TreeWAS – Variant ID: rs35107139

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
D12 Benign neoplasm of colon, rectum, anus and anal canal	1.000	0.000	0.000
D12.3 Transverse colon	1.000	0.000	0.000
D12.0 Caecum	0.998	0.002	0.000
D12.6 Colon, unspecified	0.994	0.006	0.000
D12.8 Rectum	0.977	0.023	0.000
D12.4 Descending colon	0.953	0.047	0.000
D12.5 Sigmoid colon	0.884	0.116	0.000
D12.9 Anus and anal canal	0.868	0.132	0.000
D12.1 Appendix	0.618	0.382	0.000
D12.2 Ascending colon	0.614	0.386	0.000
K76.9 Liver disease, unspecified	0.228	0.772	0.000
K76.6 Portal hypertension	0.227	0.773	0.000
K76 Other diseases of liver	0.226	0.774	0.000
K70-K77 Diseases of liver	0.218	0.782	0.000
K70 Alcoholic liver disease	0.216	0.784	0.000
K74 Fibrosis and cirrhosis of liver	0.211	0.789	0.000
K70.3 Alcoholic cirrhosis of liver	0.207	0.793	0.000
K74.0 Hepatic fibrosis	0.194	0.806	0.000
K70.1 Alcoholic hepatitis	0.192	0.808	0.000
K74.6 Other and unspecified cirrhosis of liver	0.190	0.810	0.000
K72 Hepatic failure, not elsewhere classified	0.180	0.820	0.000
K70.4 Alcoholic hepatic failure	0.179	0.821	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.168	0.832	0.000
K77 Liver disorders in diseases classified elsewhere	0.166	0.834	0.000
K76.1 Chronic passive congestion of liver	0.164	0.836	0.000
K72.0 Acute and subacute hepatic failure	0.163	0.837	0.000
K76.5 Hepatic veno-occlusive disease	0.162	0.838	0.000
K76.4 Peliosis hepatis	0.162	0.838	0.000
K76.3 Infarction of liver	0.162	0.838	0.000
K76.2 Central haemorrhagic necrosis of liver	0.162	0.838	0.000
K74.3 Primary biliary cirrhosis	0.159	0.841	0.000
K74.1 Hepatic sclerosis	0.153	0.847	0.000
K74.4 Secondary biliary cirrhosis	0.152	0.848	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.152	0.848	0.000
K74.5 Biliary cirrhosis, unspecified	0.149	0.851	0.000
K70.9 Alcoholic liver disease, unspecified	0.147	0.853	0.000
D12.7 Rectosigmoid junction	0.145	0.855	0.001
K71 Toxic liver disease	0.137	0.863	0.000
K72.1 Chronic hepatic failure	0.135	0.865	0.000
K77.8 Liver disorders in other diseases classified elsewhere	0.128	0.872	0.000
K70.0 Alcoholic fatty liver	0.121	0.878	0.000
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.119	0.881	0.000
K76.0 Fatty (change of) liver, not elsewhere classified	0.114	0.886	0.000
K76.7 Hepatorenal syndrome	0.114	0.886	0.000
K73 Chronic hepatitis, not elsewhere classified	0.105	0.895	0.000
K71.9 Toxic liver disease, unspecified	0.098	0.901	0.000
K71.8 Toxic liver disease with other disorders of liver	0.098	0.901	0.000
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.098	0.901	0.000
K71.5 Toxic liver disease with chronic active hepatitis	0.098	0.901	0.000
K71.4 Toxic liver disease with chronic lobular hepatitis	0.098	0.901	0.000
K71.3 Toxic liver disease with chronic persistent hepatitis	0.098	0.901	0.000
K71.2 Toxic liver disease with acute hepatitis	0.098	0.901	0.000
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.098	0.902	0.000
K71.1 Toxic liver disease with hepatic necrosis	0.094	0.905	0.000
K31.7 Polyp of stomach and duodenum	0.091	0.909	0.000
K72.9 Hepatic failure, unspecified	0.089	0.911	0.000
K71.0 Toxic liver disease with cholestasis	0.085	0.914	0.000
K75 Other inflammatory liver diseases	0.077	0.923	0.000
K73.8 Other chronic hepatitis, not elsewhere classified	0.076	0.924	0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.075	0.924	0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.075	0.924	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.071	0.929	0.000
K75.2 Nonspecific reactive hepatitis	0.056	0.944	0.000
K75.1 Phlebitis of portal vein	0.056	0.944	0.000
K75.8 Other specified inflammatory liver diseases	0.056	0.944	0.000
K75.0 Abscess of liver	0.051	0.949	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.050	0.950	0.000
K75.4 Autoimmune hepatitis	0.041	0.959	0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.040	0.960	0.000
K75.9 Inflammatory liver disease, unspecified	0.037	0.963	0.000
K73.9 Chronic hepatitis, unspecified	0.033	0.966	0.001
C18.0 Caecum	0.027	0.973	0.000
C18.2 Ascending colon	0.027	0.973	0.000
M34.9 Systemic sclerosis, unspecified	0.026	0.974	0.000
C18 Malignant neoplasm of colon	0.026	0.974	0.000
C18.1 Appendix	0.022	0.978	0.000
K76.8 Other specified diseases of liver	0.022	0.978	0.000
C18.4 Transverse colon	0.021	0.979	0.000
H72 Perforation of tympanic membrane	0.021	0.979	0.000
H72.0 Central perforation of tympanic membrane	0.020	0.980	0.000
C18.3 Hepatic flexure	0.020	0.980	0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.020	0.980	0.000
C18.6 Descending colon	0.020	0.980	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.020	0.980	0.000
C18.5 Splenic flexure	0.019	0.981	0.000
H65-H75 Diseases of middle ear and mastoid	0.019	0.981	0.000
J39.8 Other specified diseases of upper respiratory tract	0.018	0.982	0.000
H72.2 Other marginal perforations of tympanic membrane	0.018	0.982	0.000
H74.4 Polyp of middle ear	0.017	0.983	0.000
H74 Other disorders of middle ear and mastoid	0.017	0.983	0.000
H70 Mastoiditis and related conditions	0.017	0.983	0.000
R09.2 Respiratory arrest	0.000	0.984	0.016
M34 Systemic sclerosis	0.016	0.984	0.000
K63.5 Polyp of colon	0.016	0.984	0.000
H72.1 Attic perforation of tympanic membrane	0.015	0.985	0.000
H68 Eustachian salpingitis and obstruction	0.015	0.985	0.000
M25.51 Pain in joint (Shoulder region)	0.000	0.985	0.015
C15-C26 Malignant neoplasms of digestive organs	0.014	0.986	0.000
C19 Malignant neoplasm of rectosigmoid junction	0.014	0.986	0.000
C18.8 Overlapping lesion of colon	0.014	0.986	0.000
H74.0 Tympanosclerosis	0.014	0.986	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.014	0.986	0.000
M34.8 Other forms of systemic sclerosis	0.014	0.986	0.000
H70.0 Acute mastoiditis	0.014	0.986	0.000
H73 Other disorders of tympanic membrane	0.014	0.986	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.014	0.986	0.000
H67 Otitis media in diseases classified elsewhere	0.014	0.986	0.000
H71 Cholesteatoma of middle ear	0.014	0.986	0.000
H95.1 Other disorders following mastoidectomy	0.014	0.986	0.000
C20 Malignant neoplasm of rectum	0.013	0.987	0.000
C25 Malignant neoplasm of pancreas	0.013	0.987	0.000
H70.9 Mastoiditis, unspecified	0.013	0.987	0.000
M34.1 CR(E)ST syndrome	0.013	0.987	0.000
H70.1 Chronic mastoiditis	0.013	0.987	0.000
H66 Suppurative and unspecified otitis media	0.013	0.987	0.000
H69 Other disorders of Eustachian tube	0.013	0.987	0.000
Chapter VIII Diseases of the ear and mastoid process	0.013	0.987	0.000
H90-H95 Other disorders of ear	0.013	0.987	0.000
S01.8 Open wound of other parts of head	0.013	0.987	0.000
H70.8 Other mastoiditis and related conditions	0.013	0.987	0.000
C17 Malignant neoplasm of small intestine	0.013	0.987	0.000
H68.1 Obstruction of Eustachian tube	0.012	0.987	0.000
H74.1 Adhesive middle ear disease	0.012	0.988	0.000
C17.2 Ileum	0.012	0.988	0.000
H70.2 Petrositis	0.012	0.988	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.012	0.988	0.000
C18.9 Colon, unspecified	0.012	0.988	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.012	0.988	0.000
C25.4 Endocrine pancreas	0.012	0.988	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.012	0.988	0.000
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity	0.012	0.988	0.000
H95.9 Postprocedural disorder of ear and mastoid process, unspecified	0.011	0.989	0.000
C25.1 Body of pancreas	0.011	0.989	0.000
R82.9 Other and unspecified abnormal finding in urine	0.000	0.989	0.011
H73.9 Disorder of tympanic membrane, unspecified	0.011	0.989	0.000
H66.4 Suppurative otitis media, unspecified	0.011	0.989	0.000
H68.0 Eustachian salpingitis	0.011	0.989	0.000
M34.0 Progressive systemic sclerosis	0.011	0.989	0.000
C25.2 Tail of pancreas	0.011	0.989	0.000
H73.0 Acute myringitis	0.011	0.989	0.000
C17.1 Jejunum	0.011	0.989	0.000
H95.8 Other postprocedural disorders of ear and mastoid process	0.011	0.989	0.000
H73.1 Chronic myringitis	0.011	0.989	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.011	0.989	0.000
C25.3 Pancreatic duct	0.011	0.989	0.000
H66.0 Acute suppurative otitis media	0.011	0.989	0.000
H69.8 Other specified disorders of Eustachian tube	0.010	0.989	0.000
L91.8 Other hypertrophic disorders of skin	0.011	0.989	0.000
S02.60 Fracture of mandible (closed)	0.010	0.990	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.010	0.990	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.010	0.990	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.010	0.990	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.010	0.990	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.010	0.990	0.000
H93 Other disorders of ear, not elsewhere classified	0.010	0.990	0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.010	0.990	0.000
H92 Otalgia and effusion of ear	0.010	0.990	0.000
H92.1 Otorrhoea	0.010	0.990	0.000
C25.7 Other parts of pancreas	0.010	0.990	0.000
H66.9 Otitis media, unspecified	0.010	0.990	0.000
H80-H83 Diseases of inner ear	0.010	0.990	0.000
H69.0 Patulous Eustachian tube	0.010	0.990	0.000
C25.9 Pancreas, unspecified	0.010	0.990	0.000
H94 Other disorders of ear in diseases classified elsewhere	0.009	0.990	0.000
S01.0 Open wound of scalp	0.010	0.990	0.000
C23 Malignant neoplasm of gallbladder	0.009	0.991	0.000
H93.8 Other specified disorders of ear	0.009	0.991	0.000
C17.8 Overlapping lesion of small intestine	0.009	0.991	0.000
C17.3 Meckel's diverticulum	0.009	0.991	0.000
S01 Open wound of head	0.009	0.991	0.000
H81.0 Meniere's disease	0.009	0.991	0.000
C25.8 Overlapping lesion of pancreas	0.009	0.991	0.000
C26 Malignant neoplasm of other and ill-defined digestive organs	0.009	0.991	0.000
H81 Disorders of vestibular function	0.009	0.991	0.000
S02.6 Fracture of mandible	0.009	0.991	0.000
C21 Malignant neoplasm of anus and anal canal	0.009	0.991	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.009	0.991	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.009	0.991	0.000
S01.2 Open wound of nose	0.009	0.991	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.008	0.992	0.000
H60-H62 Diseases of external ear	0.008	0.992	0.000
H90 Conductive and sensorineural hearing loss	0.008	0.992	0.000
H66.3 Other chronic suppurative otitis media	0.008	0.992	0.000
T78.2 Anaphylactic shock, unspecified	0.008	0.992	0.000
C25.0 Head of pancreas	0.008	0.992	0.000
H69.9 Eustachian tube disorder, unspecified	0.008	0.992	0.000
C24.9 Biliary tract, unspecified	0.008	0.992	0.000
S02 Fracture of skull and facial bones	0.008	0.992	0.000
H91 Other hearing loss	0.008	0.992	0.000
H65 Nonsuppurative otitis media	0.008	0.992	0.000
J39 Other diseases of upper respiratory tract	0.008	0.992	0.000
H93.0 Degenerative and vascular disorders of ear	0.007	0.992	0.000
S02.9 Fracture of skull and facial bones, part unspecified	0.007	0.992	0.000
C24.8 Overlapping lesion of biliary tract	0.007	0.993	0.000
H90.2 Conductive hearing loss, unspecified	0.007	0.993	0.000
H93.2 Other abnormal auditory perceptions	0.007	0.993	0.000
H60 Otitis externa	0.007	0.993	0.000
H82 Vertiginous syndromes in diseases classified elsewhere	0.007	0.993	0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.007	0.993	0.000
S02.90 Fracture of skull and facial bones, part unspecified (closed)	0.007	0.993	0.000
C21.8 Overlapping lesion of rectum, anus and anal canal	0.007	0.993	0.000
C24.1 Ampulla of Vater	0.007	0.993	0.000
H94.8 Other specified disorders of ear in diseases classified elsewhere	0.007	0.993	0.000
H94.0 Acoustic neuritis in infectious and parasitic diseases classified elsewhere	0.007	0.993	0.000
H80 Otosclerosis	0.007	0.993	0.000
T78 Adverse effects, not elsewhere classified	0.007	0.993	0.000
C17.9 Small intestine, unspecified	0.007	0.993	0.000
H81.3 Other peripheral vertigo	0.007	0.993	0.000
S00-S09 Injuries to the head	0.007	0.993	0.000
H93.9 Disorder of ear, unspecified	0.007	0.993	0.000
C26.9 Ill-defined sites within the digestive system	0.007	0.993	0.000
H91.2 Sudden idiopathic hearing loss	0.007	0.993	0.000
H92.2 Otorrhagia	0.007	0.993	0.000
H81.8 Other disorders of vestibular function	0.007	0.993	0.000
S02.7 Multiple fractures involving skull and facial bones	0.007	0.993	0.000
C26.8 Overlapping lesion of digestive system	0.007	0.993	0.000
C26.1 Spleen	0.007	0.993	0.000
H60.4 Cholesteatoma of external ear	0.007	0.993	0.000
H72.8 Other perforations of tympanic membrane	0.006	0.993	0.000
H81.4 Vertigo of central origin	0.007	0.993	0.000
H91.8 Other specified hearing loss	0.007	0.993	0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.007	0.993	0.000
H93.3 Disorders of acoustic nerve	0.007	0.993	0.000
S02.61 Fracture of mandible (open)	0.007	0.993	0.000
C21.2 Cloacogenic zone	0.006	0.993	0.000
T78.3 Angioneurotic oedema	0.007	0.993	0.000
T78.4 Allergy, unspecified	0.007	0.993	0.000
S02.1 Fracture of base of skull	0.007	0.993	0.000
J39.2 Other diseases of pharynx	0.006	0.993	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.006	0.994	0.000
H91.0 Ototoxic hearing loss	0.006	0.994	0.000
H93.1 Tinnitus	0.006	0.994	0.000
C24.0 Extrahepatic bile duct	0.006	0.994	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.006	0.994	0.000
H81.1 Benign paroxysmal vertigo	0.006	0.994	0.000
H81.9 Disorder of vestibular function, unspecified	0.006	0.994	0.000
H60.8 Other otitis externa	0.006	0.994	0.000
S01.3 Open wound of ear	0.006	0.994	0.000
S00.3 Superficial injury of nose	0.006	0.994	0.000
S00 Superficial injury of head	0.006	0.994	0.000
J39.0 Retropharyngeal and parapharyngeal abscess	0.006	0.994	0.000
S02.70 Multiple fractures involving skull and facial bones (closed)	0.006	0.994	0.000
H60.2 Malignant otitis externa	0.006	0.994	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.006	0.994	0.000
T78.1 Other adverse food reactions, not elsewhere classified	0.006	0.994	0.000
H65.2 Chronic serous otitis media	0.006	0.994	0.000
C17.0 Duodenum	0.006	0.994	0.000
C21.1 Anal canal	0.006	0.994	0.000
H73.8 Other specified disorders of tympanic membrane	0.006	0.994	0.000
H91.3 Deaf mutism, not elsewhere classified	0.006	0.994	0.000
S01.4 Open wound of cheek and temporomandibular area	0.006	0.994	0.000
H60.0 Abscess of external ear	0.006	0.994	0.000
H65.1 Other acute nonsuppurative otitis media	0.006	0.994	0.000
H90.3 Sensorineural hearing loss, bilateral	0.006	0.994	0.000
S02.0 Fracture of vault of skull	0.006	0.994	0.000
S00.8 Superficial injury of other parts of head	0.006	0.994	0.000
S02.10 Fracture of base of skull (closed)	0.006	0.994	0.000
Q66 Congenital deformities of feet	0.006	0.994	0.000
H60.9 Otitis externa, unspecified	0.006	0.994	0.000
S01.9 Open wound of head, part unspecified	0.006	0.994	0.000
J39.3 Upper respiratory tract hypersensitivity reaction, site unspecified	0.006	0.994	0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.006	0.994	0.000
Q65 Congenital deformities of hip	0.006	0.994	0.000
S02.91 Fracture of skull and facial bones, part unspecified (open)	0.005	0.994	0.000
R45.8 Other symptoms and signs involving emotional state	0.000	0.994	0.006
Q76 Congenital malformations of spine and bony thorax	0.006	0.994	0.000
H90.0 Conductive hearing loss, bilateral	0.005	0.994	0.000
Q76.0 Spina bifida occulta	0.006	0.994	0.000
J39.1 Other abscess of pharynx	0.005	0.994	0.000
S03 Dislocation, sprain and strain of joints and ligaments of head	0.005	0.994	0.000
Q66.8 Other congenital deformities of feet	0.005	0.995	0.000
S02.2 Fracture of nasal bones	0.005	0.995	0.000
H80.8 Other otosclerosis	0.005	0.995	0.000
H80.2 Cochlear otosclerosis	0.005	0.995	0.000
H80.1 Otosclerosis involving oval window, obliterative	0.005	0.995	0.000
H80.0 Otosclerosis involving oval window, nonobliterative	0.005	0.995	0.000
S02.4 Fracture of malar and maxillary bones	0.005	0.995	0.000
S05 Injury of eye and orbit	0.005	0.995	0.000
T78.9 Adverse effect, unspecified	0.005	0.995	0.000
Q68 Other congenital musculoskeletal deformities	0.005	0.995	0.000
S08 Traumatic amputation of part of head	0.005	0.995	0.000
S07 Crushing injury of head	0.005	0.995	0.000
S04 Injury of cranial nerves	0.005	0.995	0.000
T78.8 Other adverse effects, not elsewhere classified	0.005	0.995	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.005	0.995	0.000
H65.3 Chronic mucoid otitis media	0.005	0.995	0.000
H90.5 Sensorineural hearing loss, unspecified	0.005	0.995	0.000
S00.2 Other superficial injuries of eyelid and periocular area	0.005	0.995	0.000
S02.8 Fractures of other skull and facial bones	0.005	0.995	0.000
Q74 Other congenital malformations of limb(s)	0.005	0.995	0.000
S02.71 Multiple fractures involving skull and facial bones (open)	0.005	0.995	0.000
H80.9 Otosclerosis, unspecified	0.005	0.995	0.000
S01.1 Open wound of eyelid and periocular area	0.005	0.995	0.000
S02.3 Fracture of orbital floor	0.005	0.995	0.000
H65.0 Acute serous otitis media	0.005	0.995	0.000
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body	0.005	0.995	0.000
Q66.7 Pes cavus	0.005	0.995	0.000
S00.5 Superficial injury of lip and oral cavity	0.005	0.995	0.000
S00.7 Multiple superficial injuries of head	0.005	0.995	0.000
C26.0 Intestinal tract, part unspecified	0.005	0.995	0.000
S02.5 Fracture of tooth	0.005	0.995	0.000
Q24.5 Malformation of coronary vessels	0.005	0.995	0.000
S42.30 Fracture of shaft of humerus (closed)	0.000	0.995	0.005
Q38-Q45 Other congenital malformations of the digestive system	0.005	0.995	0.000
S01.7 Multiple open wounds of head	0.005	0.995	0.000
H60.5 Acute otitis externa, non-infective	0.005	0.995	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.005	0.995	0.000
C22.7 Other specified carcinomas of liver	0.005	0.995	0.000
C22.4 Other sarcomas of liver	0.005	0.995	0.000
C22.3 Angiosarcoma of liver	0.005	0.995	0.000
C22.2 Hepatoblastoma	0.005	0.995	0.000
H81.2 Vestibular neuronitis	0.005	0.995	0.000
Q40 Other congenital malformations of upper alimentary tract	0.005	0.995	0.000
Q70 Syndactyly	0.005	0.995	0.000
Q75 Other congenital malformations of skull and face bones	0.005	0.995	0.000
Q73 Reduction defects of unspecified limb	0.005	0.995	0.000
Q72 Reduction defects of lower limb	0.005	0.995	0.000
Q71 Reduction defects of upper limb	0.005	0.995	0.000
Q69 Polydactyly	0.005	0.995	0.000
Q65.8 Other congenital deformities of hip	0.005	0.995	0.000
Q65.1 Congenital dislocation of hip, bilateral	0.005	0.995	0.000
S02.01 Fracture of vault of skull (open)	0.005	0.995	0.000
H60.3 Other infective otitis externa	0.005	0.995	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.005	0.995	0.000
Q24 Other congenital malformations of heart	0.005	0.995	0.000
Q66.9 Congenital deformity of feet, unspecified	0.005	0.995	0.000
Q78 Other osteochondrodysplasias	0.005	0.995	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.005	0.995	0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.005	0.995	0.000
F01.9 Vascular dementia, unspecified	0.005	0.995	0.000
Q68.8 Other specified congenital musculoskeletal deformities	0.005	0.995	0.000
Q05 Spina bifida	0.005	0.995	0.000
H62.8 Other disorders of external ear in diseases classified elsewhere	0.004	0.995	0.000
H62.4 Otitis externa in other diseases classified elsewhere	0.004	0.995	0.000
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.004	0.995	0.000
H62.2 Otitis externa in mycoses	0.004	0.995	0.000
H62.1 Otitis externa in viral diseases classified elsewhere	0.004	0.995	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.005	0.995	0.000
Q77.4 Achondroplasia	0.004	0.995	0.000
Q40.2 Other specified congenital malformations of stomach	0.004	0.995	0.000
S02.11 Fracture of base of skull (open)	0.004	0.995	0.000
Q66.6 Other congenital valgus deformities of feet	0.004	0.995	0.000
Q66.2 Metatarsus varus	0.004	0.995	0.000
C21.0 Anus, unspecified	0.004	0.995	0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.004	0.995	0.000
Q05.9 Spina bifida, unspecified	0.005	0.995	0.000
T78.0 Anaphylactic shock due to adverse food reaction	0.004	0.995	0.000
Q76.5 Cervical rib	0.004	0.995	0.000
Q00-Q07 Congenital malformations of the nervous system	0.004	0.996	0.000
Q66.5 Congenital pes planus	0.004	0.996	0.000
Q66.4 Talipes calcaneovalgus	0.004	0.996	0.000
Q66.1 Talipes calcaneovarus	0.004	0.996	0.000
S03.2 Dislocation of tooth	0.004	0.996	0.000
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue	0.004	0.996	0.000
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.004	0.996	0.000
Q24.6 Congenital heart block	0.004	0.996	0.000
J98.4 Other disorders of lung	0.004	0.996	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.004	0.996	0.000
H60.1 Cellulitis of external ear	0.004	0.996	0.000
H65.4 Other chronic nonsuppurative otitis media	0.004	0.996	0.000
Q65.9 Congenital deformity of hip, unspecified	0.004	0.996	0.000
Q65.6 Unstable hip	0.004	0.996	0.000
Q65.5 Congenital subluxation of hip, unspecified	0.004	0.996	0.000
Q65.4 Congenital subluxation of hip, bilateral	0.004	0.996	0.000
Q65.3 Congenital subluxation of hip, unilateral	0.004	0.996	0.000
Q65.2 Congenital dislocation of hip, unspecified	0.004	0.996	0.000
Q65.0 Congenital dislocation of hip, unilateral	0.004	0.996	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.004	0.996	0.000
H83 Other diseases of inner ear	0.004	0.996	0.000
Q76.9 Congenital malformation of bony thorax, unspecified	0.004	0.996	0.000
Q76.8 Other congenital malformations of bony thorax	0.004	0.996	0.000
Q76.7 Congenital malformation of sternum	0.004	0.996	0.000
Q76.6 Other congenital malformations of ribs	0.004	0.996	0.000
Q76.3 Congenital scoliosis due to congenital bony malformation	0.004	0.996	0.000
Q76.2 Congenital spondylolisthesis	0.004	0.996	0.000
Q24.4 Congenital subaortic stenosis	0.004	0.996	0.000
Q66.0 Talipes equinovarus	0.004	0.996	0.000
Q74.0 Other congenital malformations of upper limb(s), including shoulder girdle	0.004	0.996	0.000
R45.2 Unhappiness	0.000	0.996	0.004
S05.6 Penetrating wound of eyeball without foreign body	0.004	0.996	0.000
H91.1 Presbycusis	0.004	0.996	0.000
S03.5 Sprain and strain of joints and ligaments of other and unspecified parts of head	0.004	0.996	0.000
S03.4 Sprain and strain of jaw	0.004	0.996	0.000
S03.3 Dislocation of other and unspecified parts of head	0.004	0.996	0.000
S03.1 Dislocation of septal cartilage of nose	0.004	0.996	0.000
S05.9 Injury of eye and orbit, part unspecified	0.004	0.996	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.004	0.996	0.000
Q79.8 Other congenital malformations of musculoskeletal system	0.004	0.996	0.000
S00.9 Superficial injury of head, part unspecified	0.004	0.996	0.000
S62.50 Fracture of thumb (closed)	0.004	0.996	0.000
S05.7 Avulsion of eye	0.004	0.996	0.000
S05.4 Penetrating wound of orbit with or without foreign body	0.004	0.996	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.004	0.996	0.000
K11.2 Sialoadenitis	0.000	0.996	0.004
Q68.5 Congenital bowing of long bones of leg, unspecified	0.004	0.996	0.000
Q68.4 Congenital bowing of tibia and fibula	0.004	0.996	0.000
Q68.3 Congenital bowing of femur	0.004	0.996	0.000
Q68.2 Congenital deformity of knee	0.004	0.996	0.000
Q68.1 Congenital deformity of hand	0.004	0.996	0.000
Q68.0 Congenital deformity of sternocleidomastoid muscle	0.004	0.996	0.000
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle	0.004	0.996	0.000
S04.9 Injury of unspecified cranial nerve	0.004	0.996	0.000
S04.8 Injury of other cranial nerves	0.004	0.996	0.000
S04.7 Injury of accessory nerve	0.004	0.996	0.000
S04.6 Injury of acoustic nerve	0.004	0.996	0.000
S04.5 Injury of facial nerve	0.004	0.996	0.000
S04.4 Injury of abducent nerve	0.004	0.996	0.000
S04.3 Injury of trigeminal nerve	0.004	0.996	0.000
S04.2 Injury of trochlear nerve	0.004	0.996	0.000
S04.1 Injury of oculomotor nerve	0.004	0.996	0.000
S04.0 Injury of optic nerve and pathways	0.004	0.996	0.000
S07.9 Crushing injury of head, part unspecified	0.004	0.996	0.000
S07.8 Crushing injury of other parts of head	0.004	0.996	0.000
S07.1 Crushing injury of skull	0.004	0.996	0.000
S07.0 Crushing injury of face	0.004	0.996	0.000
S08.9 Traumatic amputation of unspecified part of head	0.004	0.996	0.000
S08.8 Traumatic amputation of other parts of head	0.004	0.996	0.000
S08.1 Traumatic amputation of ear	0.004	0.996	0.000
S08.0 Avulsion of scalp	0.004	0.996	0.000
Q74.1 Congenital malformation of knee	0.004	0.996	0.000
Q77.9 Osteochondrodysplasia with defects of growth of tubular bones and spine, unspecified	0.004	0.996	0.000
Q77.8 Other osteochondrodysplasia with defects of growth of tubular bones and spine	0.004	0.996	0.000
Q77.7 Spondyloepiphyseal dysplasia	0.004	0.996	0.000
Q77.6 Chondroectodermal dysplasia	0.004	0.996	0.000
Q77.5 Diastrophic dysplasia	0.004	0.996	0.000
Q77.3 Chondrodysplasia punctata	0.004	0.996	0.000
Q77.2 Short rib syndrome	0.004	0.996	0.000
Q77.1 Thanatophoric short stature	0.004	0.996	0.000
Q77.0 Achondrogenesis	0.004	0.996	0.000
Q40.8 Other specified congenital malformations of upper alimentary tract	0.004	0.996	0.000
Q39 Congenital malformations of oesophagus	0.004	0.996	0.000
S03.0 Dislocation of jaw	0.004	0.996	0.000
S05.1 Contusion of eyeball and orbital tissues	0.004	0.996	0.000
C22.0 Liver cell carcinoma	0.004	0.996	0.000
Q76.1 Klippel-Feil syndrome	0.004	0.996	0.000
Q78.2 Osteopetrosis	0.004	0.996	0.000
Z90.0 Acquired absence of part of head and neck	0.004	0.996	0.000
S02.81 Fractures of other skull and facial bones (open)	0.004	0.996	0.000
Q74.9 Unspecified congenital malformation of limb(s)	0.004	0.996	0.000
Q74.8 Other specified congenital malformations of limb(s)	0.004	0.996	0.000
Q74.3 Arthrogryposis multiplex congenita	0.004	0.996	0.000
S05.3 Ocular laceration without prolapse or loss of intraocular tissue	0.004	0.996	0.000
S00.0 Superficial injury of scalp	0.004	0.996	0.000
B91 Sequelae of poliomyelitis	0.000	0.996	0.004
Q05.4 Unspecified spina bifida with hydrocephalus	0.004	0.996	0.000
Q40.3 Congenital malformation of stomach, unspecified	0.004	0.996	0.000
D51 Vitamin B12 deficiency anaemia	0.004	0.996	0.000
S02.31 Fracture of orbital floor (open)	0.004	0.996	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.004	0.996	0.000
S02.20 Fracture of nasal bones (closed)	0.004	0.996	0.000
S02.41 Fracture of malar and maxillary bones (open)	0.004	0.996	0.000
Q06 Other congenital malformations of spinal cord	0.004	0.996	0.000
S02.00 Fracture of vault of skull (closed)	0.004	0.996	0.000
Q05.7 Lumbar spina bifida without hydrocephalus	0.004	0.996	0.000
Q64.3 Other atresia and stenosis of urethra and bladder neck	0.004	0.996	0.000
Q45 Other congenital malformations of digestive system	0.004	0.996	0.000
Q64 Other congenital malformations of urinary system	0.004	0.996	0.000
S02.51 Fracture of tooth (open)	0.004	0.996	0.000
C22.1 Intrahepatic bile duct carcinoma	0.004	0.996	0.000
S05.5 Penetrating wound of eyeball with foreign body	0.004	0.996	0.000
Q60-Q64 Congenital malformations of the urinary system	0.004	0.996	0.000
S02.21 Fracture of nasal bones (open)	0.004	0.996	0.000
C22.9 Liver, unspecified	0.004	0.996	0.000
C16 Malignant neoplasm of stomach	0.004	0.996	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.004	0.996	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.004	0.996	0.000
I35.2 Aortic (valve) stenosis with insufficiency	0.004	0.996	0.000
Q79.9 Congenital malformation of musculoskeletal system, unspecified	0.004	0.996	0.000
Q79.5 Other congenital malformations of abdominal wall	0.004	0.996	0.000
Q79.4 Prune belly syndrome	0.004	0.996	0.000
Q79.3 Gastroschisis	0.004	0.996	0.000
Q79.2 Exomphalos	0.004	0.996	0.000
Q79.1 Other congenital malformations of diaphragm	0.004	0.996	0.000
Q79.0 Congenital diaphragmatic hernia	0.004	0.996	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.004	0.996	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.004	0.996	0.000
Q43 Other congenital malformations of intestine	0.004	0.996	0.000
Q40.9 Congenital malformation of upper alimentary tract, unspecified	0.004	0.996	0.000
Q40.1 Congenital hiatus hernia	0.004	0.996	0.000
Q40.0 Congenital hypertrophic pyloric stenosis	0.004	0.996	0.000
Q70.9 Syndactyly, unspecified	0.004	0.996	0.000
Q70.4 Polysyndactyly	0.004	0.996	0.000
Q70.3 Webbed toes	0.004	0.996	0.000
Q70.2 Fused toes	0.004	0.996	0.000
Q70.1 Webbed fingers	0.004	0.996	0.000
Q70.0 Fused fingers	0.004	0.996	0.000
Q38.7 Pharyngeal pouch	0.004	0.996	0.000
Q69.9 Polydactyly, unspecified	0.004	0.996	0.000
Q69.2 Accessory toe(s)	0.004	0.996	0.000
Q69.1 Accessory thumb(s)	0.004	0.996	0.000
Q69.0 Accessory finger(s)	0.004	0.996	0.000
Q71.9 Reduction defect of upper limb, unspecified	0.004	0.996	0.000
Q71.8 Other reduction defects of upper limb(s)	0.004	0.996	0.000
Q71.6 Lobster-claw hand	0.004	0.996	0.000
Q71.5 Longitudinal reduction defect of ulna	0.004	0.996	0.000
Q71.4 Longitudinal reduction defect of radius	0.004	0.996	0.000
Q71.3 Congenital absence of hand and finger(s)	0.004	0.996	0.000
Q71.2 Congenital absence of both forearm and hand	0.004	0.996	0.000
Q71.1 Congenital absence of upper arm and forearm with hand present	0.004	0.996	0.000
Q71.0 Congenital complete absence of upper limb(s)	0.004	0.996	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations