heart disease
0.000 0.001 0.999
J45.9 Asthma, unspecified
0.000 0.002 0.998
I24 Other acute ischaemic heart diseases
0.000 0.003 0.997
L40.5 Arthropathic psoriasis
0.000 0.004 0.996
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.004 0.996
E14.3 With ophthalmic complications
0.000 0.007 0.993
M45 Ankylosing spondylitis
0.000 0.007 0.993
G35-G37 Demyelinating diseases of the central nervous system
0.992 0.008 0.000
E83.1 Disorders of iron metabolism
0.992 0.008 0.000
I20 Angina pectoris
0.000 0.009 0.991
G37 Other demyelinating diseases of central nervous system
0.991 0.009 0.000
I20.9 Angina pectoris, unspecified
0.000 0.010 0.990
E14.9 Without complications
0.000 0.011 0.989
I10-I15 Hypertensive diseases
0.000 0.011 0.989
I10 Essential (primary) hypertension
0.000 0.011 0.989
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.011 0.989
L40-L45 Papulosquamous disorders
0.000 0.011 0.989
E78.0 Pure hypercholesterolaemia
0.000 0.012 0.988
G37.9 Demyelinating disease of central nervous system, unspecified
0.987 0.013 0.000
I25.2 Old myocardial infarction
0.000 0.017 0.983
Chapter IX Diseases of the circulatory system
0.000 0.019 0.981
H65-H75 Diseases of middle ear and mastoid
0.000 0.021 0.979
E10.1 With ketoacidosis
0.000 0.021 0.979
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.021 0.979
E10.4 With neurological complications
0.000 0.025 0.975
H71 Cholesteatoma of middle ear
0.000 0.026 0.974
I25.5 Ischaemic cardiomyopathy
0.000 0.027 0.973
E70-E90 Metabolic disorders
0.000 0.028 0.972
Chapter VIII Diseases of the ear and mastoid process
0.000 0.029 0.971
I22 Subsequent myocardial infarction
0.000 0.030 0.970
H66 Suppurative and unspecified otitis media
0.000 0.031 0.969
H66.3 Other chronic suppurative otitis media
0.000 0.032 0.968
# Top node
0.000 0.036 0.964
I24.8 Other forms of acute ischaemic heart disease
0.000 0.041 0.959
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.044 0.956
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.054 0.946
M75.0 Adhesive capsulitis of shoulder
0.000 0.054 0.946
M75 Shoulder lesions
0.000 0.055 0.945
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.056 0.944
M45-M49 Spondylopathies
0.000 0.056 0.944
M70-M79 Other soft tissue disorders
0.000 0.058 0.942
I12 Hypertensive renal disease
0.000 0.060 0.940
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.060 0.940
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.060 0.940
L43 Lichen planus
0.000 0.061 0.939
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.064 0.936
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.072 0.928
M75.4 Impingement syndrome of shoulder
0.000 0.077 0.923
E16 Other disorders of pancreatic internal secretion
0.000 0.085 0.915
H73 Other disorders of tympanic membrane
0.000 0.094 0.906
G37.8 Other specified demyelinating diseases of central nervous system
0.899 0.101 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.103 0.897
I12.9 Hypertensive renal disease without renal failure
0.000 0.103 0.897
H74 Other disorders of middle ear and mastoid
0.000 0.108 0.892
I15 Secondary hypertension
0.000 0.108 0.892
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.109 0.891
E13 Other specified diabetes mellitus
0.000 0.113 0.887
L43.9 Lichen planus, unspecified
0.000 0.114 0.886
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.119 0.881
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.121 0.879
H60-H62 Diseases of external ear
0.000 0.126 0.874
E16.2 Hypoglycaemia, unspecified
0.000 0.127 0.873
E11.1 With ketoacidosis
0.000 0.145 0.855
L40.8 Other psoriasis
0.000 0.146 0.854
E78.2 Mixed hyperlipidaemia
0.000 0.152 0.848
H73.8 Other specified disorders of tympanic membrane
0.000 0.162 0.838
M70 Soft tissue disorders related to use, overuse and pressure
0.000 0.163 0.837
E78.8 Other disorders of lipoprotein metabolism
0.000 0.165 0.835
M79 Other soft tissue disorders, not elsewhere classified
0.000 0.172 0.828
E11.0 With coma
0.000 0.173 0.827
I25.3 Aneurysm of heart
0.000 0.182 0.818
I23 Certain current complications following acute myocardial infarction
0.000 0.190 0.810
M79.6 Pain in limb
0.000 0.191 0.809
E10.0 With coma
0.000 0.191 0.809
E13.9 Without complications
0.000 0.193 0.807
E11.2 With renal complications
0.000 0.195 0.805
E10.5 With peripheral circulatory complications
0.000 0.195 0.805
M75.2 Bicipital tendinitis
0.000 0.198 0.802
E85 Amyloidosis
0.000 0.198 0.802
M79.65 Pain in limb (Pelvic region and thigh)
0.000 0.203 0.797
E14.1 With ketoacidosis
0.000 0.204 0.796
E14.8 With unspecified complications
0.000 0.210 0.790
I15.1 Hypertension secondary to other renal disorders
0.000 0.217 0.783
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.783 0.217 0.000
E11.6 With other specified complications
0.000 0.218 0.782
H74.8 Other specified disorders of middle ear and mastoid
0.000 0.225 0.775
E14.6 With other specified complications
0.000 0.226 0.774
H74.9 Disorder of middle ear and mastoid, unspecified
0.000 0.228 0.772
H74.4 Polyp of middle ear
0.000 0.229 0.771
H73.9 Disorder of tympanic membrane, unspecified
0.000 0.232 0.768
E10.8 With unspecified complications
0.000 0.232 0.768
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.235 0.765
H60 Otitis externa
0.000 0.242 0.758
L43.8 Other lichen planus
0.000 0.242 0.758
H90-H95 Other disorders of ear
0.000 0.246 0.754
E10.2 With renal complications
0.000 0.248 0.752
M70.6 Trochanteric bursitis
0.000 0.256 0.744
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.257 0.743
M79.60 Pain in limb (Multiple sites)
0.000 0.257 0.743
E78.1 Pure hyperglyceridaemia
0.000 0.257 0.743
E11.3 With ophthalmic complications
0.000 0.258 0.742
E83 Disorders of mineral metabolism
0.689 0.260 0.050
I20.0 Unstable angina
0.000 0.265 0.735
E74 Other disorders of carbohydrate metabolism
0.000 0.266 0.734
E78.6 Lipoprotein deficiency
0.000 0.266 0.734
I12.0 Hypertensive renal disease with renal failure
0.000 0.272 0.728
H61 Other disorders of external ear
0.000 0.273 0.727
I15.9 Seconday hypertension, unspecified
0.000 0.273 0.727
H30-H36 Disorders of choroid and retina
0.000 0.278 0.722
H36.0 Diabetic retinopathy
0.000 0.279 0.721
H36 Retinal disorders in diseases classified elsewhere
0.000 0.279 0.721
E14.4 With neurological complications
0.000 0.280 0.720
E10.6 With other specified complications
0.000 0.281 0.719
H35 Other retinal disorders
0.000 0.281 0.719
H66.1 Chronic tubotympanic suppurative otitis media
0.000 0.282 0.718
H66.4 Suppurative otitis media, unspecified
0.000 0.282 0.718
E10.7 With multiple complications
0.000 0.283 0.717
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.2 Withrenal complications
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.3 Pustulosis palmaris et plantaris
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.283 0.717
M79.63 Pain in limb (Forearm)
0.000 0.284 0.716
E14.5 With peripheral circulatory complications
0.000 0.284 0.715
M70.4 Prepatellar bursitis
0.000 0.285 0.715
Chapter VII Diseases of the eye and adnexa
0.000 0.287 0.713
G36 Other acute disseminated demyelination
0.712 0.288 0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.288 0.712
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.288 0.712
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.288 0.712
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.288 0.712
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.288 0.712
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.288 0.712
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.288 0.712
G37.5 Concentric sclerosis [Balo]
0.710 0.289 0.000
G37.4 Subacute necrotising myelitis
0.710 0.289 0.000
G37.2 Central pontine myelinolysis
0.710 0.289 0.000
G37.1 Central demyelination of corpus callosum
0.710 0.289 0.000
G37.0 Diffuse sclerosis
0.710 0.289 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.290 0.710
I13 Hypertensive heart and renal disease
0.000 0.291 0.709
L44 Other papulosquamous disorders
0.000 0.291 0.709
L41 Parapsoriasis
0.000 0.291 0.709
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.291 0.709
L42 Pityriasis rosea
0.000 0.293 0.707
I11 Hypertensive heart disease
0.000 0.293 0.707
M79.62 Pain in limb (Upper arm)
0.000 0.296 0.704
I00-I02 Acute rheumatic fever
0.000 0.296 0.703
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.000 0.298 0.702
H68 Eustachian salpingitis and obstruction
0.000 0.298 0.702
H67 Otitis media in diseases classified elsewhere
0.000 0.298 0.702
E78.3 Hyperchylomicronaemia
0.000 0.298 0.702
M86-M90 Other osteopathies
0.000 0.299 0.701
H35.8 Other specified retinal disorders
0.000 0.300 0.700
E77 Disorders of glycoprotein metabolism
0.000 0.303 0.697
E76 Disorders of glycosaminoglycan metabolism
0.000 0.303 0.697
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.303 0.697
E70 Disorders of aromatic amino-acid metabolism
0.000 0.303 0.697
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.303 0.697
H66.0 Acute suppurative otitis media
0.000 0.306 0.694
M46 Other inflammatory spondylopathies
0.000 0.307 0.693
E11.4 With neurological complications
0.000 0.308 0.692
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.309 0.691
M70.65 Trochanteric bursitis-Pelvic/Thigh
0.000 0.311 0.689
M79.7 Fibromyalgia
0.000 0.312 0.688
E16.1 Other hypoglycaemia
0.000 0.316 0.684
H90 Conductive and sensorineural hearing loss
0.000 0.317 0.683
M88 Paget's disease of bone [osteitis deformans]
0.000 0.317 0.683
H74.2 Discontinuity and dislocation of ear ossicles
0.000 0.319 0.681
E15 Nondiabetic hypoglycaemic coma
0.000 0.322 0.678
E85.9 Amyloidosis, unspecified
0.000 0.322 0.678
M49 Spondylopathies in diseases classified elsewhere
0.000 0.322 0.678
M75.8 Other shoulder lesions
0.000 0.322 0.678
M73 Soft tissue disorders in diseases classified elsewhere
0.000 0.324 0.675
I23.8 Other current complications following acute myocardial infarction
0.000 0.327 0.673
L43.3 Subacute (active) lichen planus
0.000 0.327 0.673
L43.2 Lichenoid drug reaction
0.000 0.327 0.673
L43.1 Bullous lichen planus
0.000 0.327 0.673
L43.0 Hypertrophic lichen planus
0.000 0.327 0.673
H60.3 Other infective otitis externa
0.000 0.330 0.670
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.330 0.669
M88.9 Paget's disease of bone, unspecified
0.000 0.330 0.670
E83.3 Disorders of phosphorus metabolism
0.659 0.333 0.009
E79 Disorders of purine and pyrimidine metabolism
0.000 0.334 0.666
H70 Mastoiditis and related conditions
0.000 0.339 0.660
L10-L14 Bullous disorders
0.000 0.340 0.660
H61.1 Non-infective disorders of pinna
0.000 0.341 0.659
M88.90 Paget's disease of bone, unspecified (Multiple sites)
0.000 0.341 0.659
E72 Other disorders of amino-acid metabolism
0.000 0.343 0.657
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.344 0.656
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.344 0.656
E16.4 Abnormal secretion of gastrin
0.000 0.344 0.656
E16.3 Increased secretion of glucagon
0.000 0.344 0.656
E89.3 Postprocedural hypopituitarism
0.000 0.346 0.654
H73.0 Acute myringitis
0.000 0.351 0.649
M75.3 Calcific tendinitis of shoulder
0.000 0.352 0.648
H46-H48 Disorders of optic nerve and visual pathways
0.000 0.353 0.647
M76 Enthesopathies of lower limb, excluding foot
0.000 0.354 0.646
I15.0 Renovascular hypertension
0.000 0.354 0.646
L50-L54 Urticaria and erythema
0.000 0.357 0.643
E84 Cystic fibrosis
0.000 0.358 0.641
I22.8 Subsequent myocardial infarction of other sites
0.000 0.360 0.640
I15.8 Other secondary hypertension
0.000 0.360 0.640
I15.2 Hypertension secondary to endocrine disorders
0.000 0.360 0.640
M79.1 Myalgia
0.000 0.361 0.639
H35.5 Hereditary retinal dystrophy
0.000 0.361 0.639
H90.2 Conductive hearing loss, unspecified
0.000 0.361 0.639
E13.8 With unspecified complications
0.000 0.364 0.636
E13.7 With multiple complications
0.000 0.364 0.636
E13.6 With other specified complications
0.000 0.364 0.636
E13.5 With peripheral circulatory complications
0.000 0.364 0.636
E13.4 With neurological complications
0.000 0.364 0.636
E13.3 With ophthalmic complications
0.000 0.364 0.636
E13.2 With renal complications
0.000 0.364 0.636
E13.1 With ketoacidosis
0.000 0.364 0.636
E13.0 With coma
0.000 0.364 0.636
E78.5 Hyperlipidaemia, unspecified
0.000 0.366 0.634
H35.2 Other proliferative retinopathy
0.000 0.369 0.631
M70.46 Prepatellar bursitis-Lower Leg
0.000 0.372 0.628
H60.5 Acute otitis externa, non-infective
0.000 0.374 0.625
I24.1 Dressler's syndrome
0.000 0.375 0.624
L40.0 Psoriasis vulgaris
0.000 0.376 0.624
H62 Disorders of external ear in diseases classified elsewhere
0.000 0.376 0.623
E65-E68 Obesity and other hyperalimentation
0.000 0.377 0.622
M70.2 Olecranon bursitis
0.000 0.379 0.621
E88 Other metabolic disorders
0.000 0.380 0.620
H35.7 Separation of retinal layers
0.000 0.387 0.613
M71 Other bursopathies
0.000 0.388 0.612
H47 Other disorders of optic [2nd] nerve and visual pathways
0.000 0.392 0.607
M46.9 Inflammatory spondylopathy, unspecified
0.000 0.395 0.605
H61.9 Disorder of external ear, unspecified
0.000 0.398 0.602
E85.3 Secondary systemic amyloidosis
0.000 0.400 0.600
M70.9 Unspecified soft tissue disorder related to use, overuse and pressure
0.000 0.400 0.600
M70.8 Other soft tissue disorders related to use, overuse and pressure
0.000 0.400 0.600
M70.1 Bursitis of hand
0.000 0.400 0.600
M70.0 Chronic crepitant synovitis of hand and wrist
0.000 0.400 0.600
M91-M94 Chondropathies
0.000 0.401 0.599
H92 Otalgia and effusion of ear
0.000 0.401 0.599
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.405 0.595
M79.79 Fibromyalgia (Site unspecified)
0.000 0.406 0.594
M79.3 Panniculitis, unspecified
0.000 0.406 0.593
K90 Intestinal malabsorption
0.000 0.408 0.592
H35.6 Retinal haemorrhage
0.000 0.409 0.591
H66.2 Chronic atticoantral suppurative otitis media
0.000 0.416 0.584
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.419 0.580
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.419 0.580
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.419 0.580
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.419 0.580
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.419 0.580
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.419 0.580
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.419 0.580
I25.4 Coronary artery aneurysm
0.000 0.422 0.578
M79.9 Soft tissue disorder, unspecified
0.000 0.423 0.577
H60.8 Other otitis externa
0.000 0.425 0.575
H61.3 Acquired stenosis of external ear canal
0.000 0.425 0.575
E85.8 Other amyloidosis
0.000 0.425 0.575
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.425 0.575
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.425 0.575
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.425 0.575
J45 Asthma
0.000 0.429 0.571
M79.2 Neuralgia and neuritis, unspecified
0.000 0.430 0.570
M00-M03 Infectious arthropathies
0.000 0.430 0.570
E73 Lactose intolerance
0.000 0.430 0.569
H35.4 Peripheral retinal degeneration
0.000 0.433 0.567
E11.5 With peripheral circulatory complications
0.000 0.434 0.566
H74.3 Other acquired abnormalities of ear ossicles
0.000 0.434 0.565
M79.67 Pain in limb (Ankle and foot)
0.000 0.436 0.564
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.436 0.564
M70.5 Other bursitis of knee
0.000 0.437 0.563
E40-E46 Malnutrition
0.000 0.439 0.561
M79.4 Hypertrophy of (infrapatellar) fat pad
0.000 0.440 0.560
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.000 0.441 0.559
I20.1 Angina pectoris with documented spasm
0.000 0.441 0.559
M70.3 Other bursitis of elbow
0.000 0.442 0.558
H72 Perforation of tympanic membrane
0.000 0.442 0.558
H47.3 Other disorders of optic disk
0.000 0.444 0.556
I21 Acute myocardial infarction
0.000 0.445 0.555
H90.5 Sensorineural hearing loss, unspecified
0.000 0.450 0.550
E85.4 Organ-limited amyloidosis
0.000 0.451 0.549
H60.2 Malignant otitis externa
0.000 0.456 0.543
H60.9 Otitis externa, unspecified
0.000 0.456 0.543
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.458 0.542
H94 Other disorders of ear in diseases classified elsewhere
0.000 0.459 0.541
M70.7 Other bursitis of hip
0.000 0.463 0.537
H74.0 Tympanosclerosis
0.000 0.463 0.537
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
0.000 0.464 0.536
M75.5 Bursitis of shoulder
0.000 0.464 0.536
H73.1 Chronic myringitis
0.000 0.465 0.535
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)
0.000 0.465 0.535
M70.68 Trochanteric bursitis-Other
0.000 0.467 0.533
M70.67 Trochanteric bursitis-Ankle/Foot
0.000 0.467 0.533
M70.66 Trochanteric bursitis-Lower Leg
0.000 0.467 0.533
M70.64 Trochanteric bursitis-Hand
0.000 0.467 0.533
M70.63 Trochanteric bursitis-Forearm
0.000 0.467 0.533
M70.62 Trochanteric bursitis-Upper arm
0.000 0.467 0.533
M70.61 Trochanteric bursitis-Shldr region
0.000 0.467 0.533
M70.60 Trochanteric bursitis-Mult sites
0.000 0.467 0.533
E83.9 Disorder of mineral metabolism, unspecified
0.494 0.469 0.036
E83.8 Other disorders of mineral metabolism
0.494 0.469 0.036
E83.2 Disorders of zinc metabolism
0.494 0.469 0.036
E83.0 Disorders of copper metabolism
0.494 0.469 0.036
H60.4 Cholesteatoma of external ear
0.000 0.470 0.530
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.000 0.471 0.529
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.473 0.526
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.473 0.526
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.473 0.526
E74.2 Disorders of galactose metabolism
0.000 0.473 0.526
E74.1 Disorders of fructose metabolism
0.000 0.473 0.526
E74.0 Glycogen storage disease
0.000 0.473 0.526
E88.2 Lipomatosis, not elsewhere classified
0.000 0.474 0.526
M79.16 Myalgia (Lower leg)
0.000 0.477 0.523
H47.2 Optic atrophy
0.000 0.480 0.520
H53-H54 Visual disturbances and blindness
0.000 0.481 0.519
M79.19 Myalgia (Site unspecified)
0.000 0.481 0.519
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.482 0.518
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.483 0.517
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)
0.000 0.484 0.516
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)
0.000 0.484 0.516
H35.1 Retinopathy of prematurity
0.000 0.485 0.515
L13 Other bullous disorders
0.000 0.485 0.515
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
H74.1 Adhesive middle ear disease
0.000 0.486 0.514
M70.49 Prepatellar bursitis-Site unspec
0.000 0.487 0.513
M70.48 Prepatellar bursitis-Other
0.000 0.487 0.513
M70.47 Prepatellar bursitis-Ankle/Foot
0.000 0.487 0.513
M70.45 Prepatellar bursitis-Pelvic/Thigh
0.000 0.487 0.513
M70.44 Prepatellar bursitis-Hand
0.000 0.487 0.513
M70.43 Prepatellar bursitis-Forearm
0.000 0.487 0.513
M70.42 Prepatellar bursitis-Upper arm
0.000 0.487 0.513
M70.41 Prepatellar bursitis-Shldr region
0.000 0.487 0.513
M70.40 Prepatellar bursitis-Mult sites
0.000 0.487 0.513
L52 Erythema nodosum
0.000 0.489 0.511
H90.0 Conductive hearing loss, bilateral
0.000 0.489 0.511
G36.0 Neuromyelitis optica [Devic]
0.511 0.489 0.000
G36.9 Acute disseminated demyelination, unspecified
0.510 0.489 0.000
G36.8 Other specified acute disseminated demyelination
0.510 0.489 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.510 0.489 0.000
M88.99 Paget's disease of bone, unspecified (Site unspecified)
0.000 0.490 0.510
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.491 0.509
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.491 0.509
E89.5 Postprocedural testicular hypofunction
0.000 0.491 0.509
E89.1 Postprocedural hypoinsulinaemia
0.000 0.491 0.509
M79.11 Myalgia (Shoulder region)
0.000 0.491 0.509
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.491 0.508
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.491 0.508
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.491 0.508
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.491 0.508
L41.9 Parapsoriasis, unspecified
0.000 0.492 0.508
L41.8 Other parapsoriasis
0.000 0.492 0.508
L41.5 Retiform parapsoriasis
0.000 0.492 0.508
L41.4 Large plaque parapsoriasis
0.000 0.492 0.508
L41.3 Small plaque parapsoriasis
0.000 0.492 0.508
L41.2 Lymphomatoid papulosis
0.000 0.492 0.508
L41.1 Pityriasis lichenoides chronica
0.000 0.492 0.508
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.492 0.508
L44.9 Papulosquamous disorder, unspecified
0.000 0.492 0.508
L44.8 Other specified papulosquamous disorders
0.000 0.492 0.508
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.492 0.508
L44.3 Lichen ruber moniliformis
0.000 0.492 0.508
L44.2 Lichen striatus
0.000 0.492 0.508
L44.1 Lichen nitidus
0.000 0.492 0.508
L44.0 Pityriasis rubra pilaris
0.000 0.492 0.508
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.000 0.492 0.508
H60.0 Abscess of external ear
0.000 0.492 0.508
M75.9 Shoulder lesion, unspecified
0.000 0.493 0.506
E78.4 Other hyperlipidaemia
0.000 0.495 0.505
I02 Rheumatic chorea
0.000 0.495 0.504
I01 Rheumatic fever with heart involvement
0.000 0.495 0.504
I00 Rheumatic fever without mention of heart involvement
0.000 0.495 0.504
M77 Other enthesopathies
0.000 0.496 0.504
H67.8 Otitis media in other diseases classified elsewhere
0.000 0.497 0.503
H67.1 Otitis media in viral diseases classified elsewhere
0.000 0.497 0.503
H67.0 Otitis media in bacterial diseases classified elsewhere
0.000 0.497 0.503
H68.1 Obstruction of Eustachian tube
0.000 0.497 0.503
H68.0 Eustachian salpingitis
0.000 0.497 0.503
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere
0.000 0.497 0.503
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere
0.000 0.497 0.503
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.498 0.502
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.498 0.502
H35.0 Background retinopathy and retinal vascular changes
0.000 0.499 0.501
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.500 0.500
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.500 0.500
E70.3 Albinism
0.000 0.500 0.500
E70.2 Disorders of tyrosine metabolism
0.000 0.500 0.500
E70.1 Other hyperphenylalaninaemias
0.000 0.500 0.500
E70.0 Classical phenylketonuria
0.000 0.500 0.500
E71.3 Disorders of fatty-acid metabolism
0.000 0.500 0.500
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.500 0.500
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.500 0.500
E71.0 Maple-syrup-urine disease
0.000 0.500 0.500
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.500 0.500
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.500 0.500
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.500 0.500
E76.2 Other mucopolysaccharidoses
0.000 0.500 0.500
E76.1 Mucopolysaccharidosis, type II
0.000 0.500 0.500
E76.0 Mucopolysaccharidosis, type I
0.000 0.500 0.500
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.500 0.500
E77.8 Other disorders of glycoprotein metabolism
0.000 0.500 0.500
E77.1 Defects in glycoprotein degradation
0.000 0.500 0.500
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.500 0.500
H69 Other disorders of Eustachian tube
0.000 0.501 0.499
M46.8 Other specified inflammatory spondylopathies
0.000 0.503 0.497
M46.5 Other infective spondylopathies
0.000 0.503 0.497
M46.2 Osteomyelitis of vertebra
0.000 0.503 0.497
M46.1 Sacro-iliitis, not elsewhere classified
0.000 0.504 0.495
P90-P96 Other disorders originating in the perinatal period
0.000 0.504 0.495
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn
0.000 0.504 0.495
P75-P78 Digestive system disorders of fetus and newborn
0.000 0.504 0.495
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn
0.000 0.504 0.495
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn
0.000 0.504 0.495
P35-P39 Infections specific to the perinatal period
0.000 0.504 0.495
P20-P29 Respiratory and cardiovascular disorders specific to the perinatal period
0.000 0.504 0.495
P10-P15 Birth trauma
0.000 0.504 0.495
P05-P08 Disorders related to length of gestation and fetal growth
0.000 0.504 0.495
P00-P04 Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery
0.000 0.504 0.495
M79.68 Pain in limb (Other)
0.000 0.506 0.494
M79.78 Fibromyalgia (Other)
0.000 0.507 0.493
M79.77 Fibromyalgia (Ankle and foot)
0.000 0.507 0.493
M79.76 Fibromyalgia (Lower leg)
0.000 0.507 0.493
M79.75 Fibromyalgia (Pelvic region and thigh)
0.000 0.507 0.493
M79.74 Fibromyalgia (Hand)
0.000 0.507 0.493
M79.73 Fibromyalgia (Forearm)
0.000 0.507 0.493
M79.72 Fibromyalgia (Upper arm)
0.000 0.507 0.493
M79.71 Fibromyalgia (Shoulder region)
0.000 0.507 0.493
M71.3 Other bursal cyst
0.000 0.507 0.493
Chapter X Diseases of the respiratory system
0.000 0.508 0.492
H90.3 Sensorineural hearing loss, bilateral
0.000 0.510 0.490
M88.8 Paget's disease of other bones
0.000 0.510 0.489
M88.0 Paget's disease of skull
0.000 0.510 0.489
M70.69 Trochanteric bursitis-Site unspec
0.000 0.512 0.487
M79.64 Pain in limb (Hand)
0.000 0.512 0.487
M49.5 Collapsed vertebra in diseases classified elsewhere
0.000 0.513 0.487
M49.8 Spondylopathy in other diseases classified elsewhere
0.000 0.514 0.486
M49.4 Neuropathic spondylopathy
0.000 0.514 0.486
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere
0.000 0.514 0.486
M49.2 Enterobacterial spondylitis
0.000 0.514 0.486
M49.1 Brucella spondylitis
0.000 0.514 0.486
M49.0 Tuberculosis of spine
0.000 0.514 0.486
M75.81 Other shoulder lesions, right shoulder
0.000 0.514 0.486
M73.8 Other soft tissue disorders in diseases classified elsewhere
0.000 0.515 0.484
M73.1 Syphilitic bursitis
0.000 0.515 0.484
M73.0 Gonococcal bursitis
0.000 0.515 0.484
M76.6 Achilles tendinitis
0.000 0.516 0.484
H70.1 Chronic mastoiditis
0.000 0.516 0.484
H61.8 Other specified disorders of external ear
0.000 0.516 0.484
H92.1 Otorrhoea
0.000 0.517 0.483
H47.0 Disorders of optic nerve, not elsewhere classified
0.000 0.518 0.482
H30 Chorioretinal inflammation
0.000 0.518 0.482
E75.6 Lipid storage disorder, unspecified
0.000 0.520 0.480
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.520 0.480
E75.3 Sphingolipidosis, unspecified
0.000 0.520 0.480
E75.2 Other sphingolipidosis
0.000 0.520 0.480
E75.1 Other gangliosidosis
0.000 0.520 0.480
E75.0 GM2 gangliosidosis
0.000 0.520 0.480
M88.98 Paget's disease of bone, unspecified (Other)
0.000 0.520 0.480
M88.97 Paget's disease of bone, unspecified (Ankle and foot)
0.000 0.520 0.480
M88.96 Paget's disease of bone, unspecified (Lower leg)
0.000 0.520 0.480
M88.95 Paget's disease of bone, unspecified (Pelvic region and thigh)
0.000 0.520 0.480
M88.94 Paget's disease of bone, unspecified (Hand)
0.000 0.520 0.480
M88.93 Paget's disease of bone, unspecified (Forearm)
0.000 0.520 0.480
M88.92 Paget's disease of bone, unspecified (Upper arm)
0.000 0.520 0.480
M88.91 Paget's disease of bone, unspecified (Shoulder region)
0.000 0.520 0.480
M79.70 Fibromyalgia (Multiple sites)
0.000 0.521 0.479
J40-J47 Chronic lower respiratory diseases
0.000 0.521 0.479
M79.69 Pain in limb (Site unspecified)
0.000 0.522 0.478
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.522 0.477
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.522 0.477
E79.1 Lesch-Nyhan syndrome
0.000 0.522 0.477
H31 Other disorders of choroid
0.000 0.524 0.476
M46.0 Spinal enthesopathy
0.000 0.525 0.475
L51 Erythema multiforme
0.000 0.525 0.475
M79.18 Myalgia (Other)
0.000 0.526 0.474
H70.8 Other mastoiditis and related conditions
0.000 0.526 0.474

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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