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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs34975815
log Bayes Factor = 12.3173
Chromosome 4   position 138,411,388  (GRCh37) Explore rs34975815 on Ensembl!
Variant rs34975815 is part of Cluster X0240

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
I60-I69 Cerebrovascular diseases
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
I10-I15 Hypertensive diseases
0.999 0.001 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.999 0.001 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.998 0.002 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.997 0.003 0.000
G81 Hemiplegia
0.997 0.003 0.000
G81.9 Hemiplegia, unspecified
0.996 0.004 0.000
L50-L54 Urticaria and erythema
0.995 0.005 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.995 0.005 0.000
Chapter V Mental and behavioural disorders
0.995 0.005 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.994 0.006 0.000
I12 Hypertensive renal disease
0.993 0.007 0.000
I69 Sequelae of cerebrovascular disease
0.990 0.010 0.000
R47-R49 Symptoms and signs involving speech and voice
0.989 0.011 0.000
M70-M79 Other soft tissue disorders
0.987 0.013 0.000
I12.0 Hypertensive renal disease with renal failure
0.987 0.013 0.000
R21 Rash and other nonspecific skin eruption
0.986 0.014 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.985 0.015 0.000
R47 Speech disturbances, not elsewhere classified
0.979 0.021 0.000
I10 Essential (primary) hypertension
0.978 0.022 0.000
Chapter XX External causes of morbidity and mortality
0.977 0.023 0.000
I61 Intracerebral haemorrhage
0.977 0.023 0.000
L53 Other erythematous conditions
0.974 0.026 0.000
I67 Other cerebrovascular diseases
0.971 0.029 0.000
R47.0 Dysphasia and aphasia
0.971 0.029 0.000
E00-E07 Disorders of thyroid gland
0.970 0.030 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.970 0.030 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.970 0.030 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.967 0.033 0.000
M75 Shoulder lesions
0.965 0.035 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.965 0.035 0.000
L53.9 Erythematous condition, unspecified
0.959 0.041 0.000
G40-G47 Episodic and paroxysmal disorders
0.953 0.047 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.953 0.047 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.950 0.050 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.947 0.053 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.943 0.057 0.000
I63 Cerebral infarction
0.942 0.058 0.000
Y60.0 During surgical operation
0.939 0.061 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.937 0.063 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.927 0.073 0.000
E20-E35 Disorders of other endocrine glands
0.920 0.080 0.000
R20 Disturbances of skin sensation
0.920 0.080 0.000
M86-M90 Other osteopathies
0.917 0.083 0.000
Y86 Sequelae of other accidents
0.915 0.085 0.000
L50 Urticaria
0.915 0.085 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.910 0.090 0.000
G40 Epilepsy
0.909 0.091 0.000
F80-F89 Disorders of psychological development
0.897 0.103 0.000
L52 Erythema nodosum
0.895 0.105 0.000
I67.9 Cerebrovascular disease, unspecified
0.891 0.109 0.000
Chapter II Neoplasms
0.887 0.113 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.887 0.113 0.000
M75.4 Impingement syndrome of shoulder
0.883 0.117 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.883 0.117 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.883 0.117 0.000
I67.8 Other specified cerebrovascular diseases
0.882 0.118 0.000
E05.9 Thyrotoxicosis, unspecified
0.880 0.120 0.000
M75.0 Adhesive capsulitis of shoulder
0.878 0.122 0.000
I69.3 Sequelae of cerebral infarction
0.878 0.122 0.000
M91-M94 Chondropathies
0.876 0.124 0.000
I61.5 Intracerebral haemorrhage, intraventricular
0.872 0.127 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.872 0.128 0.000
G43 Migraine
0.871 0.129 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.869 0.131 0.000
Chapter VIII Diseases of the ear and mastoid process
0.863 0.137 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.862 0.138 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.857 0.143 0.000
G20-G26 Extrapyramidal and movement disorders
0.854 0.146 0.000
D10-D36 Benign neoplasms
0.853 0.147 0.000
R25 Abnormal involuntary movements
0.851 0.149 0.000
G43.1 Migraine with aura [classical migraine]
0.849 0.151 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.848 0.152 0.000
V20-V29 Motorcycle rider injured in transport accident
0.846 0.154 0.000
R47.8 Other and unspecified speech disturbances
0.844 0.156 0.000
M80-M85 Disorders of bone density and structure
0.844 0.156 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.843 0.157 0.000
D25 Leiomyoma of uterus
0.839 0.161 0.000
L20-L30 Dermatitis and eczema
0.837 0.163 0.000
D23 Other benign neoplasms of skin
0.836 0.164 0.000
M77 Other enthesopathies
0.836 0.164 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.835 0.165 0.000
E21.3 Hyperparathyroidism, unspecified
0.833 0.167 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.832 0.168 0.000
D25.1 Intramural leiomyoma of uterus
0.830 0.170 0.000
L89 Decubitus ulcer
0.830 0.170 0.000
D23.7 Skin of lower limb, including hip
0.824 0.176 0.000
G82 Paraplegia and tetraplegia
0.823 0.177 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.820 0.180 0.000
M75.9 Shoulder lesion, unspecified
0.819 0.180 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.819 0.181 0.000
I67.1 Cerebral aneurysm, nonruptured
0.818 0.182 0.000
M00-M03 Infectious arthropathies
0.816 0.184 0.000
R20.8 Other and unspecified disturbances of skin sensation
0.815 0.185 0.000
M94 Other disorders of cartilage
0.814 0.185 0.000
F80 Specific developmental disorders of speech and language
0.811 0.189 0.000
Y85 Sequelae of transport accidents
0.811 0.189 0.000
I12.9 Hypertensive renal disease without renal failure
0.811 0.189 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.810 0.190 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.809 0.191 0.000
G11 Hereditary ataxia
0.808 0.192 0.000
I61.9 Intracerebral haemorrhage, unspecified
0.808 0.192 0.000
G70-G73 Diseases of myoneural junction and muscle
0.808 0.192 0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.807 0.193 0.000
F20 Schizophrenia
0.806 0.194 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.803 0.197 0.000
Y65 Other misadventures during surgical and medical care
0.801 0.199 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.801 0.199 0.000
L51 Erythema multiforme
0.801 0.199 0.000
M86 Osteomyelitis
0.800 0.200 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.800 0.200 0.000
I15 Secondary hypertension
0.799 0.201 0.000
G30-G32 Other degenerative diseases of the nervous system
0.799 0.201 0.000
I61.8 Other intracerebral haemorrhage
0.794 0.206 0.000
G83 Other paralytic syndromes
0.793 0.207 0.000
M75.5 Bursitis of shoulder
0.793 0.207 0.000
D23.5 Skin of trunk
0.793 0.207 0.000
R49 Voice disturbances
0.792 0.208 0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.788 0.212 0.000
C71 Malignant neoplasm of brain
0.787 0.213 0.000
F29 Unspecified nonorganic psychosis
0.787 0.213 0.000
I61.4 Intracerebral haemorrhage in cerebellum
0.786 0.214 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.785 0.215 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.781 0.219 0.000
C69 Malignant neoplasm of eye and adnexa
0.781 0.219 0.000
M50-M54 Other dorsopathies
0.780 0.220 0.000
C83.3 Large cell (diffuse)
0.779 0.221 0.000
W20-W49 Exposure to inanimate mechanical forces
0.777 0.223 0.000
E22 Hyperfunction of pituitary gland
0.777 0.223 0.000
X20-X29 Contact with venomous animals and plants
0.777 0.223 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.773 0.226 0.000
D27 Benign neoplasm of ovary
0.773 0.227 0.000
R20.0 Anaesthesia of skin
0.773 0.227 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.772 0.228 0.000
D25.2 Subserosal leiomyoma of uterus
0.772 0.228 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.771 0.229 0.000
M79.2 Neuralgia and neuritis, unspecified
0.769 0.231 0.000
F01 Vascular dementia
0.769 0.231 0.000
M89 Other disorders of bone
0.769 0.231 0.000
Q60-Q64 Congenital malformations of the urinary system
0.769 0.231 0.000
Q50-Q56 Congenital malformations of genital organs
0.768 0.232 0.000
M71 Other bursopathies
0.763 0.237 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.762 0.238 0.000
M40-M43 Deforming dorsopathies
0.759 0.241 0.000
L50.9 Urticaria, unspecified
0.758 0.242 0.000
M72 Fibroblastic disorders
0.757 0.243 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.755 0.245 0.000
R27 Other lack of coordination
0.755 0.245 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.754 0.246 0.000
R25.8 Other and unspecified abnormal involuntary movements
0.754 0.246 0.000
R50-R69 General symptoms and signs
0.753 0.247 0.000
L50.1 Idiopathic urticaria
0.752 0.248 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.751 0.249 0.000
F03 Unspecified dementia
0.751 0.249 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.750 0.250 0.000
F80.1 Expressive language disorder
0.750 0.250 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.750 0.250 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.749 0.251 0.000
M79.0 Rheumatism, unspecified
0.749 0.251 0.000
Chapter I Certain infectious and parasitic diseases
0.748 0.252 0.000
X00-X09 Exposure to smoke, fire and flames
0.747 0.253 0.000
L98.8 Other specified disorders of skin and subcutaneous tissue
0.746 0.254 0.000
I60 Subarachnoid haemorrhage
0.746 0.254 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.745 0.255 0.000
D46 Myelodysplastic syndromes
0.744 0.256 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.744 0.256 0.000
M87 Osteonecrosis
0.743 0.257 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.743 0.257 0.000
M85 Other disorders of bone density and structure
0.742 0.258 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.739 0.261 0.000
C83.0 Small cell (diffuse)
0.738 0.262 0.000
M94.2 Chondromalacia
0.737 0.263 0.000
L89.9 Decubitus ulcer and pressure area, unspecified
0.737 0.263 0.000
L95.9 Vasculitis limited to skin, unspecified
0.736 0.264 0.000
R60 Oedema, not elsewhere classified
0.735 0.265 0.000
F10.0 Acute intoxication
0.735 0.265 0.000
E50-E64 Other nutritional deficiencies
0.734 0.266 0.000
X50-X57 Overexertion, travel and privation
0.733 0.267 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.733 0.267 0.000
H65-H75 Diseases of middle ear and mastoid
0.733 0.267 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.731 0.269 0.000
E34 Other endocrine disorders
0.730 0.270 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.729 0.271 0.000
R54 Senility
0.728 0.272 0.000
F23 Acute and transient psychotic disorders
0.728 0.272 0.000
E40-E46 Malnutrition
0.727 0.273 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.727 0.273 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.727 0.273 0.000
L50.0 Allergic urticaria
0.726 0.274 0.000
F02 Dementia in other diseases classified elsewhere
0.726 0.274 0.000
B95-B98 Bacterial, viral and other infectious agents
0.726 0.274 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.726 0.274 0.000
E70-E90 Metabolic disorders
0.726 0.274 0.000
L89.0 Stage I decubitus ulcer and pressure area
0.725 0.275 0.000
C71.2 Temporal lobe
0.723 0.277 0.000
L10-L14 Bullous disorders
0.723 0.277 0.000
R20.1 Hypoaesthesia of skin
0.722 0.278 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.721 0.279 0.000
R43 Disturbances of smell and taste
0.720 0.280 0.000
Y89 Sequelae of other external causes
0.720 0.280 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.720 0.280 0.000
G25 Other extrapyramidal and movement disorders
0.719 0.281 0.000
G11.9 Hereditary ataxia, unspecified
0.717 0.283 0.000
E23 Hypofunction and other disorders of pituitary gland
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.717 0.283 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.717 0.283 0.000
I13 Hypertensive heart and renal disease
0.717 0.283 0.000
C91 Lymphoid leukaemia
0.716 0.284 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.716 0.284 0.000
M60-M63 Disorders of muscles
0.715 0.285 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.715 0.285 0.000
D17 Benign lipomatous neoplasm
0.715 0.285 0.000
G81.1 Spastic hemiplegia
0.715 0.285 0.000
G81.0 Flaccid hemiplegia
0.715 0.285 0.000
L54 Erythema in diseases classified elsewhere
0.713 0.286 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.713 0.287 0.000
F70-F79 Mental retardation
0.713 0.287 0.000
R94 Abnormal results of function studies
0.713 0.287 0.000
D23.4 Skin of scalp and neck
0.713 0.287 0.000
M75.1 Rotator cuff syndrome
0.713 0.287 0.000
R68 Other general symptoms and signs
0.712 0.288 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.711 0.289 0.000
R44.3 Hallucinations, unspecified
0.711 0.289 0.000
L30 Other dermatitis
0.710 0.290 0.000
L88 Pyoderma gangrenosum
0.710 0.290 0.000
D46.9 Myelodysplastic syndrome, unspecified
0.710 0.290 0.000
I85 Oesophageal varices
0.710 0.290 0.000
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified
0.709 0.291 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.708 0.292 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.707 0.293 0.000
L50.8 Other urticaria
0.707 0.293 0.000
G40.5 Special epileptic syndromes
0.707 0.293 0.000
R60.0 Localised oedema
0.705 0.295 0.000
L93 Lupus erythematosus
0.704 0.296 0.000
G90-G99 Other disorders of the nervous system
0.704 0.296 0.000
H90-H95 Other disorders of ear
0.703 0.297 0.000
M86.9 Osteomyelitis, unspecified
0.703 0.297 0.000
L53.8 Other specified erythematous conditions
0.702 0.298 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.702 0.298 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.701 0.299 0.000
Y35-Y36 Legal intervention and operations of war
0.701 0.299 0.000
Y10-Y34 Event of undetermined intent
0.701 0.299 0.000
Y00-Y09 Assault
0.701 0.299 0.000
X85-X99 Assault
0.701 0.299 0.000
X30-X39 Exposure to forces of nature
0.701 0.299 0.000
X10-X19 Contact with heat and hot substances
0.701 0.299 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.701 0.299 0.000
W75-W84 Other accidental threats to breathing
0.701 0.299 0.000
W65-W74 Accidental drowning and submersion
0.701 0.299 0.000
V98-V99 Other and unspecified transport accidents
0.701 0.299 0.000
V95-V97 Air and space transport accidents
0.701 0.299 0.000
V90-V94 Water transport accidents
0.701 0.299 0.000
V70-V79 Bus occupant injured in transport accident
0.701 0.299 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.701 0.299 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.701 0.299 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.701 0.299 0.000
V01-V09 Pedestrian injured in transport accident
0.701 0.299 0.000
I61.6 Intracerebral haemorrhage, multiple localised
0.700 0.300 0.000
I61.3 Intracerebral haemorrhage in brain stem
0.700 0.300 0.000
V23 Motorcycle rider injured in collision with car, pick-up truck or van
0.700 0.300 0.000
M75.2 Bicipital tendinitis
0.700 0.300 0.000
G20 Parkinson's disease
0.699 0.301 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.699 0.301 0.000
L53.3 Other chronic figurate erythema
0.699 0.301 0.000
L53.2 Erythema marginatum
0.699 0.301 0.000
L53.1 Erythema annulare centrifugum
0.699 0.301 0.000
L53.0 Toxic erythema
0.699 0.301 0.000
Q80-Q89 Other congenital malformations
0.698 0.302 0.000
F25 Schizoaffective disorders
0.697 0.303 0.000
L60-L75 Disorders of skin appendages
0.697 0.303 0.000
M80 Osteoporosis with pathological fracture
0.697 0.303 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.696 0.304 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.696 0.304 0.000
I67.5 Moyamoya disease
0.696 0.304 0.000
I67.4 Hypertensive encephalopathy
0.696 0.304 0.000
I67.3 Progressive vascular leukoencephalopathy
0.696 0.304 0.000
H66 Suppurative and unspecified otitis media
0.696 0.304 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.696 0.304 0.000
E00 Congenital iodine-deficiency syndrome
0.696 0.304 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.696 0.304 0.000
E05.8 Other thyrotoxicosis
0.695 0.305 0.000
E05.5 Thyroid crisis or storm
0.695 0.305 0.000
E05.4 Thyrotoxicosis factitia
0.695 0.305 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.695 0.305 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.695 0.305 0.000
M50 Cervical disk disorders
0.695 0.305 0.000
D29 Benign neoplasm of male genital organs
0.694 0.306 0.000
D17.0 Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck
0.694 0.306 0.000
E20 Hypoparathyroidism
0.694 0.306 0.000
G41 Status epilepticus
0.693 0.307 0.000
C69.3 Choroid
0.693 0.307 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.693 0.307 0.000
Y88 Sequelae of surgical and medical care as external cause
0.693 0.307 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.693 0.307 0.000
M75.8 Other shoulder lesions
0.692 0.308 0.000
Y64 Contaminated medical or biological substances
0.692 0.308 0.000
Y63 Failure in dosage during surgical and medical care
0.692 0.308 0.000
Y62 Failure of sterile precautions during surgical and medical care
0.692 0.308 0.000
Y61 Foreign object accidentally left in body during surgical and medical care
0.692 0.308 0.000
Y69 Unspecified misadventure during surgical and medical care
0.692 0.308 0.000
Y66 Nonadministration of surgical and medical care
0.692 0.308 0.000
Y85.0 Sequelae of motor-vehicle accident
0.691 0.309 0.000
F81 Specific developmental disorders of scholastic skills
0.690 0.310 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.689 0.311 0.000
R26 Abnormalities of gait and mobility
0.689 0.311 0.000
I98.2 Oesophageal varices in diseases classified elsewhere
0.688 0.312 0.000
G40.8 Other epilepsy
0.687 0.313 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.685 0.315 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.685 0.315 0.000
I11 Hypertensive heart disease
0.684 0.316 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.683 0.316 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.683 0.316 0.000
R49.0 Dysphonia
0.683 0.317 0.000
G82.5 Tetraplegia, unspecified
0.683 0.317 0.000
M94.26 Chondromalacia (Lower leg)
0.682 0.318 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.681 0.319 0.000
Y60.9 During unspecified surgical and medical care
0.681 0.319 0.000
Y60.8 During other surgical and medical care
0.681 0.319 0.000
Y60.7 During administration of enema
0.681 0.319 0.000
Y60.6 During aspiration, puncture and other catheterisation
0.681 0.319 0.000
Y60.5 During heart catheterisation
0.681 0.319 0.000
Y60.4 During endoscopic examination
0.681 0.319 0.000
Y60.3 During injection or immunisation
0.681 0.319 0.000
Y60.2 During kidney dialysis or other perfusion
0.681 0.319 0.000
Y60.1 During infusion or transfusion
0.681 0.319 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.680 0.320 0.000
E28 Ovarian dysfunction
0.680 0.320 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.680 0.320 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.679 0.321 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.679 0.321 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.679 0.321 0.000
Q35-Q37 Cleft lip and cleft palate
0.679 0.321 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.679 0.321 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.678 0.322 0.000
M79.26 Neuralgia and neuritis, unspecified (Lower leg)
0.678 0.322 0.000
F60-F69 Disorders of adult personality and behaviour
0.676 0.324 0.000
F09 Unspecified organic or symptomatic mental disorder
0.676 0.324 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.676 0.324 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.676 0.324 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.676 0.324 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.676 0.324 0.000
I62 Other nontraumatic intracranial haemorrhage
0.674 0.326 0.000
F10.3 Withdrawal state
0.673 0.327 0.000
I82 Other venous embolism and thrombosis
0.673 0.327 0.000
M94.8 Other specified disorders of cartilage
0.673 0.327 0.000
F41 Other anxiety disorders
0.671 0.329 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.671 0.329 0.000
R27.0 Ataxia, unspecified
0.670 0.330 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.670 0.330 0.000
R23 Other skin changes
0.670 0.330 0.000
R25.1 Tremor, unspecified
0.670 0.330 0.000
M79.00 Rheumatism, unspecified (Multiple sites)
0.670 0.330 0.000
L83 Acanthosis nigricans
0.670 0.330 0.000
M77.0 Medial epicondylitis
0.669 0.330 0.000
C82.3 Follicular lymphoma grade IIIa
0.669 0.331 0.000
F20.0 Paranoid schizophrenia
0.669 0.331 0.000
M85.8 Other specified disorders of bone density and structure
0.669 0.331 0.000
E22.0 Acromegaly and pituitary gigantism
0.669 0.331 0.000
M79.28 Neuralgia and neuritis, unspecified (Other)
0.668 0.332 0.000
F30-F39 Mood [affective] disorders
0.668 0.332 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.667 0.333 0.000
G11.4 Hereditary spastic paraplegia
0.667 0.333 0.000
L51.1 Bullous erythema multiforme
0.667 0.333 0.000
M50.2 Other cervical disk displacement
0.666 0.334 0.000
R42 Dizziness and giddiness
0.666 0.334 0.000
C82.2 Large cell, follicular
0.665 0.335 0.000
G72 Other myopathies
0.665 0.335 0.000
F28 Other nonorganic psychotic disorders
0.665 0.335 0.000
F24 Induced delusional disorder
0.665 0.335 0.000
F21 Schizotypal disorder
0.665 0.335 0.000
D34 Benign neoplasm of thyroid gland
0.664 0.336 0.000
M72.2 Plantar fascial fibromatosis
0.664 0.336 0.000
R68.8 Other specified general symptoms and signs
0.663 0.337 0.000
L80 Vitiligo
0.662 0.338 0.000
M00 Pyogenic arthritis
0.662 0.338 0.000
E83 Disorders of mineral metabolism
0.662 0.338 0.000
Y65.8 Other specified misadventures during surgical and medical care
0.661 0.339 0.000
F20.9 Schizophrenia, unspecified
0.660 0.340 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.659 0.340 0.000
E32 Diseases of thymus
0.659 0.340 0.000
E31 Polyglandular dysfunction
0.659 0.340 0.000
E30 Disorders of puberty, not elsewhere classified
0.659 0.340 0.000
E26 Hyperaldosteronism
0.659 0.340 0.000
E25 Adrenogenital disorders
0.659 0.340 0.000
R20.3 Hyperaesthesia
0.659 0.341 0.000
V80-V89 Other land transport accidents
0.658 0.341 0.000
M88 Paget's disease of bone [osteitis deformans]
0.658 0.342 0.000
M76 Enthesopathies of lower limb, excluding foot
0.657 0.342 0.000
L50.6 Contact urticaria
0.656 0.344 0.000
L50.5 Cholinergic urticaria
0.656 0.344 0.000
L50.4 Vibratory urticaria
0.656 0.344 0.000
L50.3 Dermatographic urticaria
0.656 0.344 0.000
L50.2 Urticaria due to cold and heat
0.656 0.344 0.000
F99-F99 Unspecified mental disorder
0.655 0.345 0.000
R94.3 Abnormal results of cardiovascular function studies
0.655 0.345 0.000
H60-H62 Diseases of external ear
0.655 0.345 0.000
R46 Symptoms and signs involving appearance and behaviour
0.654 0.346 0.000
G80 Infantile cerebral palsy
0.654 0.346 0.000
V28 Motorcycle rider injured in noncollision transport accident
0.654 0.346 0.000
W50-W64 Exposure to animate mechanical forces
0.654 0.346 0.000
C81 Hodgkin's disease
0.653 0.347 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.653 0.347 0.000
L94 Other localised connective tissue disorders
0.653 0.347 0.000
L87 Transepidermal elimination disorders
0.653 0.347 0.000
L86 Keratoderma in diseases classified elsewhere
0.653 0.347 0.000
G25.8 Other specified extrapyramidal and movement disorders
0.653 0.347 0.000
F06.7 Mild cognitive disorder
0.652 0.348 0.000
V27 Motorcycle rider injured in collision with fixed or stationary object
0.652 0.348 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.652 0.348 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.652 0.348 0.000
H65 Nonsuppurative otitis media
0.651 0.349 0.000
L28 Lichen simplex chronicus and prurigo
0.650 0.350 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.649 0.351 0.000
W22 Striking against or struck by other objects
0.649 0.351 0.000
C82.0 Small cleaved cell, follicular
0.648 0.352 0.000
M77.4 Metatarsalgia
0.645 0.355 0.000
R60.1 Generalised oedema
0.644 0.356 0.000
C64-C68 Malignant neoplasms of urinary tract
0.644 0.356 0.000
F01.9 Vascular dementia, unspecified
0.644 0.356 0.000
R25.3 Fasciculation
0.644 0.356 0.000
C92 Myeloid leukaemia
0.644 0.356 0.000
F84 Pervasive developmental disorders
0.643 0.357 0.000
F89 Unspecified disorder of psychological development
0.643 0.357 0.000
F88 Other disorders of psychological development
0.643 0.357 0.000
F83 Mixed specific developmental disorders
0.643 0.357 0.000
F82 Specific developmental disorder of motor function
0.643 0.357 0.000
C69.9 Eye, unspecified
0.643 0.357 0.000
Q66 Congenital deformities of feet
0.643 0.357 0.000
M77.5 Other enthesopathy of foot
0.643 0.357 0.000
I86 Varicose veins of other sites
0.641 0.359 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.641 0.359 0.000
L98.1 Factitial dermatitis
0.640 0.360 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.640 0.360 0.000
M92 Other juvenile osteochondrosis
0.640 0.360 0.000
F00 Dementia in Alzheimer's disease
0.640 0.360 0.000
L89.3 Stage IV decubitus ulcer
0.639 0.360 0.000
C82.1 Mixed small cleaved and large cell, follicular
0.638 0.361 0.000
I15.9 Seconday hypertension, unspecified
0.638 0.362 0.000
M89.8 Other specified disorders of bone
0.636 0.364 0.000
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere
0.636 0.364 0.000
G14 Postpolio syndrome
0.636 0.364 0.000
G10 Huntington's disease
0.636 0.364 0.000
D30 Benign neoplasm of urinary organs
0.635 0.365 0.000
R56 Convulsions, not elsewhere classified
0.635 0.365 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.634 0.366 0.000
F22 Persistent delusional disorders
0.633 0.366 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.633 0.367 0.000
C95 Leukaemia of unspecified cell type
0.633 0.367 0.000
C94 Other leukaemias of specified cell type
0.633 0.367 0.000
C93 Monocytic leukaemia
0.633 0.367 0.000
C86 Other specified types of T/NK-cell lymphoma
0.633 0.367 0.000
I85.9 Oesophageal varices without bleeding
0.633 0.367 0.000
X23 Contact with hornets, wasps and bees
0.633 0.367 0.000
R26.3 Immobility
0.631 0.369 0.000
E89.0 Postprocedural hypothyroidism
0.631 0.369 0.000
C88 Malignant immunoproliferative diseases
0.630 0.369 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.630 0.370 0.000
E65-E68 Obesity and other hyperalimentation
0.630 0.370 0.000
M43 Other deforming dorsopathies
0.629 0.371 0.000
M91 Juvenile osteochondrosis of hip and pelvis
0.628 0.372 0.000
G82.1 Spastic paraplegia
0.628 0.372 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.627 0.372 0.000
G12 Spinal muscular atrophy and related syndromes
0.627 0.373 0.000
G43.3 Complicated migraine
0.625 0.375 0.000
G43.2 Status migrainosus
0.625 0.375 0.000
G43.0 Migraine without aura [common migraine]
0.625 0.375 0.000
M89.0 Algoneurodystrophy
0.624 0.376 0.000
M02 Reactive arthropathies
0.624 0.376 0.000
M05-M14 Inflammatory polyarthropathies
0.623 0.377 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.623 0.377 0.000
E21.4 Other specified disorders of parathyroid gland
0.623 0.377 0.000
E21.2 Other hyperparathyroidism
0.623 0.377 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.623 0.377 0.000
W25 Contact with sharp glass
0.620 0.379 0.000
F07.2 Postconcussional syndrome
0.620 0.380 0.000
L85 Other epidermal thickening
0.620 0.380 0.000
Q76 Congenital malformations of spine and bony thorax
0.620 0.380 0.000
C71.8 Overlapping lesion of brain
0.620 0.380 0.000
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs
0.620 0.380 0.000
W23 Caught, crushed, jammed or pinched in or between objects
0.619 0.381 0.000
D31 Benign neoplasm of eye and adnexa
0.619 0.381 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.619 0.381 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.618 0.382 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.618 0.382 0.000
H92 Otalgia and effusion of ear
0.618 0.382 0.000
G83.8 Other specified paralytic syndromes
0.618 0.382 0.000
Y85.9 Sequelae of other and unspecified transport accidents
0.618 0.382 0.000
M65-M68 Disorders of synovium and tendon
0.618 0.382 0.000
G44 Other headache syndromes
0.617 0.383 0.000
M82 Osteoporosis in diseases classified elsewhere
0.617 0.383 0.000
R25.2 Cramp and spasm
0.616 0.384 0.000
E21.0 Primary hyperparathyroidism
0.616 0.384 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.616 0.384 0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)
0.616 0.384 0.000
L60 Nail disorders
0.615 0.385 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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