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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3135352
log Bayes Factor = 206.431
Chromosome 6   position 32,392,906  (GRCh37) Explore rs3135352 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
# Top node
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
K51.9 Ulcerative colitis, unspecified
1.000 0.000 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
Chapter VII Diseases of the eye and adnexa
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
E78.0 Pure hypercholesterolaemia
0.000 0.000 1.000
H36 Retinal disorders in diseases classified elsewhere
0.000 0.000 1.000
K51 Ulcerative colitis
1.000 0.000 0.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
H30-H36 Disorders of choroid and retina
0.000 0.000 1.000
M05 Seropositive rheumatoid arthritis
0.000 0.000 1.000
E10.4 With neurological complications
0.000 0.000 1.000
Chapter XI Diseases of the digestive system
0.000 0.000 1.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.001 0.999
Chapter IX Diseases of the circulatory system
0.000 0.001 0.999
I20-I25 Ischaemic heart diseases
0.000 0.001 0.999
I10-I15 Hypertensive diseases
0.000 0.001 0.999
E14.9 Without complications
0.000 0.001 0.999
K90 Intestinal malabsorption
0.000 0.002 0.998
K90-K93 Other diseases of the digestive system
0.000 0.002 0.998
G35-G37 Demyelinating diseases of the central nervous system
0.998 0.002 0.000
G37 Other demyelinating diseases of central nervous system
0.998 0.002 0.000
J33 Nasal polyp
0.000 0.003 0.997
J33.9 Nasal polyp, unspecified
0.000 0.003 0.997
G37.9 Demyelinating disease of central nervous system, unspecified
0.997 0.003 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.004 0.996
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.005 0.995
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.005 0.995
J45 Asthma
0.000 0.006 0.994
E14.3 With ophthalmic complications
0.000 0.006 0.994
K51.3 Ulcerative (chronic) rectosigmoiditis
0.993 0.007 0.000
K70-K77 Diseases of liver
0.000 0.007 0.993
I10 Essential (primary) hypertension
0.000 0.007 0.993
Chapter X Diseases of the respiratory system
0.000 0.007 0.993
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.008 0.992
J40-J47 Chronic lower respiratory diseases
0.000 0.008 0.992
E70-E90 Metabolic disorders
0.000 0.010 0.990
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.011 0.989
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.011 0.989
H43-H45 Disorders of vitreous body and globe
0.000 0.013 0.987
H40-H42 Glaucoma
0.000 0.014 0.986
J30-J39 Other diseases of upper respiratory tract
0.000 0.017 0.983
H43 Disorders of vitreous body
0.000 0.018 0.982
I22 Subsequent myocardial infarction
0.000 0.019 0.981
E05.9 Thyrotoxicosis, unspecified
0.000 0.020 0.980
E10.5 With peripheral circulatory complications
0.000 0.023 0.977
K74 Fibrosis and cirrhosis of liver
0.000 0.024 0.976
H40 Glaucoma
0.000 0.025 0.975
H40.9 Glaucoma, unspecified
0.000 0.027 0.973
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.028 0.972
E11.3 With ophthalmic complications
0.000 0.030 0.970
L40-L45 Papulosquamous disorders
0.000 0.030 0.970
I20 Angina pectoris
0.000 0.031 0.969
J33.8 Other polyp of sinus
0.000 0.031 0.969
L43 Lichen planus
0.000 0.034 0.966
L40 Psoriasis
0.000 0.034 0.966
K51.8 Other ulcerative colitis
0.966 0.034 0.000
L43.9 Lichen planus, unspecified
0.000 0.037 0.963
I12 Hypertensive renal disease
0.000 0.038 0.962
E11.1 With ketoacidosis
0.000 0.039 0.961
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.040 0.960
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.041 0.959
E06 Thyroiditis
0.000 0.042 0.958
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.045 0.955
L40.5 Arthropathic psoriasis
0.000 0.045 0.955
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.046 0.954
H43.3 Other vitreous opacities
0.000 0.049 0.951
H43.8 Other disorders of vitreous body
0.000 0.051 0.949
J33.0 Polyp of nasal cavity
0.000 0.053 0.947
K74.3 Primary biliary cirrhosis
0.000 0.054 0.946
K50-K52 Noninfective enteritis and colitis
0.014 0.056 0.930
K55-K64 Other diseases of intestines
0.000 0.057 0.943
M70-M79 Other soft tissue disorders
0.000 0.064 0.936
E06.3 Autoimmune thyroiditis
0.000 0.069 0.931
K60 Fissure and fistula of anal and rectal regions
0.000 0.069 0.931
E10.2 With renal complications
0.000 0.075 0.925
H34 Retinal vascular occlusions
0.000 0.079 0.921
I25 Chronic ischaemic heart disease
0.000 0.081 0.919
E11.5 With peripheral circulatory complications
0.000 0.088 0.912
I12.9 Hypertensive renal disease without renal failure
0.000 0.089 0.911
J46 Status asthmaticus
0.000 0.093 0.907
E11.2 With renal complications
0.000 0.096 0.904
I20.1 Angina pectoris with documented spasm
0.000 0.096 0.904
M75 Shoulder lesions
0.000 0.097 0.903
E13 Other specified diabetes mellitus
0.000 0.097 0.903
K72 Hepatic failure, not elsewhere classified
0.000 0.099 0.901
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.100 0.900
K51.2 Ulcerative (chronic) proctitis
0.900 0.100 0.000
M06.0 Seronegative rheumatoid arthritis
0.000 0.102 0.898
K58 Irritable bowel syndrome
0.000 0.107 0.893
Chapter VIII Diseases of the ear and mastoid process
0.000 0.107 0.893
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.110 0.890
K60.2 Anal fissure, unspecified
0.000 0.113 0.887
K50 Crohn's disease [regional enteritis]
0.001 0.115 0.885
L40.9 Psoriasis, unspecified
0.000 0.116 0.884
M75.0 Adhesive capsulitis of shoulder
0.000 0.118 0.882
I20.9 Angina pectoris, unspecified
0.000 0.118 0.882
H60-H62 Diseases of external ear
0.000 0.120 0.880
I20.0 Unstable angina
0.000 0.120 0.880
I24 Other acute ischaemic heart diseases
0.000 0.122 0.878
E03.8 Other specified hypothyroidism
0.000 0.123 0.877
K58.0 Irritable bowel syndrome with diarrhoea
0.000 0.123 0.877
M77 Other enthesopathies
0.000 0.125 0.875
K60.0 Acute anal fissure
0.000 0.126 0.874
H61 Other disorders of external ear
0.000 0.131 0.869
E07 Other disorders of thyroid
0.000 0.134 0.866
M77.1 Lateral epicondylitis
0.000 0.134 0.865
I15 Secondary hypertension
0.000 0.135 0.865
H40.1 Primary open-angle glaucoma
0.000 0.136 0.864
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.137 0.863
M77.12 Lateral epicondylitis (Upper arm)
0.000 0.141 0.859
I25.5 Ischaemic cardiomyopathy
0.000 0.146 0.854
K55 Vascular disorders of intestine
0.000 0.146 0.854
K60.5 Anorectal fistula
0.000 0.149 0.851
E11.6 With other specified complications
0.000 0.150 0.850
K75 Other inflammatory liver diseases
0.000 0.152 0.848
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.153 0.847
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.154 0.846
H61.0 Perichondritis of external ear
0.000 0.156 0.844
M06.4 Inflammatory polyarthropathy
0.000 0.159 0.841
J86 Pyothorax
0.000 0.159 0.841
G37.8 Other specified demyelinating diseases of central nervous system
0.834 0.166 0.000
E13.9 Without complications
0.000 0.167 0.833
K63 Other diseases of intestine
0.000 0.172 0.828
K73 Chronic hepatitis, not elsewhere classified
0.000 0.172 0.827
K74.6 Other and unspecified cirrhosis of liver
0.000 0.174 0.826
I12.0 Hypertensive renal disease with renal failure
0.000 0.178 0.822
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.179 0.821
K74.5 Biliary cirrhosis, unspecified
0.000 0.185 0.815
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.815 0.185 0.000
E78.1 Pure hyperglyceridaemia
0.000 0.185 0.814
M07 Psoriatic and enteropathic arthropathies
0.000 0.187 0.813
I25.2 Old myocardial infarction
0.000 0.190 0.810
K51.4 Pseudopolyposis of colon
0.810 0.190 0.000
J43 Emphysema
0.000 0.192 0.808
M06.3 Rheumatoid nodule
0.000 0.192 0.808
H40.5 Glaucoma secondary to other eye disorders
0.000 0.193 0.807
H34.2 Other retinal artery occlusions
0.000 0.194 0.806
M65-M68 Disorders of synovium and tendon
0.000 0.194 0.806
K50.8 Other Crohn's disease
0.000 0.194 0.806
M75.2 Bicipital tendinitis
0.000 0.196 0.804
M45-M49 Spondylopathies
0.000 0.197 0.803
H25-H28 Disorders of lens
0.000 0.197 0.803
K63.9 Disease of intestine, unspecified
0.000 0.200 0.800
K75.4 Autoimmune hepatitis
0.000 0.201 0.799
E40-E46 Malnutrition
0.000 0.202 0.798
J32 Chronic sinusitis
0.000 0.203 0.797
K72.9 Hepatic failure, unspecified
0.000 0.206 0.794
M45 Ankylosing spondylitis
0.000 0.210 0.790
K51.5 Mucosal proctocolitis
0.789 0.210 0.000
E07.9 Disorder of thyroid, unspecified
0.000 0.212 0.788
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.213 0.787
K50.1 Crohn's disease of large intestine
0.000 0.215 0.785
J37 Chronic laryngitis and laryngotracheitis
0.000 0.216 0.784
E16.1 Other hypoglycaemia
0.000 0.218 0.782
E88 Other metabolic disorders
0.000 0.218 0.782
K55.2 Angiodysplasia of colon
0.000 0.219 0.781
E78.5 Hyperlipidaemia, unspecified
0.000 0.220 0.780
M14 Arthropathies in other diseases classified elsewhere
0.000 0.224 0.776
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.225 0.775
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.226 0.774
E74 Other disorders of carbohydrate metabolism
0.000 0.227 0.772
L43.8 Other lichen planus
0.000 0.229 0.771
I15.1 Hypertension secondary to other renal disorders
0.000 0.230 0.770
E78.2 Mixed hyperlipidaemia
0.000 0.231 0.769
I23 Certain current complications following acute myocardial infarction
0.000 0.235 0.765
H34.8 Other retinal vascular occlusions
0.000 0.235 0.765
M75.4 Impingement syndrome of shoulder
0.000 0.237 0.763
J44 Other chronic obstructive pulmonary disease
0.000 0.239 0.761
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.240 0.760
J86.9 Pyothorax without fistula
0.000 0.242 0.758
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.243 0.757
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.000 0.243 0.757
K63.3 Ulcer of intestine
0.000 0.245 0.755
K90.9 Intestinal malabsorption, unspecified
0.000 0.249 0.750
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.251 0.749
H27 Other disorders of lens
0.000 0.252 0.748
K72.0 Acute and subacute hepatic failure
0.000 0.258 0.742
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.259 0.741
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.259 0.741
H61.8 Other specified disorders of external ear
0.000 0.259 0.741
H43.2 Crystalline deposits in vitreous body
0.000 0.259 0.741
M75.3 Calcific tendinitis of shoulder
0.000 0.260 0.740
H61.1 Non-infective disorders of pinna
0.000 0.261 0.739
K55.8 Other vascular disorders of intestine
0.000 0.265 0.735
L40.8 Other psoriasis
0.000 0.266 0.734
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.266 0.733
I25.1 Atherosclerotic heart disease
0.000 0.268 0.732
E11.8 With unspecified complications
0.000 0.270 0.730
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.275 0.725
H43.9 Disorder of vitreous body, unspecified
0.000 0.276 0.724
M65 Synovitis and tenosynovitis
0.000 0.276 0.724
H34.1 Central retinal artery occlusion
0.000 0.279 0.721
H40.4 Glaucoma secondary to eye inflammation
0.000 0.280 0.720
M11 Other crystal arthropathies
0.000 0.281 0.719
J86.0 Pyothorax with fistula
0.000 0.283 0.717
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
E10.8 With unspecified complications
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E10.6 With other specified complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
E14.8 With unspecified complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.6 With other specified complications
0.000 0.283 0.717
E14.5 With peripheral circulatory complications
0.000 0.283 0.717
E14.4 With neurological complications
0.000 0.283 0.717
E14.2 Withrenal complications
0.000 0.283 0.717
E14.1 With ketoacidosis
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.283 0.717
K51.1 Ulcerative (chronic) ileocolitis
0.717 0.283 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.283 0.717
M05.8 Other seropositive rheumatoid arthritis
0.000 0.283 0.717
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.283 0.717
M05.2 Rheumatoid vasculitis
0.000 0.283 0.717
M05.1 Rheumatoid lung disease
0.000 0.283 0.717
M05.0 Felty's syndrome
0.000 0.283 0.717
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.716
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.283 0.716
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.283 0.716
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.283 0.716
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.283 0.716
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.283 0.716
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.716
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.283 0.716
I00-I02 Acute rheumatic fever
0.000 0.283 0.716
I13 Hypertensive heart and renal disease
0.000 0.284 0.716
K90.3 Pancreatic steatorrhoea
0.000 0.284 0.716
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.284 0.716
K90.1 Tropical sprue
0.000 0.284 0.716
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.284 0.716
G36 Other acute disseminated demyelination
0.715 0.284 0.000
G37.5 Concentric sclerosis [Balo]
0.715 0.285 0.000
G37.4 Subacute necrotising myelitis
0.715 0.285 0.000
G37.2 Central pontine myelinolysis
0.715 0.285 0.000
G37.1 Central demyelination of corpus callosum
0.715 0.285 0.000
G37.0 Diffuse sclerosis
0.715 0.285 0.000
J33.1 Polypoid sinus degeneration
0.000 0.285 0.715
H30 Chorioretinal inflammation
0.000 0.286 0.714
J45.8 Mixed asthma
0.000 0.287 0.713
J45.1 Nonallergic asthma
0.000 0.287 0.713
K77 Liver disorders in diseases classified elsewhere
0.000 0.288 0.712
K71 Toxic liver disease
0.000 0.288 0.712
E78.6 Lipoprotein deficiency
0.000 0.288 0.711
E78.3 Hyperchylomicronaemia
0.000 0.288 0.711
E77 Disorders of glycoprotein metabolism
0.000 0.290 0.709
E76 Disorders of glycosaminoglycan metabolism
0.000 0.290 0.709
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.290 0.709
E72 Other disorders of amino-acid metabolism
0.000 0.290 0.709
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.290 0.709
E70 Disorders of aromatic amino-acid metabolism
0.000 0.290 0.709
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.290 0.709
E05.5 Thyroid crisis or storm
0.000 0.291 0.709
E05.4 Thyrotoxicosis factitia
0.000 0.291 0.709
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.291 0.709
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.291 0.709
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.000 0.293 0.707
H42 Glaucoma in diseases classified elsewhere
0.000 0.293 0.707
I11 Hypertensive heart disease
0.000 0.294 0.706
H43.0 Vitreous prolapse
0.000 0.296 0.704
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.296 0.704
K51.0 Ulcerative (chronic) enterocolitis
0.701 0.299 0.000
K52 Other non-infective gastro-enteritis and colitis
0.002 0.300 0.697
K74.4 Secondary biliary cirrhosis
0.000 0.300 0.700
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.300 0.700
K74.1 Hepatic sclerosis
0.000 0.300 0.700
H40.6 Glaucoma secondary to drugs
0.000 0.301 0.699
H40.3 Glaucoma secondary to eye trauma
0.000 0.301 0.699
M65.4 Radial styloid tenosynovitis [de Quervain]
0.000 0.303 0.697
E11.4 With neurological complications
0.000 0.304 0.696
E11.0 With coma
0.000 0.305 0.695
L44 Other papulosquamous disorders
0.000 0.305 0.695
L41 Parapsoriasis
0.000 0.305 0.695
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.305 0.695
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.000 0.305 0.695
H61.3 Acquired stenosis of external ear canal
0.000 0.306 0.694
L43.3 Subacute (active) lichen planus
0.000 0.307 0.693
L43.2 Lichenoid drug reaction
0.000 0.307 0.693
L43.1 Bullous lichen planus
0.000 0.307 0.693
L43.0 Hypertrophic lichen planus
0.000 0.307 0.693
L40.4 Guttate psoriasis
0.000 0.307 0.692
L40.3 Pustulosis palmaris et plantaris
0.000 0.307 0.692
L40.2 Acrodermatitis continua
0.000 0.307 0.692
L40.1 Generalised pustular psoriasis
0.000 0.307 0.692
H43.1 Vitreous haemorrhage
0.000 0.308 0.692
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.308 0.692
K63.4 Enteroptosis
0.000 0.309 0.690
H60 Otitis externa
0.000 0.310 0.690
J41 Simple and mucopurulent chronic bronchitis
0.000 0.311 0.689
E06.5 Other chronic thyroiditis
0.000 0.313 0.687
E06.4 Drug-induced thyroiditis
0.000 0.313 0.687
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.313 0.687
E06.1 Subacute thyroiditis
0.000 0.313 0.687
E06.0 Acute thyroiditis
0.000 0.313 0.687
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.315 0.685
M76 Enthesopathies of lower limb, excluding foot
0.000 0.315 0.684
M12 Other specific arthropathies
0.000 0.317 0.683
K73.9 Chronic hepatitis, unspecified
0.000 0.317 0.683
L40.0 Psoriasis vulgaris
0.000 0.320 0.680
M07.3 Other psoriatic arthropathies
0.000 0.320 0.680
E05.8 Other thyrotoxicosis
0.000 0.320 0.679
K82 Other diseases of gallbladder
0.000 0.320 0.680
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.321 0.679
K50.0 Crohn's disease of small intestine
0.000 0.323 0.677
K64 Haemorrhoids and perianal venous thrombosis
0.000 0.324 0.676
J32.4 Chronic pansinusitis
0.000 0.328 0.672
M73 Soft tissue disorders in diseases classified elsewhere
0.000 0.329 0.671
J95-J99 Other diseases of the respiratory system
0.000 0.330 0.670
I25.4 Coronary artery aneurysm
0.000 0.330 0.670
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.333 0.667
E06.9 Thyroiditis, unspecified
0.000 0.334 0.665
K82.8 Other specified diseases of gallbladder
0.000 0.336 0.664
M14.6 Neuropathic arthropathy
0.000 0.336 0.664
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.337 0.663
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.339 0.661
H34.0 Transient retinal artery occlusion
0.000 0.340 0.660
E84 Cystic fibrosis
0.000 0.340 0.659
I25.6 Silent myocardial ischaemia
0.000 0.341 0.659
J31.2 Chronic pharyngitis
0.000 0.345 0.655
M06.34 Rheumatoid nodule (Hand)
0.000 0.346 0.654
E46 Unspecified protein-energy malnutrition
0.000 0.346 0.654
H27.0 Aphakia
0.000 0.347 0.653
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.348 0.652
E83 Disorders of mineral metabolism
0.451 0.349 0.200
M75.8 Other shoulder lesions
0.000 0.352 0.648
E13.8 With unspecified complications
0.000 0.353 0.647
E13.7 With multiple complications
0.000 0.353 0.647
E13.6 With other specified complications
0.000 0.353 0.647
E13.5 With peripheral circulatory complications
0.000 0.353 0.647
E13.4 With neurological complications
0.000 0.353 0.647
E13.3 With ophthalmic complications
0.000 0.353 0.647
E13.2 With renal complications
0.000 0.353 0.647
E13.1 With ketoacidosis
0.000 0.353 0.647
E13.0 With coma
0.000 0.353 0.647
K72.1 Chronic hepatic failure
0.000 0.354 0.646
K55.1 Chronic vascular disorders of intestine
0.000 0.355 0.645
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.356 0.644
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.356 0.644
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.356 0.644
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.356 0.644
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.356 0.644
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.356 0.644
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.356 0.644
H34.9 Retinal vascular occlusion, unspecified
0.000 0.358 0.642
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.000 0.358 0.642
I21 Acute myocardial infarction
0.000 0.359 0.641
J37.0 Chronic laryngitis
0.000 0.359 0.641
J32.9 Chronic sinusitis, unspecified
0.000 0.361 0.639
H27.8 Other specified disorders of lens
0.000 0.363 0.637
E79 Disorders of purine and pyrimidine metabolism
0.000 0.363 0.637
J43.2 Centrilobular emphysema
0.000 0.363 0.637
H35 Other retinal disorders
0.000 0.364 0.636
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.365 0.635
L42 Pityriasis rosea
0.000 0.366 0.634
M70 Soft tissue disorders related to use, overuse and pressure
0.000 0.366 0.634
J43.9 Emphysema, unspecified
0.000 0.367 0.633
K52.1 Toxic gastro-enteritis and colitis
0.001 0.367 0.632
H62 Disorders of external ear in diseases classified elsewhere
0.000 0.369 0.631
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.369 0.631
M72 Fibroblastic disorders
0.000 0.370 0.630
K76 Other diseases of liver
0.000 0.370 0.630
M77.8 Other enthesopathies, not elsewhere classified
0.000 0.373 0.627
M77.3 Calcaneal spur
0.000 0.373 0.627
M77.2 Periarthritis of wrist
0.000 0.373 0.627
L10-L14 Bullous disorders
0.000 0.375 0.625
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.000 0.375 0.625
M10 Gout
0.000 0.375 0.625
E78.8 Other disorders of lipoprotein metabolism
0.000 0.377 0.623
E07.1 Dyshormogenetic goitre
0.000 0.379 0.621
E07.0 Hypersecretion of calcitonin
0.000 0.379 0.621
M77.19 Lateral epicondylitis (Site unspecified)
0.000 0.379 0.620
M77.18 Lateral epicondylitis-Other
0.000 0.379 0.620
M77.17 Lateral epicondylitis-Ankle/Foot
0.000 0.379 0.620
M77.16 Lateral epicondylitis (Lower leg)
0.000 0.379 0.620
M77.15 Lateral epicondylitis (Pelvic region and thigh)
0.000 0.379 0.620
M77.14 Lateral epicondylitis-Hand
0.000 0.379 0.620
M77.13 Lateral epicondylitis-Forearm
0.000 0.379 0.620
M77.11 Lateral epicondylitis-Shldr region
0.000 0.379 0.620
M77.10 Lateral epicondylitis (Multiple sites)
0.000 0.379 0.620
I15.9 Seconday hypertension, unspecified
0.000 0.379 0.620
I15.8 Other secondary hypertension
0.000 0.379 0.620
I15.2 Hypertension secondary to endocrine disorders
0.000 0.379 0.620
I15.0 Renovascular hypertension
0.000 0.379 0.620
H25 Senile cataract
0.000 0.380 0.620
K75.9 Inflammatory liver disease, unspecified
0.000 0.381 0.619
J85 Abscess of lung and mediastinum
0.000 0.382 0.618
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.383 0.617
K74.0 Hepatic fibrosis
0.000 0.387 0.613
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.389 0.611
H25.1 Senile nuclear cataract
0.000 0.392 0.608
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.392 0.608
K75.2 Nonspecific reactive hepatitis
0.000 0.392 0.608
K75.1 Phlebitis of portal vein
0.000 0.392 0.608
E73 Lactose intolerance
0.000 0.393 0.607
K76.8 Other specified diseases of liver
0.000 0.395 0.605
M77.5 Other enthesopathy of foot
0.000 0.395 0.605
K91.0 Vomiting following gastro-intestinal surgery
0.000 0.395 0.605
I25.3 Aneurysm of heart
0.000 0.396 0.604
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.397 0.603
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.397 0.603
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.397 0.603
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.397 0.603
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.397 0.603
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.397 0.603
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.397 0.603
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.397 0.603
M49 Spondylopathies in diseases classified elsewhere
0.000 0.397 0.603
J32.8 Other chronic sinusitis
0.000 0.397 0.603
E88.2 Lipomatosis, not elsewhere classified
0.000 0.397 0.602
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.398 0.602
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.399 0.601
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.402 0.598
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.403 0.597
I23.8 Other current complications following acute myocardial infarction
0.000 0.403 0.597
K60.4 Rectal fistula
0.000 0.406 0.594
H61.9 Disorder of external ear, unspecified
0.000 0.407 0.593
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.407 0.593
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.407 0.593
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.407 0.593
M60-M63 Disorders of muscles
0.000 0.407 0.592
H60.9 Otitis externa, unspecified
0.000 0.411 0.589
K82.1 Hydrops of gallbladder
0.000 0.414 0.586
K60.1 Chronic anal fissure
0.000 0.416 0.584
J42 Unspecified chronic bronchitis
0.000 0.416 0.584
M07.6 Other enteropathic arthropathies
0.000 0.417 0.583
M07.5 Arthropathy in ulcerative colitis
0.000 0.417 0.583
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.417 0.583
M07.2 Psoriatic spondylitis
0.000 0.417 0.583
M07.1 Arthritis mutilans
0.000 0.417 0.583
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.417 0.583
H27.1 Dislocation of lens
0.000 0.419 0.581
M77.0 Medial epicondylitis
0.000 0.419 0.580
J43.8 Other emphysema
0.000 0.420 0.580
J43.1 Panlobular emphysema
0.000 0.420 0.580
J43.0 MacLeod's syndrome
0.000 0.420 0.580
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.421 0.579
M06.38 Rheumatoid nodule (Other)
0.000 0.421 0.579
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.421 0.579
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.421 0.579
M06.33 Rheumatoid nodule (Forearm)
0.000 0.421 0.579
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.421 0.579
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.421 0.579
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.421 0.579
H65-H75 Diseases of middle ear and mastoid
0.000 0.421 0.579
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.421 0.579
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.000 0.422 0.578
K90.8 Other intestinal malabsorption
0.000 0.422 0.577
M00-M03 Infectious arthropathies
0.000 0.422 0.577
I21.4 Acute subendocardial myocardial infarction
0.000 0.424 0.576
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.000 0.424 0.576
K50.9 Crohn's disease, unspecified
0.000 0.425 0.575
K55.9 Vascular disorder of intestine, unspecified
0.000 0.427 0.573
M71 Other bursopathies
0.000 0.427 0.573
K52.8 Other specified non-infective gastro-enteritis and colitis
0.001 0.427 0.572
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.427 0.572
E45 Retarded development following protein-energy malnutrition
0.000 0.427 0.572
E43 Unspecified severe protein-energy malnutrition
0.000 0.427 0.572
E42 Marasmic kwashiorkor
0.000 0.427 0.572

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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