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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs34785368
log Bayes Factor = 15.6724
Chromosome 13   position 62,810,930  (GRCh37) Explore rs34785368 on Ensembl!
Variant rs34785368 is part of Cluster X0268

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter II Neoplasms
0.999 0.001 0.000
Chapter X Diseases of the respiratory system
0.999 0.001 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.998 0.002 0.000
Chapter V Mental and behavioural disorders
0.997 0.003 0.000
Chapter XXI Factors influencing health status and contact with health services
0.996 0.004 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.992 0.008 0.000
R50-R69 General symptoms and signs
0.991 0.009 0.000
Chapter XIV Diseases of the genitourinary system
0.989 0.011 0.000
Chapter VIII Diseases of the ear and mastoid process
0.982 0.018 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.981 0.019 0.000
R55 Syncope and collapse
0.979 0.021 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.979 0.021 0.000
N10-N16 Renal tubulo-interstitial diseases
0.977 0.023 0.000
E10-E14 Diabetes mellitus
0.973 0.027 0.000
J40-J47 Chronic lower respiratory diseases
0.968 0.032 0.000
N13 Obstructive and reflux uropathy
0.966 0.034 0.000
N17-N19 Renal failure
0.965 0.035 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.962 0.038 0.000
E11 Non-insulin-dependent diabetes mellitus
0.956 0.044 0.000
F30-F39 Mood [affective] disorders
0.954 0.046 0.000
R53 Malaise and fatigue
0.950 0.050 0.000
H65-H75 Diseases of middle ear and mastoid
0.950 0.050 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.948 0.052 0.000
Chapter I Certain infectious and parasitic diseases
0.946 0.054 0.000
J44 Other chronic obstructive pulmonary disease
0.944 0.056 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.939 0.061 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.938 0.062 0.000
N17 Acute renal failure
0.938 0.062 0.000
Chapter IX Diseases of the circulatory system
0.936 0.064 0.000
Chapter VII Diseases of the eye and adnexa
0.934 0.066 0.000
E11.9 Without complications
0.934 0.066 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.929 0.071 0.000
I30-I52 Other forms of heart disease
0.927 0.073 0.000
F32 Depressive episode
0.926 0.074 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.925 0.075 0.000
J20-J22 Other acute lower respiratory infections
0.925 0.075 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.924 0.076 0.000
Chapter XI Diseases of the digestive system
0.923 0.077 0.000
Chapter VI Diseases of the nervous system
0.920 0.080 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.917 0.083 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.916 0.084 0.000
F32.9 Depressive episode, unspecified
0.913 0.087 0.000
E20-E35 Disorders of other endocrine glands
0.912 0.088 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.909 0.091 0.000
N17.9 Acute renal failure, unspecified
0.905 0.095 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.903 0.097 0.000
R61 Hyperhidrosis
0.899 0.101 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.897 0.103 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.897 0.103 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.895 0.105 0.000
C64-C68 Malignant neoplasms of urinary tract
0.895 0.105 0.000
E70-E90 Metabolic disorders
0.893 0.107 0.000
Z80 Family history of malignant neoplasm
0.891 0.109 0.000
J90-J94 Other diseases of pleura
0.891 0.109 0.000
S80-S89 Injuries to the knee and lower leg
0.889 0.111 0.000
F41 Other anxiety disorders
0.889 0.111 0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances
0.888 0.112 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.886 0.114 0.000
J45 Asthma
0.886 0.114 0.000
K04 Diseases of pulp and periapical tissues
0.886 0.114 0.000
I50 Heart failure
0.884 0.116 0.000
R54 Senility
0.881 0.119 0.000
N18 Chronic renal failure
0.880 0.120 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.877 0.123 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.876 0.124 0.000
N13.3 Other and unspecified hydronephrosis
0.873 0.126 0.000
D00-D09 In situ neoplasms
0.873 0.127 0.000
J30-J39 Other diseases of upper respiratory tract
0.868 0.132 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.866 0.134 0.000
I47 Paroxysmal tachycardia
0.861 0.139 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.861 0.139 0.000
S60-S69 Injuries to the wrist and hand
0.859 0.141 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.854 0.146 0.000
C78.0 Secondary malignant neoplasm of lung
0.852 0.148 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.851 0.149 0.000
B35-B49 Mycoses
0.849 0.151 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.848 0.152 0.000
R59 Enlarged lymph nodes
0.847 0.153 0.000
H66 Suppurative and unspecified otitis media
0.847 0.153 0.000
K04.7 Periapical abscess without sinus
0.847 0.153 0.000
Z73 Problems related to life-management difficulty
0.846 0.154 0.000
F41.2 Mixed anxiety and depressive disorder
0.846 0.154 0.000
C78.7 Secondary malignant neoplasm of liver
0.846 0.154 0.000
C78.2 Secondary malignant neoplasm of pleura
0.844 0.156 0.000
J22 Unspecified acute lower respiratory infection
0.844 0.156 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.842 0.158 0.000
G90-G99 Other disorders of the nervous system
0.842 0.158 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.841 0.159 0.000
I47.2 Ventricular tachycardia
0.837 0.163 0.000
Z80.3 Family history of malignant neoplasm of breast
0.835 0.165 0.000
Z80.4 Family history of malignant neoplasm of genital organs
0.835 0.165 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.835 0.165 0.000
S70-S79 Injuries to the hip and thigh
0.834 0.166 0.000
R61.9 Hyperhidrosis, unspecified
0.834 0.166 0.000
F10.1 Harmful use
0.832 0.168 0.000
I60-I69 Cerebrovascular diseases
0.830 0.170 0.000
N00-N08 Glomerular diseases
0.830 0.170 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.829 0.170 0.000
Z02 Examination and encounter for administrative purposes
0.829 0.171 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.828 0.172 0.000
H00 Hordeolum and chalazion
0.826 0.174 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.824 0.176 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.824 0.176 0.000
K90-K93 Other diseases of the digestive system
0.822 0.178 0.000
B95-B98 Bacterial, viral and other infectious agents
0.819 0.181 0.000
H80-H83 Diseases of inner ear
0.819 0.181 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.817 0.183 0.000
Z88.3 Personal history of allergy to other anti-infective agents
0.817 0.183 0.000
S00-S09 Injuries to the head
0.816 0.184 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.815 0.185 0.000
J45.9 Asthma, unspecified
0.814 0.186 0.000
Z57 Occupational exposure to risk-factors
0.812 0.188 0.000
E65-E68 Obesity and other hyperalimentation
0.810 0.190 0.000
C80 Malignant neoplasm without specification of site
0.810 0.190 0.000
J92 Pleural plaque
0.810 0.190 0.000
I50.9 Heart failure, unspecified
0.809 0.191 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.808 0.192 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.808 0.192 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.808 0.192 0.000
F10.3 Withdrawal state
0.805 0.195 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.804 0.196 0.000
I30 Acute pericarditis
0.803 0.197 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.801 0.198 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.801 0.199 0.000
C79 Secondary malignant neoplasm of other sites
0.800 0.200 0.000
S82 Fracture of lower leg, including ankle
0.800 0.200 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.799 0.201 0.000
D10-D36 Benign neoplasms
0.798 0.202 0.000
R68 Other general symptoms and signs
0.798 0.202 0.000
J95-J99 Other diseases of the respiratory system
0.795 0.205 0.000
K11 Diseases of salivary glands
0.794 0.206 0.000
K35-K38 Diseases of appendix
0.793 0.207 0.000
R47-R49 Symptoms and signs involving speech and voice
0.793 0.207 0.000
Chapter XX External causes of morbidity and mortality
0.793 0.207 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.792 0.208 0.000
R27 Other lack of coordination
0.789 0.211 0.000
H74 Other disorders of middle ear and mastoid
0.789 0.211 0.000
C34 Malignant neoplasm of bronchus and lung
0.789 0.211 0.000
Z02.8 Other examinations for administrative purposes
0.788 0.212 0.000
Z88.4 Personal history of allergy to anaesthetic agent
0.784 0.216 0.000
H60-H62 Diseases of external ear
0.784 0.216 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.783 0.217 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.782 0.218 0.000
J32 Chronic sinusitis
0.781 0.219 0.000
Z73.9 Problem related to life-management difficulty, unspecified
0.780 0.220 0.000
R29.6 Tendency to fall, not elsewhere classified
0.780 0.220 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.780 0.220 0.000
N17.0 Acute renal failure with tubular necrosis
0.778 0.222 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.775 0.225 0.000
F99-F99 Unspecified mental disorder
0.774 0.226 0.000
H00.1 Chalazion
0.774 0.226 0.000
G62 Other polyneuropathies
0.774 0.226 0.000
R63 Symptoms and signs concerning food and fluid intake
0.774 0.226 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.773 0.227 0.000
E86 Volume depletion
0.773 0.227 0.000
S61 Open wound of wrist and hand
0.773 0.227 0.000
J81 Pulmonary oedema
0.772 0.228 0.000
Z89 Acquired absence of limb
0.772 0.228 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.772 0.228 0.000
E11.0 With coma
0.772 0.228 0.000
D04 Carcinoma in situ of skin
0.770 0.230 0.000
K04.8 Radicular cyst
0.770 0.230 0.000
E87.6 Hypokalaemia
0.768 0.232 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.765 0.234 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.765 0.235 0.000
N13.6 Pyonephrosis
0.764 0.236 0.000
F60-F69 Disorders of adult personality and behaviour
0.764 0.236 0.000
Z03.8 Observation for other suspected diseases and conditions
0.762 0.238 0.000
B37 Candidiasis
0.761 0.239 0.000
K92 Other diseases of digestive system
0.758 0.242 0.000
Z84 Family history of other conditions
0.757 0.243 0.000
E27 Other disorders of adrenal gland
0.756 0.244 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.756 0.244 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.756 0.244 0.000
R41.0 Disorientation, unspecified
0.755 0.245 0.000
I35 Nonrheumatic aortic valve disorders
0.755 0.245 0.000
J20 Acute bronchitis
0.755 0.245 0.000
E11.2 With renal complications
0.753 0.247 0.000
H73 Other disorders of tympanic membrane
0.753 0.247 0.000
H65 Nonsuppurative otitis media
0.752 0.248 0.000
H02 Other disorders of eyelid
0.752 0.248 0.000
A30-A49 Other bacterial diseases
0.752 0.248 0.000
Z57.2 Occupational exposure to dust
0.751 0.249 0.000
Z98 Other postsurgical states
0.750 0.250 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.750 0.250 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.747 0.253 0.000
N92 Excessive, frequent and irregular menstruation
0.747 0.253 0.000
H10-H13 Disorders of conjunctiva
0.747 0.253 0.000
I44 Atrioventricular and left bundle-branch block
0.746 0.254 0.000
Z99.1 Dependence on respirator
0.745 0.255 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.744 0.256 0.000
N92.0 Excessive and frequent menstruation with regular cycle
0.744 0.256 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.743 0.257 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.743 0.257 0.000
H66.3 Other chronic suppurative otitis media
0.743 0.257 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.742 0.258 0.000
I50.1 Left ventricular failure
0.742 0.258 0.000
N18.4 Chronic kidney disease, stage 4
0.741 0.259 0.000
N18.8 Other chronic renal failure
0.739 0.261 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.739 0.261 0.000
E11.5 With peripheral circulatory complications
0.738 0.262 0.000
J46 Status asthmaticus
0.738 0.262 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.738 0.262 0.000
Z71.8 Other specified counselling
0.737 0.263 0.000
C67 Malignant neoplasm of bladder
0.736 0.264 0.000
T79-T79 Certain early complications of trauma
0.735 0.265 0.000
N18.9 Chronic renal failure, unspecified
0.734 0.266 0.000
J60-J70 Lung diseases due to external agents
0.734 0.266 0.000
H72 Perforation of tympanic membrane
0.733 0.267 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.733 0.267 0.000
N10 Acute tubulo-interstitial nephritis
0.733 0.267 0.000
Z90.7 Acquired absence of genital organ(s)
0.732 0.268 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.732 0.268 0.000
F43 Reaction to severe stress, and adjustment disorders
0.732 0.268 0.000
E13 Other specified diabetes mellitus
0.729 0.271 0.000
I33 Acute and subacute endocarditis
0.728 0.272 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.727 0.273 0.000
Z99.2 Dependence on renal dialysis
0.727 0.273 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.726 0.273 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.725 0.275 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.725 0.275 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.724 0.276 0.000
E40-E46 Malnutrition
0.724 0.276 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.723 0.277 0.000
Chapter XXII Codes for special purposes
0.721 0.279 0.000
R52 Pain, not elsewhere classified
0.720 0.280 0.000
Z13 Special screening examination for other diseases and disorders
0.720 0.280 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.719 0.280 0.000
J92.0 Pleural plaque with presence of asbestos
0.717 0.283 0.000
N99-N99 Other disorders of the genitourinary system
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
S70 Superficial injury of hip and thigh
0.717 0.283 0.000
N18.5 Chronic kidney disease, stage 5
0.716 0.283 0.000
D12.5 Sigmoid colon
0.716 0.284 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.716 0.284 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.716 0.284 0.000
A80-A89 Viral infections of the central nervous system
0.715 0.285 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.715 0.285 0.000
F80-F89 Disorders of psychological development
0.715 0.285 0.000
F70-F79 Mental retardation
0.715 0.285 0.000
H90-H95 Other disorders of ear
0.715 0.285 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.715 0.285 0.000
K92.1 Melaena
0.714 0.286 0.000
N89 Other noninflammatory disorders of vagina
0.714 0.286 0.000
R59.9 Enlarged lymph nodes, unspecified
0.714 0.286 0.000
G70-G73 Diseases of myoneural junction and muscle
0.713 0.286 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.713 0.287 0.000
H69 Other disorders of Eustachian tube
0.713 0.287 0.000
I30.9 Acute pericarditis, unspecified
0.713 0.287 0.000
J32.9 Chronic sinusitis, unspecified
0.711 0.289 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.711 0.289 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.710 0.289 0.000
R62 Lack of expected normal physiological development
0.710 0.289 0.000
R57 Shock, not elsewhere classified
0.710 0.289 0.000
R64 Cachexia
0.710 0.289 0.000
R58 Haemorrhage, not elsewhere classified
0.710 0.289 0.000
Z88.7 Personal history of allergy to serum and vaccine
0.710 0.290 0.000
F45 Somatoform disorders
0.710 0.290 0.000
Z71.3 Dietary counselling and surveillance
0.709 0.291 0.000
H04 Disorders of lachrymal system
0.709 0.291 0.000
E11.4 With neurological complications
0.709 0.291 0.000
E16 Other disorders of pancreatic internal secretion
0.709 0.291 0.000
K01 Embedded and impacted teeth
0.709 0.291 0.000
F33 Recurrent depressive disorder
0.709 0.291 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.708 0.292 0.000
I46 Cardiac arrest
0.707 0.293 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.706 0.294 0.000
Z99.8 Dependence on other enabling machines and devices
0.706 0.294 0.000
F32.0 Mild depressive episode
0.705 0.295 0.000
H05 Disorders of orbit
0.705 0.295 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.704 0.296 0.000
T33-T35 Frostbite
0.704 0.296 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.704 0.296 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.704 0.296 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.704 0.296 0.000
T00-T07 Injuries involving multiple body regions
0.704 0.296 0.000
S10-S19 Injuries to the neck
0.704 0.296 0.000
I38 Endocarditis, valve unspecified
0.703 0.297 0.000
Z90.5 Acquired absence of kidney
0.703 0.297 0.000
E14 Unspecified diabetes mellitus
0.703 0.297 0.000
I50.0 Congestive heart failure
0.702 0.298 0.000
C92 Myeloid leukaemia
0.702 0.298 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.702 0.298 0.000
Z83 Family history of other specific disorders
0.702 0.298 0.000
N03 Chronic nephritic syndrome
0.701 0.299 0.000
Z90.3 Acquired absence of part of stomach
0.701 0.299 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.701 0.299 0.000
N15 Other renal tubulo-interstitial diseases
0.701 0.299 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.701 0.299 0.000
N11 Chronic tubulo-interstitial nephritis
0.701 0.299 0.000
S90-S99 Injuries to the ankle and foot
0.701 0.299 0.000
G95 Other diseases of spinal cord
0.700 0.300 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.700 0.300 0.000
J00-J06 Acute upper respiratory infections
0.698 0.302 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.698 0.302 0.000
E12 Malnutrition-related diabetes mellitus
0.698 0.302 0.000
K10 Other diseases of jaws
0.697 0.303 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.697 0.303 0.000
R26 Abnormalities of gait and mobility
0.697 0.303 0.000
G62.9 Polyneuropathy, unspecified
0.696 0.304 0.000
S50-S59 Injuries to the elbow and forearm
0.695 0.305 0.000
J41 Simple and mucopurulent chronic bronchitis
0.694 0.306 0.000
J42 Unspecified chronic bronchitis
0.694 0.306 0.000
C45 Mesothelioma
0.694 0.306 0.000
D05 Carcinoma in situ of breast
0.693 0.307 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.693 0.307 0.000
N13.7 Vesicoureteral-reflux-associated uropathy
0.693 0.307 0.000
K35 Acute appendicitis
0.693 0.307 0.000
H71 Cholesteatoma of middle ear
0.692 0.308 0.000
C15-C26 Malignant neoplasms of digestive organs
0.692 0.308 0.000
R27.0 Ataxia, unspecified
0.692 0.308 0.000
Z63 Other problems related to primary support group, including family circumstances
0.691 0.309 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.690 0.310 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.690 0.310 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.690 0.310 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.690 0.310 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.690 0.310 0.000
R20 Disturbances of skin sensation
0.690 0.310 0.000
K09 Cysts of oral region, not elsewhere classified
0.690 0.310 0.000
E21.0 Primary hyperparathyroidism
0.690 0.310 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.689 0.311 0.000
H55-H59 Other disorders of eye and adnexa
0.689 0.311 0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters
0.689 0.311 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.689 0.311 0.000
F10.2 Dependence syndrome
0.689 0.311 0.000
Z91.1 Personal history of noncompliance with medical treatment and regimen
0.688 0.312 0.000
B15-B19 Viral hepatitis
0.688 0.312 0.000
J33 Nasal polyp
0.687 0.313 0.000
R47 Speech disturbances, not elsewhere classified
0.687 0.313 0.000
E11.8 With unspecified complications
0.685 0.315 0.000
E11.7 With multiple complications
0.685 0.315 0.000
E11.6 With other specified complications
0.685 0.315 0.000
E11.1 With ketoacidosis
0.685 0.315 0.000
E28 Ovarian dysfunction
0.685 0.315 0.000
N60-N64 Disorders of breast
0.685 0.315 0.000
S82.8 Fractures of other parts of lower leg
0.685 0.315 0.000
F38 Other mood [affective] disorders
0.684 0.316 0.000
F34 Persistent mood [affective] disorders
0.684 0.316 0.000
F30 Manic episode
0.684 0.316 0.000
F39 Unspecified mood [affective] disorder
0.684 0.316 0.000
C34.9 Bronchus or lung, unspecified
0.684 0.316 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.684 0.316 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.683 0.317 0.000
N13.4 Hydroureter
0.681 0.319 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.681 0.319 0.000
H70 Mastoiditis and related conditions
0.681 0.319 0.000
H68 Eustachian salpingitis and obstruction
0.681 0.319 0.000
H67 Otitis media in diseases classified elsewhere
0.681 0.319 0.000
J45.0 Predominantly allergic asthma
0.681 0.319 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.680 0.320 0.000
K11.2 Sialoadenitis
0.680 0.320 0.000
Z81 Family history of mental and behavioural disorders
0.679 0.320 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.679 0.321 0.000
S32 Fracture of lumbar spine and pelvis
0.679 0.321 0.000
E50-E64 Other nutritional deficiencies
0.679 0.321 0.000
B99-B99 Other infectious diseases
0.678 0.322 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.678 0.322 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.678 0.322 0.000
B65-B83 Helminthiases
0.678 0.322 0.000
B50-B64 Protozoal diseases
0.678 0.322 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.678 0.322 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.678 0.322 0.000
A75-A79 Rickettsioses
0.678 0.322 0.000
A70-A74 Other diseases caused by chlamydiae
0.678 0.322 0.000
A65-A69 Other spirochaetal diseases
0.678 0.322 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.678 0.322 0.000
A20-A28 Certain zoonotic bacterial diseases
0.678 0.322 0.000
A15-A19 Tuberculosis
0.678 0.322 0.000
R76 Other abnormal immunological findings in serum
0.677 0.323 0.000
J90 Pleural effusion, not elsewhere classified
0.677 0.323 0.000
H66.9 Otitis media, unspecified
0.676 0.324 0.000
E66 Obesity
0.676 0.324 0.000
Z88.2 Personal history of allergy to sulphonamides
0.676 0.324 0.000
N80 Endometriosis
0.676 0.324 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.675 0.325 0.000
K65-K67 Diseases of peritoneum
0.674 0.325 0.000
N13.8 Other obstructive and reflux uropathy
0.673 0.326 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.673 0.327 0.000
H74.4 Polyp of middle ear
0.673 0.327 0.000
Z76 Persons encountering health services in other circumstances
0.673 0.327 0.000
Z70 Counselling related to sexual attitude, behaviour and orientation
0.673 0.327 0.000
F48 Other neurotic disorders
0.673 0.327 0.000
F44 Dissociative [conversion] disorders
0.673 0.327 0.000
F42 Obsessive-compulsive disorder
0.673 0.327 0.000
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung
0.672 0.327 0.000
N17.8 Other acute renal failure
0.672 0.328 0.000
N17.2 Acute renal failure with medullary necrosis
0.672 0.328 0.000
N17.1 Acute renal failure with acute cortical necrosis
0.672 0.328 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.672 0.328 0.000
K05 Gingivitis and periodontal diseases
0.672 0.328 0.000
C51-C58 Malignant neoplasms of female genital organs
0.672 0.328 0.000
J34 Other disorders of nose and nasal sinuses
0.672 0.328 0.000
I00-I02 Acute rheumatic fever
0.671 0.329 0.000
Q50-Q56 Congenital malformations of genital organs
0.671 0.329 0.000
Z90.2 Acquired absence of lung [part of]
0.671 0.329 0.000
Z88.5 Personal history of allergy to narcotic agent
0.671 0.329 0.000
Z88.1 Personal history of allergy to other antibiotic agents
0.670 0.330 0.000
T66-T78 Other and unspecified effects of external causes
0.669 0.330 0.000
C80.0 Malignant neoplasm, primary site unknown, so stated
0.668 0.332 0.000
R59.1 Generalised enlarged lymph nodes
0.668 0.332 0.000
N89.8 Other specified noninflammatory disorders of vagina
0.667 0.333 0.000
J92.9 Pleural plaque without asbestos
0.666 0.334 0.000
I05-I09 Chronic rheumatic heart diseases
0.666 0.334 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.666 0.334 0.000
I52 Other heart disorders in diseases classified elsewhere
0.665 0.335 0.000
I48 Atrial fibrillation and flutter
0.665 0.335 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.665 0.335 0.000
I41 Myocarditis in diseases classified elsewhere
0.665 0.335 0.000
I40 Acute myocarditis
0.665 0.335 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.665 0.335 0.000
I37 Pulmonary valve disorders
0.665 0.335 0.000
I36 Nonrheumatic tricuspid valve disorders
0.665 0.335 0.000
I32 Pericarditis in diseases classified elsewhere
0.665 0.335 0.000
R23 Other skin changes
0.665 0.335 0.000
F32.8 Other depressive episodes
0.664 0.336 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.664 0.336 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.664 0.336 0.000
E83 Disorders of mineral metabolism
0.663 0.336 0.000
E10 Insulin-dependent diabetes mellitus
0.663 0.337 0.000
H02.9 Disorder of eyelid, unspecified
0.663 0.337 0.000
K08 Other disorders of teeth and supporting structures
0.663 0.337 0.000
J21 Acute bronchiolitis
0.663 0.337 0.000
K12 Stomatitis and related lesions
0.663 0.337 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.663 0.337 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.663 0.337 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.663 0.337 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.663 0.337 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.663 0.337 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.663 0.337 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.663 0.337 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.663 0.337 0.000
F11 Mental and behavioural disorders due to use of opioids
0.663 0.337 0.000
K04.5 Chronic apical periodontitis
0.662 0.338 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.662 0.338 0.000
H01 Other inflammation of eyelid
0.660 0.340 0.000
D04.7 Skin of lower limb, including hip
0.660 0.340 0.000
E23 Hypofunction and other disorders of pituitary gland
0.660 0.340 0.000
I63 Cerebral infarction
0.660 0.340 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.660 0.340 0.000
R68.8 Other specified general symptoms and signs
0.660 0.340 0.000
Z90.8 Acquired absence of other organs
0.660 0.340 0.000
B44 Aspergillosis
0.660 0.340 0.000
I31 Other diseases of pericardium
0.658 0.341 0.000
S81 Open wound of lower leg
0.658 0.342 0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances
0.657 0.343 0.000
S40-S49 Injuries to the shoulder and upper arm
0.657 0.343 0.000
S82.5 Fracture of medial malleolus
0.657 0.343 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.657 0.343 0.000
Z94 Transplanted organ and tissue status
0.657 0.343 0.000
R60 Oedema, not elsewhere classified
0.656 0.344 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.654 0.345 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.654 0.346 0.000
E34 Other endocrine disorders
0.654 0.346 0.000
E32 Diseases of thymus
0.654 0.346 0.000
E31 Polyglandular dysfunction
0.654 0.346 0.000
E30 Disorders of puberty, not elsewhere classified
0.654 0.346 0.000
E29 Testicular dysfunction
0.654 0.346 0.000
E26 Hyperaldosteronism
0.654 0.346 0.000
E25 Adrenogenital disorders
0.654 0.346 0.000
E24 Cushing's syndrome
0.654 0.346 0.000
E22 Hyperfunction of pituitary gland
0.654 0.346 0.000
E20 Hypoparathyroidism
0.654 0.346 0.000
G40-G47 Episodic and paroxysmal disorders
0.653 0.347 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.653 0.347 0.000
D12.6 Colon, unspecified
0.653 0.347 0.000
S01 Open wound of head
0.653 0.347 0.000
D06 Carcinoma in situ of cervix uteri
0.653 0.347 0.000
R25 Abnormal involuntary movements
0.652 0.347 0.000
K03 Other diseases of hard tissues of teeth
0.651 0.348 0.000
K00 Disorders of tooth development and eruption
0.651 0.348 0.000
Z99.3 Dependence on wheelchair
0.651 0.349 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.651 0.349 0.000
Q28 Other congenital malformations of circulatory system
0.651 0.349 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.650 0.350 0.000
H83 Other diseases of inner ear
0.649 0.351 0.000
Z75 Problems related to medical facilities and other health care
0.649 0.351 0.000
Z72 Problems related to lifestyle
0.648 0.352 0.000
S00 Superficial injury of head
0.647 0.353 0.000
R45 Symptoms and signs involving emotional state
0.647 0.353 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.647 0.353 0.000
Z74 Problems related to care-provider dependency
0.647 0.353 0.000
Q27 Other congenital malformations of peripheral vascular system
0.646 0.354 0.000
J31.0 Chronic rhinitis
0.646 0.354 0.000
K11.6 Mucocele of salivary gland
0.645 0.355 0.000
H80 Otosclerosis
0.645 0.355 0.000
N94.6 Dysmenorrhoea, unspecified
0.645 0.355 0.000
R61.1 Generalised hyperhidrosis
0.645 0.355 0.000
R61.0 Localised hyperhidrosis
0.645 0.355 0.000
N73 Other female pelvic inflammatory diseases
0.644 0.356 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.644 0.356 0.000
K07 Dentofacial anomalies [including malocclusion]
0.644 0.356 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.643 0.356 0.000
Z65 Problems related to other psychosocial circumstances
0.643 0.357 0.000
Z64 Problems related to certain psychosocial circumstances
0.643 0.357 0.000
Z62 Other problems related to upbringing
0.643 0.357 0.000
Z61 Problems related to negative life events in childhood
0.643 0.357 0.000
Z59 Problems related to housing and economic circumstances
0.643 0.357 0.000
Z58 Problems related to physical environment
0.643 0.357 0.000
Z56 Problems related to employment and unemployment
0.643 0.357 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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