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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3217863
log Bayes Factor = 9.55969
Chromosome 12   position 4,399,496  (GRCh37) Explore rs3217863 on Ensembl!
Variant rs3217863 is part of Cluster X0193

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.9 Rheumatoid arthritis, unspecified
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
M06 Other rheumatoid arthritis
1.000 0.000 0.000
M05-M14 Inflammatory polyarthropathies
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
1.000 0.000 0.000
E10-E14 Diabetes mellitus
0.999 0.001 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.998 0.002 0.000
E11 Non-insulin-dependent diabetes mellitus
0.997 0.003 0.000
Chapter XX External causes of morbidity and mortality
0.995 0.005 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.992 0.008 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.988 0.012 0.000
Chapter II Neoplasms
0.988 0.012 0.000
C51-C58 Malignant neoplasms of female genital organs
0.987 0.013 0.000
E11.3 With ophthalmic complications
0.984 0.016 0.000
C54 Malignant neoplasm of corpus uteri
0.981 0.019 0.000
E11.9 Without complications
0.981 0.019 0.000
M86-M90 Other osteopathies
0.979 0.021 0.000
C54.1 Endometrium
0.977 0.023 0.000
T40.2 Other opioids
0.973 0.027 0.000
M07 Psoriatic and enteropathic arthropathies
0.973 0.027 0.000
E10 Insulin-dependent diabetes mellitus
0.969 0.031 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.969 0.031 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.967 0.033 0.000
E20-E35 Disorders of other endocrine glands
0.960 0.040 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.955 0.045 0.000
M07.3 Other psoriatic arthropathies
0.954 0.046 0.000
Y95 Nosocomial condition
0.950 0.050 0.000
M89 Other disorders of bone
0.937 0.063 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.931 0.069 0.000
Chapter VI Diseases of the nervous system
0.928 0.072 0.000
C56 Malignant neoplasm of ovary
0.926 0.074 0.000
Chapter VII Diseases of the eye and adnexa
0.922 0.078 0.000
E50-E64 Other nutritional deficiencies
0.912 0.088 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.910 0.090 0.000
C45 Mesothelioma
0.908 0.092 0.000
M89.9 Disorder of bone, unspecified
0.905 0.095 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.903 0.097 0.000
E27 Other disorders of adrenal gland
0.901 0.099 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.895 0.105 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.890 0.110 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.888 0.112 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.888 0.112 0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)
0.885 0.115 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.878 0.122 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.876 0.124 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.872 0.128 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.872 0.128 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.871 0.129 0.000
E10.1 With ketoacidosis
0.871 0.129 0.000
S50-S59 Injuries to the elbow and forearm
0.863 0.136 0.000
C78.0 Secondary malignant neoplasm of lung
0.863 0.137 0.000
E53 Deficiency of other B group vitamins
0.861 0.139 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.860 0.140 0.000
E23 Hypofunction and other disorders of pituitary gland
0.858 0.142 0.000
H04 Disorders of lachrymal system
0.858 0.142 0.000
E10.2 With renal complications
0.850 0.150 0.000
E10.6 With other specified complications
0.847 0.153 0.000
M40-M43 Deforming dorsopathies
0.846 0.154 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.845 0.155 0.000
Y44 Agents primarily affecting blood constituents
0.842 0.158 0.000
V40-V49 Car occupant injured in transport accident
0.842 0.158 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.839 0.161 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.835 0.165 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.835 0.165 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.834 0.166 0.000
M06.0 Seronegative rheumatoid arthritis
0.833 0.167 0.000
T40.4 Other synthetic narcotics
0.830 0.170 0.000
M65-M68 Disorders of synovium and tendon
0.830 0.170 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.829 0.171 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.828 0.172 0.000
M06.4 Inflammatory polyarthropathy
0.826 0.174 0.000
E20 Hypoparathyroidism
0.826 0.174 0.000
E53.8 Deficiency of other specified B group vitamins
0.825 0.175 0.000
E27.1 Primary adrenocortical insufficiency
0.824 0.176 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.821 0.179 0.000
Y44.2 Anticoagulants
0.821 0.179 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.819 0.181 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.817 0.183 0.000
W00-W19 Falls
0.815 0.185 0.000
T39.0 Salicylates
0.815 0.185 0.000
H30-H36 Disorders of choroid and retina
0.813 0.187 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.813 0.187 0.000
T39.1 4-Aminophenol derivatives
0.812 0.188 0.000
C45.9 Mesothelioma, unspecified
0.810 0.190 0.000
M06.8 Other specified rheumatoid arthritis
0.806 0.194 0.000
H02 Other disorders of eyelid
0.803 0.197 0.000
W50-W64 Exposure to animate mechanical forces
0.802 0.198 0.000
E11.4 With neurological complications
0.802 0.198 0.000
E10.0 With coma
0.801 0.199 0.000
S56 Injury of muscle and tendon at forearm level
0.801 0.199 0.000
H05 Disorders of orbit
0.799 0.201 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.797 0.203 0.000
Chapter X Diseases of the respiratory system
0.795 0.205 0.000
C78.2 Secondary malignant neoplasm of pleura
0.792 0.208 0.000
J60-J70 Lung diseases due to external agents
0.792 0.208 0.000
H04.5 Stenosis and insufficiency of lachrymal passages
0.791 0.209 0.000
J69 Pneumonitis due to solids and liquids
0.790 0.210 0.000
G61 Inflammatory polyneuropathy
0.790 0.210 0.000
J69.0 Pneumonitis due to food and vomit
0.790 0.210 0.000
H36 Retinal disorders in diseases classified elsewhere
0.789 0.211 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.789 0.211 0.000
X60-X84 Intentional self-harm
0.788 0.212 0.000
S70-S79 Injuries to the hip and thigh
0.788 0.212 0.000
G62 Other polyneuropathies
0.788 0.212 0.000
C64-C68 Malignant neoplasms of urinary tract
0.787 0.213 0.000
T00-T07 Injuries involving multiple body regions
0.786 0.213 0.000
E27.8 Other specified disorders of adrenal gland
0.785 0.215 0.000
M90 Osteopathies in diseases classified elsewhere
0.784 0.216 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.784 0.216 0.000
S20-S29 Injuries to the thorax
0.783 0.217 0.000
M05 Seropositive rheumatoid arthritis
0.783 0.217 0.000
S80-S89 Injuries to the knee and lower leg
0.782 0.218 0.000
S10-S19 Injuries to the neck
0.780 0.220 0.000
E40-E46 Malnutrition
0.780 0.220 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.779 0.221 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.778 0.222 0.000
E70-E90 Metabolic disorders
0.777 0.223 0.000
S60-S69 Injuries to the wrist and hand
0.775 0.225 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.775 0.225 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.774 0.226 0.000
M00-M03 Infectious arthropathies
0.772 0.228 0.000
M88 Paget's disease of bone [osteitis deformans]
0.772 0.228 0.000
E10.5 With peripheral circulatory complications
0.772 0.228 0.000
H36.0 Diabetic retinopathy
0.771 0.229 0.000
C50-C50 Malignant neoplasm of breast
0.771 0.229 0.000
C52 Malignant neoplasm of vagina
0.770 0.230 0.000
M86 Osteomyelitis
0.769 0.231 0.000
W20-W49 Exposure to inanimate mechanical forces
0.769 0.231 0.000
C48.2 Peritoneum, unspecified
0.768 0.232 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.768 0.232 0.000
G70-G73 Diseases of myoneural junction and muscle
0.763 0.237 0.000
M14 Arthropathies in other diseases classified elsewhere
0.763 0.237 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.762 0.238 0.000
C45.0 Mesothelioma of pleura
0.760 0.240 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.758 0.242 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.758 0.242 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.755 0.245 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.753 0.247 0.000
Y60.0 During surgical operation
0.753 0.247 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.751 0.249 0.000
X10-X19 Contact with heat and hot substances
0.751 0.249 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.751 0.249 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.751 0.249 0.000
M10 Gout
0.748 0.252 0.000
E24 Cushing's syndrome
0.748 0.252 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.745 0.255 0.000
S90-S99 Injuries to the ankle and foot
0.743 0.257 0.000
H34 Retinal vascular occlusions
0.741 0.259 0.000
M65 Synovitis and tenosynovitis
0.738 0.262 0.000
E11.6 With other specified complications
0.737 0.263 0.000
M41 Scoliosis
0.737 0.263 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.736 0.264 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.735 0.265 0.000
E23.2 Diabetes insipidus
0.735 0.265 0.000
C54.9 Corpus uteri, unspecified
0.733 0.267 0.000
E23.6 Other disorders of pituitary gland
0.733 0.267 0.000
G62.9 Polyneuropathy, unspecified
0.731 0.269 0.000
G61.0 Guillain-Barre syndrome
0.730 0.270 0.000
E20.9 Hypoparathyroidism, unspecified
0.729 0.271 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.728 0.272 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.728 0.272 0.000
W07 Fall involving chair
0.727 0.273 0.000
H04.1 Other disorders of lachrymal gland
0.726 0.273 0.000
X50-X57 Overexertion, travel and privation
0.726 0.274 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.726 0.274 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.725 0.275 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.725 0.275 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.725 0.275 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.725 0.275 0.000
C73 Malignant neoplasm of thyroid gland
0.725 0.275 0.000
T40.6 Other and unspecified narcotics
0.723 0.277 0.000
M87 Osteonecrosis
0.723 0.277 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.723 0.277 0.000
V80-V89 Other land transport accidents
0.722 0.278 0.000
C67 Malignant neoplasm of bladder
0.722 0.278 0.000
T36 Poisoning by systemic antibiotics
0.722 0.278 0.000
S81 Open wound of lower leg
0.721 0.279 0.000
C79 Secondary malignant neoplasm of other sites
0.721 0.279 0.000
E11.2 With renal complications
0.720 0.280 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.720 0.280 0.000
X20-X29 Contact with venomous animals and plants
0.719 0.281 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M06.2 Rheumatoid bursitis
0.717 0.283 0.000
M06.1 Adult-onset Still's disease
0.717 0.283 0.000
M12 Other specific arthropathies
0.717 0.283 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.717 0.283 0.000
M08 Juvenile arthritis
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.717 0.283 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.717 0.283 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.717 0.283 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.717 0.283 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.716 0.284 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.716 0.284 0.000
H02.6 Xanthelasma of eyelid
0.715 0.285 0.000
E11.8 With unspecified complications
0.714 0.285 0.000
E11.7 With multiple complications
0.714 0.285 0.000
C80 Malignant neoplasm without specification of site
0.714 0.286 0.000
C45.7 Mesothelioma of other sites
0.714 0.286 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.714 0.286 0.000
Y35-Y36 Legal intervention and operations of war
0.713 0.286 0.000
Y10-Y34 Event of undetermined intent
0.713 0.286 0.000
X85-X99 Assault
0.713 0.286 0.000
X30-X39 Exposure to forces of nature
0.713 0.286 0.000
X00-X09 Exposure to smoke, fire and flames
0.713 0.286 0.000
W75-W84 Other accidental threats to breathing
0.713 0.286 0.000
W65-W74 Accidental drowning and submersion
0.713 0.286 0.000
V98-V99 Other and unspecified transport accidents
0.713 0.286 0.000
V95-V97 Air and space transport accidents
0.713 0.286 0.000
V90-V94 Water transport accidents
0.713 0.286 0.000
V70-V79 Bus occupant injured in transport accident
0.713 0.286 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.713 0.286 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.713 0.286 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.713 0.286 0.000
V01-V09 Pedestrian injured in transport accident
0.713 0.286 0.000
E10.8 With unspecified complications
0.713 0.287 0.000
E26 Hyperaldosteronism
0.713 0.287 0.000
E28 Ovarian dysfunction
0.710 0.290 0.000
E13 Other specified diabetes mellitus
0.709 0.291 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.709 0.291 0.000
C48.0 Retroperitoneum
0.709 0.291 0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.709 0.291 0.000
T40.8 Lysergide [LSD]
0.709 0.291 0.000
T40.7 Cannabis (derivatives)
0.709 0.291 0.000
T40.5 Cocaine
0.709 0.291 0.000
T40.3 Methadone
0.709 0.291 0.000
T40.1 Heroin
0.709 0.291 0.000
T40.0 Opium
0.709 0.291 0.000
S31 Open wound of abdomen, lower back and pelvis
0.709 0.291 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.708 0.292 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.708 0.292 0.000
C58 Malignant neoplasm of placenta
0.708 0.292 0.000
H55-H59 Other disorders of eye and adnexa
0.708 0.292 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.706 0.294 0.000
H05.2 Exophthalmic conditions
0.705 0.295 0.000
T21 Burn and corrosion of trunk
0.705 0.295 0.000
M89.3 Hypertrophy of bone
0.704 0.295 0.000
S56.1 Injury of flexor muscle and tendon of other finger(s) at forearm level
0.704 0.296 0.000
C54.8 Overlapping lesion of corpus uteri
0.704 0.296 0.000
C54.3 Fundus uteri
0.704 0.296 0.000
C54.2 Myometrium
0.704 0.296 0.000
C54.0 Isthmus uteri
0.704 0.296 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.703 0.296 0.000
S70 Superficial injury of hip and thigh
0.701 0.299 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.700 0.300 0.000
S51 Open wound of forearm
0.699 0.301 0.000
Y00-Y09 Assault
0.699 0.301 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.698 0.302 0.000
M07.6 Other enteropathic arthropathies
0.698 0.302 0.000
M07.5 Arthropathy in ulcerative colitis
0.698 0.302 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.698 0.302 0.000
M07.2 Psoriatic spondylitis
0.698 0.302 0.000
M07.1 Arthritis mutilans
0.698 0.302 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.698 0.302 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.697 0.303 0.000
S20 Superficial injury of thorax
0.696 0.303 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.694 0.305 0.000
E10.7 With multiple complications
0.694 0.305 0.000
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system
0.694 0.306 0.000
C46 Kaposi's sarcoma
0.694 0.306 0.000
E34 Other endocrine disorders
0.694 0.306 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.693 0.306 0.000
Y98 Lifestyle-related condition
0.693 0.306 0.000
Y97 Environmental-pollution-related condition
0.693 0.306 0.000
Y96 Work-related condition
0.693 0.306 0.000
H04.2 Epiphora
0.691 0.309 0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)
0.690 0.309 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.690 0.310 0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.689 0.311 0.000
T31 Burns classified according to extent of body surface involved
0.689 0.311 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.688 0.311 0.000
E32 Diseases of thymus
0.688 0.311 0.000
E31 Polyglandular dysfunction
0.688 0.311 0.000
E30 Disorders of puberty, not elsewhere classified
0.688 0.311 0.000
E25 Adrenogenital disorders
0.688 0.311 0.000
E27.2 Addisonian crisis
0.687 0.313 0.000
V20-V29 Motorcycle rider injured in transport accident
0.687 0.313 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.685 0.315 0.000
T39.4 Antirheumatics, not elsewhere classified
0.685 0.315 0.000
T39.2 Pyrazolone derivatives
0.685 0.315 0.000
M07.38 Other psoriatic arthropathies (Other)
0.684 0.316 0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.684 0.316 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.684 0.316 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.684 0.316 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.684 0.316 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.684 0.316 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.684 0.316 0.000
E23.7 Disorder of pituitary gland, unspecified
0.681 0.319 0.000
Y48 Anaesthetics and therapeutic gases
0.680 0.320 0.000
W07.0 Home
0.680 0.320 0.000
E10.3 With ophthalmic complications
0.679 0.321 0.000
H02.5 Other disorders affecting eyelid function
0.679 0.321 0.000
M89.98 Disorder of bone, unspecified (Other)
0.679 0.321 0.000
T17 Foreign body in respiratory tract
0.676 0.324 0.000
M06.3 Rheumatoid nodule
0.675 0.325 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.674 0.326 0.000
J09-J18 Influenza and pneumonia
0.674 0.326 0.000
M89.6 Osteopathy after poliomyelitis
0.672 0.328 0.000
M89.5 Osteolysis
0.672 0.328 0.000
M89.4 Other hypertrophic osteo-arthropathy
0.672 0.328 0.000
M89.2 Other disorders of bone development and growth
0.672 0.328 0.000
M89.1 Epiphyseal arrest
0.672 0.328 0.000
M89.0 Algoneurodystrophy
0.672 0.328 0.000
G90-G99 Other disorders of the nervous system
0.670 0.330 0.000
S81.9 Open wound of lower leg, part unspecified
0.669 0.331 0.000
M80-M85 Disorders of bone density and structure
0.669 0.331 0.000
E10.4 With neurological complications
0.668 0.332 0.000
H34.8 Other retinal vascular occlusions
0.668 0.332 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.668 0.332 0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.667 0.333 0.000
T14 Injury of unspecified body region
0.665 0.335 0.000
W08 Fall involving other furniture
0.665 0.335 0.000
E83 Disorders of mineral metabolism
0.665 0.335 0.000
E87.6 Hypokalaemia
0.662 0.338 0.000
E55 Vitamin D deficiency
0.662 0.338 0.000
H04.9 Disorder of lachrymal system, unspecified
0.662 0.338 0.000
V49 Car occupant injured in other and unspecified transport accidents
0.661 0.338 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.661 0.339 0.000
M60-M63 Disorders of muscles
0.661 0.339 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.659 0.341 0.000
S56.7 Injury of multiple muscles and tendons at forearm level
0.659 0.341 0.000
T42.1 Iminostilbenes
0.657 0.343 0.000
T66-T78 Other and unspecified effects of external causes
0.657 0.343 0.000
V48 Car occupant injured in noncollision transport accident
0.656 0.344 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.655 0.345 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.654 0.346 0.000
E63 Other nutritional deficiencies
0.654 0.346 0.000
E56 Other vitamin deficiencies
0.654 0.346 0.000
E51 Thiamine deficiency
0.654 0.346 0.000
E50 Vitamin A deficiency
0.654 0.346 0.000
E60 Dietary zinc deficiency
0.654 0.346 0.000
E59 Dietary selenium deficiency
0.654 0.346 0.000
E58 Dietary calcium deficiency
0.654 0.346 0.000
E54 Ascorbic acid deficiency
0.654 0.346 0.000
E52 Niacin deficiency [pellagra]
0.654 0.346 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.652 0.347 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.652 0.348 0.000
M89.8 Other specified disorders of bone
0.651 0.348 0.000
C45.2 Mesothelioma of pericardium
0.651 0.349 0.000
C45.1 Mesothelioma of peritoneum
0.651 0.349 0.000
H49 Paralytic strabismus
0.651 0.349 0.000
M41.9 Scoliosis, unspecified
0.650 0.350 0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level
0.650 0.350 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.650 0.350 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.649 0.351 0.000
S92 Fracture of foot, except ankle
0.649 0.351 0.000
S20.8 Superficial injuries of other and unspecified parts of thorax
0.649 0.351 0.000
T79-T79 Certain early complications of trauma
0.649 0.351 0.000
M89.99 Disorder of bone, unspecified (Site unspecified)
0.649 0.351 0.000
M89.93 Disorder of bone, unspecified (Forearm)
0.649 0.351 0.000
M89.92 Disorder of bone, unspecified (Upper arm)
0.649 0.351 0.000
M89.91 Disorder of bone, unspecified (Shoulder region)
0.649 0.351 0.000
M89.90 Disorder of bone, unspecified (Multiple sites)
0.649 0.351 0.000
G56 Mononeuropathies of upper limb
0.648 0.352 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.647 0.353 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.647 0.353 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.647 0.353 0.000
E27.5 Adrenomedullary hyperfunction
0.646 0.354 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.646 0.354 0.000
E27.0 Other adrenocortical overactivity
0.646 0.354 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.645 0.354 0.000
H10-H13 Disorders of conjunctiva
0.645 0.354 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.644 0.356 0.000
G50 Disorders of trigeminal nerve
0.644 0.356 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.643 0.357 0.000
S36 Injury of intra-abdominal organs
0.643 0.357 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.641 0.358 0.000
V44 Car occupant injured in collision with heavy transport vehicle or bus
0.640 0.359 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.639 0.360 0.001
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.640 0.360 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.639 0.361 0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.638 0.362 0.000
T46.8 Antivaricose drugs, including sclerosing agents
0.638 0.362 0.000
T46.7 Peripheral vasodilators
0.638 0.362 0.000
T46.5 Other antihypertensive drugs, not elsewhere classified
0.638 0.362 0.000
T46.3 Coronary vasodilators, not elsewhere classified
0.638 0.362 0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.638 0.362 0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.638 0.362 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.638 0.362 0.000
M20-M25 Other joint disorders
0.637 0.363 0.000
G64 Other disorders of peripheral nervous system
0.637 0.363 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.637 0.363 0.000
S37 Injury of urinary and pelvic organs
0.637 0.363 0.000
Y64 Contaminated medical or biological substances
0.637 0.363 0.000
Y63 Failure in dosage during surgical and medical care
0.637 0.363 0.000
Y62 Failure of sterile precautions during surgical and medical care
0.637 0.363 0.000
Y61 Foreign object accidentally left in body during surgical and medical care
0.637 0.363 0.000
Y69 Unspecified misadventure during surgical and medical care
0.637 0.363 0.000
Y66 Nonadministration of surgical and medical care
0.637 0.363 0.000
G12 Spinal muscular atrophy and related syndromes
0.636 0.364 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.636 0.364 0.000
C67.5 Bladder neck
0.635 0.365 0.000
S69 Other and unspecified injuries of wrist and hand
0.634 0.366 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.634 0.366 0.000
Y60.4 During endoscopic examination
0.633 0.366 0.000
T46.1 Calcium-channel blockers
0.632 0.368 0.000
W55 Bitten or struck by other mammals
0.632 0.368 0.000
S56.4 Injury of extensor muscle and tendon of other finger(s) at forearm level
0.632 0.368 0.000
C67.9 Bladder, unspecified
0.630 0.370 0.000
W57 Bitten or stung by non-venomous insect and other non-venomous arthropods
0.630 0.370 0.000
T18 Foreign body in alimentary tract
0.630 0.370 0.000
T16 Foreign body in ear
0.629 0.370 0.000
W13 Fall from, out of or through building or structure
0.629 0.371 0.000
G11 Hereditary ataxia
0.629 0.371 0.000
T25 Burn and corrosion of ankle and foot
0.628 0.372 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.627 0.373 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.627 0.373 0.000
C09 Malignant neoplasm of tonsil
0.627 0.373 0.000
M11 Other crystal arthropathies
0.626 0.374 0.000
Y46.2 Hydantoin derivatives
0.625 0.375 0.000
C48.8 Overlapping lesion of retroperitoneum and peritoneum
0.625 0.375 0.000
C48.1 Specified parts of peritoneum
0.625 0.375 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.625 0.375 0.000
Y59 Other and unspecified vaccines and biological substances
0.625 0.375 0.000
Y58 Bacterial vaccines
0.625 0.375 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.625 0.375 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.625 0.375 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.625 0.375 0.000
S54 Injury of nerves at forearm level
0.624 0.375 0.000
M88.9 Paget's disease of bone, unspecified
0.623 0.377 0.000
T42.4 Benzodiazepines
0.623 0.377 0.000
G30-G32 Other degenerative diseases of the nervous system
0.623 0.377 0.000
M50-M54 Other dorsopathies
0.622 0.378 0.000
Y43 Primarily systemic agents
0.622 0.378 0.000
E46 Unspecified protein-energy malnutrition
0.622 0.378 0.000
V43 Car occupant injured in collision with car, pick-up truck or van
0.621 0.379 0.000
E83.4 Disorders of magnesium metabolism
0.621 0.379 0.000
S22.3 Fracture of rib
0.620 0.380 0.000
M86.9 Osteomyelitis, unspecified
0.619 0.381 0.000
S59 Other and unspecified injuries of forearm
0.619 0.381 0.000
S58 Traumatic amputation of forearm
0.619 0.381 0.000
S57 Crushing injury of forearm
0.619 0.381 0.000
S55 Injury of blood vessels at forearm level
0.619 0.381 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.619 0.381 0.000
E53.9 Vitamin B deficiency, unspecified
0.617 0.383 0.000
E53.1 Pyridoxine deficiency
0.617 0.383 0.000
E53.0 Riboflavin deficiency
0.617 0.383 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.617 0.383 0.000
E11.0 With coma
0.617 0.383 0.000
S50 Superficial injury of forearm
0.617 0.383 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.616 0.384 0.000
Y65 Other misadventures during surgical and medical care
0.616 0.384 0.000
X78 Intentional self-harm by sharp object
0.615 0.384 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.615 0.385 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.615 0.385 0.000
E23.1 Drug-induced hypopituitarism
0.615 0.385 0.000
M90.7 Fracture of bone in neoplastic disease
0.615 0.385 0.000
H04.6 Other changes in lachrymal passages
0.615 0.385 0.000
H04.4 Chronic inflammation of lachrymal passages
0.615 0.385 0.000
H04.0 Dacryoadenitis
0.615 0.385 0.000
C50 Malignant neoplasm of breast
0.615 0.385 0.000
T47.1 Other antacids and anti-gastric-secretion drugs
0.614 0.386 0.000
Y57 Other and unspecified drugs and medicaments
0.614 0.386 0.000
M25 Other joint disorders, not elsewhere classified
0.614 0.386 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.612 0.388 0.000
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified
0.611 0.389 0.000
H02.3 Blepharochalasis
0.610 0.390 0.000
G63.2 Diabetic polyneuropathy
0.609 0.391 0.000
M00 Pyogenic arthritis
0.608 0.392 0.000
C80.9 Malignant neoplasm, unspecified
0.608 0.392 0.000
G60 Hereditary and idiopathic neuropathy
0.607 0.392 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.608 0.392 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.607 0.393 0.000
T23 Burn and corrosion of wrist and hand
0.607 0.393 0.000
H05.8 Other disorders of orbit
0.607 0.393 0.000
S22.30 Fracture of rib (closed)
0.607 0.393 0.000
S66.8 Injury of other muscles and tendons at wrist and hand level
0.606 0.393 0.000
M42 Spinal osteochondrosis
0.606 0.394 0.000
M40 Kyphosis and lordosis
0.606 0.394 0.000
W15 Fall from cliff
0.605 0.394 0.000
E27.9 Disorder of adrenal gland, unspecified
0.605 0.394 0.000
C51 Malignant neoplasm of vulva
0.605 0.395 0.000
T59 Toxic effect of other gases, fumes and vapours
0.605 0.395 0.000
T13 Other injuries of lower limb, level unspecified
0.604 0.396 0.000
T22.3 Burn of third degree of shoulder and upper limb, except wrist and hand
0.604 0.396 0.000
Y44.9 Other and unspecified agents affecting blood constituents
0.604 0.396 0.000
Y44.7 Plasma substitutes
0.604 0.396 0.000
Y44.6 Natural blood and blood products
0.604 0.396 0.000
Y44.5 Thrombolytic drugs
0.604 0.396 0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]
0.604 0.396 0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants
0.604 0.396 0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations
0.604 0.396 0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations
0.604 0.396 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.604 0.396 0.000
V47 Car occupant injured in collision with fixed or stationary object
0.603 0.396 0.000
V46 Car occupant injured in collision with other nonmotor vehicle
0.603 0.396 0.000
V45 Car occupant injured in collision with railway train or railway vehicle
0.603 0.396 0.000
V42 Car occupant injured in collision with two- or three-wheeled motor vehicle
0.603 0.396 0.000
V41 Car occupant injured in collision with pedal cycle
0.603 0.396 0.000
V40 Car occupant injured in collision with pedestrian or animal
0.603 0.396 0.000
H06.2 Dysthyroid exophthalmos
0.603 0.397 0.000
T20 Burn and corrosion of head and neck
0.602 0.398 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.602 0.398 0.000
M90.1 Periostitis in other infectious diseases classified elsewhere
0.602 0.398 0.000
M43 Other deforming dorsopathies
0.602 0.398 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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