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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3135391
log Bayes Factor = 205.982
Chromosome 6   position 32,410,987  (GRCh37) Explore rs3135391 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
# Top node
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
K51.9 Ulcerative colitis, unspecified
1.000 0.000 0.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
K51 Ulcerative colitis
1.000 0.000 0.000
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
E78.0 Pure hypercholesterolaemia
0.000 0.000 1.000
Chapter VII Diseases of the eye and adnexa
0.000 0.000 1.000
H36 Retinal disorders in diseases classified elsewhere
0.000 0.000 1.000
M05 Seropositive rheumatoid arthritis
0.000 0.000 1.000
H30-H36 Disorders of choroid and retina
0.000 0.000 1.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.000 1.000
E10.4 With neurological complications
0.000 0.000 1.000
J45.9 Asthma, unspecified
0.000 0.001 0.999
Chapter XI Diseases of the digestive system
0.000 0.001 0.999
E14.9 Without complications
0.000 0.001 0.999
K90 Intestinal malabsorption
0.000 0.002 0.998
Chapter IX Diseases of the circulatory system
0.000 0.002 0.998
K90-K93 Other diseases of the digestive system
0.000 0.002 0.998
I20-I25 Ischaemic heart diseases
0.000 0.002 0.998
J33.9 Nasal polyp, unspecified
0.000 0.002 0.998
G35-G37 Demyelinating diseases of the central nervous system
0.997 0.002 0.001
I10-I15 Hypertensive diseases
0.000 0.002 0.998
J33 Nasal polyp
0.000 0.002 0.998
G37 Other demyelinating diseases of central nervous system
0.997 0.003 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.004 0.996
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.004 0.996
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.004 0.996
G37.9 Demyelinating disease of central nervous system, unspecified
0.996 0.004 0.000
K70-K77 Diseases of liver
0.000 0.005 0.995
K51.3 Ulcerative (chronic) rectosigmoiditis
0.995 0.005 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.006 0.994
E14.3 With ophthalmic complications
0.000 0.006 0.994
J45 Asthma
0.000 0.008 0.992
E70-E90 Metabolic disorders
0.000 0.009 0.991
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.009 0.991
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.009 0.991
I10 Essential (primary) hypertension
0.000 0.009 0.991
Chapter X Diseases of the respiratory system
0.000 0.010 0.990
J40-J47 Chronic lower respiratory diseases
0.000 0.010 0.990
H43-H45 Disorders of vitreous body and globe
0.000 0.011 0.989
H43 Disorders of vitreous body
0.000 0.015 0.985
E05.9 Thyrotoxicosis, unspecified
0.000 0.016 0.984
I20 Angina pectoris
0.000 0.019 0.981
H40-H42 Glaucoma
0.000 0.019 0.981
K74 Fibrosis and cirrhosis of liver
0.000 0.019 0.981
J30-J39 Other diseases of upper respiratory tract
0.000 0.020 0.980
I22 Subsequent myocardial infarction
0.000 0.024 0.976
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.027 0.973
L40-L45 Papulosquamous disorders
0.000 0.029 0.971
E10.5 With peripheral circulatory complications
0.000 0.029 0.971
L40 Psoriasis
0.000 0.031 0.969
H40 Glaucoma
0.000 0.033 0.967
K51.8 Other ulcerative colitis
0.967 0.033 0.000
L43 Lichen planus
0.000 0.033 0.967
J33.8 Other polyp of sinus
0.000 0.034 0.966
E11.3 With ophthalmic complications
0.000 0.035 0.965
H40.9 Glaucoma, unspecified
0.000 0.035 0.965
L43.9 Lichen planus, unspecified
0.000 0.038 0.962
E11.1 With ketoacidosis
0.000 0.039 0.961
L40.5 Arthropathic psoriasis
0.000 0.042 0.958
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.043 0.957
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.045 0.955
J33.0 Polyp of nasal cavity
0.000 0.045 0.955
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.047 0.952
H43.3 Other vitreous opacities
0.000 0.048 0.952
I12 Hypertensive renal disease
0.000 0.048 0.952
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.049 0.951
K74.3 Primary biliary cirrhosis
0.000 0.049 0.951
E06 Thyroiditis
0.000 0.051 0.949
H43.8 Other disorders of vitreous body
0.000 0.059 0.941
K50-K52 Noninfective enteritis and colitis
0.017 0.066 0.917
I20.9 Angina pectoris, unspecified
0.000 0.072 0.928
M70-M79 Other soft tissue disorders
0.000 0.073 0.927
K51.2 Ulcerative (chronic) proctitis
0.923 0.077 0.000
H34 Retinal vascular occlusions
0.000 0.077 0.923
E11.5 With peripheral circulatory complications
0.000 0.078 0.922
E10.2 With renal complications
0.000 0.078 0.922
E13 Other specified diabetes mellitus
0.000 0.084 0.916
I20.1 Angina pectoris with documented spasm
0.000 0.084 0.916
E06.3 Autoimmune thyroiditis
0.000 0.085 0.915
L40.9 Psoriasis, unspecified
0.000 0.090 0.910
J46 Status asthmaticus
0.000 0.094 0.906
K72 Hepatic failure, not elsewhere classified
0.000 0.096 0.904
Chapter VIII Diseases of the ear and mastoid process
0.000 0.100 0.900
M06.0 Seronegative rheumatoid arthritis
0.000 0.101 0.899
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.101 0.899
I20.0 Unstable angina
0.000 0.103 0.897
I12.9 Hypertensive renal disease without renal failure
0.000 0.104 0.896
E11.2 With renal complications
0.000 0.105 0.895
H60-H62 Diseases of external ear
0.000 0.109 0.891
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.114 0.886
K55-K64 Other diseases of intestines
0.000 0.115 0.885
M75 Shoulder lesions
0.000 0.116 0.884
H61 Other disorders of external ear
0.000 0.116 0.884
E07 Other disorders of thyroid
0.000 0.117 0.883
E11.6 With other specified complications
0.000 0.117 0.883
I25 Chronic ischaemic heart disease
0.000 0.120 0.880
E03.8 Other specified hypothyroidism
0.000 0.122 0.878
K60 Fissure and fistula of anal and rectal regions
0.000 0.129 0.871
K50 Crohn's disease [regional enteritis]
0.001 0.134 0.866
I15 Secondary hypertension
0.000 0.135 0.865
M77 Other enthesopathies
0.000 0.136 0.864
H61.0 Perichondritis of external ear
0.000 0.141 0.859
M75.0 Adhesive capsulitis of shoulder
0.000 0.142 0.858
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.143 0.857
E13.9 Without complications
0.000 0.143 0.857
M77.1 Lateral epicondylitis
0.000 0.145 0.855
K75 Other inflammatory liver diseases
0.000 0.148 0.852
M77.12 Lateral epicondylitis (Upper arm)
0.000 0.151 0.849
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.158 0.842
M06.4 Inflammatory polyarthropathy
0.000 0.159 0.841
J86 Pyothorax
0.000 0.160 0.840
H40.1 Primary open-angle glaucoma
0.000 0.163 0.837
I24 Other acute ischaemic heart diseases
0.000 0.164 0.836
G37.8 Other specified demyelinating diseases of central nervous system
0.833 0.167 0.000
K74.6 Other and unspecified cirrhosis of liver
0.000 0.168 0.832
K58 Irritable bowel syndrome
0.000 0.169 0.831
M65-M68 Disorders of synovium and tendon
0.000 0.176 0.824
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.179 0.821
K74.5 Biliary cirrhosis, unspecified
0.000 0.181 0.819
I25.5 Ischaemic cardiomyopathy
0.000 0.181 0.819
E78.2 Mixed hyperlipidaemia
0.000 0.182 0.818
K60.0 Acute anal fissure
0.000 0.182 0.818
K60.2 Anal fissure, unspecified
0.000 0.182 0.818
E07.9 Disorder of thyroid, unspecified
0.000 0.185 0.815
M07 Psoriatic and enteropathic arthropathies
0.000 0.185 0.815
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.814 0.186 0.000
K58.0 Irritable bowel syndrome with diarrhoea
0.000 0.187 0.813
K73 Chronic hepatitis, not elsewhere classified
0.000 0.188 0.812
M45-M49 Spondylopathies
0.000 0.190 0.810
K51.4 Pseudopolyposis of colon
0.809 0.191 0.000
H34.2 Other retinal artery occlusions
0.000 0.192 0.808
J43 Emphysema
0.000 0.195 0.805
M06.3 Rheumatoid nodule
0.000 0.197 0.803
H43.1 Vitreous haemorrhage
0.000 0.197 0.803
H25-H28 Disorders of lens
0.000 0.198 0.802
E88 Other metabolic disorders
0.000 0.198 0.802
H40.5 Glaucoma secondary to other eye disorders
0.000 0.198 0.802
K75.4 Autoimmune hepatitis
0.000 0.199 0.801
E40-E46 Malnutrition
0.000 0.200 0.799
K72.9 Hepatic failure, unspecified
0.000 0.202 0.798
M45 Ankylosing spondylitis
0.000 0.204 0.796
I12.0 Hypertensive renal disease with renal failure
0.000 0.205 0.795
K60.5 Anorectal fistula
0.000 0.206 0.794
K50.8 Other Crohn's disease
0.000 0.207 0.792
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.208 0.792
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.211 0.789
K51.5 Mucosal proctocolitis
0.789 0.211 0.000
J32 Chronic sinusitis
0.000 0.212 0.788
E78.5 Hyperlipidaemia, unspecified
0.000 0.213 0.787
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.213 0.787
E78.1 Pure hyperglyceridaemia
0.000 0.214 0.786
M75.2 Bicipital tendinitis
0.000 0.216 0.784
K90.9 Intestinal malabsorption, unspecified
0.000 0.216 0.784
E16.1 Other hypoglycaemia
0.000 0.217 0.783
J37 Chronic laryngitis and laryngotracheitis
0.000 0.218 0.782
H61.1 Non-infective disorders of pinna
0.000 0.219 0.781
M14 Arthropathies in other diseases classified elsewhere
0.000 0.223 0.777
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.224 0.776
E74 Other disorders of carbohydrate metabolism
0.000 0.226 0.774
L43.8 Other lichen planus
0.000 0.228 0.772
I15.1 Hypertension secondary to other renal disorders
0.000 0.230 0.770
H34.8 Other retinal vascular occlusions
0.000 0.231 0.769
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.232 0.768
K55 Vascular disorders of intestine
0.000 0.235 0.765
I23 Certain current complications following acute myocardial infarction
0.000 0.236 0.764
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.238 0.762
H61.8 Other specified disorders of external ear
0.000 0.241 0.759
J86.9 Pyothorax without fistula
0.000 0.241 0.759
K63 Other diseases of intestine
0.000 0.241 0.759
K50.1 Crohn's disease of large intestine
0.000 0.243 0.757
J44 Other chronic obstructive pulmonary disease
0.000 0.245 0.755
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.250 0.750
H27 Other disorders of lens
0.000 0.254 0.746
M65 Synovitis and tenosynovitis
0.000 0.254 0.746
M75.4 Impingement syndrome of shoulder
0.000 0.254 0.746
K72.0 Acute and subacute hepatic failure
0.000 0.255 0.745
H43.2 Crystalline deposits in vitreous body
0.000 0.257 0.743
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.261 0.739
K63.9 Disease of intestine, unspecified
0.000 0.264 0.736
L40.8 Other psoriasis
0.000 0.264 0.736
M11 Other crystal arthropathies
0.000 0.266 0.734
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.000 0.269 0.731
E11.8 With unspecified complications
0.000 0.270 0.730
K51.0 Ulcerative (chronic) enterocolitis
0.728 0.272 0.000
H43.9 Disorder of vitreous body, unspecified
0.000 0.274 0.726
M75.3 Calcific tendinitis of shoulder
0.000 0.274 0.726
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.275 0.725
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.275 0.725
K76 Other diseases of liver
0.000 0.275 0.725
H34.1 Central retinal artery occlusion
0.000 0.278 0.722
I25.2 Old myocardial infarction
0.000 0.278 0.722
M65.4 Radial styloid tenosynovitis [de Quervain]
0.000 0.282 0.718
J86.0 Pyothorax with fistula
0.000 0.283 0.717
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
E10.8 With unspecified complications
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E10.6 With other specified complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E14.8 With unspecified complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.6 With other specified complications
0.000 0.283 0.717
E14.5 With peripheral circulatory complications
0.000 0.283 0.717
E14.4 With neurological complications
0.000 0.283 0.717
E14.2 Withrenal complications
0.000 0.283 0.717
E14.1 With ketoacidosis
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
K51.1 Ulcerative (chronic) ileocolitis
0.717 0.283 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.283 0.717
M05.8 Other seropositive rheumatoid arthritis
0.000 0.283 0.717
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.283 0.717
M05.2 Rheumatoid vasculitis
0.000 0.283 0.717
M05.1 Rheumatoid lung disease
0.000 0.283 0.717
M05.0 Felty's syndrome
0.000 0.283 0.717
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.283 0.717
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.283 0.717
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.283 0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.283 0.717
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.283 0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.283 0.717
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.717
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.283 0.717
K90.3 Pancreatic steatorrhoea
0.000 0.284 0.716
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.284 0.716
K90.1 Tropical sprue
0.000 0.284 0.716
I00-I02 Acute rheumatic fever
0.000 0.284 0.716
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.284 0.716
G36 Other acute disseminated demyelination
0.715 0.285 0.001
I13 Hypertensive heart and renal disease
0.000 0.285 0.715
J33.1 Polypoid sinus degeneration
0.000 0.285 0.715
G37.5 Concentric sclerosis [Balo]
0.715 0.285 0.000
G37.4 Subacute necrotising myelitis
0.715 0.285 0.000
G37.2 Central pontine myelinolysis
0.715 0.285 0.000
G37.1 Central demyelination of corpus callosum
0.715 0.285 0.000
G37.0 Diffuse sclerosis
0.715 0.285 0.000
H40.4 Glaucoma secondary to eye inflammation
0.000 0.286 0.714
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.286 0.714
H30 Chorioretinal inflammation
0.000 0.286 0.714
K77 Liver disorders in diseases classified elsewhere
0.000 0.286 0.713
K71 Toxic liver disease
0.000 0.286 0.713
E78.6 Lipoprotein deficiency
0.000 0.287 0.713
E78.3 Hyperchylomicronaemia
0.000 0.287 0.713
J45.8 Mixed asthma
0.000 0.289 0.711
J45.1 Nonallergic asthma
0.000 0.289 0.711
E77 Disorders of glycoprotein metabolism
0.000 0.289 0.711
E76 Disorders of glycosaminoglycan metabolism
0.000 0.289 0.711
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.289 0.711
E72 Other disorders of amino-acid metabolism
0.000 0.289 0.711
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.289 0.711
E70 Disorders of aromatic amino-acid metabolism
0.000 0.289 0.711
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.289 0.711
E05.5 Thyroid crisis or storm
0.000 0.289 0.711
E05.4 Thyrotoxicosis factitia
0.000 0.289 0.711
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.289 0.711
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.289 0.711
E11.4 With neurological complications
0.000 0.290 0.710
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.291 0.709
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.000 0.291 0.709
H61.3 Acquired stenosis of external ear canal
0.000 0.293 0.707
I11 Hypertensive heart disease
0.000 0.293 0.706
H43.0 Vitreous prolapse
0.000 0.294 0.706
K76.8 Other specified diseases of liver
0.000 0.295 0.705
E11.0 With coma
0.000 0.296 0.704
H42 Glaucoma in diseases classified elsewhere
0.000 0.297 0.703
K74.4 Secondary biliary cirrhosis
0.000 0.297 0.703
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.297 0.703
K74.1 Hepatic sclerosis
0.000 0.297 0.703
L44 Other papulosquamous disorders
0.000 0.304 0.696
L41 Parapsoriasis
0.000 0.304 0.696
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.304 0.696
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.000 0.304 0.696
L40.4 Guttate psoriasis
0.000 0.305 0.694
L40.3 Pustulosis palmaris et plantaris
0.000 0.305 0.694
L40.2 Acrodermatitis continua
0.000 0.305 0.694
L40.1 Generalised pustular psoriasis
0.000 0.305 0.694
H40.6 Glaucoma secondary to drugs
0.000 0.306 0.694
H40.3 Glaucoma secondary to eye trauma
0.000 0.306 0.694
L43.3 Subacute (active) lichen planus
0.000 0.307 0.693
L43.2 Lichenoid drug reaction
0.000 0.307 0.693
L43.1 Bullous lichen planus
0.000 0.307 0.693
L43.0 Hypertrophic lichen planus
0.000 0.307 0.693
J41 Simple and mucopurulent chronic bronchitis
0.000 0.312 0.688
H35 Other retinal disorders
0.000 0.313 0.687
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.314 0.686
K63.3 Ulcer of intestine
0.000 0.315 0.685
M12 Other specific arthropathies
0.000 0.316 0.683
L40.0 Psoriasis vulgaris
0.000 0.317 0.683
K82 Other diseases of gallbladder
0.000 0.317 0.683
M07.3 Other psoriatic arthropathies
0.000 0.317 0.683
K52 Other non-infective gastro-enteritis and colitis
0.003 0.318 0.679
E05.8 Other thyrotoxicosis
0.000 0.319 0.681
E06.5 Other chronic thyroiditis
0.000 0.320 0.680
E06.4 Drug-induced thyroiditis
0.000 0.320 0.680
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.320 0.680
E06.1 Subacute thyroiditis
0.000 0.320 0.680
E06.0 Acute thyroiditis
0.000 0.320 0.680
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.321 0.679
M76 Enthesopathies of lower limb, excluding foot
0.000 0.321 0.679
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.322 0.678
K55.2 Angiodysplasia of colon
0.000 0.326 0.674
K82.8 Other specified diseases of gallbladder
0.000 0.330 0.670
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.332 0.668
K74.0 Hepatic fibrosis
0.000 0.333 0.667
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.334 0.665
J32.4 Chronic pansinusitis
0.000 0.335 0.665
M14.6 Neuropathic arthropathy
0.000 0.335 0.665
K50.0 Crohn's disease of small intestine
0.000 0.335 0.665
M73 Soft tissue disorders in diseases classified elsewhere
0.000 0.336 0.664
I25.1 Atherosclerotic heart disease
0.000 0.337 0.663
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.000 0.338 0.662
H34.0 Transient retinal artery occlusion
0.000 0.338 0.661
E84 Cystic fibrosis
0.000 0.339 0.661
E06.9 Thyroiditis, unspecified
0.000 0.341 0.659
K55.8 Other vascular disorders of intestine
0.000 0.341 0.659
E13.8 With unspecified complications
0.000 0.343 0.657
E13.7 With multiple complications
0.000 0.343 0.657
E13.6 With other specified complications
0.000 0.343 0.657
E13.5 With peripheral circulatory complications
0.000 0.343 0.657
E13.4 With neurological complications
0.000 0.343 0.657
E13.3 With ophthalmic complications
0.000 0.343 0.657
E13.2 With renal complications
0.000 0.343 0.657
E13.1 With ketoacidosis
0.000 0.343 0.657
E13.0 With coma
0.000 0.343 0.657
E46 Unspecified protein-energy malnutrition
0.000 0.344 0.656
H60 Otitis externa
0.000 0.345 0.655
H27.0 Aphakia
0.000 0.348 0.652
K73.9 Chronic hepatitis, unspecified
0.000 0.348 0.652
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.350 0.649
K72.1 Chronic hepatic failure
0.000 0.352 0.648
M06.34 Rheumatoid nodule (Hand)
0.000 0.354 0.645
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.355 0.645
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.355 0.645
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.355 0.645
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.355 0.645
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.355 0.645
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.355 0.645
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.355 0.645
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.000 0.356 0.644
H34.9 Retinal vascular occlusion, unspecified
0.000 0.356 0.644
M72 Fibroblastic disorders
0.000 0.358 0.642
I25.4 Coronary artery aneurysm
0.000 0.358 0.642
J37.0 Chronic laryngitis
0.000 0.361 0.639
H62 Disorders of external ear in diseases classified elsewhere
0.000 0.361 0.639
E79 Disorders of purine and pyrimidine metabolism
0.000 0.362 0.638
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.363 0.637
J95-J99 Other diseases of the respiratory system
0.000 0.363 0.637
L42 Pityriasis rosea
0.000 0.364 0.636
K64 Haemorrhoids and perianal venous thrombosis
0.000 0.365 0.635
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.365 0.634
J43.2 Centrilobular emphysema
0.000 0.366 0.634
M75.8 Other shoulder lesions
0.000 0.366 0.634
E07.1 Dyshormogenetic goitre
0.000 0.367 0.633
E07.0 Hypersecretion of calcitonin
0.000 0.367 0.633
J32.9 Chronic sinusitis, unspecified
0.000 0.367 0.633
K63.4 Enteroptosis
0.000 0.367 0.633
H27.8 Other specified disorders of lens
0.000 0.368 0.632
I25.6 Silent myocardial ischaemia
0.000 0.369 0.631
M70 Soft tissue disorders related to use, overuse and pressure
0.000 0.370 0.630
J43.9 Emphysema, unspecified
0.000 0.372 0.628
E78.8 Other disorders of lipoprotein metabolism
0.000 0.375 0.625
H25 Senile cataract
0.000 0.375 0.625
L10-L14 Bullous disorders
0.000 0.375 0.624
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.377 0.623
E83 Disorders of mineral metabolism
0.408 0.379 0.213
I15.9 Seconday hypertension, unspecified
0.000 0.380 0.620
I15.8 Other secondary hypertension
0.000 0.380 0.620
I15.2 Hypertension secondary to endocrine disorders
0.000 0.380 0.620
I15.0 Renovascular hypertension
0.000 0.380 0.620
M77.8 Other enthesopathies, not elsewhere classified
0.000 0.380 0.619
M77.3 Calcaneal spur
0.000 0.380 0.619
M77.2 Periarthritis of wrist
0.000 0.380 0.619
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.381 0.619
E88.2 Lipomatosis, not elsewhere classified
0.000 0.382 0.618
J85 Abscess of lung and mediastinum
0.000 0.382 0.617
K75.9 Inflammatory liver disease, unspecified
0.000 0.383 0.616
K52.1 Toxic gastro-enteritis and colitis
0.001 0.384 0.615
H25.1 Senile nuclear cataract
0.000 0.386 0.614
M77.19 Lateral epicondylitis (Site unspecified)
0.000 0.387 0.613
M77.18 Lateral epicondylitis-Other
0.000 0.387 0.613
M77.17 Lateral epicondylitis-Ankle/Foot
0.000 0.387 0.613
M77.16 Lateral epicondylitis (Lower leg)
0.000 0.387 0.613
M77.15 Lateral epicondylitis (Pelvic region and thigh)
0.000 0.387 0.613
M77.14 Lateral epicondylitis-Hand
0.000 0.387 0.613
M77.13 Lateral epicondylitis-Forearm
0.000 0.387 0.613
M77.11 Lateral epicondylitis-Shldr region
0.000 0.387 0.613
M77.10 Lateral epicondylitis (Multiple sites)
0.000 0.387 0.613
M10 Gout
0.000 0.388 0.612
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.389 0.611
K75.2 Nonspecific reactive hepatitis
0.000 0.389 0.611
K75.1 Phlebitis of portal vein
0.000 0.389 0.611
M49 Spondylopathies in diseases classified elsewhere
0.000 0.392 0.608
E73 Lactose intolerance
0.000 0.392 0.608
J31.2 Chronic pharyngitis
0.000 0.392 0.608
I21 Acute myocardial infarction
0.000 0.395 0.605
H61.9 Disorder of external ear, unspecified
0.000 0.396 0.604
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.397 0.603
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.397 0.603
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.397 0.603
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.397 0.603
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.397 0.603
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.397 0.603
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.397 0.603
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.397 0.603
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.398 0.602
M60-M63 Disorders of muscles
0.000 0.399 0.600
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.401 0.599
M77.5 Other enthesopathy of foot
0.000 0.402 0.598
M71 Other bursopathies
0.000 0.402 0.598
J32.8 Other chronic sinusitis
0.000 0.403 0.597
I23.8 Other current complications following acute myocardial infarction
0.000 0.403 0.597
K91.0 Vomiting following gastro-intestinal surgery
0.000 0.407 0.593
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.000 0.409 0.591
K82.1 Hydrops of gallbladder
0.000 0.410 0.590
M65.9 Synovitis and tenosynovitis, unspecified
0.000 0.414 0.586
J42 Unspecified chronic bronchitis
0.000 0.415 0.585
M07.6 Other enteropathic arthropathies
0.000 0.415 0.584
M07.5 Arthropathy in ulcerative colitis
0.000 0.415 0.584
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.415 0.584
M07.2 Psoriatic spondylitis
0.000 0.415 0.584
M07.1 Arthritis mutilans
0.000 0.415 0.584
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.415 0.584
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.415 0.585
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.001 0.416 0.583
M86-M90 Other osteopathies
0.001 0.417 0.582
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.418 0.582
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.418 0.582
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.418 0.582
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.418 0.582
M91-M94 Chondropathies
0.000 0.419 0.581
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.420 0.580
H27.1 Dislocation of lens
0.000 0.420 0.580
I25.3 Aneurysm of heart
0.000 0.421 0.579
K55.1 Chronic vascular disorders of intestine
0.000 0.421 0.579
K90.8 Other intestinal malabsorption
0.000 0.422 0.578
J43.8 Other emphysema
0.000 0.423 0.577
J43.1 Panlobular emphysema
0.000 0.423 0.577
J43.0 MacLeod's syndrome
0.000 0.423 0.577
K60.1 Chronic anal fissure
0.000 0.423 0.577
M00-M03 Infectious arthropathies
0.000 0.423 0.577
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.423 0.577
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.424 0.576
M06.38 Rheumatoid nodule (Other)
0.000 0.424 0.576
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.424 0.576
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.424 0.576
M06.33 Rheumatoid nodule (Forearm)
0.000 0.424 0.576
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.424 0.576
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.424 0.576
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.424 0.576
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.000 0.425 0.575
E07.8 Other specified disorders of thyroid
0.000 0.425 0.575
E88.9 Metabolic disorder, unspecified
0.000 0.425 0.575
E88.8 Other specified metabolic disorders
0.000 0.425 0.575
E88.3 Tumour lysis syndrome
0.000 0.425 0.575
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.425 0.575
M77.0 Medial epicondylitis
0.000 0.426 0.573
H35.5 Hereditary retinal dystrophy
0.000 0.427 0.573
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.427 0.573

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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