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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs35383149
log Bayes Factor = 9.98272
Chromosome 1   position 63,872,032  (GRCh37) Explore rs35383149 on Ensembl!
Variant rs35383149 is part of Cluster X0052

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.999 0.001 0.000
Chapter XX External causes of morbidity and mortality
0.997 0.003 0.000
S20-S29 Injuries to the thorax
0.997 0.003 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.997 0.003 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.993 0.007 0.000
S22.4 Multiple fractures of ribs
0.987 0.013 0.000
S60-S69 Injuries to the wrist and hand
0.984 0.016 0.000
Chapter VI Diseases of the nervous system
0.984 0.016 0.000
S22.40 Multiple fractures of ribs (closed)
0.983 0.017 0.000
M50-M54 Other dorsopathies
0.982 0.018 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.979 0.021 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.977 0.023 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.975 0.025 0.000
T81 Complications of procedures, not elsewhere classified
0.973 0.027 0.000
Chapter I Certain infectious and parasitic diseases
0.972 0.028 0.000
S40-S49 Injuries to the shoulder and upper arm
0.962 0.038 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.959 0.041 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.958 0.042 0.000
M51 Other intervertebral disk disorders
0.954 0.046 0.000
Y43 Primarily systemic agents
0.952 0.048 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.952 0.048 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.951 0.049 0.000
A30-A49 Other bacterial diseases
0.948 0.052 0.000
S42 Fracture of shoulder and upper arm
0.944 0.056 0.000
Y43.3 Other antineoplastic drugs
0.932 0.068 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.930 0.070 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.929 0.071 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.928 0.072 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.924 0.076 0.000
M20-M25 Other joint disorders
0.923 0.077 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.921 0.079 0.000
T90 Sequelae of injuries of head
0.918 0.082 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.915 0.085 0.000
S27 Injury of other and unspecified intrathoracic organs
0.911 0.089 0.000
M25 Other joint disorders, not elsewhere classified
0.908 0.092 0.000
A41 Other septicaemia
0.907 0.093 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.906 0.094 0.000
B35-B49 Mycoses
0.903 0.097 0.000
S61 Open wound of wrist and hand
0.901 0.099 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.899 0.101 0.000
S10-S19 Injuries to the neck
0.897 0.103 0.000
S42.3 Fracture of shaft of humerus
0.895 0.105 0.000
M05-M14 Inflammatory polyarthropathies
0.890 0.110 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.887 0.113 0.000
M51.2 Other specified intervertebral disk displacement
0.887 0.113 0.000
S80-S89 Injuries to the knee and lower leg
0.884 0.116 0.000
M54 Dorsalgia
0.875 0.125 0.000
G40-G47 Episodic and paroxysmal disorders
0.873 0.127 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.871 0.129 0.000
S64 Injury of nerves at wrist and hand level
0.871 0.129 0.000
D70 Agranulocytosis
0.868 0.132 0.000
R94 Abnormal results of function studies
0.865 0.135 0.000
M80-M85 Disorders of bone density and structure
0.860 0.140 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.860 0.140 0.000
S42.30 Fracture of shaft of humerus (closed)
0.859 0.140 0.000
S70-S79 Injuries to the hip and thigh
0.859 0.141 0.000
D50-D53 Nutritional anaemias
0.858 0.142 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.854 0.146 0.000
G40 Epilepsy
0.854 0.146 0.000
M86-M90 Other osteopathies
0.853 0.147 0.000
S22.3 Fracture of rib
0.853 0.147 0.000
R23 Other skin changes
0.852 0.148 0.000
B37 Candidiasis
0.851 0.149 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.844 0.156 0.000
S42.0 Fracture of clavicle
0.844 0.156 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.843 0.157 0.000
V80-V89 Other land transport accidents
0.842 0.158 0.000
D60-D64 Aplastic and other anaemias
0.842 0.158 0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation
0.838 0.162 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.838 0.162 0.000
T90.4 Sequelae of injury of eye and orbit
0.834 0.166 0.000
Chapter XXII Codes for special purposes
0.830 0.170 0.000
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system
0.829 0.171 0.000
A49 Bacterial infection of unspecified site
0.827 0.173 0.000
T87 Complications peculiar to reattachment and amputation
0.826 0.174 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.825 0.175 0.000
Y52 Agents primarily affecting the cardiovascular system
0.823 0.177 0.000
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified
0.822 0.178 0.000
M25.5 Pain in joint
0.819 0.181 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.816 0.184 0.000
T93 Sequelae of injuries of lower limb
0.815 0.184 0.000
G40.9 Epilepsy, unspecified
0.810 0.190 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.805 0.195 0.000
M84 Disorders of continuity of bone
0.805 0.195 0.000
R23.8 Other and unspecified skin changes
0.803 0.197 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.803 0.197 0.000
Y85 Sequelae of transport accidents
0.800 0.200 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.799 0.201 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.799 0.201 0.000
R94.5 Abnormal results of liver function studies
0.798 0.202 0.000
R87 Abnormal findings in specimens from female genital organs
0.796 0.204 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.796 0.204 0.000
S27.0 Traumatic pneumothorax
0.796 0.204 0.000
S67 Crushing injury of wrist and hand
0.795 0.205 0.000
Y86 Sequelae of other accidents
0.795 0.205 0.000
V40-V49 Car occupant injured in transport accident
0.793 0.207 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.792 0.208 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.791 0.209 0.000
V20-V29 Motorcycle rider injured in transport accident
0.791 0.209 0.000
M54.2 Cervicalgia
0.789 0.211 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.788 0.212 0.000
S66.8 Injury of other muscles and tendons at wrist and hand level
0.786 0.214 0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level
0.784 0.216 0.000
S61.0 Open wound of finger(s) without damage to nail
0.783 0.217 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.780 0.220 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.780 0.220 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.780 0.220 0.000
S12 Fracture of neck
0.780 0.220 0.000
B37.8 Candidiasis of other sites
0.778 0.222 0.000
W50-W64 Exposure to animate mechanical forces
0.775 0.225 0.000
S42.00 Fracture of clavicle (closed)
0.772 0.228 0.000
B37.0 Candidal stomatitis
0.771 0.229 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.770 0.229 0.000
G70-G73 Diseases of myoneural junction and muscle
0.770 0.230 0.000
M13 Other arthritis
0.770 0.230 0.000
D51 Vitamin B12 deficiency anaemia
0.769 0.231 0.000
S80 Superficial injury of lower leg
0.769 0.231 0.000
S42.1 Fracture of scapula
0.768 0.231 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.768 0.232 0.000
S64.4 Injury of digital nerve of other finger
0.767 0.233 0.000
S22.1 Multiple fractures of thoracic spine
0.766 0.234 0.000
T90.9 Sequelae of unspecified injury of head
0.762 0.238 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.759 0.241 0.000
M89 Other disorders of bone
0.758 0.242 0.000
S90-S99 Injuries to the ankle and foot
0.755 0.245 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.755 0.245 0.000
M25.8 Other specified joint disorders
0.754 0.246 0.000
G20-G26 Extrapyramidal and movement disorders
0.753 0.247 0.000
T91 Sequelae of injuries of neck and trunk
0.753 0.247 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.753 0.247 0.000
S22.30 Fracture of rib (closed)
0.753 0.247 0.000
T98 Sequelae of other and unspecified effects of external causes
0.753 0.247 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.752 0.248 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.752 0.248 0.000
G54 Nerve root and plexus disorders
0.752 0.248 0.000
D52 Folate deficiency anaemia
0.751 0.249 0.000
D75 Other diseases of blood and blood-forming organs
0.749 0.251 0.000
A40 Streptococcal septicaemia
0.748 0.252 0.000
S61.9 Open wound of wrist and hand, part unspecified
0.747 0.253 0.000
V10-V19 Pedal cyclist injured in transport accident
0.747 0.253 0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract
0.747 0.253 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.745 0.254 0.000
A41.9 Septicaemia, unspecified
0.745 0.255 0.000
Y43.0 Antiallergic and antiemetic drugs
0.745 0.255 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.745 0.255 0.000
S42.4 Fracture of lower end of humerus
0.745 0.255 0.000
M25.3 Other instability of joint
0.744 0.256 0.000
M51.9 Intervertebral disk disorder, unspecified
0.744 0.256 0.000
Y45.1 Salicylates
0.744 0.256 0.000
D63.0 Anaemia in neoplastic disease
0.744 0.256 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.744 0.256 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.743 0.257 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.743 0.257 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.742 0.258 0.000
S27.3 Other injuries of lung
0.742 0.258 0.000
S40 Superficial injury of shoulder and upper arm
0.741 0.259 0.000
M25.4 Effusion of joint
0.740 0.260 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.740 0.260 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.739 0.261 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.739 0.261 0.000
T92 Sequelae of injuries of upper limb
0.737 0.263 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.737 0.263 0.000
M25.7 Osteophyte
0.737 0.263 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.736 0.264 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.735 0.265 0.000
R20 Disturbances of skin sensation
0.734 0.266 0.000
M32 Systemic lupus erythematosus
0.734 0.266 0.000
Y00-Y09 Assault
0.734 0.266 0.000
M70-M79 Other soft tissue disorders
0.733 0.267 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.731 0.269 0.000
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified
0.731 0.269 0.000
M50 Cervical disk disorders
0.730 0.270 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.727 0.273 0.000
M60-M63 Disorders of muscles
0.727 0.273 0.000
M54.22 Cervicalgia (Cervical region)
0.726 0.274 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.725 0.275 0.000
R85 Abnormal findings in specimens from digestive organs and abdominal cavity
0.723 0.277 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.722 0.278 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.719 0.281 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.718 0.282 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.718 0.282 0.000
M40-M43 Deforming dorsopathies
0.718 0.282 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.718 0.282 0.000
G55.2 Nerve root and plexus compressions in spondylosis
0.718 0.282 0.000
T90.2 Sequelae of fracture of skull and facial bones
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.717 0.283 0.000
M23 Internal derangement of knee
0.716 0.284 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.715 0.285 0.000
Y35-Y36 Legal intervention and operations of war
0.715 0.285 0.000
Y10-Y34 Event of undetermined intent
0.715 0.285 0.000
X85-X99 Assault
0.715 0.285 0.000
X50-X57 Overexertion, travel and privation
0.715 0.285 0.000
X30-X39 Exposure to forces of nature
0.715 0.285 0.000
X20-X29 Contact with venomous animals and plants
0.715 0.285 0.000
X10-X19 Contact with heat and hot substances
0.715 0.285 0.000
X00-X09 Exposure to smoke, fire and flames
0.715 0.285 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.715 0.285 0.000
W75-W84 Other accidental threats to breathing
0.715 0.285 0.000
W65-W74 Accidental drowning and submersion
0.715 0.285 0.000
V98-V99 Other and unspecified transport accidents
0.715 0.285 0.000
V95-V97 Air and space transport accidents
0.715 0.285 0.000
V90-V94 Water transport accidents
0.715 0.285 0.000
V70-V79 Bus occupant injured in transport accident
0.715 0.285 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.715 0.285 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.715 0.285 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.715 0.285 0.000
V01-V09 Pedestrian injured in transport accident
0.715 0.285 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.715 0.285 0.000
S26 Injury of heart
0.715 0.285 0.000
S25 Injury of blood vessels of thorax
0.715 0.285 0.000
S24 Injury of nerves and spinal cord at thorax level
0.715 0.285 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.715 0.285 0.000
S21 Open wound of thorax
0.715 0.285 0.000
M25.54 Pain in joint (Hand)
0.713 0.287 0.000
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)
0.713 0.287 0.000
S27.1 Traumatic haemothorax
0.712 0.288 0.000
S22.9 Fracture of bony thorax, part unspecified
0.712 0.288 0.000
S22.8 Fracture of other parts of bony thorax
0.712 0.288 0.000
S22.5 Flail chest
0.712 0.288 0.000
S71 Open wound of hip and thigh
0.711 0.289 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.710 0.290 0.000
M00-M03 Infectious arthropathies
0.709 0.291 0.000
T80.8 Other complications following infusion, transfusion and therapeutic injection
0.708 0.291 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.708 0.292 0.000
Y85.0 Sequelae of motor-vehicle accident
0.708 0.292 0.000
S22.41 Multiple fractures of ribs (open)
0.707 0.292 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.707 0.293 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.707 0.293 0.000
S00-S09 Injuries to the head
0.706 0.294 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.705 0.294 0.000
S65 Injury of blood vessels at wrist and hand level
0.705 0.295 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.702 0.298 0.000
T95 Sequelae of burns, corrosions and frostbite
0.700 0.299 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.700 0.299 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.700 0.299 0.000
R25 Abnormal involuntary movements
0.700 0.300 0.000
G30-G32 Other degenerative diseases of the nervous system
0.700 0.300 0.000
B99-B99 Other infectious diseases
0.700 0.300 0.000
S80.1 Contusion of other and unspecified parts of lower leg
0.700 0.300 0.000
G40.5 Special epileptic syndromes
0.699 0.301 0.000
Y59 Other and unspecified vaccines and biological substances
0.699 0.301 0.000
Y58 Bacterial vaccines
0.699 0.301 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.699 0.301 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.699 0.301 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.699 0.301 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.699 0.301 0.000
Y48 Anaesthetics and therapeutic gases
0.699 0.301 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.699 0.301 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.699 0.301 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.699 0.301 0.000
Y88 Sequelae of surgical and medical care as external cause
0.698 0.301 0.000
T79-T79 Certain early complications of trauma
0.698 0.302 0.000
M10 Gout
0.698 0.302 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.698 0.302 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.698 0.302 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.698 0.302 0.000
B65-B83 Helminthiases
0.697 0.302 0.000
M13.9 Arthritis, unspecified
0.697 0.303 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.697 0.303 0.000
B50-B64 Protozoal diseases
0.697 0.303 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.697 0.303 0.000
A75-A79 Rickettsioses
0.697 0.303 0.000
A70-A74 Other diseases caused by chlamydiae
0.697 0.303 0.000
A65-A69 Other spirochaetal diseases
0.697 0.303 0.000
A20-A28 Certain zoonotic bacterial diseases
0.697 0.303 0.000
A15-A19 Tuberculosis
0.697 0.303 0.000
G82 Paraplegia and tetraplegia
0.697 0.303 0.000
M11 Other crystal arthropathies
0.697 0.303 0.000
S81 Open wound of lower leg
0.696 0.304 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.696 0.304 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.696 0.304 0.000
A49.0 Staphylococcal infection, unspecified
0.695 0.305 0.000
G57 Mononeuropathies of lower limb
0.694 0.306 0.000
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum
0.693 0.307 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.693 0.307 0.000
T66-T78 Other and unspecified effects of external causes
0.693 0.307 0.000
S19 Other and unspecified injuries of neck
0.692 0.308 0.000
M54.6 Pain in thoracic spine
0.692 0.308 0.000
M25.56 Pain in joint (Lower leg)
0.691 0.309 0.000
S41 Open wound of shoulder and upper arm
0.691 0.309 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.691 0.309 0.000
R87.7 Abnormal histological findings
0.690 0.310 0.000
S48 Traumatic amputation of shoulder and upper arm
0.690 0.310 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.690 0.310 0.000
S44 Injury of nerves at shoulder and upper arm level
0.690 0.310 0.000
S47 Crushing injury of shoulder and upper arm
0.690 0.310 0.000
Chapter II Neoplasms
0.690 0.310 0.000
D55-D59 Haemolytic anaemias
0.689 0.311 0.000
B15-B19 Viral hepatitis
0.688 0.312 0.000
M22 Disorders of patella
0.688 0.312 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.687 0.312 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.687 0.313 0.000
S61.8 Open wound of other parts of wrist and hand
0.687 0.313 0.000
M51.3 Other specified intervertebral disk degeneration
0.684 0.316 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.684 0.316 0.000
M51.4 Schmorl's nodes
0.684 0.316 0.000
R94.3 Abnormal results of cardiovascular function studies
0.684 0.316 0.000
M54.4 Lumbago with sciatica
0.684 0.316 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.684 0.316 0.000
Y43.9 Primarily systemic agent, unspecified
0.683 0.317 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.683 0.317 0.000
Y43.6 Enzymes, not elsewhere classified
0.683 0.317 0.000
Y43.5 Acidifying and alkalising agents
0.683 0.317 0.000
Y43.4 Immunosuppressive agents
0.683 0.317 0.000
Y43.2 Antineoplastic natural products
0.683 0.317 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.682 0.317 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.682 0.318 0.000
M14 Arthropathies in other diseases classified elsewhere
0.682 0.318 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.682 0.318 0.000
B44 Aspergillosis
0.680 0.320 0.000
G44 Other headache syndromes
0.680 0.320 0.000
A48 Other bacterial diseases, not elsewhere classified
0.679 0.321 0.000
A44 Bartonellosis
0.679 0.321 0.000
A43 Nocardiosis
0.679 0.321 0.000
A42 Actinomycosis
0.679 0.321 0.000
A39 Meningococcal infection
0.679 0.321 0.000
A37 Whooping cough
0.679 0.321 0.000
A36 Diphtheria
0.679 0.321 0.000
A32 Listeriosis
0.679 0.321 0.000
A31 Infection due to other mycobacteria
0.679 0.321 0.000
A30 Leprosy [Hansen's disease]
0.679 0.321 0.000
A38 Scarlet fever
0.679 0.321 0.000
A35 Other tetanus
0.679 0.321 0.000
A34 Obstetrical tetanus
0.679 0.321 0.000
A33 Tetanus neonatorum
0.679 0.321 0.000
S64.3 Injury of digital nerve of thumb
0.679 0.321 0.000
G41 Status epilepticus
0.678 0.321 0.000
S20 Superficial injury of thorax
0.678 0.322 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.678 0.322 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.678 0.322 0.000
G40.8 Other epilepsy
0.678 0.322 0.000
M54.5 Low back pain
0.677 0.322 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.677 0.323 0.000
S42.9 Fracture of shoulder girdle, part unspecified
0.677 0.323 0.000
S42.8 Fracture of other parts of shoulder and upper arm
0.677 0.323 0.000
S42.7 Multiple fractures of clavicle, scapula and humerus
0.677 0.323 0.000
S14 Injury of nerves and spinal cord at neck level
0.676 0.323 0.000
T21 Burn and corrosion of trunk
0.676 0.323 0.000
Y43.1 Antineoplastic antimetabolites
0.676 0.324 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.675 0.325 0.000
D52.9 Folate deficiency anaemia, unspecified
0.675 0.325 0.000
M90 Osteopathies in diseases classified elsewhere
0.674 0.326 0.000
R22.4 Localised swelling, mass and lump, lower limb
0.674 0.326 0.000
G90-G99 Other disorders of the nervous system
0.674 0.326 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.672 0.328 0.000
T81.9 Unspecified complication of procedure
0.672 0.328 0.000
T87.6 Other and unspecified complications of amputation stump
0.671 0.329 0.000
M34 Systemic sclerosis
0.671 0.329 0.000
T93.1 Sequelae of fracture of femur
0.671 0.329 0.000
G37 Other demyelinating diseases of central nervous system
0.671 0.329 0.000
S62 Fracture at wrist and hand level
0.670 0.329 0.000
S02 Fracture of skull and facial bones
0.670 0.330 0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level
0.670 0.330 0.000
M53 Other dorsopathies, not elsewhere classified
0.670 0.330 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.670 0.330 0.000
S70 Superficial injury of hip and thigh
0.669 0.330 0.000
R26 Abnormalities of gait and mobility
0.669 0.331 0.000
G51 Facial nerve disorders
0.668 0.332 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.667 0.333 0.000
Y89 Sequelae of other external causes
0.666 0.333 0.000
R93.6 Abnormal findings on diagnostic imaging of limbs
0.666 0.334 0.000
R22.2 Localised swelling, mass and lump, trunk
0.666 0.334 0.000
S89 Other and unspecified injuries of lower leg
0.664 0.335 0.000
G58 Other mononeuropathies
0.664 0.336 0.000
S22.0 Fracture of thoracic vertebra
0.664 0.336 0.000
A00-A09 Intestinal infectious diseases
0.664 0.336 0.000
M91-M94 Chondropathies
0.663 0.336 0.000
T93.2 Sequelae of other fractures of lower limb
0.663 0.337 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.662 0.338 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.662 0.338 0.000
M33 Dermatopolymyositis
0.662 0.338 0.000
M30 Polyarteritis nodosa and related conditions
0.662 0.338 0.000
A49.9 Bacterial infection, unspecified
0.661 0.339 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.661 0.339 0.000
S67.0 Crushing injury of thumb and other finger(s)
0.660 0.340 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.660 0.340 0.000
D74 Methaemoglobinaemia
0.660 0.340 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.660 0.340 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.660 0.340 0.000
S12.2 Fracture of other specified cervical vertebra
0.659 0.341 0.000
S22.2 Fracture of sternum
0.659 0.341 0.000
S79 Other and unspecified injuries of hip and thigh
0.659 0.341 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.659 0.341 0.000
R22.3 Localised swelling, mass and lump, upper limb
0.658 0.341 0.000
M89.8 Other specified disorders of bone
0.658 0.342 0.000
T90.8 Sequelae of other specified injuries of head
0.658 0.342 0.000
T90.3 Sequelae of injury of cranial nerves
0.658 0.342 0.000
T90.1 Sequelae of open wound of head
0.658 0.342 0.000
T90.0 Sequelae of superficial injury of head
0.658 0.342 0.000
S68 Traumatic amputation of wrist and hand
0.658 0.342 0.000
R87.6 Abnormal cytological findings
0.657 0.343 0.000
R84 Abnormal findings in specimens from respiratory organs and thorax
0.656 0.344 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.655 0.345 0.000
R86 Abnormal findings in specimens from male genital organs
0.654 0.346 0.000
M13.94 Arthritis, unspecified (Hand)
0.654 0.346 0.000
S60 Superficial injury of wrist and hand
0.653 0.347 0.000
S27.9 Injury of unspecified intrathoracic organ
0.653 0.347 0.000
S27.8 Injury of other specified intrathoracic organs
0.653 0.347 0.000
S27.7 Multiple injuries of intrathoracic organs
0.653 0.347 0.000
S27.6 Injury of pleura
0.653 0.347 0.000
S27.5 Injury of thoracic trachea
0.653 0.347 0.000
S27.4 Injury of bronchus
0.653 0.347 0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.653 0.347 0.000
X60-X84 Intentional self-harm
0.653 0.347 0.000
M51.8 Other specified intervertebral disk disorders
0.652 0.348 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.652 0.348 0.000
B37.3 Candidiasis of vulva and vagina
0.652 0.348 0.000
M50.1 Cervical disk disorder with radiculopathy
0.652 0.348 0.000
D72 Other disorders of white blood cells
0.652 0.348 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.652 0.348 0.000
V89.2 Person injured in unspecified motor-vehicle accident, traffic
0.652 0.348 0.000
M25.50 Pain in joint (Multiple sites)
0.651 0.348 0.000
M21 Other acquired deformities of limbs
0.651 0.349 0.000
M25.9 Joint disorder, unspecified
0.651 0.349 0.000
M25.2 Flail joint
0.651 0.349 0.000
M25.1 Fistula of joint
0.651 0.349 0.000
M25.0 Haemarthrosis
0.651 0.349 0.000
Y45.2 Propionic acid derivatives
0.651 0.349 0.000
B25-B34 Other viral diseases
0.651 0.349 0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)
0.651 0.349 0.000
A41.4 Septicaemia due to anaerobes
0.650 0.350 0.000
A41.3 Septicaemia due to Haemophilus influenzae
0.650 0.350 0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level
0.650 0.350 0.000
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level
0.650 0.350 0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level
0.650 0.350 0.000
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level
0.650 0.350 0.000
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level
0.650 0.350 0.000
A49.8 Other bacterial infections of unspecified site
0.648 0.352 0.000
S86 Injury of muscle and tendon at lower leg level
0.647 0.352 0.000
B48 Other mycoses, not elsewhere classified
0.647 0.353 0.000
B47 Mycetoma
0.647 0.353 0.000
B46 Zygomycosis
0.647 0.353 0.000
B45 Cryptococcosis
0.647 0.353 0.000
B43 Chromomycosis and phaeomycotic abscess
0.647 0.353 0.000
B42 Sporotrichosis
0.647 0.353 0.000
B41 Paracoccidioidomycosis
0.647 0.353 0.000
B40 Blastomycosis
0.647 0.353 0.000
B39 Histoplasmosis
0.647 0.353 0.000
B38 Coccidioidomycosis
0.647 0.353 0.000
B36 Other superficial mycoses
0.647 0.353 0.000
B49 Unspecified mycosis
0.647 0.353 0.000
S61.7 Multiple open wounds of wrist and hand
0.646 0.354 0.000
W00-W19 Falls
0.645 0.355 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.645 0.355 0.000
G52 Disorders of other cranial nerves
0.645 0.355 0.000
A80-A89 Viral infections of the central nervous system
0.644 0.355 0.000
M06 Other rheumatoid arthritis
0.644 0.356 0.000
W20-W49 Exposure to inanimate mechanical forces
0.644 0.356 0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)
0.644 0.356 0.000
S61.1 Open wound of finger(s) with damage to nail
0.643 0.356 0.000
S17 Crushing injury of neck
0.643 0.356 0.000
S15 Injury of blood vessels at neck level
0.643 0.356 0.000
S11 Open wound of neck
0.643 0.356 0.000
S10 Superficial injury of neck
0.643 0.356 0.000
S18 Traumatic amputation at neck level
0.643 0.356 0.000
S16 Injury of muscle and tendon at neck level
0.643 0.356 0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs
0.643 0.357 0.000
S42.10 Fracture of scapula (closed)
0.643 0.357 0.000
V23 Motorcycle rider injured in collision with car, pick-up truck or van
0.643 0.357 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.642 0.358 0.000
S29 Other and unspecified injuries of thorax
0.642 0.358 0.000
S42.31 Fracture of shaft of humerus (open)
0.641 0.358 0.000
S27.2 Traumatic heamopneumothorax
0.640 0.360 0.000
T23 Burn and corrosion of wrist and hand
0.640 0.360 0.000
C50-C50 Malignant neoplasm of breast
0.639 0.361 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.639 0.361 0.000
M12 Other specific arthropathies
0.638 0.362 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.638 0.362 0.000
M08 Juvenile arthritis
0.638 0.362 0.000
T87.4 Infection of amputation stump
0.638 0.362 0.000
G50 Disorders of trigeminal nerve
0.637 0.363 0.000
A41.8 Other specified septicaemia
0.637 0.363 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.637 0.363 0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)
0.637 0.363 0.000
R89 Abnormal findings in specimens from other organs, systems and tissues
0.636 0.364 0.000
R83 Abnormal findings in cerebrospinal fluid
0.636 0.364 0.000
T90.5 Sequelae of intracranial injury
0.636 0.364 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.636 0.364 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.636 0.364 0.000
M07 Psoriatic and enteropathic arthropathies
0.635 0.364 0.000
G72 Other myopathies
0.635 0.365 0.000
S88 Traumatic amputation of lower leg
0.634 0.366 0.000
S87 Crushing injury of lower leg
0.634 0.366 0.000
S85 Injury of blood vessels at lower leg level
0.634 0.366 0.000
S84 Injury of nerves at lower leg level
0.634 0.366 0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee
0.634 0.366 0.000
M75 Shoulder lesions
0.633 0.367 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.632 0.367 0.000
D61 Other aplastic anaemias
0.632 0.368 0.000
R20.2 Paraesthesia of skin
0.631 0.369 0.000
R23.3 Spontaneous ecchymoses
0.630 0.370 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.630 0.370 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.629 0.371 0.000
G59.0 Diabetic mononeuropathy
0.629 0.371 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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