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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs34574480
log Bayes Factor = 13.3586
Chromosome 12   position 115,307,567  (GRCh37) Explore rs34574480 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
0.999 0.001 0.000
Chapter VI Diseases of the nervous system
0.999 0.001 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.998 0.002 0.000
I25.1 Atherosclerotic heart disease
0.998 0.002 0.000
Chapter V Mental and behavioural disorders
0.997 0.003 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.995 0.005 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.990 0.010 0.000
Z50 Care involving use of rehabilitation procedures
0.984 0.016 0.000
Chapter XXI Factors influencing health status and contact with health services
0.983 0.017 0.000
M20-M25 Other joint disorders
0.982 0.018 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.981 0.019 0.000
F30-F39 Mood [affective] disorders
0.980 0.020 0.000
G40-G47 Episodic and paroxysmal disorders
0.978 0.022 0.000
Z50.1 Other physical therapy
0.969 0.031 0.000
M23 Internal derangement of knee
0.965 0.035 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.964 0.036 0.000
E70-E90 Metabolic disorders
0.963 0.037 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.963 0.037 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.954 0.046 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.954 0.046 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.952 0.048 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.948 0.052 0.000
G20-G26 Extrapyramidal and movement disorders
0.944 0.056 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.943 0.057 0.000
N17-N19 Renal failure
0.940 0.060 0.000
M05-M14 Inflammatory polyarthropathies
0.940 0.060 0.000
I25.2 Old myocardial infarction
0.938 0.062 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.937 0.063 0.000
E78.0 Pure hypercholesterolaemia
0.927 0.073 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.925 0.075 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.924 0.076 0.000
F31 Bipolar affective disorder
0.921 0.079 0.000
M65-M68 Disorders of synovium and tendon
0.921 0.079 0.000
N93 Other abnormal uterine and vaginal bleeding
0.920 0.080 0.000
N30-N39 Other diseases of urinary system
0.918 0.082 0.000
E10-E14 Diabetes mellitus
0.917 0.083 0.000
G43 Migraine
0.916 0.084 0.000
F32 Depressive episode
0.913 0.087 0.000
N35 Urethral stricture
0.911 0.089 0.000
N89 Other noninflammatory disorders of vagina
0.910 0.090 0.000
I22 Subsequent myocardial infarction
0.909 0.091 0.000
N35.9 Urethral stricture, unspecified
0.907 0.093 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.902 0.098 0.000
I30-I52 Other forms of heart disease
0.898 0.102 0.000
E83 Disorders of mineral metabolism
0.897 0.103 0.000
G81 Hemiplegia
0.894 0.106 0.000
I21 Acute myocardial infarction
0.883 0.117 0.000
G43.9 Migraine, unspecified
0.872 0.128 0.000
F32.9 Depressive episode, unspecified
0.870 0.130 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.867 0.133 0.000
Chapter VII Diseases of the eye and adnexa
0.865 0.135 0.000
M65 Synovitis and tenosynovitis
0.863 0.137 0.000
S40-S49 Injuries to the shoulder and upper arm
0.862 0.138 0.000
Z50.0 Cardiac rehabilitation
0.860 0.140 0.000
G81.9 Hemiplegia, unspecified
0.859 0.141 0.000
N17 Acute renal failure
0.859 0.141 0.000
G20 Parkinson's disease
0.857 0.143 0.000
I34 Nonrheumatic mitral valve disorders
0.856 0.144 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.854 0.146 0.000
M21 Other acquired deformities of limbs
0.853 0.147 0.000
S60-S69 Injuries to the wrist and hand
0.852 0.148 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.850 0.150 0.000
N89.8 Other specified noninflammatory disorders of vagina
0.850 0.150 0.000
N90.8 Other specified noninflammatory disorders of vulva and perineum
0.847 0.153 0.000
N18 Chronic renal failure
0.844 0.156 0.000
Z50.8 Care involving use of rehabilitation procedures
0.842 0.158 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.840 0.160 0.000
M10 Gout
0.838 0.162 0.000
S70-S79 Injuries to the hip and thigh
0.835 0.165 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.834 0.166 0.000
I20 Angina pectoris
0.834 0.166 0.000
G47 Sleep disorders
0.832 0.168 0.000
N93.0 Postcoital and contact bleeding
0.831 0.169 0.000
N95 Menopausal and other perimenopausal disorders
0.829 0.171 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.829 0.171 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.828 0.172 0.000
E83.5 Disorders of calcium metabolism
0.828 0.172 0.000
M45-M49 Spondylopathies
0.828 0.172 0.000
M86-M90 Other osteopathies
0.827 0.173 0.000
I95 Hypotension
0.826 0.174 0.000
N93.8 Other specified abnormal uterine and vaginal bleeding
0.824 0.176 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.822 0.178 0.000
N94.8 Other specified conditions associated with female genital organs and menstrual cycle
0.821 0.179 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.821 0.179 0.000
G40 Epilepsy
0.818 0.182 0.000
E14 Unspecified diabetes mellitus
0.817 0.183 0.000
I34.0 Mitral (valve) insufficiency
0.816 0.184 0.000
N90.9 Noninflammatory disorder of vulva and perineum, unspecified
0.814 0.186 0.000
N20-N23 Urolithiasis
0.811 0.189 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.810 0.190 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.807 0.193 0.000
N90.5 Atrophy of vulva
0.801 0.199 0.000
N17.9 Acute renal failure, unspecified
0.801 0.199 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.800 0.200 0.000
E11 Non-insulin-dependent diabetes mellitus
0.799 0.201 0.000
Z40 Prophylactic surgery
0.799 0.201 0.000
E20-E35 Disorders of other endocrine glands
0.798 0.202 0.000
M25 Other joint disorders, not elsewhere classified
0.797 0.203 0.000
N60-N64 Disorders of breast
0.797 0.203 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.796 0.204 0.000
I95.1 Orthostatic hypotension
0.794 0.206 0.000
M34 Systemic sclerosis
0.794 0.206 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.794 0.206 0.000
I84 Haemorrhoids
0.790 0.210 0.000
F31.9 Bipolar affective disorder, unspecified
0.788 0.212 0.000
G24 Dystonia
0.787 0.212 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.786 0.214 0.000
F30 Manic episode
0.785 0.215 0.000
Z50.5 Speech therapy
0.785 0.215 0.000
F80-F89 Disorders of psychological development
0.784 0.216 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.784 0.216 0.000
I45 Other conduction disorders
0.784 0.216 0.000
S42 Fracture of shoulder and upper arm
0.781 0.219 0.000
N84 Polyp of female genital tract
0.779 0.221 0.000
M23.8 Other internal derangements of knee
0.778 0.222 0.000
S90-S99 Injuries to the ankle and foot
0.777 0.223 0.000
M06 Other rheumatoid arthritis
0.777 0.223 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.775 0.225 0.000
Z46 Fitting and adjustment of other devices
0.772 0.228 0.000
G44 Other headache syndromes
0.769 0.231 0.000
Z95.1 Presence of aortocoronary bypass graft
0.768 0.232 0.000
F03 Unspecified dementia
0.765 0.235 0.000
M10.9 Gout, unspecified
0.765 0.235 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.762 0.238 0.000
Chapter XX External causes of morbidity and mortality
0.762 0.238 0.000
N90.7 Vulvar cyst
0.762 0.238 0.000
E83.4 Disorders of magnesium metabolism
0.762 0.238 0.000
E40-E46 Malnutrition
0.761 0.239 0.000
T66-T78 Other and unspecified effects of external causes
0.759 0.241 0.000
N87 Dysplasia of cervix uteri
0.759 0.241 0.000
M07 Psoriatic and enteropathic arthropathies
0.758 0.242 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.756 0.244 0.000
Z54 Convalescence
0.754 0.246 0.000
Chapter VIII Diseases of the ear and mastoid process
0.754 0.246 0.000
S64 Injury of nerves at wrist and hand level
0.752 0.248 0.000
I84.2 Internal haemorrhoids without complication
0.751 0.249 0.000
N18.9 Chronic renal failure, unspecified
0.750 0.250 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.750 0.250 0.000
G41 Status epilepticus
0.749 0.251 0.000
Z43 Attention to artificial openings
0.749 0.251 0.000
G30-G32 Other degenerative diseases of the nervous system
0.749 0.251 0.000
F05.9 Delirium, unspecified
0.749 0.251 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.748 0.252 0.000
M91-M94 Chondropathies
0.747 0.253 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.747 0.253 0.000
M35 Other systemic involvement of connective tissue
0.746 0.254 0.000
M14 Arthropathies in other diseases classified elsewhere
0.745 0.255 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.745 0.255 0.000
Z45 Adjustment and management of implanted device
0.745 0.255 0.000
N86 Erosion and ectropion of cervix uteri
0.744 0.256 0.000
M31 Other necrotising vasculopathies
0.742 0.258 0.000
N40-N51 Diseases of male genital organs
0.742 0.258 0.000
I47 Paroxysmal tachycardia
0.741 0.259 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.741 0.259 0.000
S10-S19 Injuries to the neck
0.740 0.260 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.740 0.260 0.000
G25 Other extrapyramidal and movement disorders
0.739 0.261 0.000
M21.0 Valgus deformity, not elsewhere classified
0.739 0.261 0.000
Z92 Personal history of medical treatment
0.738 0.262 0.000
I44 Atrioventricular and left bundle-branch block
0.738 0.262 0.000
M00-M03 Infectious arthropathies
0.737 0.263 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.736 0.264 0.000
F60-F69 Disorders of adult personality and behaviour
0.735 0.265 0.000
Chapter XXII Codes for special purposes
0.735 0.265 0.000
I50 Heart failure
0.735 0.265 0.000
N90.4 Leukoplakia of vulva
0.735 0.265 0.000
S20-S29 Injuries to the thorax
0.734 0.266 0.000
N94.3 Premenstrual tension syndrome
0.733 0.266 0.000
H53-H54 Visual disturbances and blindness
0.732 0.268 0.000
M80-M85 Disorders of bone density and structure
0.732 0.268 0.000
E14.9 Without complications
0.732 0.268 0.000
I20.9 Angina pectoris, unspecified
0.728 0.272 0.000
G80 Infantile cerebral palsy
0.728 0.272 0.000
F00 Dementia in Alzheimer's disease
0.726 0.274 0.000
I21.9 Acute myocardial infarction, unspecified
0.723 0.277 0.000
N97 Female infertility
0.722 0.278 0.000
Z48 Other surgical follow-up care
0.721 0.279 0.000
Z52 Donors of organs and tissues
0.721 0.279 0.000
S50-S59 Injuries to the elbow and forearm
0.720 0.280 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.719 0.281 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.718 0.282 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
I25.5 Ischaemic cardiomyopathy
0.717 0.283 0.000
I25.4 Coronary artery aneurysm
0.717 0.283 0.000
I25.3 Aneurysm of heart
0.717 0.283 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.717 0.283 0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)
0.717 0.283 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.716 0.284 0.000
Z89 Acquired absence of limb
0.716 0.284 0.000
M60-M63 Disorders of muscles
0.715 0.284 0.000
F99-F99 Unspecified mental disorder
0.715 0.285 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.715 0.285 0.000
F70-F79 Mental retardation
0.715 0.285 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.715 0.285 0.000
N98 Complications associated with artificial fertilisation
0.713 0.286 0.000
N91 Absent, scanty and rare menstruation
0.713 0.286 0.000
N82 Fistulae involving female genital tract
0.713 0.286 0.000
N96 Habitual aborter
0.713 0.286 0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)
0.713 0.287 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.712 0.288 0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)
0.712 0.288 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.709 0.291 0.000
F29 Unspecified nonorganic psychosis
0.709 0.291 0.000
N94.6 Dysmenorrhoea, unspecified
0.709 0.291 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.709 0.291 0.000
Z49 Care involving dialysis
0.708 0.292 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.707 0.293 0.000
M45 Ankylosing spondylitis
0.707 0.293 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.707 0.293 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.706 0.293 0.000
I99 Other and unspecified disorders of circulatory system
0.706 0.294 0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases
0.706 0.294 0.000
S00-S09 Injuries to the head
0.706 0.294 0.000
Z50.6 Orthoptic training
0.706 0.294 0.000
Z50.3 Drug rehabilitation
0.706 0.294 0.000
Z50.2 Alcohol rehabilitation
0.706 0.294 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.705 0.295 0.000
G70-G73 Diseases of myoneural junction and muscle
0.705 0.295 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.704 0.296 0.000
M33 Dermatopolymyositis
0.704 0.296 0.000
M32 Systemic lupus erythematosus
0.704 0.296 0.000
M30 Polyarteritis nodosa and related conditions
0.704 0.296 0.000
I80 Phlebitis and thrombophlebitis
0.704 0.296 0.000
Z44 Fitting and adjustment of external prosthetic device
0.703 0.296 0.000
F38 Other mood [affective] disorders
0.703 0.297 0.000
F34 Persistent mood [affective] disorders
0.703 0.297 0.000
F39 Unspecified mood [affective] disorder
0.703 0.297 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.702 0.298 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.701 0.299 0.000
M23.4 Loose body in knee
0.698 0.301 0.000
G90-G99 Other disorders of the nervous system
0.698 0.302 0.000
H55-H59 Other disorders of eye and adnexa
0.698 0.302 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.698 0.302 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.697 0.303 0.000
Q60-Q64 Congenital malformations of the urinary system
0.695 0.305 0.000
G47.1 Disorders of excessive somnolence [hypersomnias]
0.695 0.305 0.000
N60 Benign mammary dysplasia
0.693 0.307 0.000
M23.9 Internal derangement of knee, unspecified
0.692 0.308 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.692 0.308 0.000
M23.5 Chronic instability of knee
0.692 0.308 0.000
M23.1 Discoid meniscus (congenital)
0.692 0.308 0.000
M23.0 Cystic meniscus
0.692 0.308 0.000
T79-T79 Certain early complications of trauma
0.691 0.309 0.000
T33-T35 Frostbite
0.691 0.309 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.691 0.309 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.691 0.309 0.000
T00-T07 Injuries involving multiple body regions
0.691 0.309 0.000
E88 Other metabolic disorders
0.691 0.309 0.000
E85 Amyloidosis
0.691 0.309 0.000
E84 Cystic fibrosis
0.691 0.309 0.000
E79 Disorders of purine and pyrimidine metabolism
0.691 0.309 0.000
E77 Disorders of glycoprotein metabolism
0.691 0.309 0.000
E76 Disorders of glycosaminoglycan metabolism
0.691 0.309 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.691 0.309 0.000
E74 Other disorders of carbohydrate metabolism
0.691 0.309 0.000
E73 Lactose intolerance
0.691 0.309 0.000
E72 Other disorders of amino-acid metabolism
0.691 0.309 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.691 0.309 0.000
E70 Disorders of aromatic amino-acid metabolism
0.691 0.309 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.691 0.309 0.000
S72 Fracture of femur
0.691 0.309 0.000
N90.6 Hypertrophy of vulva
0.690 0.310 0.000
N90.3 Dysplasia of vulva, unspecified
0.690 0.310 0.000
N90.2 Severe vulvar dysplasia, not elsewhere classified
0.690 0.310 0.000
N90.1 Moderate vulvar dysplasia
0.690 0.310 0.000
N90.0 Mild vulvar dysplasia
0.690 0.310 0.000
N21 Calculus of lower urinary tract
0.690 0.310 0.000
N84.1 Polyp of cervix uteri
0.688 0.312 0.000
I60-I69 Cerebrovascular diseases
0.687 0.313 0.000
N99-N99 Other disorders of the genitourinary system
0.686 0.313 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.686 0.314 0.000
N95.9 Menopausal and perimenopausal disorder, unspecified
0.685 0.315 0.000
E83.3 Disorders of phosphorus metabolism
0.685 0.315 0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)
0.685 0.315 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.684 0.316 0.000
S70 Superficial injury of hip and thigh
0.683 0.317 0.000
M10.99 Gout, unspecified (Site unspecified)
0.683 0.317 0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular
0.683 0.317 0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified
0.682 0.318 0.000
M47 Spondylosis
0.681 0.319 0.000
Z29 Need for other prophylactic measures
0.680 0.320 0.000
I24 Other acute ischaemic heart diseases
0.679 0.321 0.000
G82 Paraplegia and tetraplegia
0.679 0.321 0.000
N95.1 Menopausal and female climacteric states
0.679 0.321 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.678 0.322 0.000
G23 Other degenerative diseases of basal ganglia
0.677 0.323 0.000
G21 Secondary Parkinsonism
0.677 0.323 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.677 0.323 0.000
G22 Parkinsonism in diseases classified elsewhere
0.677 0.323 0.000
G60 Hereditary and idiopathic neuropathy
0.677 0.323 0.000
M67 Other disorders of synovium and tendon
0.677 0.323 0.000
G24.9 Dystonia, unspecified
0.675 0.325 0.000
M24 Other specific joint derangements
0.674 0.326 0.000
M12 Other specific arthropathies
0.674 0.326 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.674 0.326 0.000
M08 Juvenile arthritis
0.674 0.326 0.000
I20.1 Angina pectoris with documented spasm
0.674 0.326 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.672 0.328 0.000
E78.8 Other disorders of lipoprotein metabolism
0.672 0.328 0.000
E78.6 Lipoprotein deficiency
0.672 0.328 0.000
E78.4 Other hyperlipidaemia
0.672 0.328 0.000
E78.3 Hyperchylomicronaemia
0.672 0.328 0.000
E78.2 Mixed hyperlipidaemia
0.672 0.328 0.000
E78.1 Pure hyperglyceridaemia
0.672 0.328 0.000
Z84 Family history of other conditions
0.671 0.329 0.000
M05 Seropositive rheumatoid arthritis
0.671 0.329 0.000
N30 Cystitis
0.671 0.329 0.000
M25.5 Pain in joint
0.670 0.330 0.000
I34.1 Mitral (valve) prolapse
0.670 0.330 0.000
E13 Other specified diabetes mellitus
0.670 0.330 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.669 0.331 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.669 0.331 0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms
0.668 0.332 0.000
G83 Other paralytic syndromes
0.668 0.332 0.000
I38 Endocarditis, valve unspecified
0.668 0.332 0.000
M65.3 Trigger finger
0.667 0.333 0.000
S80-S89 Injuries to the knee and lower leg
0.665 0.334 0.000
Z83 Family history of other specific disorders
0.665 0.335 0.000
Z43.6 Attention to other artificial openings of urinary tract
0.665 0.335 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.665 0.335 0.000
M89 Other disorders of bone
0.665 0.335 0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.664 0.336 0.000
M70-M79 Other soft tissue disorders
0.664 0.336 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.663 0.337 0.000
F02 Dementia in other diseases classified elsewhere
0.663 0.337 0.000
F09 Unspecified organic or symptomatic mental disorder
0.663 0.337 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.663 0.337 0.000
Z93 Artificial opening status
0.662 0.338 0.000
I45.9 Conduction disorder, unspecified
0.662 0.338 0.000
F31.8 Other bipolar affective disorders
0.661 0.339 0.000
F31.7 Bipolar affective disorder, currently in remission
0.661 0.339 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.661 0.339 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.661 0.339 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.661 0.339 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.661 0.339 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.660 0.339 0.000
M66 Spontaneous rupture of synovium and tendon
0.660 0.339 0.000
F01 Vascular dementia
0.660 0.340 0.000
S60 Superficial injury of wrist and hand
0.660 0.340 0.000
M34.9 Systemic sclerosis, unspecified
0.659 0.341 0.000
N37 Urethral disorders in diseases classified elsewhere
0.658 0.342 0.000
N34 Urethritis and urethral syndrome
0.658 0.342 0.000
N33 Bladder disorders in diseases classified elsewhere
0.658 0.342 0.000
Z85 Personal history of malignant neoplasm
0.658 0.342 0.000
Z42 Follow-up care involving plastic surgery
0.658 0.342 0.000
E12 Malnutrition-related diabetes mellitus
0.658 0.342 0.000
N88 Other noninflammatory disorders of cervix uteri
0.658 0.342 0.000
F33 Recurrent depressive disorder
0.658 0.342 0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)
0.658 0.342 0.000
N18.4 Chronic kidney disease, stage 4
0.657 0.343 0.000
F23 Acute and transient psychotic disorders
0.657 0.343 0.000
G43.8 Other migraine
0.657 0.343 0.000
G43.3 Complicated migraine
0.657 0.343 0.000
G43.2 Status migrainosus
0.657 0.343 0.000
G43.1 Migraine with aura [classical migraine]
0.657 0.343 0.000
G43.0 Migraine without aura [common migraine]
0.657 0.343 0.000
S64.2 Injury of radial nerve at wrist and hand level
0.657 0.343 0.000
E65-E68 Obesity and other hyperalimentation
0.655 0.345 0.000
F32.8 Other depressive episodes
0.655 0.345 0.000
F32.0 Mild depressive episode
0.655 0.345 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.655 0.345 0.000
H90-H95 Other disorders of ear
0.654 0.346 0.000
I30 Acute pericarditis
0.654 0.346 0.000
I45.6 Preexcitation syndrome
0.654 0.346 0.000
S42.2 Fracture of upper end of humerus
0.654 0.346 0.000
M21.3 Wrist or foot drop (acquired)
0.654 0.346 0.000
N35.8 Other urethral stricture
0.653 0.347 0.000
N35.1 Postinfective urethral stricture, not elsewhere classified
0.653 0.347 0.000
N35.0 Posttraumatic urethral stricture
0.653 0.347 0.000
S69 Other and unspecified injuries of wrist and hand
0.653 0.347 0.000
N89.9 Noninflammatory disorder of vagina, unspecified
0.653 0.347 0.000
N89.7 Haematocolpos
0.653 0.347 0.000
N89.6 Tight hymenal ring
0.653 0.347 0.000
N89.5 Stricture and atresia of vagina
0.653 0.347 0.000
N89.4 Leukoplakia of vagina
0.653 0.347 0.000
N89.3 Dysplasia of vagina, unspecified
0.653 0.347 0.000
N89.2 Severe vaginal dysplasia, not elsewhere classified
0.653 0.347 0.000
N89.1 Moderate vaginal dysplasia
0.653 0.347 0.000
N89.0 Mild vaginal dysplasia
0.653 0.347 0.000
Q80-Q89 Other congenital malformations
0.652 0.348 0.000
S42.0 Fracture of clavicle
0.652 0.348 0.000
I22.8 Subsequent myocardial infarction of other sites
0.652 0.348 0.000
N18.3 Chronic kidney disease, stage 3
0.652 0.348 0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)
0.651 0.348 0.000
I44.7 Left bundle-branch block, unspecified
0.651 0.349 0.000
M25.8 Other specified joint disorders
0.651 0.349 0.000
M86 Osteomyelitis
0.651 0.349 0.000
I84.1 Internal haemorrhoids with other complications
0.651 0.349 0.000
E11.5 With peripheral circulatory complications
0.649 0.351 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.648 0.352 0.000
N94.9 Unspecified condition associated with female genital organs and menstrual cycle
0.647 0.353 0.000
N94.5 Secondary dysmenorrhoea
0.647 0.353 0.000
N94.4 Primary dysmenorrhoea
0.647 0.353 0.000
N94.2 Vaginismus
0.647 0.353 0.000
N94.0 Mittelschmerz
0.647 0.353 0.000
N87.9 Dysplasia of cervix uteri, unspecified
0.647 0.353 0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.646 0.354 0.000
E11.4 With neurological complications
0.646 0.354 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.646 0.354 0.000
F30.9 Manic episode, unspecified
0.645 0.355 0.000
M11 Other crystal arthropathies
0.645 0.355 0.000
N92 Excessive, frequent and irregular menstruation
0.645 0.355 0.000
N00-N08 Glomerular diseases
0.645 0.355 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.644 0.356 0.000
I52 Other heart disorders in diseases classified elsewhere
0.644 0.356 0.000
I48 Atrial fibrillation and flutter
0.644 0.356 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.644 0.356 0.000
I41 Myocarditis in diseases classified elsewhere
0.644 0.356 0.000
I40 Acute myocarditis
0.644 0.356 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.644 0.356 0.000
I37 Pulmonary valve disorders
0.644 0.356 0.000
I36 Nonrheumatic tricuspid valve disorders
0.644 0.356 0.000
I32 Pericarditis in diseases classified elsewhere
0.644 0.356 0.000
M40-M43 Deforming dorsopathies
0.644 0.356 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.643 0.357 0.000
E83.8 Other disorders of mineral metabolism
0.643 0.357 0.000
E83.2 Disorders of zinc metabolism
0.643 0.357 0.000
E83.0 Disorders of copper metabolism
0.643 0.357 0.000
N95.3 States associated with artificial menopause
0.642 0.358 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.642 0.358 0.000
I85 Oesophageal varices
0.642 0.358 0.000
G81.1 Spastic hemiplegia
0.641 0.359 0.000
G81.0 Flaccid hemiplegia
0.641 0.359 0.000
M50-M54 Other dorsopathies
0.640 0.360 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.640 0.360 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.639 0.361 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.638 0.362 0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)
0.637 0.362 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.637 0.363 0.000
E16 Other disorders of pancreatic internal secretion
0.636 0.364 0.000
H02 Other disorders of eyelid
0.635 0.365 0.000
G56 Mononeuropathies of upper limb
0.635 0.365 0.000
M06.9 Rheumatoid arthritis, unspecified
0.635 0.365 0.000
H10-H13 Disorders of conjunctiva
0.635 0.365 0.000
I10-I15 Hypertensive diseases
0.635 0.365 0.000
E11.2 With renal complications
0.635 0.365 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.635 0.365 0.000
F42 Obsessive-compulsive disorder
0.634 0.365 0.000
N95.8 Other specified menopausal and perimenopausal disorders
0.634 0.366 0.000
E11.6 With other specified complications
0.634 0.366 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.633 0.367 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.633 0.367 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.633 0.367 0.000
I50.0 Congestive heart failure
0.633 0.367 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.632 0.368 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.631 0.368 0.000
F81 Specific developmental disorders of scholastic skills
0.631 0.369 0.000
I81 Portal vein thrombosis
0.631 0.369 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.631 0.369 0.000
N18.5 Chronic kidney disease, stage 5
0.631 0.369 0.000
M07.3 Other psoriatic arthropathies
0.628 0.372 0.000
Z45.0 Adjustment and management of cardiac pacemaker
0.628 0.372 0.000
I84.5 External haemorrhoids without complication
0.627 0.372 0.000
I87 Other disorders of veins
0.627 0.373 0.000
H02.8 Other specified disorders of eyelid
0.627 0.373 0.000
E11.3 With ophthalmic complications
0.627 0.373 0.000
I47.1 Supraventricular tachycardia
0.627 0.373 0.000
Q00-Q07 Congenital malformations of the nervous system
0.626 0.374 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.626 0.374 0.000
N64 Other disorders of breast
0.626 0.374 0.000
F20 Schizophrenia
0.626 0.374 0.000
I82 Other venous embolism and thrombosis
0.625 0.374 0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)
0.625 0.375 0.000
N95.0 Postmenopausal bleeding
0.625 0.375 0.000
N36 Other disorders of urethra
0.624 0.375 0.000
Z89.4 Acquired absence of foot and ankle
0.624 0.376 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.624 0.376 0.000
N45 Orchitis and epididymitis
0.623 0.377 0.000
M10.96 Gout, unspecified (Lower leg)
0.622 0.378 0.000
I88 Nonspecific lymphadenitis
0.622 0.378 0.000
E14.3 With ophthalmic complications
0.621 0.379 0.000
I50.1 Left ventricular failure
0.621 0.379 0.000
M13 Other arthritis
0.621 0.379 0.000
I05-I09 Chronic rheumatic heart diseases
0.620 0.379 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.620 0.380 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.620 0.380 0.000
G44.2 Tension-type headache
0.620 0.380 0.000
H53 Visual disturbances
0.620 0.380 0.000
S68 Traumatic amputation of wrist and hand
0.619 0.381 0.000
I84.9 Unspecified haemorrhoids without complication
0.619 0.381 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.619 0.381 0.000
M65.8 Other synovitis and tenosynovitis
0.618 0.381 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.618 0.381 0.000
M65.2 Calcific tendinitis
0.618 0.381 0.000
M65.1 Other infective (teno)synovitis
0.618 0.381 0.000
M65.0 Abscess of tendon sheath
0.618 0.381 0.000
Z47 Other orthopaedic follow-up care
0.618 0.382 0.000
M47.8 Other spondylosis
0.618 0.382 0.000
I33 Acute and subacute endocarditis
0.618 0.382 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.618 0.382 0.000
S48 Traumatic amputation of shoulder and upper arm
0.618 0.382 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.618 0.382 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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