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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs35242582
log Bayes Factor = 194.11
Chromosome 6   position 32,600,057  (GRCh37) Explore rs35242582 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
K51.9 Ulcerative colitis, unspecified
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
D51 Vitamin B12 deficiency anaemia
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
0.000 0.000 1.000
K51 Ulcerative colitis
1.000 0.000 0.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.000 1.000
# Top node
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
K50.1 Crohn's disease of large intestine
1.000 0.000 0.000
D50-D53 Nutritional anaemias
0.000 0.000 1.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.000 0.000 1.000
K50 Crohn's disease [regional enteritis]
1.000 0.000 0.000
D00-D09 In situ neoplasms
0.000 0.000 1.000
Chapter II Neoplasms
0.000 0.000 1.000
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
Chapter VI Diseases of the nervous system
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
K50-K52 Noninfective enteritis and colitis
1.000 0.000 0.000
E20-E35 Disorders of other endocrine glands
0.000 0.000 1.000
E27 Other disorders of adrenal gland
0.000 0.000 1.000
D07 Carcinoma in situ of other and unspecified genital organs
0.000 0.001 0.999
E27.1 Primary adrenocortical insufficiency
0.000 0.001 0.999
E05.9 Thyrotoxicosis, unspecified
0.000 0.001 0.999
D06 Carcinoma in situ of cervix uteri
0.000 0.001 0.999
D07.1 Vulva
0.000 0.001 0.999
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.001 0.999
D64.9 Anaemia, unspecified
0.000 0.002 0.998
D06.9 Cervix, unspecified
0.000 0.002 0.998
D60-D64 Aplastic and other anaemias
0.000 0.002 0.998
D64 Other anaemias
0.000 0.002 0.998
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.003 0.997
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.000 0.003 0.997
L80-L99 Other disorders of the skin and subcutaneous tissue
0.000 0.004 0.996
E11.9 Without complications
0.000 0.004 0.996
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.004 0.996
E16 Other disorders of pancreatic internal secretion
0.000 0.004 0.996
C80 Malignant neoplasm without specification of site
0.000 0.006 0.994
E16.2 Hypoglycaemia, unspecified
0.000 0.007 0.993
E10.1 With ketoacidosis
0.000 0.008 0.992
K51.4 Pseudopolyposis of colon
0.992 0.008 0.000
C15-C26 Malignant neoplasms of digestive organs
0.000 0.010 0.990
C21 Malignant neoplasm of anus and anal canal
0.000 0.010 0.990
K50.9 Crohn's disease, unspecified
0.990 0.010 0.000
C80.0 Malignant neoplasm, primary site unknown, so stated
0.000 0.011 0.989
E11.3 With ophthalmic complications
0.000 0.011 0.989
E14 Unspecified diabetes mellitus
0.000 0.012 0.988
L97 Ulcer of lower limb, not elsewhere classified
0.000 0.013 0.987
L90 Atrophic disorders of skin
0.000 0.015 0.985
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.015 0.985
G80-G83 Cerebral palsy and other paralytic syndromes
0.000 0.021 0.979
C21.1 Anal canal
0.000 0.021 0.979
C21.0 Anus, unspecified
0.000 0.024 0.976
E50-E64 Other nutritional deficiencies
0.000 0.027 0.973
G00-G09 Inflammatory diseases of the central nervous system
0.000 0.028 0.972
L91 Hypertrophic disorders of skin
0.000 0.029 0.971
L90.0 Lichen sclerosus et atrophicus
0.000 0.029 0.971
D50 Iron deficiency anaemia
0.000 0.031 0.969
E53 Deficiency of other B group vitamins
0.000 0.033 0.967
L92 Granulomatous disorders of skin and subcutaneous tissue
0.000 0.035 0.965
D50.9 Iron deficiency anaemia, unspecified
0.000 0.036 0.964
C44 Other malignant neoplasms of skin
0.964 0.036 0.000
C44.3 Skin of other and unspecified parts of face
0.962 0.038 0.000
E53.8 Deficiency of other specified B group vitamins
0.000 0.039 0.961
C44.2 Skin of ear and external auricular canal
0.959 0.041 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.043 0.957
L91.8 Other hypertrophic disorders of skin
0.000 0.047 0.953
E27.2 Addisonian crisis
0.000 0.053 0.947
G81 Hemiplegia
0.000 0.056 0.944
G00 Bacterial meningitis, not elsewhere classified
0.000 0.064 0.935
K51.5 Mucosal proctocolitis
0.932 0.068 0.000
E14.3 With ophthalmic complications
0.000 0.068 0.932
K51.2 Ulcerative (chronic) proctitis
0.931 0.069 0.000
E21.0 Primary hyperparathyroidism
0.000 0.071 0.929
K90 Intestinal malabsorption
0.000 0.073 0.927
G37 Other demyelinating diseases of central nervous system
0.000 0.075 0.925
C20 Malignant neoplasm of rectum
0.000 0.078 0.922
E10.4 With neurological complications
0.000 0.081 0.919
E14.9 Without complications
0.000 0.084 0.916
G83 Other paralytic syndromes
0.000 0.085 0.915
G81.9 Hemiplegia, unspecified
0.000 0.085 0.915
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.000 0.085 0.915
N48 Other disorders of penis
0.000 0.087 0.913
N48.1 Balanoposthitis
0.000 0.092 0.908
N48.6 Balanitis xerotica obliterans
0.000 0.098 0.902
E10.6 With other specified complications
0.000 0.103 0.897
L50-L54 Urticaria and erythema
0.000 0.104 0.896
E10.5 With peripheral circulatory complications
0.000 0.104 0.896
L92.0 Granuloma annulare
0.000 0.106 0.894
Chapter XXII Codes for special purposes
0.000 0.109 0.891
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.000 0.109 0.891
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified
0.000 0.109 0.891
C79 Secondary malignant neoplasm of other sites
0.000 0.112 0.888
C34 Malignant neoplasm of bronchus and lung
0.000 0.118 0.882
D07.4 Penis
0.000 0.121 0.879
E11.1 With ketoacidosis
0.000 0.127 0.873
L50 Urticaria
0.000 0.129 0.871
E20 Hypoparathyroidism
0.000 0.132 0.868
C44.4 Skin of scalp and neck
0.865 0.135 0.000
L89 Decubitus ulcer
0.000 0.136 0.864
N48.4 Impotence of organic origin
0.000 0.138 0.862
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.000 0.141 0.859
L10-L14 Bullous disorders
0.000 0.142 0.858
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.144 0.856
G37.9 Demyelinating disease of central nervous system, unspecified
0.000 0.145 0.855
G00.1 Pneumococcal meningitis
0.000 0.147 0.853
G00.9 Bacterial meningitis, unspecified
0.000 0.149 0.851
K50.8 Other Crohn's disease
0.850 0.150 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.000 0.150 0.850
C44.7 Skin of lower limb, including hip
0.848 0.152 0.000
G83.1 Monoplegia of lower limb
0.000 0.154 0.846
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.000 0.154 0.846
E10.0 With coma
0.000 0.154 0.846
C79.2 Secondary malignant neoplasm of skin
0.000 0.155 0.845
C44.6 Skin of upper limb, including shoulder
0.845 0.155 0.000
E16.1 Other hypoglycaemia
0.000 0.160 0.840
K51.0 Ulcerative (chronic) enterocolitis
0.838 0.162 0.000
C80.9 Malignant neoplasm, unspecified
0.000 0.163 0.837
E10.2 With renal complications
0.000 0.170 0.830
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.171 0.829
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.000 0.174 0.826
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.177 0.823
L90.5 Scar conditions and fibrosis of skin
0.000 0.184 0.816
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.190 0.810
D52 Folate deficiency anaemia
0.000 0.192 0.808
C17 Malignant neoplasm of small intestine
0.000 0.193 0.807
E11.5 With peripheral circulatory complications
0.000 0.193 0.807
D07.2 Vagina
0.000 0.196 0.804
C34.9 Bronchus or lung, unspecified
0.000 0.196 0.804
C77.0 Lymph nodes of head, face and neck
0.000 0.202 0.798
C77.4 Inguinal and lower limb lymph nodes
0.000 0.202 0.798
J45 Asthma
0.000 0.203 0.797
E05.8 Other thyrotoxicosis
0.000 0.206 0.794
D55-D59 Haemolytic anaemias
0.000 0.206 0.793
L50.0 Allergic urticaria
0.000 0.207 0.793
C23 Malignant neoplasm of gallbladder
0.000 0.212 0.788
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.212 0.788
K90.9 Intestinal malabsorption, unspecified
0.000 0.214 0.786
E10.8 With unspecified complications
0.000 0.215 0.785
C44.5 Skin of trunk
0.785 0.215 0.000
L89.2 Stage III decubitus ulcer
0.000 0.215 0.785
C22.1 Intrahepatic bile duct carcinoma
0.000 0.215 0.785
D80-D89 Certain disorders involving the immune mechanism
0.000 0.217 0.783
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.000 0.218 0.782
L80 Vitiligo
0.000 0.218 0.782
E14.8 With unspecified complications
0.000 0.219 0.781
C34.0 Main bronchus
0.000 0.221 0.779
N48.0 Leukoplakia of penis
0.000 0.223 0.777
E22 Hyperfunction of pituitary gland
0.000 0.224 0.776
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.000 0.225 0.775
E20.9 Hypoparathyroidism, unspecified
0.000 0.225 0.775
C22.9 Liver, unspecified
0.000 0.231 0.769
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.000 0.231 0.769
E53.9 Vitamin B deficiency, unspecified
0.000 0.232 0.768
L91.0 Keloid scar
0.000 0.233 0.767
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.235 0.765
E14.5 With peripheral circulatory complications
0.000 0.237 0.763
D86 Sarcoidosis
0.000 0.240 0.760
L50.9 Urticaria, unspecified
0.000 0.241 0.759
L89.9 Decubitus ulcer and pressure area, unspecified
0.000 0.247 0.753
C21.8 Overlapping lesion of rectum, anus and anal canal
0.000 0.248 0.752
E21.3 Hyperparathyroidism, unspecified
0.000 0.248 0.752
L13 Other bullous disorders
0.000 0.248 0.752
N48.8 Other specified disorders of penis
0.000 0.252 0.748
L88 Pyoderma gangrenosum
0.000 0.256 0.744
E14.1 With ketoacidosis
0.000 0.258 0.742
J45.0 Predominantly allergic asthma
0.000 0.259 0.741
N40-N51 Diseases of male genital organs
0.000 0.261 0.739
D06.0 Endocervix
0.000 0.261 0.738
G82 Paraplegia and tetraplegia
0.000 0.262 0.738
G06 Intracranial and intraspinal abscess and granuloma
0.000 0.265 0.735
C77.8 Lymph nodes of multiple regions
0.000 0.266 0.734
C09 Malignant neoplasm of tonsil
0.000 0.268 0.732
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.000 0.269 0.731
E11.0 With coma
0.000 0.270 0.730
N47 Redundant prepuce, phimosis and paraphimosis
0.000 0.270 0.730
G09 Sequelae of inflammatory diseases of central nervous system
0.000 0.271 0.729
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.272 0.728
K51.1 Ulcerative (chronic) ileocolitis
0.727 0.273 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.000 0.274 0.726
D64.8 Other specified anaemias
0.000 0.277 0.723
D59 Acquired haemolytic anaemia
0.000 0.278 0.722
C79.7 Secondary malignant neoplasm of adrenal gland
0.000 0.279 0.721
L83 Acanthosis nigricans
0.000 0.279 0.721
E11.2 With renal complications
0.000 0.279 0.721
Chapter I Certain infectious and parasitic diseases
0.000 0.281 0.719
N48.5 Ulcer of penis
0.000 0.281 0.719
L95.9 Vasculitis limited to skin, unspecified
0.000 0.282 0.718
D51.8 Other vitamin B12 deficiency anaemias
0.000 0.283 0.717
D51.3 Other dietary vitamin B12 deficiency anaemia
0.000 0.283 0.717
D51.2 Transcobalamin II deficiency
0.000 0.283 0.717
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.283 0.717
E32 Diseases of thymus
0.000 0.283 0.717
E31 Polyglandular dysfunction
0.000 0.283 0.717
E30 Disorders of puberty, not elsewhere classified
0.000 0.283 0.717
E27.5 Adrenomedullary hyperfunction
0.000 0.283 0.717
E27.0 Other adrenocortical overactivity
0.000 0.283 0.717
D07.6 Other and unspecified male genital organs
0.000 0.283 0.716
D07.3 Other and unspecified female genital organs
0.000 0.283 0.716
D07.0 Endometrium
0.000 0.283 0.716
D06.7 Other parts of cervix
0.000 0.284 0.716
D06.1 Exocervix
0.000 0.284 0.716
G37.8 Other specified demyelinating diseases of central nervous system
0.000 0.284 0.716
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.284 0.715
D64.4 Congenital dyserythropoietic anaemia
0.000 0.284 0.715
D64.3 Other sideroblastic anaemias
0.000 0.284 0.715
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.284 0.715
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.284 0.715
D64.0 Hereditary sideroblastic anaemia
0.000 0.284 0.715
E15 Nondiabetic hypoglycaemic coma
0.000 0.285 0.715
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.000 0.286 0.714
L87 Transepidermal elimination disorders
0.000 0.286 0.714
L86 Keratoderma in diseases classified elsewhere
0.000 0.286 0.714
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.286 0.714
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.286 0.714
E16.4 Abnormal secretion of gastrin
0.000 0.286 0.714
E16.3 Increased secretion of glucagon
0.000 0.286 0.714
C34.1 Upper lobe, bronchus or lung
0.000 0.288 0.712
C76 Malignant neoplasm of other and ill-defined sites
0.000 0.288 0.712
C21.2 Cloacogenic zone
0.000 0.290 0.710
L50.1 Idiopathic urticaria
0.000 0.290 0.710
G81.1 Spastic hemiplegia
0.000 0.290 0.710
E14.7 With multiple complications
0.000 0.291 0.709
E14.2 Withrenal complications
0.000 0.291 0.709
E14.0 With coma
0.000 0.291 0.709
G83.4 Cauda equina syndrome
0.000 0.292 0.708
G70-G73 Diseases of myoneural junction and muscle
0.000 0.292 0.708
L90.9 Atrophic disorder of skin, unspecified
0.000 0.294 0.706
L90.8 Other atrophic disorders of skin
0.000 0.294 0.706
L90.6 Striae atrophicae
0.000 0.294 0.706
L90.4 Acrodermatitis chronica atrophicans
0.000 0.294 0.706
L90.3 Atrophoderma of Pasini and Pierini
0.000 0.294 0.706
L90.2 Anetoderma of Jadassohn-Pellizzari
0.000 0.294 0.706
L90.1 Anetoderma of Schweninger-Buzzi
0.000 0.294 0.706
E14.4 With neurological complications
0.000 0.297 0.703
G03 Meningitis due to other and unspecified causes
0.000 0.297 0.703
G36 Other acute disseminated demyelination
0.000 0.299 0.701
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.000 0.299 0.701
C34.3 Lower lobe, bronchus or lung
0.000 0.299 0.701
D09 Carcinoma in situ of other and unspecified sites
0.000 0.300 0.699
G63 Polyneuropathy in diseases classified elsewhere
0.000 0.302 0.698
G83.8 Other specified paralytic syndromes
0.000 0.302 0.698
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.302 0.698
E63 Other nutritional deficiencies
0.000 0.302 0.698
E56 Other vitamin deficiencies
0.000 0.302 0.698
E50 Vitamin A deficiency
0.000 0.302 0.698
E60 Dietary zinc deficiency
0.000 0.302 0.698
E59 Dietary selenium deficiency
0.000 0.302 0.698
E54 Ascorbic acid deficiency
0.000 0.302 0.698
E52 Niacin deficiency [pellagra]
0.000 0.302 0.698
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere
0.000 0.303 0.697
A50-A64 Infections with a predominantly sexual mode of transmission
0.000 0.303 0.697
C09.9 Tonsil, unspecified
0.000 0.304 0.696
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.000 0.305 0.695
D50.1 Sideropenic dysphagia
0.000 0.305 0.695
E53.1 Pyridoxine deficiency
0.000 0.306 0.693
E53.0 Riboflavin deficiency
0.000 0.306 0.693
E24 Cushing's syndrome
0.000 0.306 0.693
L92.2 Granuloma faciale [eosinophilic granuloma of skin]
0.000 0.308 0.692
L92.1 Necrobiosis lipoidica, not elsewhere classified
0.000 0.308 0.692
D63 Anaemia in chronic diseases classified elsewhere
0.000 0.308 0.692
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.309 0.691
C44.8 Overlapping lesion of skin
0.691 0.309 0.000
E13 Other specified diabetes mellitus
0.000 0.310 0.690
E14.6 With other specified complications
0.000 0.312 0.688
B07 Viral warts
0.000 0.313 0.687
E58 Dietary calcium deficiency
0.000 0.313 0.687
K51.8 Other ulcerative colitis
0.686 0.314 0.000
L50.8 Other urticaria
0.000 0.314 0.686
E21.4 Other specified disorders of parathyroid gland
0.000 0.314 0.686
E21.2 Other hyperparathyroidism
0.000 0.314 0.686
N48.2 Other inflammatory disorders of penis
0.000 0.314 0.686
E34 Other endocrine disorders
0.000 0.316 0.683
C07 Malignant neoplasm of parotid gland
0.000 0.317 0.683
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.000 0.319 0.681
E11.8 With unspecified complications
0.000 0.320 0.680
G81.0 Flaccid hemiplegia
0.000 0.323 0.677
A63 Other predominantly sexually transmitted diseases, not elsewhere classified
0.000 0.323 0.677
G02 Meningitis in other infectious and parasitic diseases classified elsewhere
0.000 0.324 0.676
C44.1 Skin of eyelid, including canthus
0.676 0.324 0.000
L13.0 Dermatitis herpetiformis
0.000 0.324 0.676
E11.6 With other specified complications
0.000 0.327 0.673
G83.2 Monoplegia of upper limb
0.000 0.327 0.673
D02 Carcinoma in situ of middle ear and respiratory system
0.000 0.327 0.673
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.000 0.328 0.672
L92.8 Other granulomatous disorders of skin and subcutaneous tissue
0.000 0.328 0.672
C17.9 Small intestine, unspecified
0.000 0.328 0.672
D52.9 Folate deficiency anaemia, unspecified
0.000 0.329 0.671
K90-K93 Other diseases of the digestive system
0.000 0.329 0.671
G00.8 Other bacterial meningitis
0.000 0.329 0.671
G00.3 Staphylococcal meningitis
0.000 0.329 0.671
G00.2 Streptococcal meningitis
0.000 0.329 0.671
G00.0 Haemophilus meningitis
0.000 0.329 0.671
C40-C41 Malignant neoplasms of bone and articular cartilage
0.000 0.329 0.671
L52 Erythema nodosum
0.000 0.330 0.670
A80-A89 Viral infections of the central nervous system
0.000 0.330 0.670
H36.0 Diabetic retinopathy
0.000 0.332 0.668
L92.3 Foreign body granuloma of skin and subcutaneous tissue
0.000 0.332 0.668
D86.0 Sarcoidosis of lung
0.000 0.334 0.666
G01 Meningitis in bacterial diseases classified elsewhere
0.000 0.334 0.666
E07 Other disorders of thyroid
0.000 0.334 0.665
D86.9 Sarcoidosis, unspecified
0.000 0.335 0.665
K90.3 Pancreatic steatorrhoea
0.000 0.335 0.665
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.335 0.665
K90.1 Tropical sprue
0.000 0.335 0.665
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.000 0.336 0.664
C44.9 Malignant neoplasm of skin, unspecified
0.664 0.336 0.000
G37.5 Concentric sclerosis [Balo]
0.000 0.337 0.663
G37.4 Subacute necrotising myelitis
0.000 0.337 0.663
G37.2 Central pontine myelinolysis
0.000 0.337 0.663
G37.1 Central demyelination of corpus callosum
0.000 0.337 0.663
G37.0 Diffuse sclerosis
0.000 0.337 0.663
K90.8 Other intestinal malabsorption
0.000 0.337 0.663
A63.0 Anogenital (venereal) warts
0.000 0.337 0.663
U80 Agent resistant to penicillin and related antibiotics
0.000 0.337 0.663
D70-D77 Other diseases of blood and blood-forming organs
0.000 0.340 0.660
D53 Other nutritional anaemias
0.000 0.341 0.659
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.341 0.659
L95.8 Other vasculitis limited to skin
0.000 0.342 0.658
E51 Thiamine deficiency
0.000 0.342 0.658
U88 Agent resistant to multiple antibiotics
0.000 0.342 0.658
G83.5 Locked-in syndrome
0.000 0.344 0.656
G83.3 Monoplegia, unspecified
0.000 0.344 0.656
G83.0 Diplegia of upper limbs
0.000 0.344 0.656
G04 Encephalitis, myelitis and encephalomyelitis
0.000 0.344 0.656
D04 Carcinoma in situ of skin
0.000 0.344 0.656
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.000 0.344 0.656
C31 Malignant neoplasm of accessory sinuses
0.000 0.344 0.656
C33 Malignant neoplasm of trachea
0.000 0.344 0.656
N45 Orchitis and epididymitis
0.000 0.344 0.656
Chapter XI Diseases of the digestive system
0.000 0.346 0.654
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.000 0.347 0.653
L93 Lupus erythematosus
0.000 0.347 0.653
E25 Adrenogenital disorders
0.000 0.348 0.652
C37 Malignant neoplasm of thymus
0.000 0.348 0.652
D59.1 Other autoimmune haemolytic anaemias
0.000 0.350 0.650
L11 Other acantholytic disorders
0.000 0.352 0.648
D86.1 Sarcoidosis of lymph nodes
0.000 0.352 0.648
C43-C44 Melanoma and other malignant neoplasms of skin
0.390 0.354 0.256
D69 Purpura and other haemorrhagic conditions
0.000 0.354 0.646
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.000 0.355 0.645
C60-C63 Malignant neoplasms of male genital organs
0.000 0.355 0.645
G63.2 Diabetic polyneuropathy
0.000 0.356 0.644
L12 Pemphigoid
0.000 0.357 0.643
N48.9 Disorder of penis, unspecified
0.000 0.357 0.643
L54 Erythema in diseases classified elsewhere
0.000 0.358 0.642
G83.9 Paralytic syndrome, unspecified
0.000 0.359 0.641
C22.7 Other specified carcinomas of liver
0.000 0.361 0.639
C22.4 Other sarcomas of liver
0.000 0.361 0.639
C22.3 Angiosarcoma of liver
0.000 0.361 0.639
C22.2 Hepatoblastoma
0.000 0.361 0.639
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.362 0.638
E03.8 Other specified hypothyroidism
0.000 0.366 0.634
C34.8 Overlapping lesion of bronchus and lung
0.000 0.367 0.633
L89.3 Stage IV decubitus ulcer
0.000 0.369 0.631
Chapter XIV Diseases of the genitourinary system
0.000 0.369 0.631
L20-L30 Dermatitis and eczema
0.000 0.371 0.629
A87 Viral meningitis
0.000 0.375 0.625
L50.6 Contact urticaria
0.000 0.375 0.625
L50.5 Cholinergic urticaria
0.000 0.375 0.625
L50.4 Vibratory urticaria
0.000 0.375 0.625
L50.3 Dermatographic urticaria
0.000 0.375 0.625
L50.2 Urticaria due to cold and heat
0.000 0.375 0.625
E20.8 Other hypoparathyroidism
0.000 0.377 0.623
E20.1 Pseudohypoparathyroidism
0.000 0.377 0.623
E20.0 Idiopathic hypoparathyroidism
0.000 0.377 0.623
L94 Other localised connective tissue disorders
0.000 0.378 0.622
C32 Malignant neoplasm of larynx
0.000 0.381 0.619
C79.9 Secondary malignant neoplasm, unspecified site
0.000 0.384 0.616
C04 Malignant neoplasm of floor of mouth
0.000 0.384 0.616
L14 Bullous disorders in diseases classified elsewhere
0.000 0.385 0.615
H36 Retinal disorders in diseases classified elsewhere
0.000 0.385 0.615
L91.9 Hypertrophic disorder of skin, unspecified
0.000 0.386 0.614
D72 Other disorders of white blood cells
0.000 0.390 0.610
L95.1 Erythema elevatum diutinum
0.000 0.391 0.609
L95.0 Livedoid vasculitis
0.000 0.391 0.609
D69.6 Thrombocytopenia, unspecified
0.000 0.392 0.608
B90-B94 Sequelae of infectious and parasitic diseases
0.000 0.393 0.607
C26 Malignant neoplasm of other and ill-defined digestive organs
0.000 0.394 0.606
G82.4 Spastic tetraplegia
0.000 0.397 0.603
B01 Varicella [chickenpox]
0.000 0.398 0.602
D63.0 Anaemia in neoplastic disease
0.000 0.400 0.600
D86.8 Sarcoidosis of other and combined sites
0.000 0.402 0.597
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess
0.000 0.403 0.597
N00-N08 Glomerular diseases
0.000 0.403 0.596
C17.0 Duodenum
0.000 0.404 0.596
G70 Myasthenia gravis and other myoneural disorders
0.000 0.404 0.596
U89 Agent resistant to other and unspecified antibiotics
0.000 0.404 0.596
C51-C58 Malignant neoplasms of female genital organs
0.000 0.406 0.594
D72.8 Other specified disorders of white blood cells
0.000 0.406 0.594
N49.2 Inflammatory disorders of scrotum
0.000 0.406 0.594
C12 Malignant neoplasm of pyriform sinus
0.000 0.406 0.594
A87.9 Viral meningitis, unspecified
0.000 0.407 0.593
G82.5 Tetraplegia, unspecified
0.000 0.408 0.592
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.409 0.591
G06.2 Extradural and subdural abscess, unspecified
0.000 0.409 0.591
J45.1 Nonallergic asthma
0.000 0.412 0.588
C01 Malignant neoplasm of base of tongue
0.000 0.412 0.588
C17.1 Jejunum
0.000 0.413 0.587
C38 Malignant neoplasm of heart, mediastinum and pleura
0.000 0.414 0.586
C30 Malignant neoplasm of nasal cavity and middle ear
0.000 0.416 0.584
E34.0 Carcinoid syndrome
0.000 0.417 0.583
U80.8 Agent resistant to other penicillin-related antibiotic
0.000 0.417 0.583
E40-E46 Malnutrition
0.000 0.417 0.582
D52.8 Other folate deficiency anaemias
0.000 0.420 0.580
D52.1 Drug-induced folate deficiency anaemia
0.000 0.420 0.580
D52.0 Dietary folate deficiency anaemia
0.000 0.420 0.580
N44 Torsion of testis
0.000 0.421 0.579
C17.8 Overlapping lesion of small intestine
0.000 0.421 0.578
C17.3 Meckel's diverticulum
0.000 0.421 0.578
D59.9 Acquired haemolytic anaemia, unspecified
0.000 0.422 0.578
E29 Testicular dysfunction
0.000 0.423 0.577
H30-H36 Disorders of choroid and retina
0.000 0.424 0.576
K51.3 Ulcerative (chronic) rectosigmoiditis
0.575 0.425 0.000
U80.1 Methicillin resistant agent
0.000 0.425 0.575
D05 Carcinoma in situ of breast
0.000 0.426 0.574
D66 Hereditary factor VIII deficiency
0.000 0.428 0.572
J45.8 Mixed asthma
0.000 0.429 0.571
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.000 0.431 0.569
D57 Sickle-cell disorders
0.000 0.431 0.569
D55 Anaemia due to enzyme disorders
0.000 0.431 0.569
K70-K77 Diseases of liver
0.000 0.433 0.567
N08 Glomerular disorders in diseases classified elsewhere
0.000 0.433 0.567
U81 Agent resistant to vancomycin and related antibiotics
0.000 0.434 0.566
G82.1 Spastic paraplegia
0.000 0.434 0.566
D04.6 Skin of upper limb, including shoulder
0.000 0.435 0.565
L10 Pemphigus
0.000 0.435 0.564
D82 Immunodeficiency associated with other major defects
0.000 0.439 0.561
D81 Combined immunodeficiencies
0.000 0.439 0.561
C13 Malignant neoplasm of hypopharynx
0.000 0.439 0.561
D50.8 Other iron deficiency anaemias
0.000 0.440 0.560
C76.0 Head, face and neck
0.000 0.440 0.560
C91 Lymphoid leukaemia
0.000 0.440 0.560
Chapter VII Diseases of the eye and adnexa
0.000 0.441 0.559
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.000 0.442 0.558
L23 Allergic contact dermatitis
0.000 0.443 0.557
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.443 0.557
E22.8 Other hyperfunction of pituitary gland
0.000 0.443 0.557
C91.1 Chronic lymphocytic leukaemia
0.000 0.443 0.557
C17.2 Ileum
0.000 0.444 0.556
G64 Other disorders of peripheral nervous system
0.000 0.444 0.555
N48.3 Priapism
0.000 0.445 0.555
N05 Unspecified nephritic syndrome
0.000 0.445 0.555
G06.1 Intraspinal abscess and granuloma
0.000 0.447 0.552
U84 Resistance to other antimicrobial drugs
0.000 0.449 0.551
U83 Resistance to other antibiotics
0.000 0.449 0.551
U82 Resistance to betalactam antibiotics
0.000 0.449 0.551
U85 Resistance to antineoplastic drugs
0.000 0.449 0.551
E61 Deficiency of other nutrient elements
0.000 0.451 0.548
C62 Malignant neoplasm of testis
0.000 0.452 0.548
K75 Other inflammatory liver diseases
0.000 0.453 0.547
D86.3 Sarcoidosis of skin
0.000 0.455 0.545
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.455 0.545
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.000 0.455 0.545
E06 Thyroiditis
0.000 0.455 0.544
C10 Malignant neoplasm of oropharynx
0.000 0.457 0.543
E27.8 Other specified disorders of adrenal gland
0.000 0.457 0.543
C44.0 Skin of lip
0.541 0.459 0.000
D69.9 Haemorrhagic condition, unspecified
0.000 0.459 0.541
A15-A19 Tuberculosis
0.000 0.460 0.540
C22.0 Liver cell carcinoma
0.000 0.460 0.540
C11 Malignant neoplasm of nasopharynx
0.000 0.460 0.540
K75.4 Autoimmune hepatitis
0.000 0.461 0.539
L13.9 Bullous disorder, unspecified
0.000 0.461 0.539
L13.8 Other specified bullous disorders
0.000 0.461 0.539
L13.1 Subcorneal pustular dermatitis
0.000 0.461 0.539
E22.1 Hyperprolactinaemia
0.000 0.462 0.538
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.000 0.462 0.538
A60 Anogenital herpesviral [herpes simplex] infections
0.000 0.462 0.537
C76.2 Abdomen
0.000 0.463 0.537
B01.9 Varicella without complications
0.000 0.465 0.535
A86 Unspecified viral encephalitis
0.000 0.466 0.534
L21 Seborrhoeic dermatitis
0.000 0.467 0.533
D00.0 Lip, oral cavity and pharynx
0.000 0.468 0.532
C00 Malignant neoplasm of lip
0.000 0.468 0.532
C79.6 Secondary malignant neoplasm of ovary
0.000 0.470 0.530

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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