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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs34034473
log Bayes Factor = 13.1796
Chromosome 19   position 58,132,106  (GRCh37) Explore rs34034473 on Ensembl!
Variant rs34034473 is part of Cluster X0278

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
M45-M49 Spondylopathies
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
0.999 0.001 0.000
M47 Spondylosis
0.999 0.001 0.000
E70-E90 Metabolic disorders
0.998 0.002 0.000
Chapter VI Diseases of the nervous system
0.998 0.002 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.996 0.004 0.000
M47.8 Other spondylosis
0.996 0.004 0.000
H30-H36 Disorders of choroid and retina
0.993 0.007 0.000
Chapter VIII Diseases of the ear and mastoid process
0.993 0.007 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.992 0.008 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.992 0.008 0.000
Chapter II Neoplasms
0.992 0.008 0.000
G90-G99 Other disorders of the nervous system
0.991 0.009 0.000
H36 Retinal disorders in diseases classified elsewhere
0.990 0.010 0.000
E10 Insulin-dependent diabetes mellitus
0.990 0.010 0.000
M47.82 Other spondylosis (Cervical region)
0.990 0.010 0.000
H36.0 Diabetic retinopathy
0.989 0.011 0.000
E14 Unspecified diabetes mellitus
0.988 0.012 0.000
E83 Disorders of mineral metabolism
0.987 0.013 0.000
E87.2 Acidosis
0.985 0.015 0.000
C50-C50 Malignant neoplasm of breast
0.977 0.023 0.000
Chapter XX External causes of morbidity and mortality
0.973 0.027 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.972 0.028 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.970 0.030 0.000
C50 Malignant neoplasm of breast
0.967 0.033 0.000
C92 Myeloid leukaemia
0.964 0.036 0.000
G20-G26 Extrapyramidal and movement disorders
0.962 0.038 0.000
M48 Other spondylopathies
0.954 0.046 0.000
E83.4 Disorders of magnesium metabolism
0.952 0.048 0.000
G95 Other diseases of spinal cord
0.950 0.050 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.949 0.051 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.947 0.053 0.000
C50.9 Breast, unspecified
0.944 0.056 0.000
E14.3 With ophthalmic complications
0.942 0.058 0.000
H90-H95 Other disorders of ear
0.940 0.060 0.000
M40-M43 Deforming dorsopathies
0.937 0.063 0.000
E10.3 With ophthalmic complications
0.932 0.068 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.931 0.069 0.000
H65-H75 Diseases of middle ear and mastoid
0.929 0.071 0.000
C92.1 Chronic myeloid leukaemia
0.927 0.073 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.920 0.080 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.919 0.081 0.000
E11 Non-insulin-dependent diabetes mellitus
0.916 0.084 0.000
C50.3 Lower-inner quadrant of breast
0.914 0.086 0.000
E14.9 Without complications
0.910 0.090 0.000
C91 Lymphoid leukaemia
0.910 0.090 0.000
H50 Other strabismus
0.908 0.092 0.000
E11.3 With ophthalmic complications
0.902 0.098 0.000
Q60-Q64 Congenital malformations of the urinary system
0.901 0.099 0.000
M41 Scoliosis
0.900 0.100 0.000
G20 Parkinson's disease
0.899 0.101 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.899 0.101 0.000
G95.2 Cord compression, unspecified
0.898 0.102 0.000
M86-M90 Other osteopathies
0.896 0.104 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.895 0.105 0.000
H50.9 Strabismus, unspecified
0.882 0.118 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.882 0.118 0.000
H90 Conductive and sensorineural hearing loss
0.881 0.119 0.000
G24 Dystonia
0.881 0.119 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.880 0.120 0.000
E83.3 Disorders of phosphorus metabolism
0.879 0.121 0.000
E10.1 With ketoacidosis
0.878 0.121 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.878 0.122 0.000
G90 Disorders of autonomic nervous system
0.877 0.123 0.000
E87.3 Alkalosis
0.875 0.125 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.875 0.125 0.000
Q21 Congenital malformations of cardiac septa
0.874 0.126 0.000
M41.9 Scoliosis, unspecified
0.873 0.127 0.000
H55-H59 Other disorders of eye and adnexa
0.872 0.128 0.000
M65-M68 Disorders of synovium and tendon
0.870 0.130 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.869 0.131 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.868 0.132 0.000
M47.2 Other spondylosis with radiculopathy
0.867 0.133 0.000
Chapter V Mental and behavioural disorders
0.866 0.134 0.000
E10.9 Without complications
0.865 0.135 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.863 0.137 0.000
Chapter X Diseases of the respiratory system
0.862 0.138 0.000
E87.7 Fluid overload
0.861 0.139 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.856 0.144 0.000
R26 Abnormalities of gait and mobility
0.854 0.146 0.000
F30-F39 Mood [affective] disorders
0.853 0.147 0.000
J09-J18 Influenza and pneumonia
0.850 0.150 0.000
V10-V19 Pedal cyclist injured in transport accident
0.850 0.150 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.846 0.154 0.000
M48.0 Spinal stenosis
0.842 0.158 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.842 0.158 0.000
Q61 Cystic kidney disease
0.840 0.160 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.839 0.161 0.000
H93 Other disorders of ear, not elsewhere classified
0.839 0.161 0.000
M47.9 Spondylosis, unspecified
0.838 0.162 0.000
X50-X57 Overexertion, travel and privation
0.836 0.164 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.835 0.165 0.000
M41.96 Scoliosis, unspecified (Lumbar region)
0.834 0.166 0.000
G96 Other disorders of central nervous system
0.832 0.168 0.000
Q50-Q56 Congenital malformations of genital organs
0.831 0.169 0.000
Q21.1 Atrial septal defect
0.829 0.171 0.000
F31 Bipolar affective disorder
0.827 0.173 0.000
Chapter XIV Diseases of the genitourinary system
0.825 0.175 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.824 0.176 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.822 0.178 0.000
J18 Pneumonia, organism unspecified
0.821 0.179 0.000
M47.1 Other spondylosis with myelopathy
0.820 0.180 0.000
C50.0 Nipple and areola
0.819 0.181 0.000
H52 Disorders of refraction and accommodation
0.816 0.184 0.000
W20-W49 Exposure to inanimate mechanical forces
0.815 0.185 0.000
E85 Amyloidosis
0.814 0.186 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.813 0.187 0.000
M91-M94 Chondropathies
0.812 0.188 0.000
H33 Retinal detachments and breaks
0.812 0.188 0.000
H60-H62 Diseases of external ear
0.811 0.189 0.000
H55 Nystagmus and other irregular eye movements
0.810 0.190 0.000
J18.1 Lobar pneumonia, unspecified
0.810 0.190 0.000
V40-V49 Car occupant injured in transport accident
0.810 0.190 0.000
E87.5 Hyperkalaemia
0.807 0.193 0.000
E83.5 Disorders of calcium metabolism
0.806 0.194 0.000
C91.1 Chronic lymphocytic leukaemia
0.805 0.195 0.000
E10.5 With peripheral circulatory complications
0.805 0.195 0.000
Chapter I Certain infectious and parasitic diseases
0.805 0.195 0.000
H20 Iridocyclitis
0.804 0.196 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.803 0.197 0.000
H49 Paralytic strabismus
0.802 0.198 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.800 0.200 0.000
E11.2 With renal complications
0.800 0.200 0.000
Y43 Primarily systemic agents
0.800 0.200 0.000
M46 Other inflammatory spondylopathies
0.800 0.200 0.000
H80-H83 Diseases of inner ear
0.800 0.200 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.800 0.200 0.000
E13 Other specified diabetes mellitus
0.799 0.201 0.000
N17-N19 Renal failure
0.798 0.202 0.000
E65-E68 Obesity and other hyperalimentation
0.797 0.203 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.797 0.203 0.000
H15 Disorders of sclera
0.797 0.203 0.000
H18 Other disorders of cornea
0.796 0.204 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.794 0.206 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.794 0.206 0.000
C92.7 Other myeloid leukaemia
0.789 0.211 0.000
H90.2 Conductive hearing loss, unspecified
0.789 0.211 0.000
F33 Recurrent depressive disorder
0.789 0.211 0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.789 0.211 0.000
J00-J06 Acute upper respiratory infections
0.787 0.213 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.787 0.213 0.000
M87 Osteonecrosis
0.787 0.213 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.787 0.213 0.000
E14.1 With ketoacidosis
0.786 0.214 0.000
N17 Acute renal failure
0.783 0.217 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.781 0.219 0.000
M49 Spondylopathies in diseases classified elsewhere
0.780 0.220 0.000
V98-V99 Other and unspecified transport accidents
0.779 0.221 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.779 0.221 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.778 0.222 0.000
G95.9 Disease of spinal cord, unspecified
0.778 0.222 0.000
E84 Cystic fibrosis
0.777 0.223 0.000
H65 Nonsuppurative otitis media
0.777 0.223 0.000
H50.5 Heterophoria
0.776 0.224 0.000
G51 Facial nerve disorders
0.775 0.225 0.000
G24.5 Blepharospasm
0.775 0.225 0.000
H72 Perforation of tympanic membrane
0.772 0.228 0.000
V80-V89 Other land transport accidents
0.772 0.228 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.772 0.228 0.000
N17.9 Acute renal failure, unspecified
0.771 0.229 0.000
C82.2 Large cell, follicular
0.769 0.231 0.000
C45 Mesothelioma
0.768 0.231 0.000
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)
0.768 0.232 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.766 0.234 0.000
M48.00 Spinal stenosis (Multiple sites in spine)
0.765 0.235 0.000
M48.02 Spinal stenosis (Cervical region)
0.764 0.236 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.764 0.236 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.763 0.237 0.000
X00-X09 Exposure to smoke, fire and flames
0.763 0.237 0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified
0.761 0.239 0.000
E10.0 With coma
0.760 0.239 0.000
N60-N64 Disorders of breast
0.761 0.239 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.760 0.240 0.000
R41.3 Other amnesia
0.760 0.240 0.000
C95 Leukaemia of unspecified cell type
0.759 0.241 0.000
H66 Suppurative and unspecified otitis media
0.757 0.243 0.000
R74 Abnormal serum enzyme levels
0.757 0.243 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.757 0.243 0.000
C81 Hodgkin's disease
0.756 0.244 0.000
C84.4 Peripheral T-cell lymphoma
0.755 0.245 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.755 0.245 0.000
C82.3 Follicular lymphoma grade IIIa
0.753 0.247 0.000
H21 Other disorders of iris and ciliary body
0.753 0.247 0.000
E10.6 With other specified complications
0.750 0.250 0.000
M00-M03 Infectious arthropathies
0.750 0.250 0.000
R27 Other lack of coordination
0.748 0.252 0.000
Q61.3 Polycystic kidney, unspecified
0.747 0.253 0.000
Y49.2 Other and unspecified antidepressants
0.746 0.254 0.000
H93.1 Tinnitus
0.745 0.255 0.000
M47.84 Other spondylosis (Thoracic region)
0.745 0.255 0.000
G24.9 Dystonia, unspecified
0.745 0.255 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.744 0.255 0.000
C93 Monocytic leukaemia
0.744 0.256 0.000
H90.0 Conductive hearing loss, bilateral
0.743 0.257 0.000
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)
0.743 0.257 0.000
M47.22 Other spondylosis with radiculopathy (Cervical region)
0.742 0.258 0.000
C91.0 Acute lymphoblastic leukaemia
0.741 0.259 0.000
C50.6 Axillary tail of breast
0.741 0.259 0.000
Y52 Agents primarily affecting the cardiovascular system
0.741 0.259 0.000
E11.0 With coma
0.740 0.260 0.000
H52.3 Anisometropia and aniseikonia
0.740 0.260 0.000
H53-H54 Visual disturbances and blindness
0.740 0.260 0.000
C50.8 Overlapping lesion of breast
0.739 0.261 0.000
C49.3 Connective and soft tissue of thorax
0.739 0.261 0.000
F31.9 Bipolar affective disorder, unspecified
0.733 0.267 0.000
H69 Other disorders of Eustachian tube
0.733 0.267 0.000
R41.0 Disorientation, unspecified
0.732 0.268 0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest
0.732 0.268 0.000
C92.0 Acute myeloid leukaemia
0.731 0.269 0.000
E65 Localised adiposity
0.731 0.269 0.000
M60-M63 Disorders of muscles
0.731 0.269 0.000
M67 Other disorders of synovium and tendon
0.731 0.269 0.000
E14.4 With neurological complications
0.729 0.270 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.729 0.271 0.000
Q25 Congenital malformations of great arteries
0.729 0.271 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.729 0.271 0.000
H33.2 Serous retinal detachment
0.728 0.272 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.727 0.273 0.000
N00-N08 Glomerular diseases
0.727 0.273 0.000
E83.1 Disorders of iron metabolism
0.726 0.274 0.000
H30 Chorioretinal inflammation
0.723 0.277 0.000
V17 Pedal cyclist injured in collision with fixed or stationary object
0.723 0.277 0.000
G95.1 Vascular myelopathies
0.722 0.278 0.000
C32 Malignant neoplasm of larynx
0.721 0.279 0.000
H92 Otalgia and effusion of ear
0.720 0.279 0.000
E10.2 With renal complications
0.720 0.280 0.000
Y00-Y09 Assault
0.720 0.280 0.000
E74 Other disorders of carbohydrate metabolism
0.719 0.281 0.000
Q61.2 Polycystic kidney, adult type
0.719 0.281 0.000
M89 Other disorders of bone
0.719 0.281 0.000
G51.0 Bell's palsy
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
H60 Otitis externa
0.717 0.283 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.716 0.284 0.000
E79 Disorders of purine and pyrimidine metabolism
0.716 0.284 0.000
E77 Disorders of glycoprotein metabolism
0.716 0.284 0.000
E76 Disorders of glycosaminoglycan metabolism
0.716 0.284 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.716 0.284 0.000
E72 Other disorders of amino-acid metabolism
0.716 0.284 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.716 0.284 0.000
E70 Disorders of aromatic amino-acid metabolism
0.716 0.284 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.716 0.284 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.714 0.286 0.000
Q35-Q37 Cleft lip and cleft palate
0.714 0.286 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.714 0.286 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.714 0.286 0.000
M47.85 Other spondylosis (Thoracolumbar region)
0.714 0.286 0.000
M47.83 Other spondylosis (Cervicothoracic region)
0.714 0.286 0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.714 0.286 0.000
G54 Nerve root and plexus disorders
0.712 0.288 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.712 0.288 0.000
C84.5 Other and unspecified T-cell lymphomas
0.712 0.288 0.000
H71 Cholesteatoma of middle ear
0.712 0.288 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.712 0.288 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.711 0.288 0.000
C94 Other leukaemias of specified cell type
0.711 0.288 0.000
C86 Other specified types of T/NK-cell lymphoma
0.711 0.288 0.000
E87.4 Mixed disorder of acid-base balance
0.711 0.289 0.000
G90.9 Disorder of autonomic nervous system, unspecified
0.711 0.289 0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics
0.711 0.289 0.000
J17 Pneumonia in diseases classified elsewhere
0.711 0.289 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.710 0.290 0.000
G92 Toxic encephalopathy
0.710 0.290 0.000
H18.2 Other corneal oedema
0.710 0.290 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.710 0.290 0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)
0.710 0.290 0.000
E10.7 With multiple complications
0.710 0.290 0.000
G61 Inflammatory polyneuropathy
0.710 0.290 0.000
C88 Malignant immunoproliferative diseases
0.709 0.291 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.709 0.291 0.000
G90.3 Multisystem degeneration
0.709 0.291 0.000
E14.8 With unspecified complications
0.708 0.292 0.000
E14.7 With multiple complications
0.708 0.292 0.000
E14.6 With other specified complications
0.708 0.292 0.000
E14.5 With peripheral circulatory complications
0.708 0.292 0.000
E14.2 Withrenal complications
0.708 0.292 0.000
E14.0 With coma
0.708 0.292 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.708 0.292 0.000
E83.8 Other disorders of mineral metabolism
0.708 0.292 0.000
E83.2 Disorders of zinc metabolism
0.708 0.292 0.000
E83.0 Disorders of copper metabolism
0.708 0.292 0.000
C51-C58 Malignant neoplasms of female genital organs
0.708 0.292 0.000
V48 Car occupant injured in noncollision transport accident
0.707 0.292 0.000
N63 Unspecified lump in breast
0.707 0.293 0.000
M93 Other osteochondropathies
0.706 0.294 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.705 0.295 0.000
M41.94 Scoliosis, unspecified (Thoracic region)
0.704 0.295 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.702 0.298 0.000
C82.1 Mixed small cleaved and large cell, follicular
0.702 0.298 0.000
J00 Acute nasopharyngitis [common cold]
0.701 0.299 0.000
C49.5 Connective and soft tissue of pelvis
0.701 0.299 0.000
C50.5 Lower-outer quadrant of breast
0.700 0.300 0.000
G70-G73 Diseases of myoneural junction and muscle
0.700 0.300 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.698 0.302 0.000
R74.8 Abnormal levels of other serum enzymes
0.698 0.302 0.000
X20-X29 Contact with venomous animals and plants
0.698 0.302 0.000
Y35-Y36 Legal intervention and operations of war
0.698 0.302 0.000
Y10-Y34 Event of undetermined intent
0.698 0.302 0.000
X85-X99 Assault
0.698 0.302 0.000
X30-X39 Exposure to forces of nature
0.698 0.302 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.698 0.302 0.000
W75-W84 Other accidental threats to breathing
0.698 0.302 0.000
W65-W74 Accidental drowning and submersion
0.698 0.302 0.000
V95-V97 Air and space transport accidents
0.698 0.302 0.000
V90-V94 Water transport accidents
0.698 0.302 0.000
V70-V79 Bus occupant injured in transport accident
0.698 0.302 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.698 0.302 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.698 0.302 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.698 0.302 0.000
V01-V09 Pedestrian injured in transport accident
0.698 0.302 0.000
H90.5 Sensorineural hearing loss, unspecified
0.697 0.303 0.000
X10-X19 Contact with heat and hot substances
0.697 0.303 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.697 0.303 0.000
Q44.6 Cystic disease of liver
0.696 0.304 0.000
W50-W64 Exposure to animate mechanical forces
0.695 0.304 0.000
H51 Other disorders of binocular movement
0.695 0.305 0.000
G96.0 Cerebrospinal fluid leak
0.695 0.305 0.000
Q21.0 Ventricular septal defect
0.694 0.306 0.000
J14 Pneumonia due to Haemophilus influenzae
0.693 0.307 0.000
X51 Travel and motion
0.692 0.308 0.000
M47.12 Other spondylosis with myelopathy (Cervical region)
0.692 0.308 0.000
C92.9 Myeloid leukaemia, unspecified
0.691 0.309 0.000
C92.8 Acute myeloid leukaemia with multilineage dysplasia
0.691 0.309 0.000
C92.6 Acute myeloid leukaemia with 11q23-abnormality
0.691 0.309 0.000
C92.5 Acute myelomonocytic leukaemia
0.691 0.309 0.000
C92.4 Acute promyelocytic leukaemia
0.691 0.309 0.000
C92.3 Myeloid sarcoma
0.691 0.309 0.000
C92.2 Subacute myeloid leukaemia
0.691 0.309 0.000
G62 Other polyneuropathies
0.691 0.309 0.000
W44 Foreign body entering into or through eye or natural orifice
0.691 0.309 0.000
Y44 Agents primarily affecting blood constituents
0.690 0.310 0.000
B99-B99 Other infectious diseases
0.690 0.310 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.690 0.310 0.000
H33.0 Retinal detachment with retinal break
0.690 0.310 0.000
G60 Hereditary and idiopathic neuropathy
0.690 0.310 0.000
G23 Other degenerative diseases of basal ganglia
0.689 0.311 0.000
G21 Secondary Parkinsonism
0.689 0.311 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.689 0.311 0.000
G22 Parkinsonism in diseases classified elsewhere
0.689 0.311 0.000
G90.2 Horner's syndrome
0.689 0.311 0.000
N19 Unspecified renal failure
0.689 0.311 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.688 0.312 0.000
M65 Synovitis and tenosynovitis
0.688 0.312 0.000
H04 Disorders of lachrymal system
0.687 0.313 0.000
Q51 Congenital malformations of uterus and cervix
0.687 0.313 0.000
G91 Hydrocephalus
0.686 0.313 0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)
0.686 0.314 0.000
C91.4 Hairy-cell leukaemia
0.686 0.314 0.000
M05-M14 Inflammatory polyarthropathies
0.685 0.315 0.000
Q27 Other congenital malformations of peripheral vascular system
0.684 0.315 0.000
H16 Keratitis
0.684 0.316 0.000
M48.04 Spinal stenosis (Thoracic region)
0.684 0.316 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.684 0.316 0.000
M48.9 Spondylopathy, unspecified
0.684 0.316 0.000
M48.8 Other specified spondylopathies
0.684 0.316 0.000
M48.4 Fatigue fracture of vertebra
0.684 0.316 0.000
M48.3 Traumatic spondylopathy
0.684 0.316 0.000
M48.2 Kissing spine
0.684 0.316 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.684 0.316 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.684 0.316 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.683 0.317 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.682 0.318 0.000
M87.9 Osteonecrosis, unspecified
0.682 0.318 0.000
Q76 Congenital malformations of spine and bony thorax
0.681 0.318 0.000
Q00-Q07 Congenital malformations of the nervous system
0.681 0.318 0.000
J02 Acute pharyngitis
0.681 0.319 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.680 0.319 0.000
A30-A49 Other bacterial diseases
0.680 0.320 0.000
G95.8 Other specified diseases of spinal cord
0.680 0.320 0.000
G95.0 Syringomyelia and syringobulbia
0.680 0.320 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.680 0.320 0.000
H57 Other disorders of eye and adnexa
0.679 0.321 0.000
N99-N99 Other disorders of the genitourinary system
0.679 0.321 0.000
C82.6 Cutaneous follicle centre lymphoma
0.679 0.321 0.000
C82.5 Diffuse follicle centre lymphoma
0.679 0.321 0.000
C82.4 Follicular lymphoma grade IIIb
0.679 0.321 0.000
Y43.0 Antiallergic and antiemetic drugs
0.679 0.321 0.000
M86 Osteomyelitis
0.679 0.321 0.000
Q63 Other congenital malformations of kidney
0.679 0.321 0.000
Q66 Congenital deformities of feet
0.678 0.322 0.000
H65.4 Other chronic nonsuppurative otitis media
0.678 0.322 0.000
H50.4 Other and unspecified heterotropia
0.677 0.323 0.000
Q80-Q89 Other congenital malformations
0.677 0.323 0.000
R26.2 Difficulty in walking, not elsewhere classified
0.675 0.325 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.674 0.326 0.000
X50 Overexertion and strenuous or repetitive movements
0.674 0.326 0.000
G51.8 Other disorders of facial nerve
0.674 0.326 0.000
M70-M79 Other soft tissue disorders
0.673 0.327 0.000
M40 Kyphosis and lordosis
0.673 0.327 0.000
M42 Spinal osteochondrosis
0.672 0.328 0.000
Chapter XXII Codes for special purposes
0.671 0.329 0.000
N10-N16 Renal tubulo-interstitial diseases
0.671 0.329 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.671 0.329 0.000
C82.0 Small cleaved cell, follicular
0.670 0.330 0.000
C49.9 Connective and soft tissue, unspecified
0.670 0.330 0.000
M46.0 Spinal enthesopathy
0.669 0.331 0.000
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system
0.667 0.332 0.000
C46 Kaposi's sarcoma
0.667 0.332 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.666 0.334 0.000
H68 Eustachian salpingitis and obstruction
0.666 0.334 0.000
H67 Otitis media in diseases classified elsewhere
0.666 0.334 0.000
F39 Unspecified mood [affective] disorder
0.666 0.334 0.000
H73 Other disorders of tympanic membrane
0.665 0.335 0.000
H93.3 Disorders of acoustic nerve
0.664 0.336 0.000
Y48 Anaesthetics and therapeutic gases
0.664 0.336 0.000
M67.2 Synovial hypertrophy, not elsewhere classified
0.663 0.337 0.000
R76 Other abnormal immunological findings in serum
0.663 0.337 0.000
H04.1 Other disorders of lachrymal gland
0.663 0.337 0.000
E87.0 Hyperosmolality and hypernatraemia
0.662 0.338 0.000
N64 Other disorders of breast
0.662 0.338 0.000
R94 Abnormal results of function studies
0.662 0.338 0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral
0.661 0.339 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.661 0.339 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.661 0.339 0.000
H53 Visual disturbances
0.661 0.339 0.000
G99.8 Other specified disorders of nervous system in diseases classified elsewhere
0.659 0.340 0.000
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere
0.659 0.340 0.000
Q26 Congenital malformations of great veins
0.659 0.341 0.000
Q22 Congenital malformations of pulmonary and tricuspid valves
0.659 0.341 0.000
Q20 Congenital malformations of cardiac chambers and connexions
0.659 0.341 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.659 0.341 0.000
E10.8 With unspecified complications
0.659 0.341 0.000
E50-E64 Other nutritional deficiencies
0.658 0.341 0.000
B50-B64 Protozoal diseases
0.658 0.342 0.000
Q55 Other congenital malformations of male genital organs
0.658 0.342 0.000
H15.8 Other disorders of sclera
0.658 0.342 0.000
Q12 Congenital lens malformations
0.658 0.342 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.658 0.342 0.000
H52.0 Hypermetropia
0.658 0.342 0.000
Y43.3 Other antineoplastic drugs
0.658 0.342 0.000
E11.7 With multiple complications
0.657 0.343 0.000
C32.0 Glottis
0.657 0.343 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.656 0.344 0.000
H49.2 Sixth [abducent] nerve palsy
0.656 0.344 0.000
E13.9 Without complications
0.654 0.345 0.000
R71 Abnormality of red blood cells
0.654 0.346 0.000
F30 Manic episode
0.653 0.347 0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.653 0.347 0.000
Q61.9 Cystic kidney disease, unspecified
0.653 0.347 0.000
N17.1 Acute renal failure with acute cortical necrosis
0.653 0.347 0.000
H70 Mastoiditis and related conditions
0.653 0.347 0.000
M41.8 Other forms of scoliosis
0.653 0.347 0.000
C91.9 Lymphoid leukaemia, unspecified
0.652 0.348 0.000
C91.8 Mature B-cell leukaemia Burkitt-type
0.652 0.348 0.000
C91.7 Other lymphoid leukaemia
0.652 0.348 0.000
C91.6 Prolymphocytic leukaemia of T-cell type
0.652 0.348 0.000
C91.5 Adult T-cell leukaemia
0.652 0.348 0.000
C91.3 Prolymphocytic leukaemia
0.652 0.348 0.000
C91.2 Subacute lymphocytic leukaemia
0.652 0.348 0.000
H50.8 Other specified strabismus
0.651 0.349 0.000
H50.6 Mechanical strabismus
0.651 0.349 0.000
H50.3 Intermittent heterotropia
0.651 0.349 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.651 0.349 0.000
E16 Other disorders of pancreatic internal secretion
0.651 0.349 0.000
C50.2 Upper-inner quadrant of breast
0.651 0.349 0.000
F34 Persistent mood [affective] disorders
0.650 0.350 0.000
M88 Paget's disease of bone [osteitis deformans]
0.650 0.350 0.000
H50.2 Vertical strabismus
0.648 0.352 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.648 0.352 0.000
M66 Spontaneous rupture of synovium and tendon
0.647 0.352 0.000
H20.8 Other iridocyclitis
0.647 0.353 0.000
R47-R49 Symptoms and signs involving speech and voice
0.647 0.353 0.000
H81 Disorders of vestibular function
0.647 0.353 0.000
H90.3 Sensorineural hearing loss, bilateral
0.646 0.354 0.000
Q64 Other congenital malformations of urinary system
0.646 0.354 0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.646 0.354 0.000
M41.5 Other secondary scoliosis
0.645 0.355 0.000
M41.4 Neuromuscular scoliosis
0.645 0.355 0.000
M41.3 Thoracogenic scoliosis
0.645 0.355 0.000
M41.2 Other idiopathic scoliosis
0.645 0.355 0.000
M41.1 Juvenile idiopathic scoliosis
0.645 0.355 0.000
M41.0 Infantile idiopathic scoliosis
0.645 0.355 0.000
Q78 Other osteochondrodysplasias
0.644 0.355 0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine
0.644 0.355 0.000
Q75 Other congenital malformations of skull and face bones
0.644 0.355 0.000
Q74 Other congenital malformations of limb(s)
0.644 0.355 0.000
Q73 Reduction defects of unspecified limb
0.644 0.355 0.000
Q72 Reduction defects of lower limb
0.644 0.355 0.000
Q71 Reduction defects of upper limb
0.644 0.355 0.000
Q70 Syndactyly
0.644 0.355 0.000
Q69 Polydactyly
0.644 0.355 0.000
Q68 Other congenital musculoskeletal deformities
0.644 0.355 0.000
G54.9 Nerve root and plexus disorder, unspecified
0.644 0.356 0.000
R78 Findings of drugs and other substances, not normally found in blood
0.644 0.356 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.643 0.357 0.000
H35 Other retinal disorders
0.643 0.357 0.000
Q79.8 Other congenital malformations of musculoskeletal system
0.642 0.358 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.642 0.358 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.641 0.358 0.000
W49 Exposure to other and unspecified inanimate mechanical forces
0.641 0.359 0.000
G90.0 Idiopathic peripheral autonomic neuropathy
0.641 0.359 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.641 0.359 0.000
E85.3 Secondary systemic amyloidosis
0.640 0.360 0.000
V99 Unspecified transport accident
0.640 0.360 0.000
R46 Symptoms and signs involving appearance and behaviour
0.640 0.360 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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